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Papillary serous carcinoma

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https://www.readbyqxmd.com/read/28631655/erratum-squash-cytodiagnosis-of-synchronous-papillary-serous-carcinoma-of-ovary-and-endometrium-with-demonstration-of-serous-tubal-intraepithelial-carcinoma-as-a-precursor-lesion
#1
(no author information available yet)
[This corrects the article DOI: 10.4103/0377-4929.200039].
April 2017: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/28571149/vegf-expression-to-support-targeted-therapy-in-ovarian-surface-epithelial-neoplasms
#2
Sudeshna Mukherjee, Mallika Pal, Susmita Mukhopadhyay, Indranil Das, Rathin Hazra, Suman Ghosh, Rajib Kumar Mondal, Runa Bal
INTRODUCTION: Vascular Endothelial Growth Factor (VEGF), a promoter of angiogenesis, is a promising target for anti-angiogenic therapy in ovarian cancer. In our study, we examined the expression of VEGF in the spectrum of epithelial ovarian neoplasms (benign, borderline and malignant) by Immunohistochemistry (IHC). AIM: Diagnosing ovarian epithelial neoplasms, examining the expression of VEGF in benign, borderline and malignant neoplasms and correlating it with histological grade and stage of malignant cases...
April 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28551646/primary-peritoneal-serous-carcinoma-in-men-a-rare-and-non-brca-associated-entity
#3
Susan L Neuhausen, Hagit Shani, Lital Keinan Boker, Linda Steele, Barbara G Silverman, Laura Ottini, Valentina Silvestri, Yael Laitman, Jacob Korach, Tamar Perri, Eitan Friedman
BACKGROUND: Primary peritoneal serous carcinoma (PPSC) is a rare neoplasm. The paucity of reported cases among men may provide insight to the cell of origin of PPSC. MATERIALS AND METHODS: A search for the ICD 0-3 code of PPSC (C48.2) in the following datasets: the Israeli National Cancer registry (INCR), the Surveillance, Epidemiology, and End Results (SEER) database in the USA, Israeli male BRCA carriers, male high-risk and BRCA carriers in a USA study, and the Italian Study on Male Breast Cancer (MBC) were performed...
June 2017: Anticancer Research
https://www.readbyqxmd.com/read/28522787/surgical-treatment-of-pancreatic-cystic-tumors
#4
Beata Jabłońska, Łukasz Braszczok, Weronika Szczęsny-Karczewska, Beata Dubiel-Braszczok, Paweł Lampe
The aim of this study was to assess short-term outcomes of surgical treatment of pancreatic cystic tumors (PCTs). MATERIAL AND METHODS: We retrospectively reviewed medical records of 46 patients (31 women and 15 men) who had undergone surgery for pancreatic cystic tumors in our department. RESULTS: Pancreatic cystic tumors were located within the pancreatic head (21), body (11), tail (13), and whole pancreas (1). The following surgical procedures were performed: pancreatoduodenectomy (20), central pancreatectomy (9), distal pancreatectomy (3), distal pancreatectomy with splenectomy (3), distal extended pancreatectomy with splenectomy (2), total pancreatectomy (1), duodenum preserving pancreatic head resection (1), local tumor resection (4), and other procedures (2)...
February 28, 2017: Polski Przeglad Chirurgiczny
https://www.readbyqxmd.com/read/28488545/determination-of-braf-v600e-ve1-protein-expression-and-braf-gene-mutation-status-in-codon-600-in-borderline-and-low-grade-ovarian-cancers
#5
Pawel Sadlecki, Pawel Walentowicz, Magdalena Bodnar, Andrzej Marszalek, Marek Grabiec, Malgorzata Walentowicz-Sadlecka
Epithelial ovarian tumors are a group of morphologically and genetically heterogeneous neoplasms. Based on differences in clinical phenotype and genetic background, ovarian neoplasms are classified as low-grade and high-grade tumor. Borderline ovarian tumors represent approximately 10%-20% of all epithelial ovarian masses. Various histological subtypes of ovarian malignancies differ in terms of their risk factor profiles, precursor lesions, clinical course, patterns of spread, molecular genetics, response to conventional chemotherapy, and prognosis...
May 2017: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/28469317/impact-of-surepath-%C3%A2-liquid-based-preparation-in-cytological-analysis-of-peritoneal-washing-in-practice-of-gynecologic-oncology
#6
Ruchita Tyagi, Nalini Gupta, Priyanka Bhagat, Shalini Gainder, Bhavna Rai, L K Dhaliwal, Arvind Rajwanshi
CONTEXT: Peritoneal washing is performed for staging of gynecologic tumors to detect subclinical intraperitoneal metastases. AIM: The aim of the present study was to assess the impact of SurePath™ liquid-based cytology (LBC) in peritoneal washing in various gynecological malignancies. SETTINGS AND DESIGN: An audit of peritoneal-fluid/washing (January 2012 to July 2013) was performed with corresponding gynecologic specimens. All peritoneal washings were processed using both conventional and LBC technique...
April 2017: Journal of Cytology
https://www.readbyqxmd.com/read/28463669/pancreatic-cystic-lesions-diagnostic-management-and-indications-for-operation-part-i
#7
Ferdinand Bauer
We notice an increasing frequency in the detection and evaluation of pancreatic cystic lesions (PCLs) over the last three decades. They show awide spectrum of imaging and clinical features. The diagnosis and discrimination of these lesions are very important because of the risk for concurrent or later development of malignancy. The main reason is the increased awareness of these lesions and the extensive use of cross-sectional imaging, an always improving technique (1). Commonly, PCLs are diagnosed incidentally during investigation for often unrelated and nonspecific abdominal complaints using state-of-the art abdominal imaging (CT, MRT)...
March 2017: Chirurgia
https://www.readbyqxmd.com/read/28416487/metabolic-markers-and-statistical-prediction-of-serous-ovarian-cancer-aggressiveness-by-ambient-ionization-mass-spectrometry-imaging
#8
Marta Sans, Kshipra Gharpure, Robert Tibshirani, Jialing Zhang, Li Liang, Jinsong Liu, Jonathan H Young, Robert L Dood, Anil K Sood, Livia S Eberlin
Ovarian high-grade serous carcinoma (HGSC) results in the highest mortality among gynecological cancers, developing rapidly and aggressively. Dissimilarly, serous borderline ovarian tumors (BOT) can progress into low-grade serous carcinomas and have relatively indolent clinical behavior. The underlying biological differences between HGSC and BOT call for accurate diagnostic methodologies and tailored treatment options, and identification of molecular markers of aggressiveness could provide valuable biochemical insights and improve disease management...
April 17, 2017: Cancer Research
https://www.readbyqxmd.com/read/28399919/long-term-survival-of-high-grade-primary-peritoneal-papillary-serous-adenocarcinoma-a-case-report-and-literature-review
#9
Jingping Yuan, Liang He, Bing Han, Yan Li
BACKGROUND: Primary peritoneal papillary serous carcinoma (PPPSC) is an uncommon disease which has a high malignancy and a poor prognosis. CASE PRESENTATION: We report here a long-term survival case of PPPSC with postoperative lung metastasis. A 62-year-old female patient with PPPSC was administered two cycles of neoadjuvant chemotherapy (NAC) followed by cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) and six cycles of platinum-based (docetaxel + carboplatin) intraperitoneal chemotherapy postoperatively...
April 11, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28398226/melatonin-reduces-angiogenesis-in-serous-papillary-ovarian-carcinoma-of-ethanol-preferring-rats
#10
Yohan Ricci Zonta, Marcelo Martinez, Isabel Cristina C Camargo, Raquel F Domeniconi, Luiz Antonio Lupi Júnior, Patricia Fernanda F Pinheiro, Russel J Reiter, Francisco Eduardo Martinez, Luiz Gustavo A Chuffa
Angiogenesis is a hallmark of ovarian cancer (OC); the ingrowth of blood vessels promotes rapid cell growth and the associated metastasis. Melatonin is a well-characterized indoleamine that possesses important anti-angiogenic properties in a set of aggressive solid tumors. Herein, we evaluated the role of melatonin therapy on the angiogenic signaling pathway in OC of an ethanol-preferring rat model that mimics the same pathophysiological conditions occurring in women. OC was chemically induced with a single injection of 7,12-dimethylbenz(a)anthracene (DMBA) under the ovarian bursa...
April 11, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28394551/mesonephric-adenocarcinoma-of-endocervix-with-lobular-mesonephric-hyperplasia-case-report
#11
Mario Puljiz, Damir Danolić, Lucija Kostić, Ilija Alvir, Darko Tomica, Ivica Mamić, Ivana Vlastelica Munivrana, Marko Puljiz, Danko Velimir Vrdoljak, Melita Perić Balja
Mesonephric adenocarcinoma is a rare variant of cervical adenocarcinoma. We present a case of mesonephric adenocarcinoma of endocervix with cervical and vaginal lobular mesonephric hyperplasia in a 57-year-old woman. Vaginal bleeding persisting for 12 months was the only symptom. Histopathologic findings and characteristic immunophenotype are crucial for the diagnosis. The tumor was composed of papillary formation with a central fi brovascular stroma, villoglandular and densely compact tubular structures containing intraluminal eosinophilic secretion, and coated with one or more rows of cylindrical atypical epithelial cells...
June 2016: Acta Clinica Croatica
https://www.readbyqxmd.com/read/28375927/impact-of-chemotherapy-and-radiotherapy-on-management-of-early-stage-clear-cell-and-papillary-serous-carcinoma-of-the-uterus
#12
Julian C Hong, Jonathan Foote, Gloria Broadwater, Stéphanie Gaillard, Laura J Havrilesky, Junzo P Chino
OBJECTIVE: The aim of the study was to assess interaction of lymph node dissection (LND), adjuvant chemotherapy (CT), and radiotherapy (RT) in stage I uterine papillary serous carcinoma (UPSC) and uterine clear cell carcinoma (UCC). METHODS/MATERIALS: The National Cancer Data Base was queried for women diagnosed with International Federation of Gynecology and Obstetrics stage I UPSC and UCC from 1998 to 2012. Overall survival (OS) was estimated for combinations of RT and CT by the Kaplan-Meier method stratified by histology and LND...
May 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28343693/utility-of-radiation-therapy-for-early-stage-uterine-papillary-serous-carcinoma
#13
Stephanie Cham, Yongmei Huang, Ana I Tergas, June Y Hou, William M Burke, Israel Deutsch, Cande V Ananth, Alfred I Neugut, Dawn L Hershman, Jason D Wright
OBJECTIVE: Early-stage uterine papillary serous carcinoma (UPSC) has a poor prognosis and high recurrence rate. While adjuvant chemotherapy is generally recommended, the role of radiation is uncertain. We examined the association between vaginal brachytherapy and whole pelvic radiation and survival in women treated with and without adjuvant chemotherapy. METHODS: The National Cancer Data Base was used to identify women with stage I-II UPSC treated between 1998 and 2012...
May 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28331341/investigating-the-expression-effect-and-tumorigenic-pathway-of-padi2-in-tumors
#14
Wei Guo, Yabing Zheng, Bing Xu, Fang Ma, Chang Li, Xiaoqian Zhang, Yao Wang, Xiaotian Chang
BACKGROUND: Peptidylarginine deiminase (PAD) catalyzes the conversion of arginine residues to citrulline residues, termed citrullination. Recent studies have suggested that PAD isoform 2 (PADI2) plays an important role in tumors, although its tumorigenic effect and mechanism are largely unknown. MATERIALS AND METHODS: Immunohistochemistry and enzyme-linked immunosorbent assay (ELISA) were used to investigate the expression level of PADI2 in various tumor tissues and patient blood samples, respectively...
2017: OncoTargets and Therapy
https://www.readbyqxmd.com/read/28325358/seromucinous-ovarian-tumor-a-comparison-with-the-rest-of-ovarian-epithelial-tumors
#15
COMPARATIVE STUDY
Georgia Karpathiou, Celine Chauleur, Thomas Corsini, Melany Venet, Cyril Habougit, Freschia Honeyman, Fabien Forest, Michel Peoc'h
BACKGROUND: Seromucinous ovarian tumors are rare and not adequately described in the literature and this is especially true for seromucinous carcinomas. AIM OF THE STUDY: To describe histological and clinical features of these tumors in comparison with the rest of ovarian epithelial tumors. MATERIALS AND METHODS: Two hundred and forty one (241) ovarian tumors, borderline (n=92) or malignant (n=149), treated surgically without neoadjuvant chemotherapy, were examined...
April 2017: Annals of Diagnostic Pathology
https://www.readbyqxmd.com/read/28271744/an-exceptional-evolution-of-primary-peritoneal-serous-carcinoma
#16
Wala Ben Kridis, Syrine Sghaier, Nabil Toumi, Afef Khanfir, Jamel Daoud, Mounir Frikha
Primary peritoneal serous carcinoma (PPSC) is a rare malignancy of the peritoneum. Clinically and histopathologically, PPSC is similar to serous ovarian papillary carcinoma. Brain metastases (BM) from PPSC are exceedingly rare. We report here a new case of BM two years after complete remission from a PPSC, to make aware physicians about this entity. This case is exceptional; firstly given the rarity of this entity and secondly due to the good response after radiotherapy then systemic chemotherapy with Carboplatin and Paclitaxel...
March 8, 2017: Acta Clinica Belgica
https://www.readbyqxmd.com/read/28241108/external-quality-assurance-in-nongynecologic-cytology-the-australasian-experience
#17
Paul W Shield, Felicity Frost, Jo L Finnimore, R Gordon Wright, Margaret C Cummings
BACKGROUND: The Royal College of Pathologists of Australasia Cytopathology Quality Assurance Program has operated an external quality assurance program in nongynecologic cytopathology since 1993. Glass slide preparations of a wide range of nongynecologic cases were circulated to approximately 200 cytopathology laboratories in 16 countries. METHODS: General nongynecologic cytology cases were manufactured from residual specimens after routine diagnosis. Fine-needle aspiration (FNA) cases were made by sampling fresh tissue and making direct specimens...
February 27, 2017: Cancer
https://www.readbyqxmd.com/read/28238382/frequency-of-papillary-tubal-hyperplasia-pth-salpingoliths-and-transition-from-adenoma-to-borderline-ovarian-tumors-bot-a-systematic-analysis-of-74-bot-with-different-histologic-types
#18
Lars-Christian Horn, Karolin Angermann, Bettina Hentschel, Jens Einenkel, Anne Kathrin Höhn
Borderline ovarian tumors (BOT) arise from cystadenomas and represent a transition step within the development of low-grade ovarian carcinomas (Type I tumors). That pathway mirrors the adenoma-to-carcinoma sequence known for colorectal cancer. It has been suggested that papillary tubal hyperplasia (PTH) and salpingoliths may be associated with the development of BOT. To evaluate the frequency of the presence of benign cystadenoma and its transition to BOT in a given patient as well as the presence of PTH and salpingoliths we re-valuated in 74 consecutive cases of BOT with different histologic types...
February 6, 2017: Pathology, Research and Practice
https://www.readbyqxmd.com/read/28195111/squash-cytodiagnosis-of-synchronous-papillary-serous-carcinoma-of-ovary-and-endometrium-with-demonstration-of-serous-tubal-intraepithelial-carcinoma-as-a-precursor-lesion
#19
Asaranti Kar, Tushar Kar, Ipsita Dha, Sasmita Panda
No abstract text is available yet for this article.
January 2017: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/28162214/-the-role-of-hong-s-single-stitch-duct-to-mucosa-pancreaticojejunostomy-in-laparoscopic-pancreaticoduodenectomy
#20
D F Hong, Y H Liu, Y H Zhang, Y C Wang, Z M Wang, W D Wu, G L Shen, J G Zhang, W Zhang, J Cheng, S Y Peng
Objective: To investigate the role of "Hong's single-stitch duct to mucosa pancreaticojejunostomy(HSDMP)" in laparoscopic pancreaticoduodenectomy (LPD). Methods: The clinical data including perioperative and short-term outcomes of 51 cases of LPD with HSDMP which performed in Zhejiang Provincial People's Hospital(33 cases) and Frist Clinical Hospital of Jilin University(18 cases) between April and October 2016 were reviewed retrospectively. There were 31 male patients and 20 female patients. The mean age was(59±11)years...
February 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
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