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https://www.readbyqxmd.com/read/28629704/relationship-between-8-year-weight-change-body-size-and-health-in%C3%A2-a%C3%A2-large-cohort-of-adults-in-thailand
#1
Vasoontara Yiengprugsawan, Wimalin Rimpeekool, Keren Papier, Cathy Banwell, Sam-Ang Seubsman, Adrian C Sleigh
BACKGROUND: Overweight and obesity have been shown to be risk factors for a range of non-communicable diseases, especially cardio-metabolic conditions, worldwide. But less is known about the effects of weight change on adults' overall health and wellbeing, particularly in transitional low- and middle-income countries. This study aimed to assess the relationship between 8-year weight change and measures of self-assessed health among Thai adults. METHODS: Data were collected from Thai adults aged 25-40 years (n = 27,003) enrolled in the Thai cohort Study and surveyed in 2005, 2009, and 2013...
June 16, 2017: Journal of Epidemiology
https://www.readbyqxmd.com/read/28621751/geographic-variations-in-cardiometabolic-risk-factors-in-luxembourg
#2
Ala'a Alkerwi, Illiasse El Bahi, Saverio Stranges, Jean Beissel, Charles Delagardelle, Stephanie Noppe, Ngianga-Bakwin Kandala
Cardiovascular disease (CVD) and associated behavioural and metabolic risk factors constitute a major public health concern at a global level. Many reports worldwide have documented different risk profiles for populations with demographic variations. The objective of this study was to examine geographic variations in the top leading cardio metabolic and behavioural risk factors in Luxembourg, in order to provide an overall picture of CVD burden across the country. The analysis conducted was based on data from the nationwide ORISCAV-LUX survey, including 1432 subjects, aged 18-69 years...
June 16, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28621053/factors-affecting-aging-cognitive-function-among-community-dwelling-older-adults
#3
Chun-Ja Kim, JeeWon Park, Se-Won Kang, Elizabeth A Schlenk
AIM: The study purpose was to determine factors affecting aging cognitive function of 3,645 community-dwelling older adults in Korea. METHODS: The Hasegawa Dementia Scale assessed aging cognitive function, blood analyses and anthropometrics assessed cardio-metabolic risk factors, and the Geriatric Depression Scale Short Form Korean Version assessed depressive symptoms. RESULTS: Participants with poor aging cognitive function were more likely to be in the late age group (≥75 y) and currently smoking and have a medical history of stroke, high body mass index, and high level of depressive symptoms; they were also less likely to engage in regular meals and physical activities...
June 16, 2017: International Journal of Nursing Practice
https://www.readbyqxmd.com/read/28620441/impaired-wound-healing-facts-and-hypotheses-for-multi-professional-considerations-in-predictive-preventive-and-personalised-medicine
#4
REVIEW
Eden Avishai, Kristina Yeghiazaryan, Olga Golubnitschaja
Whereas the physiologic wound healing (WH) successfully proceeds through the clearly defined sequence of the individual phases of wound healing, chronic non-healing wounds/ulcers fail to complete the individual stages and the entire healing process. There are many risk factors both modifiable (such as stress, smoking, inappropriate alcohol consumption, malnutrition, obesity, diabetes, cardio-vascular disease, etc.) and non-modifiable (such as genetic diseases and ageing) strongly contributing to the impaired WH...
March 2017: EPMA Journal
https://www.readbyqxmd.com/read/28616825/correlation-of-cardio-metabolic-parameters-with-vitamin-d-status-in-healthy-premenopausal-women
#5
S Giovinazzo, A Alibrandi, A Campennì, F Trimarchi, R M Ruggeri
PURPOSE: Vitamin D has been associated with metabolic disorders and increasing risk of cardiovascular diseases, with conflicting results. Aim of our study was to evaluate the relationship, if any, between cardio-metabolic risk factors and serum 25(OH)D concentrations in healthy women in premenopausal age. METHODS: We enrolled 200 healthy women, aged 19-50 years (mean age ± SD, 38 ± 11 years). In each subject, we measured serum 25(OH)D in relation to metabolic biomarkers and cardiovascular parameters...
June 14, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/28611863/effect-of-azilsartan-on-day-to-day-variability-in-home-blood-pressure-a-prospective-multicenter-clinical-trial
#6
Toru Miyoshi, Ryoji Suetsuna, Naoto Tokunaga, Masayasu Kusaka, Ryuichiro Tsuzaki, Kazuya Koten, Kohno Kunihisa, Hiroshi Ito
BACKGROUND: The blood pressure variability (BPV) such as visit-to-visit, day-by-day, and ambulatory BPV has been also shown to be a risk of future cardiovascular events. However, the effects of antihypertensive therapy on BPV remain unclear. The purpose of this study was to evaluate the effect of azilsartan after switching from another angiotensin II receptor blocker (ARB) on day-to-day BPV in home BP monitoring. METHODS: This prospective, multicenter, open-labeled, single-arm study included 28 patients undergoing treatment with an ARB, which was switched to azilsartan after enrollment...
July 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28598564/withdrawn-celecoxib-for-rheumatoid-arthritis
#7
REVIEW
Sarah E Garner, Dogan Fidan, Ruth R Frankish, Maria Judd, Beverley Shea, Tanveer Towheed, Peter Tugwell, George A Wells
BACKGROUND: Rheumatoid arthritis (RA) is a systemic auto-immune disorder, involving persistent joint inflammation. NSAIDs are used to control the symptoms of RA, but are associated with significant gastro-intestinal toxicity, including a risk of potentially life threatening gastroduodenal perforations, ulcers and bleeds. The NSAIDs known as the selective Cox II inhibitors, of which celecoxib is a member, were developed in order to reduce the GI toxicity, but are more expensive. OBJECTIVES: To establish the efficacy and safety of celecoxib in the management of RA by systematic review of available evidence...
June 9, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28598045/soft-drinks-consumption-and-the-risk-of-nonalcoholic-fatty-liver-disease
#8
Zeba Siddiqi, Ritu Karoli, Jalees Fatima, Sachin Khanduri, Shishir Varshneya, Sara Sabina Ahmad
INTRODUCTION: The increased consumption of sugar-sweetened beverages (SSBs) has been implicated in the increased incidence of obesity and metabolic syndrome Little of the research on sugar-sweetened beverage intake has examined the consumption patterns of sugared beverages by college students, despite the vulnerabilities of this population to weight gain. The current study sought to characterize sugar-sweetened beverage intake of undergraduate students who belong to high socio-economic strata and to study its correlation with presence of non-alcoholic fatty liver disease...
May 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28594708/reference-values-of-cardio-ankle-vascular-index-in-a-random-sample-of-a-white-population
#9
Peter Wohlfahrt, Renata Cífková, Narine Movsisyan, Šárka Kunzová, Jiří Lešovský, Martin Homolka, Vladimír Soška, Petr Dobšák, Francisco Lopez-Jimenez, Ondřej Sochor
OBJECTIVES: Cardio-ankle vascular index (CAVI), a parameter of arterial stiffness, has been increasingly used for cardiovascular risk estimation. Currently used CAVI reference values are derived from the Japanese population. It is not clear whether the same reference values can be used in the white population. The aim of the present study was to describe cardiovascular risk factors influencing CAVI and to establish CAVI reference values. METHODS: A total of 2160 individuals randomly selected from the Brno city population aged 25-65 years were examined...
June 7, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28592789/are-sutureless-aortic-valves-suitable-for-severe-high-risk-patients-suffering-from-active-infective-aortic-valve-endocarditis
#10
Alexander Weymann, Johanna Konertz, Michael Laule, Karl Stangl, Pascal M Dohmen
BACKGROUND Sutureless aortic valves were introduced to facilitate minimally invasive aortic valve surgery. Since sutureless aortic valves are a feasible procedure, we evaluated if any benefits could be identified in severe high-risk patients with active infective endocarditis of the aortic valve. MATERIAL AND METHODS Between April 2014 and April 2015, a total of 42 patients received a sutureless Perceval® aortic valve (Sorin Biomedica Cardio Srl, Saluggia, Italy) for different indications. Nine of these patients (median age 71 years, range 47-83 years) suffered from active infective endocarditis, including four patients with prosthetic aortic valve endocarditis...
June 8, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28590346/associations-between-high-risk-alcohol-consumption-and-sarcopenia-among-postmenopausal-women
#11
Yu-Jin Kwon, Hyoung-Ji Lim, Yong-Jae Lee, Hye-Sun Lee, John A Linton, Jae Woo Lee, Hee-Taik Kang
OBJECTIVE: Sarcopenia is an age-related process, leading to cardio-metabolic diseases and disabilities. High-risk drinking is also closely related to diabetes, hypertension, and dyslipidemia, which are modifiable risk factors for sarcopenia. In the present study, we aimed to investigate the association between alcohol-drinking patterns and sarcopenia in Korean postmenopausal women. METHODS: Data from 2,373 postmenopausal women were analyzed from the 2008 to 2011 Korean National Health and Nutrition Examination Survey...
June 5, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28587527/comparison-of-intergrowth-21-and-fenton-growth-standards-to-assess-size-at-birth-and-extrauterine-growth-in-very-preterm-infants
#12
Funda Tuzun, Ebru Yucesoy, Bora Baysal, Abdullah Kumral, Nuray Duman, Hasan Ozkan
AIM: This study aimed to compare recently published prescriptive INTERGROWTH-21st standards with commonly used intrauterine based Fenton growth standards in terms of birth size classification and extrauterine growth restriction (EUGR) incidence in a sample of very preterm infants. METHOD: The anthropometric measures of preterm infants born before 32 weeks of gestation at the Dokuz Eylul University Hospital during the period from January 2012 to February 2016 were obtained at birth, at the 36th gestational weeks or at the time of discharge...
June 7, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28586605/burden-of-atherosclerosis-risk-among-different-ethinicity-a-hidden-health-challenge
#13
Tariq Ashraf, Kanwal Fatima Aamir, Abdul Samad Achakzai, Naeem Mengal, Muhammad Tariq Karim
OBJECTIVE: Atherosclerosis risk and incidence of developing chronic cardiovascular conditions vary greatly between ethnic groups in South Asian population. To evaluate different ethnic groups in Pakistan, population based study was conducted at Karachi, the largest metropolitan city of Pakistan; to assess ten years and lifetime estimated cardiovascular disease risks without preexisting cardiovascular disease in Pakistani subjects by using Pooled Cohort Risk equation (calculator) as per American College of Cardiology (ACC) and the American Heart Association (AHA) 2013 guidelines...
October 2016: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28585194/circadian-rhythms-in-diet-induced-obesity
#14
Atilla Engin
The biological clocks of the circadian timing system coordinate cellular and physiological processes and synchronizes these with daily cycles, feeding patterns also regulates circadian clocks. The clock genes and adipocytokines show circadian rhythmicity. Dysfunction of these genes are involved in the alteration of these adipokines during the development of obesity. Food availability promotes the stimuli associated with food intake which is a circadian oscillator outside of the suprachiasmatic nucleus (SCN)...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28585152/overview-of-the-safety-of-anti-vegf-drugs-analysis-of-the-italian-spontaneous-reporting-system
#15
Paola Maria Cutroneo, Claudia Giardina, Valentina Ientile, Simona Potenza, Laura Sottosanti, Carmen Ferrajolo, Costantino J Trombetta, Gianluca Trifirò
INTRODUCTION: Anti-vascular endothelial growth factor (anti-VEGF) drugs are widely used for the treatment of several cancers and retinal diseases. The systemic use of anti-VEGF drugs has been associated with an increased risk of serious adverse reactions. Whether this risk is also related to intravitreal administration of anti-VEGF drugs is unclear. OBJECTIVE: The aim of this study was to provide an overview of the safety of anti-VEGF drugs in oncology and ophthalmology settings using the Italian Spontaneous Reporting System (SRS)...
June 5, 2017: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
https://www.readbyqxmd.com/read/28575906/-preoperative-evaluation-of-adult-patients-before-elective-non-cardiothoracic-surgery
#16
(no author information available yet)
Evaluation of the patient's medical history and a physical examination are the cornerstones of risk assessment prior to elective surgery and may help to optimize the patient's preoperative medical condition and to guide perioperative management. Whether the performance of additional technical tests (e.g. blood chemistry, ECG, spirometry, chest x-ray) can contribute to a reduction of perioperative risk is often not very well known or controversial. Similarly, there is considerable uncertainty among anaesthesiologists, internists and surgeons with respect to the perioperative management of the patient's long-term medication...
June 2017: Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie: AINS
https://www.readbyqxmd.com/read/28575405/long-term-exposure-to-road-traffic-noise-ambient-air-pollution-and-cardiovascular-risk-factors-in-the-hunt-and-lifelines-cohorts
#17
Yutong Cai, Anna L Hansell, Marta Blangiardo, Paul R Burton, Kees de Hoogh, Dany Doiron, Isabel Fortier, John Gulliver, Kristian Hveem, Stéphane Mbatchou, David W Morley, Ronald P Stolk, Wilma L Zijlema, Paul Elliott, Susan Hodgson
Aims: Blood biochemistry may provide information on associations between road traffic noise, air pollution, and cardiovascular disease risk. We evaluated this in two large European cohorts (HUNT3, Lifelines). Methods and results: Road traffic noise exposure was modelled for 2009 using a simplified version of the Common Noise Assessment Methods in Europe (CNOSSOS-EU). Annual ambient air pollution (PM10, NO2) at residence was estimated for 2007 using a Land Use Regression model...
May 31, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28575229/the-relationship-between-the-score-on-a-simple-measure-of-cognitive-function-incident-cvd-in-people-with-diabetes-a-post-hoc-epidemiological-analysis-from-the-accord-mind-study
#18
Tali Cukierman-Yaffe, Hertzel C Gerstein, Michael E Miller, Lenore J Launer, Jeff Williamson, Karen R Horowitz, Faramarz Ismail-Beigi, Ronald M Lazar
Context and Objective: Diabetes is associated with a greater risk for incident cardio-vascular disease and for cognitive dysfunction. This study aimed to investigate, in people with Type 2 diabetes the association of a simple measure of cognitive function to CVD events and mortality. Design, Setting, Participants, Measurements & Outcomes: The ACCORD trial included persons with long-standing T2D. A sub-study of 2977 (MIND) participants age => 55 years aimed to test the effect of the interventions on brain structure and function...
June 1, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28575038/plasma-brain-derived-neurotrophic-factor-concentration-is-a-predictor-of-chronic-kidney-disease-in-patients-with-cardiovascular-risk-factors-hyogo-sleep-cardio-autonomic-atherosclerosis-study
#19
Masafumi Kurajoh, Manabu Kadoya, Akiko Morimoto, Akio Miyoshi, Akinori Kanzaki, Miki Kakutani-Hatayama, Kae Hamamoto, Takuhito Shoji, Yuji Moriwaki, Tetsuya Yamamoto, Masaaki Inaba, Mitsuyoshi Namba, Hidenori Koyama
BACKGROUND: Brain-derived neurotrophic factor (BDNF) has been shown to have protective effects against cardiovascular diseases and death through neural and non-neural pathways via tropomyosin-related kinase B signaling. However, it is not known whether plasma BDNF concentration is a predictor of chronic kidney disease (CKD). DESIGN: This study was conducted as a prospective cohort study as part of the Hyogo Sleep Cardio-Autonomic Atherosclerosis. METHODS: We measured plasma BDNF concentration in 324 patients without CKD, defined as an estimated glomerular filtration rate (eGFR) less than 60 ml/min/1...
2017: PloS One
https://www.readbyqxmd.com/read/28574979/antenatal-corticosteroids-and-cardio-metabolic-outcomes-in-adolescents-born-with-very-low-birth-weight
#20
Lisa K Washburn, Patricia A Nixon, Beverly M Snively, Gregory B Russell, Hossam A Shaltout, Andrew M South, T Michael O'Shea
BACKGROUND: Exposure to antenatal corticosteroids (ANCS) is associated with adverse cardio-metabolic outcomes in animal models; however long-term outcomes in clinical studies are not well characterized. We hypothesized that exposure to ANCS would be associated with markers of increased cardio-metabolic risk in adolescents born with very low birth weight (VLBW). METHODS: In an observational cohort of 186 VLBW 14-year-old adolescents we measured resting blood pressure (BP), BP response to cold, ambulatory BP, and anthropometrics; performed dual-energy X-ray absorptiometry; and analyzed blood samples for uric acid, cholesterol, glycated hemoglobin, and high-sensitivity C-reactive protein...
June 2, 2017: Pediatric Research
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