keyword
https://read.qxmd.com/read/38634670/factors-influencing-real-world-use-of-the-more-affected-upper-limb-after-stroke-a-scoping-review
#1
JOURNAL ARTICLE
Anadil Bayazeed, Ghaleb Almalki, Amjad Alnuaim, Mary Klem, Amit Sethi
IMPORTANCE: Current interventions are limited in improving use of the more-affected upper limb in real-world daily occupations and functional independence poststroke. A comprehensive understanding of the factors influencing real-world upper limb use is required to develop interventions to improve functional independence poststroke. OBJECTIVE: To systematically review the factors that influence real-world use of the more-affected upper limb poststroke. DATA SOURCES: We searched MEDLINE, Embase, PsycINFO, and the Physiotherapy Evidence Database for English-language articles from 2012 to 2023...
March 1, 2024: American Journal of Occupational Therapy: Official Publication of the American Occupational Therapy Association
https://read.qxmd.com/read/38634214/mandibular-molar-protraction-a-comparison-between-fixed-functional-appliances-and-temporary-anchorage-devices
#2
JOURNAL ARTICLE
Abdulrahman Alshehri, Sarah Abu Arqub, Anna Betlej, Aditya Chhibber, Sumit Yadav, Madhur Upadhyay
INTRODUCTION: This study aimed to compare the efficiency of temporary anchorage devices (TADs) and fixed functional appliances (FFAs) for mandibular molar protraction. METHODS: Orthodontic records of 1050 consecutively treated patients with molar protraction were screened. Thirty-six records (22 females and 14 males; mean age, 17.4 years) were divided into two groups: TAD (21 subjects with 25 edentulous spaces) and FFA (15 subjects with 24 edentulous spaces)...
April 18, 2024: Orthodontics & Craniofacial Research
https://read.qxmd.com/read/38632620/adherence-to-the-mediterranean-diet-can-beneficially-affect-the-gut-microbiota-composition-a-systematic-review
#3
Armin Khavandegar, Ali Heidarzadeh, Pooneh Angoorani, Shirin Hasani-Ranjbar, Hanieh-Sadat Ejtahed, Bagher Larijani, Mostafa Qorbani
AIM: Dietary patterns could have a notable role in shaping gut microbiota composition. Evidence confirms the positive impact of the Mediterranean diet (MD), as one of the most studied healthy dietary patterns, on the gut microbiota profile. We conducted this systematic review to investigate the results of observational studies and clinical trials regarding the possible changes in the gut microbiota composition, metabolites, and clinical outcomes following adherence to MD in healthy cases or patients suffering from metabolic disorders...
April 17, 2024: BMC Medical Genomics
https://read.qxmd.com/read/38632141/hoxb9-promotes-laryngeal-squamous-cell-carcinoma-progression-by-upregulating-mmp12
#4
JOURNAL ARTICLE
Chuanhui Sun, Hua Deng, Qiuying Li, Peng Wang, Yujiang Chen, Yanan Sun, Changsong Han
Transcriptional factor HOXB9, a part of the HOX gene family, plays a crucial role in the development of diverse cancer types. This study aimed to elucidate the regulatory mechanism of HOXB9 on the proliferation and invasion of laryngeal squamous cell carcinoma (LSCC) cells to provide guidance for the development and prognosis of LSCC. The CRISPR/Cas9 method was employed in LSCC cell lines to knock out the HOXB9 gene and validate its effects on the proliferation, migration, invasion, and regulation of LSCC cells...
April 18, 2024: Functional & Integrative Genomics
https://read.qxmd.com/read/38625548/functional-and-oncological-outcomes-after-right-hemisphere-glioma-resection-in-awake-versus-asleep-patients-a-systematic-review-and-meta-analysis
#5
REVIEW
Esteban Ramírez-Ferrer, Maria Paula Aguilera-Pena, Hugues Duffau
The right hemisphere has been underestimated by being considered as the non-dominant hemisphere. However, it is involved in many functions, including movement, language, cognition, and emotion. Therefore, because lesions on this side are usually not resected under awake mapping, there is a risk of unfavorable neurological outcomes. The goal of this study is to compare the functional and oncological outcomes of awake surgery (AwS) versus surgery under general anesthesia (GA) in supratentorial right-sided gliomas...
April 16, 2024: Neurosurgical Review
https://read.qxmd.com/read/38621342/proteomic-profiling-of-tumor-microenvironment-and-prognosis-risk-prediction-in-stage-i-lung-adenocarcinoma
#6
JOURNAL ARTICLE
Yueh-Feng Lu, Ya-Hsuan Chang, Yi-Ju Chen, Min-Shu Hsieh, Mong-Wei Lin, Hsao-Hsun Hsu, Chia-Li Han, Yu-Ju Chen, Sung-Liang Yu, Jin-Shing Chen, Hsuan-Yu Chen
OBJECTIVES: With the increasing popularity of CT screening, more cases of early-stage lung cancer are being diagnosed. However, 24.5% of stage I non-small-cell lung cancer (NSCLC) patients still experience treatment failure post-surgery. Biomarkers to predict lung cancer patients at high risk of recurrence are needed. MATERIALS AND METHODS: We collected protein mass spectrometry data from the Taiwan Lung Cancer Moonshot Project and performed bioinformatics analysis on proteins with differential expressions between tumor and adjacent normal tissues in 74 stage I lung adenocarcinoma (LUAD) cases, aiming to explore the tumor microenvironment related prognostic biomarkers...
April 12, 2024: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://read.qxmd.com/read/38615210/immediate-effect-of-physiotherapist-demonstrated-action-observation-with-execution-for-improving-upper-extremity-motor-function-in-stroke-a-pre-post-pilot-study
#7
JOURNAL ARTICLE
Shaj Shrestha, Nistha Shrestha, Abhishek Dhalachhe Shrestha, Shambhu Prasad Adhikari
BACKGROUND: Video-demonstrated action-observation-execution is an effective intervention for motor re-learning in stroke rehabilitation. But customization of video for each task repeatedly questions its feasibility within limited resources, particularly for daily routine practice and in community settings. Physiotherapist-demonstrated action-observation-execution is a practical intervention based on the principle of observation and consecutive repetitions of observed real, live movements...
March 22, 2024: Journal of Nepal Health Research Council
https://read.qxmd.com/read/38606538/the-effect-of-auto-generated-corrective-exercise-programming-on-movement-literacy-among-firefighters-a-pilot-study
#8
JOURNAL ARTICLE
Morey J Kolber, William J Hanney
INTRODUCTION: Approximately 50% of firefighter injuries occur in the musculoskeletal system. Poor movement quality increases injury risk, while movement-based interventions may reduce injuries. PURPOSE: Investigate the effectiveness of auto-generated exercise programming on movement literacy scores among firefighters with lower baseline Functional Movement System (FMS™) scores. METHODS: Eleven male firefighters (mean age 44) with FMS™ scores less than 14/21 were included...
April 12, 2024: Physiotherapy Theory and Practice
https://read.qxmd.com/read/38602630/effects-of-pilates-exercises-on-health-related-quality-of-life-in-postmenopausal-women-a-systematic-review-and-meta-analysis
#9
REVIEW
Priscila Peruzzolo de Almeida, Raphael Gonçalves de Oliveira, Laura Isabel Martins de Almeida, Laís Campos de Oliveira
OBJECTIVE: To verify the effects of Pilates exercises on health-related quality of life (HRQoL) in postmenopausal women. METHODS: A systematic search was conducted in the following databases: PubMed, Embase, CENTRAL, CINAHL, Web of Science, LILACS, SportDiscus, Scielo, and PEDro. Randomized clinical trials (RCTs) that intervened with Pilates and had HRQoL as an outcome were eligible. The methodological quality of each RCT was assessed using the PEDro scale and the certainty of the evidence using the GRADE system...
April 11, 2024: Quality of Life Research
https://read.qxmd.com/read/38601217/assessments-and-interventions-on-body-functions-structures-and-activity-to-prepare-adults-with-acute-spinal-cord-injury-or-disease-for-participation-a-scoping-review
#10
Sophie Irrgang, Sandra Himmelhaus, Kirstin Allek, Isabelle Debecker, Armin Gemperli, Karen Kynast, Anne von Reumont, Anke Scheel-Sailer
INTRODUCTION: In the acute phase after a spinal cord injury or disease (SCI/D), various therapeutic assessments and interventions are applied with the goal of restoring structures, preventing complications and preparing the patient as best as possible for further activity and finally participation. The goal was to identify and evaluate the available evidence on assessments and interventions for body functions and structures to prepare adults with acute spinal cord SCI/D for activity and participation during the first 14 days...
2024: Front Rehabil Sci
https://read.qxmd.com/read/38592302/the-impact-of-interaction-between-body-posture-and-movement-pattern-quality-on-injuries-in-amateur-athletes
#11
JOURNAL ARTICLE
Dawid Koźlenia, Katarzyna Kochan-Jacheć
Background : this study aimed to examine the impact of interaction between body posture and the quality of movement patterns on injury frequencies in amateur athletes. Methods : The study sample consisted of 89 young amateur athletes. Movement pattern quality was assessed by the Functional Movement Screen (FMS), test and body posture in the frontal plane was assessed by the moire method for the parameters Shoulder Slope Angle, Lower Scapula Protrusion Difference, and Pelvic Tilt Angle. Injury data were collected through completion of the Injury History Questionnaire for the past 12 months...
March 2, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38591193/cognitive-reserve-in-als-the-role-of-occupational-skills-and-requirements
#12
JOURNAL ARTICLE
Emma Rhodes, Sebleh Alfa, Hannah A Jin, Lauren Massimo, Lauren Elman, Defne Amado, Michael Baer, Colin Quinn, Corey T McMillan
OBJECTIVE: Amyotrophic Lateral Sclerosis (ALS) is a heterogeneous neurodegenerative condition featuring variable degrees of motor and cognitive impairment. We assessed the impact of specific, empirically derived occupational skills and requirements on cognitive and motor functioning in ALS. METHODS: Individuals with ALS (n = 150) were recruited from the University of Pennsylvania's Comprehensive ALS Clinic. The Edinburgh Cognitive and Behavioral ALS Screen (ECAS) measured cognition, and the Penn Upper Motor Neuron (PUMNS) and ALS Functional Rating Scales (ALSFRS-R) measured motor symptoms...
April 9, 2024: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
https://read.qxmd.com/read/38589907/cdc45-promotes-the-stemness-and-metastasis-in-lung-adenocarcinoma-by-affecting-the-cell-cycle
#13
JOURNAL ARTICLE
Yafeng Liu, Tao Han, Zhi Xu, Jing Wu, Jiawei Zhou, Jianqiang Guo, Rui Miao, Yingru Xing, Deyong Ge, Ying Bai, Dong Hu
OBJECTIVE: This study aimed to assess the functions of cell division cycle protein 45 (CDC45) in Non-small cell lung cancer (NSCLC) cancer and its effects on stemness and metastasis. METHODS: Firstly, differentially expressed genes related to lung cancer metastasis and stemness were screened by differential analysis and lasso regression. Then, in vitro, experiments such as colony formation assay, scratch assay, and transwell assay were conducted to evaluate the impact of CDC45 knockdown on the proliferation and migration abilities of lung cancer cells...
April 8, 2024: Journal of Translational Medicine
https://read.qxmd.com/read/38579603/cortactin-interacts-with-%C3%AE-dystrobrevin-1-and-regulates-murine-neuromuscular-junction-morphology
#14
JOURNAL ARTICLE
Teresa De Cicco, Marcin Pęziński, Olga Wójcicka, Bhola Shankar Pradhan, Margareta Jabłońska, Klemens Rottner, Tomasz J Prószyński
Neuromuscular junctions transmit signals from the nervous system to skeletal muscles, triggering their contraction, and their proper organization is essential for breathing and voluntary movements. αDystrobrevin-1 is a cytoplasmic component of the dystrophin-glycoprotein complex and has pivotal functions in regulating the integrity of muscle fibers and neuromuscular junctions. Previous studies identified that αDystrobrevin-1 functions in the organization of the neuromuscular junction and that its phosphorylation in the C-terminus is required in this process...
March 31, 2024: European Journal of Cell Biology
https://read.qxmd.com/read/38576829/effects-of-nontraditional-division-iii-lacrosse-participation-on-movement-pattern-quality-and-dynamic-postural-control
#15
JOURNAL ARTICLE
Christopher Rosenborough, Sean M Collins, Edward Smith, Thomas G Bowman
BACKGROUND/PURPOSE: No studies have observed the effects of a collegiate lacrosse season on movement pattern quality, dynamic postural control, or the accuracy of athletes' perceived movement pattern quality. The purpose was to examine the effects of a nontraditional fall season on movement pattern quality, perceived movement pattern quality, and dynamic postural control in collegiate lacrosse athletes. DESIGN: Cross-sectional laboratory study. METHODS: Fifty men's (age=19...
2024: International Journal of Sports Physical Therapy
https://read.qxmd.com/read/38570113/both-gain-and-loss-of-function-variants-of-kcna1-are-associated-with-paroxysmal-kinesignic-dyskinesia
#16
JOURNAL ARTICLE
Wan-Bing Sun, Jing-Xin Fu, Yu-Lan Chen, Hong-Fu Li, Zhi-Ying Wu, Dian-Fu Chen
KCNA1 is the coding gene for Kv1.1 voltage-gated potassium channel α subunit. Three variants of KCNA1 have been reported to manifest as paroxysmal kinesignic dyskinesia (PKD), but the correlation between them remains unclear due to the phenotypic complexity of KCNA1 variants as well as the rarity of PKD cases. Using the whole exome sequencing followed by Sanger sequencing, we screen potential pathogenic KCNA1 variants in patients clinically diagnosed with paroxysmal movement disorders and identify three previously unreported missense variants of KCNA1 in three unrelated Chinese families...
April 1, 2024: Journal of Genetics and Genomics
https://read.qxmd.com/read/38560024/mri-brain-structural-and-functional-networks-changes-in-parkinson-disease-with-rem-sleep-behavior-disorders
#17
JOURNAL ARTICLE
Fang Wang, Zhigang Zhu, Chuanbin Zhou, Yongyun Zhu, Yangfan Zhu, Chunyu Liang, Jieyu Chen, Bin Liu, Hui Ren, Xinglong Yang
BACKGROUND: Rapid eye movement sleep behavior disorder (RBD) is common in individuals with Parkinson's disease (PD). In spite of that, the precise mechanism underlying the pathophysiology of RBD among PD remains unclear. OBJECTIVE: The aim of the present study was to analyze gray matter volumes (GMVs) as well as the changes of functional connectivity (FC) among PD patients with RBD (PD-RBD) by employing a combination of voxel-based morphometry (VBM) and FC methods...
2024: Frontiers in Aging Neuroscience
https://read.qxmd.com/read/38558512/systematic-review-on-effects-of-experimental-orthodontic-tooth-displacement-on-brain-activation-assessed-by-fmri
#18
REVIEW
Gelareh Sadvandi, Amir Ehsan Kianfar, Kathrin Becker, Alexander Heinzel, Michael Wolf, Sareh Said-Yekta Michael
BACKGROUND: Orthodontic treatment is often accompanied by discomfort and pain in patients, which are believed to be a result of orthodontic tooth displacement caused by the mechanical forces exerted by the orthodontic appliances on the periodontal tissues. These lead to change blood oxygen level dependent response in related brain regions. OBJECTIVE: This systematic review aims to assess the impact of experimental orthodontic tooth displacement on alterations in central nervous system activation assessed by tasked based and resting state fMRI...
April 2024: Clinical and Experimental Dental Research
https://read.qxmd.com/read/38557618/continuous-motion-intention-prediction-using-semg-for-upper-limb-rehabilitation-a-systematic-review-of-model-based-and-model-free-approaches
#19
JOURNAL ARTICLE
Zijun Wei, Zhi-Qiang Zhang, Sheng Quan Xie
Upper limb functional impairments persisting after stroke significantly affect patients' quality of life. Precise adjustment of robotic assistance levels based on patients' motion intention using sEMG signals is crucial for active rehabilitation. This paper systematically reviews studies over the past decade on continuous prediction of upper limb single joint and multi-joint combinations motion intention using Model-Based (MB) and Model-Free (MF) approaches, based on 186 relevant studies screened from six major electronic databases...
April 1, 2024: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://read.qxmd.com/read/38545664/pediatric-performance-based-outcome-measures-for-upper-extremity-function-a-scoping-review-and-linking-to-the-international-classification-of-functioning-disability-and-health
#20
JOURNAL ARTICLE
Caroline Elfassy, Clarice Ribeiro Soares Araújo, Tessah Dunn, Sarah Cachecho, Rose Elekanachi, Johanne Higgins, Laurie Snider, Noemi Dahan-Oliel
Background. Performance-based outcome measures (PBOMs) are objective measures that assess physical capacity or performance in specific tasks or movements. Purpose. 1) to identify which PBOMs are most frequently reported to evaluate upper extremity (UE) function in pediatric rehabilitation 2) to determine the link between constructs of the ICF and meaningful concepts extracted from each identified PBOM. Methods. Pediatric UE PBOMs were searched in four databases. The selection of outcome measures included an initial title and abstract screening, followed by full-text review of the articles to be included based on identified selection criteria...
March 28, 2024: Canadian Journal of Occupational Therapy. Revue Canadienne D'ergothérapie
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