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https://www.readbyqxmd.com/read/27913867/comparison-of-different-concepts-for-interpretation-of-chromosomal-aberrations-in-urothelial-cells-detected-by-fluorescence-in-situ-hybridization
#1
Johannes Mischinger, Lutz Philipp Guttenberg, Jörg Hennenlotter, Georgios Gakis, Stefan Aufderklamm, Steffen Rausch, Eva Neumann, Jens Bedke, Stefan Kruck, Christian Schwentner, Arnulf Stenzl, Tilman Todenhöfer
PURPOSE: Urine fluorescence in situ hybridization (FISH) has become a broadly used marker for noninvasive detection of bladder cancer (BC). However, it has been discussed whether the interpretation algorithm proposed by the manufacturer could be improved. Aim of the present study was to compare alternative evaluation strategies of FISH for detection of BC. METHODS: We included 1048 patients suspicious for BC, who underwent urine FISH examination before cystoscopy (diagnostic cohort)...
December 2, 2016: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/27895447/intrauterine-device-migration-to-the-urinary-bladder-causing-sexual-dysfunction-a-case-report
#2
K Dimitropoulos, K Skriapas, G Karvounis, V Tzortzis
BACKGROUND: Intravesical migration represents an uncommon complication of intrauterine device (IUD) insertion. We present the case of an IUD that migrated to the urinary bladder, causing significant sexual complaints. CASE REPORT: A 38-year-old woman presented with complaints of gradually evolving dyspareunia and recurrent urinary tract infections during the past 12 months. She reported an IUD insertion 18 months before. Further detailed evaluation revealed disorders in all sexual domains...
January 2016: Hippokratia
https://www.readbyqxmd.com/read/27895377/frequency-and-predictors-of-recurrence-of-bladder-tumour-on-first-check-cystoscopy-a-tertiary-care-hospital-experience
#3
Muhammad Farhan, Syed Muhammad Nazim, Jibran Ahmed, Muhammad Hammad Ather
OBJECTIVE: To determine the frequency and predictors of non-muscle invasive bladder tumour recurrence on first-check cystoscopy after transurethral resection of bladder tumour. METHODS: This cross-sectional study was conducted at the Aga Khan University Hospital, Karachi, from April to November 2014, and comprised patients with a suspected newly-diagnosed urothelial cancer. Patients with non-muscle invasive disease with complete resection of all visible lesions along with deep biopsy from the tumour base were included...
October 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/27894979/-comparison-of-white-light-photodynamic-diagnosis-and-narrow-band-imaging-in-detection-of-carcinoma-in-situ-cis-or-flat-dysplasia-at-transurethral-resection-of-the-bladder-the-dablaca-8-study
#4
Ditte Drejer, Sami Béji, Recep Oezeke, Anna Munk Nielsen, Søren Høyer, Truls Erik Bjerklund Johansen, Gitte W Lam, Jørgen B Jensen
: Photodynamic diagnosis (PDD) and narrow band imaging (NBI) are two different modalities used to improve detection of tumors, carcinoma in situ (CIS) and flat dysplasia compared to white light (WL) cystoscopy. OBJECTIVES: To compare findings in NBI to findings in WL and PDD in a high risk patient population. DESIGN, SETTING, AND PARTICIPANTS: 171 patients were included in the study from four different urological departments in Denmark and Norway...
November 25, 2016: Urology
https://www.readbyqxmd.com/read/27888870/latest-advances-in-pancreatic-tumours
#5
José Lariño Noia
Pancreatic cancer continues to have a bleak prognosis. Hardly any therapeutic advances have been made in the last few years and consequently most efforts have focused on preventing its development and on diagnosing precursor lesions. In this regard, the use of statins as a preventive factor and the implementation of screening programmes in high-risk patients are gaining ground. In the field of treatment, there is greater focus on the role of neoadjuvant therapy in pancreatic cancer and on a multimodal approach to the disease, with few advances in effective novel therapies...
September 2016: Gastroenterología y Hepatología
https://www.readbyqxmd.com/read/27888433/clinical-significance-of-incidentally-detected-bladder-wall-thickening-on-computed-tomography
#6
Wan Song, Hwang Gyun Jeon, Byong Chang Jeong, Seong Il Seo, Seong Soo Jeon, Han Yong Choi, Hyun Moo Lee
PURPOSE: To evaluate the clinical significance of incidentally detected bladder wall thickening (BWT) on computed tomography (CT). METHODS: A retrospective analysis was performed on 34,793 cystoscopy cases between January 2004 and December 2013. Among these, patients who underwent cystoscopy for the sole indication of incidentally detected BWT on CT were selected. Patients were categorized into the diffuse or focal group depending on the extent of BWT. Suspicious lesions on cystoscopy were biopsied to confirm histologic subtype...
November 25, 2016: International Urology and Nephrology
https://www.readbyqxmd.com/read/27887713/magnetic-resonance-imaging-correlation-to-intraoperative-findings%C3%A2-of-deeply-infiltrative-endometriosis
#7
Traci E Ito, Elias D Abi Khalil, Myles Taffel, Gaby N Moawad
OBJECTIVE: To show characteristics of deeply infiltrative endometriosis (DIE) on magnetic resonance imaging (MRI) and how they correlate with intraoperative findings. DESIGN: Overview of still and dynamic MRI images of four different patients with DIE. We then used videos from their surgeries to highlight the appearance of endometriosis corresponding to these images (educational video). SETTING: University hospital. PATIENT(S): Four different patients with DIE were included in this video...
November 22, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27866214/vesicouterine-fistula-teaching-video-on-diagnosis-and-surgical-treatment
#8
Pilar Marin-Sanchez, Maria Luisa Sánchez-Ferrer, Clara Garrido-Navarro, Antonio Prieto-Gonzalez, Francisco Machado-Linde
INTRODUCTION: A 42-year-old woman presented with urinary incontinence 9 years after the last of four vaginal deliveries. She had also had one Caesarean section. Immediately after the last delivery, she presented with haematuria, which resolved within a few hours, but the drain remained prophylactically for 7 days. Nine years later, she was referred to a specialist hospital. METHOD: The patient presented with continuous urinary incontinence, and physical examination revealed a loss of urine from the vagina, the latter confirmed by a methylene blue test showing loss of urine from the uterine cervix...
November 19, 2016: International Urogynecology Journal
https://www.readbyqxmd.com/read/27861259/tailored-perioperative-antimicrobial-prophylaxis-in-urological-surgery-myth-or-reality
#9
Magnus J Grabe, Karl-Johan Lundström
PURPOSE OF THE REVIEW: The controversies surrounding perioperative antimicrobial prophylaxis (AMP) are about the use and especially misuse of antibiotics. The overall lack of evidence to facilitate a rational perioperative AMP policy in urological surgery and the postoperative infectious complications remain a challenge. Therefore, a basic tool to aid decision-making would be useful. A model based on the patients' risk factors, the level of contamination and grading of surgical procedures is discussed...
November 24, 2016: Current Opinion in Urology
https://www.readbyqxmd.com/read/27859848/evaluation-of-double-immunocytochemical-staining-for-ck20-and-p53-as-a-potential-adjunct-to-cytology-for-urothelial-cancer-diagnosis
#10
M Lenos, I Katafigiotis, K Vrettou, D Papaioannou, F Malta, E-A Trigka, S Sousouris, C Constantinides, P Mikou
OBJECTIVE: To evaluate double immunocytochemical staining with p53 and CK20, as a tool for improving the accuracy of urinary cytology. The aim of the present study was to clarify the diagnostic significance of the expression of these markers and to investigate the possibility of using this information for better monitoring of bladder cancer patients during follow-up. MATERIAL AND METHODS: One hundred and twenty-five urine cytology cases were retrieved with corresponding histology from our files...
November 18, 2016: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/27847920/removal-of-foreign-bodies-embedded-in-the-urinary-bladder-wall-by-a-combination-of-laparoscopy-and-carbon-dioxide-cystoscopic-assistance-case-report-and-literature-review
#11
Chengyue Jin, Yu Fan, Qian Zhang, Yu Wang, Shiliang Wu, Jie Jin
PURPOSE: To report a case of combined laparoscopic and carbon dioxide partial cystectomy and foreign body removal and to review the existing literature on the topic. MATERIALS AND METHODS: A 43-year-old Asian woman was found to have an intrauterine device embedded in the bladder wall during evaluation for chronic pelvic pain and urinary tract infection. She underwent cystoscopic-laparoscopic partial cystectomy, with an uncomplicated postoperative course. She had normal renal function during the follow-up period...
November 2016: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/27845696/prospective-non-randomized-study-on-the-use-of-antibiotic-prophylaxis-with-ciprofloxacin-in-flexible-urethrocystoscopy
#12
María Carmen Cano-García, Rosario Casares-Pérez, Miguel Arrabal-Martín, Sergio Merino-Salas, Miguel Ángel Arrabal-Polo
OBJECTIVE: The goal of this study is to analyze whether there is a need for antibiotic prophylaxis in this outpatient procedure. METHODS: Prospective observational non-randomized study including 100 patients divided into two groups: - Group 1: 48 patients receiving 500 mg of ciprofloxacin prophylaxis 1 hour before urethrocystoscopy; - Group 2: 52 patients without antibiotic prophylaxis. Before inclusion of the patients in the study, we checked the absence of urinary tract infection by means of a urinalysis obtained 3 days before the procedure...
November 2016: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/27842627/polyarteritis-nodosa-presenting-as-a-bladder-outlet-obstruction
#13
M Borkum, H Y Abdelrahman, R Roberts, A A Kalla, I G Okpechi
Polyarteritis nodosa (PAN) of the urinary tract is rare. An unusual case of systemic PAN involving the bladder neck is described. A 27-year-old man, with known diastolic hypertension diagnosed 2 years earlier, was admitted with chronic urinary obstruction complicated by hydronephrosis. He had symptoms of myalgia and weight loss, was afebrile but had an elevated erythrocyte sedimentation rate and acute-on-chronic renal impairment. All virological and serological tests including hepatitis B and anti-neutrophil cytoplasmic antibody were negative...
November 2, 2016: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/27834090/an-unusual-case-of-urinary-bladder-arteriovenous-malformation
#14
D Gnanappiragasam, S Gnanappiragasam, T E D McDermott
A 45-year-old male presented with haematuria and urinary frequency. Computed Tomography (CT) urogram revealed gross thickening of the left bladder wall. Histology showed large vessels cuffed by eosinophonilic material suggestive of urinary bladder arteriovenous malformation (AVM). No further intervention was carried out as symptoms resolve after the resection. Follow up rigid cystoscopy and CT at 3 months showed resolution of all visible pathology and no evidence of recurrence.
August 8, 2016: Irish Medical Journal
https://www.readbyqxmd.com/read/27833981/m%C3%A3-llerianosis-of-the-urinary-bladder-a-rare-case-report-and-review-of-the-literature
#15
Marius Stanimir, LuminiŢa Cristina ChiuŢu, Sébastien Wese, Amelia Milulescu, Răducu Nicolae Nemeş, Ovidiu Gabriel Bratu
The aim of this paper is to report a very rare case of müllerianosis (endosalpinx, endometrium, and endocervix) in a post-menopausal woman. Müllerianosis of the bladder is a very rare disease, which affects mainly the women of the reproductive age group, but with a good prognosis if the transitional bladder carcinoma is resolved. We present the case of a 64-year-old woman complaining of left lower abdomen pain, repeated lower and upper tract urinary infections, emergency urinary incontinence and hematuria...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/27824741/intraoperative-cystoscopic-evaluation-of-ureteral-patency-a-randomized-controlled-trial
#16
Luis Espaillat-Rijo, Lauren Siff, Alexandriah N Alas, Sami A Chadi, Stephen Zimberg, Sneha Vaish, G Willy Davila, Matthew Barber, Eric A Hurtado
OBJECTIVE: To compare different modalities to aid in the evaluation of intraoperative ureteral patency on cystoscopy in the postindigo carmine era. METHODS: In a randomized controlled trial, participants undergoing pelvic surgery were randomized into one of four groups: saline distention (control), 10% dextrose distention, oral phenazopyridine, or intravenous sodium fluorescein. Our primary outcome was visibility of the ureteral jets. Secondary outcomes included surgeon satisfaction; adverse reactions including allergies, urinary tract infections, urinary retention, cystoscopy times, and ureteral obstruction; and delayed diagnosis...
December 2016: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27824057/bladder-cancer-in-individuals-with-spinal-cord-injuries-a-meta-analysis
#17
REVIEW
L Gui-Zhong, M Li-Bo
OBJECTIVES: To conduct a scoping review of all the literature related to bladder cancer in individuals with spinal cord injuries (SCIs). METHODS: We searched for trials in MEDLINE, EMBASE, CINAHL and the Cochrane Register. Meta-analysis methods were used to evaluate these studies. RESULTS: A total of 18 articles were identified and included as the evidence base for analysis. The incidence of bladder cancer in individuals with SCI is 6‰ (95% confidence interval (CI), 5-6‰, I(2)=49...
November 8, 2016: Spinal Cord
https://www.readbyqxmd.com/read/27823975/narrow-band-imaging-assisted-transurethral-resection-reduces-the-recurrence-risk-of-non-muscle-invasive-bladder-cancer-a-systematic-review-and-meta-analysis
#18
REVIEW
Weiting Kang, Zilian Cui, Qianqian Chen, Dong Zhang, Haiyang Zhang, Xunbo Jin
CONTEXT: Compared with white light imaging (WLI) cystoscopy, narrow band imaging (NBI) cystoscopy could increase the visualization and detection of bladder cancer (BC) at the time of transurethral resection (TUR). NBI cystoscopy could increase the detection of BC, but it remains unclear whether narrow band imaging-assisted transurethral resection (NBI-TUR) could reduce the recurrence risk of non-muscle invasive bladder cancer (NMIBC). Several randomized clinical trials (RCTs) have recently tested the efficacy of NBI-TUR for NMIBC...
November 3, 2016: Oncotarget
https://www.readbyqxmd.com/read/27803508/potency-and-sterility-of-10-sodium-fluorescein-injection-usp-stored-in-sterile-polypropylene-syringes-for-use-during-cystoscopy
#19
Enrique Puertos, Greta Giles
Background: A shortage of indigotindisulfonate sodium has led to a search for an alternative visualizing agent. Objective: The primary objective of this study was to evaluate the potency and sterility of 10% sodium fluorescein, USP solutions stored in sterile polypropylene syringes and refrigerated. Methods: Four samples of 10% fluorescein injection, USP were aseptically drawn up in 3 mL polypropylene syringes and stored in a refrigerator at an average temperature of 3.9°C for 7 days. After 7 days, the samples were cultured for microbial growth...
October 2016: Hospital Pharmacy
https://www.readbyqxmd.com/read/27800658/interhospital-transfer-delays-emergency-abdominal-surgery-and-prolongs-stay
#20
Alexandra M Limmer, Michael B Edye
BACKGROUND: Interhospital transfer of patients requiring emergency surgery is common practice. It has the potential to delay surgical intervention, increase rate of complications and thus length of hospital stay. METHODS: A retrospective cohort study was conducted of adult patients who underwent emergency surgery for abdominal pain at a large metropolitan hospital in New South Wales (Hospital A) in 2013. The impact of interhospital transfer on time to surgical intervention, post-operative length of stay and overall length of stay was assessed...
November 1, 2016: ANZ Journal of Surgery
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