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https://www.readbyqxmd.com/read/29239502/insecticide-susceptibility-status-of-invasive-aedes-albopictus-across-dengue-endemic-districts-of-odisha-india
#1
Animesha Rath, Ipsita Mohanty, Rupenangshu K Hazra
BACKGROUND: Aedes albopictus is currently the most invasive mosquito species in the world. Keeping in view the wide emergence of insecticide resistance, it is imperative to focus on the current susceptibility status for various insecticides in Ae. albopictus. The present study is focused on understanding the insecticide resistance mechanism of Ae. albopictus collected from dengue endemic districts of Odisha. RESULTS: Insecticide resistance was evaluated by using standardized bioassay kits (WHO) and biochemical analysis...
December 14, 2017: Pest Management Science
https://www.readbyqxmd.com/read/29215751/proteomic-response-of-the-rat-liver-in-differential-swimming-modes
#2
Liang Chen, Yanhua Yang, Yiting Wang, Lipeng Qiu, Hengchuan Xia, Aiai Wang, Hailong Liu, Hongfei Shi, Keping Chen
Moderate exercise helps improve competition results, providing a balanced muscle tone and biochemical activity, whereas excessive training disrupts the balance between training and recovery, causes harm to the organism, and leads to overtraining syndrome (OTS). To explore the mechanisms of different protein expressions during training and acquisition of immunity, we used proteomic analyses to investigate the differences of liver-protein expressions between two swimming modes. Sprague-Dawley rats were randomly divided into control (CT), fatigue training (FT), and exhaustive training (ET) groups, and liver tissues from each group were subjected to two-dimensional electrophoresis (2DE)...
December 7, 2017: Clinical and Experimental Pharmacology & Physiology
https://www.readbyqxmd.com/read/29213072/characterization-of-large-copy-number-variation-in-mexican-type-2-diabetes-subjects
#3
Iván de Jesús Ascencio-Montiel, Dalila Pinto, Esteban J Parra, Adán Valladares-Salgado, Miguel Cruz, Stephen W Scherer
The effect of Copy Number Variants (CNVs) on Type 2 Diabetes (T2D) remains little explored. The present study characterized large rare CNVs in 686 T2D and 194 non-T2D subjects of Mexican ancestry genotyped using the Affymetrix Genome-Wide Human SNP array 5.0. Rare CNVs with ≥ 100 kb length were identified using a stringent strategy based on merging CNVs calls generated using Birdsuit, iPattern and PennCNV algorithms. We applied three different strategies to evaluate the distribution of CNVs in the T2D and non-T2D samples: 1) Burden analysis, 2) Identification of CNVs in loci previously associated to T2D, and 3) Identification of CNVs observed only in the T2D group...
December 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29211847/changes-in-neuronal-signaling-and-cell-stress-response-pathways-are-associated-with-a-multigenic-response-of-drosophila-melanogaster-to-ddt-selection
#4
Keon Mook Seong, Brad S Coates, Weilin Sun, John M Clark, Barry R Pittendrigh
The adaptation of insect populations to insecticidal control is a continual threat to human health and sustainable agricultural practices, but many complex genomic mechanisms involved in this adaption remain poorly understood. This study applied a systems approach to investigate the interconnections between structural and functional variance in response to dichlorodiphenyltrichloroethane (DDT) within the Drosophila melanogaster strain 91-R. Directional selection in six selective sweeps coincided with constitutive gene expression differences in DDT resistant flies, including the most highly up-regulated transcript, Unc-115b, which plays a central role in axon guidance, and the most highly down-regulated transcript, the angiopoietin-like CG31832, which is involved in directing vascular branching and dendrite outgrowth but likely under trans-regulatory control...
December 1, 2017: Genome Biology and Evolution
https://www.readbyqxmd.com/read/29210611/tracking-residual-organochlorine-pesticides-ocps-in-green-herbal-and-black-tea-leaves-and-infusions-of-commercially-available-tea-products-marketed-in-poland
#5
Agata Witczak, Hassan Abdel-Gawad, Michal Zalesak, Anna Pohoryło
The content of residual organochlorine pesticides (OCPs) was examined in green, herbal, and black tea leaves as well as in their infusions prepared from tea products marketed in the main supermarkets in Poland. It was found that the detected mean levels of organochlorine residues in tea leaves ranged from <LOD to 16.36 ng g-1 dry weight. Among HCH isomers γ-HCH in green tea occurred in the highest concentrations. Of DDT metabolites the highest level of pp'DDT (1.96 ng g-1 dw) was in green tea samples. The transfer of OCPs from tea leaves to brew was investigated...
December 6, 2017: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/29209805/selected-persistent-organic-pollutants-pops-in-water-of-river-niger-occurrence-and-distribution
#6
J P Unyimadu, O Osibanjo, J O Babayemi
This study assessed the levels and distribution of selected persistent organic pollutants (POPs) in water of River Niger. The selected POPs of interest were organochlorine pesticides (OCPs). Fifteen representative sites along River Niger: three each from Gurara River (tributary) in Niger State, Lokoja (confluence) in Kogi State, Onitsha in Anambra State, Brass and Nicolas Rivers (tributaries) in Bayelsa State were selected for sampling quarterly over a 24-month period. A total of 240 surface and bottom water samples were collected using Van Dorn water sampler in the eight quarters of 2008-2009...
December 6, 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29179640/2-4-dinitroanisole-dnan-2014
#7
(no author information available yet)
2,4-dinitroanisole (DNAN) is a warhead explosive currently under investigation as a replacement for TNT in melt-cast insensitive munitions. In animal studies, DNAN is a mild ocular and skin irritant with a significant potential for dermal absorption.  It is not a dermal sensitizer.  Acute and subacute rat inhalation studies demonstrated minimal toxicity with LC50 and LOAEL endpoints of 2.9 and 150 mg/m3, respectively.  In rat oral toxicity studies (14 and 90 days) organ weight and clinical chemistry changes suggested hepatocellular injury and anemia, particularly in females...
January 1, 2017: Toxicology and Industrial Health
https://www.readbyqxmd.com/read/29156266/seabirds-as-regional-biomonitors-of-legacy-toxicants-on-an-urbanized-coastline
#8
Corey A Clatterbuck, Rebecca L Lewison, Nathan G Dodder, Catherine Zeeman, Kenneth Schiff
Seabirds are often cited as sentinels of the marine environment, but are rarely used in traditional ocean and coastal contaminant monitoring. Four classes of persistent organic pollutants (POPs, n=68) and three trace elements (mercury, selenium, and arsenic) were measured in the eggs of California least terns (Sterna antillarum browni), caspian terns (Hydroprogne caspia), double-crested cormorants (Phalacrocorax auritus), and western gulls (Larus occidentalis) that nest in the Southern California Bight. Building on a periodic five year regional monitoring program, we measured contaminant exposure and assessed the utility of seabirds as regional contaminant biomonitors...
November 16, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29154179/the-effect-of-follicullar-fluid-pesticides-and-polychlorinated-biphenyls-concentrations-on-intracytoplasmic-sperm-injection-icsi-embryological-and-clinical-outcome
#9
Tarek K Al-Hussaini, Ahmed A Abdelaleem, Ihab Elnashar, Omar M Shabaan, Rashad Mostafa, Mona A H El-Baz, Sahar E M El-Deek, Tarek A Farghaly
OBJECTIVES: The present study evaluated the correlation between the concentrations of polychlorinated biphenyls (PCBs) and pesticides in the follicular fluid (FF) obtained during intracytoplasmic sperm injection (ICSI) with the ovarian response, endometrial thickness, and embryological and clinical outcomes. DESIGN: Cross-sectional observational study. MATERIALS AND METHODS: Women aged 20 to 38 years (300 infertile couples) presenting to a university-affiliated fertility center were approached to participate in the study...
November 15, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29153728/role-of-black-carbon-in-soil-distribution-of-organochlorines-in-lesser-himalayan-region-of-pakistan
#10
Usman Ali, Rahat Riaz, Andrew James Sweetman, Kevin C Jones, Jun Li, Gan Zhang, Riffat Naseem Malik
Black carbon and total organic carbon (TOC) along with organochlorines (OCs) were analyzed in soils from four sampling zones of Lesser Himalayan Region based on source proximity/anthropogenic influences along the altitude. CTO-375 method was used for BC analysis while OCs were analyzed by GC-MS/MS system. BC and TOC ranged between 0.16-1.77 and 6.8-41.3 mg g(-1) while those of OCPs and PCBs ranged between 0.69 and 5.77 and 0.12-2.55 ng g(-1), respectively. ∑DDTs were the dominant (87.9%) among OCPs while tri- and tetra- (65...
November 16, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29151024/insecticide-resistance-in-anopheles-arabiensis-from-ethiopia-2012-2016-a-nationwide-study-for-insecticide-resistance-monitoring
#11
Louisa A Messenger, Josephat Shililu, Seth R Irish, Gedeon Yohannes Anshebo, Alemayehu Getachew Tesfaye, Yemane Ye-Ebiyo, Sheleme Chibsa, Dereje Dengela, Gunawardena Dissanayake, Estifanos Kebede, Endalew Zemene, Abebe Asale, Mekonnen Yohannes, Hiwot Solomon Taffese, Kristen George, Christen Fornadel, Aklilu Seyoum, Robert A Wirtz, Delenasaw Yewhalaw
BACKGROUND: Indoor residual spraying (IRS) and long-lasting insecticidal nets (LLINs) remain the cornerstones of malaria vector control. However, the development of insecticide resistance and its implications for operational failure of preventative strategies are of concern. The aim of this study was to characterize insecticide resistance among Anopheles arabiensis populations in Ethiopia and describe temporal and spatial patterns of resistance between 2012 and 2016. METHODS: Between 2012 and 2016, resistance status of An...
November 18, 2017: Malaria Journal
https://www.readbyqxmd.com/read/29148584/metabolic-effects-of-p-p-dde-on-atlantic-salmon-hepatocytes
#12
Pål A Olsvik, Liv Søfteland
Decades after being banned in many countries, DDT and its metabolites are still considered major environmental hazards. The p,p'-DDE isomer, the DDT metabolite found in highest concentration in aquaculture feeds, is an endocrine disruptor with demonstrated ability to induce epigenetic effects. This study aimed at examining the impact of p,p'-DDE on Atlantic salmon. Primary hepatocytes were exposed to four concentrations of p,p'-DDE (0.1, 1, 10, 100 μm) for 48 hours, and endpoints included cytotoxicity, global DNA methylation, targeted transcription and metabolomics profiling (100 μm)...
November 17, 2017: Journal of Applied Toxicology: JAT
https://www.readbyqxmd.com/read/29136593/polycyclic-aromatic-hydrocarbons-and-organochlorine-pesticides-in-surface-water-from-the-yongding-river-basin-china-seasonal-distribution-source-apportionment-and-potential-risk-assessment
#13
Yizhen Wang, Shilu Zhang, Wenyan Cui, Xianzhi Meng, Xianqiang Tang
The presence of 17 polycyclic aromatic hydrocarbons (PAHs) and 15 persistent organochlorine pesticides (OCPs) in surface water of the Yongding River Basin was analyzed through GC/MS/MS during the spring and summer at 46 sampling sites. The goal was to investigate their seasonal distribution, possible sources, and potential risk. Our results showed that the total PAH concentration in surface water of Yongding River Basin ranged from 41.60 to 1482.60ng/L with a mean value of 137.85ng/L in the spring, and from 53...
November 11, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29135968/body-burden-of-dichlorodiphenyl-dichloroethene-dde-and-childhood-pulmonary-function
#14
Pallavi P Balte, Joachim Kühr, Herrman Kruse, Wilfried J J Karmaus
Longitudinal studies have shown that early life exposure to dichlorodiphenyl dichloroethene (DDE) can lead to growth reduction during childhood and adolescence. In addition, DDE exposure has been linked to respiratory tract infections and an increased risk of asthma in children. Our aim was to understand the relationships between DDE exposure and pulmonary function in children, and, particularly, whether associations are mediated by the height of the children. We used data from an environmental epidemiologic study conducted in central Germany in children aged 8-10 years...
November 14, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29131997/organochlorine-pesticides-across-the-tributaries-of-river-ravi-pakistan-human-health-risk-assessment-through-dermal-exposure-ecological-risks-source-fingerprints-and-spatio-temporal-distribution
#15
Mujtaba Baqar, Yumna Sadef, Sajid Rashid Ahmad, Adeel Mahmood, Jun Li, Gan Zhang
This study monitored the human health risks through dermal exposure, hazardous risks to ecological integrity, contamination levels, spatio-temporal distribution, and congener specific analysis of organochlorine pesticides (OCPs) across River Ravi and its three northern tributaries (Nullah Bein, Nullah Basanter and Nullah Deg). The residual levels of OCPs isomers were screened for water (n=54) and surface sediment (n=54) samples from twenty seven sampling sites in two alternate seasons (pre-monsoon and post-monsoon)...
November 10, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29126515/endocrine-disruptors-eds-and-hormone-dependent-cancers-correlation-or-causal-relationship
#16
Henri Rochefort
The selective increase in the incidence of hormone-dependent cancers (breast, prostate, testicular) in industrialized countries is associated with the increasing number of endocrine disruptors (EDs) in the environment and raises questions about the role of EDs in mammary carcinogenesis. Answering these questions is difficult because the number of EDs is large and varies with time. Moreover hormonal carcinogenesis is multifactorial and progresses slowly and in stages. This discussion will be limited to breast cancer and three EDs: distilbene, bisphenol A (BPA), and dichlorodiphenyltrichloroethane (DDT)...
September 2017: Comptes Rendus Biologies
https://www.readbyqxmd.com/read/29115954/malaria-vectors-in-the-democratic-republic-of-the-congo-the-mechanisms-that-confer-insecticide-resistance-in-anopheles-gambiae-and-anopheles-funestus
#17
Luisa Nardini, Richard H Hunt, Yael L Dahan-Moss, Nanette Christie, Riann N Christian, Maureen Coetzee, Lizette L Koekemoer
BACKGROUND: The Democratic Republic of the Congo (DRC) is characterized as a holoendemic malaria area with the main vectors being Anopheles funestus and members of the Anopheles gambiae complex. Due to political instability and socio-economic challenges in the region, knowledge of insecticide resistance status and resistance mechanisms in these vectors is limited. Mosquitoes were collected from a mining site in the north-eastern part of the country and, following identification, were subjected to extensive testing for the target-site and biochemical basis of resistance...
November 7, 2017: Malaria Journal
https://www.readbyqxmd.com/read/29107582/perinatal-exposure-to-endocrine-disrupting-compounds-and-the-control-of-feeding-behavior-an-overview
#18
REVIEW
Sabrina N Walley, Troy A Roepke
Endocrine disrupting compounds (EDC) are ubiquitous environmental contaminants that can interact with steroid and nuclear receptors or alter hormone production. Many studies have reported that perinatal exposure to EDC including bisphenol A, PCB, dioxins, and DDT disrupt energy balance, body weight, adiposity, or glucose homeostasis in rodent offspring. However, little information exists on the effects of perinatal EDC exposure on the control of feeding behaviors and meal pattern (size, frequency, duration), which may contribute to their obesogenic properties...
November 7, 2017: Hormones and Behavior
https://www.readbyqxmd.com/read/29100182/transplacental-transfer-characteristics-of-organochlorine-pesticides-in-paired-maternal-and-cord-sera-and-placentas-and-possible-influencing-factors
#19
Xiaolan Zhang, Xia Wu, Bingli Lei, Ye Jing, Zi'an Jiang, Xinyu Zhang, Xiangming Fang, Yingxin Yu
Organochlorine pesticides (OCPs), including dichlorodiphenyltrichloroethane (DDT) and its metabolites [dichlorodiphenyldichloroethylene (DDE) and dichlorodiphenyldichloroethane], hexachlorocyclohexanes (HCHs), and hexachlorobenzene (HCB), are widely detected in humans despite the considerable decline in environmental concentrations. To understand the placental transfer of OCPs and the possible maternal influence on them, we measured the concentrations of DDTs, HCHs, and HCB in 102 paired samples of maternal and cord sera, and placentas collected in Shanghai, China...
October 31, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29099469/biomonitoring-of-metals-polybrominated-diphenyl-ethers-polychlorinated-biphenyls-persistent-pesticides-in-vietnamese-female-electronic-waste-recyclers
#20
Arnold Schecter, Jenevieve Kincaid, Hoang Trong Quynh, Joel Lanceta, Hanh Thi Tuyet Tran, Riley Crandall, William Shropshire, Linda S Birnbaum
OBJECTIVE: Electronic-waste is increasing.Its frequently conducted in developing countries.This is the first study to report metals, polybrominated diphenyl-ethers(PBDEs), polychlorinated biphenyls(PCBs), 2,2-bis(4-chlorophenyl)-1,1,1-trichloroethane(p,p'-DDT), and p,p'-DDE concentrations in female e-waste workers. METHODS: Female Vietnamese recyclers and non-recyclers were studied. Metals and halogenated organics were measured in blood and urine, and compared to levels in women in the US National Health and Nutrition Examination Survey(NHANES)...
November 2, 2017: Journal of Occupational and Environmental Medicine
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