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https://www.readbyqxmd.com/read/29160637/fetal-surgery-for-lower-urinary-tract-obstruction-the-importance-of-staging-prior-to-intervention
#1
Elizabeth A Enninga, Rodrigo Ruano
Fetal lower urinary tract obstruction (LUTO) is a heterogeneous pathology associated with a high morbidity and mortality due to pulmonary hypoplasia. Previously, when a fetus was diagnosed on ultrasound with LUTO, expectant care or termination was the only option; this has changed because of fetal surgical intervention. Vesicoamniotic shunts and cystoscopy are the current methods utilized to treat LUTO; however, it remains difficult to determine whether or not fetal prognosis favors intervention and long term outcome follow up has been limited...
November 21, 2017: Minerva Pediatrica
https://www.readbyqxmd.com/read/29148427/urothelial-carcinoma-of-the-bladder-in-pediatric-patient-four-case-series-and-review-of-the-literature
#2
Murat Uçar, Metin Demirkaya, Berna Aytaç Vuruşkan, Emin Balkan, Nizamettin Kılıç
BACKGROUND: Urothelial carcinoma (UC) of bladder is a rare condition in children. Majority of the cases are non-invasive and low grade in this age group. However, there is no follow-up protocol defined for this patient group. The objective of this study is to draw attention to childhood bladder tumors and focus on current recommendations for postoperative follow-up together with our experience with four cases. CASE REPORT: A total of 4 cases aged under the age of 18, who were treated in our clinics between 2001 and 2015 with the diagnosis of urothelial carcinoma were retrospectively evaluated...
November 17, 2017: Balkan Medical Journal
https://www.readbyqxmd.com/read/29148015/clinical-performance-and-utility-of-a-nnmt-based-urine-test-for-bladder-cancer
#3
Valentina Pozzi, Giulia Di Ruscio, Davide Sartini, Roberto Campagna, Riccardo Seta, Paola Fulvi, Alexia Vici, Giulio Milanese, Gabriele Brandoni, Andrea B Galosi, Rodolfo Montironi, Monia Cecati, Monica Emanuelli
BACKGROUND: Bladder cancer (BC) represents the most common neoplasm of the urinary tract. Although cystoscopy and urine cytology represent the gold standard methods to monitor BC, both procedures have limitations. Therefore, the identification of reliable biomarkers for early and noninvasive detection of BC is urgently required. METHODS: In this study, we analyzed nicotinamide N-methyltransferase (NNMT) expression in urine samples from 55 BC patients and 107 controls, using real-time polymerase chain reaction (PCR)...
November 11, 2017: International Journal of Biological Markers
https://www.readbyqxmd.com/read/29146217/bladder-herpes-infection-in-a-patient-with-low-grade-non-muscle-invasive-bladder-cancer
#4
Pablo Garrido-Abad, Ariel Díaz-Menéndez, Manuel Fernández-Arjona
Bladder herpes is a very uncommon event related to herpes simplex virus infection. We report a 69-year-old man with 4-year history of bladder cancer who presented with presented with dysuria and urinary frequency. Cystoscopy showed erythematous lesion of the bladder mucosa that was biopsied and revealed multi-lobed nuclei with eosinophilic intranuclear inclusions, and presence of intracytoplasmic vacuoles that were suggestive of bladder involvement by herpes simplex virus (HSV). Different bladder disorders have been associated to herpes virus, but spontaneous resolution generally occurs in 1 to 2 months...
November 13, 2017: Urology
https://www.readbyqxmd.com/read/29141603/detect-i-detect-ii-a-study-protocol-for-a-prospective-multicentre-observational-study-to-validate-the-uromark-assay-for-the-detection-of-bladder-cancer-from-urinary-cells
#5
Wei Shen Tan, Andrew Feber, Liqin Dong, Rachael Sarpong, Sheida Rezaee, Simon Rodney, Pramit Khetrapal, Patricia de Winter, Frelyn Ocampo, Rumana Jalil, Norman R Williams, Chris Brew-Graves, John D Kelly
BACKGROUND: Haematuria is a common finding in general practice which requires visual inspection of the bladder by cystoscopy as well as upper tract imaging. In addition, patients with non-muscle invasive bladder cancer (NMIBC) often require surveillance cystoscopy as often as three monthly depending on disease risk. However, cystoscopy is an invasive procedure which is uncomfortable, requires hospital attendance and is associated with a risk of urinary tract infection. We have developed the UroMark assay, which can detect 150 methylation specific alteration specific to bladder cancer using DNA from urinary sediment cells...
November 15, 2017: BMC Cancer
https://www.readbyqxmd.com/read/29135143/-the-effectiveness-of-uroprofit-in-women-with-chronic-cystitis
#6
A I Neimark, B A Neimark, N A Nozdrachev, K A Sizov, M V Razdorskaya
AIM: To evaluate the effectiveness of the biologically active dietary supplement Uroprofit in the comprehensive management of exacerbations of chronic recurrent cystitis in women. MATERIALS AND METHODS: We examined 40 women with chronic cystitis aged 20-68 years. All patients were allocated to receive either monotherapy with fosfomycin (Monural) (control group, n=20) or combination therapy with fosfomycin and biologically active dietary supplement Uroprofit (study group, n=20)...
October 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/29122620/three-year-outcomes-of-the-prospective-randomized-controlled-rez%C3%A5-m-system-study-convective-radiofrequency-thermal-therapy-for-treatment-of-lower-urinary-tract-symptoms-due-to-benign-prostatic-hyperplasia
#7
Kevin T McVary, Claus G Roehrborn
OBJECTIVE: To report 3-year outcomes of a prospective, multi-center, randomized, blinded control trial after treatment with convective radiofrequency (RF) water vapor thermal therapy for moderate to severe lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH). MATERIALS AND METHODS: Fifteen centers enrolled and randomized 197 men ≥50 years old with International Prostate Symptom Score (IPSS) ≥13, maximum flow rate (Qmax) ≤15 ml/s and prostate volume 30 to 80 cc to thermal therapy with Rezūm® System or control (2:1)...
November 6, 2017: Urology
https://www.readbyqxmd.com/read/29118704/spontaneous-remission-of-severe-systemic-langerhans-cell-histiocytosis-with-bladder-involvement-a-case-study
#8
Isotta M Magaton, Alexandar Tzankov, Fatime Krasniqi, Christof Rottenburger, Rosanna Zanetti-Daellenbach, Peter Grendelmeier, Viola Heinzelmann-Schwarz, Michael Mayr, Fabienne D Schwab
Background: The clinical presentation of Langerhans cell histiocytosis (LCH) is heterogeneous ranging from single-organ involvement to systemic disease causing substantial morbidity and mortality. We describe an unusual course of severe multisystem LCH with spontaneous remission. Case Presentation: We report on a 45-year-old Caucasian woman with cervical cancer, FIGO stage IVB. Five months after the end of combined radiochemotherapy and brachytherapy, the patient was readmitted because of severe dysuria...
September 2017: Case Reports in Oncology
https://www.readbyqxmd.com/read/29115014/impact-of-variant-microscopic-interpretation-of-the-ucyt-immunocytological-urine-test-for-the-detection-of-bladder-cancer
#9
Susanne Deininger, Tilman Todenhöfer, Jörg Hennenlotter, Valentina Gerber, Jennifer Schwarz, Jens Bedke, Christian Schwentner, Arnulf Stenzl, Steffen Rausch
BACKGROUND: Urinary marker tests for bladder cancer (BC) detection and surveillance represent a desirable approach to diagnosis and follow-up. The SCIMEDX uCyt+ assay detects antigens expressed by BC cells (mucin glycoprotein and carcinoembryonic antigen) using green and red fluorescence and is interpreted according to specific manufacturer's recommendations. In the present study, we evaluated divergent approaches of numeric and morphological analysis of uCyt+ to generate a rationale for alternative test interpretation strategies...
November 8, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29110046/-supplementary-optical-techniques-for-the-detection-of-nonmuscle-invasive-bladder-cancer
#10
REVIEW
S Aeishen, Y Dawood, S Papadoukakis, M Horstmann
White light cystoscopy (WL) is the gold standard for the detection of bladder cancer. It can be performed using a rigid or flexible urethrocystoscope. With the more recent introduction of high definition (HD) techniques, WL cystoscopy has been decisively improved. Supplementary optical techniques are also used to improve the detection of bladder cancer. Among these are photodynamic diagnosis (PDD), narrow-band imaging (NBI), S‑technologies of IMAGE1 S, optical coherence tomography (OCT), confocal laser endomicroscopy (CLE), and Raman spectroscopy...
November 6, 2017: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/29108916/an-evidence-based-protocol-for-antibiotic-use-prior-to-cystoscopy-decreases-antibiotic-usage-without-impacting-post-procedural-symptomatic-urinary-tract-infection-rates
#11
Justin R Gregg, Rohan G Bhalla, J Paul Cook, Caroline Lai, Roger Dmochowski, Thomas R Talbot, Daniel A Barocas
PURPOSE: Symptomatic urinary tract infection (UTI) is a complication of office-based cystourethroscopy. Studies are mixed regarding the efficacy of antibiotic prophylaxis for UTI prevention. Our aim was to develop and evaluate an evidence-based protocol that reduces unnecessary antibiotic use while avoiding an increase in UTI. MATERIALS AND METHODS: A clinic antibiogram was created based on all urology office visits performed during a two-year time period. Bacterial resistance rates, institutional risk-related data, and clinical guidelines were used to create a protocol for pre-cystourethroscopy antibiotic use...
November 3, 2017: Journal of Urology
https://www.readbyqxmd.com/read/29107431/office-stent-placement-under-local-anesthesia-is-a-safe-and-efficient-procedure-for-the-management-of-multiple-ureteral-disorders
#12
A Carrion, M D'Anna, M Costa-Grau, P Luque, E García-Cruz, A Franco, A Alcaraz
OBJECTIVE: To assess the outcomes of ureteral stent placement under local anesthesia for the management of multiple ureteral disorders. METHODS: Retrospective study of 45 consecutive ureteral stents placed under local anesthesia from January 2015 to July 2016. Inclusion criteria were hemodynamically stable patients with urinary obstruction, urinary fistula or for prophylactic ureteral localization during surgery. Five minutes before the procedure, 10ml of lidocaine gel and 50ml of lidocaine solution were instilled in the bladder...
October 26, 2017: Actas Urologicas Españolas
https://www.readbyqxmd.com/read/29103256/-a-case-of-intravesical-foreign-body-by-erosion-of-surgical-mesh-used-for-an-inguinal-hernia-repair
#13
Kota Iida, Fumiaki Hoshiyama, Masahiro Tanaka, Kiyohide Fujimoto
We report our experience with a case in which eroded mesh used for inguinal hernia repair migrated into the bladder. An 84-year-old man underwent surgery for colorectal cancer at the age of 40, and radical surgery for a right inguinal hernia at the age of 83. At his initial visit, he reported macroscopic hematuria. Cystoscopy revealed a yellowish-brown foreign body on the right bladder wall, and computed tomography showed the presence of emphysema in association with the foreign body. Based on a presumptive diagnosis of vesical calculi, transurethral lithotripsy was performed...
October 2017: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/29103255/-two-cases-of-urachal-carcinoma-treated-by-ts-1-cddp-as-adjuvant-chemotherapy
#14
Michinobu Ozawa, Akito Kuromoto, Kento Morozumi, Masahiko Satou, Senji Hoshi, Kenji Numahata
Case 1 : A 48-year-old man presenting with gross hematuria was suspected to have a tumor located in the bladder dome. He was referred to our department for further examination and treatment. Cystoscopy showed a dome-shaped mass in the supravesical region. Computed tomography and magnetic resonance imaging indicated the possibility of urachal carcinoma and peritoneal dissemination. Therefore, partial cystectomy with urachal resection was performed. The intraoperative findings were disseminated peritoneal nodules and mucus entering the peritoneal cavity from the tumor...
October 2017: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/29102559/direct-observation-vs-video-based-assessment-in-flexible-cystoscopy
#15
Julia Dagnaes-Hansen, Oria Mahmood, Sarah Bube, Flemming Bjerrum, Yousif Subhi, Malene Rohrsted, Lars Konge
OBJECTIVE: Direct observation in assessment of clinical skills is prone to bias, demands the observer to be present at a certain location at a specific time, and is time-consuming. Video-based assessment could remove the risk of bias, increase flexibility, and reduce the time spent on assessment. This study investigated if video-based assessment was a reliable tool for cystoscopy and if direct observers were prone to bias compared with video-raters. DESIGN: This study was a blinded observational trial...
October 25, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/29100651/management-of-iatrogenic-cystoscopic-urethral-lesion-associated-with-sequela-of-cuff-erosion-in-a-patient-after-previous-ams-800-implantation-one-step-technique-with-revision-without-cuff-explantation
#16
P Weibl, M Rutkowski, W Huebner
INTRODUCTION: Iatrogenic urethral lesion with subsequent cuff erosion during cystoscopy is a rare complication. The alternative surgical strategy with in situ urethroplasty while maintaining the open cuff left in situ will be presented. MATERIALS AND METHODS: The authors report 3cases of iatrogenic urethral lesion with cuff erosion during cystoscopic evaluation to exclude stricture or cuff erosion due to new onset of obstructive lower urinary tract symptoms. All patients had a history of a AMS 800 implantation due to posprostatectomy incontinence...
October 31, 2017: Actas Urologicas Españolas
https://www.readbyqxmd.com/read/29099383/does-using-alprazolam-during-outpatient-flexible-cystoscopy-decrease-anxiety-and-pain
#17
Tayyar Alp Ozkan, Sefik Koprulu, Ayhan Karakose, Ozdal Dillioglugil, Ibrahim Cevik
OBJECTIVES: To evaluate the effect of pre-operative alprazolam medication on anxiety and pain in flexible cystoscopy for bladder cancer follow-up. METHODS: A total of 86 male patients who had flexible cystoscopy for bladder cancer follow-up at 6th and 9th months were included in the study. A visual analog scale (VAS) pain score and the State-Trait Anxiety Inventory (STAI) were used. The 6th (VAS-1)and 9th (VAS-2) month pain scores and 6th month STAI score (STAI-1) and, 9th month STAI score before (STAI-2a) and after alprazolam (0...
November 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/29094888/bladder-cancer-diagnosis-and-treatment
#18
Katharine C DeGeorge, Harry R Holt, Stephanie C Hodges
Bladder cancer is the sixth most prevalent malignancy in the United States and causes more than 16,000 deaths annually. The most common clinical presentation is asymptomatic hematuria, which should prompt evaluation with cystoscopy, renal function testing, and upper urinary tract imaging in adults 35 years and older and in those with irritative voiding symptoms, risk factors for bladder cancer, or gross hematuria at any age. Transurethral resection of the bladder tumor allows for definitive diagnosis, staging, and primary treatment...
October 15, 2017: American Family Physician
https://www.readbyqxmd.com/read/29089678/an-extremely-rare-case-of-dermoid-cyst-of-urinary-bladder
#19
Chirag Jain, Mahesh K Mittal, Fouzia Shiraz
We report an extremely rare case of a dermoid cyst of the urinary bladder in a 30-year-old female who presented with pain in the left flank and dysuria since 9 months. On imaging (ultrasound and computed tomography), a relatively well-defined mass lesion with areas of fat and calcification was seen arising from the bladder wall. Cystoscopy showed presence of hair on the surface of the lesion. Histopathological findings were consistent with dermoid cyst in the urinary bladder.
July 2017: Indian Journal of Radiology & Imaging
https://www.readbyqxmd.com/read/29082325/endoscopic-treatment-of-intrauterine-device-migration-into-the-bladder-with-stone-formation
#20
Masayuki Sano, Kaoru Nemoto, Takafumi Miura, Yasutomo Suzuki
Background: An intrauterine device is commonly used for contraception globally. Although intrauterine device placement is an effective and safe method of contraception, migration into the bladder with stone formation is a rare and serious complication. The management approaches for an intrauterine device embedded in the bladder include endoscopic procedures and open surgical removal. In this study, we report the case of a patient with recurrent urinary tract infection associated with intrauterine device migration and urolithiasis, who successfully underwent endoscopic treatment combined with laser fragmentation...
2017: Journal of Endourology Case Reports
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