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https://www.readbyqxmd.com/read/29351498/high-power-diode-laser-on-management-of-drug-induced-gingival-overgrowth-report-of-two-cases-and-long-term-follow-up
#1
Luana Campos, Marina Gallottini, Débora Pallos, Alyne Simões, Fabiana Martins
BACKGROUND: Drug-induced gingival overgrowth (DIGO) is attributed mainly to the prolonged use of calcium channel blocking agents, anticonvulsants, and anti-calcineurin inhibitors . The management of DIGO depends on the severity of the disease and includes surgical intervention and plaque control. Compared to conventional surgical treatment, the recent literature data have shown that gingivectomy using a high-power laser (HPL) is a short and easy procedure, which results in minimal postoperative discomfort and greater patient accep- tance...
January 19, 2018: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/29351398/visceral-hypersensitivity-induced-by-optogenetic-activation-of-the-amygdala-in-conscious-rats
#2
Anthony C Johnson, Rocco Latorre, Casey O Ligon, Beverley Greenwood-Van Meerveld
In vivo optogenetics identifies brain circuits controlling behaviors in conscious animals by using light to alter neuronal function and offers a novel tool to study the brain-gut axis. Using adenoviral-mediated expression, we aimed to investigate whether photoactivation with channelrhodopsin (ChR2) or photoinhibition with halorhodopsin (HR3.0) of fibers originating from the central nucleus of the amygdala (CeA) at the bed nucleus of the stria terminalis (BNST) had any effect on colonic sensitivity. We also investigated whether that there was any deleterious effect of the adenovirus on the neuronal population or the neuronal phenotype within the CeA-BNST circuitry activated during the optogenetic stimulation...
December 14, 2017: American Journal of Physiology. Gastrointestinal and Liver Physiology
https://www.readbyqxmd.com/read/29351334/endothelin-1-is-associated-with-fibrosis-in-proliferative-diabetic-retinopathy-membranes
#3
William Chang, Michelle Lajko, Amani A Fawzi
PURPOSE: To characterize the relationship between endothelin-1 and fibrosis in epiretinal membranes in proliferative diabetic retinopathy and explore the role of endothelial-mesenchymal transition in these membranes. METHODS: Membranes were obtained from eyes undergoing pars plana vitrectomy for complicated proliferative diabetic retinopathy or idiopathic epiretinal membrane. Through standard immunohistochemical techniques, we labeled membranes to explore the distribution of endothelin-1 and endothelin receptor B, comparing proliferative diabetic retinopathy and idiopathic epiretinal membranes...
2018: PloS One
https://www.readbyqxmd.com/read/29350964/generation-of-high-power-high-intensity-short-x-ray-free-electron-laser-pulses
#4
Marc W Guetg, Alberto A Lutman, Yuantao Ding, Timothy J Maxwell, Franz-Josef Decker, Uwe Bergmann, Zhirong Huang
X-ray free-electron lasers combine a high pulse power, short pulse length, narrow bandwidth, and high degree of transverse coherence. Any increase in the photon pulse power, while shortening the pulse length, will further push the frontier on several key x-ray free-electron laser applications including single-molecule imaging and novel nonlinear x-ray methods. This Letter shows experimental results at the Linac Coherent Light Source raising its maximum power to more than 300% of the current limit while reducing the photon pulse length to 10 fs...
January 5, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/29350959/under-the-tunneling-barrier-recollisions-in-strong-field-ionization
#5
Michael Klaiber, Karen Z Hatsagortsyan, Christoph H Keitel
A new pathway of strong-laser-field-induced ionization of an atom is identified which is based on recollisions under the tunneling barrier. With an amended strong-field approximation, the interference of the direct and the under-the-barrier recolliding quantum orbits are shown to induce a measurable shift of the peak of the photoelectron momentum distribution. The scaling of the momentum shift is derived relating the momentum shift to the tunneling delay time according to the Wigner concept. This allows us to extend the Wigner concept for the quasistatic tunneling time delay into the nonadiabatic domain...
January 5, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/29350950/local-melting-attracts-grain-boundaries-in-colloidal-polycrystals
#6
Caitlin E Cash, Jeremy Wang, Maya M Martirossyan, B Kemper Ludlow, Alejandro E Baptista, Nina M Brown, Eli J Weissler, Jatin Abacousnac, Sharon J Gerbode
We find that laser-induced local melting attracts and deforms grain boundaries in 2D colloidal crystals. When a melted region in contact with the edge of a crystal grain recrystallizes, it deforms the grain boundary-this attraction is driven by the multiplicity of deformed grain boundary configurations. Furthermore, the attraction provides a method to fabricate artificial colloidal crystal grains of arbitrary shape, enabling new experimental studies of grain boundary dynamics and ultimately hinting at a novel approach for fabricating materials with designer microstructures...
January 5, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/29350937/light-stops-at-exceptional-points
#7
Tamar Goldzak, Alexei A Mailybaev, Nimrod Moiseyev
Almost twenty years ago, light was slowed down to less than 10^{-7} of its vacuum speed in a cloud of ultracold atoms of sodium. Upon a sudden turn-off of the coupling laser, a slow light pulse can be imprinted on cold atoms such that it can be read out and converted into a photon again. In this process, the light is stopped by absorbing it and storing its shape within the atomic ensemble. Alternatively, the light can be stopped at the band edge in photonic-crystal waveguides, where the group speed vanishes...
January 5, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/29350880/temporal-and-spatial-quantification-of-pain-related-small-fiber-functionality-assessed-using-laser-speckle-contrast-analysis-lasca
#8
Isin Unal-Cevik
BACKGROUND: This study aimed to establish a practical method for assessing pain symptomatology and develop criteria for quantifying small fiber functions, using LASCA. METHODS: Axon flare responses, which reflect small fiber functions, were induced either by histamine or capsaicin applied to the volar surface of the skin of the left forearm. To inhibit small fiber function, local anesthetic cream was applied to the skin of right forearm. The effects on pain symptomatology (severity/timing) and axon flare responses (temporal/spatial characteristics) were measured using LASCA...
January 19, 2018: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/29350743/facile-preparation-of-carbon-dot-supported-nanoflowers-for-efficient-photothermal-therapy-of-cancer-cells
#9
Changshun Hou, Shiqing Chen, Mengqi Wang
Herein, novel self-assembled red-emissive C-dots@Au nanoflowers were developed, and they demonstrated efficient photothermal properties under 750 nm laser irradiation. Moreover, C-dots@Au nanoflowers showed the ability of simultaneous photoacoustic and fluorescence imaging. Our study may provide a novel strategy for the efficient phototherapy of cancer cells based on C-dots.
January 19, 2018: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/29350715/simulation-of-ktp-laser-based-zenker-diverticulotomy-with-a-porcine-model-and-laryngeal-dissection-station
#10
Matthew R Hoffman, Heidi Kletzien, Seth H Dailey, J Scott McMurray
Zenker's diverticulum is a rare cause of progressive dysphagia that is treated surgically. KTP laser-based diverticulotomy is one effective treatment. Developing a simulation model is helpful for rare conditions. Pigs have a natural hypopharyngeal pouch similar to a diverticulum. We present a model for performing rigid endoscopic KTP laser diverticulotomy in a porcine model using a laryngeal dissection station. Eleven pigs were examined to confirm presence of the hypopharyngeal pouch. A specimen was mounted on the modified laryngeal dissection station and a KTP laser-based diverticulotomy was performed...
December 2017: OTO Open
https://www.readbyqxmd.com/read/29350625/dynamically-tunable-interface-states-in-1d-graphene-embedded-photonic-crystal-heterostructure
#11
Zhao Huang, Shuaifeng Li, Xin Liu, Degang Zhao, Lei Ye, Xuefeng Zhu, Jianfeng Zang
Optical interface states exhibit promising applications in nonlinear photonics, low-threshold lasing, and surface-wave assisted sensing. However, the further application of interface states in configurable optics is hindered by their limited tunability. Here, we demonstrate a new approach to generate dynamically tunable and angle-resolved interface states using graphene-embedded photonic crystal (GPC) heterostructure device. By combining the GPC structure design with in situ electric doping of graphene, a continuously tunable interface state can be obtained and its tuning range is as wide as the full bandgap...
January 19, 2018: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/29350540/express-analytical-methods-to-distinguish-the-positive-and-negative-spectra-of-mineral-and-environmental-elements-using-deep-ablation-laser-induced-breakdown-spectroscopy-libs
#12
Dongyoung Kim, Junho Yang, Soo-Jin Choi, Jack Yoh
No abstract text is available yet for this article.
January 1, 2018: Applied Spectroscopy
https://www.readbyqxmd.com/read/29350426/efficacy-of-photodynamic-therapy-in-the-treatment-of%C3%A2-symptomatic-oral-lichen-planus-a-systematic-review
#13
REVIEW
Sadeq Ali Al-Maweri, Sajna Ashraf, Butchibabu Kalakonda, Esam Halboub, Waleed Petro, Nader Ahmed AlAizari
BACKGROUND: The aim of the present study was to systematically review the efficacy of photodynamic therapy (PDT) in the management of symptomatic oral lichen planus (OLP). MATERIALS AND METHODS: PubMed/MEDLINE, Scopus, and ISI Web of knowledge were searched until July 2017, using the following keywords: oral lichen planus, erosive lichen planus, lichen planus, and photodynamic therapy. RESULTS: Five clinical studies were included. The risk of bias was considered high in four studies and moderate in one study...
January 19, 2018: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/29350315/revisiting-embryo-assisted-hatching-approaches-a-systematic-review-of-the-current-protocols
#14
REVIEW
Alessandra Alteri, Paola Viganò, Ahmad Abu Maizar, Luca Jovine, Elisa Giacomini, Patrizia Rubino
Zona pellucida (ZP) manipulation, termed "assisted hatching" (AH), has been introduced in order to favor embryo hatching and ultimately improve assisted reproductive technology success but with poor proofs of safety and biological plausibility. We herein provide a systematic review of clinical outcomes following the application of different methods of ZP manipulation on fresh or frozen/thawed embryos at different developmental stages in different groups of patients. Out of the 69 papers that compared the clinical outcomes deriving from hatched versus non-hatched embryos, only 11 considered blastocysts while the rest referred to cleavage stage embryos...
January 19, 2018: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/29350231/tuning-the-sensitivity-of-lanthanide-activated-nir-nanothermometers-in-the-biological-windows
#15
P Cortelletti, A Skripka, C Facciotti, M Pedroni, G Caputo, N Pinna, M Quintanilla, A Benayas, F Vetrone, A Speghini
Lanthanide-activated SrF2 nanoparticles with a multishell architecture were investigated as optical thermometers in the biological windows. A ratiometric approach based on the relative changes in the intensities of different lanthanide (Nd3+ and Yb3+) NIR emissions was applied to investigate the thermometric properties of the nanoparticles. It was found that an appropriate doping with Er3+ ions can increase the thermometric properties of the Nd3+-Yb3+ coupled systems. In addition, a core containing Yb3+ and Tm3+ can generate light in the visible and UV regions upon near-infrared (NIR) laser excitation at 980 nm...
January 19, 2018: Nanoscale
https://www.readbyqxmd.com/read/29350038/efficient-mass-spectral-analysis-of-active-transporters-overexpressed-in-escherichia-coli
#16
Mamiyo Kawakami, Narinobu Juge, Yuri Kato, Hiroshi Omote, Yoshinori Moriyama, Takaaki Miyaji
Structural analysis of purified active membrane proteins can be performed by mass spectrometry (MS). However, no large-scale expression systems for active eukaryotic membrane proteins are available. Moreover, because membrane proteins cannot easily be digested by trypsin and ionized, they are difficult to analyze by MS. Here, we developed a method for mass spectral analysis of eukaryotic membrane proteins combined to an overexpression system in Escherichia coli. Vesicular glutamate transporter 2 (VGLUT2/SLC17A6) with a soluble α-helical protein and histidine tag on the N- and C-terminus, respectively, was overexpressed in E...
January 19, 2018: Journal of Proteome Research
https://www.readbyqxmd.com/read/29350027/evaluation-of-drug-exposure-and-metabolism-in-locust-and-zebrafish-brains-using-mass-spectrometry-imaging
#17
Marvin Villacrez, Karin Hellman, Tatsuya Ono, Yutaka Sugihara, Melinda Rezeli, Fredrik Ek, Gyorgy Marko-Varga, Roger Olsson
Studying how and where drugs are metabolized in the brain is challenging. In an entire organism, peripheral metabolism produces many of the same metabolites as those in the brain, and many of these metabolites can cross the blood-brain barrier from the periphery, thus making the relative contributions of hepatic and brain metabolism difficult to study in vivo. In addition, drugs and metabolites contained in ventricles and in the residual blood of capillaries in the brain may overestimate drugs' and metabolites' concentrations in the brain...
January 19, 2018: ACS Chemical Neuroscience
https://www.readbyqxmd.com/read/29349877/engineered-and-laser-processed-chitosan-biopolymers-for-sustainable-and-biodegradable-triboelectric-power-generation
#18
Ruoxing Wang, Shengjie Gao, Zhen Yang, Yule Li, Weinong Chen, Benxin Wu, Wenzhuo Wu
Recent advances achieved in triboelectric nanogenerators (TENG) focus on boosting power generation and conversion efficiency. Nevertheless, obstacles concerning economical and biocompatible utilization of TENGs continue to prevail. Being an abundant natural biopolymer from marine crustacean shells, chitosan enables exciting opportunities for low-cost, biodegradable TENG applications in related fields. Here, the development of biodegradable and flexible TENGs based on chitosan is presented for the first time...
January 19, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29349874/assessment-by-matrix-assisted-laser-desorption-ionization-time-of-flight-mass-spectrometry-of-the-effects-of-preanalytical-variables-on-serum-peptidome-profiles-following-long-term-sample-storage
#19
Sachio Tsuchida, Mamoru Satoh, Hiroshi Umemura, Kazuyuki Sogawa, Masaki Takiwaki, Takayuki Ishige, Yui Miyabayashi, Yuuya Iwasawa, Sohei Kobayashi, Minako Beppu, Motoi Nishimura, Yoshio Kodera, Kazuyuki Matsushita, Fumio Nomura
PURPOSE: Human serum and plasma are often used as clinical specimens in proteomics analyses, and peptidome profiling of human serum is a promising tool for identifying novel disease-associated biomarkers. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) is widely used for peptidomic biomarker discovery. Careful sample collection and handling are required as either can have a profound impact on serum peptidome patterns, yet the effects of preanalytical variables on serum peptidome profiles have not been completely elucidated...
January 19, 2018: Proteomics. Clinical Applications
https://www.readbyqxmd.com/read/29349714/dbda-as-a-novel-matrix-for-the-analyses-of-small-molecules-and-quantification-of-fatty-acids-by-negative-ion-maldi-tof-ms
#20
Ling Ling, Ying Li, Sheng Wang, Liming Guo, Chunsheng Xiao, Xuesi Chen, Xinhua Guo
Matrix interference ions in low mass range has always been a concern when using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) to analyze small molecules (<500 Da). In this work, a novel matrix, N1,N4-dibenzylidenebenzene-1,4-diamine (DBDA) was synthesized for the analyses of small molecules by negative ion MALDI-TOF MS. Notably, only neat ions ([M-H]-) of fatty acids without matrix interference appeared in the mass spectra and the limit of detection (LOD) reached 0...
January 18, 2018: Journal of the American Society for Mass Spectrometry
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