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https://www.readbyqxmd.com/read/29238655/duodenal-jejunal-bypass-surgery-reverses-diabetic-phenotype-and-reduces-obesity-in-db-db-mice
#1
Yongjun Liang, Yueqian Wang, Zhengdong Qiao, Ting Cao, Ying Feng, Lin Zhang, Peng Zhang
Type 2 diabetes mellitus (T2DM), a complex metabolic disorder typically accompanying weight gain, is associated with progressive β-cell failure and insulin resistance. Bariatric surgery ameliorates glucose tolerance and provides a near-perfect treatment. Duodenal-jejunal bypass (DJB) is an experimental procedure and has been studied in several rat models, but its influence in db/db mice, a transgenic model of T2DM, remains unclear. To investigate the effectiveness of DJB in db/db mice, we performed the surgery and evaluated metabolism improvement...
2017: Current Chemical Genomics and Translational Medicine
https://www.readbyqxmd.com/read/29238644/impact-of-preoperative-anemia-on-outcomes-in-adults-undergoing-elective-posterior-cervical-fusion
#2
Kevin Phan, Alexander E Dunn, Jun S Kim, John Di Capua, Sulaiman Somani, Parth Kothari, Nathan J Lee, Joshua Xu, James E Dowdell, Samuel K Cho
Study Design: Retrospective analysis of prospectively collected data. Objectives: Few studies have investigated the role of preoperative anemia on postoperative outcomes of posterior cervical fusion. This study looked to investigate the potential relationship between preoperative anemia and postoperative outcomes following posterior cervical spine fusion. Methods: Data from patients undergoing elective posterior cervical fusions between 2005 and 2012 was collected from the American College of Surgeons National Surgical Quality Improvement Program database using inclusion/exclusion criteria...
December 2017: Global Spine Journal
https://www.readbyqxmd.com/read/29229338/delayed-occurrence-of-diabetes-insipidus-following-transsphenoidal-surgery-with-radiological-evaluation-of-the-pituitary-stalk-on-magnetic-resonance-imaging
#3
Yasuhiko Hayashi, Yasuhiro Aida, Yasuo Sasagawa, Masahiro Oishi, Daisuke Kita, Osamu Tachibana, Fumiaki Ueda, Mitsutoshi Nakada
INTRODUCTION: Diabetes insipidus (DI) is a major complication of transsphenoidal surgery (TSS). DI usually occurs within a couple of days after TSS. Delayed occurrence of postoperative DI is rarely observed and its developing mechanisms remain unknown. Methods Six patients were identified as having postoperative delayed DI, which was defined as DI that first occurred two or more weeks after TSS. They consisted of one male and five females, and their mean age was 38.3 (range: 10-76) years...
December 8, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29227187/laparoscopic-sleeve-gastrectomy-endoscopic-findings-and-gastroesophageal-reflux-symptoms-at-18-month-follow-up
#4
Germán Viscido, Verónica Gorodner, Franco Signorini, Luciano Navarro, Lucio Obeide, Federico Moser
INTRODUCTION: Laparoscopic sleeve gastrectomy (LSG) has shown excellent results in terms of weight loss and resolution of comorbidities. Despite that, the effect of LSG on gastroesophageal reflux disease (GERD) is still a controversial topic. Our objective was to evaluate the presence of gastroesophageal reflux symptoms, erosive esophagitis (EE), and hiatal hernia (HH) in obese patients undergoing LSG. METHODS: Prospective observational study. LSG patients were studied before and at 18-month follow-up...
December 11, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29227039/mid-term-results-of-bariatric-surgery-in-morbidly-obese-japanese-patients-with-slow-progressive-autoimmune-diabetes
#5
Kohei Uno, Yosuke Seki, Kazunori Kasama, Kotaro Wakamatsu, Kenkichi Hashimoto, Akiko Umezawa, Katsuhiko Yanaga, Yoshimochi Kurokawa
INTRODUCTION: Bariatric surgery is recognized as an effective treatment for type 2 diabetes mellitus, but data on its efficacy for type 1 diabetes mellitus, especially slowly progressive insulin-dependent diabetes mellitus, are limited. METHODS: We investigated five Japanese patients with slowly progressive insulin-dependent diabetes mellitus who underwent bariatric surgery at our center. RESULTS: Five morbidly obese glutamic acid decarboxylase antibody-positive diabetic patients underwent two different types of bariatric surgery...
December 11, 2017: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/29225058/impact-of-comorbidities-on-functional-recovery-from-partial-nephrectomy
#6
Sudhir Isharwal, Wenda Ye, Alice Wang, Joseph Abraham, Joseph Zabell, Wen Dong, Jitao Wu, Chalairat Suk-Ouichai, Elvis R Caraballo, Tianming Gao, Steven C Campbell
PURPOSE: Preservation of parenchymal mass and ischemia type/duration can influence functional recovery after partial nephrectomy (PN). Some have hypothesized that relevant comorbidities may also impact nephron stability and functional recovery, but this has not been adequately investigated. MATERIALS/METHODS: 405 patients with PN at our center (2007-2015) had necessary data to determine function and parenchymal mass preserved within the ipsilateral kidney. Comorbidities potentially associated with renal functional status were reviewed, including various degrees of hypertension, diabetes, cardiovascular disease, obesity, smoking status, and use of related medications...
December 7, 2017: Journal of Urology
https://www.readbyqxmd.com/read/29224190/metabolic-surgery-for-the-treatment-of-type-2-diabetes-in-obese-individuals
#7
REVIEW
David E Cummings, Francesco Rubino
Several bariatric operations originally designed to promote weight loss have been found to powerfully treat type 2 diabetes, causing remission in most cases, through diverse mechanisms additional to the secondary consequences of weight loss. These observations have prompted consideration of such operations as 'metabolic surgery', used expressly to treat diabetes, including among patients who are only mildly obese or merely overweight. Large, long-term observational studies consistently demonstrate that bariatric/metabolic surgery is associated with reductions in all cardiovascular risk factors, actual cardiovascular events, microvascular diabetes complications, cancer and death...
December 9, 2017: Diabetologia
https://www.readbyqxmd.com/read/29223421/a-prospective-multi-institutional-cohort-study-of-mediastinal-infections-after-cardiac-operations
#8
Louis P Perrault, Katherine A Kirkwood, Helena L Chang, John C Mullen, Brian C Gulack, Michael Argenziano, Annetine C Gelijns, Ravi K Ghanta, Bryan A Whitson, Deborah L Williams, Nancy M Sledz-Joyce, Brian Lima, Giampaolo Greco, Nishit Fumakia, Eric A Rose, John D Puskas, Eugene H Blackstone, Richard D Weisel, Michael E Bowdish
BACKGROUND: Mediastinal infections are a potentially devastating complication of cardiac operations. This study analyzed the frequency, risk factors, and perioperative outcomes of mediastinal infections after cardiac operations. METHODS: In 2010, 5,158 patients enrolled in a prospective study evaluating infections after cardiac operations and their effect on readmissions and mortality for up to 65 days after the procedure. Clinical and demographic characteristics, operative variables, management practices, and outcomes were compared for patients with and without mediastinal infections, defined as deep sternal wound infection, myocarditis, pericarditis, or mediastinitis...
December 6, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29222669/the-preoperative-hba1c-level-is-an-independent-prognostic-factor-for-the-postoperative-survival-after-resection-of-non-small-cell-lung-cancer-in-elderly-patients
#9
Makoto Motoishi, Satoru Sawai, Tetsuo Hori, Naoki Yamashita
PURPOSE: The aim of this study was to investigate the influence of a history of diabetes mellitus (DM) and the glycated hemoglobin (HbA1c) level on the survival in patients who underwent complete resection for non-small cell lung cancer (NSCLC). METHODS: Of the patients who underwent complete resection for NSCLC between 2007 and 2015, 468 were classified into DM (who were currently taking medication for DM) and no DM groups as well as into high HbA1c (≥ 6.5) and normal HbA1c (< 6...
December 8, 2017: Surgery Today
https://www.readbyqxmd.com/read/29221299/surgical-site-infections-after-lung-resection-a-prospective-study-of-risk-factors-in-1-091-consecutive-patients
#10
Andrea Imperatori, Elisa Nardecchia, Lorenzo Dominioni, Daniele Sambucci, Sebastiano Spampatti, Giancarlo Feliciotti, Nicola Rotolo
Background: To assess incidence and risk factors of surgical site infections (SSI) (wound infection, pneumonia, empyema) in a monocentric series of patients undergoing lung resection over a decade. Methods: All patients undergoing lung resection at our institution in 2006-2015 [wedge resection, n=579; lobectomy, n=472 (12% after chemo/radiotherapy); pneumonectomy, n=40 (47% after chemo/radiotherapy)], were prospectively enrolled. Perioperative SSI risk factors were recorded: age, gender, blood haemoglobin, lymphocyte count, serum albumin, forced expiratory volume in 1 second percentage (FEV1%) of predicted, antibiotic prophylaxis, length of stay, diabetes, malignancy, steroid therapy, induction chemo/radiotherapy, resection in 2006-2010/2011-2015, urgent/elective procedure, videothoracoscopic/open approach, resection type, operative time...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29217435/determination-of-risk-factors-and-establishment-of-a-prediction-model-for-immediate-technical-failure-during-endovascular-treatment-of-femoropopliteal-occlusive-disease
#11
Yi-Hui Qiu, Guan-Feng Yu, Huan-Hao Zhou, Hu-Wei Xia, Li Chen, Hao-Tian Chen, Yuan-Yong Jiao, Zi-Heng Wu, Xiang-Tao Zheng
PURPOSE: This study aims to reveal risk factors and establish a prediction model for the immediate technical failure (ITF) of endovascular treatment (EVT) in femoropopliteal occlusive disease (FPOD) patients based on preoperative clinical data. METHODS: A retrospective analysis of 1563 FPOD patients who underwent above-the-knee EVT was undertaken. Univariate analysis with Chi-square test was used to screen risk factors from preoperative clinical data. Multivariable analysis with logistic regression was used to generate a model for predicting the ITF rate of EVT, which was evaluated through the receiver operator characteristic curve and another independent cohort of 242 FPOD patients...
December 4, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29215497/gender-differences-for-anterior-cervical-fusion-complications-and-length-of-stay
#12
Bryce A Basques, Fady Y Hijji, Benjamin Khechen, Brittany E Haws, Benjamin C Mayo, Dustin H Massel, Philip K Louie, Kaitlyn L Cardinal, Jordan A Guntin, Kern Singh
STUDY DESIGN: Retrospective cohort OBJECTIVE.: To assess differences in baseline characteristics between genders of patients undergoing anterior cervical discectomy and fusion (ACDF) and risk factors for adverse outcomes according to gender. SUMMARY OF BACKGROUND DATA: ACDF is a common treatment for cervical spine disease. To reduce the rate of complications, risk factors associated for adverse events have been identified. However, few studies have examined the risk for inferior outcomes or complications following ACDF by gender...
December 5, 2017: Spine
https://www.readbyqxmd.com/read/29214401/predictors-of-surgical-outcomes-for-severe-cubital-tunnel-syndrome-a-review-of-146-patients
#13
Jinsong Tong, Zhen Dong, Bin Xu, Chenggang Zhang, Yudong Gu
BACKGROUND: Full recovery is unlikely for severe cubital tunnel syndrome, and prognostic factors remain uncertain. We aimed to identify predictors of surgical outcome for these patients. METHODS: One hundred forty-six patients with McGowan grade III cubital tunnel syndrome were evaluated retrospectively with a minimum follow-up of 2 years. All patients underwent either in situ decompression or subcutaneous transposition. The primary outcome measure was postoperative McGowan grade...
December 7, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29209981/the-effect-of-frailty-index-on-early-outcomes-after-combined-colorectal-and-liver-resections
#14
Sophia Y Chen, Miloslawa Stem, Marcelo Cerullo, Susan L Gearhart, Bashar Safar, Sandy H Fang, Matthew J Weiss, Jin He, Jonathan E Efron
BACKGROUND: Although previous studies have examined frailty as a potential predictor of adverse surgical outcomes, little is reported on its application. We sought to assess the impact of the 5-item modified frailty index (mFI) on morbidity in patients undergoing combined colorectal and liver resections. METHODS: Adult patients who underwent combined colorectal and liver resections were identified using the ACS-NSQIP database (2005-2015). The 5-item mFI consists of history of chronic obstructive pulmonary disease, congestive heart failure, hypertension, diabetes, and partial/total dependence...
December 5, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/29200823/six-month-postoperative-outcomes-of-intraoperative-oct-guided-surgical-cystotomy-for-refractory-cystoid-macular-edema-in-diabetic-eyes
#15
Yuichi Asahina, Naoko Tachi, Yumi Asahina, Kayoko Yoshimura, Yoshiki Ueta, Yoshihiro Hashimoto
Purpose: This study evaluated the outcomes of surgical cystotomy for recurrent diabetic cystoid macular edema (CME). Patients and methods: We analyzed 20 eyes with a clinical diagnosis of diabetic retinopathy and refractory CME. Release of vitreoretinal adhesion, epiretinal membrane (ERM) and internal limiting membrane (ILM) peeling and cystotomy guided by intraoperative optical coherence tomography (iOCT) were performed in every patient. Pars plana vitrectomy was also performed in 17 patients, 11 of whom also underwent lensectomy and intraocular lens implantation...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29199470/risk-factors-for-30-day-complications-after-thumb-cmc-joint-arthroplasty-an-american-college-of-surgeons-national-surgery-quality-improvement-program-study
#16
Kalpit N Shah, Steven F Defroda, Bo Wang, Arnold-Peter C Weiss
BACKGROUND: The first carpometacarpal (CMC) joint is a common site of osteoarthritis, with arthroplasty being a common procedure to provide pain relief and improve function with low complications. However, little is known about risk factors that may predispose a patient for postoperative complications. METHODS: All CMC joint arthroplasty from 2005 to 2015 in the prospectively collected American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database were identified...
December 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/29199401/factors-associated-with-postoperative-diabetes-insipidus-after-pituitary-surgery
#17
Antonio L Faltado, Anna Angelica Macalalad-Josue, Ralph Jason S Li, John Paul M Quisumbing, Marc Gregory Y Yu, Cecilia A Jimeno
BACKGROUND: Determining risk factors for diabetes insipidus (DI) after pituitary surgery is important in improving patient care. Our objective is to determine the factors associated with DI after pituitary surgery. METHODS: We reviewed records of patients who underwent pituitary surgery from 2011 to 2015 at Philippine General Hospital. Patients with preoperative DI were excluded. Multiple logistic regression analysis was performed and a predictive model was generated...
November 21, 2017: Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29188384/long-term-effects-of-complications-and-vascular-comorbidity-in-idiopathic-normal-pressure-hydrocephalus-a-quality-registry-study
#18
Kerstin Andrén, Carsten Wikkelsö, Nina Sundström, Simon Agerskov, Hanna Israelsson, Katarina Laurell, Per Hellström, Mats Tullberg
BACKGROUND: There is little knowledge about the factors influencing the long-term outcome after surgery for idiopathic normal pressure hydrocephalus (iNPH). OBJECTIVE: To evaluate the effects of reoperation due to complications and of vascular comorbidity (hypertension, diabetes, stroke and heart disease) on the outcome in iNPH patients, 2-6 years after shunt surgery. METHODS: We included 979 patients from the Swedish Hydrocephalus Quality Registry (SHQR), operated on for iNPH during 2004-2011...
November 29, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/29187047/defining-and-using-preoperative-predictors-of-diabetic-remission-following-bariatric-surgery
#19
Ryan Stallard, Vic Sahai, John W Drover, Shannon Chun, Christian Keresztes
BACKGROUND: Diabetes remission is defined as the return of glycemic control in the absence of medication or insulin use after bariatric surgery. We sought to identify and assess the clinical utility of a predictive model for remission of type 2 diabetes mellitus in a population seeking bariatric surgery. METHOD: A retrospective cohort design was applied to presurgical data on patients referred for Roux-en-Y gastric bypass (RYGB) or vertical sleeve gastrectomy (VSG)...
March 1, 2017: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29186533/surgical-treatment-for-isolated-mitral-valve-endocarditis-a-16-year-single-centre-experience
#20
Sossio Perrotta, Victoria Fröjd, Vincenzo Lepore, Henrik Schersten, Anders Jeppsson, Gunnar Svensson
OBJECTIVES: Despite progress in management, mitral valve endocarditis (MVE) is still a life-threatening disease. We report our experience in surgical treatment of infective isolated MVE. METHODS: A total of 140 operations in 128 patients for MVE performed between January 2000 and December 2015 were included in a retrospective study. There were 109 (78%) operations for native and 31 (22%) operations for prosthetic valve endocarditis. Preoperative and postoperative characteristics and mortality of patients were registered...
November 27, 2017: European Journal of Cardio-thoracic Surgery
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