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https://www.readbyqxmd.com/read/27913962/bathing-and-associated-treatments-in-atopic-dermatitis
#1
REVIEW
Julia K Gittler, Jason F Wang, Seth J Orlow
Atopic dermatitis is one of the most common complaints presenting to dermatologists, and patients typically inquire as to appropriate bathing recommendations. Although many dermatologists, allergists, and primary-care practitioners provide explicit bathing instructions, recommendations regarding frequency of bathing, duration of bathing, and timing related to emollient and medication application relative to bathing vary widely. Conflicting and vague guidelines stem from knowledge related to the disparate effects of water on skin, as well as a dearth of studies, especially randomized controlled trials, evaluating the effects of water and bathing on the skin of patients with atopic dermatitis...
December 3, 2016: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/27913817/the-contribution-of-response-conflict-multisensory-integration-and-body-mediated-attention-to-the-crossmodal-congruency-effect
#2
Francesco Marini, Daniele Romano, Angelo Maravita
The crossmodal congruency task is a consolidated paradigm for investigating interactions between vision and touch. In this task, participants judge the elevation of a tactile target stimulus while ignoring a visual distracter stimulus that may occur at a congruent or incongruent elevation, thus engendering a measure of visuo-tactile interference (crossmodal congruency effect, CCE). The CCE reflects perceptual, attentional, and response-related factors, but their respective roles and interactions have not been set out yet...
December 2, 2016: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/27913453/movement-patterns-of-cheetahs-acinonyx-jubatus-in-farmlands-in-botswana
#3
L K Van der Weyde, T Y Hubel, J Horgan, J Shotton, R McKenna, A M Wilson
Botswana has the second highest population of cheetah (Acinonyx jubatus) with most living outside protected areas. As a result, many cheetahs are found in farming areas, bringing them into conflict with people. This study aimed to look at movement patterns of cheetahs in farming environments to determine whether cheetahs have adapted their movements in these human-dominated landscapes. We fitted high-time resolution GPS collars to cheetahs in the Ghanzi farmlands of Botswana. GPS locations were used to calculate home range sizes as well as number and duration of visits to landscape features using a time-based local convex hull method...
December 2, 2016: Biology Open
https://www.readbyqxmd.com/read/27913451/treating-primary-dysmenorrhoea-with-acupuncture-a-narrative-review-of-the-relationship-between-acupuncture-dose-and-menstrual-pain-outcomes
#4
Mike Armour, Caroline A Smith
OBJECTIVE: A number of randomised controlled trials have been performed to determine the effectiveness or efficacy of acupuncture in primary dysmenorrhoea. The objective of this review was to explore the relationship between the 'dose' of the acupuncture intervention and menstrual pain outcomes. METHODS: Eight databases were systematically searched for trials examining penetrating body acupuncture for primary dysmenorrhoea published in English up to September 2015...
December 2016: Acupuncture in Medicine: Journal of the British Medical Acupuncture Society
https://www.readbyqxmd.com/read/27912938/complementary-and-alternative-medicine-for-lowering-blood-lipid-levels-a-systematic-review-of-systematic-reviews
#5
REVIEW
Paul Posadzki, Abdullah M N AlBedah, Mohamed M K Khalil, Meshari S AlQaed
BACKGROUND: The aim of this article is to summarize and critically evaluate the evidence from systematic reviews (SRs) of complementary and alternative medicine (CAM) for lowering blood lipid levels (BLL). METHODS: Eight electronic databases were searched until March 2016. Additionally, all the retrieved references were inspected manually for further relevant papers. Systematic reviews were considered eligible, if they included patients of any age and/or gender with elevated blood lipid levels using any type of CAM...
December 2016: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/27912056/conflict-resolution-in-the-genome-how-transcription-and-replication-make-it-work
#6
REVIEW
Stephan Hamperl, Karlene A Cimprich
The complex machineries involved in replication and transcription translocate along the same DNA template, often in opposing directions and at different rates. These processes routinely interfere with each other in prokaryotes, and mounting evidence now suggests that RNA polymerase complexes also encounter replication forks in higher eukaryotes. Indeed, cells rely on numerous mechanisms to avoid, tolerate, and resolve such transcription-replication conflicts, and the absence of these mechanisms can lead to catastrophic effects on genome stability and cell viability...
December 1, 2016: Cell
https://www.readbyqxmd.com/read/27911842/map-reading-navigating-from-maps-and-the-medial-temporal-lobe
#7
Zhisen J Urgolites, Soyun Kim, Ramona O Hopkins, Larry R Squire
We administered map-reading tasks in which participants navigated an array of marks on the floor by following paths on hand-held maps that made up to nine turns. The burden on memory was minimal because the map was always available. Nevertheless, because the map was held in a fixed position in relation to the body, spatial computations were continually needed to transform map coordinates into geographical coordinates as participants followed the maps. Patients with lesions limited to the hippocampus (n = 5) performed similar to controls at all path lengths (experiment 1)...
November 28, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27911752/frontosubthalamic-circuits-for-control-of-action-and-cognition
#8
Adam R Aron, Damian M Herz, Peter Brown, Birte U Forstmann, Kareem Zaghloul
The subthalamic nucleus (STN) of the basal ganglia appears to have a potent role in action and cognition. Anatomical and imaging studies show that different frontal cortical areas directly project to the STN via so-called hyperdirect pathways. This review reports some of the latest findings about such circuits, including simultaneous recordings from cortex and the STN in humans, single-unit recordings in humans, high-resolution fMRI, and neurocomputational modeling. We argue that a major function of the STN is to broadly pause behavior and cognition when stop signals, conflict signals, or surprise signals occur, and that the fronto-STN circuits for doing this, at least for stopping and conflict, are dissociable anatomically and in terms of their spectral reactivity...
November 9, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27911566/pedometer-step-count-targets-during-pulmonary-rehabilitation-in-copd-a-randomized-controlled-trial
#9
Claire M Nolan, Matthew Maddocks, Jane L Canavan, Sarah E Jones, Veronica Delogu, Djeya Kaliaraju, Winston Banya, Samantha S C Kon, Michael I Polkey, William D-C Man
RATIONALE: Increasing physical activity is a key therapeutic aim in COPD. Pulmonary rehabilitation (PR) improves exercise capacity, but there is conflicting evidence regarding its ability to improve physical activity levels. OBJECTIVE: To determine whether using pedometers as an adjunct to PR can enhance time spent in at least moderate intensity physical activity (time ≥ 3METs) in people with COPD. METHODS: In this single-blinded randomized controlled trial, participants were assigned 1:1 to receive control (PR comprising 8 weeks, two supervised sessions/week) or intervention (PR plus pedometer-directed step targets, reviewed weekly for 8 weeks)...
December 2, 2016: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/27911489/palliative-care-interventions-in-advanced-dementia
#10
REVIEW
Edel Murphy, Katherine Froggatt, Sheelah Connolly, Eamon O'Shea, Elizabeth L Sampson, Dympna Casey, Declan Devane
BACKGROUND: Dementia is a chronic, progressive and ultimately fatal neurodegenerative disease. Advanced dementia is characterised by profound cognitive impairment, inability to communicate verbally and complete functional dependence. Usual care of people with advanced dementia is not underpinned universally by a palliative approach. Palliative care has focused traditionally on care of people with cancer but for more than a decade, there have been increased calls worldwide to extend palliative care services to include all people with life-limiting illnesses in need of specialist care, including people with dementia...
December 2, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27911486/extended-mortality-results-for-prostate-cancer-screening-in-the-plco-trial-with-median-follow-up-of-15-years
#11
Paul F Pinsky, Philip C Prorok, Kelly Yu, Barnett S Kramer, Amanda Black, John K Gohagan, E David Crawford, Robert L Grubb, Gerald L Andriole
BACKGROUND: Two large-scale prostate cancer screening trials using prostate-specific antigen (PSA) have given conflicting results in terms of the efficacy of such screening. One of those trials, the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial, previously reported outcomes with 13 years of follow-up. This study presents updated findings from the PLCO trial. METHODS: The PLCO trial randomized subjects from 1993 to 2001 to an intervention or control arm...
December 1, 2016: Cancer
https://www.readbyqxmd.com/read/27911416/the-indirect-neuron-astrocyte-coculture-assay-an-in-vitro-set-up-for-the-detailed-investigation-of-neuron-glia-interactions
#12
Christine Gottschling, Egor Dzyubenko, Maren Geissler, Andreas Faissner
Proper neuronal development and function is the prerequisite of the developing and the adult brain. However, the mechanisms underlying the highly controlled formation and maintenance of complex neuronal networks are not completely understood thus far. The open questions concerning neurons in health and disease are diverse and reaching from understanding the basic development to investigating human related pathologies, e.g., Alzheimer's disease and Schizophrenia. The most detailed analysis of neurons can be performed in vitro...
November 14, 2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/27911239/microvascular-decompression-of-the-cochleovestibular-nerve-for-treatment-of-tinnitus-and-vertigo-a-systematic-review-and-meta-analysis-of-individual-patient-data
#13
Minke J C van den Berge, J Marc C van Dijk, Iris A Posthumus, Nynke Smidt, Pim van Dijk, Rolien H Free
OBJECTIVE Microvascular decompression (MVD) is regarded as a valid treatment modality in neurovascular conflicts (NVCs) causing, for example, trigeminal neuralgia and hemifacial spasms. An NVC of the cochleovestibular nerve might cause tinnitus and/or vertigo; however, general acceptance of MVD for this indication is lacking. The aim of this study was to investigate the effectiveness, safety, and prognostic factors for success of MVD of the cochleovestibular nerve. METHODS A systematic review and meta-analysis of individual patient data (IPD) were conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses and Individual Patient Data (PRISMA-IPD) guidelines...
December 2, 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27911096/evaluating-health-advice-in-a-web-2-0-environment-the-impact-of-multiple-user-generated-factors-on-hiv-advice-perceptions
#14
Joseph B Walther, Jeong-Woo Jang, Ashley A Hanna Edwards
Unlike traditional media, social media systems often present information of different types from different kinds of contributors within a single message pane, a juxtaposition of potential influences that challenges traditional health communication processing. One type of social media system, question-and-answer advice systems, provides peers' answers to health-related questions, which yet other peers read and rate. Responses may appear good or bad, responders may claim expertise, and others' aggregated evaluations of an answer's usefulness may affect readers' judgments...
December 2, 2016: Health Communication
https://www.readbyqxmd.com/read/27910865/auditory-evoked-potential-could-reflect-emotional-sensitivity-and-impulsivity
#15
Ji Sun Kim, Sungkean Kim, Wookyoung Jung, Chang-Hwan Im, Seung-Hwan Lee
Emotional sensitivity and impulsivity could cause interpersonal conflicts and neuropsychiatric problems. Serotonin is correlated with behavioral inhibition and impulsivity. This study evaluated whether the loudness dependence of auditory evoked potential (LDAEP), a potential biological marker of central serotonergic activity, could reflect emotional sensitivity and impulsivity. A total of 157 healthy individuals were recruited, who performed LDAEP and Go/Nogo paradigms during electroencephalogram measurement...
December 2, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27910797/staging-practice-for-prostate-cancer-varies-and-is-not-in-line-with-clinical-guidelines
#16
Lars J Petersen, Yuliya Shuytsky, Helle D Zacho
INTRODUCTION: The objective was to describe regional variations in M-staging in patients with newly diagnosed prostate cancer within a Danish county and to compare clinical practice with guideline recommendations. METHODS: Data were as captured from 1) a prospective, non-interventional study counting 635 consecutive patients referred for M-staging in the 2008-2009 period at three regional hospitals within one county, and 2) a questionnaire on M-staging practice completed by the five sites performing M-staging in the same county in 2015...
December 2016: Danish Medical Journal
https://www.readbyqxmd.com/read/27910738/cartilage-repair-in-the-degenerative-ageing-knee
#17
Mats Brittberg, Andreas H Gomoll, José A Canseco, Jack Far, Martin Lind, James Hui
Background and purpose - Cartilage damage can develop due to trauma, resulting in focal chondral or osteochondral defects, or as more diffuse loss of cartilage in a generalized organ disease such as osteoarthritis. A loss of cartilage function and quality is also seen with increasing age. There is a spectrum of diseases ranging from focal cartilage defects with healthy surrounding cartilage to focal lesions in degenerative cartilage, to multiple and diffuse lesions in osteoarthritic cartilage. At the recent Aarhus Regenerative Orthopaedics Symposium (AROS) 2015, regenerative challenges in an ageing population were discussed by clinicians and basic scientists...
December 2, 2016: Acta Orthopaedica
https://www.readbyqxmd.com/read/27910657/time-dependent-analysis-of-visible-helium-line-ratios-for-electron-temperature-and-density-diagnostic-using-synthetic-simulations-on-nstx-u
#18
J M Muñoz Burgos, T Barbui, O Schmitz, D Stutman, K Tritz
Helium line-ratios for electron temperature (Te) and density (ne) plasma diagnostic in the Scrape-Off-Layer (SOL) and edge regions of tokamaks are widely used. Due to their intensities and proximity of wavelengths, the singlet, 667.8 and 728.1 nm, and triplet, 706.5 nm, visible lines have been typically preferred. Time-dependency of the triplet line (706.5 nm) has been previously analyzed in detail by including transient effects on line-ratios during gas-puff diagnostic applications. In this work, several line-ratio combinations within each of the two spin systems are analyzed with the purpose of eliminating transient effects to extend the application of this powerful diagnostic to high temporal resolution characterization of plasmas...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27910610/non-magnetic-flexible-heaters-for-spin-exchange-optical-pumping-of-3-he-and-other-applications
#19
T Ino, H Hayashida, H Kira, T Oku, K Sakai
Spin polarized (3)He gas is currently widely used in various scientific fields and in medical diagnosis applications. The spin polarization of (3)He nuclei can be achieved by spin-exchange optical pumping (SEOP). In SEOP, the (3)He gas is enclosed in a glass cell together with alkali metals and is then heated to maintain the alkali metal vapor pressures at the appropriate levels. However, polarized (3)He gas is highly sensitive to any inhomogeneity in its magnetic field, and any small field gradients caused by the heaters may cause degradation of the (3)He polarization...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27910162/effects-of-sample-size-and-distributional-assumptions-on-competing-models-of-the-factor-structure-of-the-panss-and-bprs
#20
Stephen J Tueller, Kiersten L Johnson, Kevin J Grimm, Sarah L Desmarais, Brian G Sellers, Richard A Van Dorn
Factor analytic work on the Positive and Negative Syndrome Scale (PANSS) and Brief Psychiatric Rating Scale (BPRS) has yielded varied and conflicting results. The current study explored potential causes of these discrepancies. Prior research has been limited by small sample sizes and an incorrect assumption that the items are normally distributed when in practice responses are highly skewed ordinal variables. Using simulation methodology, we examined the effects of sample size, (in)correctly specifying item distributions, collapsing rarely endorsed response categories, and four factor analytic models...
December 2, 2016: International Journal of Methods in Psychiatric Research
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