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chronic pelvic pain

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https://www.readbyqxmd.com/read/29778086/pelvic-floor-physical-therapy-and-women-s-health-promotion
#1
REVIEW
Samantha Lawson, Ashley Sacks
Pelvic floor dysfunction is defined as abnormal function of the pelvic floor and includes conditions that can have significant adverse impacts on a woman's quality of life, including urinary incontinence (stress, urge, and mixed), fecal incontinence, pelvic organ prolapse, sexual dysfunction, diastasis recti abdominis, pelvic girdle pain, and chronic pain syndromes. Women's health care providers can screen for, identify, and treat pelvic floor dysfunction. This article examines the case of a woman with multiple pelvic-floor-related problems and presents the evidence for the use of pelvic floor physical therapy (PFPT) for pregnancy-related pelvic floor dysfunction...
May 19, 2018: Journal of Midwifery & Women's Health
https://www.readbyqxmd.com/read/29774940/-prognostic-analysis-and-clinicopathological-features-of-20-patients-with-appendiceal-neuroendocrine-neoplasms
#2
Weilin Mao, Yang Lyu, Ning Pu, Jian'ang Li, Baobao Xin, Wenqi Chen, Dayong Jin, Wenhui Lou, Xuefeng Xu
OBJECTIVE: To investigate clinicopathological features and prognostic factors of appendiceal neuroendocrine neoplasms(a-NEN). METHODS: Clinical data of 20 patients diagnosed with a-NEN at Zhongshan Hospital of Fudan University between January 2000 and December 2016 were retrospectively analyzed. Pathological diagnosis was based on the WHO classification criteria of digestive system tumors (2010 edition). Based on the mitotic count and Ki-67 index, a-NENs were divided into grade 1 neuroendocrine tumor (NET G1), grade 2(G2) NET G2) and grade 3 (neuroendocrine carcinoma, NEC)...
May 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29763654/obturator-neuromodulation-with-laparoscopic-placement-of-an-obturator-lead-for-the-treatment-of-intractable-opioid-dependent-chronic-pelvic-pain-due-to-obturator-neuralgia
#3
Richard P Marvel
Chronic pelvic pain(CPP) is a common condition in women that can have a devastating effect on quality of life. Some of the most severe forms of CPP are related to peripheral nerve injuries causing persistent neuropathic pain. This is a case of a young woman with severe opioid dependent chronic pelvic and right groin pain due to obturator neuralgia. She had failed a multitude of treatments including multiple medications, manual physical therapy, nerve blocks, surgical neurolysis and spinal cord stimulation without significant benefit...
May 12, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29757454/non-pharmacological-interventions-for-treating-chronic-prostatitis-chronic-pelvic-pain-syndrome
#4
REVIEW
Juan Va Franco, Tarek Turk, Jae Hung Jung, Yu-Tian Xiao, Stanislav Iakhno, Virginia Garrote, Valeria Vietto
BACKGROUND: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a common disorder in which the two main clinical features are pelvic pain and lower urinary tract symptoms. There are currently many approaches for its management, using both pharmacological and non-pharmacological interventions. The National Institute of Health - Chronic Prostatitis Symptom Index (NIH-CPSI) score is a validated measure commonly used to measure CP/CPPS symptoms. OBJECTIVES: To assess the effects of non-pharmacological therapies for chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS)...
May 12, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29757068/physiotherapy-interventions-for-patients-with-chronic-pelvic-pain-a-systematic-review-of-the-literature
#5
Pedro Fuentes-Márquez, Irene Cabrera-Martos, Marie Carmen Valenza
OBJECTIVE: To summarize the available scientific evidence on physiotherapy interventions in the management of chronic pelvic pain (CPP). DATA SOURCES: A systematic review of randomized controlled trials was performed. An electronic search of MEDLINE, CINAHL, and Web of Science databases was performed to identify relevant randomized trials from 2010-2016. STUDY SELECTION: Manuscripts were included if at least one of the comparison groups received a physiotherapy intervention...
May 14, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29746393/female-veterans-with-diagnoses-of-both-chronic-pelvic-pain-and-overactive-bladder-how-do-they-compare-to-women-diagnosed-with-interstitial-cystitis
#6
Katherine A Volpe, Sara B Cichowski, Yuko K Komesu, Rebecca G Rogers, Allison Murata, Glen Murata
OBJECTIVE: The objective of this study was to compare women with a known diagnosis of interstitial cystitis (IC) to a population that might be at risk for the diagnosis of IC, women with diagnoses of both chronic pelvic pain (CPP) and overactive bladder (OAB). METHODS: We conducted a retrospective study of data from the Veterans Affairs Corporate Data Warehouse. The cohort included all female veterans who had established care with a primary care provider from 1997 to present...
May 10, 2018: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/29739958/trpv1-and-the-mcp-1-ccr2-axis-modulate-post-uti-chronic-pain
#7
John M Rosen, Ryan E Yaggie, Patrick J Woida, Richard J Miller, Anthony J Schaeffer, David J Klumpp
The etiology of chronic pelvic pain syndromes remains unknown. In a murine urinary tract infection (UTI) model, lipopolysaccharide of uropathogenic E. coli and its receptor TLR4 are required for post-UTI chronic pain development. However, downstream mechanisms of post-UTI chronic pelvic pain remain unclear. Because the TRPV1 and MCP-1/CCR2 pathways are implicated in chronic neuropathic pain, we explored their role in post-UTI chronic pain. Mice were infected with the E. coli strain SΦ874, known to produce chronic allodynia, and treated with the TRPV1 antagonist capsazepine...
May 8, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29737087/-expression-of-nerve-growth-factor-and-type-3-of-acid-sensitive-ion-channels-in-rat-model-of-type-%C3%A2-prostatitis
#8
Ming-Xing Zheng, Xiao-Dong Liu, Shi-Cheng Fan, Xin-Long Yu, Bo Zhu, Jie Shen
OBJECTIVE: To investigate the expressions of nerve growth factor (NGF) and acid-sensing ion channel 3 (ASIC3) in prostatic tissue of experimental rats with type Ⅲ prostatitis. METHODS: Thirty SD rats were randomly allocated into control group and experimental group. The rats in control group were subjected to pelvic and bilateral scapular subcutaneous injections of 0.9% sodium chloride,while the rats in experimental group were given pelvic and bilateral scapular subcutaneous injections of mixed suspension of complete Freund's adjuvant and prostatic tissue to induce autoimmune prostatitis (EAP)...
January 2018: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/29733841/abdominal-skeletal-muscle-activity-precedes-spontaneous-menstrual-cramping-pain-in-primary-dysmenorrhea
#9
Folabomi A Oladosu, Frank F Tu, Saaniya Farhan, Ellen F Garrison, Nicole D Steiner, Genevieve E Roth, Kevin M Hellman
BACKGROUND: Dysmenorrhea is a pervasive pain condition that affects 20-50% of reproductive-aged women. Distension of a visceral organ, such as the uterus, could elicit a viscero-motor reflex resulting in involuntary skeletal muscle activity and referred pain. Although referred abdominal pain mechanisms can contribute to visceral pain, the role of abdominal muscle activity has not yet been investigated within the context of menstrual pain. OBJECTIVE: The goal of this study is to determine if involuntary abdominal muscle activity precedes spontaneous episodes of menstrual cramping pain in dysmenorrheic women and if naproxen administration affects abdominal muscle activity...
May 4, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29733836/acupuncture-for-chronic-prostatitis-chronic-pelvic-pain-syndrome-a-randomized-sham-acupuncture-controlled-trial
#10
Zongshi Qin, Zhiwei Zang, Kehua Zhou, Jiani Wu, Jing Zhou, Joey S W Kwong, Zhishun Liu
PURPOSE: To investigate the effectiveness of acupuncture for patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). MATERIALS AND METHODS: We conducted this 32-week (8 weeks of treatment followed by 24 weeks of follow-up) randomized controlled trial comparing acupuncture with sham acupuncture. Participants with CP/CPPS were randomly assigned to acupuncture or non-invasive sham acupuncture. The primary outcome was the change in the National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) total score from baseline to week 8...
May 4, 2018: Journal of Urology
https://www.readbyqxmd.com/read/29732211/efficacy-of-sertraline-and-gabapentin-in-the-treatment-of-urethral-pain-syndrome-retrospective-results-of-a-single-institutional-cohort
#11
Özer Ural Cakici, Nurullah Hamidi, Emre Ürer, Emrah Okulu, Onder Kayigil
Introduction: Urethral pain syndrome is a subgroup of chronic pelvic pain syndromes and comprises a relatively challenging patient group in urological practice. Several different treatments have been used for the management of the condition from a mostly empirical basis. In this article, we present the results of a small cohort of young male patients treated with sertraline and gabapentin therapy. Material and methods: The data of 52 patients was retrospectively evaluated and 31 patients' data was included in this study...
2018: Central European Journal of Urology
https://www.readbyqxmd.com/read/29731970/elevated-seminal-plasma-estradiol-and-epigenetic-inactivation-of-esr1-and-esr2-is-associated-with-cp-cpps
#12
Nils Nesheim, Stuart Ellem, Temuujin Dansranjavin, Christina Hagenkötter, Elena Berg, Rupert Schambeck, Hans-Christian Schuppe, Adrian Pilatz, Gail Risbridger, Wolfgang Weidner, Florian Wagenlehner, Undraga Schagdarsurengin
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is associated with urinary tract symptoms and hormonal imbalances amongst others. The heterogeneous clinical presentation, unexplored molecular background and lack of prostate biopsies complicate therapy. Here, using liquid biopsies, we performed a comprehensive translational study on men diagnosed with CP/CPPS type III ( n = 50; median age 39.8, range 23-65) and age-matched controls ( n = 61; median age 36.8, range 20-69), considering biochemical parameters of blood and ejaculates, and epigenetic regulation of the estrogen receptor genes ( ESR1 and ESR2 ) in leukocytes isolated from blood (systemic regulation) and in somatic cells isolated from ejaculates (local regulation)...
April 13, 2018: Oncotarget
https://www.readbyqxmd.com/read/29730970/spinal-glial-adaptations-occur-in-a-minimally-invasive-mouse-model-of-endometriosis-potential-implications-for-lesion-etiology-and-persistent-pelvic-pain
#13
Kelsi N Dodds, Elizabeth A H Beckett, Susan F Evans, Mark R Hutchinson
Glial adaptations within the central nervous system are well known to modulate central sensitization and pain. Recently, it has been suggested that activity of glial-related proinflammatory cytokines may potentiate peripheral inflammation, via central neurogenic processes. However, a role for altered glial function has not yet been investigated in the context of endometriosis, a chronic inflammatory condition in women associated with peripheral lesions, often manifesting with persistent pelvic pain. Using a minimally invasive mouse model of endometriosis, we investigated associations between peripheral endometriosis-like lesions and adaptations in central glial reactivity...
January 1, 2018: Reproductive Sciences
https://www.readbyqxmd.com/read/29723461/-related-immunologic-mechanisms-of-chronic-prostatitis-advances-in-studies
#14
REVIEW
Yi Liu, Xian-Guo Chen, Chao-Zhao Liang
Chronic prostatitis is a common male disease with a high incidence rate and a serious impact on the patients' quality of life. The pathogenesis of chronic prostatitis remains unclear though it is considered to be possibly related to infection, inflammation, and abnormal pelvic nerve muscle activity. Recently, a growing number of studies have reported immune imbalance and changes of inflammatory cytokines in patients with chronic prostatitis as well as a close correlation of abnormal immune response with the occurrence of diseases, pelvic pain symptoms, mental symptoms, hyperalgesia, and so on...
July 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
https://www.readbyqxmd.com/read/29721332/a-pilot-randomised-double-blind-controlled-trial-of-the-efficacy-of-purified-fatty-acids-for-the-treatment-of-women-with-endometriosis-associated-pain-purfect-study-protocol
#15
Ibtisam M Abokhrais, Philippa T K Saunders, Fiona C Denison, Ann Doust, Linda Williams, Andrew W Horne
Background: Endometriosis affects 6-10% of women and is associated with debilitating pelvic pain. It costs the UK > £2.8 billion per year in loss of productivity. Endometriosis can be managed by surgical excision or medically by ovarian suppression. However, ~ 75% symptoms recur after surgery and available medical treatments have undesirable side effects and are contraceptive. Omega-3 purified fatty acids (PUFA) have been shown in animal models to reduce factors that are thought to lead to endometriosis-associated pain, have minimal side effects, and no effects on fertility...
2018: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/29704486/identification-of-experimental-bladder-sensitivity-among-dysmenorrhea-sufferers
#16
Kevin M Hellman, Avisek Datta, Nicole D Steiner, Julia N Kane Morlock, Ellen F Garrison, Daniel J Clauw, Frank F Tu
BACKGROUND: Dysmenorrhea is a common risk factor for chronic pain conditions including bladder pain syndrome. Few studies have formally evaluated asymptomatic bladder pain sensitivity in dysmenorrhea, and whether this largely reflects excess pelvic symptom reporting due to comorbid psychological dysfunction. OBJECTIVE: We sought to determine whether bladder hypersensitivity is more common among women reporting moderate or greater dysmenorrhea, without chronic pain elsewhere, after accounting for anxiety and depression...
April 25, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29702268/vascular-entrapment-of-both-the-sciatic-and-pudendal-nerve-causing-persistent-sciatica-and-pudendal-neuralgia
#17
Ahmet Kale, Gulfem Basol, Taner Usta, Isa Cam
STUDY OBJECTIVE: To demonstrate the laparoscopic approach to malformed branches of the vessels entrapping the nerves of the sacral plexus. DESIGN: A step-by-step explanation of the surgery using video (instructive video). The Ethics Committee ruled that approval was not required for this video. SETTING: Derince Education and Research Hospital, Turkey PATIENT: : The 26-year-old patient who had failed the medical therapy, complained about numbness and burning pain on the right side of the vagina and pain radiating to the lower limb for approximately 36 months period...
April 24, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29701391/diagnostic-challenges-in-chronic-constrictive-pericarditis
#18
Ana Braga, Afonso Oliveira, Kevin Domingues, Maria João Andrade, Miguel Abecacis, José Pedro Neves
INTRODUCTION: Chronic constrictive pericarditis (CCP) is a disease that has multiple possible causes and is associated with variable clinical findings, depending on its severity. It develops insidiously, and in many cases, particularly in developed countries, no antecedent diagnosis can be found. These cases are termed idiopathic. Tuberculosis is the leading cause of constrictive pericarditis in developing nations but represents only a small minority in developed countries. METHODS: Here the authors describe two different case reports where tuberculosis was the probable cause of CCP...
July 2017: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
https://www.readbyqxmd.com/read/29698941/computer-assisted-quantitative-assessment-of-prostatic-calcifications-in-patients-with-chronic-prostatitis
#19
Matteo Boltri, Vittorio Magri, Emanuele Montanari, Gianpaolo Perletti, Alberto Trinchieri
BACKGROUND: The aim of this study was the development of quantitative assessment of prostatic calcifications at prostatic ultrasound examination by the use of an image analyzer. MATERIALS AND METHODS: A group of 82 patients was evaluated by medical history, physical, and transrectal ultrasound examination. Patients had a urethral swab, a 4-specimen study and culture of the seminal fluid. Patients were classified according to National Institute of Diabetes and Digestive and Kidney Diseases/National Institutes of Health...
April 26, 2018: Urologia Internationalis
https://www.readbyqxmd.com/read/29697935/encrusted-cystitis-caused-by-corynebacterium-urealyticum-a-case-report-with-novel-treatment-strategy-of-intravesical-dimethyl-sulfoxide
#20
Tayyar Alp Ozkan, Mustafa Savas Yalcin, Ozdal Dillioglugil, Ibrahim Cevik
Encrusted cystitis (EC) was first described as chronic cystitis with mucosal calcification in 1914 (1). It is a very rare chronic inflammatory disease presenting with dysuria, pelvic pain and gross hematuria. Voided urine contains mucus or calcified mucopurulent stone like particles. Urinalysis always reveals alkaline pH. It may be present in healthy individuals with no predisposing etiological factors (2-4). Etiologically, previous urological diseases, immunosuppression, urinary infection with urea splitting bacteria, or urological interventions resulting in bladder mucosa trauma may also be present (5, 6)...
April 15, 2018: International Braz J Urol: Official Journal of the Brazilian Society of Urology
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