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https://www.readbyqxmd.com/read/27923114/effect-of-bystander-cpr-initiation-prior-to-the-emergency-call-on-rosc-and-30day-survival-an-evaluation-of-548-emergency-calls
#1
Søren Viereck, Thea Palsgaard Møller, Annette Kjær Ersbøll, Fredrik Folke, Freddy Lippert
BACKGROUND: This study aimed at evaluating if time for initiation of bystander cardiopulmonary resuscitation (CPR) - prior to the emergency call (CPRprior) versus during the emergency call following dispatcher-assisted CPR (CPRduring) - was associated with return of spontaneous circulation (ROSC) and 30-day survival. The secondary aim was to identify predictors of CPRprior. METHODS: This observational study evaluated out-of-hospital cardiac arrests (OHCA) occurring in the Capital Region of Denmark from 01...
December 3, 2016: Resuscitation
https://www.readbyqxmd.com/read/27921197/counselees-perspectives-of-genomic-counseling-following-online-receipt-of-multiple-actionable-complex-disease-and-pharmacogenomic-results-a-qualitative-research-study
#2
Kevin Sweet, Shelly Hovick, Amy C Sturm, Tara Schmidlen, Erynn Gordon, Barbara Bernhardt, Lisa Wawak, Karen Wernke, Joseph McElroy, Laura Scheinfeldt, Amanda E Toland, J S Roberts, Michael Christman
Genomic applications raise multiple challenges including the optimization of genomic counseling (GC) services as part of the results delivery process. More information on patients' motivations, preferences, and informational needs are essential to guide the development of new, more efficient practice delivery models that capitalize on the existing strengths of a limited genetic counseling workforce. Semi-structured telephone interviews were conducted with a subset of counselees from the Coriell Personalized Medicine Collaborative following online receipt of multiple personalized genomic test reports...
December 5, 2016: Journal of Genetic Counseling
https://www.readbyqxmd.com/read/27921130/-does-the-certification-according-to-endocert-lead-to-a%C3%A2-better-quality-of-treatment
#3
P Weber, A C Paulus, D Hallmen, A Steinbrück, F Schmidutz, V Jansson
BACKGROUND: Certification according to EndoCert in the field of arthroplasty in Germany aims at standardization of treatment and with this optimization of its quality. However, huge capital investment and efforts are necessary. There are currently more than 400 certified centres in Germany. Our Department of Orthopaedics at a German medical school was certified in the pilot phase. The aim of this study was to analyse whether there was a difference in the quality in the year after the certification...
December 5, 2016: Der Orthopäde
https://www.readbyqxmd.com/read/27921014/fireworks-related-injuries-in-iran-a-survey-following-the-2014-new-year-s-festival-in-tabriz
#4
Samad Shams Vahdati, Jamil Hemmate Gadim, Hossein Mazouchian
BACKGROUND: Iranian people celebrate the last Wednesday eve of the year as Chaharshanbe Suri and use explosives and firecrackers as part of this festival. OBJECTIVES: This study concerned fireworks injuries related to the Chaharshanbe Suri festival in Tabriz, a provincial capital in East Azerbaijan, Iran, to evaluate the epidemiology and provide data to prevent and manage these accidents. PATIENTS AND METHODS: This study was comprised of patients who were treated at the emergency department of Tabriz Sina hospital with burn injuries related to fireworks...
July 2016: Trauma Monthly
https://www.readbyqxmd.com/read/27920615/spinal-health-the-backbone-of-chiropractic-s-identity
#5
Richard A Brown
OBJECTIVES: The purpose of this commentary is to explore the concepts underpinning professional identity, assess their relevance to chiropractic, and propose a model by which a strong identity for the chiropractic profession may be achieved. DISCUSSION: The professional identity of chiropractic has been a constant source of controversy throughout its history. Attempts to establish a professional identity have been met with resistance from internal factions divided over linguistics, philosophy, technique, and chiropractic's place in the health care framework...
December 2016: Journal of Chiropractic Humanities
https://www.readbyqxmd.com/read/27920593/slipped-capital-femoral-epiphysis-and-primary-hyperparathyroidism-a-case-report
#6
Anas A Alghamdi, Maswood M Ahmad, Mussa H Almalki
The aim of reporting this case is to highlight the association of two disorders, primary hyperparathyroidism (PHPT) and slipped capital femoral epiphysis (SCFE). They are usually seen in two different age groups and rarely together. PHPT is a rare cause of SCFE and only 10 cases have been reported in the literature worldwide. The patient in our report is a 13-year-old girl who presented to our clinic with bilateral knee pain and a waddling gait. Subsequent investigations showed that she had PHPT and SCFE with low bone mass...
2016: Clinical Medicine Insights. Endocrinology and Diabetes
https://www.readbyqxmd.com/read/27920563/assessing-parasite-clearance-during-uncomplicated-plasmodium-falciparum-infection-treated-with-artesunate-monotherapy-in-suriname
#7
Stephen Gs Vreden, Rakesh D Bansie, Jeetendra K Jitan, Malti R Adhin
BACKGROUND: Artemisinin resistance in Plasmodium falciparum is suspected when the day 3 parasitemia is >10% when treated with artemisinin-based combination therapy or if >10% of patients treated with artemisinin-based combination therapy or artesunate monotherapy harbored parasites with half-lives ≥5 hours. Hence, a single-arm prospective efficacy trial was conducted in Suriname for uncomplicated P. falciparum infection treated with artesunate-based monotherapy for 3 days assessing day 3 parasitemia, treatment outcome after 28 days, and parasite half-life...
2016: Infection and Drug Resistance
https://www.readbyqxmd.com/read/27920416/re-evaluating-the-inhibition-of-stress-erosions-revise-a-protocol-for-pilot-randomized-controlled-trial
#8
Waleed Alhazzani, Gordon Guyatt, John C Marshall, Richard Hall, John Muscedere, Francois Lauzier, Lehana Thabane, Mohammed Alshahrani, Shane W English, Yaseen M Arabi, Adam M Deane, Tim Karachi, Bram Rochwerg, Simon Finfer, Nick Daneman, Nicole Zytaruk, Diane Heel-Ansdell, Deborah Cook, On Behalf Of
INTRODUCTION: Clinicians routinely administer stress ulcer prophylaxis to mechanically ventilated patients in the intensive care unit (ICU), most commonly prescribing proton pump inhibitors (PPIs). However, the incidence of gastrointestinal (GI) bleeding from stress ulceration is low and recent observational studies suggest these agents may increase infections. Therefore, a large randomized clinical trial (RCT) is needed to inform modern practice. The aim of this multicenter pilot trial is to determine the feasibility of performing a large RCT to investigate the efficacy and safety of withholding intravenous pantoprazole...
November 2016: Annals of Saudi Medicine
https://www.readbyqxmd.com/read/27919584/assessment-of-population-exposure-to-pm2-5-for-mortality-in-china-and-its-public-health-benefit-based-on-benmap
#9
Li Chen, Mengshuang Shi, Shuang Gao, Suhuan Li, Jian Mao, Hui Zhang, Yanling Sun, Zhipeng Bai, Zhongliang Wang
Along with the rapid socioeconomic development, air pollution in China has become a severe problem. One component of air pollution, in particular, PM2.5 has aroused wide public concern because of its high concentration. In this study, data were collected from over 900 monitoring sites of the newly constructed PM2.5 monitoring network in China. The interpolation methods were used to simulate the PM2.5 exposure level of China especially in rural areas, thus reflecting the spatial variation of PM2.5 pollution...
December 2, 2016: Environmental Pollution
https://www.readbyqxmd.com/read/27919383/social-capital-and-transaction-cost-on-co-creating-it-value-towards-inter-organizational-emr-exchange
#10
Hsin Hsin Chang, Chung-Jye Hung, Ching Ying Huang, Kit Hong Wong, Yi Ju Tsai
This study adopts social capital theory and transaction cost theory to explore the feasibility of an inter-organizational cross-hospital electronic medical records (EMR) exchange system, and the factors that affect its adoption. The concept of value co-creation is also used to assess such a system, and its influence on the performance of participating medical institutes. This research collected 330 valid paper-based questionnaires from the medical staff of various institutes. The results showed that social interaction ties and shared vision positively affected medical institutes' willingness to adopt the EMR exchange system, while asset specificity and uncertainty increased the related transaction costs...
January 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/27918636/4d-printing-of-shape-memory-based-personalized-endoluminal-medical-devices
#11
Matt Zarek, Nicola Mansour, Shir Shapira, Daniel Cohn
The convergence of additive manufacturing and shape-morphing materials is promising for the advancement of personalized medical devices. The capability to transform 3D objects from one shape to another, right off the print bed, is known as 4D printing. Shape memory thermosets can be tailored to have a range of thermomechanical properties favorable to medical devices, but processing them is a challenge because they are insoluble and do not flow at any temperature. This study presents here a strategy to capitalize on a series of medical imaging modalities to construct a printable shape memory endoluminal device, exemplified by a tracheal stent...
December 5, 2016: Macromolecular Rapid Communications
https://www.readbyqxmd.com/read/27917356/response-and-recovery-measures-for-two-floods-in-north-china-during-the-nineteenth-century-a-comparative-study
#12
Yu Ye, Xiuqi Fang, Fan Li
BACKGROUND: The process of human response to natural disasters and its mechanisms as revealed by historical events still has a broad significance for modern society. This study analyzed the disaster relief process and the social response for two floods in China: the Yongding River flood in 1801 and the Yellow River flood in 1841. These two floods reflect the different response processes between the national and provincial capitals during a stage of climate cooling and social transition in the Qing dynasty...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27917302/characterization-of-the-blood-brain-barrier-in-pediatric-central-nervous-system-neoplasms
#13
Christopher S Hong, Winson Ho, Martin G Piazza, Abhik Ray-Chaudhury, Zhengping Zhuang, John D Heiss
OBJECTIVE: The normal blood-brain barrier (BBB) is composed of tight junctions between endothelial cells and surrounding astrocyte foot processes. Breakdown of the physiological astrocyte-endothelial cell relationship occurs in adult metastatic and primary brain tumors. However, the astrocyte-endothelial cell relationship has not been studied in pediatric tumors. MATERIALS AND METHODS: Utilizing specimens from cases of pilocytic astrocytoma (n = 5), medulloblastoma (n = 5), and low-grade diffuse astrocytoma (n = 1), immunofluorescence were performed using primary antibodies against CD31, glial fibrillary acidic protein (GFAP), and aquaporin 4 (AQ4)...
2016: Journal of Interdisciplinary Histopathology
https://www.readbyqxmd.com/read/27917201/prevalence-of-intestinal-parasitic-infections-among-school-children-in-capital-areas-of-the-democratic-republic-of-s%C3%A3-o-tom%C3%A3-and-pr%C3%A3-ncipe-west-africa
#14
Chien-Wei Liao, Chung-Jung Fu, Cheng-Yan Kao, Yueh-Lun Lee, Po-Ching Chen, Ting-Wu Chuang, Toshio Naito, Chia-Mei Chou, Ying-Chie Huang, Idalina Bonfim, Chia-Kwung Fan
BACKGROUND: Although the Democratic Republic of Sao Tome and Principe (DRSTP) has undertaken school children-based deworming programs against intestinal parasitic infections (IPIs) using a single dose of mebendazole annually since 2005, it remains unclear as to the outcome to date. The present study intends to investigate the recent IPIs status among school children living in capital areas of the DRSTP. METHODS: A total of 252 school children (121 boys and 131 girls) of grades 4 and 5 from 4 primary schools located in the capital areas participated in the present study and their fresh fecal specimens were examined for the presence of any parasites using the merthiolate-iodine-formaldehyde concentration method as conducted...
September 2016: African Health Sciences
https://www.readbyqxmd.com/read/27916914/comparing-sanitation-delivery-modalities-in-urban-informal-settlement-schools-a-randomized-trial-in-nairobi-kenya
#15
Kate Bohnert, Anna N Chard, Alex Mwaki, Amy E Kirby, Richard Muga, Corey L Nagel, Evan A Thomas, Matthew C Freeman
The provision of safely managed sanitation in informal settlements is a challenge, especially in schools that require durable, clean, sex-segregated facilities for a large number of children. In informal settlements in Nairobi, school sanitation facilities demand considerable capital costs, yet are prone to breakage and often unhygienic. The private sector may be able to provide quality facilities and services to schools at lower costs as an alternative to the sanitation that is traditionally provided by the government...
November 30, 2016: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/27916504/the-state-of-play-and-future-of-antibody-therapeutics
#16
REVIEW
Zehra Elgundi, Mouhamad Reslan, Esteban Cruz, Vicki Sifniotis, Veysel Kayser
It has been over four decades since the development of monoclonal antibodies (mAbs) using a hybridoma cell line was first reported. Since then more than thirty therapeutic antibodies have been marketed, mostly as oncology, autoimmune and inflammatory therapeutics. While antibodies are very efficient, their cost-effectiveness has always been discussed owing to their high costs, accumulating to more than one billion dollars from preclinical development through to market approval. Because of this, therapeutic antibodies are inaccessible to some patients in both developed and developing countries...
December 1, 2016: Advanced Drug Delivery Reviews
https://www.readbyqxmd.com/read/27916434/competition-policy-for-health-care-provision-in-norway
#17
Kurt R Brekke, Odd Rune Straume
Competition policy has played a very limited role for health care provision in Norway. The main reason is that Norway has a National Health Service (NHS) with extensive public provision and a wide set of sector-specific regulations that limit the scope for competition. However, the last two decades, several reforms have deregulated health care provision and opened up for provider competition along some dimensions. For specialised care, the government has introduced patient choice and (partly) activity (DRG) based funding, but also corporatised public hospitals and allowed for more private provision...
November 23, 2016: Health Policy
https://www.readbyqxmd.com/read/27916034/-the-mid-to-long-term-effect-of-wallis-lumbar-interspinous-dynamic-stabilization-on-the-adjacent-segment-degeneration
#18
X Yuan, C Kong, X M Chen, L B Cui, S J Xu, Y D Liu
Objective: To explore the mid- to long-term effect of Wallis interspinous dynamic stabilization system on the adjacent segment degeneration. Methods: From March 2009 to June 2010, in Department of Orthopedics, Beijing Luhe Hospital, Capital Medical University, 24 patients with L4-5 monosegmental lumbar disc herniation were treated with posterior lumbar decompression combined with Wallis interspinous dynamic fixation. Clinical outcomes were evaluated with visual analogue score (VAS) (back pain), VAS (leg pain) and oswestry disability index (ODI) score...
December 1, 2016: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/27915478/targeting-the-phosphatidylinositol-3-kinase-pathway-in-gastric-cancer-can-omics-improve-outcomes
#19
REVIEW
Phu Tran, Cham Nguyen, Samuel J Klempner
Phosphatidylinositol-3-kinase (PI3K) pathway signaling is an established oncogenic signal transduction pathway implicated in multiple malignancies. Therapeutic targeting of PI3K pathway components has improved outcomes in chronic lymphocytic leukemia, kidney cancer, breast cancer, and neuroendocrine tumors. Gastric cancers harbor some of the highest rates of oncogenic alterations in PI3K but attempts to translate this genomic observation have met with limited clinical success and novel approaches are needed...
November 2016: International Neurourology Journal
https://www.readbyqxmd.com/read/27915316/lack-of-screening-underlies-most-stage-5-retinopathy-of-prematurity-among-cases-presenting-to-a-tertiary-eye-center-in-india
#20
Rajvardhan Azad, Parijat Chandra, Anil Gangwe, Vivek Kumar
OBJECTIVE: To study the barriers to effective screening, early detection and treatment of Retinopathy of Prematurity leading to advanced disease. DESIGN: Cross-sectional study. SETTING: Tertiary eye care hospital in northern India. PARTICIPANTS: 115 babies with bilateral stage 5 ROP identified amongst 354 preterm infants examined over a one year period. METHODS: Information regarding gestational age, birthweight, duration of stay in nursery, duration of supplemental oxygen therapy and treatment details were obtained from discharge summary when available, and by interviewing carers...
November 7, 2016: Indian Pediatrics
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