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https://www.readbyqxmd.com/read/28550708/rapid-sealing-of-porcine-renal-blood-vessels-ex-vivo-using-a-high-power-1470-nm-laser-and-laparoscopic-prototype
#1
Luke A Hardy, Thomas C Hutchens, Eric R Larson, David A Gonzalez, Chun-Hung Chang, William H Nau, Nathaniel M Fried
No abstract text is available yet for this article.
May 1, 2017: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/28550642/post-heroin-dose-tissue-distribution-of-6-monoacetylmorphine-6-mam-with-maldi-imaging
#2
Belin G Teklezgi, Annapurna Pamreddy, Sooraj Baijnath, Nirmala D Gopal, Tricia Naicker, Hendrik G Kruger, Thavendran Govender
Heroin is an illicit opioid drug which is commonly abused and leads to dependence and addiction. Heroin is considered a pro-drug and is rapidly converted to its major active metabolite 6-monoacetylmorphine (6-MAM) which mediates euphoria and reward through the stimulation of opioid receptors in the brain. The aim of this study was to investigate the distribution and localization of 6-MAM in the healthy Sprague Dawley rat brain following intraperitoneal (i.p) administration of heroin (10 mg/kg), using matrix-assisted laser desorption/ionization mass spectrometric imaging (MALDI-MSI), in combination with quantification via liquid chromatography mass spectrometry (LC-MS/MS)...
May 26, 2017: Journal of Molecular Histology
https://www.readbyqxmd.com/read/28550404/development-of-an-imaging-system-for-in-vivo-real-time-monitoring-of-neuronal-activity-in-deep-brain-of-free-moving-rats
#3
Norio Iijima, Shinji Miyamoto, Keisuke Matsumoto, Ken Takumi, Yoichi Ueta, Hitoshi Ozawa
We have newly developed a system that allows monitoring of the intensity of fluorescent signals from deep brains of rats transgenically modified to express enhanced green fluorescent protein (eGFP) via an optical fiber. One terminal of the optical fiber was connected to a blue semiconductor laser oscillator/green fluorescence detector. The other terminal was inserted into the vicinity of the eGFP-expressing neurons. Since the optical fiber was vulnerable to twisting stresses caused by animal movement, we also developed a cage in which the floor automatically turns, in response to the turning of the rat's head...
May 26, 2017: Histochemistry and Cell Biology
https://www.readbyqxmd.com/read/28550338/a-comparative-study-of-modified-transcanalicular-diode-laser-dacryocystorhinostomy-versus-conventional-transcanalicular-diode-laser-dacryocystorhinostomy
#4
Eduardo Damous Feijó, Juliana Alves Caixeta, Ana Carla de Souza Nery, Roberto Murillo Limongi, Suzana Matayoshi
External dacryocystorhinostomy (DCR) is the gold standard surgical technique for the treatment of primary acquired nasolacrimal duct obstruction (PANDO). However, new techniques such as endoscopic DCR and transcanalicular dacryocystorhinostomy (T-DCR) are being studied in an attempt to reduce surgical time, avoid external scarring and preserve the lacrimal pump while achieving the same efficacy. The purpose of this study was to compare the efficacy between conventional T-DCR and modified transcanalicular dacryocystorhinostomy (MT-DCR) in patients with PANDO...
May 26, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28549845/tomographic-analysis-of-anterior-posterior-and-total-corneal-refractive-power-changes-after-femtosecond-laser-assisted-keratotomy
#5
Franziska Löffler, Myriam Böhm, Michael Herzog, Kerstin Petermann, Thomas Kohnen
PURPOSE: To analyze the effect of penetrating femtosecond laser-assisted keratotomy (pFLAK) during laser lens surgery on anterior, posterior corneal astigmatism and total corneal refractive power (TCRP) astigmatism (CAant, CApost, CATCRP) measured with Scheimpflug tomography. DESIGN: Prospective, interventional case series. METHODS: This institutional study included 27 eyes of 23 patients (65 ± 8 years) with low to moderate CATCRP determined with Scheimpflug tomography (Pentacam HR) after penetrating femtosecond laser-assisted keratotomy (pFLAK) and laser lens surgery...
May 23, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28549769/variations-in-the-cerebrospinal-fluid-proteome-following-traumatic-brain-injury-and-subarachnoid-hemorrhage
#6
David E Connor, Ganta V Chaitanya, Prashant Chittiboina, Paul McCarthy, L Keith Scott, Lisa Schrott, Alireza Minagar, Anil Nanda, J Steven Alexander
BACKGROUND: Proteomic analysis of cerebrospinal fluid (CSF) has shown great promise in identifying potential markers of injury in neurodegenerative diseases [1-13]. Here we compared CSF proteomes in healthy individuals, with patients diagnosed with traumatic brain injury (TBI) and subarachnoid hemorrhage (SAH) in order to characterize molecular biomarkers which might identify these different clinical states and describe different molecular mechanisms active in each disease state. METHODS: Patients presenting to the Neurosurgery service at the Louisiana State University Hospital-Shreveport with an admitting diagnosis of TBI or SAH were prospectively enrolled...
May 13, 2017: Pathophysiology: the Official Journal of the International Society for Pathophysiology
https://www.readbyqxmd.com/read/28549566/asymmetrical-responses-of-skin-blood-flow-in-ischemic-hindlimbs-to-electrical-stimulation-of-the-unilateral-forelimb
#7
Chung-Shin Huang, Ya-Hui Sun, Yi-Ting Wang, Yu-Hung Pan, Shwu-Fen Wang, Yuan-Feen Tsai
The regulation of skin blood flow (SBF) is primarily mediated by the sympathetic nervous system, but the effects of electrical stimulation (ES) of one limb on SBF in the other limbs remain unknown. The present study investigated the effects of unilateral forelimb ES on SBF in the bilateral hindlimbs in anesthetized rats. Bilateral hindlimb ischemia was induced by tourniquet application for 60min. After reperfusion for 24h, ES (3 or 125Hz) was applied to the upper one-fourth of the triceps brachii muscle of the left or right forelimb for 30min...
May 23, 2017: Microvascular Research
https://www.readbyqxmd.com/read/28549467/the-prediction-diagnosis-and-management-of-complications-in-monochorionic-twin-pregnancies-the-ommit-optimal-management-of-monochorionic-twins-study
#8
Fiona L Mackie, R Katie Morris, Mark D Kilby
BACKGROUND: Monochorionic twin pregnancies are at increased risk of complications due to sharing a single placenta and potentially developing unbalanced vascular anastomoses. Complications include twin-twin transfusion syndrome (TTTS) which affects 10-15% monochorionic twins, and if untreated has a 70-90% perinatal loss rate. We are currently unable to predict which twins will develop complications or to what severity. We have previously shown differences in angiogenic and placental growth factors in maternal blood in pregnancies complicated by TTTS compared to twin pregnancies not complicated by TTTS but matched for gestation...
May 26, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28549319/effect-of-laser-photobiomodulation-on-wound-healing-and-postoperative-pain-following-free-gingival-graft-a-split-mouth-triple-blind-randomized-controlled-clinical-trial
#9
Mohadeseh Heidari, Mojgan Paknejad, Raika Jamali, Hanieh Nokhbatolfoghahaei, Reza Fekrazad, Neda Moslemi
BACKGROUND AND AIM: Free gingival graft (FGG) is one of the most predictable techniques for gingival augmentation. However, patient's discomfort and pain during healing period are significant concerns. The aim of this study was to assess if laser photobiomodulation (PBM) was effective in terms of enhancing wound healing and reducing postoperative pain. METHODS AND MATERIALS: Twelve patients participated in this split-mouth randomized controlled clinical trial. Each patient had a 30-day interval between the two procedures...
May 18, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28549144/video-assisted-thoracoscopic-surgery-approach-for-transmyocardial-laser-revascularization
#10
Mohammad A Bashir, Brandon C Lyle, Ali S Nasr, Kalpaj Parekh
Transmyocardial laser revascularization is an established therapy for refractory coronary artery disease. However, utilization of the technology is not as widespread as expected. This is despite the fact that the efficacy of the technology has been established in multiple prospective randomized trials. Furthermore, only about 5% of transmyocardial laser revascularization cases annually are performed in a minimally invasive fashion. We report a case of a female patient treated in a minimally invasive thoracoscopic fashion...
May 26, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28548673/laser-triggered-phase-transition-in-photothermal-liquid-crystals
#11
Mathieu Ciancone, Franck Camerel
Reversible high temperature phase transitions were easily induced under laser irradiation in pure thermotropic liquid crystals built around photothermal nickel-bis(dithiolene) cores. The strong photothermal activity of nickel-bis(dithiolene) liquid crystalline thin films allows reaching a temperature as high as 250 °C directly from room temperature in a few seconds with high spatial control.
May 26, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28548537/dispersive-time-delay-dynamical-systems
#12
Alexander Pimenov, Svetlana Slepneva, Guillaume Huyet, Andrei G Vladimirov
We present a theoretical approach to investigate the effect of dispersion in dynamical systems commonly described by time-delay models. The introduction of a polarization equation provides a means to introduce dispersion as a distributed delay term. The expansion of this term in power series, as usually performed to study the propagation of waves in spatially extended systems, can lead to the appearance of spurious instabilities. This approach is illustrated using a long cavity laser, where in the normal dispersion regime both the experiment and theory show a stable operation, while a modulation instability, commonly referred as the Benjamin-Feir instability, is observed in the anomalous dispersion regime...
May 12, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28548523/strength-and-viscosity-effects-on-perturbed-shock-front-stability-in-metals
#13
S Opie, E Loomis, P Peralta, T Shimada, R P Johnson
Computational modeling and experimental measurements on metal samples subject to a laser-driven, ablative Richtmyer-Meshkov instability showed differences between viscosity and strength effects. In particular, numerical and analytical solutions, coupled with measurements of fed-through perturbations, generated by perturbed shock fronts onto initially flat surfaces, show promise as a validation method for models of deviatoric response in the postshocked material. Analysis shows that measurements of shock perturbation amplitudes at low sample thickness-to-wavelength ratios are not enough to differentiate between strength and viscosity effects, but that surface displacement data of the fed-through perturbations appears to resolve the ambiguity...
May 12, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28548516/relativistic-electron-streaming-instabilities-modulate-proton-beams-accelerated-in-laser-plasma-interactions
#14
S Göde, C Rödel, K Zeil, R Mishra, M Gauthier, F-E Brack, T Kluge, M J MacDonald, J Metzkes, L Obst, M Rehwald, C Ruyer, H-P Schlenvoigt, W Schumaker, P Sommer, T E Cowan, U Schramm, S Glenzer, F Fiuza
We report experimental evidence that multi-MeV protons accelerated in relativistic laser-plasma interactions are modulated by strong filamentary electromagnetic fields. Modulations are observed when a preplasma is developed on the rear side of a μm-scale solid-density hydrogen target. Under such conditions, electromagnetic fields are amplified by the relativistic electron Weibel instability and are maximized at the critical density region of the target. The analysis of the spatial profile of the protons indicates the generation of B>10  MG and E>0...
May 12, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28548297/dysregulation-of-the-causative-genes-for-hereditary-parkinsonism-in-the-midbrain-in-parkinson-s-disease
#15
Yun Joong Kim, Junbeom Jeon, Jaemoon Shin, Nan Young Kim, Jeong Hoon Hong, Jae-Min Oh, SangKyoon Hong, Yeo Jin Kim, Young-Eun Kim, Suk Yun Kang, Hyeo-Il Ma, Unjoo Lee, Jeehee Yoon
BACKGROUND AND OBJECTIVES: Many hereditary movement disorders with complex phenotypes without a locus symbol prefix for familial PD present as parkinsonism; however, the dysregulation of genes associated with these phenotypes in the SNpc of PD patients has not been systematically studied. METHODS: Gene set enrichment analyses were performed using 10 previously published genome-wide expression datasets obtained by laser-captured microdissection of pigmented neurons in the SNpc...
May 26, 2017: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/28548228/skin-reactions-after-photodynamic-therapy-are-unaffected-by-839%C3%A2-nm-photobiomodulation-therapy-a-randomized-double-blind-placebo-controlled-clinical-trial
#16
Christiane Bay, Anne-Cathrine Vissing, Daniel Thaysen-Petersen, Catharina Margrethe Lerche, Katrine Togsverd-Bo, Jakob Heydenreich, Merete Haedersdal
BACKGROUND AND OBJECTIVE: Photodynamic therapy (PDT) is associated with erythema and edema. Photobiomodulation (PBM) therapy may stimulate the skin recovery process. We investigated the potential of PBM to reduce PDT-induced skin reactions. STUDY DESIGN AND METHODS: Healthy volunteers (n = 20) were randomized to receive left- or right side PBM (near-infrared 839/595 nm) or placebo-PBM (595 nm) on their buttocks. Corresponding test areas were exposed to standardized PDT reactions, using ablative fractional laser-assisted PDT (AFXL-PDT) with methyl-aminolevulinate (MAL) incubated for 30, 90, and 180 minutes before red-light illumination...
May 26, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28548126/microrna-dysregulation-in-the-tumor-microenvironment-influences-the-phenotype-of-pancreatic-cancer
#17
Eva Karamitopoulou, Stefan Haemmig, Ulrich Baumgartner, Cornelia Schlup, Martin Wartenberg, Erik Vassella
Cellular interactions in the tumor microenvironment influence neoplastic progression in pancreatic ductal adenocarcinoma. One underlying mechanism is the induction of the prognostically unfavorable epithelial-mesenchymal-transition-like tumor budding. Our aim is to explore the expression of microRNAs implicated in the regulation of tumor budding focusing on the microenvironment of the invasive front. To this end, RNA from laser-capture-microdissected material of the main tumor, tumor buds, juxta-tumoral stroma, tumor-remote stroma, and non-neoplastic pancreatic parenchyma from pancreatic cancer cases with (n=7) and without (n=6) tumor budding was analyzed by qRT-PCR for the expression of a panel of miRNAs that are known to be implicated in the regulation of epithelial-mesenchymal transition, including miR-21, miR-183, miR-200b, miR-200c, miR-203, miR-205, miR-210, and miR-217...
May 26, 2017: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/28547077/effects-of-the-combined-treatment-of-bone-marrow-stromal-cells-with-mild-exercise-and-thyroid-hormone-on-brain-damage-and-apoptosis-in-a-mouse-focal-cerebral-ischemia-model
#18
Kobar Akhoundzadeh, Abedin Vakili, Hamid Reza Sameni, Abbas Ali Vafaei, Ali Rashidy-Pour, Manouchehr Safari, Razieh Mohammadkhani
This study examined whether post-stroke bone marrow stromal cells (BMSCs) therapy combined with exercise (EX) and/or thyroid hormone (TH) could reduce brain damage in an experimental ischemic stroke in mice. Focal cerebral ischemia was induced under Laser Doppler Flowmetry (LDF) guide by 45 min of middle cerebral artery occlusion (MCAO), followed by 7 days of reperfusion in albino mice. BMSCs were injected into the right cerebral ventricle 24 h after MCAO, followed by daily injection of T3 (20 μg/100 g weight S...
May 25, 2017: Metabolic Brain Disease
https://www.readbyqxmd.com/read/28547074/laser-assisted-hatching-of-human-embryos-may-two-alternative-approaches-thinning-versus-drilling-impact-on-implant-rate
#19
Francesco Padula, Stella Capriglione, Paola Iaconianni, Simona Gatti, Assunta Lippa, Salvatrice Elisa Minutolo, Diana Giannarelli, Claudio Giorlandino
No abstract text is available yet for this article.
May 25, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28547073/the-influence-of-low-intensity-he-ne-laser-on-the-wound-healing-in-diabetic-rats
#20
Maha Eissa, Wasil H M Salih
The low-level laser irradiation at certain wavelengths is reported to facilitate the healing process of diabetic wounds. Thus, this study carried out to look for the suitable laser parameters that could speed up the healing process. Fourteen healthy male and female rats were used in which a circular wound with a diameter of 2.5 ± 0.2 cm was created on the dorsum in each rat after injected them with alloxan to induced diabetic. They have been divided into two groups: control group (N = 7) and study group (N = 7) to conduct the study...
May 25, 2017: Lasers in Medical Science
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