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Inferior parietal lobule

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https://www.readbyqxmd.com/read/28106554/recovery-from-proactive-semantic-interference-in-mild-cognitive-impairment-and-normal-aging-relationship-to-atrophy-in-brain-regions-vulnerable-to-alzheimer-s-disease
#1
David A Loewenstein, Rosie E Curiel, Clinton Wright, Xiaoyan Sun, Noam Alperin, Elzabeth Crocco, Sara J Czaja, Arlene Raffo, Ailyn Penate, Jose Melo, Kimberly Capp, Monica Gamez, Ranjan Duara
BACKGROUND: There is growing evidence that proactive semantic interference (PSI) and failure to recover from PSI may represent early features of Alzheimer's disease (AD). OBJECTIVE: This study investigated the association between PSI, recovery from PSI, and reduced MRI volumes in AD signature regions among cognitively impaired and unimpaired older adults. METHODS: Performance on the LASSI-L (a novel test of PSI and recovery from PSI) and regional brain volumetric measures were compared between 38 cognitively normal (CN) elders and 29 older participants with amnestic mild cognitive impairment (MCI)...
January 18, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28104637/cortical-thickness-of-native-tibetans-in-the-qinghai-tibetan-plateau
#2
W Wei, X Wang, Q Gong, M Fan, J Zhang
BACKGROUND AND PURPOSE: High-altitude environmental factors and genetic variants together could have exerted their effects on the human brain. The present study was designed to investigate the cerebral morphology in high-altitude native Tibetans. MATERIALS AND METHODS: T1-weighted brain images were obtained from 77 Tibetan adolescents on the Qinghai-Tibetan Plateau (altitude, 2300-5300 m) and 80 matched Han controls living at sea level. Cortical thickness, curvature, and sulcus were analyzed by using FreeSurfer...
January 19, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28094811/brain-connectivity-changes-occurring-following-cognitive-behavioural-therapy-for-psychosis-predict-long-term-recovery
#3
L Mason, E Peters, S C Williams, V Kumari
Little is known about the psychobiological mechanisms of cognitive behavioural therapy for psychosis (CBTp) and which specific processes are key in predicting favourable long-term outcomes. Following theoretical models of psychosis, this proof-of-concept study investigated whether the long-term recovery path of CBTp completers can be predicted by the neural changes in threat-based social affective processing that occur during CBTp. We followed up 22 participants who had undergone a social affective processing task during functional magnetic resonance imaging along with self-report and clinician-administered symptom measures, before and after receiving CBTp...
January 17, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28079163/steady-state-and-dynamic-network-modes-for-perceptual-expectation
#4
Uk-Su Choi, Yul-Wan Sung, Seiji Ogawa
Perceptual expectation can attenuate repetition suppression, the stimulus-induced neuronal response generated by repeated stimulation, suggesting that repetition suppression is a top-down modulatory phenomenon. However, it is still unclear which high-level brain areas are involved and how they interact with low-level brain areas. Further, the temporal range over which perceptual expectation can effectively attenuate repetition suppression effects remains unclear. To elucidate the details of this top-down modulatory process, we used two short and long inter-stimulus intervals for a perceptual expectation paradigm of paired stimulation...
January 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28060546/gray-matter-hypertrophy-and-thickening-with-obstructive-sleep-apnea-in-middle-aged-and-older-adults
#5
Andrée-Ann Baril, Katia Gagnon, Pauline Brayet, Jacques Montplaisir, Louis De Beaumont, Julie Carrier, Chantal Lafond, Francis L'Heureux, Jean-François Gagnon, Nadia Gosselin
RATIONALE: Obstructive sleep apnea causes intermittent hypoxemia, hemodynamic fluctuations, and sleep fragmentation, all of which could damage cerebral gray matter that can be indirectly assessed with neuroimaging. OBJECTIVES: To investigate whether markers of obstructive sleep apnea severity are associated with gray matter changes among middle-aged and older individuals. METHODS: Seventy-one subjects (ages: 55 to 76; apnea-hypopnea index: 0...
January 6, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28059657/language-outcomes-after-resection-of-dominant-inferior-parietal-lobule-gliomas
#6
Derek G Southwell, Marco Riva, Kesshi Jordan, Eduardo Caverzasi, Jing Li, David W Perry, Roland G Henry, Mitchel S Berger
OBJECTIVE The dominant inferior parietal lobule (IPL) contains cortical and subcortical regions essential for language. Although resection of IPL tumors could result in language deficits, little is known about the likelihood of postoperative language morbidity or the risk factors predisposing to this outcome. METHODS The authors retrospectively examined a series of patients who underwent resections of gliomas from the dominant IPL. Postoperative language outcomes were characterized across the patient population...
January 6, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28057458/the-inferior-parietal-lobule-and-temporoparietal-junction-a-network-perspective
#7
Kajsa M Igelström, Michael S A Graziano
Information processing in specialized, spatially distributed brain networks underlies the diversity and complexity of our cognitive and behavioral repertoire. Networks converge at a small number of hubs - highly connected regions that are central for multimodal integration and higher-order cognition. We review one major network hub of the human brain: the inferior parietal lobule and the overlapping temporoparietal junction (IPL/TPJ). The IPL is greatly expanded in humans compared to other primates and matures late in human development, consistent with its importance in higher-order functions...
January 2, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28048305/su-f-j-139-amplitude-of-low-frequency-fluctuation-alff-and-regional-homogeneity-reho-study-of-the-respiration-motion-control-byhypnosis
#8
Y Liu, R Li, Y Xie
PURPOSE: Respiration control by hypnosis is a method in reducing the detriment to the healthy organs or organizations for patients during radiotherapy, especially for lung and abdomen cancer (Fig.1). It's hypothesized that there exists alterations neurological brain activity during the hypnosis state of respiratory motion control in comparison with resting state. METHODS: Thirteen healthy volunteers were organized to participate in a hypnosis experiment that consisted of two sectional scans of functional magnetic resonance imaging (fMRI), rest state condition (RSC) scanning and hypnosis state condition (HSC) scanning...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28045222/correspondent-functional-topography-of-the-human-left-inferior-parietal-lobule-at-rest-and-under-task-revealed-using-resting-state-fmri-and-coactivation-based-parcellation
#9
Jiaojian Wang, Sangma Xie, Xin Guo, Benjamin Becker, Peter T Fox, Simon B Eickhoff, Tianzi Jiang
The human left inferior parietal lobule (LIPL) plays a pivotal role in many cognitive functions and is an important node in the default mode network (DMN). Although many previous studies have proposed different parcellation schemes for the LIPL, the detailed functional organization of the LIPL and the exact correspondence between the DMN and LIPL subregions remain unclear. Mounting evidence indicates that spontaneous fluctuations in the brain are strongly associated with cognitive performance at the behavioral level...
January 3, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28041615/functional-anatomy-of-the-macaque-temporo-parieto-frontal-connectivity
#10
REVIEW
Elena Borra, Giuseppe Luppino
The primate parietal lobe is primarily dedicated to the processing of sensory information for the guidance of motor behavior, based on the integration of sensory with motor signals (sensorimotor transformations), mediated by specific, strong, and reciprocal connections with the motor cortex. Sensorimotor transformations have been regarded as an automatic process carried out independently from the temporal cortex, which is considered the location where sensory information is used for perceptual processes. However, both human and non-human primate studies have shown interactions between these two regions in different aspects of sensorimotor and cognitive processes...
December 18, 2016: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28006783/altered-long-and-short-range-functional-connectivity-in-patients-with-betel-quid-dependence-a-resting-state-functional-mri-study
#11
Tao Liu, Jianjun Li, Zhiqiang Zhang, Qiang Xu, Guangming Lu, Shixiong Huang, Mengjie Pan, Feng Chen
OBJECTIVE: Addiction is a chronic relapsing brain disease. Brain structural abnormalities may constitute an abnormal neural network that underlies the risk of drug dependence. We hypothesized that individuals with Betel Quid Dependence (BQD) have functional connectivity alterations that can be described by long- and short-range functional connectivity density(FCD) maps. METHODS: We tested this hypothesis using functional magnetic resonance imaging (fMRI) data from subjects of the Han ethnic group in Hainan, China...
2016: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/28005183/altered-gray-matter-volume-in-stable-chronic-obstructive-pulmonary-disease-with-subclinical-cognitive-impairment-an-exploratory-study
#12
Chunrong Wang, Yanhui Ding, Bixian Shen, Dehong Gao, Jie An, Kewen Peng, Gangqiang Hou, Liqiu Zou, Mei Jiang, Shijun Qiu
Gray matter volume deficits have been identified in cognitively impaired patients with chronic obstructive pulmonary disease (COPD). However, it remains unknown whether the gray matter volume is altered in COPD patients with subclinical cognitive impairment. To determine whether any gray matter abnormalities are present in these patients, neuropsychological tests and structural MRI data were analyzed from 60 patients with COPD and 60 age-, gender-, education-, and handedness-matched normal controls (NCs). The COPD patients had similar Mini-Mental State Examination (MMSE) scores compared with the NCs...
December 22, 2016: Neurotoxicity Research
https://www.readbyqxmd.com/read/28000557/the-resting-state-functional-connectivity-of-the-default-mode-networks-in-patients-with-obstructive-sleep-apnea-hypopnea-syndrome
#13
Ting Chen, Ming Yang, Bin Liu, Yu-Ting Liu, Hui-Xin Zhang, Chuan-Chuan Liu, Yue Zhu, Zhi-Chun Huang, Ti-Fei Yuan
Obstructive sleep apnea-hypopnea syndrome (OSAHS) is normally linked to cognitive and functional dysfunctions. In this study, we explored the resting-state functional connectivity (rsFC) in the default mode network (DMN) to show the mechanism of neurophysiology in patients with OSAHS. Resting-state structural and functional Magnetic Resonance Imaging data were obtained from sixteen male moderate-to- severe patients with untreated OSAHS and 15 male matched healthy control subjects. The rsFC in the DMN was analyzed between OSAHS and healthy controls by the CONN software...
December 19, 2016: CNS & Neurological Disorders Drug Targets
https://www.readbyqxmd.com/read/27999530/disturbed-interhemispheric-functional-connectivity-rather-than-structural-connectivity-in-irritable-bowel-syndrome
#14
Rongfeng Qi, Chang Liu, Yifei Weng, Qiang Xu, Liya Chen, Fangyu Wang, Long J Zhang, Guang M Lu
Neuroimaging studies have demonstrated that irritable bowel syndrome (IBS)-a relapsing functional bowel disorder-presents with disrupted brain connections. However, little is known about the alterations of interhemispheric functional connectivity and underlying structural connectivity in IBS. This study combined resting-state functional magnetic resonance imaging (rs-fMRI) and diffusion tensor imaging (DTI) to investigate changes in interhemispheric coordination in IBS patients. Resting-state functional and structural magnetic resonance images were acquired from 65 IBS patients and 67 healthy controls (HCs; matched for age, sex and educational level)...
2016: Frontiers in Molecular Neuroscience
https://www.readbyqxmd.com/read/27994546/decreased-subcortical-and-increased-cortical-degree-centrality-in-a-nonclinical-college-student-sample-with-subclinical-depressive-symptoms-a-resting-state-fmri-study
#15
Cuihua Gao, Liu Wenhua, Yanli Liu, Xiuhang Ruan, Xin Chen, Lingling Liu, Shaode Yu, Raymond C K Chan, Xinhua Wei, Xinqing Jiang
Abnormal functional connectivity (FC) at rest has been identified in clinical depressive disorder. However, very few studies have been conducted to understand the underlying neural substrates of subclinical depression. The newly proposed centrality analysis approach has been increasingly used to explore the large-scale brain network of mental diseases. This study aimed to identify the degree centrality (DC) alteration of the brain network in subclinical depressive subjects. Thirty-seven candidates with subclinical depression and 34 well-matched healthy controls (HCs) were recruited from the same sample of college students...
2016: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/27986609/the-neural-circuits-for-arithmetic-principles
#16
Jie Liu, Han Zhang, Chuansheng Chen, Hui Chen, Jiaxin Cui, Xinlin Zhou
Arithmetic principles are the regularities underlying arithmetic computation. Little is known about how the brain supports the processing of arithmetic principles. The current fMRI study examined neural activation and functional connectivity during the processing of verbalized arithmetic principles, as compared to numerical computation and general language processing. As expected, arithmetic principles elicited stronger activation in bilateral horizontal intraparietal sulcus and right supramarginal gyrus than did language processing, and stronger activation in left middle temporal lobe and left orbital part of inferior frontal gyrus than did computation...
December 14, 2016: NeuroImage
https://www.readbyqxmd.com/read/27935359/microsurgical-and-endoscopic-approaches-to-the-pulvinar
#17
Osamu Akiyama, Ken Matsushima, Abuzer Gungor, Satoshi Matsuo, Dylan J Goodrich, R Shane Tubbs, Paul Klimo, Aaron A Cohen-Gadol, Hajime Arai, Albert L Rhoton
OBJECTIVE Approaches to the pulvinar remain challenging because of the depth of the target, surrounding critical neural structures, and complicated arterial and venous relationships. The purpose of this study was to compare the surgical approaches to different parts of the pulvinar and to examine the efficacy of the endoscope as an adjunct to the operating microscope in this area. METHODS The pulvinar was examined in 6 formalin-fixed human cadaveric heads through 5 approaches: 4 above and 1 below the tentorium...
December 9, 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27916710/aberrant-regional-homogeneity-in-parkinson-s-disease-a-voxel-wise-meta-analysis-of-resting-state-functional-magnetic-resonance-imaging-studies
#18
REVIEW
PingLei Pan, Hui Zhan, MingXu Xia, Yang Zhang, DeNing Guan, Yun Xu
Studies of abnormal regional homogeneity (ReHo) in Parkinson's disease (PD) have reported inconsistent results. Therefore, we conducted a meta-analysis using the Seed-based d Mapping software package to identify the most consistent and replicable findings. A systematic literature search was performed to identify eligible whole-brain resting-state functional magnetic resonance imaging studies that had measured differences in ReHo between patients with PD and healthy controls between January 2000 and June 4, 2016...
January 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/27911308/the-effects-of-gene-mutations-on%C3%A2-default%C3%A2-mode-network-in%C3%A2-familial%C3%A2-alzheimer-s-disease
#19
Xiaozhen Li, Eric Westman, Steinunn Thordardottir, Anne Kinhult Ståhlbom, Ove Almkvist, Kaj Blennow, Lars-Olof Wahlund, Caroline Graff
Familial Alzheimer's disease (FAD) mutations have very high penetrance but age at onset and rate of disease progression differ. Neuroimaging and cerebrospinal fluid (CSF) examinations in mutation carriers (MCs) may provide an opportunity to identify early biomarkers that can be used to track disease progression from presymptomatic to the dementia stages of disease. The default mode network (DMN) is a resting state neuronal network composed of regions known to associate with amyloid deposition in AD. We hypothesized that functional connectivity in the DMN might change at pre-clinical stages in FAD MCs and correlate with changes in CSF biomarkers as a consequence of AD brain pathology...
November 29, 2016: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/27909422/the-role-of-medial-frontal-cortex-in-action-anticipation-in-professional-badminton-players
#20
Huan Xu, Pin Wang, Zhuo'er Ye, Xin Di, Guiping Xu, Lei Mo, Huiyan Lin, Hengyi Rao, Hua Jin
Some studies show that the medial frontal cortex is associated with more skilled action anticipation, while similar findings are not observed in some other studies, possibly due to the stimuli employed and the participants used as the control group. In addition, no studies have investigated whether there is any functional connectivity between the medial frontal cortex and other brain regions in more skilled action anticipation. Therefore, the present study aimed to re-investigate how the medial frontal cortex is involved in more skilled action anticipation by circumventing the limitations of previous research and to investigate that the medial frontal cortex functionally connected with other brain regions involved in action processing in more skilled action anticipation...
2016: Frontiers in Psychology
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