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medication error

S Benacchio, O Doutres, A Le Troter, A Varoquaux, E Wagnac, V Callot, F Sgard
Passive and active in-ear devices (IED) occluding the ear canal are commonly used to (i) protect people from high noise levels (earplugs), (ii) assist people suffering from hearing impairment (hearing aids) or (iii) help people in listening from their sound systems (earbuds). However, the usability and/or efficiency of IEDs can be greatly affected by several discomfort components (physical, acoustical and functional). The mechanical pressure exerted by the IED onto the ear canal walls is greatly suspected to affect the aforementioned comfort components...
June 2, 2018: Hearing Research
Michael A Noble, Robert Rennie
BACKGROUND: Reporting on the presence of antimicrobial resistance is of considerable concern both for individual patient care and for understanding the underlying health status within the community at large. Antimicrobial resistance is solely dependent upon clinical laboratory detection and thus can be impacted upon by the quality and competence of medical laboratories. Proficiency testing or external quality assessment (PT/EQA) is the international standard for the direct measurement of medical laboratory performance on critical testing...
June 15, 2018: Diagnosis
Giuseppe Agapito, Pietro Hiram Guzzi, Mario Cannataro
Personalized medicine is an aspect of the P4 medicine (predictive, preventive, personalized and participatory) based precisely on the customization of all medical characters of each subject. In personalized medicine, the development of medical treatments and drugs is tailored to the individual characteristics and needs of each subject, according to the study of diseases at different scales from genotype to phenotype scale. To make concrete the goal of personalized medicine, it is necessary to employ high-throughput methodologies such as Next Generation Sequencing (NGS), Genome-Wide Association Studies (GWAS), Mass Spectrometry or Microarrays, that are able to investigate a single disease from a broader perspective...
June 14, 2018: High-throughput
Virginie Moulin, Francesco Grandoni, Julien Castioni, Henri Lu
Thiamine-responsive megaloblastic anaemia (TRMA) is a syndrome associated with megaloblastic anaemia, diabetes mellitus and sensorineural deafness, due to mutations in the SLC19A2 gene, which codes for a thiamine carrier protein. Oral thiamine supplementation is the main treatment. We report the case of a 25-year-old woman known for TRMA, who presented with pancytopenia (haemoglobin 7.6 g/dL, leucocytes 2.9×109 /L, thrombocytes 6×109 /L) revealed by dyspnoea. Investigations excluded coagulopathy, a recent viral infection, vitamin and iron deficiencies, and a malignant process...
June 14, 2018: BMJ Case Reports
Jennifer VanderWeele, Teresa Pollack, Diana Johnson Oakes, Colleen Smyrniotis, Vidhya Illuri, Priyathama Vellanki, Kevin O'Leary, Jane Holl, Grazia Aleppo, Mark E Molitch, Amisha Wallia
AIMS: This study validated enterprise data warehouse (EDW) data for a cohort of hospitalized patients with a primary diagnosis of diabetic ketoacidosis (DKA). METHODS: 247 patients with 319 admissions for DKA (ICD-9 code 250.12, 250.13, or 250.xx with biochemical criteria for DKA) were admitted to Northwestern Memorial Hospital from 1/1/2010 to 9/1/2013. Validation was performed by electronic medical record (EMR) review of 10% of admissions (N = 32). Classification of diabetes type (Type 1 vs...
May 8, 2018: Journal of Diabetes and its Complications
Rima Abdul Razzak, Abdulla Faisal Alshaiji, Abdulrahman Ahmed Qareeballa, Mohamed Wael Mohamed, Jeff Bagust, Sharon Docherty
The negative effects of high normal glucose on cognitive function were previously reported in euglycemic individuals of middle age and the elderly population. This study aimed at examining the effect of baseline blood glucose levels on spatial ability, specifically verticality perception on the computerized rod and frame test (CRFT) in young healthy adults. 63 healthy male medical students (age range from 18-23 years), of whom 30 were non-fasting outside the month of Ramadan and 33 fasting during Ramadan of the year 2016, were recruited in order to create varying degrees of glycemia during which verticality perception was carried out...
2018: PloS One
Minsu Ock, Eun Young Choi, Min-Woo Jo, Sang-Il Lee
To introduce disclosure of patient safety incidents (DPSI) into a specific country, evidence of the effectiveness of DPSI is essential. Since such a disclosure policy has not been adopted in South Korea, hypothetical cases can be used to measure the effectiveness of DPSI. We evaluated the effectiveness of DPSI using hypothetical cases in a survey with a sample of the Korean general public. We used 8 hypothetical cases reflecting 3 conditions: the clarity of medical errors, the severity of harm, and conducting DPSI...
2018: PloS One
Hongzhe Dou, Yuejia Zhao, Yanhong Chen, Qingchun Zhao, Bo Xiao, Yan Wang, Yonghe Zhang, Zhiguo Chen, Jie Guo, Lingwei Tao
BACKGROUND: Haze leads to many direct serious public health impacts. Understanding haze related knowledge can not only help adolescents organize health protection awareness to prevent the harmful effects that haze has on the body, but also promote their normal growth and development. METHODS: By considering, as the theoretical basis, the reasons behind the formation of haze and the underlying mechanisms of the diseases that it causes, in addition to also investigating extensive literature references, our research team developed the Adolescent Haze Related Knowledge Awareness Assessment Scale (AHRKAAS-I)...
June 14, 2018: BMC Public Health
Aditya P Apte, Aditi Iyer, Mireia Crispin-Ortuzar, Rutu Pandya, Lisanne V van Dijk, Emiliano Spezi, Maria Thor, Hyemin Um, Harini Veeraraghavan, Jung Hun Oh, Amita Shukla-Dave, Joseph O Deasy
PURPOSE: Radiomics is a growing field of image quantification, but it lacks stable and high-quality software systems. We extended the capabilities of the Computational Environment for Radiological Research (CERR) to create a comprehensive, open-source, MATLAB-based software platform with an emphasis on reproducibility, speed, and clinical integration of radiomics research. METHOD: The radiomics tools in CERR were designed specifically to quantify medical images in combination with CERR's core functionalities of radiological data import, transformation, management, image segmentation, and visualization...
June 13, 2018: Medical Physics
Waleed Alharbi, Jennifer Cleland, Zoe Morrison
Objectives: We sought to evaluate patient safety culture across different healthcare professionals from different countries of origin working in an adult oncology department in a medical facility in Saudi Arabia. Methods: This cross-sectional survey of 130 healthcare staff (doctors, pharmacists, nurses) was conducted in February 2017. We used the Hospital Survey of Patient Safety Culture (HSOPSC) to examine healthcare staff perceptions of safety culture. Results: A total of 127 questionnaires were returned, yielding a response rate of 97...
May 2018: Oman Medical Journal
William Alexander, George Miller, Preeya Alexander, Michael A Henderson, Angela Webb
BACKGROUND: Skin cancers are extremely common and the incidence increases with age. Care for patients with multiple or complicated skin cancers often require multidisciplinary input involving a general practitioner, dermatologist, plastic surgeon and/or radiation oncologist. Timely, efficient care of these patients relies on precise and effective communication between all parties. Until now, descriptions regarding the location of lesions on the scalp have been inaccurate, which can lead to error with the incorrect lesion being excised or biopsied...
June 12, 2018: ANZ Journal of Surgery
Minsu Ock, Min-Woo Jo, Eun Young Choi, Sang-Il Lee
OBJECTIVES: Previous studies have demonstrated that the general public can report various patient safety incidents (PSIs) that are not identified by other methods. In this study, we investigated the characteristics of PSIs that the general public experience in Korea. METHODS: In face-to-face surveys, participants were asked to report the frequency and type of PSIs, level of patient harm, and whether the PSIs were perceived as a medical error. We conducted logistic regression analysis to identify the sociodemographic factors of participants associated with their PSI experiences...
June 11, 2018: Journal of Patient Safety
Shih-Chieh Shao, Edward Chia-Cheng Lai, Kok Loon Owang, Hui-Yu Chen, Yuk-Ying Chan
Medication errors substantially threaten patient safety, and their prevention requires clinical vigilance. We present a case of taking the wrong drug due to a dispensing error by pharmacists involving medication packaging confusion, and we report how we prevent similar dispensing errors by thorough investigation and intervention. This case emphasizes the need for constant attention by hospital, medical industry, and regulatory authorities to avoid look-alike medication packaging in the interest of medication safety...
June 11, 2018: Journal of Patient Safety
Jyotindra Narayan, Ekta Singla, Sanjeev Soni, Ashish Singla
Over the last few decades, medical-assisted robots have been considered by many researchers, within the research domain of robotics. In this article, a 5-degrees-of-freedom spatial medical manipulator is analyzed for path planning, based on inverse kinematic solutions. Analytical methods have generally employed for finding the inverse kinematic solutions in earlier studies. However, this method is only appreciable in case of closed-form solutions. The unusual joint configurations of considered manipulator result in more complexity to attain the closed-form solutions, analytically...
June 1, 2018: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
Elisa Martín-Merino, Amaia Calderón-Larrañaga, Samuel Hawley, Beatriz Poblador-Plou, Ana Llorente-García, Irene Petersen, Daniel Prieto-Alhambra
Background: Missing data are often an issue in electronic medical records (EMRs) research. However, there are many ways that people deal with missing data in drug safety studies. Aim: To compare the risk estimates resulting from different strategies for the handling of missing data in the study of venous thromboembolism (VTE) risk associated with antiosteoporotic medications (AOM). Methods: New users of AOM (alendronic acid, other bisphosphonates, strontium ranelate, selective estrogen receptor modulators, teriparatide, or denosumab) aged ≥50 years during 1998-2014 were identified in two Spanish (the Base de datos para la Investigación Farmacoepidemiológica en Atención Primaria [BIFAP] and EpiChron cohort) and one UK (Clinical Practice Research Datalink [CPRD]) EMR...
2018: Clinical Epidemiology
Vasudha Kemmanu, Subramanya K Giliyar, Bhujanga K Shetty, Arvind Kumar Singh, Govindasamy Kumaramanickavel, Catherine A McCarty
AIM: To discuss the aims, methods, and results of a population-based cross-sectional prevalence survey of children ≤15 years, in South India and compare it with a study conducted earlier, in the same area. We also discuss the changing trends in the domain of childhood blindness in India. METHODS: A population-based cross-sectional prevalence survey of children ≤15 years, in Pavagada and Madhugiri taluks of Tumkur district in Karnataka state in south India, was conducted in 2 phases...
June 11, 2018: Eye
Cheng-Chung Lin, Jia-Da Li, Tung-Wu Lu, Mei-Ying Kuo, Chien-Chun Kuo, Horng-Chuang Hsu
PURPOSES: To propose a new model-based tracking method for measuring 3-D dynamic joint kinematics using a clinical alternating biplane x-ray imaging system; and to quantify in vitro its errors in measuring ankle and knee motions at different motion speeds. METHODS: A new model-based tracking method based on motion component partition and interpolation (MCPI) was developed for measuring 3-D dynamic joint kinematics based on a clinical alternating biplane x-ray imaging system...
June 11, 2018: Medical Physics
Sarah L Krein, Jeanmarie Mayer, Molly Harrod, Lauren E Weston, Lynn Gregory, Laura Petersen, Matthew H Samore, Frank A Drews
Importance: Using personal protective equipment (PPE) and transmission-based precautions are primary strategies for reducing the transmission of infectious agents. Objective: To identify and characterize failures in transmission-based precautions, including PPE use, by health care personnel that could result in self-contamination or transmission during routine, everyday hospital care. Design, Setting, and Participants: This qualitative study involved direct observation inside and outside patient rooms on clinical units from March 1, 2016, to November 30, 2016...
June 11, 2018: JAMA Internal Medicine
Claire L Schwartz, Ashkon Seyed-Safi, Sayeed Haque, Emma P Bray, Shelia Greenfield, F D Richard Hobbs, Paul Little, Jonathan Mant, Bryan Williams, Richard J Mcmanus
OBJECTIVE: Self-management of hypertension can reduce and control blood pressure (BP) compared with clinic monitoring. However, self-management relies on patients following an algorithm, which may be variably adhered to. This study reports fidelity of high-risk patients to the self-management algorithm set by the TASMIN-SR trial. METHODS: Patients with hypertension, above target clinic BP and one or more of stroke, diabetes, coronary heart disease or chronic kidney disease, were invited to self-monitor following an individualized self-titration algorithm...
June 7, 2018: Journal of Hypertension
César Vargas-Blasco, Esperanza L Gómez-Durán, Carles Martin-Fumadó, Josep Arimany-Manso
OBJECTIVES: Data about urology malpractice claims in our environment are scarce and should be considered a potential opportunity to "learn from errors". METHODS: We analyzed every claim for alleged malpractice in Urology managed by the Council of Medical Colleges of Catalonia between 1990 and 2012, and specifically evaluated the clinical and medicolegal features of those cases with medical professional responsibility. RESULTS: We identified 182 cases in 22 years, but only the 25,74%showed professional liability...
June 2018: Archivos Españoles de Urología
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