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https://www.readbyqxmd.com/read/29168832/diagnostics-missing-the-point
#1
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No abstract text is available yet for this article.
November 23, 2017: Nature
https://www.readbyqxmd.com/read/29168772/a-survey-of-recent-advances-in-particle-filters-and-remaining-challenges-for-multitarget-tracking
#2
REVIEW
Xuedong Wang, Tiancheng Li, Shudong Sun, Juan M Corchado
We review some advances of the particle filtering (PF) algorithm that have been achieved in the last decade in the context of target tracking, with regard to either a single target or multiple targets in the presence of false or missing data. The first part of our review is on remarkable achievements that have been made for the single-target PF from several aspects including importance proposal, computing efficiency, particle degeneracy/impoverishment and constrained/multi-modal systems. The second part of our review is on analyzing the intractable challenges raised within the general multitarget (multi-sensor) tracking due to random target birth and termination, false alarm, misdetection, measurement-to-track (M2T) uncertainty and track uncertainty...
November 23, 2017: Sensors
https://www.readbyqxmd.com/read/29168691/a-recombinant-bbsome-core-complex-and-how-it-interacts-with-ciliary-cargo
#3
Björn Udo Klink, Eldar Zent, Puneet Juneja, Anne Kuhlee, Stefan Raunser, Alfred Wittinghofer
Cilia are small, antenna-like structures on the surface of eukaryotic cells that harbor a unique set of sensory proteins, including GPCRs and other membrane proteins. The transport of these proteins involves the BBSome, an eight-membered protein complex that is recruited to ciliary membranes by the G-protein Arl6. BBSome malfunction leads to Bardet-Biedl syndrome, a ciliopathy with severe consequences. Short ciliary targeting sequences (CTS) have been identified that trigger the transport of ciliary proteins...
November 15, 2017: ELife
https://www.readbyqxmd.com/read/29168573/oral-health-status-among-children-and-adolescents-in-governmental-and-private-schools-of-the-palestinian-territories
#4
Lamis Abuhaloob, Poul Erik Petersen
BACKGROUND: Political conflicts in the Palestinian Territories (PT) have resulted in systematic deterioration of socio-economic conditions and health. The World Health Organization (WHO) has emphasised the negative impacts of social crisis on children' oral health and quality of life. OBJECTIVES: To assess the prevalence and trends in dental caries and poor gingival health of schoolchildren in the PT through the scholastic years 1998/1999 to 2012/2013. METHODS: This is a retrospective study...
November 23, 2017: International Dental Journal
https://www.readbyqxmd.com/read/29168526/how-the-toxicity-of-nanomaterials-towards-different-species-could-be-simultaneously-evaluated-a-novel-multi-nano-read-across-approach
#5
Natalia Sizochenko, Alicja Mikolajczyk, Karolina Jagiello, Tomasz Puzyn, Jerzy Leszczynski, Bakhtiyor Rasulev
Application of predictive modeling approaches can solve the problem of missing data. Numerous studies have investigated the effects of missing values on qualitative or quantitative modeling, but only a few studies have discussed it for the case of applications in nanotechnology-related data. The present study is aimed at the development of a multi-nano-read-across modeling technique that helps in predicting the toxicity of different species such as bacteria, algae, protozoa, and mammalian cell lines. Herein, the experimental toxicity of 184 metal and silica oxide (30 unique chemical types) nanoparticles from 15 datasets is analyzed...
November 23, 2017: Nanoscale
https://www.readbyqxmd.com/read/29168507/orthogonal-muscle-fibres-have-different-instructive-roles-in-planarian-regeneration
#6
M Lucila Scimone, Lauren E Cote, Peter W Reddien
The ability to regenerate missing body parts exists throughout the animal kingdom. Positional information is crucial for regeneration, but how it is harboured and used by differentiated tissues is poorly understood. In planarians, positional information has been identified from study of phenotypes caused by RNA interference in which the wrong tissues are regenerated. For example, inhibition of the Wnt signalling pathway leads to regeneration of heads in place of tails. Characterization of these phenotypes has led to the identification of position control genes (PCGs)-genes that are expressed in a constitutive and regional manner and are associated with patterning...
November 22, 2017: Nature
https://www.readbyqxmd.com/read/29168394/documentation-of-child-maltreatment-in-electronic-health-records
#7
Canan Karatekin, Brandon Almy, Susan Marshall Mason, Iris Borowsky, Andrew Barnes
International Classification of Diseases codes for child maltreatment can aid surveillance and research, but the extent to which they are used is not well established. We documented prevalence of the use of maltreatment-related codes, examined demographic characteristics of youth assigned these codes, and compared results with previous studies. Data were extracted from electronic health records of 0- to 21-year-olds assigned 1 of 15 maltreatment-related International Classification of Diseases, Ninth Revision, codes who had encounters in a large medical system over a 4-year period...
November 1, 2017: Clinical Pediatrics
https://www.readbyqxmd.com/read/29168352/patient-satisfaction-with-information-on-oral-anticancer-agent-use
#8
Christel C L M Boons, Lonneke Timmers, Natasja M van Schoor, Eleonora L Swart, N Harry Hendrikse, Jeroen J W M Janssen, Jacqueline G Hugtenburg
Adequate information on oral anticancer agent (OACA) use is an essential element of optimal cancer care. The present study aimed to get insight into the experiences of patients with information on OACA treatment and their characteristics regarding information dissatisfaction. Patients of four Dutch university hospitals using OACA participated in this observational study and completed the Satisfaction with Information about Medicines Scale (SIMS), EORTC Quality of Life Questionnaire-C30, Brief Illness Perception Questionnaire, and Beliefs about Medicines Questionnaire-Specific...
November 23, 2017: Cancer Medicine
https://www.readbyqxmd.com/read/29168326/guidelines-in-charge-syndrome-and-the-missing-link-cranial-imaging
#9
REVIEW
Christa M de Geus, Rolien H Free, Berit M Verbist, Deborah A Sival, Kim D Blake, Linda C Meiners, Conny M A van Ravenswaaij-Arts
"CHARGE syndrome" is a complex syndrome with high and extremely variable comorbidity. As a result, clinicians may struggle to provide accurate and comprehensive care, and this has led to the publication of several clinical surveillance guidelines and recommendations for CHARGE syndrome, based on both single case observations and cohort studies. Here we perform a structured literature review to examine all the existing advice. Our findings provide additional support for the validity of the recently published Trider checklist...
November 23, 2017: American Journal of Medical Genetics. Part C, Seminars in Medical Genetics
https://www.readbyqxmd.com/read/29168291/the-col5a3-and-mmp9-genes-interact-in-eczema-susceptibility
#10
Patricia Margaritte-Jeannin, Marie-Claude Babron, Catherine Laprise, Nolwenn Lavielle, Chloé Sarnowski, Myriam Brossard, Miriam Moffatt, Valérie Gagné-Ouellet, Adrien Etcheto, Mark Lathrop, Jocelyne Just, William O Cookson, Emmanuelle Bouzigon, Florence Demenais, Marie-Hélène Dizier
BACKGROUND: Genetic studies of eczema have identified many genes, which explain only 14% of the heritability. Missing heritability may be partly due to ignored Gene-Gene (G-G) interactions. OBJECTIVE: Our aim was to detect new interacting genes involved in eczema. METHODS: The search for G-G interaction in eczema was conducted using a two-step approach, which included as a first step, a biological selection of genes, which are involved either in the skin or epidermis development or in the collagen metabolism, and as a second-step, an interaction analysis of the selected genes...
November 23, 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29168192/seeing-it-differently-self-reported-description-of-vision-loss-in-dry-age-related-macular-degeneration
#11
Deanna J Taylor, Laura A Edwards, Alison M Binns, David P Crabb
PURPOSE: A realistic description of visual symptoms associated with dry age-related macular degeneration (AMD) is important for raising awareness of the condition and educating patients. This study aimed to develop a set of descriptors for dry AMD and examine the realism of images currently and frequently used to show visual symptoms of the condition. METHODS: Volunteers with dry AMD with a range of disease severity were given an eye examination and were asked to describe visual symptoms of their condition in a conversational interview...
November 23, 2017: Ophthalmic & Physiological Optics: the Journal of the British College of Ophthalmic Opticians (Optometrists)
https://www.readbyqxmd.com/read/29168054/cardiac-function-in-patients-with-polymyositis-or-dermatomyositis-a-three-dimensional-speckle-tracking-echocardiography-study
#12
Yue Zhong, Wenjuan Bai, Qibing Xie, Jianhong Sun, Hong Tang, Li Rao
Cardiac event is a major cause of death in patients with idiopathic inflammatory myopathies (IIM). The most frequent IIMs are polymyositis (PM) and dermatomyositis (DM). The purpose of this study was to analyze cardiac involvement by three-dimensional speckle-tracking echocardiography (3D STE) in patients with PM or DM, and to identify the relationship of cardiac injury with clinical characteristics and disease-specific parameters. 60 PM/DM patients with preserved left ventricular ejection fraction and 30 matched healthy controls were assessed by conventional echocardiography, 3D STE with biventricular strain analysis and electrocardiogram...
November 22, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29167974/long-term-outcome-of-vaginal-mesh-or-native-tissue-in-recurrent-prolapse-a-randomized-controlled-trial
#13
Alfredo L Milani, Anne Damoiseaux, Joanna IntHout, Kirsten B Kluivers, Mariella I J Withagen
INTRODUCTION AND HYPOTHESIS: Our aim was to evaluate clinically relevant long-term outcomes of transvaginal mesh or native tissue repair in women with recurrent pelvic organ prolapse (POP). METHODS: We performed a 7-year follow-up of a randomized controlled trial on trocar-guided mesh placement or native tissue repair in women with recurrent POP. Primary outcome was composite success, defined as absence of POP beyond the hymen, absence of bulge symptoms, and absence of retreatment for POP...
November 22, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/29167927/new-diagnostic-criteria-for-gestational-diabetes-mellitus-and-their-impact-on-the-number-of-diagnoses-and-pregnancy-outcomes
#14
Sarah H Koning, Jelmer J van Zanden, Klaas Hoogenberg, Helen L Lutgers, Alberdina W Klomp, Fleurisca J Korteweg, Aren J van Loon, Bruce H R Wolffenbuttel, Paul P van den Berg
AIMS/HYPOTHESIS: Detection and management of gestational diabetes mellitus (GDM) are crucial to reduce the risk of pregnancy-related complications for both mother and child. In 2013, the WHO adopted new diagnostic criteria for GDM to improve pregnancy outcomes. However, the evidence supporting these criteria is limited. Consequently, these new criteria have not yet been endorsed in the Netherlands. The aim of this study was to determine the impact of these criteria on the number of GDM diagnoses and pregnancy outcomes...
November 22, 2017: Diabetologia
https://www.readbyqxmd.com/read/29167922/correction-to-anaerobic-benzene-mineralization-by-nitrate-reducing-and-sulfate-reducing-microbial-consortia-enriched-from-the-same-site-comparison-of-community-composition-and-degradation-characteristics
#15
Andreas H Keller, Sabine Kleinsteuber, Carsten Vogt
The original version of this article unfortunately contained mistakes in Table 1. The two data sets were accidentally missing in the table. The original article has been corrected.
November 22, 2017: Microbial Ecology
https://www.readbyqxmd.com/read/29167709/trends-over-time-in-dental-caries-status-in-urban-and-rural-thai-children
#16
Patcharawan Srisilapanan, Areerat Nirunsittirat, Jeffrey Roseman
Background: Historically, the prevalence of dental caries was higher in urban areas than rural areas of Thailand. This study aim to examine the time trends in caries status in children in Thailand. Material and Methods: Linear regression was used to examine trend of dental caries prevalence and mean number of teeth with caries, filled and missing due to caries (dmft/DMFT) in urban and rural, of 3-, 5-6 and 12-year olds from seven Thailand National Oral Health Surveys conducted approximately every 5 years from 1977 to 2012...
October 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/29167657/choices-regarding-thrombolysis-are-modified-by-the-way-to-transfer-the-messages
#17
Jingjing Gong, Yan Zhang, Hongyan Gao, Wei Wei, Jing Lv, Hongyun Liu, Yonghua Huang
Although thrombolysis is the most effective medical treatment for acute ischemic stroke, many stroke patients eligible for thrombolysis miss this treatment as a result of delay or refusal by the patients and/or their proxies. To explore the influences of prognostic information for different intervals from stroke onset to the start of thrombolytic treatment (OTT) and other factors on the preferences of patients/proxies regarding thrombolytic therapy, a cross-sectional, discrete-choice experiment was performed between August 2013 and September 2014...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29167653/what-drives-them-to-drive-parents-reasons-for-choosing-the-car-to-take-their-children-to-school
#18
Jessica Westman, Margareta Friman, Lars E Olsson
Children's school journeys have changed vastly during recent decades: More children are being driven to school in private cars instead of walking and cycling, with many who are entitled to a free school bus service still being driven. Earlier research into travel mode choice has often investigated how urban form impacts upon mode choice regarding school journeys-in particular how urban form hinders or enables the use of the active mode. This paper quantitatively explores parents' stated reasons for choosing the car and the relationship between these reasons and the decision to use the car to take their children to school...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29167627/the-importance-of-human-population-characteristics-in-modeling-aedes-aegypti-distributions-and-assessing-risk-of-mosquito-borne-infectious-diseases
#19
Julie F Obenauer, T Andrew Joyner, Joseph B Harris
Background: The mosquito Aedes aegypti has long been a vector for human illness in the Southeastern United States. In the past, it has been responsible for outbreaks of dengue, chikungunya, and yellow fever and, very recently, the Zika virus that has been introduced to the region. Multiple studies have modeled the geographic distribution of Ae. aegypti as a function of climate factors; however, this ignores the importance of humans to the anthropophilic biter. Furthermore, Ae. aegypti thrives in areas where humans have created standing water sites, such as water storage containers and trash...
2017: Tropical Medicine and Health
https://www.readbyqxmd.com/read/29167528/mercury-evasion-from-a-boreal-peatland-shortens-the-timeline-for-recovery-from-legacy-pollution
#20
Stefan Osterwalder, Kevin Bishop, Christine Alewell, Johannes Fritsche, Hjalmar Laudon, Staffan Åkerblom, Mats B Nilsson
Peatlands are a major source of methylmercury that contaminates downstream aquatic food webs. The large store of mercury (Hg) in peatlands could be a source of Hg for over a century even if deposition is dramatically reduced. However, the reliability of Hg mass balances can be questioned due to missing long-term land-atmosphere flux measurements. We used a novel micrometeorological system for continuous measurement of Hg peatland-atmosphere exchange to derive the first annual Hg budget for a peatland. The evasion of Hg (9...
November 22, 2017: Scientific Reports
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