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Inappropriate prescribing

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https://www.readbyqxmd.com/read/28064169/potentially-inappropriate-medication-prescribing-is-associated-with-socioeconomic-factors-a-spatial-analysis-in-the-french-nord-pas-de-calais-region
#1
Jean-Baptiste Beuscart, Michael Genin, Corrine Dupont, David Verloop, Alain Duhamel, Marguerite-Marie Defebvre, François Puisieux
BACKGROUND: potentially inappropriate medication (PIM) prescribing is common in older people and leads to adverse events and hospital admissions. OBJECTIVE: to determine whether prevalence of PIM prescribing varies according to healthcare supply and socioeconomic status. METHODS: all prescriptions dispensed at community pharmacies for patients aged 75 and older between 1 January  and 31 March 2012 were retrieved from French Health Insurance Information System of the Nord-Pas-de-Calais Region for patients affiliated to the Social Security scheme...
January 6, 2017: Age and Ageing
https://www.readbyqxmd.com/read/28064167/potentially-inappropriate-prescribing-to-older-patients-in-primary-care-in-the-netherlands-a-retrospective-longitudinal-study
#2
Linette Bruin-Huisman, Ameen Abu-Hanna, Henk C P M van Weert, Erna Beers
BACKGROUND: potentially inappropriate prescribing (PIP) is associated with adverse health effects in older patients. PIP comprises prescription of potentially inappropriate medications (PIMs) and potential prescribing omissions (PPOs). OBJECTIVE: to estimate the prevalence of PIMs and PPOs among older patients in primary care. DESIGN: retrospective longitudinal study. SETTING: routinely collected data of 182,000 patients of 49 general practitioners (GPs) gathered in the GPs' database of the Academic Medical Center of Amsterdam, the Netherlands...
January 6, 2017: Age and Ageing
https://www.readbyqxmd.com/read/28063606/-assessment-of-antibiotic-use-and-impact-of-an-intervention-intended-to-modify-the-prescribing-behavior-in-surgical-prophylaxis-in-6hospitals-in-the-metropolitan-area-of-monterrey-mexico
#3
Gerardo Del Carmen Palacios-Saucedo, Mauricio de la Garza-Camargo, Evangelina Briones-Lara, Sandra Carmona-González, Ricardo García-Cabello, Luis Arturo Islas-Esparza, Gustavo Saldaña-Flores, Juan Roberto González-Cano, Román González-Ruvalcaba, Francisco Javier Valadez-Botello, Gerardo Enrique Muñoz-Maldonado, Carlos Alberto Montero-Cantú, Rita Delia Díaz-Ramos, Fortino Solórzano-Santos
BACKGROUND: Improper use of antibiotics increases antimicrobial resistance. OBJECTIVE: Evaluate the use of antibiotics and the impact of an intervention designed to improve antibiotic prescription for surgical prophylaxis in 6 hospitals of Monterrey, Mexico. MATERIAL AND METHODS: Design: A prospective multicenter survey and a pretest-postest experimental study. Phase 1: Survey to evaluate the use of antibiotics through an especially designed guide...
January 4, 2017: Cirugia y Cirujanos
https://www.readbyqxmd.com/read/28057949/impact-of-targeted-educational-interventions-on-clostridium-difficile-infection-treatment-in-critically-ill-adults
#4
Drayton A Hammond, Catherine A Hughes, Jacob T Painter, Rose E Pennick, Kshitij Chatterjee, Bradley Boye, Nikhil Meena
Background: Clostridium difficile infection (CDI) is a growing clinical and economic burden throughout the world. Pharmacists often are members of the primary care team in the intensive care unit (ICU) setting; however, the impact of pharmacists educating other health care providers on appropriateness of CDI treatment has not been previously examined. Objective: This study was performed to determine the impact of structured educational interventions on CDI treatment on appropriateness of CDI treatment and clinical outcomes...
December 2016: Hospital Pharmacy
https://www.readbyqxmd.com/read/28056068/the-association-between-polypharmacy-and-dementia-a-nested-case-control-study-based-on-a-12-year-longitudinal-cohort-database-in-south-korea
#5
Hae-Young Park, Ji-Won Park, Hong Ji Song, Hyun Soon Sohn, Jin-Won Kwon
Dementia is a major concern among growing chronic diseases in the aging society and its association with polypharmacy has not been adequately assessed. The objective of this study was to determine the association between polypharmacy and dementia through multiple statistical approaches. We conducted a nested case-control study for newly diagnosed dementia cases using the South Korean National Health Insurance Service sample cohort database (2002-2013, n = 1,025,340). Interactions between polypharmacy (an average use of ≥5 prescription drugs daily) and comorbidities or potentially inappropriate medications (PIMs) were tested...
2017: PloS One
https://www.readbyqxmd.com/read/28053591/potentially-inappropriate-medications-prescribed-for-elderly-patients-through-family-physicians
#6
Abdulaziz Al Odhayani, Ayla Tourkmani, Mohammed Alshehri, Hala Alqahtani, Adel Mishriky
The elderly population is increasing throughout the globe, resulting in higher healthcare costs. Potential inappropriate medication (PIM) prescriptions are a major health problem affecting the elderly persons. Due to limited studies in PIM use in primary care and home healthcare in Saudi Arabia, we aim to examine the extent of PIM prescription for and use by elderly patients. This study was carried out with 798 elderly patients, arbitrarily selected from Prince Sultan Medical Military City through the patient register...
January 2017: Saudi Journal of Biological Sciences
https://www.readbyqxmd.com/read/28050623/clinical-relevance-of-the-stopp-start-criteria-in-hip-fracture-patients
#7
Johan Lönnbro, Susanna M Wallerstedt
PURPOSE: The aim of this study was to investigate the clinical relevance of potentially inappropriate medications (PIMs), identified by the STOPP criteria, and potential prescribing omissions (PPOs), identified by the START criteria, and to identify predictors for clinically relevant PIMs and PPOs. METHODS: The STOPP and START criteria were applied on the medication lists of 200 older hip fracture patients, consecutively recruited to a randomized controlled study in 2009...
January 3, 2017: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28049239/from-visiting-a-physician-to-expecting-antibiotics-korean-perspectives-and-practices-toward-respiratory-tract-infections
#8
Leila Freidoony, Chun Bae Kim, Hamid Haghani, Myung Bae Park, Sei Jin Chang, Sang Ha Kim, Sang Baek Koh
Antibiotic resistance is steadily rising worldwide. Respiratory tract infections (RTIs) are common indications, mostly imprudent, for antibiotic prescriptions in outpatient setting. In Korea, antibiotic prescription rate for RTIs is still high. As physician visit and antibiotic prescribing are influenced by patient's perceptions and beliefs, we aimed to explore the general public's perspectives and practices toward RTIs and to develop the 'RTI clinical iceberg.' A cross-sectional survey was conducted in Wonju Severance Christian Hospital (WSCH) among 550 adults attending outpatient departments during January 2016...
February 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28048788/mo-fg-207a-03-radiation-and-cancer-perspectives-from-the-trenches-are-we-providing-care-or-promoting-scare
#9
D Frush
: There has been increasing use of CT scans globally. This increased use is not in itself of concern, and largely reflects the remarkable clinical benefits of CT. Inappropriate use of CT is, however, of concern, particularly as the potential for carcinogenic effects is yet to be fully understood. The first major media attention to cancer risk from CT scan arose from a series of papers and an Editorial published in AJR in 2001. This was followed by another series of papers in 2007 and associated media attention to the estimation of the number of cancer deaths that may occur in US as a result of radiation exposure from CT...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048056/mo-fg-207a-00-radiation-and-cancer-reality-extrapolations-myths-practice
#10
Madan Rehani, Donald Miller
: There has been increasing use of CT scans globally. This increased use is not in itself of concern, and largely reflects the remarkable clinical benefits of CT. Inappropriate use of CT is, however, of concern, particularly as the potential for carcinogenic effects is yet to be fully understood. The first major media attention to cancer risk from CT scan arose from a series of papers and an Editorial published in AJR in 2001. This was followed by another series of papers in 2007 and associated media attention to the estimation of the number of cancer deaths that may occur in US as a result of radiation exposure from CT...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047397/mo-fg-207a-01-overview-of-global-usage-of-x-rays-for-diagnostic-purpose-issues-and-approaches-for-safety
#11
M Rehani
: There has been increasing use of CT scans globally. This increased use is not in itself of concern, and largely reflects the remarkable clinical benefits of CT. Inappropriate use of CT is, however, of concern, particularly as the potential for carcinogenic effects is yet to be fully understood. The first major media attention to cancer risk from CT scan arose from a series of papers and an Editorial published in AJR in 2001. This was followed by another series of papers in 2007 and associated media attention to the estimation of the number of cancer deaths that may occur in US as a result of radiation exposure from CT...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046733/mo-fg-207a-02-what-do-we-really-know-about-cancer-risks-at-doses-pertinent-to-ct-scans
#12
D Brenner
: There has been increasing use of CT scans globally. This increased use is not in itself of concern, and largely reflects the remarkable clinical benefits of CT. Inappropriate use of CT is, however, of concern, particularly as the potential for carcinogenic effects is yet to be fully understood. The first major media attention to cancer risk from CT scan arose from a series of papers and an Editorial published in AJR in 2001. This was followed by another series of papers in 2007 and associated media attention to the estimation of the number of cancer deaths that may occur in US as a result of radiation exposure from CT...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28045648/-inappropriate-prescribing-in-older-people-time-to-take-action
#13
Alfonso J Cruz-Jentoft
No abstract text is available yet for this article.
January 1, 2017: Farmacia Hospitalaria
https://www.readbyqxmd.com/read/28042352/potentially-inappropriate-prescribing-andthe-risk-of-adverse-drug-reactions-in-critically-ill-older-adults
#14
Thamires B Galli, Wálleri C Reis, Vânia M Andrzejevski
BACKGROUND: Potentially inappropriate medication (PIM) use in the elderly is associated with increased risk of adverse drug reactions (ADRs), but there is limited information regarding PIM use in the intensive care unit (ICU) setting. OBJECTIVE: The aim of the study is to describe the prevalence and factors associated with the use of PIM and the occurrence of PIM-related adverse reactions in the critically ill elderly. METHODS: This study enrolled all critically ill older adults (60 years or more) admitted to medical or cardiovascular ICUs between January and December 2013, in a large tertiary teaching hospital...
October 2016: Pharmacy Practice
https://www.readbyqxmd.com/read/28039932/potentially-inappropriate-medications-in-elderly-japanese-patients-effects-of-pharmacists-assessment-and-intervention-based-on-screening-tool-of-older-persons-potentially-inappropriate-prescriptions-criteria-ver-2
#15
T Kimura, F Ogura, K Yamamoto, A Uda, T Nishioka, M Kume, H Makimoto, I Yano, M Hirai
WHAT IS KNOWN AND OBJECTIVES: The Screening Tool of Older Persons' Potentially Inappropriate Prescriptions (stopp) criteria were updated in 2014 (stopp criteria ver.2), but few studies have evaluated the usefulness of stopp criteria in elderly patients. This prospective observational study evaluated the prevalence of potentially inappropriate medications (PIMs), and the efficacy of hospital pharmacists' assessment and intervention based on stopp criteria ver.2. METHODS: The study was conducted at three medical units of Kobe University Hospital between April 2015 and March 2016...
December 31, 2016: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/28029487/a-review-of-newly-approved-antibiotics-and-antibiotics-reserved-for-resistant-infections-implications-for-emergency-medicine
#16
REVIEW
Maryann Mazer-Amirshahi, Ali Pourmand, Larissa May
Millions of patients are evaluated every year in the emergency department (ED) for bacterial infections. Emergency physicians often diagnose and prescribe initial antibiotic therapy for a variety of bacterial infections, ranging from simple urinary tract infections to severe sepsis. In life-threatening infections, inappropriate choice of initial antibiotic has been shown to increase morbidity and mortality. As such, initiation of appropriate antibiotic therapy on the part of the emergency physician is critical...
October 17, 2016: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28025925/contemporary-trends-in-oral-antiplatelet-agent-use-in-patients-treated-with-percutaneous-coronary-intervention-for-acute-coronary-syndrome
#17
Kibum Kim, Todd A Lee, Daniel R Touchette, Robert J DiDomenico, Amer K Ardati, Surrey M Walton
BACKGROUND: Recent trials demonstrated the efficacy of prasugrel and ticagrelor compared with clopidogrel in the reduction of cardiovascular complications in patients with acute coronary syndrome (ACS). However, it is unclear how use of the 3 antiplatelet medications has changed in commercially insured patients since the advent of the new agents. OBJECTIVES: To (a) describe the adoption of prasugrel and ticagrelor in patients who received percutaneous coronary intervention (PCI) for the onset of ACS and (b) explore patient factors associated with the selection of the drug to provide insight into utilization patterns of these antiplatelet agents...
January 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28024315/patient-physician-and-health-system-factors-influencing-the-quality-of-antidepressant-and-sedative-prescribing-for-older-community-dwelling-adults
#18
Rian Marie Extavour, Matthew Perri
OBJECTIVE: To identify determinants of potentially inappropriate (PI) antidepressant and anxiolytic/sedative prescribing for older, community-dwelling adults. DATA SOURCES/STUDY SETTING: Office visits from the 2010 National Ambulatory Medical Care Survey. STUDY DESIGN: A cross-sectional study measuring associations between various patient and physician factors and prescribing of PI antidepressants, and PI sedatives among elderly, using Beers 2012/2015 criteria, a clinical decision model, and multivariate logistic regressions...
December 26, 2016: Health Services Research
https://www.readbyqxmd.com/read/28009450/multi-compartment-compliance-aids-in-the-community-the-prevalence-of-potentially-inappropriate-medications
#19
David Counter, Derek Stewart, Joan MacLeod, James S Mclay
AIMS: To assess the prevalence of potentially inappropriate medications (PIM) use in a population of community-based multi-compartment compliance aid (MCA) users in North- Scotland. METHODS: Data for MCAs dispensed by 48 of the 50 community pharmacies in Aberdeen City between 1(st) June to 31(st) October 2014, together with concurrently prescribed medications, patient demographics and Carstairs Index of social deprivation were recorded. Drug-specific quality indicators for PIMs from the Swedish National Board of Health and Welfare were applied and bivariate logistic regression analysis used to assess for associations with demographic variables...
December 23, 2016: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28008599/screening-tool-of-older-person-s-prescriptions-screening-tools-to-alert-doctors-to-right-treatment-medication-criteria-modified-for-u-s-nursing-home-setting
#20
Dmitry Khodyakov, Aileen Ochoa, Brianne L Olivieri-Mui, Carla Bouwmeester, Barbara J Zarowitz, Meenakshi Patel, Diana Ching, Becky Briesacher
OBJECTIVES: To develop a set of prescribing indicators measurable with available data from electronic nursing home (NH) databases by adapting the European-based 2014 Screening Tool of Older Person's Prescriptions (STOPP) and Screening Tools to Alert Doctors to Right Treatment (START) criteria of potentially inappropriate and underused medications for the U.S. SETTING: HASH(0x3fb2f90) DESIGN: A two-stage expert panel process. In the first stage, the investigator team reviewed 114 criteria for compatibility and measurability...
December 23, 2016: Journal of the American Geriatrics Society
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