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Zati Sharip, Norbaya Hashim, Saim Suratman
This study investigates the presence and distribution of organochlorine pesticides in streams and the lake in the Sembrong Lake Basin in Malaysia. The catchment of Sembrong Lake has been converted to agricultural areas over the past 30 years, with oil palm plantations and modern agricultural farming being the main land use. Surface water samples were collected from eight sites comprising the stream and lake and analysed for 19 organochlorine pesticides (OCPs). In situ measurement of temperature, dissolved oxygen, pH and conductivity were also undertaken at each site...
October 15, 2017: Environmental Monitoring and Assessment
Biljana D Škrbić, Kiwao Kadokami, Igor Antić, Grigorije Jovanović
This is the first comprehensive study on the occurrence of 940 semi-volatile organic compounds including sterols, polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs), pesticides, plasticizers, and other emerging compounds in 10 river and canal sediments collected in northern Serbia. For quantification of investigated compounds GC-MS-MS (selected reaction monitoring) and GC-MS (using both selected ion monitoring and total ion monitoring) methods were used. The number of detected compounds was in the range of 85-117, while the sum of the concentrations varied from 959 μg/kg dry-wt to 84,445 μg/kg dry-wt...
October 14, 2017: Environmental Science and Pollution Research International
Basile Kamgang, Aurelie P Yougang, Micareme Tchoupo, Jacob M Riveron, Charles Wondji
BACKGROUND: Aedes aegypti and Ae. albopictus are the major epidemic vectors of several arbovirus diseases such as yellow fever, dengue, Zika and chikungunya worldwide. Both Aedes vectors are presents in Cameroon; however, knowledge on the dynamic of the distribution of these species across cities and their resistance profile to insecticide are limited. Here, we assessed the current distribution of Ae. aegypti and Ae. albopictus in Yaoundé, the Capital City, established the resistance profile to insecticides and explored the resistance mechanisms involved...
October 10, 2017: Parasites & Vectors
Christophe Antonio-Nkondjio, N Sonhafouo-Chiana, C S Ngadjeu, P Doumbe-Belisse, A Talipouo, L Djamouko-Djonkam, E Kopya, R Bamou, P Awono-Ambene, Charles S Wondji
BACKGROUND: Malaria remains a major public health threat in Cameroon and disease prevention is facing strong challenges due to the rapid expansion of insecticide resistance in vector populations. The present review presents an overview of published data on insecticide resistance in the main malaria vectors in Cameroon to assist in the elaboration of future and sustainable resistance management strategies. METHODS: A systematic search on mosquito susceptibility to insecticides and insecticide resistance in malaria vectors in Cameroon was conducted using online bibliographic databases including PubMed, Google and Google Scholar...
October 10, 2017: Parasites & Vectors
Marina Gromova, Aurelie Lefrancois, Louis Vaure, Fabio Agnese, Dmitry Aldakov, Axel Maurice, David Djurado, Colette Lebrun, Arnaud de Geyer, Tobias U Schulli, Stéphanie Pouget, Peter Reiss
Ternary metal chalcogenide nanocrystals (NCs) offer exciting opportunities as novel materials to be explored on the nanoscale showing optoelectronic properties tunable with size and composition. CuInS2 (CIS) NCs are the most widely studied representatives of this family as they can be easily prepared with good size control and in high yield by reacting the metal precursors (copper iodide and indium acetate) in dodecanethiol (DDT). Despite the widespread use of this synthesis method both the reaction mechanism and the surface state of the obtained NCs remain elusive...
October 10, 2017: Journal of the American Chemical Society
Yong Sun, Guo-Li Yuan, Jun Li, Jianhui Tang, Gen-Hou Wang
Sediment cores from lakes have been used to reconstruct the historic deposition of persistent organic pollutants (POPs), especially in remote alpine areas. To reconstruct the deposition history of organochlorine pesticides (OCPs) in the Tibetan Plateau (TP), two sediment cores from Yamzho Yumco Lake were drilled and dated with high-resolution, from which 23 OCPs were analyzed in greater detail. Regarding several legacy compounds, concentration peaks in the cores were observed in the 1970s, corresponding to the heavy usage of these compounds around the world...
October 4, 2017: Science of the Total Environment
Kathryn M Rodgers, Julia O Udesky, Ruthann A Rudel, Julia Green Brody
BACKGROUND: Many common environmental chemicals are mammary gland carcinogens in animal studies, activate relevant hormonal pathways, or enhance mammary gland susceptibility to carcinogenesis. Breast cancer's long latency and multifactorial etiology make evaluation of these chemicals in humans challenging. OBJECTIVE: For chemicals previously identified as mammary gland toxicants, we evaluated epidemiologic studies published since our 2007 review. We assessed whether study designs captured relevant exposures and disease features suggested by toxicological and biological evidence of genotoxicity, endocrine disruption, tumor promotion, or disruption of mammary gland development...
October 5, 2017: Environmental Research
Marie-Sophie Garcia-Heras, Beatriz Arroyo, Robert E Simmons, Pablo R Camarero, Rafael Mateo, Francois Mougeot
Persistent pollutants such as organochlorine compounds (OCs) have been highlighted as a cause of population decline in avian predators. Understanding patterns of OCs contamination can be crucial for the conservation of affected species, yet little is known on these threats to African raptors. Here we report on OC concentrations in an endangered predator endemic to southern Africa, the Black Harrier Circus maurus. Blood samples were collected in 2012-2014 from wild nestlings (n = 90) and adults (n = 23) in south-western South Africa, where agriculture and urbanization have developed rapidly since the 1950s...
October 4, 2017: Environmental Pollution
Rehnuma Haque, Tsukasa Inaoka, Miho Fujimura, Akhtar Sk Ahmad, Daisuke Ueno
This study was conducted to make clear the major intake route of DDT in Bangladesh people to develop strategy and policy that could lead to a reduction in body burden especially in the reproductive age women. The concentrations of several POPs (DDT, PCBs, chlordanes, HCHs, HCB, and PeCB) were quantified in food items, human breast milk and house dust collected in Bangladesh in 2011-2012. Among the POPs analyzed in this study, DDT and its metabolites (ΣDDT) showed the highest concentration. The highest median ΣDDT concentration was found in meat (1...
September 13, 2017: Chemosphere
Henk van den Berg, Gamini Manuweera, Flemming Konradsen
BACKGROUND: DDT was among the initial persistent organic pollutants listed under the Stockholm Convention and continues to be used for control of malaria and other vector-borne diseases in accordance with its provisions on acceptable purposes. Trends in the production and use of DDT were evaluated over the period 2001-2014. RESULTS: Available data on global production of DDT showed a 32% decline over the reporting period, from 5144 to 3491 metric tons of active ingredient p...
October 5, 2017: Malaria Journal
Zijian Li
Regulations for pesticides in soil are important for controlling human health risk; humans can be exposed to pesticides by ingesting soil, inhaling soil dust, and through dermal contact. Previous studies focused on analyses of numerical standard values for pesticides and evaluated the same pesticide using different standards among different jurisdictions. To understand the health consequences associated with pesticide soil standard values, lifetime theoretical maximum contribution and risk characterization factors were used in this study to quantify the severity of damage using disability-adjusted life years (DALYs) under the maximum "legal" exposure to persistent organic pollutant (POP) pesticides that are commonly regulated by the Stockholm Convention...
October 2, 2017: Journal of Environmental Management
Xianming Zhang, John Barnes, Ying D Lei, Frank Wania
An air sampling campaign on the Island of Hawaii aimed to assess background concentrations of semivolatile organic compounds (SVOCs) over the Central Northern Pacific and to explore their distribution along an altitudinal transect. XAD-resin-based passive air samplers were deployed from May to September 2011 at six sites along a transect from the northeastern coast to the Mauna Loa Observatory and at three other island sites. By crossing the trade wind inversion, the transect comprised the marine boundary layer and free troposphere...
October 4, 2017: Environmental Science & Technology
Ángel Cruz-Esquivel, Jose Viloria-Rivas, Jose Marrugo-Negrete
Contamination with pesticide residues affects the environmental health of agroecosystems, especially the amphibian fauna that lives in these environments. The objective of the present study was to determine pesticides concentrations in sediments of agroecosystems and to evaluate genetic damage in Rhinella marina populations living in these zones. A total of 91 individuals were collected, 51 in the group exposed in different areas of the middle region of the Sinú River (Irrigation District of Mocari 16, Irrigation District of Aguas Negras 21, Irrigation District of Cerete 14) and 40 in a control group; at the same time, 36 subsamples of sediments were taken at each sampled station to determine pesticides organochlorine by means of chromatography coupled with ISQ Thermo Scientific mass spectrometer...
October 3, 2017: Environmental Science and Pollution Research International
Walter Fabricio Silva Martins, Craig Stephen Wilding, Keith Steen, Henry Mawejje, Tiago Rodrigues Antão, Martin James Donnelly
BACKGROUND: Culex quinquefasciatus collected in Uganda, where no vector control interventions directly targeting this species have been conducted, was used as a model to determine if it is possible to detect heterogeneities in selection pressure driven by insecticide application targeting other insect species. METHODOLOGY/PRINCIPAL FINDINGS: Population genetic structure was assessed through microsatellite analysis, and the impact of insecticide pressure by genotyping two target-site mutations, Vgsc-1014F of the voltage-gated sodium channel target of pyrethroid and DDT insecticides, and Ace1-119S of the acetylcholinesterase gene, target of carbamate and organophosphate insecticides...
October 2017: PLoS Neglected Tropical Diseases
Gyan Chand, Priyamadhaba Behera, Bang Abhay, Neeru Singh
An. culicifacies is the major vector of malaria in tribal community and tribal dominated areas in India. Development of resistance to insecticides is the major challenge to curb the transmission. Gadchiroli (Maharashtra) is a tribal district in central India where incidence of malaria increased from 2012 to 2015 despite indoor space spray with synthetic pyrethroids. To determine the susceptibility status of An. culicifacies against commonly used insecticides in public health program in Gadchiroli. standard WHO method and test kit were used...
October 3, 2017: Pathogens and Global Health
Mei-Hwa Lin, Fei-Yun Liu, Hsiu-Mien Wang, Hsin-Ching Cho, Shyh-Chyi Lo
Daratumumab is a monoclonal immunoglobulin against CD38 and has been approved for treating patients with refractory multiple myeloma. The presence of daratumumab in the sera can interfere with pretransfusion testing due to the weakly expression of CD38 on red cells. The reactivity could be mistaken as autoantibody (if autocontrol is positive) or alloantibody (if autocontrol is negative). We present a case that demonstrates daratumumab could mimic a high titer low avidity (HTLA) alloantibody. A 34-year-old male patient of refractory myeloma was recruited in phase three clinical trial involving daratumumab...
July 2017: Asian Journal of Transfusion Science
Yongqiong Deng, Hong Zhao, Jiyuan Zhou, Linlin Yan, Guiqiang Wang
BACKGROUND: For hepatitis B patients who do not meet the treatment criteria recommended by guidelines, therapy decisions depend on hepatic histology. Angiopoietin-like protein 2 (Angptl2) is a mediator of chronic inflammation that contributes to extracellular matrix remodeling. The aim of this study was to explore the predictive value of Angptl2 as a novel biomarker of liver histology. METHODS: Hepatitis B patients with normal to minimally raised ALT were recruited...
September 29, 2017: BMC Infectious Diseases
AYuan Zhang, Lin Yang, Pengfei Guo, Shaojun Li, Xiaoxiao Ao, Feng Xu, Liping Tan
BACKGROUND: Hand-foot-mouth disease (HFMD) is an acute infectious disease caused by enteroviruses, and HFMD complicated by cardiopulmonary failure has a high mortality. B type natriuretic peptide (BNP) is widely applied in monitoring cardiovascular disorders, and thus, we investigated whether this index was associated with the severity of HFMD and the outcome in severe HFMD. METHODS: Serum BNP, lactate, and glucose levels as well as white blood cell (WBC) count, PaO2/FiO2, and cardiac output (CO) were analyzed in the 83 enrolled HFMD patients according to different conditions (common, severe, and critical; with and without complication; and survivors and non-survivors)...
September 29, 2017: BMC Infectious Diseases
J A O Oyekunle, O A Akindolani, M B Sosan, A S Adekunle
Levels of organochlorine pesticides (OCPs) were determined in dried cocoa beans obtained from cocoa produce stores at Ondo and Ile-Ife, Southwestern Nigeria. Cocoa beans samples were sun dried to a constant weight, pulverized and soxhlet extracted with dichloromethane to obtain the OCPs. Qualitative identification and quantitative evaluation of the extracted OCPs after clean-up on silica gel were accomplished with the aid of a Gas Chromatography coupled with an Electron Capture Detector (GC-ECD). Levels of OCPs in cocoa beans from Ondo had a mean range of ND (p, p'-DDE) to 82...
2017: Toxicology Reports
Maryam Amizadeh, Mohammad Safari-Kamalabadi, Ghasem Askari-Saryazdi, Marzieh Amizadeh, Hamed Reihani-Kermani
INTRODUCTION: Causes of head and neck cancers (HNCs) are multifactorial, and few studies have investigated the association between chemical exposure and HNCs. The objective of this study was to investigate associations between HNCs, agricultural occupations, and pesticide exposure. The potential for the accumulation of pesticides in the adipose tissue of patients was also investigated. MATERIALS AND METHODS: A structured questionnaire was used to collect information on demographics, occupation, and exposure to pesticides in a hospital-based case-control study...
September 2017: Iranian Journal of Otorhinolaryngology
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