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https://www.readbyqxmd.com/read/27923267/sleep-and-processing-of-trauma-memories
#1
Ihori Kobayashi, Thomas A Mellman, Duaa Altaee, Mary Katherine Howell, Joseph Lavela
Sleep has been implicated in learning processes that appear to underlie recovery from posttraumatic stress disorder (PTSD). The importance of quality and timing of sleep following exposure-based therapies has been suggested. The present study evaluated relationships between sleep and adaptive emotional processing following written narrative exposure (WNE) to memories of traumatic events experienced by participants with clinically significant PTSD symptoms. Participants included 21 urban-residing nontreatment-seeking adults with full or subthreshold symptoms of PTSD who completed 4 sessions of 30-min WNE with the first session either in the evening or the morning...
December 2016: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/27923090/association-between-end-of-rotation-resident-transition-in-care-and-mortality-among-hospitalized-patients
#2
Joshua L Denson, Ashley Jensen, Harry S Saag, Binhuan Wang, Yixin Fang, Leora I Horwitz, Laura Evans, Scott E Sherman
Importance: Shift-to-shift transitions in care among house staff are associated with adverse events. However, the association between end-of-rotation transition (in which care of the patient is transferred) and adverse events is uncertain. Objective: To examine the association of end-of-rotation house staff transitions with mortality among hospitalized patients. Design, Setting, and Participants: Retrospective multicenter cohort study of patients admitted to internal medicine services (N = 230 701) at 10 university-affiliated US Veterans Health Administration hospitals (2008-2014)...
December 6, 2016: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/27923089/correlations-between-ratings-on-the-resident-annual-evaluation-summary-and-the-internal-medicine-milestones-and-association-with-abim-certification-examination-scores-among-us-internal-medicine-residents-2013-2014
#3
Karen E Hauer, Jonathan Vandergrift, Brian Hess, Rebecca S Lipner, Eric S Holmboe, Sarah Hood, William Iobst, Stanley J Hamstra, Furman S McDonald
Importance: US internal medicine residency programs are now required to rate residents using milestones. Evidence of validity of milestone ratings is needed. Objective: To compare ratings of internal medicine residents using the pre-2015 resident annual evaluation summary (RAES), a nondevelopmental rating scale, with developmental milestone ratings. Design, Setting, and Participants: Cross-sectional study of US internal medicine residency programs in the 2013-2014 academic year, including 21 284 internal medicine residents (7048 postgraduate-year 1 [PGY-1], 7233 PGY-2, and 7003 PGY-3)...
December 6, 2016: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/27923083/resident-shift-handoff-strategies-in-us-internal-medicine-residency-programs
#4
LETTER
Charlie M Wray, Saima Chaudhry, Amber Pincavage, Rachel Miller, Linda DeCherrie, Karin Ouchida, Vineet M Arora
No abstract text is available yet for this article.
December 6, 2016: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/27923078/shifting-approaches-for-evaluation-of-resident-performance-from-competencies-to-milestones
#5
EDITORIAL
Lia S Logio
No abstract text is available yet for this article.
December 6, 2016: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/27923070/macrophage-colony-stimulating-factor-derived-from-cd4-t-cells-contributes-to-control-of-a-blood-borne-infection
#6
Mary F Fontana, Gabrielly L de Melo, Chioma Anidi, Rebecca Hamburger, Chris Y Kim, So Youn Lee, Jennifer Pham, Charles C Kim
Dynamic regulation of leukocyte population size and activation state is crucial for an effective immune response. In malaria, Plasmodium parasites elicit robust host expansion of macrophages and monocytes, but the underlying mechanisms remain unclear. Here we show that myeloid expansion during P. chabaudi infection is dependent upon both CD4+ T cells and the cytokine Macrophage Colony Stimulating Factor (MCSF). Single-cell RNA-Seq analysis on antigen-experienced T cells revealed robust expression of Csf1, the gene encoding MCSF, in a sub-population of CD4+ T cells with distinct transcriptional and surface phenotypes...
December 2016: PLoS Pathogens
https://www.readbyqxmd.com/read/27923013/community-mobilization-for-hiv-testing-uptake-results-from-a-community-randomized-trial-of-a-theory-based-intervention-in-rural-south-africa
#7
Sheri A Lippman, Torsten B Neilands, Catherine MacPhail, Dean Peacock, Suzanne Maman, Dumisani Rebombo, Rhian Twine, Amanda Selin, Hannah H Leslie, Kathleen Kahn, Audrey Pettifor
BACKGROUND: HIV testing uptake in South Africa is below optimal levels. Community mobilization (CM) may increase and sustain demand for HIV testing, however, little rigorous evidence exists regarding the effect of CM interventions on HIV testing and the mechanisms of action. METHODS: We implemented a theory-driven CM intervention in 11 of 22 randomly-selected villages in rural Mpumalanga Province. Cross-sectional surveys including a community mobilization measure were conducted before (n = 1181) and after (n = 1175) a 2-year intervention (2012-2014)...
January 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27922990/robotically-assisted-thoracic-surgery-proposed-guidelines-for-privileging-and-credentialing
#8
Faiz Y Bhora, Adnan M Al-Ayoubi, Sadiq S Rehmani, Craig M Forleiter, Wissam N Raad, Scott G Belsley
OBJECTIVE: Increased use of robotically assisted thoracic surgery (RATS) necessitates effective credentialing guidelines to ensure safe outcomes. We provide a stepwise algorithm for granting privileges and credentials in RATS. This algorithm reflects graduated responsibility and complexity of the surgical procedures performed. Furthermore, it takes into account volume, outcomes, surgeon's competency, and appropriateness of robot usage. METHODS: We performed a literature review for available strategies to grant privileges and credentials for implementing robotic surgery...
December 5, 2016: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/27922718/costly-and-unnecessary
#9
Kate Harrington
Many U.S. medical students, residents, and physicians want to see the elimination of the U.S. Medical Licensing Exam Step 2 Clinical Skills exam, saying it has a high price tag and an even higher first-attempt pass rate.
December 1, 2016: Texas Medicine
https://www.readbyqxmd.com/read/27922476/perceptions-of-an-adapted-mindfulness-program-for-persons-experiencing-substance-use-disorders-and-traumatic-brain-injury
#10
Gisli K Kristofersson, Tom Beckers, Rick Krueger
BACKGROUND: Of the 1.4 million Americans who sustain traumatic brain injuries (TBIs) each year up to half experience substance use disorders (SUDs). This often leads to various issues such as increased rates of mental health problems and delay or lack of return to full employment. AIMS: The purpose of this program evaluation was to describe Vinland National Center's (Vinland's) client and staff perceptions of a 4-week mindfulness-based intervention adapted from the original mindfulness-based stress reduction program for persons experiencing SUDs and TBIs...
October 2016: Journal of Addictions Nursing
https://www.readbyqxmd.com/read/27922188/oral-health-status-of-children-in-los-angeles-county-and-in-the-united-states-1999-2004
#11
Bruce A Dye, Clemencia M Vargas, Cheryl D Fryar, Francisco Ramos-Gomez, Robert Isman
OBJECTIVE: To ascertain and compare the oral health status and related sociodemographic risk indicators in children in Los Angeles (LA) County with children in the United States. METHODS: Data from the National Health and Nutrition Examination Survey (NHANES) 1999-2004 were used to calculate prevalence estimates for children aged 2-13 years living in LA County and in the United States. Sociodemographic indicators were evaluated using multiple logistic regression modeling...
December 6, 2016: Community Dentistry and Oral Epidemiology
https://www.readbyqxmd.com/read/27922179/a-carbon-dioxide-stripping-model-for-mammalian-cell-culture-in-manufacturing-scale-bioreactors
#12
Zizhuo Xing, Amanda M Lewis, Michael C Borys, Zheng Jian Li
Control of carbon dioxide within the optimum range is important in mammalian bioprocesses at the manufacturing scale in order to ensure robust cell growth, high protein yields, and consistent quality attributes. The majority of bioprocess development work is done in laboratory bioreactors, in which carbon dioxide levels are more easily controlled. Some challenges in carbon dioxide control can present themselves when cell culture processes are scaled up, because carbon dioxide accumulation is a common feature due to longer gas-residence time of mammalian cell culture in large scale bioreactors...
December 6, 2016: Biotechnology and Bioengineering
https://www.readbyqxmd.com/read/27922142/prevalence-and-risk-factors-of-caregiver-dependence-among-older-adults-in-a-southeast-asian-population
#13
Louisa Picco, Edimansyah Abdin, Janhavi A Vaingankar, Shirlene Pang, Saleha Shafie, Rajeswari Sambasivam, Siow Ann Chong, Mythily Subramaniam
INTRODUCTION: Currently very little is known about the prevalence or magnitude of caregiver dependence in Singapore and thus, there is a need to fill this gap in this multiethnic ageing population. This study aims to determine the prevalence and risk factors of caregiver dependence among older adults in Singapore. MATERIALS AND METHODS: Data were used from the Well-being of the Singapore Elderly (WiSE) study, a nationally representative, cross-sectional survey among Singapore residents aged 60 years and above...
November 2016: Annals of the Academy of Medicine, Singapore
https://www.readbyqxmd.com/read/27922121/sex-differences-in-prevalence-of-and-risk-factors-for-carotid-plaque-among-adults-a-population-based-cross-sectional-study-in-rural-china
#14
Wei Zhao, Yanan Wu, Min Shi, Lingling Bai, Jun Tu, Zaiyu Guo, Rongcai Jiang, Jianning Zhang, Xianjia Ning, Jinghua Wang
Although the associations between carotid plaque and cardiovascular disease risk factors have been identified in previous studies, there is limited information on sex-related differences in factors associated with the development of carotid plaque. We aimed to determine sex differences in the prevalence of carotid plaque and associated risk factors in rural China. A total of 3,789 subjects aged ≥45 years without history of stroke or cardiovascular disease were recruited to the study. B-mode ultrasonography was performed to determine the presence of carotid plaque...
December 6, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27922055/limited-hiv-1-reactivation-in-resting-cd4-t-cells-from-aviremic-patients-under-protease-inhibitors
#15
Amit Kumar, Wasim Abbas, Sophie Bouchat, Jean-Stéphane Gatot, Sébastien Pasquereau, Kabamba Kabeya, Nathan Clumeck, Stéphane De Wit, Carine Van Lint, Georges Herbein
A latent viral reservoir that resides in resting CD4(+) T cells represents a major barrier for eradication of HIV infection. We test here the impact of HIV protease inhibitor (PI) based combination anti-retroviral therapy (cART) over nonnucleoside reverse transcriptase inhibitor (NNRTI)-based cART on HIV-1 reactivation and integration in resting CD4(+) T cells. This is a prospective cohort study of patients with chronic HIV-1 infection treated with conventional cART with an undetectable viremia. We performed a seven-year study of 47 patients with chronic HIV-infection treated with cART regimens and with undetectable plasma HIV-1 RNA levels for at least 1 year...
December 6, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27921300/living-in-violent-neighbourhoods-is-associated-with-gestational-weight-gain-outside-the-recommended-range
#16
Jessica Galin, Barbara Abrams, Stephanie A Leonard, Ellicott C Matthay, Dana E Goin, Jennifer Ahern
BACKGROUND: During pregnancy, most women do not meet gestational weight gain (GWG) guidelines, potentially resulting in adverse maternal and infant health consequences. Social environment determinants of GWG have been identified, but evidence on the relationship between neighbourhood violence and GWG is scant. Our study aims to examine the relationship between neighbourhood violence and GWG outside the recommended range. METHODS: We used statewide vital statistics and health care utilization data from California for 2006-12 (n = 2 364 793) to examine the relationship of neighbourhood violence (quarters of zip-code rates of homicide and assault) in the first 37 weeks of pregnancy with GWG (categorized using the Institute of Medicine's pregnancy weight gain guidelines)...
December 6, 2016: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/27921293/coloniality-and-migration-are-related-to-selection-on-mhc-genes-in-birds
#17
Piotr Minias, Linda A Whittingham, Peter O Dunn
The Major Histocompatibility Complex (MHC) plays a key role in pathogen recognition as a part of vertebrate adaptive immune system. The great diversity of MHC genes in natural populations is maintained by different forms of balancing selection and its strength should correlate with the diversity of pathogens to which a population is exposed and the rate of exposure. Despite this prediction, little is known about how the life-history characteristics affect selection at the MHC. Here, we examined whether the strength of balancing selection on MHC class II genes in birds (as measured with nonsynonymous nucleotide substitutions, dN) was related to their social or migratory behaviour, two life-history characteristics correlated with pathogen exposure...
December 6, 2016: Evolution; International Journal of Organic Evolution
https://www.readbyqxmd.com/read/27921274/evaluating-determinants-of-rural-villagers-engagement-in-conservation-and-waste-management-behaviors-based-on-integrated-conceptual-framework-of-pro-environmental-behavior
#18
Piyapong Janmaimool, Chaweewan Denpaiboon
This study aims to evaluate determinants of villagers' engagement in pro-environmental behavior (PEB), including ecological conservation behavior (ECB) and waste management behavior (WMB). An integrated exploratory model representing the proposed relationship between villagers' engagement in ECB/WMB and their determinants was created based on the integration of the theory of planned behavior (TPB), the Stern's value belief norm (VBN) theory, environmental education and psychosocial characteristic perspectives...
December 2016: Life Sciences, Society and Policy
https://www.readbyqxmd.com/read/27921266/technology-based-blended-learning-to-facilitate-psychiatry-resident-training-in-prolonged-exposure-pe-therapy-for-ptsd
#19
Eric Kuhn, Emily Hugo
No abstract text is available yet for this article.
December 5, 2016: Academic Psychiatry
https://www.readbyqxmd.com/read/27921190/elearning-resources-to-supplement-postgraduate-neurosurgery-training
#20
Martin N Stienen, Karl Schaller, Hannah Cock, Vitalie Lisnic, Luca Regli, Simon Thomson
BACKGROUND: In an increasingly complex and competitive professional environment, improving methods to educate neurosurgical residents is key to ensure high-quality patient care. Electronic (e)Learning resources promise interactive knowledge acquisition. We set out to give a comprehensive overview on available eLearning resources that aim to improve postgraduate neurosurgical training and review the available literature. MATERIAL AND METHODS: A MEDLINE query was performed, using the search term "electronic AND learning AND neurosurgery"...
December 5, 2016: Acta Neurochirurgica
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