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V S Yastrebov, V G Mitikhin, T A Solokhina, I A Mitikhina
AIM: Analysis and development of conceptual models of mental health organization allowing to determine the perspective directions of its further development. MATERIAL AND METHODS: The work was based on the collection of scientific publications on the problems of psychiatric care organization as well as the results of own research carried out by the authors over the last 25 years. System analysis was used for the development and analysis of the major conceptual models of mental health care...
2016: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
Jennifer M Buchman-Schmitt, Sarah J Brislin, Noah C Venables, Thomas E Joiner, Christopher J Patrick
BACKGROUND: The RDoC matrix framework calls for investigation of mental health problems through analysis of core biobehavioral processes quantified and studied across multiple domains of measurement. Critics have raised concerns about RDoC, including overemphasis on biological concepts/measures and disregard for the principle of multifinality, which holds that identical biological predispositions can give rise to differing behavioral outcomes. The current work illustrates an ontogenetic process approach to addressing these concerns, focusing on biobehavioral traits corresponding to RDoC constructs as predictors, and suicidal behavior as the outcome variable...
October 1, 2016: Journal of Affective Disorders
Mario Maj
No abstract text is available yet for this article.
October 2016: World Psychiatry: Official Journal of the World Psychiatric Association (WPA)
David M McCord, Margaret C Achee, Elissa M Cannon, Tiffany M Harrop, William D Poynter
The National Institute of Mental Health has proposed a paradigm shift in the conceptualization of psychopathology, abandoning the traditional categorical model in favor of one based on hierarchically organized dimensional constructs (Insel et al., 2010 ). One explicit goal of this initiative, the Research Domain Criteria (RDoC) project, is to facilitate the incorporation of newly available neurobiologic variables into research on psychopathology. The Minnesota Multiphasic Personality Inventory-2-Restructured Form (MMPI-2-RF; Ben-Porath & Tellegen, 2008/2011 ) represents a similar paradigm shift, also adopting a hierarchical arrangement of dimensional constructs...
October 7, 2016: Journal of Personality Assessment
Clay B Holroyd, Akina Umemoto
The United States National Institute of Mental Health has recently promoted the Research Domain Criteria framework, which emphasizes the study of neurocognitive constructs that cut across different disorders. These constructs are said to express dimensionally across the population, giving rise to psychopathologies only in the extreme cases where that expression is maladaptive. Inspired by the RDoC framework, we propose that recent insights into the function of anterior cingulate cortex (ACC), a brain area said to be responsible for selecting and motivating extended behaviors, may elucidate the etiology of a diverse array of mental disorders...
September 28, 2016: Neuroscience and Biobehavioral Reviews
Katharina Kircanski, Susan Zhang, Argyris Stringaris, Jillian Lee Wiggins, Kenneth E Towbin, Daniel S Pine, Ellen Leibenluft, Melissa A Brotman
BACKGROUND: By conceptualizing domains of behavior transdiagnostically, the National Institute of Mental Health Research Domain Criteria (NIMH RDoC) initiative facilitates new ways of studying psychiatric symptoms. In this study, latent profile analysis (LPA) was used to empirically derive classes or patterns of psychiatric symptoms in youth that transect traditional nosologic boundaries. METHODS: Data were drawn from 509 children and adolescents (ages 7-18 years; mean age =12...
September 21, 2016: Journal of Affective Disorders
D S Karhson, A Y Hardan, K J Parker
Core deficits in social functioning are associated with various neuropsychiatric and neurodevelopmental disorders, yet biomarker identification and the development of effective pharmacological interventions has been limited. Recent data suggest the intriguing possibility that endogenous cannabinoids, a class of lipid neuromodulators generally implicated in the regulation of neurotransmitter release, may contribute to species-typical social functioning. Systematic study of the endogenous cannabinoid signaling could, therefore, yield novel approaches to understand the neurobiological underpinnings of atypical social functioning...
2016: Translational Psychiatry
Huiting Liu, Lynne Lieberman, Elizabeth S Stevens, Randy P Auerbach, Stewart A Shankman
Asian Americans are one of the fastest growing minority groups in the United States; however, mental health within this population segment, particularly anxiety disorders, remains significantly understudied. Both the heterogeneity within the Asian American population and the multidimensional nature of anxiety contribute to difficulties in understanding anxiety in this population. The present paper reviewed two sources of heterogeneity within anxiety in Asian Americans: (1) cultural variables and (2) mechanisms or components of anxiety...
September 17, 2016: Journal of Anxiety Disorders
Amri Sabharwal, Akos Szekely, Roman Kotov, Prerona Mukherjee, Hoi-Chung Leung, Deanna M Barch, Aprajita Mohanty
Deficits in working memory (WM) and emotion processing are prominent impairments in psychotic disorders, and have been linked to reduced quality of life and real-world functioning. Translation of knowledge regarding the neural circuitry implementing these deficits into improved diagnosis and targeted treatments has been slow, possibly because of categorical definitions of disorders. Using the dimensional Research Domain Criteria (RDoC) framework, we investigated the clinical and practical utility of transdiagnostic behavioral and neural measures of emotion-related WM disruption across psychotic disorders...
October 2016: Journal of Abnormal Psychology
Carla Sharp, J Christopher Fowler, Ramiro Salas, David Nielsen, Jon Allen, John Oldham, Thomas Kosten, Sanjay Mathew, Alok Madan, B Christopher Frueh, Peter Fonagy
Recently, the National Institute of Mental Health (NIMH) introduced the Research Domain Criteria (RDoC) initiative to address two major challenges facing the field of psychiatry: (1) the lack of new effective personalized treatments for psychiatric disorders, and (2) the limitations associated with categorically defined psychiatric disorders. Although the potential of RDoC to revolutionize personalized psychiatric medicine and psychiatric nosology has been acknowledged, it is unclear how to implement RDoC in naturalistic clinical settings as part of routine outcomes research...
2016: Bulletin of the Menninger Clinic
(no author information available yet)
Reports an error in "Unreliability as a threat to understanding psychopathology: The cautionary tale of attentional bias" by Thomas L. Rodebaugh, Rachel B. Scullin, Julia K. Langer, David J. Dixon, Jonathan D. Huppert, Amit Bernstein, Ariel Zvielli and Eric J. Lenze (Journal of Abnormal Psychology, 2016[Aug], Vol 125[6], 840-851). There was an error in the Author Note concerning the support of the MacBrain Face Stimulus Set. The correct statement is provided. (The following abstract of the original article appeared in record 2016-30117-001...
October 2016: Journal of Abnormal Psychology
Erica Meyers, Mariah DeSerisy, Amy Krain Roy
In recent years, there has been much debate regarding the most appropriate diagnostic classification of children exhibiting emotion dysregulation in the form of irritability and severe temper outbursts. Most recently, this has resulted in the addition of a new diagnosis, Disruptive Mood Dysregulation Disorder (DMDD) in the DSM 5. The impetus for including this new disorder was to reduce the number of diagnoses that these children would typically receive; however, there is concern that it has only complicated matters rather than simplifying them...
August 13, 2016: Journal of Affective Disorders
Luc Faucher, Simon Goyer
The focus of the advocates of the Research Domain Critria (RDoC) on faulty brain circuits has led some to suspect it of being a reductionist enterprise. And because RDoC will eventually impact clinical psychiatry, some have feared that it will transform clinical psychiatry in a mindless and applied neurobehavioral science. We argue that if RDoC is officially endorsing a kind of reductionism, the particular kind of reductionism it endorses is not suffering from the shortcomings of more classical forms of reductionism...
December 2016: Revue de Synthèse
Claudio Sica, Gioia Bottesi, Corrado Caudek, Antonella Orsucci, Marta Ghisi
The heart of the obsessional process may be considered the subject's underlying impression that "something is wrong" or "that something is not just as it should be". This phenomenon, labeled "not just right experiences" (NJREs), has increasingly been receiving attention as a possible marker of obsessive-compulsive disorder (OCD). The present study sought to add to the evidence that NJREs may be a putative endophenotype of obsessional symptoms. To this aim, measures of NJREs, obsessive-compulsive (OC) symptoms and psychological distress were compared in offspring of parents with and without OC symptoms...
November 30, 2016: Psychiatry Research
Lauren M Bylsma, Iris B Mauss, Jonathan Rottenberg
This special section endeavors to facilitate the integration of biologically-based assessments of emotion into the clinical setting. This goal is consistent with the Research Domain Criteria (RDoC) initiative, which aims to identify transdiagnostic biobehavioral mechanisms that underlie mental disorders. We focus on four challenges to applying biologically-informed research on emotion and emotion regulation to clinical contexts: (1) How do we assess emotion in an RDoC framework? (2) How do we integrate measures of emotion with other systems in a wider context? (3) What do physiological indices of emotion tell us about clinical phenomena? and (4) How do we integrate physiological assessments into clinical practice? Throughout this comment, we refer to the articles in this special section to make our points, and, when possible, offer suggestions for future work to continue to address these challenges...
March 2016: Journal of Psychopathology and Behavioral Assessment
Katya C Fernandez, Hooria Jazaieri, James J Gross
It is widely agreed that emotion regulation plays an important role in many psychological disorders. We make the case that emotion regulation is in fact a key transdiagnostic factor, using the Research Domain Criteria (RDoC) as an organizing framework. In particular, we first consider how transdiagnostic and RDoC approaches have extended categorical views. Next, we examine links among emotion generation, emotion regulation, and psychopathology, with particular attention to key emotion regulation stages including identification, strategy selection, implementation, and monitoring...
June 2016: Cognitive Therapy and Research
J M Ellingson, L S Richmond-Rakerd, D J Statham, N G Martin, W S Slutske
BACKGROUND: Mental health disorders commonly co-occur, even between conceptually distinct syndromes, such as internalizing and externalizing disorders. The current study investigated whether phenotypic, genetic, and environmental variance in negative emotionality and behavioral control account for the covariation between major depressive disorder (MDD) and alcohol use disorder (AUD). METHOD: A total of 3623 members of a national twin registry were administered structured diagnostic telephone interviews that included assessments of lifetime histories of MDD and AUD, and were mailed self-report personality questionnaires that assessed stress reactivity (SR) and behavioral control (CON)...
October 2016: Psychological Medicine
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