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https://www.readbyqxmd.com/read/28645015/mid-infrared-and-near-infrared-spectroscopy-for-rapid-detection-of-gardeniae-fructus-by-a-liquid-liquid-extraction-process
#1
Lingyan Tao, Zhonglin Lin, Jiashan Chen, Yongjiang Wu, Xuesong Liu
Gardeniae Fructus is widely used in the pharmaceutical industry, and many studies have confirmed its medical and economic value. In this study, samples collected from different liquid-liquid extraction batches of Gardeniae Fructus were detected by mid-infrared (MIR) and near-infrared (NIR) spectroscopy. Seven analytes, neochlorogenic acid (5-CQA), cryptochlorogenic acid (4-CQA), chlorogenic acid (3-CQA), geniposidic acid (GEA), deacetyl-asperulosidic acid methyl ester (DAAME), genipin-gentiobioside (GGB), and gardenoside (GA), were chosen as quality property indexes of Gardeniae Fructus...
June 16, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28644290/could-emotional-intelligence-make-patients-safer
#2
Estelle Codier, David D Codier
: The vast majority of medical errors occurring each year involve faulty communication. For this reason, it's essential that we identify skills that support accurate communication and information transfer as well as optimum patient-centered care, team function, and patient safety. Research in nursing and other disciplines has demonstrated that emotional intelligence abilities improve communication, support constructive conflict resolution, and improve individual and team performance. Although further studies are needed, these findings suggest emotional intelligence ability can positively affect patient safety...
July 2017: American Journal of Nursing
https://www.readbyqxmd.com/read/28643113/-safety-culture-in-orthopedics-and-trauma-surgery-course-concept-interpersonal-competence-by-the-german-society-for-orthopaedics-and-trauma-dgou-and-lufthansa-aviation-training
#3
REVIEW
A-K Doepfer, R Seemann, D Merschin, R Stange, M Egerth, M Münzberg, M Mutschler, B Bouillon, R Hoffmann
Patient safety has become a central and measurable key factor in the routine daily medical practice. The human factor plays a decisive role in safety culture and has moved into focus regarding the reduction of treatment errors and undesired critical incidents. Nonetheless, the systematic training in communication and interpersonal competences has so far only played a minor role. The German Society of Orthopaedics and Trauma (DGOU) in cooperation with the Lufthansa Aviation Training initiated a course system for interpersonal competence...
June 22, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/28643059/the-learning-effect-of-using-stereoscopic-vision-in-the-early-phase-of-laparoscopic-surgical-training-for-novices
#4
Hitoshi Harada, Shingo Kanaji, Masayasu Nishi, Yoshito Otake, Hiroshi Hasegawa, Masashi Yamamoto, Yoshiko Matsuda, Kimihiro Yamashita, Takeru Matsuda, Taro Oshikiri, Yasuo Sumi, Tetsu Nakamura, Satoshi Suzuki, Yoshinobu Sato, Yoshihiro Kakeji
BACKGROUND: Recently to improve depth perception, the performance of three-dimensional (3D) laparoscopic surgeries has increased. However, the effects of laparoscopic training using 3D are still unclear. This study aimed to clarify the effects of using a 3D monitor among novices in the early phase of training. METHODS: Participants were 40 novices who had never performed laparoscopic surgery (20 medical students and 20 junior residents). Three laparoscopic phantom tasks (task 1: touching markers on a flat disk with a rod; task 2: straight rod transfer through a single loop; and task 3: curved rod transfer through two loops) in the training box were performed ten times, respectively...
June 22, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28643030/hospital-electronic-prescribing-system-implementation-impact-on-discharge-information-communication-and-prescribing-errors-a-before-and-after-study
#5
Pamela Ruth Mills, Anita Elaine Weidmann, Derek Stewart
PURPOSE: The study aimed to test the hypothesis that hospital electronic prescribing and medicine administration system (HEPMA) implementation impacted patient discharge letter quality, nature and frequency of prescribing errors. METHOD: A quasi experimental before and after retrospective case note review was conducted in one United Kingdom district general hospital. The total sample size was 318 (random samples of 159 before and after implementation), calculated to achieve a 10% error reduction with a power of 80% and p < 0...
June 22, 2017: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28643024/automatic-seed-picking-for-brachytherapy-postimplant-validation-with-3d-ct-images
#6
Guobin Zhang, Qiyuan Sun, Shan Jiang, Zhiyong Yang, Xiaodong Ma, Haisong Jiang
PURPOSE: Postimplant validation is an indispensable part in the brachytherapy technique. It provides the necessary feedback to ensure the quality of operation. The ability to pick implanted seed relates directly to the accuracy of validation. To address it, an automatic approach is proposed for picking implanted brachytherapy seeds in 3D CT images. METHODS: In order to pick seed configuration (location and orientation) efficiently, the approach starts with the segmentation of seed from CT images using a thresholding filter which based on gray-level histogram...
June 22, 2017: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/28642027/-monitoring-devices-and-their-alarms-incident-reports-suggest-problems-with-device-knowledge
#7
Kathrin Lange, Miriam Nowak, Claudia Neudörfl, Wolfgang Lauer
Missing or false device alarms pose a risk in clinical practice. Publications from the United States suggest that alarm errors are not only caused by technical issues but to a considerable degree result from user-device interaction problems. To safely operate a medical device, users have to thoroughly understand both device behavior and device functioning. They also need to foresee the exact consequences of their interactions with the device. This can be challenging, especially if a device has multiple functions, is applied in various use contexts or networked with other devices - as is often the case with patient monitors...
June 19, 2017: Zeitschrift Für Evidenz, Fortbildung und Qualität Im Gesundheitswesen
https://www.readbyqxmd.com/read/28641925/safety-pharmacokinetics-and-sialic-acid-production-after-oral-administration-of-n-acetylmannosamine-mannac-to-subjects-with-gne-myopathy
#8
Xin Xu, Amy Q Wang, Lea L Latham, Frank Celeste, Carla Ciccone, May Christine Malicdan, Barry Goldspiel, Pramod Terse, James Cradock, Nora Yang, Selwyn Yorke, John C McKew, William A Gahl, Marjan Huizing, Nuria Carrillo
GNE myopathy is a rare, autosomal recessive, inborn error of sialic acid metabolism, caused by mutations in GNE, the gene encoding UDP-N-acetyl-glucosamine-2-epimerase/N-acetylmannosamine kinase. The disease manifests as an adult-onset myopathy characterized by progressive skeletal muscle weakness and atrophy. There is no medical therapy available for this debilitating disease. Hyposialylation of muscle glycoproteins likely contributes to the pathophysiology of this disease. N-acetyl-D-mannosamine (ManNAc), an uncharged monosaccharide and the first committed precursor in the sialic acid biosynthetic pathway, is a therapeutic candidate that prevents muscle weakness in the mouse model of GNE myopathy...
April 26, 2017: Molecular Genetics and Metabolism
https://www.readbyqxmd.com/read/28641666/-rare-blood-group-and-its-progress-of-research-in-transfusion-medicine-review
#9
Qing-Sheng Cao, Tao Yang, Ming-Hui Wang
As one of key factors for transfusion reaction, rare blood group has attached lots of attention for a long time. The proportion of the people population with rare blood group is actually low, however, the improper disposition caused by human error always leads to severe medical accident, showing its undoubted importance in transfusion medicine. Recently, more research about rare blood group are reported. Therefore, this review summarizes the development of this aspect, including mainly rare blood group, the detection of blood group phenotype, and the way of transfusion for rare blood group...
June 2017: Zhongguo Shi Yan Xue Ye Xue za Zhi
https://www.readbyqxmd.com/read/28641248/method-for-simulating-dose-reduction-in-digital-breast-tomosynthesis
#10
Lucas R Borges, Igor Guerrero, Predrag R Bakic, Alessandro Foi, Andrew D A Maidment, Marcelo A C Vieira
This work proposes a new method of simulating dose reduction in digital breast tomosynthesis (DBT), starting from a clinical image acquired with a standard radiation dose. It considers both signal-dependent quantum and signal-independent electronic noise. Furthermore, the method accounts for pixel crosstalk, which causes the noise to be frequency-dependent, thus increasing the simulation accuracy. For an objective assessment, simulated and real images were compared in terms of noise standard deviation, signal-to-noise ratio (SNR) and normalized noise power spectrum (NNPS)...
June 15, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28641160/effects-of-hip-joint-centre-mislocation-on-gait-kinematics-of-children-with-cerebral-palsy-calculated-using-patient-specific-direct-and-inverse-kinematic-models
#11
Hans Kainz, Christopher P Carty, Sheanna Maine, Henry P J Walsh, David G Lloyd, Luca Modenese
Joint kinematics can be calculated by Direct Kinematics (DK), which is used in most clinical gait laboratories, or Inverse Kinematics (IK), which is mainly used for musculoskeletal research. In both approaches, joint centre locations are required to compute joint angles. The hip joint centre (HJC) in DK models can be estimated using predictive or functional methods, while in IK models can be obtained by scaling generic models. The aim of the current study was to systematically investigate the impact of HJC location errors on lower limb joint kinematics of a clinical population using DK and IK approaches...
June 4, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28640946/physicians-non-uniform-approach-to-prescribing-drugs-to-older-patients-a-qualitative-study
#12
Line Due Christensen, Janne Petersen, Ove Andersen, Susanne Kaae
Multi-morbidity and polypharmacy are common in older patients and increase their susceptibility to adverse drug events and hospitalizations. Rational drug prescription is critical, however, little is known about physicians' perspectives on how to prescribe drugs for older patients. The aim of this study was to explore physicians' approach to prescribe drugs to older patients, including identifying the drugs that physicians perceive to be risk drugs for older patients and comparing them with established lists of potentially inappropriate medications...
June 22, 2017: Basic & Clinical Pharmacology & Toxicology
https://www.readbyqxmd.com/read/28638892/in-vivo-effect-of-guiding-herb-radix-platycodonis-and-radix-cyathulae-on-paeoniflorin-pharmacokinetics-of-xuefu-zhuyu-tang-in-rats
#13
Song-Qi Tang, Yun-Hui Chen, Xi-Ping Chen, Xiao-Dan Zhang, Wei Huang
BACKGROUND: Xuefu Zhuyu Tang (XFZYT), first recorded in Correction of Errors in Medical Works by Qing-ren Wang, has been proven reliable and effective for curing various diseases such as atherosclerosis, hypertension, hyperlipidemia, and angina pectoris. It consists of 11 herbs and two of them, Radix platycodonis and Radix cyathulae, have been traditionally considered as guiding herbs and deeply valued by tens of millions of Chinese medicine practitioners. Do Radix platycodonis and Radix cyathulae affect the pharmacokinetics of the effective constituent-paeoniflorin of XFZYT? If yes, in what way? This study aims to answer these questions...
2017: African Journal of Traditional, Complementary, and Alternative Medicines: AJTCAM
https://www.readbyqxmd.com/read/28638813/impractical-cme-programs-influential-parameters-in-iran
#14
Seyed Aliakbar Faghihi, Hamid Reza Khankeh, Seyed Jalil Hosseini, Seyed Kamran Soltani Arabshahi, Zahra Faghih, Mandana Shirazi
Background: Traditional approaches in Continuing Medical Education (CME) appear to be ineffective in any improvement of the patients' care, reducing the medical errors, and/or altering physicians' behaviors. However, they are still executed by the CME providers, and are popular among the majority of the physicians. In this study, we aimed to explore the parameters involved in the degree of effectiveness of CME program in Iran. Methods: In this study, 31 participants, consisting of general practitioners, CME experts and providers were recruited to participate in in-depth interviews and field observations concerning experiences with CME...
2017: Medical Journal of the Islamic Republic of Iran
https://www.readbyqxmd.com/read/28638507/the-impact-of-using-mean-versus-mode-when-assessing-resident-competency
#15
Patrick B Barlow, Kate DuChene Thoma, Kristi J Ferguson
BACKGROUND: The Accreditation Council for Graduate Medical Education Milestone Project was implemented in 2014 to standardize assessments and progression of residents. While it is recommended that milestones not be used as tools for direct assessments of resident competency, many programs have used or adapted milestone tools for this purpose. OBJECTIVE: We sought to explore use of the most frequent milestone level at which a resident was evaluated (ie, the mode), and compared this to the standard practice of using the arithmetic mean for summarizing performance...
June 2017: Journal of Graduate Medical Education
https://www.readbyqxmd.com/read/28637358/comparative-simulation-study-of-glucose-control-methods-designed-for-use-in-the-intensive-care-unit-setting-via-a-novel-controller-scoring-metric
#16
Jeremy DeJournett, Leon DeJournett
BACKGROUND: Effective glucose control in the intensive care unit (ICU) setting has the potential to decrease morbidity and mortality rates and thereby decrease health care expenditures. To evaluate what constitutes effective glucose control, typically several metrics are reported, including time in range, time in mild and severe hypoglycemia, coefficient of variation, and others. To date, there is no one metric that combines all of these individual metrics to give a number indicative of overall performance...
June 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/28635869/-the-topical-problems-of-expert-mistakes-and-evaluation-of-the-quality-of-forensic-medical-expertises-based-on-the-analysis-of-the-reports-published-in-the-journal-sudebno-meditsinskaya-ekspertiza-forensic-medical-expertise-during-the-period-from-1958-till
#17
L A Shmarov
The objective of the present study was the thematic analysis of the reports published in the journal 'Sudebno-meditsinskaya ekspertiza' (Forensic Medical Expertise) during the period from 1958 till 2015 that contain the authors' characteristics of the mistakes made in connection with the performance of various forms of forensic medical expertise with special reference to their quality and time schedules. A total of 268 issues of the journal were looked through from which 25 articles were selected dealing with the analysis of expert mistakes...
2017: Sudebno-meditsinskaia Ekspertiza
https://www.readbyqxmd.com/read/28635574/-it-is-all-about-the-form-adrenaline-in-anaphylaxis-intravenous-or-intramuscular-administration
#18
M van der Have, D Dekker, E M J Theunissen, C Snijders, K A H Kaasjager
BACKGROUND: Medication errors are a frequent problem in the accident and emergency (A&E) department. CASE DESCRIPTION: A 17-year-old boy was referred to our A&E department with an anaphylactic reaction to peanuts. Because of various shortcomings in the care process in A&E, adrenaline was administered intravenously instead of intramuscularly, resulting in a broad complex tachycardia. We analysed these shortcomings using the 'Prevention and recovery information system for monitoring and analysis' (PRISMA) method...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/28633732/to-err-is-human-can-american-medicine-learn-from-past-mistakes
#19
Jeffrey B Ritterman
The history of medicine includes many errors. Some persisted for decades and caused great harm. Several are highlighted in this article, including the mythical thymic diseases: thymic asthma and status thymicolymphaticus. Some medical mistakes, such as the diet-heart hypothesis of Ancel Keys, continue to cause harm. To avoid future errors and their associated harm, I suggest a cultural shift encouraging professional humility and greater questioning of medical dogma. Medical education focused on teaching students this history may help with this cultural shift...
2017: Permanente Journal
https://www.readbyqxmd.com/read/28633460/guidelines-for-composing-and-assessing-a-paper-on-treatment-of-pain
#20
Nikolai Bogduk, David J Kennedy, Yakov Vorobeychik, Andrew Engel
Authors, readers, and editors share a common focus. Authors want to publish their work. Readers want to see high-quality, new information. Referees and editors serve to ensure that authors provide valid conclusions based on the quality of information that readers want. Common to each of these roles are instructions to authors. However, these are typically written in an uninspiring, legalistic style, as if they are a set of rules that authors must obey if they expect to get published. This renders the instructions boring and oppressive, if not forbidding...
June 17, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
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