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https://www.readbyqxmd.com/read/29350644/talar-fractures-radiological-and-ct-evaluation-and-classification-systems
#1
Giuseppe Caracchini, Michele Pietragalla, Alioscia De Renzis, Michele Galluzzo, Mattia Carbone, Marcello Zappia, Anna Russo, Federico Greco, Vittorio Miele
INTRODUCTION: The talus is the second largest bone of the foot. It is fundamental to ensure normal ankle-foot movements as it connects the leg and the foot. Talar fractures are usually due to high energy traumas (road accidents, high level falls). They are not common as they account for 3-5% of ankle and foot fractures and 0.85% of all body fractures. However, talar fractures not correctly diagnosed and treated can lead to avascular necrosis of the astragalus, pseudoarthrosis, early osteoarthrisis and ankle instability, declining the quality of life of patients...
January 19, 2018: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29350643/calcaneal-fractures-radiological-and-ct-evaluation-and-classification-systems
#2
Michele Galluzzo, Federico Greco, Michele Pietragalla, Alioscia De Renzis, Mattia Carbone, Marcello Zappia, Nicola Maggialetti, Alfredo D'andrea, Giuseppe Caracchini, Vittorio Miele
BACKGROUND AND AIM OF THE WORK: The calcaneus, the more lower bone of the body, has the task of supporting the axial load from the weight of the body. Calcaneal fractures represent about 1-2% of all fractures and 60% of the tarsal bones fractures. The articular involvement has been associated with a poor functional outcome. The aim of this work is to describe the radiologic evaluation, the classification systems, the morphological preoperative diagnostic imaging features of calcaneal fractures, highlighting the correlation with the choice of treatment and predictive capacity for the fracture surgical outcome...
January 19, 2018: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29348868/luminal-like-her2-negative-stage-ia-breast-cancer-a-multicenter-retrospective-study-on-long-term-outcome-with-propensity-score-analysis
#3
Carmine De Angelis, Massimo Di Maio, Anna Crispo, Mario Giuliano, Francesco Schettini, Marta Bonotto, Lorenzo Gerratana, Donatella Iacono, Marika Cinausero, Ferdinando Riccardi, Giuseppe Ciancia, Michelino De Laurentiis, Fabio Puglisi, Sabino De Placido, Grazia Arpino
The benefit of adding chemotherapy (CT) to adjuvant hormone therapy (HT) in stage IA luminal-like HER2-negative breast cancer (BC) is unclear. We retrospectively evaluated predictive factors and clinical outcome of 1,222 patients from 4 oncologic centers. Three hundred and eighty patients received CT and HT (CT-cohort) and 842 received HT alone (HT-cohort). Disease-free survival (DFS) and overall survival (OS) were evaluated with univariate and multivariate analyses. We also applied the propensity score methodology...
December 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/29348301/predicting-the-presence-of-macrovascular-causes-in-non-traumatic-intracerebral-haemorrhage-the-diagram-prediction-score
#4
Nina A Hilkens, Charlotte J J van Asch, David J Werring, Duncan Wilson, Gabriël J E Rinkel, Ale Algra, Birgitta K Velthuis, Gérard A P de Kort, Theo D Witkamp, Koen M van Nieuwenhuizen, Frank-Erik de Leeuw, Wouter J Schonewille, Paul L M de Kort, Diederik W J Dippel, Theodora W M Raaymakers, Jeannette Hofmeijer, Marieke J H Wermer, Henk Kerkhoff, Korné Jellema, Irene M Bronner, Michel J M Remmers, Henri Paul Bienfait, Ron J G M Witjes, H Rolf Jäger, Jacoba P Greving, Catharina J M Klijn
OBJECTIVE: A substantial part of non-traumatic intracerebral haemorrhages (ICH) arises from a macrovascular cause, but there is little guidance on selection of patients for additional diagnostic work-up. We aimed to develop and externally validate a model for predicting the probability of a macrovascular cause in patients with non-traumatic ICH. METHODS: The DIagnostic AngioGRAphy to find vascular Malformations (DIAGRAM) study (n=298; 69 macrovascular cause; 23%) is a prospective, multicentre study assessing yield and accuracy of CT angiography (CTA), MRI/ magnetic resonance angiography (MRA) and intra-arterial catheter angiography in diagnosing macrovascular causes in patients with non-traumatic ICH...
January 18, 2018: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29346056/esophageal-leiomyoma-in-a-dog-causing-esophageal-distension-and-treated-by-transcardial-placement-of-a-self-expanding-covered-nitinol-esophageal-stent
#5
Elisabeth M Robin, Pascaline B Pey, Pauline de Fornel-Thibaud, Pierre H M Moissonnier, Valérie Freiche
CASE DESCRIPTION A 10-year-old spayed female Rottweiler was referred for evaluation because of a 2-month history of regurgitation and weight loss, despite no apparent change in appetite. The dog had received antiemetic and antacid treatment, without improvement. CLINICAL FINDINGS Physical examination revealed a low body condition score (2/5), but other findings were unremarkable. Diffuse, global esophageal dilatation was noted on plain thoracic radiographs, and normal motility was confirmed through videofluoroscopic evaluation of swallowing...
February 1, 2018: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/29345517/pet-adapted-therapy-for-advanced-hodgkin-lymphoma-systematic-review
#6
Irina Amitai, Ronit Gurion, Liat Vidal, Eldad J Dann, Pia Raanani, Anat Gafter-Gvili
INTRODUCTION: Positron emission tomography-computed tomography (PET-CT) performed after two chemotherapy cycles (PET-2) has become an accepted prognostic tool in Hodgkin lymphoma (HL). We evaluated the effect of PET-adapted strategy on outcome in advanced stage HL. METHODS: In August 2017, we searched electronic databases, conference proceedings and ongoing trials. We included all studies in which treatment modification for advanced HL was performed based on the results of the interim PET scan...
January 18, 2018: Acta Oncologica
https://www.readbyqxmd.com/read/29342055/benefit-of-preoperative-temporal-bone-ct-for-atraumatic-cochlear-implantation
#7
Alexandre Karkas, Nicolas Menjot de Champfleur, Alain Uziel, Michel Mondain, Jean-Luc Puel, Frédéric Venail
HYPOTHESIS: Evaluate the benefit of preoperative surgical planning using computed tomography (CT) for atraumatic cochlear implantation. BACKGROUND: The surgical technique has a direct impact on hearing and structure preservation. Much interest has been given to depth of electrode insertion. We focused on electrode diameter depending on exposure of round window membrane (RWM) as calculated on preoperative CT. METHODS: Measurements were calculated radiologically and anatomically on 10 temporal bones...
January 16, 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29340610/preclinical-18f-tetrafluoroborate-pet-ct-imaging-of-pituitary-gland-hyperplasia
#8
Marcin Balcerzyk, Laura Fernandez-Maza, Juan Jose Mínguez, Manuel De-Miguel
No abstract text is available yet for this article.
January 11, 2018: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29338912/-surgical-outcomes-of-traumatic-cervical-fractures-in-patients-with-ankylosing-spondylitis
#9
Alberto Isla Guerrero, Beatriz Mansilla Fernández, Borja Hernández Garcia, Álvaro Gómez de la Riva, María Luisa Gandía González, Elena Isla Paredes
OBJECTIVE: Ankylosing spondylitis is an inflammatory rheumatic disease mainly affecting the axial skeleton. The rigid spine may secondarily develop osteoporosis, further increasing the risk of spinal fracture. In this study, we reviewed fractures in patients with ankylosing spondylitis that had been clinically diagnosed to better define the mechanism of injury, associated neurological deficit, predisposing factors, and management strategies. METHODS: Between January 2004 and December 2014, 6 patients with ankylosing spondylitis and neurological complications after injuries were treated...
January 12, 2018: Neurocirugía
https://www.readbyqxmd.com/read/29337433/numerical-simulation-of-two-consecutive-nasal-respiratory-cycles-toward-a-better-understanding-of-nasal-physiology
#10
Ludovic de Gabory, Nicolas Reville, Yannick Baux, Nicolas Boisson, Laurence Bordenave
BACKGROUND: Computational fluid dynamic (CFD) simulations have greatly improved the understanding of nasal physiology. We postulate that simulating the entire and repeated respiratory nasal cycles, within the whole sinonasal cavities, is mandatory to gather more accurate observations and better understand airflow patterns. METHODS: A 3-dimensional (3D) sinonasal model was constructed from a healthy adult computed tomography (CT) scan which discretized in 6.6 million cells (mean volume, 0...
January 16, 2018: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29335909/persistent-posterior-seroma-after-laparoscopic-repair-of-ventral-abdominal-wall-hernias-with-expanded-polytetrafluoroethylene-mesh-prevalence-independent-predictors-and-detached-tacks-retrospective-review
#11
V M A Stirler, R J de Haas, J T F J Raymakers, S Rakic
PURPOSE: A persistent seroma located posterior to a mesh (PPS) remains a little known complication after laparoscopic ventral hernia repair (LVHR). The aim of this large case series was to analyse the prevalence and clinical course as well as identify related factors and independent predictors of PPS. METHODS: All 1288 adult patients who underwent a LVHR with an expanded polytetrafluoroethylene mesh (ePTFE) between January 2003 and July 2014 were reviewed. Those who underwent an abdominal computed tomography (CT) scan more than 3 months afterwards (n = 166) were included and their scans were analysed...
January 15, 2018: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/29333590/advantages-and-disadvantages-in-image-processing-with-free-software-in-radiology
#12
Katrin Muradas Mujika, Juan Antonio Juanes Méndez, Andrés Framiñan de Miguel
Currently, there are sophisticated applications that make it possible to visualize medical images and even to manipulate them. These software applications are of great interest, both from a teaching and a radiological perspective. In addition, some of these applications are known as Free Open Source Software because they are free and the source code is freely available, and therefore it can be easily obtained even on personal computers. Two examples of free open source software are Osirix Lite® and 3D Slicer®...
January 15, 2018: Journal of Medical Systems
https://www.readbyqxmd.com/read/29333480/gpu-based-branchless-distance-driven-projection-and-backprojection
#13
Rui Liu, Lin Fu, Bruno De Man, Hengyong Yu
Projection and backprojection operations are essential in a variety of image reconstruction and physical correction algorithms in CT. The distance-driven (DD) projection and backprojection are widely used for their highly sequential memory access pattern and low arithmetic cost. However, a typical DD implementation has an inner loop that adjusts the calculation depending on the relative position between voxel and detector cell boundaries. The irregularity of the branch behavior makes it inefficient to be implemented on massively parallel computing devices such as graphics processing units (GPUs)...
December 2017: IEEE Transactions on Computational Imaging
https://www.readbyqxmd.com/read/29329601/nicotiana-glauca-whole-genome-investigation-for-ct-dna-study
#14
Galina Khafizova, Pavel Dobrynin, Dmitrii Polev, Tatiana Matveeva
OBJECTIVE: Nicotiana glauca (tree tobacco) is a naturally transgenic plant, containing sequences acquired from Agrobacterium rhizogenes by horizontal gene transfer. Besides, N. glauca contains a wide profile of alkaloids of medical interest. DATA DESCRIPTION: We report a high-depth sequencing and de novo assembly of N. glauca full genome and analysis of genome elements with bacterial origin. The draft genome assembly is 3.2 Gb, with N50 size of 31.1 kbp. Comparative analysis confirmed the presence of single, previously described gT insertion...
January 12, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29329443/bone-formation-in-ankylosing-spondylitis-during-anti-tumour-necrosis-factor-therapy-imaged-by-18f-fluoride-positron-emission-tomography
#15
Stefan T G Bruijnen, Nicki J F Verweij, Leonie M van Duivenvoorden, Nathalie Bravenboer, Dominique L P Baeten, Christiaan J van Denderen, Irene E van der Horst-Bruinsma, Alexandre E Voskuyl, Martijn Custers, Peter M van de Ven, Joost C J Bot, Bouke J H Boden, Adriaan A Lammertsma, Otto S H Hoekstra, Pieter G H M Raijmakers, Conny J van der Laken
Objectives: Excessive bone formation is an important hallmark of AS. Recently it has been demonstrated that axial bony lesions in AS patients can be visualized using 18F-fluoride PET-CT. The aim of this study was to assess whether 18F-fluoride uptake in clinically active AS patients is related to focal bone formation in spine biopsies and is sensitive to change during anti-TNF treatment. Methods: Twelve anti-TNF-naïve AS patients [female 7/12; age 39 years (SD 11); BASDAI 5...
January 9, 2018: Rheumatology
https://www.readbyqxmd.com/read/29328792/identification-and-management-of-nontraumatic-splenic-rupture
#16
Samanthi De Silva
A 43-year old previously fit and well gentleman presented to the emergency department (ED) with a two day history of worsening epigastric pain. He had had coryzal symptoms the preceding week but had no other past medical history. He was haemodynamically stable at presentation and an ultrasound scan (US) performed in the ED could not definitively rule out intra-abdominal fluid. In view of his tender abdomen on examination and a haemoglobin level of 9.2g/dL, a computerised tomography (CT) scan was performed and revealed extensive high-density fluid within the peritoneal cavity, raising the possibility of a concealed bleed but no obvious source was identified by the scan...
December 2017: Journal of Perioperative Practice
https://www.readbyqxmd.com/read/29326030/patient-reported-outcomes-following-abiraterone-acetate-plus-prednisone-added-to-androgen-deprivation-therapy-in-patients-with-newly-diagnosed-metastatic-castration-naive-prostate-cancer-latitude-an-international-randomised-phase-3-trial
#17
Kim N Chi, Andrew Protheroe, Alfredo Rodríguez-Antolín, Gaetano Facchini, Henrik Suttman, Nobuaki Matsubara, Zhangqun Ye, Bhumsuk Keam, Ronaldo Damião, Tracy Li, Kelly McQuarrie, Bin Jia, Peter De Porre, Jason Martin, Mary B Todd, Karim Fizazi
BACKGROUND: In the LATITUDE trial, addition of abiraterone acetate plus prednisone to androgen deprivation therapy (ADT) improved overall survival compared with placebos plus ADT in patients with newly diagnosed, high-risk, metastatic castration-naive prostate cancer. Understanding the effects of treatments on patient-reported outcomes (PROs) and health-related quality of life (HRQOL) is important for treatment decisions; therefore we aimed to analyse the effects of ADT plus abiraterone acetate and prednisone versus ADT plus placebos on PROs and HRQOL in patients in the LATITUDE study...
January 8, 2018: Lancet Oncology
https://www.readbyqxmd.com/read/29325432/risk-factors-for-primary-failure-of-metallic-ureteral-stents-experience-from-a-tertiary-center
#18
Jui-Shan Hsu, Chao-Yuan Huang, Kao-Lang Liu, Po-Ming Chow
INTRODUCTION: We provide primary patency rate of metallic ureteral stents in cancer patients and investigate the factors affecting primary patency. METHODS: All cancer patients who had received metallic stents for malignant ureteral obstruction between July 2009 and November 2012 in our institute were included. No patients were excluded. Patient profiles, imaging studies, and lab data were collected. Patient profiles included age, gender, body height, body weight, body mass index, cancer types, treatment for cancer, response to cancer treatment, methods of stent insertion, and prior ordinary stents...
January 12, 2018: Journal of Endourology
https://www.readbyqxmd.com/read/29323195/gastropod-shell-size-and-architecture-influence-the-applicability-of-methods-used-to-estimate-internal-volume
#19
Marilia Nagata Ragagnin, Daniel Gorman, Ian Donald McCarthy, Bruno Sampaio Sant'Anna, Cláudio Campi de Castro, Alexander Turra
Obtaining accurate and reproducible estimates of internal shell volume is a vital requirement for studies into the ecology of a range of shell-occupying organisms, including hermit crabs. Shell internal volume is usually estimated by filling the shell cavity with water or sand, however, there has been no systematic assessment of the reliability of these methods and moreover no comparison with modern alternatives, e.g., computed tomography (CT). This study undertakes the first assessment of the measurement reproducibility of three contrasting approaches across a spectrum of shell architectures and sizes...
January 11, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29322653/viruses-associated-with-congenital-tremor-and-high-lethality-in-piglets
#20
F Possatti, S A Headley, R A Leme, A M Dall Agnol, E Zotti, T E S de Oliveira, A F Alfieri, A A Alfieri
The recently described atypical porcine pestivirus (APPV) has been associated with congenital tremor (CT) type A-II in piglets in different countries. Another important neurological pathogen of pigs is porcine teschovirus (PTV), which has been associated with non-suppurative encephalomyelitis in pigs with severe or mild neurological disorders. There have been no reports of APPV and/or PTV coinfection associated with CT or encephalomyelitis in Brazilian pig herds. The aim of this study was to describe the pathological and molecular findings associated with simultaneous infection of APPV and PTV in piglets with clinical manifestations of CT that were derived from a herd with high rates of CT-associated lethality...
January 10, 2018: Transboundary and Emerging Diseases
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