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https://www.readbyqxmd.com/read/28654338/small-intracranial-aneurysms-diagnostic-accuracy-of-ct-angiography
#1
Zhen Lu Yang, Qian Qian Ni, U Joseph Schoepf, Carlo N De Cecco, Han Lin, Taylor M Duguay, Chang Sheng Zhou, Yan E Zhao, Guang Ming Lu, Long Jiang Zhang
Purpose To assess the accuracy of computed tomographic (CT) angiography for diagnosis of cerebral aneurysms 5 mm or smaller, with digital subtraction angiography (DSA) as the reference standard, in a large patient cohort Materials and Methods This retrospective study was approved by the local institutional review board with a waiver of written informed consent. A total of 1366 patients who underwent cerebral CT angiography followed by DSA were included. The performance of CT angiography for depiction of aneurysms was evaluated by two readers on a per-patient and per-aneurysm basis and based on size of aneurysm, location, and status of rupture...
June 26, 2017: Radiology
https://www.readbyqxmd.com/read/28653646/early-predictors-of-outcome-after-mild-traumatic-brain-injury-upfront-an-observational-cohort-study
#2
Joukje van der Naalt, Marieke E Timmerman, Myrthe E de Koning, Harm J van der Horn, Myrthe E Scheenen, Bram Jacobs, Gerard Hageman, Tansel Yilmaz, Gerwin Roks, Jacoba M Spikman
BACKGROUND: Mild traumatic brain injury (mTBI) accounts for most cases of TBI, and many patients show incomplete long-term functional recovery. We aimed to create a prognostic model for functional outcome by combining demographics, injury severity, and psychological factors to identify patients at risk for incomplete recovery at 6 months. In particular, we investigated additional indicators of emotional distress and coping style at 2 weeks above early predictors measured at the emergency department...
July 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28652286/point-of-care-ultrasound-versus-ct-pulmonary-angiogram-in-suspected-pulmonary-embolus
#3
Joseph Bacani Bacani, Kerstin De Wit
A short cut review was carried out to establish whether non-invasive, multi-organ point of care ultrasound could reduce the need for CTPA in adult patients presenting with clinical suspicion of pulmonary embolus. 3 papers presented the best evidence to answer the clinical question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these papers are tabulated. It is concluded that multi-organ POCUS shows promise but that more data is needed to make a definitive statement regarding validity in clinical practice...
July 2017: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/28650885/aggressive-imaging-features-in-a-malignant-pheochromocytoma-with-a-novel-mutation-of-the-sdhb-gene
#4
Soon-Ah Park, Dae Ho Lee, Hun Soo Kim
We describe a 15-year-old boy with a huge bilateral adrenal pheochromocytoma that had a de novo germline mutation in the succinate dehydrogenase subunit B (SDHB) gene. F-FDG PET/CT revealed bilateral metabolically active large masses in the adrenal glands and the activated brown adipose tissues. The I-MIBG scintigraphic findings revealed only a mild accumulation of MIBG in the right adrenal mass, but a high uptake in the left adrenal mass. Thus, F-FDG PET/CT imaging may be more effective than I-MIBG scintigraphy for the evaluation of pheochromocytomas that are associated with highly malignant characteristics resulting from mutations of the SDHB gene...
June 24, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28650083/additional-value-of-b-flow-imaging-in-arterial-wall-calcifications
#5
Fabrizio D'Abate, Jorg L de Bruin
The accuracy of color Doppler ultrasonography (CDU) is hampered by the presence of arterial wall calcifications. B-flow imaging may overcome these limitations. We present a case of a severely calcified stenosis of the right common femoral artery (CFA) diagnosed with the aid of B-flow imaging. Both the CT angiography scan and CDU were limited by the presence of diffuse dense arterial calcifications. B-flow imaging showed a >75% stenosis of the CFA. B-flow imaging appears to improve the accuracy of CDU in the presence of calcified stenosis of the CFA...
June 26, 2017: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/28649954/in-vitro-validation-of-coronary-ct-angiography-for-the-evaluation-of-complex-lesions
#6
Carlos Collet, Yoshinobu Onuma, Maik J Grundeken, Yosuke Miyazaki, Marcio Bittercourt, Pieter Kitslaar, Sadako Motoyama, Yukio Ozaki, Taku Asano, Jolanda J Wentzel, Geert J Streekstra, Patrick W Serruys, Robbert J de Winter, Nihls Planken
AIMS: To assess in vitro the diagnostic accuracy of computed tomography angiography (CTA) for the evaluation of complex coronary lesions. METHODS AND RESULTS: Five Plexiglas phantoms with three bifurcations lesions each were designed to mimic the anatomic variations and fractal phenomenon of the coronary tree. In addition, luminal stenosis were scaled up with increases of 10%. A third generation dual-source computed tomography was used. Automated quantitative CTA analysis was performed...
June 27, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28649708/potential-benefits-of-crawl-position-for-prone-radiation-therapy-in-breast-cancer
#7
Bert Boute, Wilfried De Neve, Bruno Speleers, Annick Van Greveling, Christel Monten, Tom Van Hoof, Joris Van de Velde, Leen Paelinck, Werner De Gersem, Tom Vercauteren, Jan Detand, Liv Veldeman
PURPOSE: To investigate crawl position with the arm at the treated side alongside the body and at the opposite side above the head for prone treatment in patients requiring breast and regional lymph node irradiation. METHODS: Patient support devices for crawl position were built for CT simulation and treatment. An asymmetric fork design resulted from an iterative process of prototype construction and testing. The fork's large horn supports the hemi-thorax, shoulder, and elevated arm at the nontreated side and the head...
June 26, 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28649158/implementation-of-material-decomposition-using-an-emccd-and-cmos-based-micro-ct-system
#8
Alexander R Podgorsak, Sv Setlur Nagesh, Daniel R Bednarek, Stephen Rudin, Ciprian N Ionita
This project assessed the effectiveness of using two different detectors to obtain dual-energy (DE) micro-CT data for the carrying out of material decomposition. A micro-CT coupled to either a complementary metal-oxide semiconductor (CMOS) or an electron multiplying CCD (EMCCD) detector was used to acquire image data of a 3D-printed phantom with channels filled with different materials. At any instance, materials such as iohexol contrast agent, water, and platinum were selected to make up the scanned object...
February 11, 2017: Proceedings of SPIE
https://www.readbyqxmd.com/read/28646594/prevalence-and-prognosis-of-low-volume-oligorecurrent-hormone-sensitive-prostate-cancer-amenable-to-lesion-ablative-therapy
#9
Aurélie De Bruycker, Bieke Lambert, Tom Claeys, Louke Delrue, Chamberlain Mbah, Gert De Meerleer, Geert Villeirs, Filip De Vos, Kathia De Man, Karel Decaestecker, Valérie Fonteyne, Nicolaas Lumen, Filip Ameye, Ignace Billiet, Steven Joniau, Friedl Vanhaverbeke, Wim Duthoy, Piet Ost
OBJECTIVES: To describe the anatomical patterns of PCa recurrence following primary therapy and investigate if patients with low-volume disease have a better prognosis as compared to their counterparts. MATERIAL AND METHODS: Patients eligible for a F18-choline PET-CT were entered in a prospective cohort study. Eligible patients had an asymptomatic biochemical recurrence following primary PCa treatment and testosterone levels >50 ng/ml. The number of lesions were counted per scan...
June 24, 2017: BJU International
https://www.readbyqxmd.com/read/28645684/detection-and-quantification-of-223-ra-uptake-in-bone-metastases-of-patients-with-castration-resistant-prostate-carcinoma-with-the-aim-of-determining-the-absorbed-dose-in-the-metastases
#10
P Mínguez, A Gómez de Iturriaga, I L Fernández, E Rodeño
PURPOSES: To obtain the necessary acquisition and calibration parameters in order to evaluate the possibility of detecting and quantifying (223)Ra uptake in bone metastases of patients treated for castration resistant prostate carcinoma. Furthermore, in the cases in which the activity can be quantified, to determine the absorbed dose. MATERIAL AND METHODS: Acquisitions from a Petri dish filled with (223)Ra were performed in the gamma camera. Monte Carlo simulations were also performed to study the partial volume effect...
June 20, 2017: Revista Española de Medicina Nuclear e Imagen Molecular
https://www.readbyqxmd.com/read/28644774/cd33-splicing-polymorphism-determines-gemtuzumab-ozogamicin-response-in-de-novo-acute-myeloid-leukemia-report-from-randomized-phase-iii-children-s-oncology-group-trial-aaml0531
#11
Jatinder K Lamba, Lata Chauhan, Miyoung Shin, Michael R Loken, Jessica A Pollard, Yi-Cheng Wang, Rhonda E Ries, Richard Aplenc, Betsy A Hirsch, Susana C Raimondi, Roland B Walter, Irwin D Bernstein, Alan S Gamis, Todd A Alonzo, Soheil Meshinchi
Purpose Gemtuzumab ozogamicin (GO), a CD33-targeted immunoconjugate, is a re-emerging therapy for acute myeloid leukemia (AML). CD33 single nucleotide polymorphism rs12459419 C>T in the splice enhancer region regulates the expression of an alternatively spliced CD33 isoform lacking exon2 (D2-CD33), thus eliminating the CD33 IgV domain, which is the antibody-binding site for GO, as well as diagnostic immunophenotypic panels. We aimed to determine the impact of the genotype of this splicing polymorphism in patients with AML treated with GO-containing chemotherapy...
June 23, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28644571/difference-between-respiratory-epithelial-adenomatoid-hamartomas-and-small-malignant-tumors-of-the-olfactory-cleft-on-ct-scans-in-forty-six-patients
#12
Théophile De Saint Hilaire, Cécile Rumeau, Patrice Gallet, Phi-Linh Nguyen-Thi, Roger Jankowski, Duc Trung Nguyen
Misdiagnosis of respiratory epithelial adenomatoid hamartomas for malignant tumors can lead to an aggressive surgical procedure, which is not necessary in the case of a respiratory epithelial adenomatoid hamartoma. Detailed analysis of sinonasal CT scans without contrast can help to distinguish respiratory epithelial adenomatoid hamartomas of the olfactory cleft from small malignant tumors (T1 and T2) of the olfactory clefts. Criteria in favor of diagnosis of small malignant tumors of the olfactory clefts on CT scans without contrast were unilaterality of masses in the olfactory clefts, large olfactory clefts /small olfactory clefts ratio ≥ 2 (sensibility at 91% and specificity at 100%), and presence of bone erosion...
June 23, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28643076/scintigraphic-peritoneography-reveals-a-non-uniform-99m-tc-pertechnetat-aerosol-distribution-pattern-for-pressurized-intra-peritoneal-aerosol-chemotherapy-pipac-in-a-swine-model
#13
Alexander Bellendorf, Veria Khosrawipour, Tanja Khosrawipour, Simon Siebigteroth, Joseph Cohnen, David Diaz-Carballo, Andreas Bockisch, Jürgen Zieren, Urs Giger-Pabst
BACKGROUND: Although recent data are contradictory, it is still claimed that Pressurized Intra-Peritoneal Aerosol Chemotherapy (PIPAC) would deliver an aerosol which distributes homogeneously throughout the entire abdominal cavity. METHODS: (99m)Tc-Pertechnetat was administered in four postmortem swine using either PIPAC or liquid intra-peritoneal chemotherapy (IPC). The animals were examined by planar scintigraphy and SPECT/CT. Planar distribution images were divided into four regions of interest (ROIs: right/left upper and lower abdominal quadrant)...
June 22, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28642648/morphological-analysis-of-the-scapula-and-its-implications-in-bristow-latarjet-procedure
#14
Joana Daniela DE Oliveira Silva, Catarina Neves Damas, Márcia Christel DE Carvalho Sá, João Manuel Costa Ferreira Torres
OBJECTIVE: To assess which of two procedures, Bristow or Latarjet, is anatomically the most appropriate for the general population . METHODS: One thousand one hundred and thirty two shoulders were evaluated by an observer who measured the following coracoid process parameters - length, angle and minimum thickness - through Computed Tomography (CT) analysis. Statistical analysis was carried out by ANOVA and Bland-Altman tests . RESULTS: The mean length, angle and minimum thickness of the coracoid were 27...
January 2017: Acta Ortopedica Brasileira
https://www.readbyqxmd.com/read/28642643/tomographic-morphological-study-of-the-cranium-and-its-correlation-with-cranial-halo-use-in-adults
#15
Tiago Ferreira DE Almeida, Homar Toledo Charafeddine, Fernando Flores DE Araújo, Alexandre Fogaça Cristante, Raphael Martus Marcon, Olavo Biraghi Letaif
OBJECTIVE: To evaluate using tomographic study the thickness of the cranial board at the insertions points of the cranial halo pins in adults. METHODS: This is a retrospective, cross-sectional, descriptive analysis of Computed Tomography (CT) scans of adult patients' crania. The study included adults between 20 and 50 years without cranial abnormalities. We excluded any exam with cranial abnormalities. RESULTS: We analyzed 50 CT scans, including 27 men and 23 women, at the original insertion points and alternative points (1 and 2 cm above the frontal and parietal bones)...
January 2017: Acta Ortopedica Brasileira
https://www.readbyqxmd.com/read/28640320/molecular-signature-of-coronary-stent-thrombosis-oxidative-stress-and-innate-immunity-cells
#16
Judit Cubedo, Ana Blasco, Teresa Padro, Ilaria Ramaiola, Oriol Juan-Babot, Javier Goicolea, José Antonio Fernández-Díaz, Juan Francisco Oteo, Lina Badimon
The clinical impact of in-stent thrombosis is high because it is associated with high mortality and 20 % of the patients suffer a recurrent event within the two following years. The aim of this study was to characterise the morphologic and proteomic profile of in-stent thrombi (IST) in comparison to thrombi developed on native coronary arteries (CT) to identify a differential molecular signature. The study included 45 patients with ST-elevation-myocardial-infarction (STEMI) treated by primary-percutaneous-intervention and thrombus aspiration: 21 had IST and 24 had CT...
June 22, 2017: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/28639458/use-of-computed-tomography-to-define-a-sacral-safe-corridor-for-placement-of-2-7-mm-cortical-screws-in-feline-sacroiliac-luxation
#17
Helen Philp, Alexane Durand, Felipe De Vicente
Objectives This study aimed to define a safe corridor for 2.7 mm cortical sacroiliac screw insertion in the dorsal plane (craniocaudal direction) using radiography and CT, and in the transverse plane (dorsoventral direction) using CT in feline cadavers. A further aim was to compare the values obtained by CT with those previously reported by radiography in the transverse plane. Methods Thirteen pelvises were retrieved from feline cadavers and dissected to expose one of the articular surfaces of the sacrum. A 2...
June 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28631339/the-length-of-the-large-intestine-in-children-determined-by-ct-scan
#18
Ali Mirjalili, Gregory Tarr, Mark Stringer
Little information is available on the length of the normal large intestine and its component parts in children. This information would be useful for procedures such as colonoscopy. The aim of this study was to investigate the length of the large intestine and its component parts in New Zealand children. Archival de-identified pediatric supine abdominopelvic computed tomography (CT) scans were retrospectively analyzed. After exclusion criteria, a total of 112 scans (57 males and 55 females) were included in the study and divided into three age groups: 0-2 years (n=33), 4-6 years (n=40), and 9-11 years of age (n=39)...
June 20, 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/28631088/etiologies-diagnostic-work-up-and-outcomes-of-acute-respiratory-distress-syndrome-with-no-common-risk-factor-a-prospective-multicenter-study
#19
Nicolas de Prost, Tài Pham, Guillaume Carteaux, Armand Mekontso Dessap, Christian Brun-Buisson, Eddy Fan, Giacomo Bellani, John Laffey, Alain Mercat, Laurent Brochard, Bernard Maître
BACKGROUND: Patients meeting the Berlin definition for the acute respiratory distress syndrome (ARDS) might lack exposure to one or more "common" risk factors and exhibit different clinical phenotype and outcomes. We aimed to compare the clinical presentation and outcome of ARDS patients with or without risk factors, the impact on hospital mortality, and to assess the diagnostic work-up performed. The current study is an ancillary analysis of an international, multicenter, prospective cohort study (the Large Observational Study to Understand the Global Impact of Severe Acute Respiratory Failure, LUNG SAFE)...
December 2017: Annals of Intensive Care
https://www.readbyqxmd.com/read/28629942/can-a-target-zone-safer-than-lewinnek-s-safe-zone-be-defined-to-prevent-instability-of-total-hip-arthroplasties-case-control-study-of-56-dislocated-tha-and-93-matched-controls
#20
N Reina, S Putman, R Desmarchelier, E Sari Ali, P Chiron, M Ollivier, J Y Jenny, D Waast, C Mabit, E de Thomasson, C Schwartz, P Oger, L E Gayet, H Migaud, N Ramdane, M H Fessy
BACKGROUND: Various factors contribute to instability of total hip arthroplasty (THA), with implant orientation being a major contributor. We performed a case-control study with computed tomography (CT) data to determine whether 1) orientation contributes to THA instability and 2) a safer target zone for stability than Lewinnek's classic safe zone can be defined. MATERIAL AND METHODS: We included prospectively 363 cases of THA dislocation that occurred during the calendar 2013 year in 24 participating hospitals...
June 16, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
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