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https://www.readbyqxmd.com/read/28437004/4-4-dichlorodiphenyltrichloroethane-ddt-and-4-4-dichlorodiphenyldichloroethylene-dde-inhibit-myogenesis-in-c2c12-myoblasts
#1
Jonggun Kim, Min Young Park, Yoo Kim, Kyong Sup Yoon, John Marshall Clark, Yeonhwa Park, Kwang-Youn Whang
BACKGROUND: Most countries have banned the use of 4,4'-Dichlorodiphenyltrichloroethane (DDT). However, due to its extremely high lipophilic characteristics, DDT and its metabolite 4,4'-dichlorodiphenyldichloroethylene (DDE) are ubiquitous in the environment and in many types of food. The positive correlation between exposure to insecticides, including DDT and DDE, and weight gain, resulting in impaired energy metabolism in offspring following perinatal DDT and DDE exposure was previously reported...
April 24, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28434213/evaluation-of-the-synergistic-effect-of-mixed-cultures-of-white-rot-fungus-pleurotus-ostreatus-and-biosurfactant-producing-bacteria-on-ddt-biodegradation
#2
Adi Setyo Purnomo, Khoirul Ashari, Farizha Triyogi Hermansyah
DDT (1,1,1-trichloro-2,2-bis(4-chlorophenyl) ethane) is one of the organic synthetic pesticides that has many negative effects for human health and the environment. The purpose of this study was to investigate the synergistic effect of mixed cutures of white-rot fungus, Pleurotus ostreatus, and biosurfactant-producing bacteria, Pseudomonas aeruginosa and Bacillus subtilis, on DDT biodegradation. Bacteria was added into P. ostreatus culture (mycelial wet weight on average by 8.53 g) in concentrations of 1, 3, 5, and 10 mL (1 mL ≈ 1...
April 21, 2017: Journal of Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28434068/assessment-of-ddt-and-metabolites-in-soil-and-sediment-of-potentially-contaminated-areas-of-bel%C3%A3-m-amazon-region-brazil
#3
Andreia Oliveira Rodrigues, Larissa Costa de Souza, Cássia Christina da Silva Rocha, Amilton Cesar Gomes da Costa, Rosivaldo de Alcântara Mendes
The aim of this study was to evaluate the distribution of DDT and metabolites in surface soils and soil profiles from two areas containing deposits of obsolete pesticides in Belém, Amazon Region, Brazil. DDT and metabolites were extracted by microwave assisted extraction and analyzed by gas chromatography with electron capture detection. Concentrations of total DDT in surface soil samples ranged from 64.22 mg kg(-1) in area 1 (A1) to 447.84 mg kg(-1) in area 2 (A2). Lower levels were found in soil profiles than at the surface (6...
April 22, 2017: Bulletin of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28432879/seasonal-variation-and-health-risk-assessment-of-organochlorine-compounds-in-urban-soils-of-novi-sad-serbia
#4
Biljana D Škrbić, Vesna Marinković, Igor Antić, Anita Petrović Gegić
The aim of this paper was to determine spatial and seasonal variation of 6 indicator polychlorinated biphenyls (PCBs) and 18 organochlorine pesticides (OCPs) in urban soils of Novi Sad, Serbia. Sixty surface soil samples were collected during both winter and summer season, from different types of locations: schools, recreational areas, residential and industrial zones. Samples were treated using the method of accelerated solvent extraction, which allows simultaneous extraction and clean up of PCBs and OCPs...
April 15, 2017: Chemosphere
https://www.readbyqxmd.com/read/28421252/altitude-distributions-and-source-analysis-of-ocps-and-pcbs-in-surface-soils-of-changbai-mountain-northeast-china
#5
Xiaochun Wang, Shu Chen, Kuiyuan Wan, Xiaocai Yin, Xiaohua Zhu, Jing Pan, Yongliang Yang
Organochlorine pesticides and polychlorinated biphenyls in surface soils of Changbai Mountain, Northeastern China, have been quantified by gas chromatography with electron capture detector and the altitude distributions and possible pollution sources were analyzed. The concentrations of ∑HCHs, ∑DDTs and ∑7PCBs were in the range of 3.09-25.6, 0.96-19.4 and 7.32-26.1 ng/g dw, respectively. The concentration of α-HCH, β-HCH, p,p'-DDT, p,p'-DDE, PCB 101, 138, 153, and 180 showed increasing trends with altitude...
April 18, 2017: Bulletin of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28397872/organochloride-pesticides-impaired-mitochondrial-function-in-hepatocytes-and-aggravated-disorders-of-fatty-acid-metabolism
#6
Qian Liu, Qihan Wang, Cheng Xu, Wentao Shao, Chunlan Zhang, Hui Liu, Zhaoyan Jiang, Aihua Gu
p,p'-dichlorodiphenyldichloroethylene (p, p'-DDE) and β-hexachlorocyclohexane (β-HCH) were two predominant organochlorine pesticides (OCPs) metabolites in human body associated with disorders of fatty acid metabolism. However, the underlying mechanisms have not been fully clarified. In this study, adult male C57BL/6 mice were exposed to low dose of p, p'-DDE and β-HCH for 8 wk. OCPs accumulation in organs, hepatic fatty acid composition, tricarboxylic acid cycle (TCA) metabolites and other metabolite profiles were analyzed...
April 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28395858/association-between-exposure-to-organochlorine-compounds-and-maternal-thyroid-status-role-of-the-iodothyronine-deiodinase-1-gene
#7
Sabrina Llop, Mario Murcia, Mar Alvarez-Pedrerol, Joan O Grimalt, Loreto Santa-Marina, Jordi Julvez, Fernando Goñi-Irigoyen, Mercedes Espada, Ferran Ballester, Marisa Rebagliato, Maria-Jose Lopez-Espinosa
INTRODUCTION: Exposure to organochlorine compounds (OCs) may interfere with thyroid hormone (TH) homeostasis. The disruption of the deiodinase (DIO) enzymes has been proposed as a mechanism of action. AIM: To evaluate the association between exposure to OCs and TH status in pregnant women, as well as to explore the role of genetic variations in the DIO1 and DIO2 genes. METHODS: The study population (n=1128) was composed of pregnant women who participated in the INMA Project (Spain, 2003-2006)...
April 8, 2017: Environment International
https://www.readbyqxmd.com/read/28392238/organochloride-pesticides-modulated-gut-microbiota-and-influenced-bile-acid-metabolism-in-mice
#8
Qian Liu, Wentao Shao, Chunlan Zhang, Cheng Xu, Qihan Wang, Hui Liu, Haidong Sun, Zhaoyan Jiang, Aihua Gu
Organochlorine pesticides (OCPs) can persistently accumulate in body and threaten human health. Bile acids and intestinal microbial metabolism have emerged as important signaling molecules in the host. However, knowledge on which intestinal microbiota and bile acids are modified by OCPs remains unclear. In this study, adult male C57BL/6 mice were exposed to p, p'-dichlorodiphenyldichloroethylene (p, p'-DDE) and β-hexachlorocyclohexane (β-HCH) for 8 weeks. The relative abundance and composition of various bacterial species were analyzed by 16S rRNA gene sequencing...
April 6, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28391837/continuous-fraction-collection-of-gas-chromatographic-separations-with-parallel-mass-spectrometric-detection-applied-to-cell-based-bioactivity-analysis
#9
Willem Jonker, Jan B Stöckl, Sjaak de Koning, Jaap Schaap, Govert W Somsen, Jeroen Kool
We describe the development and evaluation of a GC-MS fractionation platform that combines high-resolution fraction collection of full chromatograms with parallel MS detection. A y-split at the column divides the effluent towards the MS detector and towards an inverted y-piece where vaporized trap solvent is infused. The latter flow is directed outside the GC oven allowing subsequent condensation and stepwise collection of liquid fractions with trapped analytes on a 384-well plate. For study and optimization of the effluent split ratio, restriction capillaries of different lengths and diameters were evaluated...
June 1, 2017: Talanta
https://www.readbyqxmd.com/read/28386194/effect-of-aerobic-exercise-intervention-on-ddt-degradation-and-oxidative-stress-in-rats
#10
Kefeng Li, Xiaohua Zhu, Yuzhan Wang, Shuqian Zheng, Guijun Dong
Dichlorodiphenyltrichloroethane (DDT) reportedly causes extensively acute or chronic effects to human health. Exercise can generate positive stress. We evaluated the effect of aerobic exercise on DDT degradation and oxidative stress. MAIN METHODS: Male Wistar rats were randomly assigned into control (C), DDT without exercise training (D), and DDT plus exercise training (DE) groups. The rats were treated as follows: DDT exposure to D and DE groups at the first 2 weeks; aerobic exercise treatment only to the DE group from the 1st day until the rats are killed...
March 2017: Saudi Journal of Biological Sciences
https://www.readbyqxmd.com/read/28384585/polyhalogenated-compounds-chlorinated-paraffins-novel-and-classic-flame-retardants-pops-in-dishcloths-after-their-regular-use-in-households
#11
Christoph Gallistl, Bianca Lok, Annika Schlienz, Walter Vetter
Dishcloths are routinely used in the clean-up process following daily kitchen activities and are thus subject to contamination commensurate with their frequent use. Here we analyzed dishcloths for the occurrence of polyhalogenated compounds after 14days of use in household kitchens. Analysis of 19 dishcloths revealed the presence of 29 polyhalogenated contaminants with total mean/median concentrations of 6,900/3,600ng/dishcloth, respectively. The spectrum featured classic and novel halogenated flame-retardants (HFRs) like polybrominated diphenyl ethers (PBDEs), hexabromocyclododecane (HBCD), decabromodiphenyl ethane (DBDPE), pentabromoethylbenzene (PBEB), chlordene plus and dechlorane plus, as well as typical chloropesticides and background contaminants (e...
April 3, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28382465/significance-of-genetic-variations-in-developmental-enamel-defects-of-primary-dentition-in-polish-children
#12
Karolina Gerreth, Katarzyna Zaorska, Maciej Zabel, Michal Nowicki, Maria Borysewicz-Lewicka
OBJECTIVES: The aim of the study was to reveal the association between developmental defects of enamel (DDE) and single nucleotide polymorphisms (SNPs) in the ENAM, AMELX, AMBN, TUFT1, and TFIP11 genes. MATERIAL AND METHODS: The molecular analysis was carried out in 52 children, aged 10-42 months, from four nursery schools situated in the region of Poznan, Poland (26 individuals with hypomineralization and/or hypoplasia of enamel - "cases" and 26 unaffected children - "controls"), chosen from 262 individuals that had prior dental examination...
April 5, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28372942/human-biomonitoring-reference-values-derived-for-persistent-organic-pollutants-in-blood-plasma-from-the-canadian-health-measures-survey-2007-2011
#13
Douglas A Haines, Cheryl Khoury, Gurusankar Saravanabhavan, Kate Werry, Mike Walker, Morie Malowany
Nationally representative human biomonitoring data on persistent organic pollutants (POPs) including organochlorine pesticides (OCs), polychlorinated biphenyls (PCBs) brominated flame retardants (BFRs) and perfluoroalkyl substances (PFASs) are available through the Canadian Health Measures Survey (CHMS). We have used a systematic approach building on the reference interval concept proposed by the International Federation of Clinical Chemistry and Laboratory Medicine and the International Union of Pure and Applied Chemistry to derive human biomonitoring reference values (RV95s) for selected POPs in blood plasma in the general Canadian population...
March 18, 2017: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/28355053/experimental-study-on-the-role-of-sedimentation-and-degradation-processes-on-atmospheric-deposition-of-persistent-organic-pollutants-in-a-subtropical-water-column
#14
Yumei Huang, Ruijie Zhang, Kechang Li, Zhineng Cheng, Guangcai Zhong, Gan Zhang, Jun Li
The goal of this study is to experimentally assess the role of vertical sinking and degradation processes of persistent organic pollutants (POPs) in a subtropical water column. This was done by measuring the concentrations of selected typical organochlorine pesticides, including hexachlorocyclohexanes (HCHs), hexachlorobenzene (HCB), dichlorodiphenyltrichloroethanes (DDTs), trans-chlordane (TC), and cis-chlordane (CC), in atmosphere (gas phase), water (dissolved and particulate phases), and sedimentation samples simultaneously from October 2011 to April 2013 in a subtropical lake...
April 7, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28349741/organochlorine-pesticides-ocps-in-raft-mussels-coming-from-galician-r%C3%A3-as
#15
Nieves Carro, Isabel García, María Ignacio, Ana Mouteira
This survey gives an overview of the range of organochlorine pesticides (OCPs) α and γ-HCH (lindane), HCB, pp´-DDE, pp´-DDD, op´-DDT, pp´-DDT, aldrin, dieldrin, endrin, isodrin and trans-nonachlor in raft mussels cultivated in several polygons of the Galician Rías (Ares-Betanzos, Muros-Noia, Arousa, Pontevedra and Vigo) during the period 1998-2014. A significant number of OCPs were detected but the levels found were generally low, mainly in the recent samplings (2010-2014). The levels of ∑DDs (sum of DDTs and its metabolites, pp´-DDE and pp´-DDD) ranged between 0...
March 28, 2017: Food Additives & Contaminants. Part B, Surveillance
https://www.readbyqxmd.com/read/28342592/polychlorinated-biphenyls-pcbs-and-organochlorine-pesticides-ocps-in-sediments-from-an-urban-and-industrial-impacted-subtropical-estuary-babitonga-bay-brazil
#16
Juliane Rizzi, Satie Taniguchi, César C Martins
Babitonga Bay is a large estuary, which has been under pressure from anthropogenic activities coexisting with a natural area of Atlantic rainforest and mangrove systems. The concentration of persistent organic pollutants (POPs), such as polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs) was determined to evaluate the contamination status and the determine possible pollution sources in the estuary. The ∑DDT (sum of DDT, DDE and DDD concentrations) was the predominant OCP group, with concentrations ranging from <DL (below detection limit) to 122ng g(-1)...
March 23, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28328072/tensor-estimation-for-double-pulsed-diffusional-kurtosis-imaging
#17
Calvin B Shaw, Edward S Hui, Joseph A Helpern, Jens H Jensen
Double-pulsed diffusional kurtosis imaging (DP-DKI) represents the double diffusion encoding (DDE) MRI signal in terms of six-dimensional (6D) diffusion and kurtosis tensors. Here a method for estimating these tensors from experimental data is described. A standard numerical algorithm for tensor estimation from conventional (i.e. single diffusion encoding) diffusional kurtosis imaging (DKI) data is generalized to DP-DKI. This algorithm is based on a weighted least squares (WLS) fit of the signal model to the data combined with constraints designed to minimize unphysical parameter estimates...
March 22, 2017: NMR in Biomedicine
https://www.readbyqxmd.com/read/28327259/prevalence-of-enamel-developmental-defects-and-relationship-with-early-childhood-caries-in-trinidad
#18
Rahul S Naidu, June H Nunn
PURPOSE: The purpose of this study was to describe the prevalence of developmental defects of enamel (DDE) and their relationship with early childhood caries (ECC) among preschool children in Trinidad. METHODS: A cross-sectional oral health survey of 251 three- to five-year-old preschool children was undertaken in central Trinidad. The decayed, missing, and filled primary teeth (dmft) index and the DDE index were used to measure visible caries experience and enamel developmental defects, respectively...
September 15, 2016: Journal of Dentistry for Children
https://www.readbyqxmd.com/read/28320527/characterization-and-genome-functional-analysis-of-the-ddt-degrading-bacterium-ochrobactrum-sp-ddt-2
#19
Xiong Pan, Tianheng Xu, Haoyu Xu, Hua Fang, Yunlong Yu
A strain of Ochrobactrum sp. DDT-2 that was capable of degrading DDT as the sole carbon and energy source was isolated and sequenced, and its biodegradation characteristics and metabolism mechanism were examined. The genome sequence of the isolate DDT-2 was composed of 4,630,303bp with a GC content of 55.99% and 4454 coding genes. The degradation rate of DDT by the isolate DDT-2 increased with the increasing substrate concentration (0.1-10mg/l) and temperature (20-40°C). The degradation half-life of DDT in the presence of the isolate DDT-2 at pH7...
March 17, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28314123/which-persistent-organic-pollutants-in-the-rivers-of-the-bohai-region-of-china-represent-the-greatest-risk-to-the-local-ecosystem
#20
Yueqing Zhang, Andrew C Johnson, Chao Su, Meng Zhang, Monika D Jürgens, Yajuan Shi, Yonglong Lu
Freshwater aquatic organisms can be exposed to hundreds of persistent organic pollutants (POPs) discharged by natural and anthropogenic activities. Given our limited resources it is necessary to identify, from the existing evidence, which is the greatest threat so that control measures can be targeted wisely. The focus of this study was to rank POPs according to the relative risk they represent for aquatic organisms in rivers in the Bohai Region, China. A list of 14 POPs was compiled based on the available data on their presence in these rivers and ecotoxicological data...
February 28, 2017: Chemosphere
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