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https://www.readbyqxmd.com/read/28819065/effects-of-the-fort-mcmurray-wildfires-on-the-health-of-evacuated-workers-follow-up-of-2-cohorts
#1
Nicola Cherry, Whitney Haynes
BACKGROUND: Wildfire engulfed Fort McMurray, Alberta on May 3, 2016, leading to a total evacuation. Access to 2 active cohorts allowed us to rapidly assess health effects in those evacuated. METHODS: People working in Fort McMurray who had been recruited before the fire for 2 occupational health cohort studies completed a questionnaire (online or via telephone) 3-26 weeks after evacuation. The questionnaire asked about respiratory and mental health and experiences since the fire...
August 15, 2017: CMAJ Open
https://www.readbyqxmd.com/read/28818240/reducing-cancer-and-cancer-disparities-lessons-from-a-youth-generated-diabetes-prevention-campaign
#2
Dean Schillinger, Pamela M Ling, Sarah Fine, Cherrie B Boyer, Elizabeth Rogers, Roberto Ariel Vargas, Kirsten Bibbins-Domingo, Wen-Ying Sylvia Chou
Adolescence and young adulthood, a period essential for determining exposures over the life-course, is an ideal time to intervene to lower cancer risk. This demographic group can be viewed as both the target audience and generator of messages for cancer prevention, such as skin cancer, obesity-, tobacco-, and human papillomavirus-related cancers. The purpose of this paper is to encourage innovative health communications that target youth; youth behavior; and the structural, environmental, and social determinants of youth behavior as critical areas of focus for cancer prevention and disparities reduction...
September 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28816862/unilateral-optic-neuritis-and-central-retinal-vasculitis-due-to-ocular-syphilis
#3
Murtaza S Khan, Dulanji K Kuruppu, Tanav A Popli, Ramana S Moorthy, Devin D Mackay
PURPOSE: Report a case of concurrent unilateral optic neuritis and central retinal artery occlusion as the presenting signs of syphilis. METHODS: A case report of a 22-year-old man with progressive unilateral vision loss. RESULTS: With no known previous history of syphilis, genital lesions, or other extraocular manifestations, the patient presented with pain with eye movements and decreased color vision. His vision dramatically worsened after a course of oral steroids...
August 14, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28814647/substrate-triggered-position-switching-of-tata-and-tatb-during-tat-transport-in-escherichia-coli
#4
Johann Habersetzer, Kristoffer Moore, Jon Cherry, Grant Buchanan, Phillip J Stansfeld, Tracy Palmer
The twin-arginine protein transport (Tat) machinery mediates the translocation of folded proteins across the cytoplasmic membrane of prokaryotes and the thylakoid membrane of plant chloroplasts. The Escherichia coli Tat system comprises TatC and two additional sequence-related proteins, TatA and TatB. The active translocase is assembled on demand, with substrate-binding at a TatABC receptor complex triggering recruitment and assembly of multiple additional copies of TatA; however, the molecular interactions mediating translocase assembly are poorly understood...
August 2017: Open Biology
https://www.readbyqxmd.com/read/28813608/hot-air-treatment-induces-disease-resistance-through-activating-the-phenylpropanoid-metabolism-in-cherry-tomato-fruit
#5
Yingying Wei, Dandan Zhou, Jing Peng, Leiqing Pan, Kang Tu
To explore the effects of hot air (HA, 38 °C for 12 h) treatment on phenylpropanoid metabolism in cherry tomatoes, phenylpropanoid metabolite levels and the activities and expression of key enzymes were analyzed in HA-treated fruit. HA treatment enhanced phenylpropanoid metabolism, as evidenced by elevated levels of phenolics and flavonoids, higher activities of phenylalanine ammonia-lyase and cinnamate-4-hydroxylase, and up-regulated expression of LeCHS, LeCHI, LeF3H, and LeFLS. Levels of several phenylpropanoid metabolites were higher after HA treatment, including p-coumaric acid, caffeic acid, chlorogenic acid, isoquercitrin, quercetin, and rutin...
August 16, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28813424/risk-factors-and-causative-organisms-in-microbial-keratitis-in-daily-disposable-contact-lens-wear
#6
Fiona Stapleton, Thomas Naduvilath, Lisa Keay, Cherry Radford, John Dart, Katie Edwards, Nicole Carnt, Darwin Minassian, Brien Holden
PURPOSE: This study investigated independent risk factors and causative organisms in microbial keratitis in daily disposable contact lens (CL)-wearers. METHODS: A multisite prospective case-control study was undertaken. Cases were daily disposable CL-wearers attending Moorfields Eye Hospital with microbial keratitis and those reported through a one-year surveillance study in Australia and in New Zealand. A population-based telephone survey identified daily disposable CL-wearing controls...
2017: PloS One
https://www.readbyqxmd.com/read/28811118/prediction-and-characterization-of-the-stability-enhancing-effect-of-the-cherry-tag%C3%A2-in-highly-concentrated-protein-solutions-by-complex-rheological-measurements-and-md-simulations
#7
Pascal Baumann, Marie-Therese Schermeyer, Hannah Burghardt, Cathrin Dürr, Jonas Gärtner, Jürgen Hubbuch
Solution stability attributes are one of the key parameters within the production and launching phase of new biopharmaceuticals. Instabilities of active biological compounds can reduce the yield of biopharmaceutical productions, and may induce undesired reactions in patients, such as immunogenic rejections. Protein solution stability thus needs to be engineered and monitored throughout production and storage. In contrast to the gold standard of long-term storage experiments applied in industry, novel experimental and in silico molecular dynamics tools for predicting protein solution stability can be applied within several minutes or hours...
August 12, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28810665/determinants-of-full-vaccination-status-in-children-aged-12-23-months-in-gur%C3%A3-%C3%A3-and-milange-districts-mozambique-results-of-a-population-based-cross-sectional-survey
#8
Shellese A Shemwell, Meridith B Peratikos, Lázaro González-Calvo, Montse Renom-Llonch, Alexandre Boon, Samuel Martinho, Charlotte B Cherry, Ann F Green, Troy D Moon
Background: In 2011, 64% of children in Mozambique, ages 12-23 months, were fully immunized. Large provincial differences in vaccine uptake exist. Methods: We conducted a survey of 1650 females with children aged 12-23 months in the districts of Gurùé and Milange. Implementation occurred from November to December 2014. Descriptive statistics and logistic regression using R-software 3.0.2 were used to examine factors associated with full vaccination status. ArcGIS version 10...
July 1, 2017: International Health
https://www.readbyqxmd.com/read/28805610/validation-of-a-high-throughput-and-robust-technique-bacs-on-beads-assay-karyolite-bobs-for-pre-implantation-aneuploidy-screening
#9
Grace Wing Shan Kong, Yanlin Ma, Jian Ou, Yvonne Ka Yin Kwok, Wei Wang, Queenie Sum Yee Yeung, Cherry Kit Man Wong, Qi Li, Wen Xu, Weiying Lu, Hong Li, Tin Chiu Li, Kwong Wai Choy
OBJECTIVE: This study aims to validate the BACs-on-Beads (BoB) technology as a robust and high throughput method for pre-implantation genetic screening (PGS) for aneuploidy. MATERIAL AND METHODS: The performances with respect to the sensitivity, specificity, success rate and detection rate of this technique from new BoBs technology and traditional array chromosomal genomic hybridization (aCGH) were compared. And the use of BoBs as a screening tool for euploid embryos in PGS was evaluated...
August 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28802848/structure-and-intracellular-antioxidant-activity-of-pectic-polysaccharide-from-acerola-malpighia-emarginata
#10
Rafael Roberto Klosterhoff, Juliana Müller Bark, Nícolas Manzke Glänzel, Marcello Iacomini, Gláucia Regina Martinez, Sheila M B Winnischofer, Lucimara M C Cordeiro
Malpighia emarginata is a tropical fruit plant, found naturally in the Caribbean islands and South America that produces an edible fruit known as acerola or Barbados Cherry. Its polysaccharides were obtained by aqueous extraction, subjected to a freezing and thawing process and ultrafiltration. A homogeneous fraction (ACWS-01E) was analyzed by sugar composition, HPSEC, methylation and NMR spectroscopy analyses. The results showed an arabinan-rich pectic polysaccharide, with 6.1×10(4)g/mol and formed mainly by a high methyl esterified (DM=86%) homogalacturonan and branched arabinan...
August 9, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28800045/textual-synthesis-of-policies-and-guidance-statements-for-remote-healthcare-practitioners-on-managing-medical-emergencies-in-the-oil-and-gas-industry-a-systematic-review-protocol
#11
Kennedy A Osakwe, Kay Cooper, Derek Stewart, Cherry L Wainwright, Susan Klein
The objective of this review is to collate, synthesize and present the available evidence on the policies and guidance statements for remote healthcare practitioners on managing medical emergencies in the offshore oil and gas industry.More specifically, the review seeks to answer the following questions.
August 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/28798280/quenching-the-spark-termination-of-cicr-in-the-submicroscopic-space-of-the-dyad
#12
REVIEW
Mark B Cannell, Cherrie H T Kong
No abstract text is available yet for this article.
August 10, 2017: Journal of General Physiology
https://www.readbyqxmd.com/read/28796661/fms-like-tyrosine-kinase-3-ligand-attenuates-local-and-systemic-infection-in-a-model-of-post-burn-pneumonia
#13
Gabriel Hundeshagen, Weihua Cui, Lindsay Musgrove, Aaron Cherry, Seung-Jin Lee, Robert A Cox, Tracy Toliver-Kinsky
BACKGROUND: Burn injury induces immunosuppression and promotes infection with opportunistic pathogens. Pneumonia and sepsis are leading causes of post-burn morbidity and mortality. Fms-like tyrosine kinase-3 ligand (Flt3L) improves local and systemic resistance to P. aeruginosa-associated burn wound infection. This study evaluates the effects of post-burn prophylactic Flt3L treatment on local and systemic infection and inflammation in a murine model of pneumonia and sepsis. METHODS: Mice received a severe scald burn, were treated with Flt3L or vehicle (CTR) for 5 days and inoculated trans-nasally with P...
August 7, 2017: Shock
https://www.readbyqxmd.com/read/28790996/gene-replacement-and-fluorescent-labeling-to-study-the-functional-role-of-exopolysaccharides-in-bifidobacterium-animalis-subsp-lactis
#14
Nuria Castro-Bravo, Claudio Hidalgo-Cantabrana, Miguel A Rodriguez-Carvajal, Patricia Ruas-Madiedo, Abelardo Margolles
An extracellular layer of exopolysaccharides (EPS) covers the surface of some Bifidobacterium animalis subsp. lactis strains, which could be of relevance for its probiotic performance. In order to understand the functional characteristics of B. animalis subsp. lactis, two isogenic strains that differ in their EPS-producing phenotype, due to a single mutation in the gene Balat_1410, were studied. By means of a double crossover recombination strategy, successfully used for the first time in bifidobacteria, Balat_1410 in the type strain B...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28782352/cornus-mas-a-review-on-traditional-uses-and-pharmacological-properties
#15
Fatemeh Hosseinpour-Jaghdani, Tahoora Shomali, Sajedeh Gholipour-Shahraki, Mohammad Rahimi-Madiseh, Mahmoud Rafieian-Kopaei
Medicinal plants that are used today have been known by people of ancient cultures around the world and have largely been considered due to their medicinal properties. Cornus mas L. (Cornelian cherry) is one of these medicinal plants with high level of antioxidant activity. Cornelian cherry is an attractive ornamental plant with delicious fruit having nutritional and therapeutic values. The main purpose of this paper is to present and summarize the pharmacological and therapeutic effects from researches done on Cornelian cherry in studies from 2000 to 2016...
March 31, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28780496/fifteen-minute-consultation-a-structured-approach-to-the-management-of-chronic-cough-in-a-child
#16
Cherry Alviani, Gary Ruiz, Atul Gupta
Coughing is a primary pulmonary defence mechanism that enhances clearance of secretions and particles from the airways and protects against aspiration of foreign materials. Coughing may affect 30% of children at any given time (1). Many are healthy children but some may have serious underlying disease. Childhood cough accounts for a large number of consultations and 80% of families who are referred to a paediatric respiratory clinic for chronic cough have sought medical advice five times or more (2). The majority of childhood coughs are secondary to an acute respiratory tract infection and will improve once the infection resolves, usually within 1 to 3 weeks...
August 5, 2017: Archives of Disease in Childhood. Education and Practice Edition
https://www.readbyqxmd.com/read/28780489/developing-and-testing-a-comprehensive-tool-to-assess-family-meetings-empirical-distinctions-between-high-and-low-quality-meetings
#17
Courtenay R Bruce, Alana D Newell, Jonathan H Brewer, Divina O Timme, Evan Cherry, Justine Moore, Jennifer Carrettin, Emily Landeck, Rebecca Axline, Allison Millette, Ruth Taylor, Andrea Downey, Faisal Uddin, Deepa Gotur, Faisal Masud, Donna S Zhukovsky
BACKGROUND: The heterogeneity with regard to findings on family meetings (or conferences) suggests a need to better understand factors that influence family meetings. While earlier studies have explored frequency or timing of family meetings, little is known about how factors (such as what is said during meetings, how it is said, and by whom) influence family meeting quality. OBJECTIVES: (1) To develop an evaluation tool to assess family meetings (Phase 1); (2) to identify factors that influence meeting quality by evaluating 34 family meetings (Phase 2)...
July 28, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28780326/downregulation-of-inflammatory-cytokines-by-berberine-attenuates-riemerella-anatipestifer-infection-in-ducks
#18
Cherry P Fernandez, Fahmida Afrin, Rochelle A Flores, Woo H Kim, Jipseol Jeong, Suk Kim, Hong H Chang, Hyun S Lillehoj, Wongi Min
Riemerella anatipestifer, an important infectious bacterium affecting the duck industry, has 5-75% mortality, depending on strain virulence. We previously demonstrated that proinflammatory cytokines are involved in inflammation during, and regulating susceptibility to, R. anatipestifer infection. We investigated the effects of the anti-inflammatory compound berberine in duck splenic lymphocytes stimulated with killed R. anatipestifer, and in R. anatipestifer-infected ducks. IL-17A, IL-17F, and IL-1β transcripts were downregulated, and IFN-γ and IL-10 transcripts enhanced, in berberine-treated stimulated splenic lymphocytes, compared to stimulated untreated splenic lymphocytes...
August 2, 2017: Developmental and Comparative Immunology
https://www.readbyqxmd.com/read/28771112/cherry-picking-virginity-loss-definitions-among-gay-and-straight-cisgender-men
#19
Howard Huang
Virginity loss is a vital milestone in the development of one's sexual identity. Unfortunately, there is very little literature available studying virginity loss definitions among the wider straight population, and even less examining virginity loss among LGBTQ+ populations. The present study recruited 251 (45.4%) cisgender straight men and 114 (54.6%) cisgender gay men. An online, anonymous survey was administered to explore whether they considered various Male-on-Male (M-M) and Male-on-Female (M-F) sexual behaviors as constitutive of virginity loss...
August 3, 2017: Journal of Homosexuality
https://www.readbyqxmd.com/read/28770266/from-a-silane-monomer-to-anisotropic-buckled-silica-nanospheres-a-polymer-mediated-solvent-free-and-one-pot-synthesis
#20
Chih-Hui Lo, Teh-Min Hu
The morphology of particles, along with other particle attributes, has been shown to affect the biological fate of particles administered into the body. Particles with collapsed surfaces or shells (dimpled, buckled or crumpled) can have different appearances, under the microscope, that resemble many things encountered in our daily life, such as apples/cherries, doughnuts, and bowls. Recent studies have demonstrated that they are not just particles with interesting geometries, but they can also be used as functional blocks for assembled complex materials...
August 3, 2017: Soft Matter
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