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Healthcare predictive modeling

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https://www.readbyqxmd.com/read/28541449/barriers-to-alcohol-screening-among-hypertensive-patients-and-the-role-of-stigma-lessons-for-the-implementation-of-screening-and-brief-interventions-in-european-primary-care-settings
#1
Franz Hanschmidt, Jakob Manthey, Ludwig Kraus, Emanuele Scafato, Antoni Gual, Carsten Grimm, Jürgen Rehm
Aims: 1. To quantify barriers to alcohol screening among hypertensive patients reported by primary healthcare professionals. 2. To examine whether education and screening frequency measures are associated with stigma-related barriers. Methods: A web survey was conducted among 3081 primary healthcare professionals from France, Germany, Italy, Spain and the UK. Participants were asked about perceived barriers to alcohol screening as free-text response. The replies were independently categorized by two raters...
May 25, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28531987/electrospinning-of-thermoplastic-carboxymethyl-cellulose-poly-ethylene-oxide-nanofibers-for-use-in-drug-release-systems
#2
Akbar Esmaeili, Mahsa Haseli
Polymeric delivery systems using electrospun nanofibers have been developed for many applications, notably for drug delivery and tissue engineering in the healthcare industry. In this study, a nanofiber drug carrier was fabricated via two different electrospinning processes, blend and coaxial, using a new degradable thermoplastic carboxymethyl cellulose (TCMC) and poly(ethylene oxide) (PEO). The TCMC was synthesized by graft copolymerization with methyl acrylate. Tetracycline hydrochloride served as a drug model incorporated within these nanofibers and their performance as a drug-carrier scaffold was evaluated...
August 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28531380/are-traditional-body-fat-equations-and-anthropometry-valid-to-estimate-body-fat-in-children-and-adolescents-living-with-hiv
#3
Luiz Rodrigo Augustemak de Lima, Priscila Custódio Martins, Carlos Alencar Souza Alves Junior, João Antônio Chula de Castro, Diego Augusto Santos Silva, Edio Luiz Petroski
The aim of this study was to assess the validity of traditional anthropometric equations and to develop predictive equations of total body and trunk fat for children and adolescents living with HIV based on anthropometric measurements. Forty-eight children and adolescents of both sexes (24 boys) aged 7-17 years, living in Santa Catarina, Brazil, participated in the study. Dual-energy X-ray absorptiometry was used as the reference method to evaluate total body and trunk fat. Height, body weight, circumferences and triceps, subscapular, abdominal and calf skinfolds were measured...
May 19, 2017: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28528557/-naming-and-framing-the-impact-of-labeling-on-health-state-values-for-multiple-sclerosis
#4
Colin Green, Elizabeth Goodwin, Annie Hawton
INTRODUCTION: Health state valuation is a key input in many economic evaluations that inform resource allocation across competing healthcare interventions. Empirical evidence has shown that, in preference elicitation surveys, respondents may value a health state differently if they are aware of the condition causing it ('labeling effects'). This study investigates the impact of including a multiple sclerosis (MS) label for valuation of MS health states. METHODS: Health state values for MS were elicited using two internet-based surveys in representative samples of the UK population ( n = 1702; n = 1788)...
May 1, 2017: Medical Decision Making: An International Journal of the Society for Medical Decision Making
https://www.readbyqxmd.com/read/28522924/use-of-the-4kscore-test-to-predict-the-risk-of-aggressive-prostate-cancer-prior-to-prostate-biopsy-overall-cost-savings-and-improved-quality-of-care-to-the-us-healthcare-system
#5
Jeffrey D Voigt, Yan Dong, Vincent Linder, Stephen Zappala
The 4Kscore® Test (BioReference Laboratories, Elmwood Park, NJ) is a blood test that accurately determines the risk of aggressive prostate cancer and significantly reduces prostate biopsies and associated overdiagnosis and overtreatment of indolent cancer. A budget impact model was developed to test the hypothesis that the 4Kscore Test can improve quality of care and deliver cost savings for patients who are suspected of having prostate cancer and would otherwise undergo prostate biopsy under the current standard of care (SOC) in the United States...
2017: Reviews in Urology
https://www.readbyqxmd.com/read/28515200/impact-of-expedited-partner-therapy-ept-implementation-on-chlamydia-incidence-in-the-usa
#6
Okeoma Mmeje, Sarah Wallett, Giselle Kolenic, Jason Bell
OBJECTIVES: The diagnosis and treatment of Chlamydia trachomatis infection is important in preventing persistent or recurrent infection. Expedited partner therapy (EPT) is the favoured and supported method for STI treatment of the Centers for Disease Control and Prevention when the provider cannot be assured that all recent sexual partner(s) will seek therapy. EPT is legally permissible in 38 states and is endorsed by healthcare organisations to decrease the rates of chlamydia and gonorrhoea infection...
May 17, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28515183/modeling-lifetime-costs-and-health-outcomes-attributable-to-secondhand-smoke-exposure-at-home-among-korean-adult-women
#7
Jiyae Lee, Ah Ram Han, Dalwoong Choi, Kyung-Min Lim, SeungJin Bae
PURPOSE: The aim of this research is to estimate lifetime costs and health consequences for Korean adult women who were exposed to secondhand smoke (SHS) at home. METHODS: A Markov model was developed to project the lifetime healthcare costs and health outcomes of a hypothetical cohort of Korean women who are 40 years old and were married to current smokers. The Korean epidemiological data were used to reflect the natural history of SHS-exposed and non-exposed women...
May 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28508814/plausibility-of-individual-decisions-from-random-forests-in-clinical-predictive-modelling-applications
#8
Dieter Hayn, Harald Walch, Jörg Stieg, Karl Kreiner, Hubert Ebner, Günter Schreier
BACKGROUND: Machine learning algorithms are a promising approach to help physicians to deal with the ever increasing amount of data collected in healthcare each day. However, interpretation of suggestions derived from predictive models can be difficult. OBJECTIVES: The aim of this work was to quantify the influence of a specific feature on an individual decision proposed by a random forest (RF). METHODS: For each decision tree within the RF, the influence of each feature on a specific decision (FID) was quantified...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28504931/robust-real-time-musculoskeletal-modeling-driven-by-electromyograms
#9
Guillaume Durandau, Dario Farina, Massimo Sartori
OBJECTIVE: Current clinical biomechanics involves lengthy data acquisition and time-consuming offline analyses and current biomechanical models cannot be used for real-time control in man-machine interfaces. We developed a method that enables online analysis of neuromusculoskeletal function in vivo in the intact human. METHODS: We used electromyography (EMG)-driven musculoskeletal modeling to simulate all transformations from muscle excitation onset (EMGs) to mechanical moment production around multiple lower-limb degrees of freedom (DOFs)...
May 12, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28501464/the-connection-between-nursing-diagnosis-and-the-use-of-healthcare-resources
#10
María Consuelo Company-Sancho, Marcos Estupiñán-Ramírez, Hilda Sánchez-Janáriz, Rita Tristancho-Ajamil
AIM: The health service invests up to 75% of its resources on chronic care where the focus should be on caring rather than curing. Nursing staff focuses their work on such care. Care requires being redorded in health histories through the standardized languages. These records enable useful analyses to organisational and healthcare decision-making. Our proposal is to know the association of between nursing diagnosis and a higher total expenditure on health. METHOD: An observational cross-sectional analytical study was performed based on data from electronic health records in Primary Care (Drago-AP), hospital discharges (CMBD-AH) and prescriptions (REC-SCS) of patients over 50 from 2012-2013 in the Canary Islands...
May 10, 2017: Enfermería Clínica
https://www.readbyqxmd.com/read/28498196/identifying-increased-risk-of-readmission-and-in-hospital-mortality-using-hospital-administrative-data-the-ahrq-elixhauser-comorbidity-index
#11
Brian J Moore, Susan White, Raynard Washington, Natalia Coenen, Anne Elixhauser
OBJECTIVE: We extend the literature on comorbidity measurement by developing 2 indices, based on the Elixhauser Comorbidity measures, designed to predict 2 frequently reported health outcomes: in-hospital mortality and 30-day readmission in administrative data. The Elixhauser measures are commonly used in research as an adjustment factor to control for severity of illness. DATA SOURCES: We used a large analysis file built from all-payer hospital administrative data in the Healthcare Cost and Utilization Project State Inpatient Databases from 18 states in 2011 and 2012...
May 11, 2017: Medical Care
https://www.readbyqxmd.com/read/28498094/predictors-of-all-cause-30-day-readmission-among-medicare-patients-with-type-2-diabetes
#12
Jenna Collins, Ibrahim M Abbass, Raymond Harvey, Brandon Suehs, Claudia Uribe, Jonathan Bouchard, Todd Prewitt, Tony DeLuzio, Elsie Allen
OBJECTIVE: Readmission is costly among patients with type 2 diabetes (T2DM) in Medicare Advantage Prescription Drug Plans; identifying high-risk patients is necessary for targeting reduction programs. The objective of this study was to develop a claims-based algorithm to predict all-cause 30-day readmission among patients with T2DM. METHODS: This study used administrative data from 1/1/2012 through 1/31/2014. The cohort included hospitalized T2DM patients, aged 18-90 with ≥12 months' continuous-enrollment before an unplanned hospital admission and ≥1 month of enrollment post-discharge, excluding patients in long-term care >30 days pre-index...
May 12, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28498024/a-prospective-risk-assessment-of-informal-carers-medication-administration-errors-within-the-domiciliary-setting
#13
Anam Parand, Giuliana Faiella, Bryony Dean Franklin, Maximilian Johnston, Fabrizio Clemente, Neville A Stanton, Nick Sevdalis
Increasingly, medication is being administered at home by family and friends of the care-recipient. This study aims to identify and analyse risks associated with potential drug administration errors made by informal carers at home. We mapped medication administration at home with a multidisciplinary team that included carers, healthcare professionals and patients. Evidence-based risk-analysis methodologies were applied: Healthcare Failure Modes and Effect Analysis (HFMEA), Systematic Human Error Reduction and Prediction Analysis (SHERPA) and Systems-Theoretic Accident Model and Processes (STAMP)...
May 12, 2017: Ergonomics
https://www.readbyqxmd.com/read/28495348/development-of-a-tripolar-model-of-technology-acceptance-hospital-based-physicians-perspective-on-ehr
#14
Mher Beglaryan, Varduhi Petrosyan, Edward Bunker
BACKGROUND AND PURPOSE: In health care, information technologies (IT) hold a promise to harness an ever-increasing flow of health related information and bring significant benefits including improved quality of care, efficiency, and cost containment. One of the main tools for collecting and utilizing health data is the Electronic Health Record (EHR). EHRs implementation can face numerous barriers to acceptance including attitudes and perceptions of potential users, required effort attributed to their implementation and usage, and resistance to change...
June 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/28490271/validation-of-a-cardiovascular-disease-policy-micro-simulation-model-using-both-survival-and-receiver-operating-characteristic-curves
#15
Ankur Pandya, Stephen Sy, Sylvia Cho, Sartaj Alam, Milton C Weinstein, Thomas A Gaziano
BACKGROUND: Despite some advances, cardiovascular disease (CVD) remains the leading cause of death and healthcare costs in the United States. We therefore developed a comprehensive CVD policy simulation model that identifies cost-effective approaches for reducing CVD burden. This paper aims to: 1) describe our model in detail; and 2) perform model validation analyses. METHODS: The model simulates 1,000,000 adults (ages 35 to 80 years) using a variety of CVD-related epidemiological data, including previously calibrated Framingham-based risk scores for coronary heart disease and stroke...
May 1, 2017: Medical Decision Making: An International Journal of the Society for Medical Decision Making
https://www.readbyqxmd.com/read/28489730/improved-hiv-1-viral-load-monitoring-capacity-using-pooled-testing-with-marker-assisted-deconvolution
#16
Tao Liu, Joseph W Hogan, Michael J Daniels, Mia Coetzer, Yizhen Xu, Gerald Bove, Allison K Delong, Lauren Ledingham, Millicent Orido, Lameck Diero, Rami Kantor
OBJECTIVE: Improve pooled viral load (VL) testing to increase HIV treatment monitoring capacity, particularly relevant for resource-limited settings. DESIGN: We developed mMPA (marker-assisted mini-pooling with algorithm), a new VL pooling deconvolution strategy that utilizes information from low-cost, routinely-collected clinical markers to determine an efficient order of sequential individual VL testing and dictates when the sequential testing can be stopped. METHODS: We simulated the use of pooled testing to ascertain virological failure status on 918 participants from three studies conducted at the Academic Model Providing Access to Healthcare (AMPATH) in Eldoret, Kenya, and estimated the number of assays needed when using mMPA and other pooling methods...
April 25, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28486388/effect-of-beta-blockers-on-mortality-after-open-repair-of-abdominal-aortic-aneurysm
#17
Husain N Alshaikh, Joseph K Canner, Mahmoud Malas
OBJECTIVE: To assess the effect of perioperative beta blocker (BB) use on postoperative in-hospital mortality after open repair of abdominal aortic aneurysm (OAR). BACKGROUND: Postoperative mortality after OAR ranges from 3.0% to 4.5%. Insight about the effect of BBs on postoperative mortality after OAR is currently lacking. METHODS: This is a retrospective study of patients undergoing OAR from 2009-Q3 to 2015-Q1 in the Premier Healthcare Database...
May 8, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28481991/deep-learning-for-healthcare-review-opportunities-and-challenges
#18
Riccardo Miotto, Fei Wang, Shuang Wang, Xiaoqian Jiang, Joel T Dudley
Gaining knowledge and actionable insights from complex, high-dimensional and heterogeneous biomedical data remains a key challenge in transforming health care. Various types of data have been emerging in modern biomedical research, including electronic health records, imaging, -omics, sensor data and text, which are complex, heterogeneous, poorly annotated and generally unstructured. Traditional data mining and statistical learning approaches typically need to first perform feature engineering to obtain effective and more robust features from those data, and then build prediction or clustering models on top of them...
May 6, 2017: Briefings in Bioinformatics
https://www.readbyqxmd.com/read/28481168/reorganisation-of-healthcare-services-for-children-and-families-improving-collaboration-service-quality-and-worker-well-being
#19
Monica Martinussen, Sabine Kaiser, Frode Adolfsen, Joshua Patras, Astrid M Richardsen
This study is an evaluation of a reorganisation of different services for children and their families in a Norwegian municipality. The main aim of the reorganisation was to improve interprofessional collaboration through integrating different social services for children and their parents. The evaluation was guided by the Job Demands-Resources Model with a focus on social and healthcare workers' experiences of their work, including job demands and resources, service quality, and well-being at work. The survey of the employees was conducted at three measurement points: before (T1) and after (T2, T3) the reorganisation took place, and included between 87 and 122 employees...
May 8, 2017: Journal of Interprofessional Care
https://www.readbyqxmd.com/read/28480236/serial-procalcitonin-as-a-predictor-of-bacteremia-and-need-for-intensive-care-unit-care-in-adults-with-pneumonia-including-those-with-highest-severity-a-prospective-cohort-study
#20
Suzanne M McCluskey, Philipp Schuetz, Michael S Abers, Benjamin Bearnot, Maria E Morales, Debora Hoffman, Shreya Patel, Lauren Rosario, Victor Chiappa, Blair A Parry, Ryan T Callahan, Sheila A Bond, Kent Lewandrowski, William Binder, Michael R Filbin, Jatin M Vyas, Michael K Mansour
BACKGROUND: Procalcitonin (PCT) is a prohormone that rises in bacterial pneumonia and has promise in reducing antibiotic use. Despite these attributes, there are inconclusive data on its use for clinical prognostication. We hypothesize that serial PCT measurements can predict mortality, intensive care unit (ICU) admission, and bacteremia. METHODS: A prospective cohort study of inpatients diagnosed with pneumonia was performed at a large tertiary care center in Boston, Massachusetts...
2017: Open Forum Infectious Diseases
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