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Inferior parietal lobule

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https://www.readbyqxmd.com/read/28714728/functional-neural-changes-following-behavioral-therapies-and-disulfiram-for-cocaine-dependence
#1
Elise E DeVito, Guangheng Dong, Hedy Kober, Jiansong Xu, Kathleen M Carroll, Marc N Potenza
A growing literature exists on neural correlates of treatment outcome. However, different types-or components of-treatment have distinct theorized mechanisms of action. And it is not yet known how changes in neural activity across treatment relate to engagement in different treatment components. Participants with cocaine use disorders in a randomized clinical trial received cognitive-behavioral therapy (CBT) plus, in a 2 × 2 design, contingency management (CM) or no CM, and disulfiram or placebo. Participants performed a functional MRI Stroop task, a measure of cognitive control, at the beginning of and after the 12-week treatment...
July 17, 2017: Psychology of Addictive Behaviors: Journal of the Society of Psychologists in Addictive Behaviors
https://www.readbyqxmd.com/read/28707166/altered-dynamic-functional-connectivity-in-the-default-mode-network-in-patients-with-cirrhosis-and-minimal-hepatic-encephalopathy
#2
Hua-Jun Chen, Hai-Long Lin, Qiu-Feng Chen, Peng-Fei Liu
PURPOSE: Abnormal brain intrinsic functional connectivity (FC) has been documented in minimal hepatic encephalopathy (MHE) by static connectivity analysis. However, changes in dynamic FC (dFC) remain unknown. We aimed to identify altered dFC within the default mode network (DMN) associated with MHE. METHODS: Resting-state functional MRI data were acquired from 20 cirrhotic patients with MHE and 24 healthy controls. DMN seed regions were defined using seed-based FC analysis (centered on the posterior cingulate cortex (PCC))...
July 13, 2017: Neuroradiology
https://www.readbyqxmd.com/read/28699075/differential-brain-activations-in-adult-attention-deficit-hyperactivity-disorder-subtypes-a-counting-stroop-functional-mri-study
#3
Chi-Yung Shang, Chia Sheng, Li-Kuang Yang, Tai-Li Chou, Susan Shur-Fen Gau
Although previous functional neuroimaging studies have found abnormal brain activations in individuals with attention deficit hyperactivity disorder (ADHD), little was known about distinct brain dysfunctions across different ADHD subtypes. The objective of the present study was to investigate the abnormal brain activations associated with two ADHD subtypes, predominantly inattentive (ADHD-PI) and combined (ADHD-C) subtypes. Twenty-five adults with ADHD-PI, 25 with ADHD-C, and 30 healthy controls (HC) participated in this study...
July 11, 2017: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/28688854/the-time-course-of-activation-in-the-dorsal-and-ventral-visual-streams-during-landmark-cueing-and-perceptual-discrimination-tasks
#4
Anthony J Lambert, Adrienne Wootton
Different patterns of high density EEG activity were elicited by the same peripheral stimuli, in the context of Landmark Cueing and Perceptual Discrimination tasks. The C1 component of the visual event-related potential (ERP) at parietal - occipital electrode sites was larger in the Landmark Cueing task, and source localisation suggested greater activation in the superior parietal lobule (SPL) in this task, compared to the Perceptual Discrimination task, indicating stronger early recruitment of the dorsal visual stream...
July 5, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28679330/altered-brain-network-centrality-in-patients-with-adult-comitant-exotropia-strabismus-a-resting-state-fmri-study
#5
Gang Tan, Zeng-Renqing Dan, Ying Zhang, Xin Huang, Yu-Lin Zhong, Lin-Hong Ye, Rong Rong, Lei Ye, Qiong Zhou, Yi Shao
Objective To investigate the underlying functional network brain-activity changes in patients with adult comitant exotropia strabismus (CES) and the relationship with clinical features using the voxel-wise degree centrality (DC) method. Methods A total of 30 patients with CES (17 men, 13 women), and 30 healthy controls (HCs; 17 men, 13 women) matched in age, sex, and education level participated in the study. DC was used to evaluate spontaneous brain activity. Receiver operating characteristic (ROC) curve analysis was conducted to distinguish CESs from HCs...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28674492/aberrant-intrinsic-activity-and-connectivity-in-cognitively-normal-parkinson-s-disease
#6
Deborah L Harrington, Qian Shen, Gabriel N Castillo, J Vincent Filoteo, Irene Litvan, Colleen Takahashi, Chelsea French
Disturbances in intrinsic activity during resting-state functional MRI (rsfMRI) are common in Parkinson's disease (PD), but have largely been studied in a priori defined subnetworks. The cognitive significance of abnormal intrinsic activity is also poorly understood, as are abnormalities that precede the onset of mild cognitive impairment. To address these limitations, we leveraged three different analytic approaches to identify disturbances in rsfMRI metrics in 31 cognitively normal PD patients (PD-CN) and 30 healthy adults...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28672395/association-between-motor-symptoms-and-brain-metabolism-in-early-huntington-disease
#7
Véronique Gaura, Sonia Lavisse, Pierre Payoux, Serge Goldman, Christophe Verny, Pierre Krystkowiak, Philippe Damier, Frédéric Supiot, Anne-Catherine Bachoud-Levi, Philippe Remy
Importance: Brain hypometabolism is associated with the clinical consequences of the degenerative process, but little is known about regional hypermetabolism, sometimes observed in the brain of patients with clinically manifest Huntington disease (HD). Studying the role of regional hypermetabolism is needed to better understand its interaction with the motor symptoms of the disease. Objective: To investigate the association between brain hypometabolism and hypermetabolism with motor scores of patients with early HD...
July 3, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/28649941/treatment-effects-of-olanzapine-on-homotopic-connectivity-in-drug-free-schizophrenia-at-rest
#8
Wenbin Guo, Feng Liu, Jindong Chen, Renrong Wu, Lehua Li, Zhikun Zhang, Huafu Chen, Jingping Zhao
OBJECTIVES: Deficits in homotopic connectivity have been implicated in schizophrenia. However, alterations in homotopic connectivity associated with antipsychotic treatments in schizophrenia remain unclear due to lack of longitudinal studies. METHODS: Seventeen drug-free patients with recurrent schizophrenia and twenty-four healthy controls underwent resting-state functional magnetic resonance imaging scans. The patients were scanned at three time points (baseline, 6 weeks of treatment, and 6 months of treatment)...
June 26, 2017: World Journal of Biological Psychiatry
https://www.readbyqxmd.com/read/28649490/frequency-dependent-changes-in-local-intrinsic-oscillations-in-chronic-primary-insomnia-a-study-of-the-amplitude-of-low-frequency-fluctuations-in-the-resting-state
#9
Fuqing Zhou, Suhua Huang, Ying Zhuang, Lei Gao, Honghan Gong
New neuroimaging techniques have led to significant advancements in our understanding of cerebral mechanisms of primary insomnia. However, the neuronal low-frequency oscillation remains largely uncharacterized in chronic primary insomnia (CPI). In this study, the amplitude of low-frequency fluctuation (ALFF), a data-driven method based on resting-state functional MRI, was used to examine local intrinsic activity in 27 patients with CPI and 27 age-, sex-, and education-matched healthy controls. We examined neural activity in two frequency bands, slow-4 (between 0...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28627941/detecting-social-cognitive-deficits-after-traumatic-brain-injury-an-ale-meta-analysis-of-fmri-studies
#10
Hui Xiao, Andre Jacobsen, Ziqian Chen, Yang Wang
PURPOSE: Traumatic brain injury (TBI) can result in significant social dysfunction, which is represented by impairment to social-cognitive abilities (i.e. social cognition, social attention/executive function and communication). This study is aimed to explore brain networks mediating the social dysfunction after TBI and its underlying mechanisms. METHODS: We performed a quantitative meta-analysis using the activation likelihood estimation (ALE) approach on functional magnetic resonance imaging (fMRI) studies of social-cognitive abilities following TBI...
June 19, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28624581/polygenic-risk-for-depression-and-the-neural-correlates-of-working-memory-in-healthy-subjects
#11
Dilara Yüksel, Bruno Dietsche, Andreas J Forstner, Stephanie H Witt, Robert Maier, Marcella Rietschel, Carsten Konrad, Markus M Nöthen, Udo Dannlowski, Bernhard T Baune, Tilo Kircher, Axel Krug
INTRODUCTION: Major depressive disorder (MDD) patients show impairments of cognitive functioning such as working memory (WM), and furthermore alterations during WM-fMRI tasks especially in frontal and parietal brain regions. The calculation of a polygenic risk score (PRS) can be used to describe the genetic influence on MDD, hence imaging genetic studies aspire to combine both genetics and neuroimaging data to identify the influence of genetic factors on brain functioning. We aimed to detect the effect of MDD-PRS on brain activation during a WM task measured with fMRI and expect healthy individuals with a higher PRS to be more resembling to MDD patients...
June 15, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28619530/neural-networks-underlying-language-and-social-cognition-during-self-other-processing-in-autism-spectrum-disorders
#12
Rajesh K Kana, Emma B Sartin, Carl Stevens, Hrishikesh D Deshpande, Christopher Klein, Mark R Klinger, Laura Grofer Klinger
The social communication impairments defining autism spectrum disorders (ASD) may be built upon core deficits in perspective-taking, language processing, and self-other representation. Self-referential processing entails the ability to incorporate self-awareness, self-judgment, and self-memory in information processing. Very few studies have examined the neural bases of integrating self-other representation and semantic processing in individuals with ASD. The main objective of this functional MRI study is to examine the role of language and social brain networks in self-other processing in young adults with ASD...
June 12, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28605972/resting-state-connectivity-between-default-mode-network-and-insula-encodes-acute-migraine-headache
#13
Gianluca Coppola, Antonio Di Renzo, Emanuele Tinelli, Cherubino Di Lorenzo, Marco Scapeccia, Vincenzo Parisi, Mariano Serrao, Maurizio Evangelista, Anna Ambrosini, Claudio Colonnese, Jean Schoenen, Francesco Pierelli
Background Previous functional MRI studies have revealed that ongoing clinical pain in different chronic pain syndromes is directly correlated to the connectivity strength of the resting default mode network (DMN) with the insula. Here, we investigated seed-based resting state DMN-insula connectivity during acute migraine headaches. Methods Thirteen migraine without aura patients (MI) underwent 3 T MRI scans during the initial six hours of a spontaneous migraine attack, and were compared to a group of 19 healthy volunteers (HV)...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28605410/abstract-representations-of-object-directed-action-in-the-left-inferior-parietal-lobule
#14
Quanjing Chen, Frank E Garcea, Robert A Jacobs, Bradford Z Mahon
Prior neuroimaging and neuropsychological research indicates that the left inferior parietal lobule in the human brain is a critical substrate for representing object manipulation knowledge. In the present functional MRI study we used multivoxel pattern analyses to test whether action similarity among objects can be decoded in the inferior parietal lobule independent of the task applied to objects (identification or pantomime) and stimulus format in which stimuli are presented (pictures or printed words). Participants pantomimed the use of objects, cued by printed words, or identified pictures of objects...
June 9, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28598839/functional-disintegration-of-the-default-mode-network-in-prodromal-alzheimer-s-disease
#15
Kim N H Dillen, Heidi I L Jacobs, Juraj Kukolja, Nils Richter, Boris von Reutern, Özgür A Onur, Karl-Josef Langen, Gereon R Fink
Neurodegenerative brain changes can affect the functional connectivity strength between nodes of the default-mode network (DMN), which may underlie changes in cognitive performance. It remains unclear how the functional connectivity strength of DMN nodes differs from healthy to pathological aging and whether these changes are cognitively relevant. We used resting-state functional magnetic resonance imaging to investigate the functional connectivity strength across five DMN nodes in 25 healthy controls (HC), 28 subjective cognitive decline (SCD) participants, and 25 prodromal Alzheimer's disease (AD) patients...
2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28587813/abnormal-regional-homogeneity-as-a-potential-imaging-biomarker-for-adolescent-onset-schizophrenia-a-resting-state-fmri-study-and-support-vector-machine-analysis
#16
Shuai Wang, Yan Zhang, Luxian Lv, Renrong Wu, Xiaoduo Fan, Jingping Zhao, Wenbin Guo
OBJECTIVE: Structural and functional abnormalities have been reported in the brain of patients with adolescent-onset schizophrenia (AOS). The brain regional functional synchronization in patients with AOS remains unclear. METHODS: We analyzed resting-state functional magnetic resonance scans in 48 drug-naive patients with AOS and 31 healthy controls by using regional homogeneity (ReHo), a measurement that reflects brain local functional connectivity or synchronization and indicates regional integration of information processing...
June 3, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28579400/emotion-regulation-in-mood-and-anxiety-disorders-a-meta-analysis-of-fmri-cognitive-reappraisal-studies
#17
REVIEW
Maria Picó-Pérez, Joaquim Radua, Trevor Steward, José M Menchón, Carles Soriano-Mas
Emotion regulation by means of cognitive reappraisal has been widely studied with functional magnetic resonance imaging (fMRI). To date, several meta-analyses of studies using cognitive reappraisal tasks in healthy volunteers have been carried out, but no meta-analyses have yet been performed on the fMRI data of clinical populations with identified alterations in emotion regulation capacity. We provide a comprehensive meta-analysis of cognitive reappraisal fMRI studies in populations of patients with mood or anxiety disorders, yielding a pooled sample of 247 patients and 262 controls from thirteen independent studies...
June 1, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28578155/prefrontal-parietal-effective-connectivity-during-working-memory-in-older-adults
#18
Stephan Heinzel, Robert C Lorenz, Quynh-Lam Duong, Michael A Rapp, Lorenz Deserno
Theoretical models and preceding studies have described age-related alterations in neuronal activation of frontoparietal regions in a working memory (WM) load-dependent manner. However, to date, underlying neuronal mechanisms of these WM load-dependent activation changes in aging remain poorly understood. The aim of this study was to investigate these mechanisms in terms of effective connectivity by application of dynamic causal modeling with Bayesian Model Selection. Eighteen healthy younger (age: 20-32 years) and 32 older (60-75 years) participants performed an n-back task with 3 WM load levels during functional magnetic resonance imaging (fMRI)...
May 10, 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/28572034/decreased-middle-temporal-gyrus-connectivity-in-the-language-network-in-schizophrenia-patients-with-auditory-verbal-hallucinations
#19
Linchuan Zhang, Baojuan Li, Huaning Wang, Liang Li, Qimei Liao, Yang Liu, Xianghong Bao, Wenlei Liu, Hong Yin, Hongbing Lu, Qingrong Tan
As the most common symptoms of schizophrenia, the long-term persistence of obstinate auditory verbal hallucinations (AVHs) brings about great mental pain to patients. Neuroimaging studies of schizophrenia have indicated that AVHs were associated with altered functional and structural connectivity within the language network. However, effective connectivity that could reflect directed information flow within this network and is of great importance to understand the neural mechanisms of the disorder remains largely unknown...
July 13, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28560154/children-with-cerebral-palsy-have-altered-oscillatory-activity-in-the-motor-and-visual-cortices-during-a-knee-motor-task
#20
Max J Kurz, Amy L Proskovec, James E Gehringer, Elizabeth Heinrichs-Graham, Tony W Wilson
The neuroimaging literature on cerebral palsy (CP) has predominantly focused on identifying structural aberrations within the white matter (e.g., fiber track integrity), with very few studies examining neural activity within the key networks that serve the production of motor actions. The current investigation used high-density magnetoencephalography to begin to fill this knowledge gap by quantifying the temporal dynamics of the alpha and beta cortical oscillations in children with CP (age = 15.5 ± 3 years; GMFCS levels II-III) and typically developing (TD) children (age = 14...
2017: NeuroImage: Clinical
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