Read by QxMD icon Read


Hua Fang, Yanfei Deng, Qiqing Ge, Jiajia Mei, Houpu Zhang, Huifang Wang, Yunlong Yu
The biodegradability and ecological safety assessment of the previously isolated DDT-degrading bacterial strain Stenotrophomonas sp. DDT-1 were investigated in the DDT-contaminated soil under laboratory and field conditions. Under laboratory conditions, the degradation rates of fresh p,p'-DDT in soil were enhanced by 2.0-3.0-fold with the introduction of the strain DDT-1 compared to those of the control treatments. A similar enhancement in the dissipation of DDTs (p,p'-DDT, p,p'-DDE, p,p'-DDD, and o,p'-DDT) in the aged DDT-contaminated field plot soils resulted from the inoculation with this strain...
April 18, 2018: Ecotoxicology and Environmental Safety
Rehnuma Haque, Tsukasa Inaoka, Miho Fujimura, Chiho Watanabe, Akhtar Sk Ahmad, Risa Kakimoto, Momoko Ishiyama, Daisuke Ueno
This research was conducted in order to propose ways to reduce human exposure to DDT, especially for women of reproductive age in Bangladesh, and to find a relation between DDT exposure levels in serum and questionnaire information including sociodemographic and food frequency (FFQ). In this study, a significant relationship was found between the education level and BMI, and the serum p,p'-DDE concentration. This result suggests that people with higher education (relating to higher income) and BMI in Bangladesh actively buy expensive foodstuff, like meat and/or fatty fish, which relates to a higher fat intake...
April 18, 2018: Environmental Science and Pollution Research International
Rachid Jellali, Françoise Gilard, Vittoria Pandolfi, Audrey Legendre, Marie-José Fleury, Patrick Paullier, Cécile Legallais, Eric Leclerc
Despite the diversity of studies on pesticide toxicities, there is a serious lack of information concerning the toxic effect of pesticides mixtures. Dichlorodiphenyl-trichloroethane (DDT) and permethrin (PMT) are among the most prevalent pesticides in the environment and have been the subject of several toxicological studies. However, there are no data on the toxicity of their mixtures. In this study, we used an approach combining cell culture in microfluidic biochips with gas chromatography-mass spectrometry metabolomics profiling to investigate the biomarkers of toxicity of DDT, PMT and their mixtures...
April 16, 2018: Journal of Applied Toxicology: JAT
Keon Mook Seong, Brad S Coates, May R Berenbaum, John M Clark, Barry R Pittendrigh
BACKGROUND: Cytochrome P450 monooxygenases (P450s) are involved in the biosynthesis of endogenous intracellular compounds and the metabolism of xenobiotics, including chemical insecticides. We investigated the structural and expression level variance across all P450 genes with respect to the evolution of insecticide resistance under multigenerational DDT selection. RESULTS: RNA-seq and reverse transcriptase quantitative PCR indicated that the transcript levels of seven P450 genes were significantly up-regulated and three P450 genes were down-regulated in the DDT-resistant strain 91-R, as compared to the control strain 91-C...
April 15, 2018: Pest Management Science
Brenda Eskenazi, Sookee An, Stephen A Rauch, Eric S Coker, Angelina Maphula, Muvhulawa Obida, Madelein Crause, Katherine R Kogut, Riana Bornman, Jonathan Chevrier
BACKGROUND: Although indoor residual spraying (IRS) with dichlorodiphenyltrichloroethane (DDT) and pyrethroids effectively controls malaria, it potentially increases human exposure to these insecticides. Previous studies suggest that prenatal exposure to these insecticides may impact human neurodevelopment. OBJECTIVES: We aimed to estimate the effects of maternal insecticide exposure and neurodevelopment of toddlers living in a malaria-endemic region currently using IRS...
April 6, 2018: Environmental Health Perspectives
Eva Junqué, Mercè Garí, Rosa Maria Llull, Joan O Grimalt
An integrated assessment of lean fish of commercial value as Hg and organochlorine compound source into the population of the Balearic Islands were reported. Dependences between pollutant concentrations, trophic level, fish species, specimen weight and physical-chemical properties were evaluated. Hg and total DDTs showed highest variability between fish species whereas PCBs and HCB displayed more constant median values. The organochlorine compounds found in highest concentrations were those with highest hydrophobicity, consistently with their higher bioaccumulation potential...
April 5, 2018: Science of the Total Environment
Rafael Ogaz-González, Ángel Mérida-Ortega, Luisa Torres-Sánchez, Lourdes Schnaas, César Hernández-Alcaraz, Mariano E Cebrián, Stephen J Rothenberg, Rosa María García-Hernández, Lizbeth López-Carrillo
BACKGROUND: Maternal 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (DDE) serum levels during pregnancy have been negatively linked to child neurodevelopment in contrast to intake of omega-3 and -6 (ω-3 and ω-6) fatty acids. OBJECTIVES: To assess whether maternal dietary intake of ω-3 and ω-6 during pregnancy modifies the association between exposure to DDE and child neurodevelopment from age 42-60 months. METHODS: Prospective cohort study with 142 mother-child pairs performed in Mexico...
April 2, 2018: Environmental Pollution
Katey D Glunt, Shüné V Oliver, Richard H Hunt, Krijn P Paaijmans
BACKGROUND: It is anticipated that malaria elimination efforts in Africa will be hampered by increasing resistance to the limited arsenal of insecticides approved for use in public health. However, insecticide susceptibility status of vector populations evaluated under standard insectary test conditions can give a false picture of the threat, as the thermal environment in which the insect and insecticide interact plays a significant role in insecticide toxicity. METHODS: The effect of temperature on the expression of the standard WHO insecticide resistance phenotype was examined using Anopheles arabiensis and Anopheles funestus strains: a susceptible strain and the derived resistant strain, selected in the laboratory for resistance to DDT or pyrethroids...
April 2, 2018: Malaria Journal
Juhyun Song, Martin Z Bazant
We develop a mathematical framework to analyze electrochemical impedance spectra in terms of a distribution of diffusion times (DDT) for a parallel array of random finite-length Warburg (diffusion) or Gerischer (reaction-diffusion) circuit elements. A robust DDT inversion method is presented based on complex nonlinear least squares regression with Tikhonov regularization and illustrated for three cases of nanostructured electrodes for energy conversion: (i) a carbon nanotube supercapacitor, (ii) a silicon nanowire Li-ion battery, and (iii) a porous-carbon vanadium flow battery...
March 16, 2018: Physical Review Letters
Jennifer C Hartle, Ronald S Cohen, Pauline Sakamoto, Dana Boyd Barr, Suzan L Carmichael
BACKGROUND: Environmental contaminants ranging from legacy chemicals like p,p'-dichlorodiphenyltrichloroethane (DDT) to emerging chemicals like phthalates are ubiquitous. Research aims/questions: This research aims to examine the presence and co-occurrence of contaminants in human milk and effects of pasteurization on human milk chemical contaminants. METHODS: We analyzed human milk donated by 21 women to a milk bank for 23 chemicals, including the persistent organic pollutants (POPs) polychlorinated biphenyls (PCBs), polybrominated diphenyl ethers (PBDEs), dichlorodiphenyltrichloroethane (DDT), and dichlorodiphenyldichloroethylene (DDE) isomers that are known to sequester in adipose tissue, along with the current-use and nonpersistent pesticides chlorpyrifos and permethrin, phthalates, and bisphenol A (BPA)...
March 1, 2018: Journal of Human Lactation: Official Journal of International Lactation Consultant Association
Murugendra Vanarotti, Benjamin J Evison, Marcelo L Actis, Akira Inoue, Ezelle T McDonald, Youming Shao, Richard J Heath, Naoaki Fujii
REV1 protein is a mutagenic DNA damage tolerance (DDT) mediator and encodes two ubiquitin-binding motifs (i.e., UBM1 and UBM2) that are essential for the DDT function. REV1 interacts with K164-monoubiquitinated PCNA (UbPCNA) in cells upon DNA-damaging stress. By using AlphaScreen assays to detect inhibition of REV1 and UbPCNA protein interactions along with an NMR-based strategy, we identified small-molecule compounds that inhibit the REV1/UbPCNA interaction and that directly bind to REV1 UBM2. In cells, one of the compound prevented recruitment of REV1 to PCNA foci on chromatin upon cisplatin treatment, delayed removal of UV-induced cyclopyrimidine dimers from nuclei, prevented UV-induced mutation of HPRT gene, and diminished clonogenic survival of cells that were challenged by cyclophosphamide or cisplatin...
March 19, 2018: Bioorganic & Medicinal Chemistry
Andrews Obeng Affum, Samuel Osafo Acquaah, Shiloh Dede Osae, Edward Ebow Kwaansa-Ansah
The existence of pesticides, such as organochlorine pesticides, parathion-ethyl, methamidophos which is banned globally and some current-use non-banned pesticides of organophosphorus and synthetic pyrethroids in freshwater sources is an ecological and public health concern in many countries, including Ghana. Prompted by this concern, the exposure levels and risk assessment of these pesticides to humans and non-target organisms via groundwater and surface water sources in an agricultural catchment dominated by cocoa crops in the Ankobra Basin, Ghana, were investigated...
March 26, 2018: Science of the Total Environment
Millissia Ben Maamar, Ingrid Sadler-Riggleman, Daniel Beck, Michael K Skinner
A variety of environmental toxicants and factors have been shown to induce the epigenetic transgenerational inheritance of disease and phenotypic variation. Epigenetic alterations in the germline (sperm or egg) are required to transmit transgenerational phenotypes. The current study was designed to investigate the potential role of histones in sperm to help mediate the epigenetic transgenerational inheritance. The agricultural fungicide vinclozolin and the pesticide DDT (dichlorodiphenyltrichloroethane) were independently used to promote the epigenetic transgenerational inheritance of disease...
March 28, 2018: Scientific Reports
Jie Wang, Allison Taylor, Chenye Xu, Daniel Schlenk, Jay Gan
Compared to the total chemical concentration, bioavailability is a better measurement of risks of hydrophobic organic contaminants (HOCs) to biota in contaminated soil or sediment. Many different bioavailability estimation methods have been introduced to assess the effectiveness of remediation treatments. However, to date the different methods have rarely been evaluated against each other, leading to confusions in method selection. In this study, four different bioavailability estimation methods, including solid phase microextraction (SPME) and polyethylene passive sampling (PE) aiming to detect free chemical concentration (Cfree ), and Tenax desorption and isotope dilution method (IDM) aiming to measure chemical accessibility, were used in parallel to estimate in bioavailability of DDT residues (DDXs) in a historically contaminated soil after addition of different black carbon sorbents...
March 24, 2018: Environmental Pollution
N Eevers, J R Hawthorne, J C White, J Vangronsveld, N Weyens
Although the use of the pesticide 2,2-bis(p-chlorophenyl)-1,1,1-trichloroethane (DDT) was banned from the mid-1970s, its most abundant and recalcitrant degradation product, 2,2-bis(p-chlorophenyl)-1,1-dichloro-ethylene (DDE), is still present in terrestrial and aquatic ecosystems worldwide. Zucchini (Cucurbita pepo ssp. pepo) has been shown to accumulate high concentrations of DDE and was proposed for phytoremediation of contaminated soils. We performed a field trial covering a full plant life cycle. C. pepo plants inoculated with the plant growth-promoting endophytic strains Sphingomonas taxi UH1, Methylobacterium radiotolerans UH1, Enterobacter aerogenes UH1, or a consortium combining these 3 strains were grown on a DDE-contaminated field for 100 days...
March 21, 2018: International Journal of Phytoremediation
Ozekeke Ogbeide, Azubuike Chukwuka, Isioma Tongo, Lawrence Ezemonye
Studies on pesticide behavior, adsorption-likelihood, and bioavailability vis-a-vis geosorbent properties and seasons, are critical for understanding pesticide-fate and risks in pesticide-prone environments. We examined the relationship between geosorbent profiles of sediments (percentage sand, silt, clay, organic carbon content) across seasons and occurrence of pesticide residues in surface water and sediment of agricultural catchments at Owan, Ogbesse and Illushi communities of Edo State, Nigeria. Pesticide concentrations were measured monthly in samples of surface water and sediments across the selected sites for 18-months...
March 23, 2018: Journal of Environmental Management
Vasiliy Yu Tsygankov, Olga N Lukyanova, Margarita D Boyarova
Bioaccumulation of organochlorine pesticides by marine organisms is one of the methods of environmental quality. Concentrations of organochlorine pesticides (HCH isomers (α-, β-, γ-HCH), p,p'-DDT and its metabolites (p,p'-DDD, p,p'-DDE)) in samples of seabirds (Northern fulmar Fulmarus glacialis, Crested auklet Aethia cristatella, Auklet-crumb Aethia pusilla, Pacific gull Larus schistisagus, and Gray petrel Oceanodroma furcate) and marine mammals (Gray whales Eschrichtius robustus and Pacific walrus Odobenus rosmarus divergens) were measured by a GC-MS...
March 2018: Marine Pollution Bulletin
Kanthan Nambirajan, Subramanian Muralidharan, Subbian Manonmani, Venkatachalam Kirubhanandhini, Kitusamy Ganesan
Incidences of mortality of Indian peafowl Pavo cristatus, the national bird (Schedule I Indian Wild Life Protection Act 1972), are rampant in India. Between January 2011 and March 2017, around 550 peafowl in 35 incidences were reported dead across the country. Due to the non-availability of fresh carcases, poisoning could not be confirmed. Birds which died due to kite string injuries in Ahmedabad (15) and accidents in Coimbatore (5) were tested for residues of chlorinated pesticides, namely hexachlorocyclohexane (HCH), dichloro-diphenyl-trichloroethane (DDT), endosulfan, heptachlor, dicofol, dieldrin and cholipyrifos...
March 23, 2018: Environmental Science and Pollution Research International
Omar Thiaw, Souleymane Doucouré, Seynabou Sougoufara, Charles Bouganali, Lassana Konaté, Nafissatou Diagne, Ousmane Faye, Cheikh Sokhna
BACKGROUND: The use of insecticides, through indoor residual spraying and long-lasting insecticide-treated nets (LLINs), is essential to control malaria vectors. However, the sustainability of these tools is challenged by the spread of insecticide resistance in Anopheles mosquitoes. This study was conducted to assess the susceptibility to insecticides and to determine the resistance mechanisms in malaria vectors in Dielmo, a rural area of western Senegal where LLINs were introduced a decade ago...
March 22, 2018: Malaria Journal
Satoshi Nobusako, Ayami Sakai, Taeko Tsujimoto, Takashi Shuto, Yuki Nishi, Daiki Asano, Emi Furukawa, Takuro Zama, Michihiro Osumi, Sotaro Shimada, Shu Morioka, Akio Nakai
The neurological basis of developmental coordination disorder (DCD) is thought to be deficits in the internal model and mirror-neuron system (MNS) in the parietal lobe and cerebellum. However, it is not clear if the visuo-motor temporal integration in the internal model and automatic-imitation function in the MNS differs between children with DCD and those with typical development (TD). The current study aimed to investigate these differences. Using the manual dexterity test of the Movement Assessment Battery for Children (second edition), the participants were either assigned to the probable DCD (pDCD) group or TD group...
2018: Frontiers in Neurology
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"