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Climatic and coronary arterial disease

Ahmadreza Argha, Andrey Savkin, Siaw-Teng Liaw, Branko George Celler
BACKGROUND: Seasonal variation has an impact on the hospitalization rate of patients with a range of cardiovascular diseases, including myocardial infarction and angina. This paper presents findings on the influence of seasonal variation on the results of a recently completed national trial of home telemonitoring of patients with chronic conditions, carried out at five locations along the east coast of Australia. OBJECTIVE: The aim is to evaluate the effect of the seasonal timing of hospital admission and length of stay on clinical outcome of a home telemonitoring trial involving patients (age: mean 72...
March 16, 2018: JMIR Medical Informatics
Mario Hensel, Markus Stuhr, Daniel Geppert, Jan F Kersten, Jürgen Lorenz, Thoralf Kerner
OBJECTIVE: To test the hypothesis that more cardiovascular emergencies occur at low rather than at high temperatures under moderate climatic conditions. METHODS: This was a prospective observational study performed in a prehospital setting. Data from the Emergency Medical Service in Hamburg (Germany) and from the local weather station were evaluated over a 5-year period. Temperature data were matched with the associated rescue mission data. Lowess-Regression analysis was performed to assess the relationship between the temperature and the frequency of individual cardiovascular emergencies...
February 1, 2017: International Journal of Cardiology
J Nadel, C J Holloway
HIV infection is now considered a chronic, treatable disease, although treatment is associated with increased rates of coronary artery disease (CAD). Increased risk of CAD in HIV-infected patients has been associated with the inflammatory sequelae of the infection as well as the greater prevalence of cardiac risk factors in HIV-positive populations and the side effects of life-prolonging antiretroviral therapies. Patients with HIV infection now have a 1.5 to 2-fold greater risk of developing CAD compared with noninfected individuals, raising the independent risk of CAD in HIV infection to levels similar to those in diabetes...
April 2017: HIV Medicine
Wen-fang Xia, Qi-zhu Tang, Sheng-bo Yu, Hong-ying Cui, Mu Qin, Tao Liu, Bin Kong, Qing-yan Zhao, He Huang, Cong-xin Huang
OBJECTIVE: To investigate the effect of temperature on hospital admission among patients with chronic systolic heart failure (CSHF). METHODS: Data regarding in-hospital patients with CSHF were gathered from 12 hospitals in Hubei province, between 2000 and 2010. Patients with a history of congenital heart disease and the history of cancer from this series, were excluded. Chi-square (χ(2)) tests and t tests were used for descriptive analysis. Univariate and multivariate logistic regression methods were performed to determinate the risk of hospital admission of every month to compare with the previous one...
January 2013: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
M Wanitschek, H Ulmer, A Süssenbacher, J Dörler, O Pachinger, H F Alber
BACKGROUND: Weather conditions influence symptoms in chronic stable coronary artery disease (CAD). Whether the ongoing climate change, with continuous and rapid temperature increases, also has an impact on the incidence and outcome of non-ST elevation (NSTEMI) and ST elevation (STEMI) myocardial infarctions referred for acute coronary angiography (CA) is less clear. METHODS: According to weather data from the Institute of Meteorology and Geophysics, Innsbruck University, the 2005/2006 winter was very cold (CW) and the 2006/2007 winter extraordinarily warm (WW)...
March 2013: Herz
Robert B Nichols, William F McIntyre, Salina Chan, David Scogstad-Stubbs, Wilma M Hopman, Adrian Baranchuk
BACKGROUND: Snow-shoveling is a necessary activity for those living in temperate climates, but there are no large studies identifying a connection between this activity and the development of acute coronary syndromes (ACS). OBJECTIVES: The aim of this study was to identify potential factors that place individuals at higher risk for developing a snow-shoveling-related ACS. METHODS: We performed a chart review over two consecutive winter seasons to identify a sample of ACS events associated with shoveling snow...
January 2012: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
Neal B Patel, Gary J Balady
Coronary artery disease (CAD) continues to be the most common cause of morbidity and mortality in patients with diabetes mellitus (DM). In recent years, the strategies for treatment of CAD in DM have undergone much evolution. Currently, all patients with DM, regardless of symptoms or diagnosed CAD, are treated aggressively for CAD risk factor reduction. In this clinical climate, the ability to specifically identify patients with disease that will benefit from more aggressive and invasive therapies remains a challenge...
March 2010: Reviews in Endocrine & Metabolic Disorders
Andrew Cassar, David R Holmes, Charanjit S Rihal, Bernard J Gersh
Coronary artery disease (CAD) is the single most common cause of death in the developed world, responsible for about 1 in every 5 deaths. The morbidity, mortality, and socioeconomic importance of this disease make timely accurate diagnosis and cost-effective management of CAD of the utmost importance. This comprehensive review of the literature highlights key elements in the diagnosis, risk stratification, and management strategies of patients with chronic CAD. Relevant articles were identified by searching the PubMed database for the following terms: chronic coronary artery disease or stable angina...
December 2009: Mayo Clinic Proceedings
Ole Faergeman
Infectious diseases, malnutrition, et cetera will all become more common as the earth gets warmer and the climate becomes more unstable. Even though obesity, type II diabetes and coronary artery disease do not result from climate change, they do share causes with climate change. The production of livestock in agriculture, for example, is an important source of greenhouse gas emissions as well as a source of many of our most energy-rich foods. Physicians and medical societies should therefore contribute to the public debate about climate change and what to do about it...
August 25, 2008: Ugeskrift for Laeger
Edmund R Becker, Douglas W Roblin
BACKGROUND: Little is known about processes by which proactive primary care teams might activate their patients. We examine the role of trust in patient-physician relationships for translating practice teamwork into patient activation. METHODS: Data were collected by surveys of adult enrollees and primary care teams of a group-model managed care organization in metropolitan Atlanta. Enrollees who were 25-59 years of age were randomly sampled from 3 condition cohorts (diabetes, elevated lipids but no coronary artery disease history, and low risk)...
August 2008: Medical Care
Ole Faergeman
Thermal stress, food poisoning, infectious diseases, malnutrition, psychiatric illness as well as injury and death from floods, storms and fire are all likely to become more common as the earth warms and the climate becomes more variable. In contrast, obesity, type II diabetes and coronary artery disease do not result from climate change, but they do share causes with climate change. Burning fossil fuels, for example, is the major source of greenhouse gases, but it also makes pervasive physical inactivity possible...
December 2007: European Journal of Cardiovascular Prevention and Rehabilitation
Elwira Telejko
BACKGROUND: The efficacy of the angiotensin-converting enzyme (ACE) inhibitor perindopril in the treatment of hypertension, stable coronary artery disease, and heart failure is well established. The reduced stability of the current salt, perindopril-tert-butylamine, in extreme climatic conditions has prompted research into more stable compounds. This article presents stability and bioequivalence results for a new L-arginine salt of perindopril. METHODS: Drug stability studies were performed on nonsalified perindopril, perindopril-tert-butylamine, and perindopril arginine in closed and open containers...
May 2007: Current Medical Research and Opinion
Ambika Gopalakrishnan Unnikrishnan, Palaniswamy Gowri, Kannan Arun, Ajit Kumar Varma, Harish Kumar
CONTEXT: It is well-known that subjects with diabetes resulting from tropical chronic pancreatitis are prone to diabetic microvascular complications (neuropathy, nephropathy and retinopathy). However, macrovascular complications (coronary artery disease, stroke and peripheral vessel disease) are rare, as these subjects are younger, leaner and have lower cholesterol levels. CASE REPORT: We report the case of a 51-year-old male who had tropical chronic pancreatitis, diabetes and severe peripheral vessel disease with gangrene...
March 10, 2007: JOP: Journal of the Pancreas
Gautam Nayak, Daniel Seidensticker, Daniel Shmorhun
As Operation Iraqi Freedom enters its third year, the multinational military force remains engaged in a complex mission based on the military and political climate in the Middle East. As US Navy cardiologists deployed to Kuwait, our experiences proved diverse as we learned to practice in an austere environment. From the evaluation of chest pain to the treatment of coronary artery disease and arrhythmia, patient care was tempered by our ability to use our clinical acumen, physical exam and basic objective data to establish definitive dispositions...
2007: Cardiology
Ram B Singh, Daniel Pella, Nirankar S Neki, J P Chandel, Saurabh Rastogi, Heideki Mori, Kuniaki Otsuka, Pankaj Gupta
Acute myocardial infarction (AMI) is a highly dynamic event, which is associated with marked neuroendocrinological dysfunction in addition to cardiac damage. The immediate trigger for AMI is not precisely known. Studies conducted by Lown, Braunwald, Halberg, Otsuka and our group have demonstrated a marked increase in sympathetic activity, oxidative stress, and magnesium and potassium deficiency during AMI. Clinical studies have reported an increased incidence of AMI, sudden death and ischemia during first quarter of the day when there is a rapid withdrawal of vagal activity and increase in sympathetic tone...
October 2004: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
H Walthall, S Ray, D Robson
Coronary heart disease and its management continue to be at the centre of Government health policy. The present political climate demands clinical effectiveness and best practice should be established, while maintaining the philosophy of cost-effectiveness and resource management. These directives have led practitioners to question the care of patients following coronary artery bypass surgery, in particular the role of mechanical ventilation and the subsequent act of extubation. A retrospective study of 89 patients who had coronary artery bypass grafts (emergency and elective) was undertaken, to establish if extubation had a significant effect on the haemodynamic status of patients with variable degrees of left ventricular function (19% with poor left ventricular function)...
October 2001: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
Jennifer Walsh, Ross Prpic, Carmel Goodman, Brian Dawson, Joseph Hung
PURPOSE: The purpose of this study was to determine and compare the thermoregulatory and hemodynamic responses to moderate intensity exercise (60% of peak oxygen consumption [.VO(2peak)]) in warm (35 degrees C, 45% relative humidity) and cool (18 degrees C, 65% relative humidity) environments in men who had previously undergone coronary artery bypass graft (CABG) surgery and healthy control subjects, matched for age and body composition. METHODS: Fourteen post-CABG men and 16 healthy control subjects were recruited and walked 40 minutes at a moderate intensity, in randomized order, in warm and cool environments (on separate days)...
January 2002: Journal of Cardiopulmonary Rehabilitation
T A Jacobson
Since the publication of the second set of guidelines by the National Cholesterol Education Program, a solid body of data from landmark clinical studies has demonstrated that reduction in low-density lipoprotein (LDL) cholesterol with 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor ("statin") therapy sharply diminishes the risk for coronary artery disease. These trials include the Scandinavian Simvastatin Survival Study, the West of Scotland Coronary Prevention Study, the Air Force/Texas Coronary Atherosclerosis Prevention Study, the Cholesterol and Recurrent Events investigation, and the Long-Term Intervention with Pravastatin in Ischaemic Disease trial...
October 3, 2000: Annals of Internal Medicine
L J Shaw, D D Miller, D S Berman, R Hachamovitch
The future of nuclear medicine procedures, as understood within our current economic climate, depends upon its ability to provide relevant clinical information at similar or lower comparative costs. With an ever-increasing emphasis on cost containment, outcome assessment forms the basis of preserving the quality of patient care. Today, outcomes assessment encompasses a wide array of subjects including clinical, economic, and humanistic (i.e., quality of life) outcomes. For nuclear cardiology, evidence-based medicine would require a threshold level of evidence in order to justify the added cost of any test in a patient's work-up...
June 2000: Quarterly Journal of Nuclear Medicine
R A Kloner, W K Poole, R L Perritt
BACKGROUND: Previous studies have suggested that there is an increase in cardiac events in the morning. Fewer data relate cardiac events to months of the year and season. METHODS AND RESULTS: We analyzed all monthly death certificate data from Los Angeles County, California, for death caused by coronary artery disease from 1985 through 1996 (n=222 265). The mean number of deaths was highest in December at 1808 and January at 1925; the lowest rates were in June, July, August, and September at 1402, 1424, 1418, and 1371, respectively...
October 12, 1999: Circulation
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