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https://www.readbyqxmd.com/read/28097496/historical-trends-of-organochlorine-pesticides-ocps-recorded-in-sediments-across-the-tibetan-plateau
#1
Ruiqiang Yang, Ting Xie, Handong Yang, Simon Turner, Guangjian Wu
Sediment cores from four lakes across the Tibetan Plateau were used as natural archives to study the time trends of organochlorine pesticides (OCPs). The total concentrations of dichlorodiphenyltrichloroethane (ΣDDT) and hexachlorocyclohexane isomers (ΣHCH) were in the range of 0.04-1.61 and 0.08-1.88 ng/g based on dry weight (dw), while the input fluxes were in the range of 0.3-236 and 0.7-295 pg/cm(2)/y in the core sediments, respectively. The input fluxes of ΣDDT and ΣHCH generally peaked in sediment layers corresponding to the 1970s-1990s and peaked in top sediment layers...
January 17, 2017: Environmental Geochemistry and Health
https://www.readbyqxmd.com/read/28093672/influence-of-quechers-modifications-on-recovery-and-matrix-effect-during-the-multi-residue-pesticide-analysis-in-soil-by-gc-ms-ms-and-gc-ecd-npd
#2
Bożena Łozowicka, Ewa Rutkowska, Magdalena Jankowska
A QuEChERS extraction followed by GC/MS/MS and GC-μECD/NPD for 216 pesticide and metabolites determination in soil simultaneously were developed and compared. Volume of water, volume and polarity of solvent, and cleanup sorbents (C18, GCB, PSA) were optimized. The QuEChERS with and without purification step were applied to estimate effectiveness of the method. The recovery and matrix effect (ME) were critical parameters within each tested procedure. The optimal method without cleanup was validated. Accuracy (expressed as recovery), precision (expressed as RSD), linearity, LOQ, and uncertainty were determined...
January 16, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28089717/persistent-organic-pollutants-pops-in-human-follicular-fluid-and-in-vitro-fertilization-outcomes-a-pilot-study
#3
Michael S Bloom, Victor Y Fujimoto, Robin Storm, Li Zhang, Celeste D Butts, Diana Sollohub, Robert L Jansing
Persistent organic pollutants (POPs) are ubiquitously distributed among the U.S. population and adversely impact human reproduction. These compounds have been detected in human ovarian follicular fluid (FF), where they directly contact a developing oocyte. As a pilot investigation, we measured 43 polychlorinated biphenyl (PCB) congeners, p,p'-dichlorodiphenyltrichloroethane (DDT), and its persistent metabolite p,p'-dichlorodiphenyldichloroethylene (DDE) in residual FF collected from 32 women undergoing in vitro fertilization (IVF)...
January 9, 2017: Reproductive Toxicology
https://www.readbyqxmd.com/read/28088046/application-of-acid-modified-polyurethane-foam-surface-for-detection-and-removing-of-organochlorine-pesticides-from-wastewater
#4
E A Moawed, A M Radwan
The commercial polyurethane foam was acid modified to get an inexpensive adsorbent (AM-PUF) has highly surface polarity and sorption capacity. The elemental analysis, scanning electron microscopy, thermal analysis, ultraviolet/visible/infrared spectroscopies and X-ray diffraction were used for characterization of AM-PUF. The surface of AM-PUF has amorphous character (broadband at 2θ, 21.75°) and contains several active sites e.g. NH, OH, CO, CC and COC groups. The electrical conductivity (σ), iodine value and methylene blue index of AM-PUF are 1...
January 7, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28086840/evidence-of-multiple-insecticide-resistance-mechanisms-in-anopheles-gambiae-populations-in-bangui-central-african-republic
#5
Marina Lidwine Olé Sangba, Aboubakar Sidick, Renaud Govoetchan, Christian Dide-Agossou, Razaki A Ossè, Martin Akogbeto, Mamadou Ousmane Ndiath
BACKGROUND: Knowledge of insecticide resistance status in the main malaria vectors is an essential component of effective malaria vector control. This study presents the first evaluation of the status of insecticide resistance in Anopheles gambiae populations from Bangui, the Central African Republic. METHODS: Anopheles mosquitoes were reared from larvae collected in seven districts of Bangui between September to November 2014. The World Health Organisation's bioassay susceptibility tests to lambda-cyhalothrin (0...
January 13, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28069371/distribution-and-enantiomeric-profiles-of-organochlorine-pesticides-in-surface-sediments-from-the-bering-sea-chukchi-sea-and-adjacent-arctic-areas
#6
Meiqing Jin, Jie Fu, Bin Xue, Shanshan Zhou, Lina Zhang, An Li
The spatial distribution, compositional profiles, and enantiomer fractions (EFs) of organochlorine pesticides (OCPs), including hexachlorocyclohexanes (HCHs), dichlorodiphenyltrichloroethanes (DDTs), and chlordanes (CHLs), in the surface sediments in the Bering Sea, Chukchi Sea and adjacent areas were investigated. The total concentrations of DDTs, HCHs and CHLs varied from 0.64 to 3.17 ng/g dw, 0.19-0.65 ng/g dw, and 0.03-0.16 ng/g dw, respectively. No significant difference was observed between the Bering Sea and Chukchi Sea for most pollutants except for trans-CHL, ΣCHLs (sum of trans- and cis-chlordane) and p,p'-DDD...
January 6, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28069368/polychlorinated-dibenzo-p-dioxins-dibenzofurans-and-flame-retardants-in-northern-gannet-morus-bassanus-eggs-from-bonaventure-island-gulf-of-st-lawrence-1994-2014
#7
Louise Champoux, Jean-François Rail, Raphael A Lavoie
Northern gannet (Morus bassanus) eggs from Bonaventure Island, Québec, Canada, were collected to monitor concentrations of contaminants. Polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDDs/Fs) and non-ortho polychlorinated biphenyls (PCBs) were measured in eggs from 2004 and 2009, and several brominated and nonbrominated flame retardants (FRs) were measured every 2-5 years in eggs from 1994 to 2014. The sum (Σ) concentrations of PCDDs/Fs were significantly lower in 2009 relative to 2004, but the total toxic equivalent concentrations for PCDDs, PCDFs, and PCBs showed no significant differences (196 ng/kg wet weight (ww) in 2004 and 220 ng/kg ww in 2009)...
January 6, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28065571/exposure-to-ddt-and-diabetic-nephropathy-among-mexican-americans-in-the-1999-2004-national-health-and-nutrition-examination-survey
#8
Charles J Everett, Olivia M Thompson, Clara E Dismuke
Concentrations of the pesticide DDT (dichlorodiphenyltrichloroethane) and its metabolite DDE (dichlorodiphenyldichloroethylene), in the blood of Mexican Americans, were evaluated to determine their relationships with diabetes and diabetic nephropathy. The data were derived from the National Health and Nutrition Examination Survey (NHANES) 1999-2004 (unweighted N = 1,411, population estimate = 13,760,609). The sample included teens, 12-19 years old, which accounted for 19.8% of the data. The time of the study overlapped the banning of DDT in Mexico in the year 2000, and those participants born in Mexico were exposed to DDT before they immigrated to the US...
January 5, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28055195/non-targeted-screening-of-halogenated-organic-compounds-in-bottlenose-dolphins-tursiops-truncatus-from-rio-de-janeiro-brazil
#9
Mariana B Alonso, Keith A Maruya, Nathan Gray Dodder, José Lailson-Brito, Alexandre Freitas Azevedo, Elitieri Santos-Neto, João Paulo Machado Torres, Olaf Malm, Eunha Hoh
To catalog the diversity and abundance of halogenated organic compounds (HOCs) accumulating in high trophic marine species from the southwestern Atlantic Ocean, tissue from bottlenose dolphins (Tursiops truncatus) stranded or incidentally captured along the coast of Rio de Janeiro, Brazil, were analyzed by a non-targeted approach based on GC×GC/TOF-MS. A total of 158 individual HOCs from 32 different structural classes were detected in the blubber of 4 adult male T. truncatus. Nearly 90 percent of the detected compounds are not routinely monitored in the environment...
January 5, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28054908/binaural-interference-and-the-effects-of-age-and-hearing-loss
#10
Bruna S S Mussoi, Ruth A Bentler
BACKGROUND: The existence of binaural interference, defined here as poorer speech recognition with both ears than with the better ear alone, is well documented. Studies have suggested that its prevalence may be higher in the elderly population. However, no study to date has explored binaural interference in groups of younger and older adults in conditions that favor binaural processing (i.e., in spatially separated noise). Also, the effects of hearing loss have not been studied. PURPOSE: To examine binaural interference through speech perception tests, in groups of younger adults with normal hearing, older adults with normal hearing for their age, and older adults with hearing loss...
January 2017: Journal of the American Academy of Audiology
https://www.readbyqxmd.com/read/28053074/promoting-adoption-of-the-3rs-through-regulatory-qualification
#11
Elizabeth Gribble Walker, Amanda F Baker, John-Michael Sauer
One mechanism to advance the application of novel safety assessment methodologies in drug development, including in silico or in vitro approaches that reduce the use of animals in toxicology studies, is regulatory qualification. Regulatory qualification, a formal process defined at the the U. S. Food and Drug Administration and the European Medicines Agency, hinges on a central concept of stating an appropriate "context of use" for a novel drug development tool (DDT) that precisely defines how that DDT can be used to support decision making in a regulated drug development setting...
December 2016: ILAR Journal
https://www.readbyqxmd.com/read/28043072/association-of-serum-organochlorine-pesticides-concentrations-with-reproductive-hormone-levels-and-polycystic-ovary-syndrome-in-a-chinese-population
#12
Zhizhun Guo, Huiling Qiu, Lingling Wang, Lijun Wang, Chonggang Wang, Meng Chen, Zhenghong Zuo
To investigate the serum concentrations of organochlorine pesticides (OCPs) in patients with polycystic ovary syndrome (PCOS), a total of 178 women were studied. The concentrations of hexachlorocyclohexane (HCH) and dichlorodiphenyltrichloroethane (DDT) in serum were determined using Gas Chromatography Mass-Mass Spectrometer. No differences with statistical significance in the mean HCH, p,p'-DDD, p,p'-DDE concentrations were observed between the patients with PCOS and the control group. Serum p,p'-DDT (P = 0...
December 26, 2016: Chemosphere
https://www.readbyqxmd.com/read/28032101/current-susceptibility-status-of-anopheles-stephensi-diptera-culicidae-to-different-imagicides-in-a-malarious-area-southeastern-of-iran
#13
Mohammad Amin Gorouhi, Hassan Vatandoost, Mohammad Ali Oshaghi, Ahmad Raeisi, Ahmad Ali Enayati, Hossein Mirhendi, Ahmad Ali Hanafi-Bojd, Mohammad Reza Abai, Yaser Salim-Abadi, Fatemeh Rafi
BACKGROUND: Anopheles mosquitoes are an important group of arthropods due to their role in transmission of malaria. The present study was conducted for determination of susceptibility status of Anopheles stephensi to different imagicides collected from malarious area in Chabahar city, Iran. METHODS: In the present study seven insecticides including: DDT 4%, lambdacyhalothrin 0.05%, deltamethrin 0.05%, permethrin 0.75%, cyfluthrin 0.15% and etofenprox 0.5% were tested based on WHO method...
December 2016: Journal of Arthropod-borne Diseases
https://www.readbyqxmd.com/read/28032100/high-insecticides-resistance-in-culex-pipiens-diptera-culicidae-from-tehran-capital-of-iran
#14
Yaser Salim-Abadi, Mohammad Ali Oshaghi, Ahmad Ali Enayati, Mohammad Reza Abai, Hassan Vatandoost, Mohammad Reza Eshraghian, Hossein Mirhendi, Ahmad Ali Hanafi-Bojd, Mohammad Amin Gorouhi, Fatemeh Rafi
BACKGROUND: During recent years transmission of Dirofilaria immitis (dog heart worm) by Culex pipiens and West Nile virus have been reported from Iran. The present study was preformed for evaluating the susceptibility status of Cx. pipiens collected from capital city of Tehran, Iran. METHODS: Four Insecticides including: DDT 4%, Lambdacyhalothrin 0.05%, Deltamethrin 0.05% and Cyfluthrin 0.15 % according to WHO standard methods were used for evaluating the susceptibility status of Cx...
December 2016: Journal of Arthropod-borne Diseases
https://www.readbyqxmd.com/read/28025743/relationship-between-organochlorine-pesticides-and-stress-indicators-in-hawksbill-sea-turtle-eretmochelys-imbricata-nesting-at-punta-xen-campeche-southern-gulf-of-mexico
#15
Nelly Tremblay, Alejandro Ortíz Arana, Mauricio González Jáuregui, Jaime Rendón-von Osten
Data on the impact of environmental pollution on the homeostasis of sea turtles remains scarce, particularly in the Southern Gulf of Mexico. As many municipalities along the coastline of the Yucatan Peninsula do not rely on a waste treatment plant, these organisms could be particularly vulnerable. We searched for relationships between the presence of organochlorine pesticides (OCP) and the level of several oxidative and pollutant stress indicators of the hawksbill sea turtle (Eretmochelys imbricata) during the 2010 nesting season at Punta Xen (Campeche, Mexico)...
December 26, 2016: Ecotoxicology
https://www.readbyqxmd.com/read/28024448/effects-of-pentachlorophenol-and-dichlorodiphenyltrichloroethane-on-secretion-of-interferon-gamma-ifn%C3%AE-and-tumor-necrosis-factor-alpha-tnf%C3%AE-from-human-immune-cells
#16
Reda Massawe, Leon Drabo, Margaret Whalen
Pentachlorophenol (PCP) and dichlorodiphenyltrichloroethane (DDT) are pesticides that have been widely used and significantly contaminate the environment. Both are found in human blood and have been shown to alter the lytic and binding function of human natural killer (NK) cells. Interferon gamma (IFNγ) and tumor necrosis factor alpha (TNFα) are pro-inflammatory cytokines which regulate immune responsiveness to pathogens and tumors. Their levels require very tight control to prevent loss of immune competence or excessive inflammation...
December 26, 2016: Toxicology Mechanisms and Methods
https://www.readbyqxmd.com/read/28011991/hair-analysis-for-the-biomonitoring-of-pesticide-exposure-comparison-with-blood-and-urine-in-a-rat-model
#17
Brice M R Appenzeller, Emilie M Hardy, Nathalie Grova, Caroline Chata, François Faÿs, Olivier Briand, Henri Schroeder, Radu-Corneliu Duca
Urine and plasma have been used to date for the biomonitoring of exposure to pollutants and are still the preferred fluids for this purpose; however, these fluids mainly provide information on the short term and may present a high level of variability regarding pesticide concentrations, especially for nonpersistent compounds. Hair analysis may provide information about chronic exposure that is averaged over several months; therefore, this method has been proposed as an alternative to solely relying on these fluids...
December 23, 2016: Archives of Toxicology
https://www.readbyqxmd.com/read/28011686/a-survey-of-insecticide-resistance-in-aedes-albopictus-diptera-culicidae-during-a-2014-dengue-fever-outbreak-in-guangzhou-china
#18
Wang Yiguan, Liu Xin, Li Chengling, Tianyun Su, Jin Jianchao, Guo Yuhong, Ren Dongsheng, Yang Zhicong, Liu Qiyong, Meng Fengxia
A dengue fever outbreak in Guangzhou, Guangdong Province, China, in 2014 resulted in ∼37,000 cases and five deaths. Insecticides were sprayed to control the vector of this outbreak, Aedes albopictus (Skuse), a species of mosquito. Aedes albopictus specimens collected from Huadu District (HD), Huangpu District (HP), Luogang District (LG), and Nansha District (NS) in Guangzhou were evaluated using WHO-recommended bioassays for both larvae and adult mosquitoes to determine population resistance to deltamethrin, beta-cypermethrin, cypermethrin, permethrin, dichlorvos, temephos, propoxur, and DDT...
December 23, 2016: Journal of Economic Entomology
https://www.readbyqxmd.com/read/28007452/evaluation-of-hazardous-chemicals-in-edible-insects-and-insect-based-food-intended-for-human-consumption
#19
Giulia Poma, Matthias Cuykx, Elvio Amato, Chiara Calaprice, Jean Francois Focant, Adrian Covaci
Due to the rapid increase in world population, the waste of food and resources, and non-sustainable food production practices, the use of alternative food sources is currently strongly promoted. In this perspective, insects may represent a valuable alternative to main animal food sources due to their nutritional value and sustainable production. However, edible insects may be perceived as an unappealing food source and are indeed rarely consumed in developed countries. The food safety of edible insects can thus contribute to the process of acceptance of insects as an alternative food source, changing the perception of developed countries regarding entomophagy...
December 19, 2016: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/27993108/molecular-mechanism-of-action-and-selectivity-of-sodium-channel-blocker-insecticides
#20
Kristopher Silver, Ke Dong, Boris S Zhorov
Sodium channel blocker insecticides (SCBIs) are a relatively new class of insecticides that are represented by two commercially registered compounds, indoxacarb and metaflumizone. SCBIs, like pyrethroids and DDT, target voltage-gated sodium channels (VGSCs) to intoxicate insects. In contrast to pyrethroids, however, SCBIs inhibit VGSCs at a distinct receptor site that overlaps those of therapeutic inhibitors of sodium channels, such as local anesthetics, anticonvulsants and antiarrhythmics. This review will recount the development of the SCBI insecticide class from its roots as chitin synthesis inhibitors, discuss the symptoms of poisoning and evidence supporting inhibition of VGSCs as their mechanism of action, describe the current model for SCBI-induced inhibition of VGSCs, present a model for the receptor for SCBIs on VGSCs, and highlight differences between data collected from mammalian and insect experimental models...
December 16, 2016: Current Medicinal Chemistry
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