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https://www.readbyqxmd.com/read/28222264/graphene-ink-laminate-structures-on-polyvinylidene-difluoride-pvdf-for-pyroelectric-thermal-energy-harvesting-and-waste-heat-recovery
#1
Daniel Zabek, Kris Seunarine, Chris Spacie, Chris R Bowen
Thermal energy can be effectively converted into electricity using pyroelectrics, which act as small scale power generator and energy harvesters providing nW to mW of electrical power. In this paper, a novel pyroelectric harvester based on free standing polyvinilidene difluoride (PVDF) was manufactured that exploits the high thermal radiation absorbance of a screen printed graphene-ink electrode structure to facilitate the conversion of the available thermal radiation energy into electrical energy. The interconnected graphene nanoplatelets (GNPs) enable high thermal radiation absorbance and high electrical conductivity along with the ease of deposition using a screen print technique...
February 21, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28221913/an-immunoassay-for-quantification-of-contamination-by-raw-meat-juice-on-food-contact-surfaces
#2
Fur-Chi Chen, Sandria Godwin, Edgar Chambers
Raw chicken products often are contaminated with Salmonella and Campylobacter , which can be transmitted from packages to contact surfaces. Raw meat juices from these packages also provide potential media for cross-contamination. There are limited quantitative data on the levels of consumer exposure to raw meat juice during shopping for and handling of chicken products. An exposure assessment is needed to quantify the levels of transmission and to assess the risk. An enzyme-linked immunosorbent assay (ELISA) was developed and validated for quantitative detection of raw meat juice on hands and various food contact surfaces...
November 2016: Journal of Food Protection
https://www.readbyqxmd.com/read/28221814/an-amperometric-glucose-sensor-integrated-into-an-insulin-delivery-cannula-in-vitro-and-in-vivo-evaluation
#3
W Kenneth Ward, Gabriel Heinrich, Matthew Breen, Sheila Benware, Nicole Vollum, Kristin Morris, Chad Knutsen, Joseph D Kowalski, Scott Campbell, Jerry Biehler, Mark S Vreeke, Scott M Vanderwerf, Jessica R Castle, Robert S Cargill
BACKGROUND: Labeling prohibits delivery of insulin at the site of subcutaneous continuous glucose monitoring (CGM). Integration of the sensing and insulin delivery functions into a single device would likely increase the usage of CGM in persons with type 1 diabetes. METHODS: To understand the nature of such interference, we measured glucose at the site of bolus insulin delivery in swine using a flexible electrode strip that was laminated to the outer wall of an insulin delivery cannula...
February 21, 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/28220265/similarities-and-differences-between-behavioral-and-electrophysiological-visual-acuity-thresholds-in-healthy-infants-during-the-second-half-of-the-first-year-of-life
#4
Claudia Polevoy, Gina Muckle, Jean R Séguin, Emmanuel Ouellet, Dave Saint-Amour
PURPOSE: Behavioral and electrophysiological methods for visual acuity estimation typically correlate well in children and adult populations, but this relationship remains unclear in infants, particularly during the second half of the first year of life. It has been suggested that the agreement between both methods mostly relies on age and/or subjective acuity factors. The present study aimed at comparing acuity thresholds obtained with both approaches in a sample of healthy infants in a relatively narrow age range, that is 6-10 months old...
February 20, 2017: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/28215689/histomorphometry-of-the-placental-vasculature-and-microcotyledons-in-thoroughbred-mares-with-chronic-laminitis
#5
Fernanda M Pazinato, Bruna da Rosa Curcio, Cristina G Fernandes, Carlos A Santos, Lorena S Feijó, Antonio Sérgio Varela, Carlos E W Nogueira
The objective of this study was to assess the placental vasculature and microcotyledons in pregnant mares with chronic laminitis. Twenty-six pregnant mares were enrolled in the study, 13 had chronic laminitis (Laminitis Group) and 13 were healthy mares (Healthy Group). Arterial systolic pressure and heart rate were measured in the last 30 days of gestation. After foaling, the fetal membranes were grossly evaluated and samples were harvested for histopathologic examination. All mares had digitalized images taken from chorioallantois for histomorphometry analyses (software-NIH ImageJ)...
March 15, 2017: Theriogenology
https://www.readbyqxmd.com/read/28214269/immunohistochemistry-on-a-panel-of-emery-dreifuss-muscular-dystrophy-samples-reveals-nuclear-envelope-proteins-as-inconsistent-markers-for-pathology
#6
Phu Le Thanh, Peter Meinke, Nadia Korfali, Vlastimil Srsen, Michael I Robson, Manfred Wehnert, Benedikt Schoser, Caroline A Sewry, Eric C Schirmer
Reports of aberrant distribution for some nuclear envelope proteins in cells expressing a few Emery-Dreifuss muscular dystrophy mutations raised the possibility that such protein redistribution could underlie pathology and/or be diagnostic. However, this disorder is linked to 8 different genes encoding nuclear envelope proteins, raising the question of whether a particular protein is most relevant. Therefore, myoblast/fibroblast cultures from biopsy and tissue sections from a panel of nine Emery-Dreifuss muscular dystrophy patients (4 male, 5 female) including those carrying emerin and FHL1 (X-linked) and several lamin A (autosomal dominant) mutations were stained for the proteins linked to the disorder...
December 21, 2016: Neuromuscular Disorders: NMD
https://www.readbyqxmd.com/read/28210910/astrocyte-induced-reelin-expression-drives-proliferation-of-her2-breast-cancer-metastases
#7
Rahul Jandial, Cecilia Choy, Danielle M Levy, Mike Y Chen, Khairul I Ansari
Breast cancer metastasis to the brain develops after a clinical latency of years to even decades, suggesting that colonization of the brain is the most challenging step of the metastatic cascade. However, the underlying mechanisms used by breast cancer cells to successfully colonize the brain's microenvironment remain elusive. Reelin is an archetypal extracellular glycoprotein that regulates migration, proliferation, and lamination of neurons. It is epigenetically silenced in various cancers, and its expression in multiple myelomas is linked to poor patient survival...
February 17, 2017: Clinical & Experimental Metastasis
https://www.readbyqxmd.com/read/28205600/non-reliance-of-metazoans-on-stromatolite-forming-microbial-mats-as-a-food-resource
#8
Gavin M Rishworth, Renzo Perissinotto, Matthew S Bird, Nadine A Strydom, Nasreen Peer, Nelson A F Miranda, Jacqueline L Raw
Grazing and burrowing organisms usually homogenise microalgal mats that form on benthic sediments of many aquatic ecosystems. In the absence of this disruption, microalgal mats can accrete laminated deposits (stromatolites). Stromatolites are rare in modern coastal ecosystems, but persist at locations where metazoans are largely excluded. This study aimed to assess the trophic structure at stromatolite locations where metazoans co-occur, to determine the grazing influence exerted by the metazoans on the stromatolite-forming microalgae (cyanobacteria and diatoms)...
February 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28197207/maize-fungal-growth-control-with-scopoletin-of-cassava-roots-produced-in-benin
#9
Rafiatou Ba, Teou Alfa, Fernand Gbaguidi, Kosi Mawuéna Novidzro, Kokouvi Dotse, Koffi Koudouvo, Ursula Houngue, Marcel T Donou Hounsode, Kossi Honoré Koumaglo, Yaovi Ameyapoh, Lamine Baba-Moussa
The chemical contamination of food is among the main public health issues in developing countries. With a view to find new natural bioactive products against fungi responsible for chemical contamination of staple food such as maize, the antifungal activity tests of scopoletin extracted from different components of the cassava root produced in Benin were carried out. The dosage of scopoletin from parts of the root (first skin, second skin, whole root, and flesh) was done by High Performance Liquid Chromatography...
2017: International Journal of Microbiology
https://www.readbyqxmd.com/read/28192917/simple-reagentless-quantification-of-total-bilirubin-in-blood-via-microfluidic-phototreatment-and-image-analysis
#10
Brandon L Thompson, Sarah L Wyckoff, Doris M Haverstick, James P Landers
Total bilirubin (T-Bil) is an important clinical diagnostic marker that is measured frequently by physicians to assist in the diagnosis, treatment, and monitoring of multiple medical conditions. The work demonstrated here utilizes the 48-year-old mechanism of phototherapy that is commonly implemented in the treatment of infants with exaggerated physiologic and pathologic jaundice but adapts it to the microfluidic level for the ultimate purpose of total bilirubin quantitation. After acquisition of a small volume of blood (<10 μL) and through subsequent separation (plasma + red blood cells), a 3 μL plasma sample was imaged by a portable scanner and analyzed through a custom algorithm for color intensity...
February 13, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28188704/cnot1-cooperates-with-lmna-to-aggravate-osteosarcoma-tumorigenesis-through-the-hedgehog-signaling-pathway
#11
Dong-Dong Cheng, Jing Li, Shi-Jie Li, Qing-Cheng Yang, Cun-Yi Fan
While treatments for childhood osteosarcoma have improved, the overall survival for this common type of bone cancer have not changed for three decades and thus new targets for therapeutic development are needed. To identify tumor-related proteins in osteosarcoma, we used isobaric tags in a relative and absolute quantitation (iTRAQ) proteomic approach to analyze the differentially expressed proteins between osteosarcoma cells and human osteoblastic cells. Through clinical screening and functional evaluation, CCR4-NOT transcription complex subunit 1 (CNOT1) correlated to the growth of osteosarcoma cells...
February 11, 2017: Molecular Oncology
https://www.readbyqxmd.com/read/28183127/a-redescription-of-the-long-tailed-nesokia-i-nesokia-i-i-bunnii-i-and-designation-of-a-neotype-rodentia-muridae
#12
Boris Kryštufek, Omar F Al-Sheikhly, Rainer Hutterer
Long-tailed Nesokia, Nesokia bunnii, is a large rat restricted to the Mesopotamian marshes in Basra Province in southern Iraq. The species is known from five museum vouchers collected between March 1974 and January 1977. The type and the paratype, deposited in the Natural History Research Centre and Museum, University of Baghdad, Iraq, were destroyed during War on Iraq in 2003. By studying morphological details on three museum specimens in the Senckenberg Institution, Frankfurt a. M., Germany, we show that N...
January 4, 2017: Zootaxa
https://www.readbyqxmd.com/read/28182847/preparation-and-characterization-of-an-olive-flounder-paralichthys-olivaceus-skin-gelatin-and-polylactic-acid-bilayer-film
#13
Ka-Yeon Lee, Kyung Bin Song
Olive flounder skin gelatin (OSG) was used as a film base material. A bilayer film of OSG and polylactic acid (PLA) was prepared using solvent casting method to enhance the film properties. Physical properties of the OSG-PLA film were increased compared with the nonaugmented OSG film. In particular, the PLA lamination decreased water vapor permeability from 2.17 to 0.92 × 10(-9) g·m/m(2) ·s·Pa, as well as of the water solubility from 16.62% to 9.27%, in the bilayer film relative to the OSG film. The oxygen permeability of the OSG-PLA bilayer film was held low by the OSG film, compensating for the high oxygen permeability of the PLA layer...
February 9, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28182330/heat-shock-protein-27-hsp27-hspb1-is-synthetic-lethal-to-cells-with-oncogenic-activation-of-met-egfr-and-braf
#14
John David Konda, Martina Olivero, Daniele Musiani, Simona Lamba, Maria Flavia Di Renzo
The small Heat Shock Protein of 27 KDa (HSP27) is highly expressed in many cancers and is associated with aggressive tumor behaviour, metastasis, poor prognosis and resistance to chemotherapy. We aimed at assessing the role of HSP27 in modulating responses to target therapies. We selected several oncogene-addicted cancer cell lines, which undergo either cell cycle blockade or cell death in response to agents that target the specific oncogene. Surprisingly, HSP27 suppression alone resulted in the apoptotic death of MET-addicted EBC-1 lung cancer cells, EGFR-addicted colorectal carcinoma DiFi cells and BRAF-addicted colorectal carcinoma COLO205 and OXCO-1 and melanoma COLO741 cells, all of which also undergo death when treated with the specific targeted agent...
February 9, 2017: Molecular Oncology
https://www.readbyqxmd.com/read/28179960/ternary-semitransparent-organic-solar-cells-with-a-laminated-top-electrode
#15
Mohammed Makha, Paolo Testa, Surendra Babu Anantharaman, Jakob Heier, Sandra Jenatsch, Nicolas Leclaire, Jean-Nicolas Tisserant, Anna C Véron, Lei Wang, Frank Nüesch, Roland Hany
Tinted and colour-neutral semitransparent organic photovoltaic elements are of interest for building-integrated applications in windows, on glass roofs or on facades. We demonstrate a semitransparent organic photovoltaic cell with a dry-laminated top electrode that achieves a uniform average visible transmittance of 51% and a power conversion efficiency of 3%. The photo-active material is based on a majority blend composed of a visibly absorbing donor polymer and a fullerene acceptor, to which a selective near-infrared absorbing cyanine dye is added as a minority component...
2017: Science and Technology of Advanced Materials
https://www.readbyqxmd.com/read/28174240/self-organising-aggregates-of-zebrafish-retinal-cells-for-investigating-mechanisms-of-neural-lamination
#16
Megan K Eldred, Mark Charlton-Perkins, Leila Muresan, William A Harris
To investigate the cell-cell interactions necessary for the formation of retinal layers, we cultured dissociated zebrafish retinal progenitors in agarose microwells. Within these wells, the cells re-aggregated within hours, forming tight retinal organoids. Using a Spectrum of Fates zebrafish line, in which all different types of retinal neurons show distinct fluorescent spectra, we found that by 48 hours in culture, the retinal organoids acquire a distinct spatial organization, i.e. they became coarsely but clearly laminated...
February 7, 2017: Development
https://www.readbyqxmd.com/read/28168519/pcna-is-recruited-to-irradiated-chromatin-in-late-s-phase-and-is-most-pronounced-in-g2-phase-of-the-cell-cycle
#17
Eva Bártová, Jana Suchánková, Soňa Legartová, Barbora Malyšková, Matúš Hornáček, Magdalena Skalníková, Martin Mašata, Ivan Raška, Stanislav Kozubek
DNA repair is a complex process that prevents genomic instability. Many proteins play fundamental roles in regulating the optimal repair of DNA lesions. Proliferating cell nuclear antigen (PCNA) is a key factor that initiates recombination-associated DNA synthesis after injury. Here, in very early S-phase, we show that the fluorescence intensity of mCherry-tagged PCNA after local micro-irradiation was less than the fluorescence intensity of non-irradiated mCherry-PCNA-positive replication foci. However, PCNA protein accumulated at locally irradiated chromatin in very late S-phase of the cell cycle, and this effect was more pronounced in the following G2 phase...
January 20, 2017: Protoplasma
https://www.readbyqxmd.com/read/28167603/at-home-with-mastomys-and-rattus-human-rodent-interactions-and-potential-for-primary-transmission-of-lassa-virus-in-domestic-spaces
#18
Jesse Bonwitt, Almudena Mari Sáez, Joseph Lamin, Rashid Ansumana, Michael Dawson, Jacob Buanie, Joyce Lamin, Diana Sondufu, Matthias Borchert, Foday Sahr, Elisabeth Fichet-Calvet, Hannah Brown
The multimammate mouse (Mastomys natalensis) is the reservoir for Lassa virus (LASV). Zoonotic transmission occurs when humans are directly or indirectly exposed to fluids of the multimammate mouse, such as urine, saliva, and blood. Housing characteristics and domestic organization affect rodent density in and around households and villages, and are likely to be a risk factor for Lassa fever in humans where the reservoir exists. We use semi-structured interviews (N = 51), a quantitative survey (N = 429), direct observations, and a rodent ecology study to provide new insights into how the organization of domestic spaces brings together humans and rodents and creates pathways for infection in rural settlements in Bo District, Sierra Leone...
February 6, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28167501/comprehensive-characterization-of-neutrophil-genome-topology
#19
Yina Zhu, Ke Gong, Matthew Denholtz, Vivek Chandra, Mark P Kamps, Frank Alber, Cornelis Murre
Neutrophils are responsible for the first line of defense against invading pathogens. Their nuclei are uniquely structured as multiple lobes that establish a highly constrained nuclear environment. Here we found that neutrophil differentiation was not associated with large-scale changes in the number and sizes of topologically associating domains (TADs). However, neutrophil genomes were enriched for long-range genomic interactions that spanned multiple TADs. Population-based simulation of spherical and toroid genomes revealed declining radii of gyration for neutrophil chromosomes...
February 6, 2017: Genes & Development
https://www.readbyqxmd.com/read/28165021/black-tio2-nanobelts-g-c3n4-nanosheets-laminated-heterojunctions-with-efficient-visible-light-driven-photocatalytic-performance
#20
Liyan Shen, Zipeng Xing, Jinlong Zou, Zhenzi Li, Xiaoyan Wu, Yuchi Zhang, Qi Zhu, Shilin Yang, Wei Zhou
Black TiO2 nanobelts/g-C3N4 nanosheets laminated heterojunctions (b-TiO2/g-C3N4) as visible-light-driven photocatalysts are fabricated through a simple hydrothermal-calcination process and an in-situ solid-state chemical reduction approach, followed by the mild thermal treatment (350 °C) in argon atmosphere. The prepared samples are evidently investigated by X-ray diffraction, Fourier transform infrared spectroscopy, scanning electron microscopy, transmission electron microscopy, X-ray photoelectron spectroscopy, N2 adsorption, and UV-visible diffuse reflectance spectroscopy, respectively...
February 6, 2017: Scientific Reports
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