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https://www.readbyqxmd.com/read/29793099/carbon-monoxide-analysis-method-in-human-blood-by-airtight-gas-syringe-gas-chromatography-mass-spectrometry-ags-gc-ms-relevance-for-postmortem-poisoning-diagnosis
#1
S Oliverio, V Varlet
Carbon monoxide is one of the most abundant toxic air pollutants. Symptoms of a CO intoxication are non-specific, leading to a high number of misdiagnosed CO poisoning cases that are missing in the disease statistics. The chemical nature of the molecule makes it difficult to detect for long periods and at low levels, thus requiring a very accurate and sensitive method. Current methods capable of accurate and sensitive analyses are available, however an inconsistency between results and symptoms are frequently reported...
May 18, 2018: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/29793009/evidence-on-the-measurement-properties-of-health-related-quality-of-life-instruments-is-largely-missing-in-patients-with-low-back-pain-a-systematic-review
#2
REVIEW
Alessandro Chiarotto, Caroline B Terwee, Steven J Kamper, Maarten Boers, Raymond W Ostelo
OBJECTIVE: To synthesize the measurement properties of five health-related quality of life (HRQoL) instruments [Short Form 36 (SF-36), Short Form 12 (SF-12), EuroQol 5D (EQ-5D), Nottingham Health Profile (NHP), PROMIS Global Health (PROMIS-GH-10)] in patients with low back pain (LBP). STUDY DESIGN AND SETTING: Six electronic databases (MEDLINE, EMBASE, CINAHL, PsycINFO, SportDiscus, Google Scholar) were searched (July 2017). Studies assessing any measurement property in non-specific LBP patients were included...
May 21, 2018: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/29792998/bmi-and-gender-increase-risk-for-sacral-fractures-after-multilevel-instrumented-spinal-fusion-compared-to-bone-mineral-density-and-pelvic-parameters
#3
Stephan N Salzmann, Courtney Ortiz Miller, John A Carrino, Jingyan Yang, Jennifer Shue, Andrew A Sama, Frank P Cammisa, Federico P Girardi, Alexander P Hughes
BACKGROUND CONTEXT: Sacral fractures are a rare but potentially devastating complication. Long-fusion constructs including the sacrum that do not extend to the pelvis may result in sacral fractures. Besides established risk factors including gender, age and number of levels fused, body mass index (BMI), pelvic parameters and bone mineral density (BMD) have also been proposed as potential risk factors for postoperative sacral fractures. The literature supporting this, however, is limited...
May 21, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29792910/perception-of-children-with-visible-untreated-and-treated-caries
#4
Claudia Tschammler, David Zimmermann, Sarah Batschkus, Annette Wiegand, Kristian Folta-Schoofs
OBJECTIVES: This study aimed to analyse if children with untreated or treated caries (restorations/missing teeth) are perceived differently compared to children with healthy teeth and to explore possible differences in the perception by laypersons and dental experts. METHODS: Eye movements of female experts (n = 20) and laypersons (n = 18) were recorded by eye-tracking while paired images (neutral expression/teeth not visible; emotional expression/smiling, teeth visible) of children with healthy teeth, with visible untreated or treated caries (restorations/missing teeth as a consequence of caries treatment), each n = 13, were presented...
May 21, 2018: Journal of Dentistry
https://www.readbyqxmd.com/read/29792727/added-value-of-including-entire-brain-on-body-imaging-with-fdg-pet-mri
#5
Ana M Franceschi, Robert Matthews, Lev Bangiyev, Nand Relan, Ammar Chaudhry, Dinko Franceschi
OBJECTIVE: FDG PET/MRI examination of the body is routinely performed from the skull base to the mid thigh. Many types of brain abnormalities potentially could be detected on PET/MRI if the head was included. The objective of this study was therefore to identify and characterize brain findings incidentally detected on PET/MRI of the body with the head included. MATERIALS AND METHODS: We retrospectively identified 269 patients with FDG PET/MRI whole-body scans that included the head...
May 24, 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29792095/what-is-the-effect-of-intertwin-delivery-interval-on-the-outcome-of-the-second-twin-delivered-vaginally
#6
Paola Algeri, Clelia Callegari, Salvatore Andrea Mastrolia, Letizia Brienza, Isadora Vaglio Tessitore, Giuseppe Paterlini, Maddalena Incerti, Sabrina Cozzolino, PatriziaVergani
OBJECTIVE: Optimal management of twin deliveries is controversial. We aimed to assess if intertwin delivery interval, after vaginal delivery of the first twin, may have an influence on adverse neonatal outcomes of the second twin Study design: This is a retrospective observational study including diamniotic twin pregnancies with vaginal delivery of the first twin, between January 2000 and July 2017. Inclusion criteria were diamniotic pregnancies and vaginal delivery of the first twin...
May 23, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29792066/capabilities-of-next-generation-patch-pump-improved-precision-instant-occlusion-detection-and-dual-hormone-therapy
#7
Forrest W Payne, Bradley Ledden, Greg Lamps
Insulin pumps allow patients to attain better blood glucose control with more lifestyle flexibility. Their size and cost, however, limit their usefulness. Current CSII pumps are bulky, intrusive, and expensive. SFC Fluidics is addressing these problems by developing a new type of wearable patch pump based on the patented electro-chemiosmotic (ECO) microfluidic pumping technology. This nonmechanical pumping technology allows accurate and precise delivery of very small amounts of insulin and/or other drugs, including concentrated insulin...
May 1, 2018: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29792044/annals-express-an-assessment-of-the-effect-of-haemoglobin-variants-on-detection-by-faecal-immunochemical-tests
#8
Magdalen Romany Rowan Carroll, Cerin John, Debbie Mantio, Natasha Djedovic, Sally C Benton
BACKGROUND: Faecal immunochemical tests (FIT) for haemoglobin (Hb) are being used in the investigation of colorectal cancer. These tests use antibodies raised to the globin moiety of human Hb. Where the globin structure is abnormal or reduced, it is possible that antibody binding, and thus Hb-detection may be affected. METHODS: Lysates prepared from whole blood samples of patients with known variants, were diluted in manufacturer specific buffer to 10, 100, and 500 µg Hb/g faeces...
January 1, 2018: Annals of Clinical Biochemistry
https://www.readbyqxmd.com/read/29792041/increased-diagnostic-confidence-in-the-diagnosis-of-pituitary-micro-lesions-with-the-addition-of-three-dimensional-sampling-perfection-with-application-optimized-contrasts-using-different-flip-angle-evolutions-sequences
#9
Ying Tang, Yue Wu, Hua Zhang, Jing Wang, ZhenWei Yao
Background Conventional magnetic resonance imaging (MRI) is adversely affected by thick slices, small intersection gaps, and the partial volume effect, leading to the missed diagnosis or misdiagnosis of pituitary micro-lesions. Purpose To evaluate the diagnostic yield of three-dimensional sampling perfection with application-optimized contrasts using different flip-angle evolutions (3D-T2 SPACE) sequences compared with a standard MRI protocol for the diagnosis of pituitary micro-lesions. Material and Methods The MRI findings of 664 patients with clinically suspected pituitary lesions were retrospectively analyzed...
January 1, 2018: Acta Radiologica
https://www.readbyqxmd.com/read/29791812/automated-oestrus-detection-using-multimetric-behaviour-recognition-in-seasonal-calving-dairy-cattle-on-pasture
#10
J Brassel, F Rohrssen, K Failing, A Wehrend
AIM: To evaluate the performance of a novel accelerometer-based oestrus detection system (ODS) for dairy cows on pasture, in comparison with measurement of concentrations of progesterone in milk, ultrasonographic examination of ovaries and farmer observations. METHODS: Mixed-breed lactating dairy cows (n=109) in a commercial, seasonal-calving herd managed at pasture under typical farming conditions in Ireland, were fitted with oestrus detection collars 3 weeks prior to mating start date...
May 23, 2018: New Zealand Veterinary Journal
https://www.readbyqxmd.com/read/29791802/the-power-of-shielding-low-toxicity-and-high-transfection-performance-of-cationic-graft-copolymers-containing-poly-2-oxazoline-side-chains
#11
Anne-Kristin Trützschler, Tanja Bus, Martin Sahn, Anja Traeger, Christine Weber, Ulrich S Schubert
In this study we show the potential of oligo(2-ethyl-2-oxazoline) (OEtOx) shielded graft copolymers of (2 aminoethyl)-methacrylate (AEMA) and N methyl (2-aminoethyl) methacrylate (MAEMA) for pDNA delivery in HEK cells. Copolymers were synthesized via the macromonomer method using a combination of cationic ring opening polymerization (CROP) and reversible addition-fragmentation chain transfer (RAFT) polymerization to vary the degree of grafting (DG = 10% and 30%) as well as the side chain degree of polymerization (DP = 5 and 20)...
May 23, 2018: Biomacromolecules
https://www.readbyqxmd.com/read/29791753/double-jeopardy-missed-care-for-the-vulnerable-in-community-settings
#12
EDITORIAL
Annamaria Bagnasco, Fiona Timmins, Giuseppe Aleo, Loredana Sasso
Inequitable access of the world's population to quality health services is still a problem, despite the fact that good health and wellbeing are recognised as a fundamental human rights (United Nations, 2016). Reducing inequities in health is a major focus of international policy (World Health Organisation, 2015) and in the context of an ever-aging population, world recession, limited resources, and to promote independence in health, community care schemes are gaining increasing popularity (Phelan et al 2017)...
May 23, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29791692/prosthetic-orthodontic-and-implant-supported-rehabilitation-of-five-maxillary-anterior-teeth-with-alveolar-bone-loss
#13
Odilon Guariza-Filho, Cristiano Miranda de Araujo, Angela Graciela Deliga Schroder, Orlando Motohiro Tanaka, Ricardo Kern, Antonio Carlos Ruellas
INTRODUCTION: Treatment of maxillofacial injuries is complex and requires the establishment of a comprehensive and accurate diagnosis and correct treatment planning. OBJECTIVE: The objective of this case report was to describe the re-treatment of a 27-year-old woman who was involved in a severe car accident that resulted in the loss of five anterior teeth and alveolar bone, and whose previous orthodontic and surgical treatments had been unsuccessful. CASE REPORT: In this case, the space for the missing mandibular molar was reopened to allow for rehabilitation...
January 2018: Dental Press Journal of Orthodontics
https://www.readbyqxmd.com/read/29791495/early-prediction-of-contrast-induced-acute-kidney-injury-by-a-bedside-assessment-of-neutrophil-gelatinase-associated-lipocalin-during-elective-percutaneous-coronary-interventions
#14
Annunziata Nusca, Marco Miglionico, Claudio Proscia, Laura Ragni, Massimiliano Carassiti, Francesca Lassandro Pepe, Germano Di Sciascio
Contrast-induced acute kidney injury (CI-AKI) is a serious complication during percutaneous coronary interventions (PCI). Currently, the diagnosis of CI-AKI relies on serum creatinine (SCr) that is however affected by several limitations potentially leading to delayed or missed diagnoses. In this study we examined the diagnostic accuracy of a "bedside" measurement of plasma Neutrophil Gelatinase-Associated Lipocalin (NGAL) in the early detection of CI-AKI in 97 patients undergoing elective PCI. The overall incidence of CI-AKI was 3%...
2018: PloS One
https://www.readbyqxmd.com/read/29791391/effects-of-aberrations-on-effective-point-spread-function-in-sted-microscopy
#15
Yanghui Li, Hui Zhou, Xiaoyu Liu, Yuxue Li, Le Wang
Like other imaging techniques, stimulated emission depletion (STED) microscopy suffers from aberrations. While their effects on depletion patterns have been explicitly investigated, the study on how aberrations affect the effective point spread function (PSF) in STED microscopy is still missing. For STED researchers, however, this study is beneficial, as it directly bridges image qualities and aberrations. In this paper, we quantitatively analyze the effects of primary aberrations, including astigmatism, coma, trefoil, and spherical aberration, in two-dimensional (2D) and three-dimensional (3D) STED microscopy, and further discuss the corresponding aberration tolerance...
May 20, 2018: Applied Optics
https://www.readbyqxmd.com/read/29791279/loneliness-in-senior-housing-communities
#16
Harry Owen Taylor, Yi Wang, Nancy Morrow-Howell
There are many studies on loneliness among community-dwelling older adults; however, there is limited research examining the extent and correlates of loneliness among older adults who reside in senior housing communities. This study examines the extent and correlates of loneliness in three public senior housing communities in the St. Louis area. Data for this project was collected with survey questionnaires with a total sample size of 148 respondents. Loneliness was measured using the Hughes 3-item loneliness scale...
May 23, 2018: Journal of Gerontological Social Work
https://www.readbyqxmd.com/read/29791009/withdrawn-interventions-for-replacing-missing-teeth-1-versus-2-stage-implant-placement
#17
REVIEW
Marco Esposito, Maria Gabriella Grusovin, Yun Shane Chew, Paul Coulthard, Helen V Worthington
BACKGROUND: Implants may be placed penetrating the oral mucosa (1-stage procedure) or can be completely buried under the oral mucosa (2-stage procedure) during the healing phase of the bone at the implant surface. With a 2-stage procedure the risk of having unwanted loading onto the implants is minimized, but a second minor surgical intervention is needed to connect the healing abutments and more time is needed prior to start the prosthetic phase because of the wound-healing period required in relation to the second surgical intervention...
May 23, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29790923/missed-opportunities-to-prescribe-preexposure-prophylaxis-in-south-carolina-2013-2016
#18
Dawn K Smith, Man-Huei Chang, Wayne A Duffus, Stella Okoye, Sharon Weissman
Introduction: Expanding use of preexposure prophylaxis (PrEP) in ways that address current racial/ethnic disparities is an important HIV prevention goal. We investigated missed opportunities to provide PrEP during healthcare visits occurring prior to HIV infection. Methods: This retrospective cohort study linked South Carolina HIV case surveillance data to 3 statewide healthcare databases. Characteristics of patients, health care visits and providers, sexually transmitted diseases (STD), and other diagnoses, were assessed for medical encounters occurring before an initial HIV diagnosis...
May 22, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29790911/panda-view-an-easy-to-use-tool-for-statistical-analysis-and-visualization-of-quantitative-proteomics-data
#19
Cheng Chang, Kaikun Xu, Chaoping Guo, Jinxia Wang, Qi Yan, Jian Zhang, Fuchu He, Yunping Zhu
Summary: Compared with the numerous software tools developed for identification and quantification of -omics data, there remains a lack of suitable tools for both downstream analysis and data visualization. To help researchers better understand the biological meanings in their -omics data, we present an easy-to-use tool, named PANDA-view, for both statistical analysis and visualization of quantitative proteomics data and other -omics data. PANDA-view contains various kinds of analysis methods such as normalization, missing value imputation, statistical tests, clustering and principal component analysis, as well as the most commonly-used data visualization methods including an interactive volcano plot...
May 22, 2018: Bioinformatics
https://www.readbyqxmd.com/read/29790870/genetic-disorders-and-mortality-in-infancy-and-early-childhood-delayed-diagnoses-and-missed-opportunities
#20
Monica H Wojcik, Talia S Schwartz, Inbar Yamin, Heather L Edward, Casie A Genetti, Meghan C Towne, Pankaj B Agrawal
PurposeInfants admitted to a level IV neonatal intensive care unit (NICU) who do not survive early childhood are a population that is probably enriched for rare genetic disease; we therefore characterized their genetic diagnostic evaluation.MethodsThis is a retrospective analysis of infants admitted to our NICU between 1 January 2011 and 31 December 2015 who were deceased at the time of records review, with age at death less than 5 years.ResultsA total of 2,670 infants were admitted; 170 later died. One hundred six of 170 (62%) had an evaluation for a genetic or metabolic disorder...
April 12, 2018: Genetics in Medicine: Official Journal of the American College of Medical Genetics
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