Robine Janssen, Laura Benito-Zarza, Pim Cleijpool, Marta G Valverde, Silvia M Mihăilă, Shanna Bastiaan-Net, Johan Garssen, Linette E M Willemsen, Rosalinde Masereeuw
Ever since the implementation of microfluidics in the biomedical field, in vitro models have experienced unprecedented progress that has led to a new generation of highly complex miniaturized cell culture platforms, known as Organs-on-a-Chip (OoC). These devices aim to emulate biologically relevant environments, encompassing perfusion and other mechanical and/or biochemical stimuli, to recapitulate key physiological events. While OoCs excel in simulating diverse organ functions, the integration of the immune organs and immune cells, though recent and challenging, is pivotal for more comprehensive representation of human physiology...
April 16, 2024: Advanced Healthcare Materials