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https://www.readbyqxmd.com/read/28238380/organochlorine-pesticide-concentrations-in-pooled-serum-of-people-in-different-age-groups-from-five-chinese-cities
#1
Qinghua Wang, Haodong Yuan, Jun Jin, Peng Li, Yulong Ma, Ying Wang
Organochlorine pesticides (OCPs) were determined in human serum samples pooled by donor age (≥60, 50-59, 40-49, 30-39, and 20-29y). The pooled samples were supplied by hospitals in five Chinese cities, Yitong (Jilin Province), Weifang (Shandong Province), Ganzi (Sichuan Province), Huaihua (Hunan Province), and Lingshui (Hainan Province). p,p'-Dichlorodiphenyldichloroethylene (DDE), hexachlorobenzene (HCB), β-hexachlorocyclohexane (HCH), and endosulfan I were the dominant OCPs in the serum samples. The total OCP concentrations and individual concentrations of p,p'-DDE, HCB, and β-HCH were relatively high compared with concentrations that have been found in other parts of the world...
February 18, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28219247/addressing-analytical-challenges-of-the-environmental-monitoring-for-the-water-framework-directive-erm-ce100-a-new-biota-certified-reference-material
#2
Ioannis Dosis, Marina Ricci, Laszlo Majoros, Roberto Lava, Håkan Emteborg, Andrea Held, Hendrik Emons
In the context of supporting the EU Member States in the implementation of the EU Water Framework Directive (WFD), a project for the production of a fish reference material (ERM-CE100) certified for its content of the two priority substances hexachlorobenzene (HCB) and hexachlorobutadiene (HCBD) was carried out at the Joint Research Centre (JRC) of the European Commission. The starting material was naturally contaminated Wels catfish (Silurus glanis), caught in the Ebro River (Spain). A novel approach for the processing of the fish was tested that resulted in a homogeneous and stable reference material in the form of a wet paste...
February 21, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28215542/hexachlorobenzene-alters-cell-cycle-by-regulating-p27-cyclin-e-cdk2-and-c-src-p27-protein-complexes
#3
C Ventura, M Núñez, V Gaido, C Pontillo, N Miret, A Randi, C Cocca
Hexachlorobenzene (HCB) is an organochlorine pollutant widely distributed in the environment around the entire world. Previous reports from our group and others have demonstrated that this compound is as an endocrine disruptor. We have also reported that HCB presents a co-carcinogenic effect in N-Nitroso-N-methyl-urea-induced mammary tumours in rats. In this work, we studied the effects of HCB on cell cycle progression and cell cycle regulating protein expression in the estrogen-sensitive breast cancer cell line, MCF-7...
February 12, 2017: Toxicology Letters
https://www.readbyqxmd.com/read/28202064/prediagnostic-plasma-concentrations-of-organochlorines-and-risk-of-b-cell-non-hodgkin-lymphoma-in-envirogenomarkers-a-nested-case-control-study
#4
Rachel S Kelly, Hannu Kiviranta, Ingvar A Bergdahl, Domenico Palli, Ann-Sofie Johansson, Maria Botsivali, Paolo Vineis, Roel Vermeulen, Soterios A Kyrtopoulos, Marc Chadeau-Hyam
BACKGROUND: Evidence suggests a largely environmental component to non-Hodgkin's lymphoma (NHL). Persistent organic pollutants (POPs) including polychlorinated biphenyls (PCBs), DDE and HCB have been repeatedly implicated, but the literature is inconsistent and a causal relationship remains to be determined. METHODS: The EnviroGenoMarkers study is nested within two prospective cohorts EPIC-Italy and the Northern Sweden Health and Disease Study. Six PCB congeners, DDE and HCB were measured in blood plasma samples provided at recruitment using gas-chromatography mass spectrometry...
February 16, 2017: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/28192994/cats-internal-exposure-to-selected-brominated-flame-retardants-and-organochlorines-correlated-to-house-dust-and-cat-food
#5
J Norrgran Engdahl, A Bignert, B Jones, I Athanassiadis, Å Bergman, J M Weiss
Pet cats may be used as a biomarker for assessing exposures to organohalogen compounds (OHCs) adsorbed to household dust in home environments. This study explores two exposure routes of OHCs, ingestion of OHCs (i) via house dust and (ii) via cat food. House dust from 17 Swedish homes and serum from the participating families' pet cats were collected, and cat food was purchased matching the diet reported. Paired samples of cat serum, house dust, and cat food were analyzed for brominated flame retardants/natural products (polybrominated diphenyl ethers (PBDEs), decabromobiphenyl (BB-209), decabromodiphenyl ethane (DBDPE), 2,4,6-tribromophenol (2,4,6-TBP), OH-PBDEs) and organochlorines (polychlorinated biphenyls (PCBs), 1,1-bis(4,4'-dichlorodiphenyl)-2,2,2-trichloroethane (4,4'-DDT), 1,1-bis(4,4'-dichlorodiphenyl)-2,2-dichloroethene (4,4'-DDE), hexachlorobenzene (HCB), pentachlorophenol (PCP))...
February 21, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28160993/three-cycles-of-human-biomonitoring-in-flanders-time-trends-observed-in-the-flemish-environment-and-health-study
#6
Greet Schoeters, Eva Govarts, Liesbeth Bruckers, Elly Den Hond, Vera Nelen, Stefaan De Henauw, Isabelle Sioen, Tim S Nawrot, Michelle Plusquin, Annette Vriens, Adrian Covaci, Ilse Loots, Bert Morrens, Dries Coertjens, Nicolas Van Larebeke, Sam De Craemer, Kim Croes, Nathalie Lambrechts, Ann Colles, Willy Baeyens
To follow time trends in exposure to environmental chemicals, three successive campaigns of the Flemish Environment and Health Study (FLEHS) have recruited and sampled in total 5825 participants between 2002 and 2014. Cord samples from newborns, urine and blood samples from 14 to 15 years old adolescents and from adults between 50 and 65 years old were analysed in geographical representative samples of the Flemish population. The data of the different campaigns were considered per age group and per biomarker after adjustment for predefined covariates to take into account differences in characteristics of the study populations over time...
November 18, 2016: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/28135664/reductive-dechlorination-of-hexachlorobenzene-subjected-to-several-conditions-in-a-bioelectrochemical-system
#7
Hui Wang, Shuyu Yi, Xian Cao, Zhou Fang, Xianning Li
A microbial fuel cell (MFC) is a very promising way to remove organic pollutants. Hexachlorobenzene (HCB) is a widely used agricultural pesticide. In this study, single-chamber and membrane-less soil MFCs were constructed. The HCB was degraded to pentachlorobenzene (PeCB), tetrachlorobenzene (TeCB), and trichlorobenzene (TCB) in sequence by a reductive dechlorination process in soil MFCs. The influences of the external resistance, concentration of phosphate buffer, and electrode spacing in soil MFCs on the degradation rate and removal efficiency of HCB were analyzed...
January 27, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28100418/persistent-organic-pollutants-in-the-atlantic-and-southern-oceans-and-oceanic-atmosphere
#8
Jenna L Luek, Rebecca M Dickhut, Michele A Cochran, Renee L Falconer, Henrik Kylin
Persistent organic pollutants (POPs) continue to cycle through the atmosphere and hydrosphere despite banned or severely restricted usages. Global scale analyses of POPs are challenging, but knowledge of the current distribution of these compounds is needed to understand the movement and long-term consequences of their global use. In the current study, air and seawater samples were collected Oct. 2007-Jan. 2008 aboard the Icebreaker Oden en route from Göteborg, Sweden to McMurdo Station, Antarctica. Both air and surface seawater samples consistently contained α-hexachlorocyclohexane (α-HCH), γ-HCH, hexachlorobenzene (HCB), α-Endosulfan, and polychlorinated biphenyls (PCBs)...
January 15, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28094809/genome-wide-identification-evolution-and-expression-analysis-of-ring-finger-protein-genes-in-brassica-rapa
#9
Intikhab Alam, Yan-Qing Yang, Yong Wang, Mei-Lan Zhu, Heng-Bo Wang, Boulos Chalhoub, Yun-Hai Lu
More and more RING finger genes were found to be implicated in various important biological processes. In the present study, a total of 731 RING domains in 715 predicted proteins were identified in Brassica rapa genome (AA, 2n = 20), which were further divided into eight types: RING-H2 (371), RING-HCa (215), RING-HCb (47), RING-v (44), RING-C2 (38), RING-D (10), RING-S/T (5) and RING-G (1). The 715 RING finger proteins were further classified into 51 groups according to the presence of additional domains...
January 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/27993081/contribution-of-persistent-organic-pollutant-exposure-to-the-adipose-tissue-oxidative-microenvironment-in-an-adult-cohort-a-multipollutant-approach
#10
Francisco Artacho-Cordón, Josefa León, José M Sáenz, Mariana F Fernández, Piedad Martin-Olmedo, Nicolás Olea, Juan P Arrebola
Despite growing in vitro and in vivo evidence of the putative role of persistent organic pollutants (POPs) in the induction of oxidative damage in cell structures, this issue has been poorly addressed from an epidemiologic perspective. The aim of this study was to explore associations between adipose tissue POP concentrations and the in situ oxidative microenvironment. A cross-sectional study was conducted in a subsample (n = 271) of a previously established cohort, quantifying levels of eight POPs and four groups of oxidative stress biomarkers in adipose tissue...
December 20, 2016: Environmental Science & Technology
https://www.readbyqxmd.com/read/27992738/concentrations-of-organochlorine-pesticides-in-pooled-human-serum-by-age-and-gender
#11
Aleysha Thomas, Leisa-Maree Leontjew Toms, Fiona A Harden, Peter Hobson, Nicole M White, Kerrie L Mengersen, Jochen F Mueller
Organochlorine pesticides (OCPs) have been used for many decades in Australia with cessation of selected persistent and bioaccumulative OCPs ranging from the 1970s to as recently as 2007. The specific aims of this study were to use samples representative of an Australian population to assess age and gender differences in the concentration of OCPs in human blood sera and to investigate temporal trends in these chemicals. Serum was collected from de-identified, surplus pathology samples over five time periods (2002/03, 2006/07, 2008/09, 2010/11 and 2012/13), with 183 serum pools made from 12,175 individual samples; 26 pools in 2002/03, 85 pools in 2006/07 and 24 pools each in 2008/09, 2010/11 and 2012/13...
April 2017: Environmental Research
https://www.readbyqxmd.com/read/27988186/organochlorine-pesticides-in-tree-bark-and-human-hair-in-yunnan-province-china-concentrations-distributions-and-exposure-pathway
#12
Haodong Yuan, Jun Jin, Yao Bai, Qiuxu Li, Ying Wang, Qinghua Wang
The concentrations and distributions of organochlorine pesticides (OCPs) in West China were investigated and internal and external exposure of humans to OCPs were assessed by analyzing samples of human hair and tree bark collected in Kaiyuan, in Yunnan Province, China. Dichlorodiphenyltrichloroethane and its metabolites (collectively called DDTs), hexachlorocyclohexanes (HCHs), and hexachlorobenzene (HCB) were the dominant OCPs in the human hair and tree bark samples. The mean total DDT, total HCH, and HCB concentrations in the tree bark samples were 298pg/g dry weight (dw), 100pg/g dw, and 183pg/g dw, respectively, and the mean total DDT, total HCH, and HCB concentrations in the hair samples were 2850pg/g dw, 348pg/g dw, and 1026pg/g dw, respectively...
February 15, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/27908622/biomonitoring-of-persistent-organic-pollutants-pops-in-child-populations-living-near-contaminated-sites-in-mexico
#13
R Flores-Ramírez, F J Pérez-Vázquez, M Rodríguez-Aguilar, S E Medellín-Garibay, E Van Brussel, A C Cubillas-Tejeda, L Carrizales-Yáñez, F Díaz-Barriga
The aim of this study was to conduct a POP biomonitoring programme for children in high-risk areas. We evaluated 247 serum samples from children between the ages of 6 and 12years old from two zones in Mexico: (1) indigenous zones, which included Cuatlamayan (CUA), Tocoy (TOC), and Santa Maria Picula (SAM); and (2) industrial zones, which included Tercera Chica (TC), Industrial San Luis (IND) and Rincon de San Jose (SJR); Mundo Nuevo (MN); and Alpuyeca (ALP). Our results showed that α-endosulfan was similar to CUA, TOC, SAM, TC and MN (178...
February 1, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/27900525/in-focus-in-hcb
#14
EDITORIAL
Douglas J Taatjes, Jürgen Roth
No abstract text is available yet for this article.
January 2017: Histochemistry and Cell Biology
https://www.readbyqxmd.com/read/27890414/developmental-neurotoxicants-in-human-milk-comparison-of-levels-and-intakes-in-three-european-countries
#15
Eliška Čechová, Martin Scheringer, Marta Seifertová, Ondřej Mikeš, Kristýna Kroupová, Jan Kuta, Joan Forns, Merete Eggesbø, Ilona Quaak, Marijke de Cock, Margot van de Bor, Henrieta Patayová, Ľubica Palkovičová Murínová, Anton Kočan
Developmental neurotoxicants (DNTs), such as methylmercury (MeHg), polychlorinated biphenyls (PCBs) and selected organochlorine pesticides (OCPs), have gained increasing interest recently due to their possible relation to developmental disorders in children, which are increasing worldwide. We analyzed levels of 14 developmental neurotoxicants in human milk samples from Slovakia (n=37), the Netherlands (n=120) and Norway (n=388). Positive identification for most target analytes was >95% in all samples. In all three countries MeHg was measured for the first time in mother milk...
February 1, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/27884466/linking-pollutant-exposure-of-humpback-whales-breeding-in-the-indian-ocean-to-their-feeding-habits-and-feeding-areas-off-antarctica
#16
Krishna Das, Govindan Malarvannan, Alin Dirtu, Violaine Dulau, Magali Dumont, Gilles Lepoint, Philippe Mongin, Adrian Covaci
Humpback whales, Megaptera novaeangliae, breeding off la Reunion Island (Indian Ocean) undergo large-scale seasonal migrations between summer feeding grounds near Antarctica and their reproductive winter grounds in the Indian Ocean. The main scope of the current study was to investigate chemical exposure of humpback whales breeding in the Indian Ocean by providing the first published data on this breeding stock concerning persistent organic pollutants (POPs), namely polychlorinated biphenyls (PCBs), hexachlorobenzene (HCB), hexachlorocyclohexanes (HCHs), DDT and its metabolites (DDTs), chlordane compounds (CHLs), polybrominated diphenyl ethers (PBDEs), and methoxylated PBDEs (MeO-PBDEs)...
January 2017: Environmental Pollution
https://www.readbyqxmd.com/read/27881186/the-social-network-around-influenza-vaccination-in-health-care-workers-a-cross-sectional-study
#17
Anna Llupià, Joaquim Puig, Guillermo Mena, José M Bayas, Antoni Trilla
BACKGROUND: Influenza vaccination coverage remains low among health care workers (HCWs) in many health facilities. This study describes the social network defined by HCWs' conversations around an influenza vaccination campaign in order to describe the role played by vaccination behavior and other HCW characteristics in the configuration of the links among subjects. METHODS: This study used cross-sectional data from 235 HCWs interviewed after the 2010/2011 influenza vaccination campaign at the Hospital Clinic of Barcelona (HCB), Spain...
November 24, 2016: Implementation Science: IS
https://www.readbyqxmd.com/read/27831922/the-association-between-single-nucleotide-polymorphisms-of-the-apelin-gene-and-diabetes-mellitus-in-a-chinese-population
#18
Hui Zheng, Xiaofang Fan, Xuesong Li, Yu Zhang, Yujuan Fan, Ning Zhang, Yuping Song, Fengdong Ren, Chunfang Shen, Jiayi Shen, Jialin Yang
BACKGROUND: The objective of the study was to analyze the association of apelin gene (APLN) single nucleotide polymorphisms (SNPs) and type 2 diabetes mellitus (T2DM). METHODS: A total of 1966 subjects were enrolled in this study, including 168 cases (first batch), 330 cases (second batch), and 1468 nondiabetic controls. The SNPs in the HapMap-HCB of APLN were detected using Sequenom MassARRAY SNP technology and included rs2281068, rs3115757, rs2235309, and rs2235310...
December 1, 2016: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/27825712/untargeted-metabolomic-analysis-of-human-serum-samples-associated-with-exposure-levels-of-persistent-organic-pollutants-indicate-important-perturbations-in-sphingolipids-and-glycerophospholipids-levels
#19
Daniel Carrizo, Olivier P Chevallier, Jayne V Woodside, Sarah F Brennan, Marie M Cantwell, Geraldine Cuskelly, Christopher T Elliott
Persistent organic pollutants (POPs) are distributed globally and are associated with adverse health effects in humans. A study combining gas chromatography-mass spectrometry (GC-MS), high resolution mass spectrometry (UPLC-QTof-MS) and chemometrics for the analysis of adult human serum samples was undertaken. Levels of serum POPs found were in the low range of what has been reported in similar populations across Europe (median 33.84 p, p'-DDE, 3.02 HCB, 83.55 β-HCH, 246.62 PCBs ng/g lipids). Results indicated that compounds concentrations were significantly different between the two groups of POPs exposure (high vs low) and classes (DDE, β-HCH, HCB, PCBs)...
February 2017: Chemosphere
https://www.readbyqxmd.com/read/27825649/sources-atmospheric-transport-and-deposition-mechanism-of-organochlorine-pesticides-in-soils-of-the-tibetan-plateau
#20
Laiguo Chen, Qianhua Feng, Qiusheng He, Yumei Huang, Yu Zhang, Guo Jiang, Wei Zhao, Bo Gao, Kui Lin, Zhencheng Xu
Because of mountain cold-trapping, the soil in the Tibetan Plateau may be an important global sink of organochlorine pesticides (OCPs). However, there are limited data on OCPs in the soils of the Tibetan Plateau. In addition, the atmospheric transport and deposition mechanisms of OCPs also need to be further studied. In this study, the sampling area covered most regions of the Tibetan Plateau. The detection frequencies of ΣChlordane (sum of trans-chlordane, cis-chlordane and oxychlordane), HCB, ΣNonachlor (sum of trans- and cis-nonachlor), DDTs, ΣEndo (sum of endosulfan-I, endosulfan-II and endosulfate), aldrin, HCHs, ΣHeptachlor (sum of heptachlor and heptachlor epoxide), mirex and dieldrin were 100%, 98...
January 15, 2017: Science of the Total Environment
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