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https://www.readbyqxmd.com/read/27913846/potent-mutagenicity-of-some-non-planar-tri-and-tetrachlorinated-biphenyls-in-mammalian-cells-human-cyp2e1-being-a-major-activating-enzyme
#1
Yungang Liu, Keqi Hu, Hansi Jia, Guifang Jin, Hansruedi Glatt, Hao Jiang
Polychlorinated biphenyls (PCBs) have been classified as human carcinogens. Mutagenicity of lower chlorinated biphenyls as well as activation of transcription factors by some other congeners may contribute to the carcinogenicity of PCBs. Recently, we reported that human CYP2E1 activates mono- and dichlorobiphenyls to mutagens. However, mutagenicity of other PCBs and the involvement of other CYPs remained unknown. In this study, Chinese hamster V79-derived cell lines genetically engineered for expression of individual human CYP enzymes and a human hepatocyte (L-02) line endogenously expressing various CYPs were used to determine the activities of several tri- and tetrachlorobiphenyls to induce micronuclei and gene mutations...
December 2, 2016: Archives of Toxicology
https://www.readbyqxmd.com/read/27912912/passive-air-sampling-of-persistent-organic-pollutants-pops-and-emerging-compounds-in-kolkata-megacity-and-rural-mangrove-wetland-sundarban-in-india-an-approach-to-regional-monitoring
#2
Karla Pozo, Santosh Kumar Sarkar, Victor H Estellano, Soumita Mitra, Ondrej Audi, Petr Kukucka, Petra Přibylová, Jana Klánová, Simonetta Corsolini
Polyurethane foam (PUF) disk passive air samplers were deployed concurrently at five sites across Kolkata megacity and the rural mangrove wetland of Sundarban (UNESCO World Heritage Site) between January-March in 2014. Samples were analyzed for hexachlorocyclohexanes (HCHs), dichlorodiphenyltricholoroethanes (DDTs), polychlorinated biphenyls (PCBs) and, polybrominated diphenyl ethers (PBDEs) using gas chromatography and mass spectrometry (GC-MS). Derived air concentrations (pg/m(3)) for Kolkata ranged: for ∑α- and γ-HCH between 70 and 207 (114 ± 62), ∑6DDTs: 127-216 (161 ± 36), ∑7PCBs: 53-213 (141 ± 64), and ∑10PBDEs: 0...
November 29, 2016: Chemosphere
https://www.readbyqxmd.com/read/27908667/concentrations-of-polychlorinated-dibenzodioxins-polychlorodibenzofurans-and-polychlorobiphenyls-in-women-of-reproductive-age-in-italy-a-human-biomonitoring-study
#3
Anna Maria Ingelido, Vittorio Abate, Annalisa Abballe, Fulvia Lucia Albano, Tatiana Battista, Valter Carraro, Michele Conversano, Rosa Corvetti, Silvia De Luca, Silva Franchini, Anna Rita Fulgenzi, Laura Giambanco, Nicola Iacovella, Anna Laura Iamiceli, Antonio Maiorana, Francesco Maneschi, Valentina Marra, Flavia Pirola, Maria Grazia Porpora, Enrico Procopio, Nicola Suma, Silvia Valentini, Luisa Valsenti, Valerio Vecchiè, Elena De Felip
BACKGROUND: Polychlorinated dibenzodioxins (PCDDs), polychlorodibenzofurans (PCDFs), and polychlorobiphenyls (PCBs) are persistent organic pollutants that represent a major concern for women of reproductive age because of the neurodevelopmental effects associated to perinatal exposure. OBJECTIVES: This study was aimed at characterizing exposure of women of reproductive age to PCDDs, PCDFs, and PCBs as a function of residence in different Italian Regions, in areas at presumable different environmental contamination and human exposure to these pollutants...
November 24, 2016: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/27904926/polychlorinated-biphenyl-bioaccumulation-patterns-among-lake-erie-lower-trophic-level-consumers-reflect-species-ecologies
#4
Jordan A Pitt, Ken G Drouillard, Gordon Paterson
Polychlorinated biphenyl (PCB) concentrations were quantified in lower trophic level consumers of the Lake Erie western basin food web to assess the capacity of PCBs to discriminate among trophically similar species inhabiting different compartments of the same ecosystem. Zooplankton were characterized by higher proportions of less chlorinated and hydrophobic homologs relative to zebra mussel (Dreissena polymorpha), mayfly (Hexagenia limbata) and emerald shiner (Notropis atherinoides) samples. PCB biota-sediment accumulation factors (BSAF) differed significantly among species with zebra mussels and emerald shiners having the highest BSAFs...
November 30, 2016: Bulletin of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/27904751/association-of-serum-concentrations-of-persistent-organic-pollutants-pops-and-risk-of-pre-eclampsia-a-case-control-study
#5
Bita Eslami, Hossein Malekafzali, Noushin Rastkari, Batool Hossein Rashidi, Abolghasem Djazayeri, Kazem Naddafi
BACKGROUND: There is increasing evidence that persistent organic pollutants (POPs) may contribute to pre-eclampsia. The objective of this study was to evaluate the association between Polychlorinated Biphenyls (PCBs) and Polybrominated Diphenyl Ethers (PBDEs) as POPs with pre-eclampsia. METHODS: This case-control study was performed in the three general university hospitals of Tehran University of Medical Sciences. Serum samples were collected from cases (n = 45) who had diagnosed with preeclampsia and from control samples (n = 70) with normal pregnancy and attended the same hospital for a routine prenatal visit at the third trimester of pregnancy...
2016: Journal of Environmental Health Science & Engineering
https://www.readbyqxmd.com/read/27903868/allee-effect-in-polar-bears-a-potential-consequence-of-polychlorinated-biphenyl-contamination
#6
Viola Pavlova, Jacob Nabe-Nielsen, Rune Dietz, Christian Sonne, Volker Grimm
Polar bears (Ursus maritimus) from East Greenland and Svalbard exhibited very high concentrations of polychlorinated biphenyls (PCBs) in the 1980s and 1990s. In Svalbard, slow population growth during that period was suspected to be linked to PCB contamination. In this case study, we explored how PCBs could have impacted polar bear population growth and/or male reproductive success in Svalbard during the mid-1990s by reducing the fertility of contaminated males. A dose-response relationship linking the effects of PCBs to male polar bear fertility was extrapolated from studies of the effects of PCBs on sperm quality in rodents...
November 30, 2016: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/27899239/avoid-the-pcb-mistakes-a-more-sustainable-future-for-ionic-liquids
#7
REVIEW
Gregory Chatel, Emmanuel Naffrechoux, Micheline Draye
Based on our original knowledge and experience on both polychlorinated biphenyls (PCBs) identification in aquatic ecosystems, and use of ionic liquids (ILs) as solvents and/or co-catalysts in green chemistry, we drawn a dared comparison between these two families. Indeed, PCBs has been used during several decades for their new properties, but are now considered as prevalent and persistent pollutants; some toxic effects on environment or human are still revealed. ILs, often designated as "green solvents" are increasingly used in numerous applications, but few studies reported about their environmental impact are still controversial...
November 21, 2016: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/27894756/bioremediation-of-long-term-pcb-contaminated-soil-by-white-rot-fungi
#8
Tatiana Stella, Stefano Covino, Monika Čvančarová, Alena Filipová, Maurizio Petruccioli, Alessandro D'Annibale, Tomáš Cajthaml
The objective of this work was to test the PCB-degrading abilities of two white-rot fungi, namely Pleurotus ostreatus and Irpex lacteus, in real contaminated soils with different chemical properties and autochthonous microflora. In addition to the efficiency in PCB removal, attention was given to other important parameters, such as changes in the toxicity and formation of PCB transformation products. Moreover, structural shifts and dynamics of both bacterial and fungal communities were monitored using next-generation sequencing and phospholipid fatty acid analysis...
November 17, 2016: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/27894695/the-performance-of-atmospheric-pressure-gas-chromatography-tandem-mass-spectrometry-compared-to-gas-chromatography-high-resolution-mass-spectrometry-for-the-analysis-of-polychlorinated-dioxins-and-pcbs-in-food-and-feed-samples
#9
Guillaume Ten Dam, Igor Cabreira Pussente, Georges Scholl, Gauthier Eppe, Alexander Schaechtele, Stefan van Leeuwen
Recently, gas chromatography tandem mass spectrometry (GC-MS/MS) has been added in European Union (EU) legislation as an alternative to magnetic sector high resolution mass spectrometry (HRMS) for the analysis of dioxins and dioxin like polychlorinated biphenyls (dl-PCB) in food and feed. In this study the performance of APGC-MS/MS compared to GC-HRMS is investigated and compared with EU legislation. The study includes the legislative parameters, relative intermediate precision standard deviation (SRw,rel), trueness, sensitivity, linear range and ion ratio tolerance...
November 22, 2016: Journal of Chromatography. A
https://www.readbyqxmd.com/read/27894056/traditional-and-new-pops-in-environments-along-the-bohai-and-yellow-seas-an-overview-of-china-and-south-korea
#10
Jing Meng, Seongjin Hong, Tieyu Wang, Qifeng Li, Seo Joon Yoon, Yonglong Lu, John P Giesy, Jong Seong Khim
Rapid economic growth during the past two decades in the region surrounding the Bohai and Yellow Seas has resulted in severe pollution. Large amounts of monitoring data on persistent organic pollutants (POPs) in various environmental media have been accumulated, which allows us to conduct a fairly comprehensive assessment of the region around the Bohai and Yellow Seas to elucidate spatial patterns of pollution on a regional scale. This review summarized distributions of traditional and new POPs, including organochlorine pesticides (OCPs), polychlorinated biphenyls (PCBs), polybrominated diphenyl ethers (PBDEs), hexabromocyclododecanes (HBCDs), and perfluoroalkyl substances (PFASs), in various environmental media...
November 25, 2016: Chemosphere
https://www.readbyqxmd.com/read/27890414/developmental-neurotoxicants-in-human-milk-comparison-of-levels-and-intakes-in-three-european-countries
#11
Eliška Čechová, Martin Scheringer, Marta Seifertová, Ondřej Mikeš, Kristýna Kroupová, Jan Kuta, Joan Forns, Merete Eggesbø, Ilona Quaak, Marijke de Cock, Margot van de Bor, Henrieta Patayová, Ľubica Palkovičová Murínová, Anton Kočan
Developmental neurotoxicants (DNTs), such as methylmercury (MeHg), polychlorinated biphenyls (PCBs) and selected organochlorine pesticides (OCPs), have gained increasing interest recently due to their possible relation to developmental disorders in children, which are increasing worldwide. We analyzed levels of 14 developmental neurotoxicants in human milk samples from Slovakia (n=37), the Netherlands (n=120) and Norway (n=388). Positive identification for most target analytes was >95% in all samples. In all three countries MeHg was measured for the first time in mother milk...
November 24, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27889511/historical-sources-of-polychlorinated-biphenyls-to-the-sediment-of-the-new-york-new-jersey-harbor
#12
Lisa A Rodenburg, David K Ralston
Using dated sediment cores, polychlorinated biphenyl (PCB) congener concentrations in the New York/New Jersey Harbor and Lower Hudson River were investigated using Positive Matrix Factorization. Of the seven factors resolved, six represent Aroclors in various stages of weathering. Factor 1 resembles Aroclor 1242 and is consistent with the Upper Hudson River PCB signal associated with the General Electric capacitor plants near Hudson Falls, NY. This factor is the dominant source of PCBs in the upper layers of the sediment core collected in the Lower Hudson River...
November 24, 2016: Chemosphere
https://www.readbyqxmd.com/read/27888480/serum-concentrations-of-polychlorinated-biphenyls-pcbs-in-a-lebanese-population-enasb-study
#13
Mireille Harmouche-Karaki, Joseph Matta, Khalil Helou, Yara Mahfouz, Nicole Fakhoury-Sayegh, Jean François Narbonne
Polychlorinated biphenyls (PCBs) are persistent organic pollutants that are still routinely detected 30 years after their restriction in many countries. PCBs have been associated with several non-communicable diseases. They are best measured via human biomonitoring (HBM). The concentrations of six indicator PCBs (PCBs 28, 52, 101, 138, 153, and 180) were measured in the serum samples of 316 Lebanese students and employees from Saint Joseph University of Beirut, Lebanon, using gas chromatography coupled to an iron trap mass spectrometer detector...
November 25, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27887825/national-investigation-of-semi-volatile-organic-compounds-pahs-ocps-and-pcbs-in-lake-sediments-of-china-occurrence-spatial-variation-and-risk-assessment
#14
Chaocan Li, Shouliang Huo, Zhiqiang Yu, Beidou Xi, Kevin M Yeager, Zhuoshi He, Chunzi Ma, Jingtian Zhang, Fengchang Wu
In this study, a large scale investigation of semi-volatile organic compounds (SVOCs) in sediments from 52 lakes, located in five geographic regions across China, was conducted to assess sediment quality in terms of organic contaminants. Concentrations of polycyclic aromatic hydrocarbons (PAHs), organochlorine pesticides (OCPs), and polychlorinated biphenyls (PCBs) in sediment were found to range between 17.00-6,633, 0.12-45.24, and 0.03-13.99ngg(-1), respectively. Lake sediments from different regions exhibited variation in contamination levels, and in the compositions of isomers...
November 22, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27885579/an-integrated-assessment-of-pollution-and-biological-effects-in-flounder-mussels-and-sediment-in-the-southern-baltic-sea-coastal-area
#15
Henryka Dabrowska, Orest Kopko, Kari K Lehtonen, Thomas Lang, Ilona Waszak, Maija Balode, Evita Strode
Organic and metal contaminants and biological effects were investigated in flounder, mussels, and sediments in the southern Baltic Sea coastal area in order to assess environmental quality status in that area. Four sites were selected, including two within the Gulf of Gdańsk (GoG). In biota and sediment at each site, DDTs dominated over PCBs and PBDEs were the least abundant among organic contaminants. Their concentrations decreased progressively outward from GoG. Among metal contaminants, the levels of Hg, Pb, and Cd were elevated in GoG...
November 24, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27884466/linking-pollutant-exposure-of-humpback-whales-breeding-in-the-indian-ocean-to-their-feeding-habits-and-feeding-areas-off-antarctica
#16
Krishna Das, Govindan Malarvannan, Alin Dirtu, Violaine Dulau, Magali Dumont, Gilles Lepoint, Philippe Mongin, Adrian Covaci
Humpback whales, Megaptera novaeangliae, breeding off la Reunion Island (Indian Ocean) undergo large-scale seasonal migrations between summer feeding grounds near Antarctica and their reproductive winter grounds in the Indian Ocean. The main scope of the current study was to investigate chemical exposure of humpback whales breeding in the Indian Ocean by providing the first published data on this breeding stock concerning persistent organic pollutants (POPs), namely polychlorinated biphenyls (PCBs), hexachlorobenzene (HCB), hexachlorocyclohexanes (HCHs), DDT and its metabolites (DDTs), chlordane compounds (CHLs), polybrominated diphenyl ethers (PBDEs), and methoxylated PBDEs (MeO-PBDEs)...
November 21, 2016: Environmental Pollution
https://www.readbyqxmd.com/read/27879172/polychlorobiphenyls-in-freshwater-fish-a-new-strategy-to-set-maximum-contamination-limits
#17
Virginie Desvignes, Aurélie Mahé, Xavier Laffray, Carole Vigreux-Besret, Cyril Feidt, Pierre-Marie Badot, Jean-Luc Volatier, Gilles Rivière
Polychlorinated biphenyls (PCBs) are persistent organic pollutants accumulating along the food chain and particularly in fish. Consequently, the European Commission has set regulatory limits for PCBs in both sea and freshwater fish. Focusing on freshwater fish, the French Agency for Food Environmental and Occupational Health & Safety has developed a method to determine the areas in France where the consumption of locally caught freshwater fish is not recommended due to PCB contamination. To determine these areas of potential health concern, an existing statistical model of the relationship between the consumption of local fish by freshwater anglers and their PCB body burden is linked to a newly determined critical PCB body burden threshold for the population...
November 23, 2016: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/27876566/a-novel-recovery-method-of-copper-from-waste-printed-circuit-boards-by-supercritical-methanol-process-preparation-of-ultrafine-copper-materials
#18
Fu-Rong Xiu, Huiwei Weng, Yingying Qi, Gending Yu, Zhigang Zhang, Fu-Shen Zhang, Mengjun Chen
In this study, supercritical methanol (SCM) process was successfully used for the preparation of ultrafine copper materials from waste printed circuit boards (PCBs) after nitric acid pretreatment. Waste PCBs were pretreated twice in nitric acid. Sn and Pb were recovered by the first nitric acid pretreatment. The leach liquor with a high concentration of copper ions after the second nitric acid leaching was subjected to SCM process. The mixture of Cu and Cu2O with poor uniformity of particle size was formed due to the effect of ferric iron contained in the leach liquor of waste PCBs, while more uniform and spherical Cu particles with high monodispersity and smaller size could be prepared after the removal of Fe...
November 19, 2016: Waste Management
https://www.readbyqxmd.com/read/27876543/in-utero-and-childhood-ddt-dde-pbde-and-pcbs-exposure-and-sex-hormones-in-adolescent-boys-the-chamacos-study
#19
Brenda Eskenazi, Stephen A Rauch, Rachel Tenerelli, Karen Huen, Nina T Holland, Robert H Lustig, Katherine Kogut, Asa Bradman, Andreas Sjodin, Kim G Harley
Dichlorodiphenyltrichloroethane (DDT), polybrominated diphenyl ether (PBDE) flame retardants, and polychlorinated biphenyls (PCBs) are believed to be endocrine-disrupting chemicals (EDCs) in humans and animals. The purpose of this study is to examine the relationship of in utero and childhood exposure to these purported EDCs and reproductive hormones in adolescent boys who participated in CHAMACOS, an ongoing birth cohort in California's Salinas Valley. We measured o,p'- and p,p'-DDT, p,p'- DDE, PBDEs and PCBs in serum collected from mothers during pregnancy or at delivery and from their sons at 9 years...
November 14, 2016: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/27876229/temporal-trends-of-chlorinated-paraffins-and-polychlorinated-biphenyls-in-swiss-soils
#20
Christian Bogdal, Nadja Niggeler, Juliane Glüge, Pascal S Diefenbacher, Daniel Wächter, Konrad Hungerbühler
Persistent organic pollutants (POPs), such as polychlorinated biphenyls (PCBs), are ubiquitous environmental contaminants that have been targeted by national regulations since the 1970-1980s, followed in 2004 by the worldwide regulation under the Stockholm Convention on POPs. However, concerns are growing regarding the emergence of additional POP-like substances, such as chlorinated paraffins (CPs), which have particularly large production volumes. Whereas short-chain CPs (SCCPs) have recently been restricted in Europe and are currently under evaluation for inclusion into the Stockholm Convention, medium-chain CPs (MCCPs) have received little attention...
November 18, 2016: Environmental Pollution
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