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https://www.readbyqxmd.com/read/29040512/fertility-related-knowledge-and-reproductive-goals-in-childhood-cancer-survivors-short-communication
#1
V Lehmann, M C Keim, L Nahata, E L Shultz, J L Klosky, M A Tuinman, C A Gerhardt
STUDY QUESTION: Do young adult survivors of childhood cancer know their fertility status, in the context of their parenthood goals and screening for gonadal functioning? SUMMARY ANSWER: While 80% of survivors (who were without children) wanted children in the future, most did not know their fertility status, and screening for gonadal functioning was underutilized. WHAT IS KNOWN ALREADY: Survivors of childhood cancer are at risk for infertility, but fertility counseling and assessment are underutilized...
September 29, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29036230/predictors-of-adverse-drug-reaction-related-hospitalisation-in-southwest-ethiopia-a-prospective-cross-sectional-study
#2
Mulugeta Tarekegn Angamo, Colin Michael Curtain, Leanne Chalmers, Daniel Yilma, Luke Bereznicki
BACKGROUND: Adverse drug reactions (ADRs) are important causes of morbidity and mortality in the healthcare system; however, there are no studies reporting on the magnitude and risk factors associated with ADR-related hospitalisation in Ethiopia. OBJECTIVES: To characterise the reaction types and the drugs implicated in admission to Jimma University Specialized Hospital, Southwest Ethiopia, and to identify risk factors associated with ADR-related hospitalisation...
2017: PloS One
https://www.readbyqxmd.com/read/29035141/usual-care-for-maltreatment-related-pediatric-posttraumatic-stress-disorder-in-germany
#3
Annika Münzer, Rita Rosner, Helene Gertrud Ganser, Alexander Naumann, Paul Lukas Plener, Andreas Witt, Lutz Goldbeck
Child maltreatment represents a major risk factor for the development of emotional and behavioral problems, especially posttraumatic stress disorder (PTSD). While effective trauma-focused treatments are available, little is known about the usual mental healthcare for abused youths in Germany. The present study compared the utilization of mental healthcare in abused youths who had developed a PTSD (N = 95) with a group presenting other mental disorders (N = 146). Semistructured interviews were used to assess maltreatment histories, current mental health, and healthcare utilization...
October 16, 2017: Zeitschrift Für Kinder- und Jugendpsychiatrie und Psychotherapie
https://www.readbyqxmd.com/read/29031760/impact-of-diagnosing-and-treating-obstructive-sleep-apnea-on-healthcare-utilization
#4
Robert J Walter, Scott I Hagedorn, Christopher J Lettieri
PURPOSE: Obstructive sleep apnea (OSA) contributes to an increased risk for multiple co-morbidities and decreased quality of life. As a result, OSA patients may have higher usage of healthcare resources which can be mitigated with effective treatment. This study evaluates changes in healthcare utilization (HCU) following the initiation of therapy for OSA. METHODS: We conducted a retrospective study of newly diagnosed OSA patients. To assess total HCU, we incorporated the sum total of outpatient clinic encounters, laboratory tests, and medication prescriptions into a composite HCU score...
October 2017: Sleep Medicine
https://www.readbyqxmd.com/read/29030268/topical-vancomycin-to-reduce-surgical-site-infections-in-neurosurgery-study-protocol-for-a-multi-center-randomized-controlled-trial
#5
Alexander J Jonokuchi, Jared Knopman, Ryan E Radwanski, Moises A Martinez, Blake Eaton Samuel Taylor, Michael Rothbaum, Sean Sullivan, Trae R Robison, Brandon R Christophe, Dimitri Sigounas, Brett Youngerman, Emilia Bagiella, Peter D Angevine, Franklin D Lowy, E Sander Connolly
Surgical-site infections (SSIs) account for 20% of all healthcare-associated infections, are the most common nosocomial infection among surgical patients, and are a focus of quality improvement initiatives. Despite implementation of many quality care measures (e.g. prophylactic antibiotics), SSIs remain a significant cause of morbidity, mortality, and economic burden, particularly in the field of neurosurgery. Topical vancomycin is increasingly utilized in instrumented spinal and cardiothoracic procedures, where it has been shown to reduce the risk of SSIs...
October 10, 2017: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/29028958/development-of-clinical-prediction-models-for-surgery-and-complications-in-crohn-s-disease
#6
Leonardo Guizzetti, Guangyong Zou, Reena Khanna, Parambir S Dulai, William J Sandborn, Vipul Jairath, Brian G Feagan
Background and Aims: Crohn's disease-related complications account for a substantial proportion of inflammatory bowel disease-associated healthcare expenditure. Identifying patients at risk for complications may allow for targeted use of early therapeutic interventions to off-set this natural course. We aimed to develop risk prediction models for Crohn's disease-related surgery and complications. Methods: Using data from the Randomized Evaluation of an Algorithm for Crohn's Disease cluster-randomized clinical Trial (REACT), which involved 1898 patients from 40 community practices...
September 19, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/29028917/comparative-usability-of-modern-anaesthesia-ventilators-a-human-factors-study
#7
J Spaeth, T Schweizer, A Schmutz, H Buerkle, S Schumann
Background: The anaesthesia ventilator represents the key equipment for intraoperative respiratory care. Improper operation of this device may threaten a patient's health. A self-explanatory interface facilitates handling and decreases the risk of operating errors. This study systematically evaluates the usability of user interfaces in four modern anaesthesia ventilators. Methods: Twenty naïve operators were asked to execute 20 tasks on each of four different anaesthesia ventilators (Avance CS2™, GE Healthcare; Flow-i™, Maquet; and Perseus™ and Primus™, Dräger) in a randomized order...
October 3, 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29028760/the-impact-of-metastatic-spinal-tumor-location-on-30-day-perioperative-mortality-and-morbidity-after-surgical-decompression
#8
Awais K Hussain, Khushdeep S Vig, Zoe B Cheung, Kevin Phan, Mauricio C Lima, Jun S Kim, Deepak A Kaji, Varun Arvind, Samuel Kang-Wook Cho
STUDY DESIGN: A retrospective cohort study from 2011 to 2014 was performed using the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database. OBJECTIVE: The purpose of this study was to assess the impact of tumor location in the cervical, thoracic, or lumbosacral spine on 30-day perioperative mortality and morbidity after surgical decompression of metastatic extradural spinal tumors. SUMMARY OF BACKGROUND DATA: Operative treatment of metastatic spinal tumors involves extensive procedures that are associated with significant complication rates and healthcare costs...
October 12, 2017: Spine
https://www.readbyqxmd.com/read/29027621/use-of-carboxyhemoglobin-as-a-biomarker-of-environmental-co-exposure-critical-evaluation-of-the-literature
#9
Agnese Veronesi, Valentina Pecoraro, Stefano Zauli, Marta Ottone, Giovanni Leonardi, Paolo Lauriola, Tommaso Trenti
Carbon monoxide (CO) poisoning is the primary cause for access to emergency department (ED) services for more than 50,000 persons in Europe and the USA every year. CO poisoning diagnosis is based on multiple factors and is usually confirmed by high carboxyhemoglobin (COHb) levels in the blood. We conducted a systematic evaluation of literature to investigate the usefulness of COHb as a biomarker of environmental CO exposure. We conducted an electronic search in Medline, Embase, and the Cochrane Library databases...
October 13, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29027496/optimizing-usability-and-signal-capture-a-proactive-risk-assessment-for-the-implementation-of-a-wireless-vital-sign-monitoring-system
#10
Rebecca Kowalski, Muge Capan, Peter Lodato, Danielle Mosby, Tamekia Thomas, Ryan Arnold, Kristen Miller
Wearable vital sign monitors are a promising step towards optimal patient surveillance, providing continuous data to allow for early detection and treatment of patient deterioration. However, as wearable monitors become more widely adopted in healthcare, there is a corresponding need to carefully design the implementation of these tools to promote their integration into clinical workflows and defend against potential misuse and patient harm. Prior to the roll-out of these monitors, our multidisciplinary team of clinicians, clinical engineers, information technologists and research investigators conducted a modified Healthcare Failure Mode and Effect Analysis (HFMEA), a proactive evaluation of potential problems which could be encountered in the use of a wireless vital signs monitoring system...
October 13, 2017: Journal of Medical Engineering & Technology
https://www.readbyqxmd.com/read/29027355/a-descriptive-analysis-of-rabies-post-exposure-prophylaxis-data-2013-ontario-canada
#11
D Middleton, J J Edwin, K O Johnson, B F Warshawsky
By 2013, the number of confirmed rabid animals in Ontario had decreased to unprecedented low numbers, yet the expected decrease in the number of courses of rabies post-exposure prophylaxis (RPEP) administered did not occur consistent with the decrease in animal rabies cases (Figure ). This prompted a review of the reasons that RPEP was administered in Ontario. This study provides a descriptive analysis of the exposure incidents resulting in RPEP administration in Ontario during 2013 using data obtained from the integrated Public Health Information System, a Web-based disease surveillance system...
October 13, 2017: Zoonoses and Public Health
https://www.readbyqxmd.com/read/29026929/the-outcome-of-proximal-fifth-metatarsal-fractures-redefining-treatment-strategies
#12
P Monteban, J van den Berg, J van Hees, S Nijs, H Hoekstra
BACKGROUND: To optimize the treatment strategy and reduce treatment costs of proximal fifth metatarsal fractures, clinical and patient-reported outcome, and its determinants were addressed. METHODS: A retrospective adult cohort study including 152 proximal fifth metatarsal fractures: 121 nonoperatively and 31 operatively treated. In the operative group, 21 were zone 1 and 10 zone 2 fractures. Median follow-up was 37.5 (IQR 20.8-52.3) months with a minimal follow-up of 6 months...
October 12, 2017: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/29026374/geophagy-as-risk-behaviour-for-gastrointestinal-nematode-infections-among-pregnant-women-attending-antenatal-clinics-in-a-humid-tropical-zone-of-nigeria
#13
Njoku Ivoke, Nnenna Ikpor, Obinna Ivoke, Felicia Ekeh, Ngozi Ezenwaji, Gregory Odo, Florence Iyaji, Uwakwe Onoja, Joseph Eyo
BACKGROUND: Geophagy is wide spread among pregnant women in Ebonyi State, Nigeria. OBJECTIVE: The aim of this study was to assess intestinal nematode infections among geophagous pregnant women in Southern Ebonyi State, Nigeria. METHODS: Pregnant women were aged 17-45 years at gestational ages of ≥ 14 to 24 weeks on hospital enrolment were sampled. Data on geophagy was collected using structured questionnaire. Gastrointestinal nematode status of the participants was determined by stool analyses...
March 2017: African Health Sciences
https://www.readbyqxmd.com/read/29024614/staphylococcus-aureus-infections-in-german-patients-with-type-2-diabetes-mellitus-after-orthopedic-surgery-incidence-risk-factors-and-clinical-and-health-economic-outcomes
#14
Fraence Gottschalk, Thomas Wilke, Sabrina Mueller, Kirstin Heinrich, Ulf Maywald, Andreas Fuchs, Holly Yu
BACKGROUND: This study assessed Staphylococcus aureus infection risk in patients with type 2 diabetes mellitus (T2DM) undergoing an orthopedic knee, hip, or spine surgery. PATIENTS AND METHODS: All patients with a diagnosis of T2DM in the period from 2010 to 2012 were identified from a German claims database. First inpatient knee, hip, or spine surgery was used as index date. Cumulative incidence of S. aureus infections was calculated for several time intervals...
October 12, 2017: Surgical Infections
https://www.readbyqxmd.com/read/29023928/evaluation-of-medical-and-dental-visits-in-new-york-city-opportunities-to-identify-persons-with-and-at-risk-for-diabetes-mellitus-in-dental-settings
#15
Noreen Myers-Wright, Ira B Lamster, John P Jasek, Shadi Chamany
OBJECTIVE: The identification of persons with or at risk for chronic diseases is a new practice paradigm for oral healthcare. Diabetes mellitus (DM) is a chronic disease of particular importance to oral health providers. This study sought to understand healthcare utilization patterns that would support the introduction of this new practice paradigm. METHODS: The primary and oral healthcare utilization patterns of New York City (NYC) adults were assessed using data collected from the 2013 NYC Community Health Survey...
October 11, 2017: Community Dentistry and Oral Epidemiology
https://www.readbyqxmd.com/read/29023855/hepatitis-c-virus-infection-in-jeddah-city-saudi-arabia-seroprevalence-and-knowledge
#16
Rajaa M Al-Raddadi, Noha A Dashash, Hani A Alghamdi, Zeyad M Al-Raddadi, Hanan S Alzahrani, Abdullah J Alsahafi, Abdullah M Algarni, Majed M Alghamdi, Raghad F Hakim, Abdulmohsen H Al-Zalabani, Fanar Hakim, Feras Ayman Moria
BACKGROUND: The infection rate of the hepatitis C virus (HCV) in Saudi Arabia is among the lowest in the world. However, it is likely that poor knowledge and awareness of HCV infection could minimize the effectiveness of prevention and control programs in the kingdom. OBJECTIVES: Thus, the study objective was to estimate the prevalence of HCV infection, and to assess current knowledge about it, in the targeted population. METHODS: Data on 5482 Saudi people attending primary healthcare centers in Jeddah City in 2014/2015 were analyzed in this cross-sectional study...
October 11, 2017: Journal of Medical Virology
https://www.readbyqxmd.com/read/29023582/presence-of-children-in-the-home-and-intimate-partner-violence-among-women-seeking-elective-pregnancy-termination
#17
Corinne Peek-Asa, Audrey F Saftlas, Anne B Wallis, Karisa Harland, Penny Dickey
INTRODUCTION: Growing evidence identifies adverse health effects for children who witness intimate partner violence at home. Research has also identified that women seeking elective pregnancy termination are at high risk for partner violence. However, little is known about the risk for violence exposure among the children of women seeking elective pregnancy termination. METHODS: We conducted a cross-sectional study of 957 women seeking elective pregnancy termination at a large family planning clinic...
2017: PloS One
https://www.readbyqxmd.com/read/29022529/deep-vein-thrombosis-in-the-era-of-high-hiv-and-tuberculosis-prevalence-a-prospective-review-of-its-diagnosis-and-treatment-in-a-quaternary-centre
#18
K E Hodkinson, J N Mahlangu
BACKGROUND: Venous thromboembolic disease (VTE) is a leading cause of morbidity and mortality worldwide. HIV and tuberculosis (TB) infections have an aetiological association with VTE. Implementation of national HIV and TB programmes in South Africa (SA) has changed the burden of these two conditions, with resultant effects on VTE prevalence. Furthermore, with the increased use of direct oral anticoagulants (DOACs), baseline thrombosis data are needed to evaluate the effect of these new agents...
September 22, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/29020681/the-socioeconomic-burden-of-obesity
#19
Jakob Kjellberg, Arendse Tange Larsen, Rikke Ibsen, Betina Højgaard
OBJECTIVE: To evaluate the socioeconomic impact of obesity by estimating the direct and indirect costs associated with obesity in Denmark, based on individual level data. METHODS: Costs were assessed for different BMI groups, and the relative risks for change in direct and indirect costs per BMI point above 30 were estimated. A fourth analysis estimated the odds ratio for comorbidities per BMI point above 30. Individual data on income, social transfer payments, healthcare costs and diagnoses were retrieved from national registries...
October 12, 2017: Obesity Facts
https://www.readbyqxmd.com/read/29020308/management-of-latent-tuberculosis-infection-among-healthcare-workers-10-year-experience-at-a-single-center
#20
Esther Arguello Perez, Susan K Seo, William J Schneider, Cynthia Eisenstein, Arthur E Brown
Background: The risk of infection with Mycobacterium tuberculosis among healthcare workers (HCWs) is estimated to be higher than the general population. However, HCW acceptance and compliance with available latent tuberculosis infection (LTBI) treatment regimens has been problematic. Recently, regimens have become available that might improve HCW acceptance and compliance with LTBI treatment. Methods: A retrospective single-center review of Employee Health &Wellness Services records of all HCWs diagnosed with LTBI was conducted...
August 17, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
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