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https://www.readbyqxmd.com/read/28240008/role-of-plasticity-region-genes-and-cage-gene-of-cagpai-of-helicobacter-pylori-in-development-of-gastrointestinal-gi-diseases
#1
Shokufe GholizadeTobnagh, Seyedeh Zahra Bakhti, Saeid Latifi Navid, Saber Zahri, Fatemeh Sadat Bakhti
Background: Helicobacter pylori is a Gram-negative, micro aerophilic bacterium in the human stomach that is associated with the development of gastrointestinal ailments such as peptic ulcer (PU) and gastric cancer (GC). In the present study, plasticity region genes (jhp0940, jhp0945 and jhp0947) and and cagE gene of cagPAI were assessed independently and in combination for their ability to predict clinical consequences. Materials and Methods: A total of 211 strains which were isolated from patients with different gastrointestinal diseases (114 with non-atrophic gastritis, 59 with PU, and 38 with GC) were genotyped by PCR and sequencing...
1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28239958/differential-sex-effects-of-systolic-blood-pressure-and-ldl-c-on-type-2-diabetes-life-course-data-from-the-bogalusa-heart-study
#2
Benjamin D Pollock, Wei Chen, Emily W Harville, Tian Shu, Vivian Fonseca, Franck Mauvais-Jarvis, Tanika N Kelly, Lydia A Bazzano
BACKGROUND: There may be sex-specific cardiometabolic mechanisms early in life that affect the development of type 2 diabetes (T2DM) through mid-adulthood. Yet, there have been few studies examining whether early life-course interactions between cardiometabolic risk factors and sex are associated with incident T2DM. METHODS: We followed n = 7,725 children from the Bogalusa Heart Study through mid-adulthood to examine whether low-density lipoprotein-cholesterol (LDL-C), high-density lipoprotein-cholesterol (HDL-C), body mass index (BMI), or systolic blood pressure (SBP) differentially impact the risk of T2DM for females versus males...
February 27, 2017: Journal of Diabetes
https://www.readbyqxmd.com/read/28239857/neospora-caninum-in-beef-herds-in-new-south-wales-australia-1-seroprevalence-study
#3
B J Moloney, P D Kirkland, C Heuer
OBJECTIVE: To determine the seroprevalence of Neospora caninum antibodies in beef breeding herds across New South Wales (NSW) and to determine if there are any differences associated with geographic location and other herd-level factors. METHODS: Cross-sectional survey of beef breeding cows (n = 3298) from 63 properties (approximately 55 cows per herd) sampled randomly from six regions in NSW using a multistage survey design. Samples were tested by ELISA for N...
March 2017: Australian Veterinary Journal
https://www.readbyqxmd.com/read/28239800/intermediate-cd14-cd16-monocyte-predicts-severe-coronary-stenosis-and-extensive-plaque-involvement-in-asymptomatic-individuals
#4
Shyh-Chyi Lo, Wen-Jeng Lee, Ching-Yi Chen, Bai-Chin Lee
Circulating leukocyte subtypes and monocyte subsets are independent predictors of cardiovascular events. We hypothesized that an increased leukocyte subtype would predict severe coronary stenosis and extensive plaque involvement. We retrospectively analyzed clinical, laboratory, and coronary CT data in a total of 588 asymptomatic adults (69% men; mean age, 57 ± 9 years) undergoing a general health check-up. Intermediate CD14(++)CD16(+) monocyte count had the strongest association with mixed and calcified plaque scores, whereas the numbers of neutrophils and classical CD14(++)CD16(-) monocytes were significantly associated with non-calcified plaque score...
February 26, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28239560/risk-factors-for-hearing-impairment-among-adults-with-diabetes-the-hispanic-community-health-study-study-of-latinos-hchs-sol
#5
Kathleen E Bainbridge, Catherine C Cowie, Franklyn Gonzalez, Howard J Hoffman, Elizabeth Dinces, Jeremiah Stamler, Karen J Cruickshanks
AIM: The aim was to examine risk factors for hearing impairment among Hispanic/Latino adults with diabetes. METHODS: Findings are based on 3384 participants aged 18-76 years with diagnosed or previously undetected diabetes who completed audiometric testing as part of the Hispanic Community Health Study/Study of Latinos. We defined hearing impairment as the pure-tone average (PTA) >25 decibels hearing level [dB HL] of pure-tone thresholds at high frequencies (3000, 4000, 6000, and 8000 Hz) in the worse ear and defined a second hearing impairment outcome with the additional requirement of PTA >25 dB HL of low/mid-frequency (500, 1000, and 2000 Hz) thresholds in the worse ear...
December 2016: Journal of Clinical & Translational Endocrinology
https://www.readbyqxmd.com/read/28239217/sibling-relationship-quality-and-mexican-origin-adolescents-and-young-adults-familism-values-and-adjustment
#6
Sarah E Killoren, Sue A Rodríguez De Jesús, Kimberly A Updegraff, Lorey A Wheeler
We examined profiles of sibling relationship qualities in 246 Mexican-origin families living in the United States using latent profile analyses. Three profiles were identified: Positive, Negative and Affect-Intense. Links between profiles and youths' familism values and adjustment were assessed using longitudinal data. Siblings in the Positive profile reported the highest familism values, followed by siblings in the Affect-Intense profile and, finally, siblings in the Negative profile. Older siblings in the Positive and Affect-Intense profiles reported fewer depressive symptoms than siblings in the Negative profile...
March 2017: International Journal of Behavioral Development
https://www.readbyqxmd.com/read/28238953/cost-effectiveness-of-screening-patients-with-gastroesophageal-reflux-disease-for-barrett-s-esophagus-with-a-minimally-invasive-cell-sampling-device
#7
Curtis R Heberle, Amir-Houshang Omidvari, Ayman Ali, Sonja Kroep, Chung Yin Kong, John M Inadomi, Joel H Rubenstein, Angela C Tramontano, Emily C Dowling, William D Hazelton, E Georg Luebeck, Iris Lansdorp-Vogelaar, Chin Hur
BACKGROUND & AIMS: It is important to identify patients with Barrett's esophagus (BE), the precursor to esophageal adenocarcinoma (EAC). Patients with BE are usually identified by endoscopy, which is expensive. The cytosponge, which collects tissue from the esophagus non-invasively, could be a cost-effective tool for screening individuals with gastroesophageal reflux disease (GERD), who are at increased risk for BE. We developed a model to analyze the cost effectiveness of using cytosponge in first-line screening of patients with GERD for BE with endoscopic confirmation, compared to endoscopy screening only, METHODS: We incorporated data from a large clinical trial of cytosponge performance into 2 validated microsimulation models of EAC progression (the esophageal adenocarcinoma model from the Massachusetts General Hospital and the microsimulation screening analysis model from Erasmus University Medical Center)...
February 23, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28238924/post-operative-infections-are-associated-with-increased-risk-of-cardiac-events-in-vascular-patients
#8
Tristen T Chun, Manuel Garcia-Toca, James F Eng, Jeffrey Slaiby, Edward J Marcaccio, William G Cioffi, Daithi S Heffernan
OBJECTIVE: Despite advances in peri-operative care, the rate of cardiac events in vascular patients remains high. We have previously shown that infections in trauma patients are associated with higher rates of subsequent cardiac complications, likely due to the additive effect of a second hit of an infection following the trauma. The aim of this study was to investigate whether there is an association between post-operative infections and subsequent cardiac events in vascular patients...
February 23, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28238730/disability-and-health-outcomes-in-geospatial-analyses-of-southeastern-u-s-county-health-data
#9
David W Hollar
BACKGROUND: People with disabilities tend to be at risk for secondary conditions. There is a need for comprehensive disability and health databases, including geographic information systems to evaluate trends in health, functioning, and employment. OBJECTIVE: We evaluated county levels in morbidity and mortality across the Southeastern United States using spatial regression, examining 2015 trends in accordance with Healthy People 2020 objectives. METHODS: We merged 2015 National County Health Rankings and the 2015 Social Security Administration's Report on SSDI Beneficiaries, all for n = 1387 Southeastern U...
February 16, 2017: Disability and Health Journal
https://www.readbyqxmd.com/read/28238696/upper-body-subcutaneous-fat-is-associated-with-cardiometabolic-risk-factors
#10
Jane J Lee, Alison Pedley, Kate E Therkelsen, Udo Hoffmann, Joseph M Massaro, Daniel Levy, Michelle T Long
BACKGROUND: Upper body subcutaneous fat is a distinct fat depot that may confer increased cardiometabolic risk. We examined the cross-sectional associations between upper body subcutaneous fat volume and cardiometabolic risk factors. METHODS: Participants were from the Framingham Heart Study who underwent multi-detector computed tomography between 2008-2011. Sex-specific multivariable-adjusted regression analyses were conducted. Covariates included age, ethnicity, smoking status, alcohol intake, postmenopausal status, and hormone replacement therapy...
February 24, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28238694/interaction-of-physical-activity-and-body-mass-index-on-mortality-in-coronary-heart-disease-data-from-the-nord-tr%C3%A3-ndelag-health-study
#11
Trine Moholdt, Carl J Lavie, Javaid Nauman
AIMS: The role of physical activity in the BMI-survival relationship in coronary heart disease is unclear. Our aim was to examine isolated and combined associations between BMI and physical activity, and mortality in subjects with coronary heart disease.. METHODS AND RESULTS: 6 493 participants (34.4% women) with coronary heart disease from the Nord-Trøndelag Health Study, with examinations in 1986, 1996, and 2007, were followed until the end of 2014. We calculated hazard ratios (HR) for all-cause and cardiovascular disease mortality, estimated using Cox proportionate hazard regression adjusted for age, smoking, diabetes, hypertension, self-reported health status, and alcohol...
February 23, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28238691/early-invasive-versus-initial-conservative-strategies-for-women-with-non-st-elevation-acute-coronary-syndromes-propensity-matched-analysis
#12
Islam Y Elgendy, Ahmed N Mahmoud, Hend Mansoor, Anthony A Bavry
BACKGROUND: Studies conducted largely in men have shown improved outcomes with an early invasive strategy with non-ST-elevation acute coronary syndrome. In contrast, data have been less conclusive in women, with some trials demonstrating potential harm. This study aims to assess if an early invasive strategy in women is associated with better outcomes in real world data. METHODS: Women admitted with a primary diagnosis of non-ST-elevation myocardial infarction or unstable angina were identified from the National Inpatient Sample years 2012-2013...
February 24, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28238682/association-between-dietary-pattern-and-cardiometabolic-risk-in-children-and-adolescents-a-systematic-review
#13
REVIEW
Naruna Pereira Rocha, Luana Cupertino Milagres, Giana Zarbato Longo, Andréia Queiroz Ribeiro, Juliana Farias de Novaes
OBJECTIVE: To evaluate the association between dietary patterns and cardiometabolic risk factors in children and adolescents. DATA SOURCE: This article followed the recommendations of PRISMA, which aims to guide review publications in the health area. The article search strategy included searches in the electronic databases MEDLINE via PubMed, Scopus, and LILACS. There was no date limitation for publications. The descriptors were used in English according to MeSH and in Portuguese according to DeCS...
February 23, 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/28238673/bisphosphonate-use-after-hip-fracture-in-older-adults-a%C3%A2-nationwide-retrospective-cohort-study
#14
Peter Nordström, Annika Toots, Yngve Gustafson, Karl-Göran Thorngren, Ami Hommel, Anna Nordström
OBJECTIVES: The aim of this study was to investigate the association between bisphosphonate use and the risk of new fracture in a nationwide cohort of individuals with previous hip fractures, with emphasis on individuals above 80 years of age. DESIGN, SETTING, AND PARTICIPANTS: From a nationwide cohort with hip fracture (2006-2012) (n = 93, 601), each individual prescribed bisphosphonates after hip fracture (n = 5845) was matched with up to three individuals not prescribed bisphosphonates, resulting in a cohort of 21,363 individuals...
February 23, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28238670/association-of-pregnancy-with-stone-formation-among-us-women-a-national-health-and-nutrition-examination-survey-analysis-2007-2012
#15
Lael Reinstatler, Sari Khaleel, Vernon M Pais
PURPOSE: Lithogenic urinary changes occur during pregnancy. Such changes may increase stone proclivity in working and child rearing aged women thereafter. However, such an association has not been previously identified. MATERIALS AND METHODS: We analyzed nationally representative data from 2007-2012 National Health and Nutrition Examination Survey to assess the association between pregnancy and nephrolithiasis. RESULTS: The weighted national prevalence of nephrolithiasis among women ≤50 was 6...
February 23, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28238617/interaction-between-vitamin-d-and-lipoprotein-a-on-the-presence-and-extent-of-coronary-heart-disease
#16
Kuibao Li, Xiyan Yang, Lefeng Wang, Mulei Chen, Li Xu, Xinchun Yang
BACKGROUND: Given both lipoprotein (Lp)(a) and vitamin D have been found to be associated with coronary heart disease (CHD) risk and a biochemical link between vitamin D and cholesterol on atherosclerosis has been proposed, we hypothesised there could exist an interaction between Lp(a) and vitamin D on the severity of CHD. METHODS: Lp(a) and 25-OH vitamin D were measured in the plasma of 348 consecutive patients (mean age 62.4±10.5 years; 56.3% male) undergoing coronary angiography at our Heart Center...
February 6, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28238501/is-tachycardia-at-discharge-from-the-pediatric-emergency-department-a-cause-for-concern-a%C3%A2-nonconcurrent-cohort-study
#17
Paria M Wilson, Todd A Florin, Guixia Huang, Matthew Fenchel, Matthew R Mittiga
STUDY OBJECTIVE: We evaluate the association between discharge tachycardia and (1) emergency department (ED) and urgent care revisit and (2) receipt of clinically important intervention at the revisit. METHODS: The study included a nonconcurrent cohort of children aged 0 to younger than 19 years, discharged from 2 pediatric EDs and 4 pediatric urgent care centers in 2013. The primary exposure was discharge tachycardia (last recorded pulse rate ≥99th percentile for age)...
February 23, 2017: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/28238496/prevalence-of-polycystic-ovary-syndrome-in-chinese-obese-women-of-reproductive-age-with-or-without-metabolic-syndrome
#18
Peiwen Liang, Liuqing Xi, Juan Shi, Wanyu Li, Shaoqian Zhao, Yuying Deng, Rui Wang, Yingkai Sun, Bin Gu, Lihui Yuan, Yifei Zhang, Weiqiong Gu, Weiqing Wang, Jie Hong
OBJECTIVE: To compare the prevalence of polycystic ovary syndrome (PCOS) and related clinical characteristics between metabolically unhealthy obese (MUO) and metabolically healthy obese (MHO) women of reproductive age. DESIGN: Cross-sectional clinical study. SETTING: Tertiary hospital. PATIENT(S): We studied 299 MUO and 122 MHO Chinese women matched on body mass index. Metabolically healthy obese was defined as obesity with no more than one metabolic abnormality...
February 23, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28238433/impact-of-temperature-variation-on-mortality-an-observational-study-from-12-counties-across-hubei-province-in-china
#19
Yunquan Zhang, Chuanhua Yu, Junzhe Bao, Xudong Li
BACKGROUND: Compared with cold- and heat-related health impacts, the evidence was very limited in assessing the mortality effects of temperature variation (TV) accounting for both intra-day and inter-day changes in temperature. OBJECTIVE: We used a newly proposed composite indicator of intra-day and inter-day TV and evaluated TV-mortality associations in Hubei, China at the provincial level. METHODS: Daily mortality and meteorological data during 2009-2012 were obtained from 12 urban and rural counties across Hubei Province in China...
February 23, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28238345/anastomotic-leak-after-colorectal-resection-a-population-based-study-of-risk-factors-and-hospital-variation
#20
Vahagn C Nikolian, Neil S Kamdar, Scott E Regenbogen, Arden M Morris, John C Byrn, Pasithorn A Suwanabol, Darrell A Campbell, Samantha Hendren
BACKGROUND: Anastomotic leak is a major source of morbidity in colorectal operations and has become an area of interest in performance metrics. It is unclear whether anastomotic leak is associated primarily with surgeons' technical performance or explained better by patient characteristics and institutional factors. We sought to establish if anastomotic leak could serve as a valid quality metric in colorectal operations by evaluating provider variation after adjusting for patient factors...
February 18, 2017: Surgery
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