keyword
https://read.qxmd.com/read/38537241/pre-incisional-local-infiltration-with-levobupivacaine-in-laparoscopic-cholecystectomy-a-randomized-and-clinical-trial
#1
JOURNAL ARTICLE
Jorge Herrador-Benito, Javier Páramo-Zunzunegui, Gil Rodríguez-Caravaca, Manuel Durán-Poveda
OBJECTIVE: Laparoscopic cholecystectomy (LC), despite its minimally invasive nature, requires effective control of post-operative pain. The use of local anesthetics (LA) has been studied, but the level of evidence is low, and there is little information on important parameters such as health-related quality of life (HRQoL) or return to work. The objective of the study was to evaluate the efficacy of 0.50% levobupivacaine infiltration of incisional sites in reducing POP after LC. METHODS: This was a prospective, randomized, double-blind study...
2024: Cirugia y Cirujanos
https://read.qxmd.com/read/38537236/comparison-of-perioperative-outcomes-in-obese-and-non-obese-patients-subjected-to-open-lumbar-spine-surgery
#2
JOURNAL ARTICLE
Parménides Guadarrama-Ortiz, César O Ruíz-Rivero, Deyanira Capi-Casillas, Alondra Román-Villagómez, Ulises Palacios-Zúñiga, Ángel D Prieto-Rivera, José A Choreño-Parra
OBJECTIVE: Obesity is a global epidemic affecting developing countries. The relationship between obesity and perioperative outcomes during elective lumbar spine surgery remains controversial, especially in those without morbid disease. MATERIALS AND METHODS: We retrospectively revised the medical records of patients with lumbar spine degeneration subjected to elective surgery. The data retrieved included demographic and clinical characteristics, body mass index (BMI), obesity status (BMI ≥ 30), surgical interventions, estimated blood loss (EBL), operative time, length of stay (LOS), and post-operative complications...
2024: Cirugia y Cirujanos
https://read.qxmd.com/read/38537178/-what-if-i-got-rejected-by-the-girl-i-would-rather-stop-the-pills-barriers-and-facilitators-of-adherence-to-antiretroviral-therapy-for-emerging-adults-aged-18-29-living-with-hiv-in-zimbabwe
#3
JOURNAL ARTICLE
Rebecca Jopling, Wilson Mutsvuke, Madison Fertig, Conall O'Cleirigh, Walter Mangezi, Melanie Abas
Emerging adults aged 18-29 have high rates of viral non-suppression, and poorer adherence to ART when compared to older adults. Semi-structured interviews were conducted with 24 emerging adults in Zimbabwe who had a recent history of viral non-suppression, to explore barriers and facilitators of adherence to ART. Interviews were coded using inductive thematic analysis. The mean age of participants was 23, 65% were male, and 79% reported acquiring HIV at birth. Twelve barriers to adherence were identified. Hiding HIV status due to the possible negative consequences of disclosure had a significant impact on adherence to ART...
March 27, 2024: AIDS Care
https://read.qxmd.com/read/38537158/impact-of-broadening-trial-eligibility-criteria-on-the-inclusion-of-patients-with-brain-metastases-in-cancer-clinical-trials-time-series-analyses-for-2012-2022
#4
JOURNAL ARTICLE
Hong Xiao, Riha Vaidya, Dawn L Hershman, Joseph M Unger
PURPOSE: In October 2017, an ASCO, Friends of Cancer Research (FoCR), and US Food and Drug Administration (ASCO/FoCR/FDA) task force recommended that common eligibility criteria be modified to make trials more inclusive. We examined whether patterns of exclusions regarding patients with brain metastases changed over time in relation to these recommendations. METHODS: Trial eligibility criteria were abstracted from ClinicalTrials.gov for phase I-III US-based interventional clinical trials for patients with advanced breast, colorectal, lung, or melanoma cancers from January 2012 to December 2022...
March 27, 2024: Journal of Clinical Oncology
https://read.qxmd.com/read/38537153/novel-proteomic-signatures-may-indicate-mri-assessed-intrahepatic-fat-state-and-changes-the-direct-plus-clinical-trial
#5
JOURNAL ARTICLE
Dana T Goldberg, Anat Yaskolka Meir, Gal Tsaban, Ehud Rinott, Alon Kaplan, Hila Zelicha, Nora Klöting, Uta Ceglarek, Berend Iserman, Ilan Shelef, Philip Rosen, Matthias Blüher, Michael Stumvoll, Ohad Etzion, Meir J Stampfer, Frank B Hu, Iris Shai
OBJECTIVE: We demonstrated in the randomized 18-month DIRECT PLUS trial (n=294) that a Mediterranean (MED) diet, supplemented with polyphenol-rich Mankai duckweed, green tea, and walnuts and restricted in red/processed meat, caused substantial intrahepatic fat (IHF%) loss compared with two other healthy diets, reducing NAFLD by half, regardless similar weight loss. Here, we investigated the baseline proteomic profile associated with IHF% and the changes in proteomics associated with IHF% changes induced by lifestyle intervention...
March 27, 2024: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://read.qxmd.com/read/38537149/urinary-bladder-involvement-in-igg4-related-disease-a-case-based-review
#6
JOURNAL ARTICLE
Parag Vijayvergia, Sayan Mukherjee, Lily Singh, Urmila Dhakad
Immunoglobulin G4-related disease (IgG4-RD) is an immune-driven fibroinflammatory disease that presents as tumefactive lesions that not only commonly affects the pancreas, lacrimal and salivary glands, lung, liver and kidney but can also affect any organs. However, involvement of the urinary bladder in IgG4-RD is rarely reported. We describe a case of IgG4-RD involving the urinary bladder mimicking carcinoma and review the published literature-a 39-year-old male presented with complaints of dysuria, urgency and hesitancy...
March 2, 2024: Modern rheumatology case reports
https://read.qxmd.com/read/38537128/the-impact-of-a-training-intervention-on-knowledge-confidence-and-attitudes-of-professionals-in-a-community-acquired-brain-injury-service-about-assistive-technology-for-cognition-a-before-and-after-survey
#7
JOURNAL ARTICLE
Helen MacDonald, Gemma Bradley, Katie Cummings, Gemma Eskandari, Charlotte Price, Lara Weller
Assistive Technology for Cognition (ATC) can help people to compensate for cognitive impairments following Acquired Brain Injury (ABI). Examples include mainstream devices such as smartphones, watches and environmental controls, and bespoke devices such as medication devices or specific educational software. Evidence suggests that professional support is key to people successfully adopting ATC, yet low confidence amongst clinicians and perceptions about barriers are often cited as reasons for not recommending ATC in practice...
March 27, 2024: Assistive Technology: the Official Journal of RESNA
https://read.qxmd.com/read/38537108/empowerment-moderates-the-relationship-between-partner-abuse-and-suicidal-ideation-for-immigrant-women
#8
JOURNAL ARTICLE
Sara E Butter, Bushra Sabri, Ginger C Hanson, Jacquelyn C Campbell
PURPOSE: Research shows strong associations between intimate partner violence (IPV) among women and suicidal ideation but this topic is understudied among immigrant women in abusive relationships in the United States. Empowerment may play a significant role in protecting abused immigrant women from suicidal ideation but has not been studied with quantitative data. METHOD: The current study used convenience sampling. Immigrant women who experienced IPV were asked about IPV severity, empowerment, and where they were born...
April 1, 2024: Journal of Psychosocial Nursing and Mental Health Services
https://read.qxmd.com/read/38537106/analyzing-the-relationship-between-self-efficacy-in-protecting-against-substance-use-and-loneliness-in-adolescents-a-cross-sectional-survey
#9
JOURNAL ARTICLE
Kübra Kayaoğlu, Duygu Özer
PURPOSE: To analyze the relationship between self-efficacy in protecting against substance use and loneliness in adolescents. METHOD: This descriptive, cross-sectional study comprised 400 adolescents. A Sociodemographic Data Form, Self-Efficacy for Adolescents Protecting Against Substance Abuse Scale (SEAPSAS), and Short-Form UCLA Loneliness Scale (ULS-8) were used for data collection. Regression analysis and Pearson correlation analysis, as well as descriptive statistics, were used in data analysis...
April 1, 2024: Journal of Psychosocial Nursing and Mental Health Services
https://read.qxmd.com/read/38537084/personal-versus-therapist-perioperative-music-intervention-a-randomized-controlled-trial
#10
JOURNAL ARTICLE
Fan Jiang, Tingting Wang, Liqiong Hu, Shangui Chen, Lijian Chen, Xuesheng Liu, Yao Lu, Erwei Gu, Luis Ulloa
INTRODUCTION: Music interventions can alleviate patient anxiety and improve post-surgical satisfaction. However, it remains uncertain whether music personal preferences affect efficacy. We tested whether personal music intervention with patient-selected songs played ad libitum is more effective than standard therapist-designed treatment with classical music. METHODS: A prospective, parallel-group, single-blinded, randomized controlled trial with 229 participants (aged 18 to 60 y) previously scheduled for elective surgery...
April 3, 2024: International Journal of Surgery
https://read.qxmd.com/read/38537081/performance-of-outbreak-management-plans-for-emerging-plant-diseases-the-case-of-almond-leaf-scorch-caused-by-xylella-fastidiosa-in-mainland-spain
#11
JOURNAL ARTICLE
Martina Cendoya, Elena Lázaro, Ana Navarro-Quiles, Antonio López-Quílez, David Conesa, Antonio Vicent
Outbreak response to quarantine pathogens and pests in the European Union (EU) is regulated by the EU Plant Health Law, but the performance of outbreak management plans in terms of their effectiveness and efficiency has been quantified only to a limited extent. As a case study, the disease dynamics of almond leaf scorch, caused by Xylella fastidiosa ( Xf ), in the affected area of Alicante, Spain, were approximated using an individual-based spatial epidemiological model. The emergence of this outbreak was dated based on phylogenetic studies, and official surveys were used to delimit the current extent of the disease...
March 27, 2024: Phytopathology
https://read.qxmd.com/read/38537068/fear-of-recurrence-among-lung-cancer-survivors-a-theoretical-model-validation
#12
JOURNAL ARTICLE
Qiuhong Chen, Yunqin Weng, Fangfang Wang, Xiaoyan Yang, Wei-Ti Chen, Feifei Huang
BACKGROUND: Fear of cancer recurrence (FCR) significantly impacts the treatment and prognosis of lung cancer survivors. However, the mechanisms and factors contributing to FCR and its related consequences in lung cancer remain poorly understood. OBJECTIVE: To evaluate the validity of the Lee-Jones Theoretical Model of FCR in lung cancer survivors. METHODS: A cross-sectional survey was conducted among 257 lung cancer survivors who had undergone surgical treatment 1 year prior...
March 27, 2024: Cancer Nursing
https://read.qxmd.com/read/38537063/impella-as-bridge-to-durable-left-ventricular-assist-device-in-acute-myocardial-infarction-cardiogenic-shock-patients
#13
JOURNAL ARTICLE
Silvia Ajello, Marina Pieri, Sara Dormio, Luca Baldetti, Savino Altizio, Filippo Consolo, Pasquale Nardelli, Alessandro Ortalda, Anna Mara Scandroglio
Implantation of durable left ventricular assist device (LVAD) in cardiogenic shock (CS) patients after acute myocardial infarction (AMI) poses specific challenges (small left ventricular size, acute infarct area, need for antithrombotic therapy, status Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) 1 with impaired organ function and derangements in coagulation and inflammatory parameters) which may affect outcomes. We reviewed data of all AMI-CS patients who were implanted LVAD after Impella support at a referral center with the aim to analyze feasibility, timing, and outcomes of durable LVAD implantation after tMCS with Impella due to AMI-CS...
March 28, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://read.qxmd.com/read/38537051/forecasting-the-effect-of-hiv-targeted-interventions-on-the-age-distribution-of-people-living-with-hiv-a-case-study-from-kenya
#14
JOURNAL ARTICLE
Melissa C Schnure, Parastu Kasaie, David W Dowdy, Becky L Genberg, Emily A Kendall, Anthony T Fojo
OBJECTIVES: Expansion of ART and increases to life expectancy have led to aging among people living with HIV (PWH). DESIGN: Kenyan decisionmakers need accurate forecasts of the age distribution of PWH to inform future policies. METHODS: We developed a model of HIV in Kenya, calibrated to historical estimates of HIV epidemiology. We forecasted changes in population size and age distribution of new HIV infections and PWH under the status quo and under scale-up of HIV services...
March 27, 2024: AIDS
https://read.qxmd.com/read/38537027/home-vs-gym-based-exercise-delivery-modes-of-two-multicomponent-intensity-training-regimes-on-cardiorespiratory-fitness-and-arterial-stiffness-in-adults-with-intellectual-and-developmental-disability-during-the-covid-19-pandemic-a-randomized-controlled-trial
#15
JOURNAL ARTICLE
Xavier Melo, Bruno Simão, Catarina Catela, Isabel Oliveira, Sara Planche, Ana Louseiro, João Luís Marôco, Guillermo R Oviedo, Bo Fernhall, Helena Santa-Clara
Background: We compared the effects of home- vs gym-based delivery modes of two 8-week supervised multicomponent intensity training regimes on cardiorespiratory fitness and arterial stiffness in 17 adults with intellectual and developmental disability during the COVID-19 pandemic. Methods : Participants were assigned to sprint interval training or continuous aerobic training, both incorporating resistance training. The intervention started with 8-weeks of online training (M1-M2), 1-month of detraining, plus 8-weeks of gym-based training (M3-M4)...
March 27, 2024: Journal of Intellectual Disabilities: JOID
https://read.qxmd.com/read/38537025/effects-of-an-early-intensive-blood-pressure-lowering-strategy-using-remifentanil-and-dexmedetomidine-in-patients-with-spontaneous-intracerebral-hemorrhage-a-multicenter-prospective-superiority-randomized-controlled-trial
#16
JOURNAL ARTICLE
Rui Dong, Fen Li, Bin Li, Qiming Chen, Xianjian Huang, Jiehua Zhang, Qibing Huang, Zeli Zhang, Yunxing Cao, Mingbiao Yang, Jianwei Li, Zhanfu Li, Cuiyu Li, Guohua Liu, Shu Zhong, Guang Feng, Ming Zhang, Yumei Xiao, Kangyue Lin, Yunlong Shen, Huanzhang Shao, Yuan Shi, Xiangyou Yu, Xiaopeng Li, Lan Yao, Xinyu Du, Ying Xu, Pei Kang, Guoyi Gao, Bin Ouyang, Wenjin Chen, Zhenhua Zeng, Pingyan Chen, Chunbo Chen, Hong Yang
BACKGROUND: Although it has been established that elevated blood pressure and its variability worsen outcomes in spontaneous intracerebral hemorrhage, antihypertensives use during the acute phase still lacks robust evidence. A blood pressure-lowering regimen using remifentanil and dexmedetomidine might be a reasonable therapeutic option given their analgesic and anti-sympathetic effects. The objective of this superiority trial was to validate the efficacy and safety of this blood pressure-lowering strategy that uses remifentanil and dexmedetomidine in patients with acute intracerebral hemorrhage...
March 27, 2024: Anesthesiology
https://read.qxmd.com/read/38536990/self-perception-of-mental-health-covid-19-and-associated-sociodemographic-contextual-factors-in-latin-america
#17
JOURNAL ARTICLE
Pablo Roa, Guillermo Rosas, Gloria Isabel Niño-Cruz, Sergio Mauricio Moreno-López, Juliana Mejía-Grueso, Haney Aguirre-Loaiza, Javiera Alarcón-Aguilar, Rodrigo Reis, Adriano Akira Ferreira Hino, Fernando López, Deborah Salvo, Andrea Ramírez-Varela
This study aimed to estimate the prevalence of alterations in self-perceived mental health during the COVID-19 pandemic and their associated factors in four Latin American countries. This is a cross-sectional study based on data collected from adults in 2021 through the Collaborative Response COVID-19 Survey by the MacDonnell Academy at Washington University in St. Louis (United States). The sample was composed of 8,125 individuals from Brazil, Colombia, Mexico, and Chile. A generalized linear model for a binary outcome variable with a logistic link and fixed country effects was used...
2024: Cadernos de Saúde Pública
https://read.qxmd.com/read/38536983/clinical-outcomes-before-and-after-videofluoroscopic-swallow-study-in-children-24-months-of-age-or-younger
#18
JOURNAL ARTICLE
Fabiola Luciane Barth, Deborah Salle Levy, Marisa Gasparin, Cláudia Schweiger, Denise Manica, Camila Dalbosco Gadenz, Paulo José Cauduro Maróstica
OBJECTIVE: To evaluate the combined impact of videofluoroscopic swallow study (VFSS) and therapeutic feeding and swallowing interventions on clinical outcomes in children with oropharyngeal dysphagia (OPD). METHODS: This was an uncontrolled longitudinal analytical study in which OPD patients were evaluated before and after VFSS. Children ≤ 24 months of age diagnosed with OPD in a clinical setting and undergoing VFSS for investigation and management of OPD were included in the study...
2024: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://read.qxmd.com/read/38536971/quality-of-life-of-women-who-underwent-breast-cancer-treatment-relative-to-sociodemographic-behavioral-and-clinical-factors
#19
JOURNAL ARTICLE
Angélica Atala Lombelo Campos, Maria Teresa Bustamante-Teixeira, Rafaela Russi Ervilha, Vivian Assis Fayer, Jane Rocha Duarte Cintra, Renata Mendes de Freitas, Daniela Pereira de Almeida, Maximiliano Ribeiro Guerra
OBJECTIVE: Patients with cancer often undergo multiple extended treatments that decrease their quality of life. However, the quality of life of women with breast cancer after they undergo treatment remains underexplored in Brazil. Therefore, this study determined sociodemographic, behavioral, and clinical factors related to the post-treatment quality of life of women with breast cancer. METHODS: This cross-sectional study involved 101 women diagnosed with breast cancer between 2014 and 2016 and treated at a Brazilian Oncology Reference Service...
2024: Einstein
https://read.qxmd.com/read/38536964/lessons-from-insulin-policy-prescriptions-for-affordable-diabetes-and-obesity-medications
#20
REVIEW
Kathryn E Nagel, Reshma Ramachandran, Kasia J Lipska
Escalating insulin prices have prompted public scrutiny of the practices of drug manufacturers, pharmacy benefit managers, health insurers, and pharmacies involved in production and distribution of medications. As a result, a series of policies have been proposed or enacted to improve insulin affordability and foster greater equity in access. These policies have implications for other diabetes and obesity therapeutics. Recent legislation, at both the state and federal level, has capped insulin out-of-pocket payments for some patients...
March 27, 2024: Diabetes Care
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