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Polychlorinated biphenyls

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https://www.readbyqxmd.com/read/28089717/persistent-organic-pollutants-pops-in-human-follicular-fluid-and-in-vitro-fertilization-outcomes-a-pilot-study
#1
Michael S Bloom, Victor Y Fujimoto, Robin Storm, Li Zhang, Celeste D Butts, Diana Sollohub, Robert L Jansing
Persistent organic pollutants (POPs) are ubiquitously distributed among the U.S. population and adversely impact human reproduction. These compounds have been detected in human ovarian follicular fluid (FF), where they directly contact a developing oocyte. As a pilot investigation, we measured 43 polychlorinated biphenyl (PCB) congeners, p,p'-dichlorodiphenyltrichloroethane (DDT), and its persistent metabolite p,p'-dichlorodiphenyldichloroethylene (DDE) in residual FF collected from 32 women undergoing in vitro fertilization (IVF)...
January 9, 2017: Reproductive Toxicology
https://www.readbyqxmd.com/read/28089209/assessment-of-seasonal-variations-in-persistent-organic-pollutants-across-the-region-of-tuscany-using-passive-air-samplers
#2
Victor H Estellano, Karla Pozo, Petra Přibylová, Jana Klánová, Ondřej Audy, Silvano Focardi
Concentrations of persistent organic pollutants (POPs) were measured for an entire year in the region of Tuscany, Italy. Passive air samplers consisting of polyurethane foam (PUF) disks were deployed over four sampling periods of 3-5 months from April 2008 to July 2009 in urban (n = 6) and rural (n = 4) sites. The aim of the study was to characterize the spatial and seasonal variations in selected POPs. The POP concentrations (pg m(-3)) in the air were dominated by dichlorodiphenyltrichloroethane and metabolites (DDTs) and polychlorinated biphenyls (∑7PCBs)...
January 11, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28087526/rapid-enrichment-of-dehalococcoides-like-bacteria-by-partial-hydrophobic-separation
#3
Hanna R Temme, Kipp Sande, Tao Yan, Paige J Novak
: Organohalide respiring bacteria can be difficult to enrich and isolate, which can limit research on these important organisms. The goal of this research was to develop a method to rapidly (minutes to days) enrich these organisms from a mixed community. The method presented is based on the hypothesis that organohalide respiring bacteria would be more hydrophobic than other bacteria as they dehalogenate hydrophobic compounds. The developed method tests this hypothesis by separating a portion of putative organohalide respiring bacteria, those phylogenetically related to Dehalococcoides mccartyi, at the interface between a hydrophobic organic solvent and aqueous media...
January 13, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28075418/serum-polychlorinated-biphenyls-increase-and-oxidative-stress-decreases-with-a-protein-pacing-caloric-restriction-diet-in-obese-men-and-women
#4
Feng He, Li Zuo, Emery Ward, Paul J Arciero
The purposes were to compare the effects of a: (1) 12-week P-CR weight loss (WL) diet (Phase 1) between obese men and women and; (2) 52-week modified P-CR (mP-CR) vs. heart healthy (HH) weight maintenance (WM) diet (Phase 2) on serum PCBs and oxidative stress biomarkers (thiobarbituric acid reactive substances, TBARS; total antioxidant capacity, TAC) in 40 obese participants (men, n = 21; women, n = 19). Participants received dietary counseling and monitoring of compliance. PCBs, TBARS, and TAC were assessed at weeks -1 (CON), 12 (WL), and 64 (WM)...
January 10, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28071720/polychlorinated-biphenyls-target-notch-dll-and-vegf-r2-in-the-mouse-placenta-and-human-trophoblast-cell-lines-for-their-anti-angiogenic-effects
#5
Satyan Kalkunte, Zheping Huang, Eliana Lippe, Sunil Kumar, Larry W Robertson, Surendra Sharma
The intrauterine environment is particularly vulnerable to environmental exposures. We previously established a mouse model that provided evidence for pregnancy complications and placental anti-angiogenesis in response to Aroclor 1254 (A-1254), a mixture of polychlorinated biphenyls (PCBs). Importantly, these effects were observed in IL-10(-/-), but not wild type, mice, suggesting that IL-10 deficiency predisposes to pregnancy disruptive effects of environmental toxicants. However, the mechanisms by which PCBs cause anti-angiogenic effects are unclear...
January 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28069368/polychlorinated-dibenzo-p-dioxins-dibenzofurans-and-flame-retardants-in-northern-gannet-morus-bassanus-eggs-from-bonaventure-island-gulf-of-st-lawrence-1994-2014
#6
Louise Champoux, Jean-François Rail, Raphael A Lavoie
Northern gannet (Morus bassanus) eggs from Bonaventure Island, Québec, Canada, were collected to monitor concentrations of contaminants. Polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDDs/Fs) and non-ortho polychlorinated biphenyls (PCBs) were measured in eggs from 2004 and 2009, and several brominated and nonbrominated flame retardants (FRs) were measured every 2-5 years in eggs from 1994 to 2014. The sum (Σ) concentrations of PCDDs/Fs were significantly lower in 2009 relative to 2004, but the total toxic equivalent concentrations for PCDDs, PCDFs, and PCBs showed no significant differences (196 ng/kg wet weight (ww) in 2004 and 220 ng/kg ww in 2009)...
January 6, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28063657/persistent-organic-pollutants-pops-in-the-atmosphere-of-three-chilean-cities-using-passive-air-samplers
#7
Karla Pozo, Germán Oyola, Victor H Estellano, Tom Harner, Anny Rudolph, Petra Prybilova, Petr Kukucka, Ondrej Audi, Jana Klánová, America Metzdorff, Silvano Focardi
In this study passive air samplers containing polyurethane foam (PUF) disks were deployed in three cities across Chile; Santiago (STG) (n=5, sampling sites), Concepciόn (CON) (n=6) and Temuco (TEM) (n=6) from 2008 to 2009. Polychlorinated biphenyls (PCBs) (7 indicator congeners), chlorinated pesticides hexachlorocyclohexanes (HCHs), dichlorodiphenyl trichloroethanes (DDTs) and flame retardants such as polybrominated diphenyl ethers (PBDEs) were determined by gas chromatography coupled mass spectrometry (GC/MS)...
January 4, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28062097/vicissitudes-of-oxidative-stress-biomarkers-in-the-estuarine-crab-scylla-serrata-with-reference-to-dry-and-wet-weather-conditions-in-ennore-estuary-tamil-nadu-india
#8
M G Ragunathan
The primary objective of this study was to understand the impact of monsoon and summer seasons on the Polychlorinated Biphenyls (PCB's) and petroleum hydrocarbon compounds (PHC's) load in Ennore estuary and how the physiological response of estuarine Scylla serrata inhabiting in this estuary changed with reference to antioxidant defense. Seasonal levels of PCB's and PHC's were assessed in the water along with their bioaccumulation in gills, hemolymph, hepatopancreas and ovary of S. serrata. Concentration of PCB's and PHC's in water and their bioaccumulation was found to be higher in summer season when compared to monsoon season...
January 3, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28059454/cancer-incidence-among-capacitor-manufacturing-workers-exposed-to-polychlorinated-biphenyls
#9
Avima M Ruder, Misty J Hein, Nancy B Hopf, Martha A Waters
BACKGROUND: We evaluated cancer incidence in a cohort of polychlorinated biphenyl (PCB) exposed workers. METHODS: Incident cancers, identified using state registries, were compared to those in a national population using standardized incidence ratios. Trends in prostate cancer incidence with cumulative PCB exposure were evaluated using standardized rate ratios and Cox regression models. For selected sites, cumulative PCB exposure was compared between aggressive (fatal/distant stage) and localized/regional cancers...
January 6, 2017: American Journal of Industrial Medicine
https://www.readbyqxmd.com/read/28051297/source-apportionment-of-atmospheric-polychlorinated-biphenyls-in-new-jersey-1997-2011
#10
Pornsawai Praipipat, Qing Yu Meng, Robert J Miskewitz, Lisa A Rodenburg
Concentrations of polychlorinated biphenyls (PCBs) in the Delaware River currently exceed the Water Quality Criteria of 16 pg/L for the sum of PCBs due in part to atmospheric deposition. The purpose of this work was to use a source apportionment tool called Positive Matrix Factorization (PMF) to identify the sources of PCBs to the atmosphere in this area and determine whether their concentrations are declining over time. The data set was compiled by the Delaware Atmospheric Deposition Network (DADN) from samples taken in Camden, NJ from 1999 to 2011 and New Brunswick, NJ from 1997 to 2011...
January 4, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28050770/managing-dredged-material-in-the-coastal-zone-of-the-baltic-sea
#11
Marta Staniszewska, Helena Boniecka
This article deals with the legal and practical recommendations for the management of dredged material in the riparian countries of the Baltic Sea. The recommendations are contained in three conventions: LC, 2000. London Convention (1972), Convention on the Protection of the Marine Environment of the Baltic Sea area (Helsinki Convention) (1992), the OSPAR Convention (1972). Different approaches to evaluating the contamination level of dredge spoils, used by the Baltic Sea riparian countries, have been characterized...
January 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28043376/disorders-in-barrier-protein-mrna-expression-and-placenta-secretory-activity-under-the-influence-of-polychlorinated-biphenyls-in%C3%A2-vitro
#12
A Wojciechowska, J Mlynarczuk, J Kotwica
Pregnancy disorders are often correlated with the presence of organic pollutants in the tissues of living bodies. The aim of this study was to investigate the effects (over 24 and 48 hours) of polychlorinated biphenyls (PCBs) 153, 126, and 77 at doses of 1, 10, and 100 ng/mL on barrier function and secretory activity in cow placentome sections collected during the second trimester of pregnancy. None of the PCBs affected the viability of the sections (P > 0.05). Polychlorinated biphenyl 153 decreased (P < 0...
February 2017: Theriogenology
https://www.readbyqxmd.com/read/28040638/consumption-of-lake-ontario-sport-fish-and-the-incidence-of-colorectal-cancer-in-the-new-york-state-angler-cohort-study-nysacs
#13
Catherine L Callahan, John E Vena, Joseph Green, Mya Swanson, Lina Mu, Matthew R Bonner
Fish consumption is hypothesized to reduce the risk of colorectal cancer. Nonetheless, consuming sport fish from the Great Lakes increases exposure to certain persistent organic pollutants, namely polychlorinated biphenyls (PCBs) and organochlorine insecticides, which may increase the risk of cancer. Evidence that exposure to persistent organic pollutants is associated with colorectal cancer is sparse. We examined colorectal cancer incidence in the New York State Angler Cohort Study (NYSACS), a prospective cohort of 17,110 anglers and spouses age 18-40 years at enrollment...
December 29, 2016: Environmental Research
https://www.readbyqxmd.com/read/28038879/microbial-polychlorinated-biphenyl-dechlorination-in-sediments-by-electrical-stimulation-the-effect-of-adding-acetate-and-nonionic-surfactant
#14
Hui Yu, Hui Wan, Chunhua Feng, Xiaoyun Yi, Xiaoping Liu, Yuan Ren, Chaohai Wei
The necessity for developing an efficient and cost-effective in situ bioremediation technology for sediments contaminated with polychlorinated biphenyls (PCBs) has prompted the application of low-voltage electrical fields to anaerobic digestion systems. Here we show that the use of a sediment-based bio-electrochemical reactor (BER) poised at a potential of -0.50V (vs. a standard calomel electrode, SCE) substantially enhanced the reduction of 2,3,4,5-tetrachlorobiphenyl (PCB 61) when acetate was added as a carbon source...
December 27, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/28038482/microsomal-metabolism-of-prochiral-polychlorinated-biphenyls-results-in-the-enantioselective-formation-of-chiral-metabolites
#15
Eric Uwimana, Anna M Maiers, Xueshu Li, Hans-Joachim Lehmler
Polychlorinated biphenyl (PCB) congeners with multiple ortho chlorine substituents and their metabolites exist as stable rotational isomers, or atropisomers, that are non-superimposable mirror images of each other. Additionally, the oxidation of certain axially prochiral PCBs, such as 2,2',4,6'-tetrachlorobiphenyl (PCB 51) and 2,2',4,5,6'-pentachlorobiphenyl (PCB 102), in meta position of the symmetrically substituted phenyl ring is expected to form axially chiral hydroxylated metabolites (OH-PCBs); however, the formation of chiral OH-PCBs from prochiral PCBs has not been demonstrated experimentally...
December 30, 2016: Environmental Science & Technology
https://www.readbyqxmd.com/read/28033572/persistent-organic-pollutants-heavy-metals-and-radioactivity-in-the-urban-soil-of-pri%C3%A5-tina-city-kosovo-and-metohija
#16
Ljiljana Gulan, Biljana Milenkovic, Tijana Zeremski, Gordana Milic, Biljana Vuckovic
Polycyclic aromatic hydrocarbons (PAHs), organochlorine pesticides (OCPs), polychlorinated biphenyls (PCBs), heavy metals content and radioactivity levels were measured in 27 soil samples collected from Priština, the capital of Kosovo and Metohija. The sixteen PAHs, twelve OCPs and six PCBs congeners were determined by gas chromatography system with mass spectrometry detection. Although the use of PCBs and OCPs was prohibited decades ago residues of those compounds still existed in measurable concentrations in soils of Priština...
December 22, 2016: Chemosphere
https://www.readbyqxmd.com/read/28033525/dietary-polychlorinated-biphenyls-long-chain-n-3-polyunsaturated-fatty-acids-and-incidence-of-malignant-melanoma
#17
Carolina Donat-Vargas, Marika Berglund, Anders Glynn, Alicja Wolk, Agneta Åkesson
BACKGROUND: For malignant melanoma, other risk factors aside from sun exposure have been hardly explored. Polychlorinated biphenyls (PCBs)-mainly from fatty fish- may affect melanogenesis and promote melanoma progression, while long-chain n-3 polyunsaturated fatty acids seem to exert antineoplastic actions in melanoma cells. OBJECTIVES: We aimed to assess the association of validated estimates of dietary PCB exposure as well as the intake of eicosapentaenoic acid and docosahexaenoic acid (EPA-DHA), accounting for sun habits and skin type, with the risk of malignant melanoma in middle-aged and elderly women...
December 26, 2016: European Journal of Cancer
https://www.readbyqxmd.com/read/28029781/aryl-hydrocarbon-receptor-activation-contributes-to-benzanthrone-induced-hyperpigmentation-via-modulation-of-melanogenic-signaling-pathways
#18
Sabiya Abbas, Shamshad Alam, Krishna P Singh, Mahadeo Kumar, Shailendra K Gupta, Kausar M Ansari
Benzanthrone (BA), an oxidized polycyclic aromatic hydrocarbon (PAH), has been found to be a potential health threat to occupational workers involved in dye manufacturing factories. It has been observed that occupational workers become exposed to BA either during manufacturing, pulverization, or storage and developed various kinds of skin diseases like contact dermatitis, itching, erythema, roughness, and foremost, hyperpigmentation. It has been shown that some environmental organic pollutants (POPs) like dioxins, furans, and polychlorinated biphenyls (PCBs) may act as ligands for the aryl hydrocarbon receptor (AhR) and regulate hyperpigmentation...
January 12, 2017: Chemical Research in Toxicology
https://www.readbyqxmd.com/read/28027704/local-impacts-global-sources-the-governance-of-boundary-crossing-chemicals
#19
Hugh S Gorman, Valoree S Gagnon, Emma S Norman
Over the last half century, a multijurisdictional, multiscale system of governance has emerged to address concerns associated with toxic chemicals that have the capacity to bioaccumulate in organisms and biomagnify in food chains, leading to fish consumption advisories. Components of this system of governance include international conventions (such as the Stockholm Convention on Persistent Organic Pollutants and the Minamata Convention on Mercury), laws enacted by nation states and their subjurisdictions, and efforts to adaptively manage regional ecosystems (such as the U...
December 2016: History of Science; An Annual Review of Literature, Research and Teaching
https://www.readbyqxmd.com/read/28024226/pcb-concentrations-in-women-based-on-breastfeeding-history-nhanes-2001-2004
#20
Cecilia S Alcala, Linda J Phillips
Data from the 2001-2004 National Health and Nutrition Examination Survey (NHANES) were used to evaluate serum concentrations of polychlorinated biphenyls (PCBs) in women of reproductive age, with or without a history of breastfeeding. Analytical data for PCBs 138, 153, and 180 were used along with responses to the NHANES Reproductive Health questions: [Have you] breastfed any of your children? " and "[What] number of children [have been] breastfed [for] at least 1 month? " PCB concentrations were found to be significantly lower among 15-44 year old women who had a history of breastfeeding compared to those who had not breastfed any of their children...
December 23, 2016: Environmental Research
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