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Subramaniam Kuppuswamy, Joshua D Wofford, Chris Joseph, Zhu-Lin Xie, Azim K Ali, Vincent M Lynch, Paul A Lindahl, Michael J Rose
The syntheses, interconversions, and spectroscopic properties of a set of iron carbonyl clusters containing an interstitial carbide are reported. This includes the low temperature X-ray structures of the six-iron clusters (Y)2[Fe6(μ6-C)(μ2-CO)4(CO)12] (1a-c; where Y = NMe4, NEt4, PPh4); the five-iron cluster [Fe5(μ5-C)(CO)15] (3); and the novel formulation of the five-iron cluster (NMe4)2[Fe5(μ5-C)(μ2-CO)(CO)13] (4). Also included in this set is the novel charge-neutral cluster, [Fe6(μ6-C)(CO)18] (2), for which we were unable to obtain a crystallographic structure...
April 25, 2017: Inorganic Chemistry
M A Eftekhar, L G Wright, M S Mills, M Kolesik, R Amezcua Correa, F W Wise, D N Christodoulides
We demonstrate that the pump's spatial input profile can provide additional degrees of freedom in tailoring at will the nonlinear dynamics and the ensuing spectral content of supercontinuum generation in highly multimoded optical fibers. Experiments and simulations carried out at 1550 nm indicate that the modal composition of the input beam can substantially alter the soliton fission process as well as the resulting Raman and dispersive wave generation that eventually lead to supercontinuum in such a multimode environment...
April 17, 2017: Optics Express
Kazuki Yasuhara, Feng Yu, Takaaki Ishigure
We fabricate low-loss single-mode (SM) polymer optical waveguides using a photomask-free simple technique named the Mosquito method. The insertion losses of a 5-cm long SM polymer waveguide fabricated are 2.52 dB and 4.03 dB at 1310- and 1550-nm wavelengths, respectively. The coupling loss between a single-mode fiber and the waveguide is as low as 0.5 dB including the Fresnel reflection. The 0.5-dB misalignment tolerance in the radial direction is ± 2.0 μm at 1550 nm. The Mosquito method is promising for fabricating SM polymer optical waveguides compatible with silicon photonics chips...
April 17, 2017: Optics Express
Naema Othman, Pierre Berini
We propose and investigate a Schottky contact detector where the contact metal is a nanoscale metal stripe waveguide supporting surface plasmons with strong localization along the Schottky contact. We consider Au for the metal stripe, p-doped silicon for the semiconductor, operation in the infrared (at λ<sub>0</sub>=1550  nm), and internal photoemission as the sub-bandgap detection mechanism. We find that the main surface plasmon mode of operation of the Au stripe exhibits diverging real and imaginary parts of n<sub>eff</sub> with decreasing stripe dimensions, commensurate with increasing confinement...
April 20, 2017: Applied Optics
D Ganziy, B Rose, O Bang
We propose a novel type of compact high-resolution multichannel micro-electro-mechanical systems (MEMS)-based interrogator, where we replace the linear detector with a digital micromirror device (DMD). The DMD is typically cheaper and has better pixel sampling than an InGaAs detector used in the 1550 nm range, which leads to cost reduction and better performance. Moreover, the DMD is a 2D array, which means that multichannel systems can be implemented without any additional optical components in the interrogator...
April 20, 2017: Applied Optics
Wee Lit Ng, Wei Ru Wong, Ghafour Amouzad Mahdiraji, Ahmmed A Rifat, Din Chai Tee, Faisal Rafiq Mahamd Adikan
Diamond Ring Fiber (DRF) is proposed to allow a high percentage of evanescent field exposure while maintaining low confinement loss. It provides a long and protected medium for light-matter interaction and large cavities to ease the infiltration of sensing elements. DRFs with different waveguide parameters have been analyzed theoretically and fabricated using a stack-and-draw fiber drawing technique. Mode analysis has been performed experimentally on the fabricated fibers, while the confinement loss and the percentage of evanescent field exposure are examined by simulation...
April 15, 2017: Optics Letters
Chur Kim, Dohyeon Kwon, Dohyun Kim, Sun Young Choi, Sang Jun Cha, Ki Sun Choi, Dong-Il Yeom, Fabian Rotermund, Jungwon Kim
We demonstrate a new planar lightwave circuit (PLC)-based device, integrated with a 980/1550 wavelength division multiplexer, an evanescent-field-interaction-based saturable absorber, and an output tap coupler, which can be employed as a multi-functional element in mode-locked fiber lasers. Using this multi-functional PLC device, we demonstrate a simple, robust, low-noise, and polarization-maintaining mode-locked Er-fiber laser. The measured full-width at half-maximum bandwidth is 6 nm centered at 1555 nm, corresponding to 217 fs transform-limited pulse duration...
April 15, 2017: Optics Letters
Ameneh Bostani, Amirhossein Tehranchi, Raman Kashyap
A specially-designed chirped periodically poled lithium niobate nonlinear crystal was fabricated with a phase-matching bandwidth as large as 50 nm for sum frequency generation to operate at room and higher temperatures. This device also benefits from insensitivity to laser frequency drift and fine alignment. The loosely-focused beam position of a high-power CW laser at around 1550 nm is optimized within the grating for maximum up-conversion efficiency, to realize a super-tunable source in the range of 770-778 nm by tuning a narrowband control signal over 30 nm in the communication band...
April 13, 2017: Scientific Reports
J J M van der Hoeven
OBJECTIVE: The 70-gene signature test (MammaPrint) has been shown to improve prediction of clinical outcome in women with early-stage breast cancer. We sought to provide prospective evidence of the clinical utility of the addition of the 70-gene signature to standard clinical-pathological criteria in selecting patients for adjuvant chemotherapy. METHODS: In this randomized, phase 3 study, we enrolled 6693 women with early-stage breast cancer and determined their genomic risk (using the 70-gene signature) and their clinical risk (using a modified version of Adjuvant! Online)...
2017: Nederlands Tijdschrift Voor Geneeskunde
Hossein Vakili, Henrika Wickström, Diti Desai, Maren Preis, Niklas Sandler
Quality control tools to assess the quality of printable orodispersible formulations are yet to be defined. Four different orodispersible dosage forms containing two poorly soluble drugs, levothyroxine and prednisolone, were produced on two different edible substrates by piezoelectric inkjet printing. Square shaped units of 4cm(2) were printed in different resolutions to achieve an escalating drug dose by highly accurate and uniform displacement of droplets in picoliter range from the printhead onto the substrates...
April 7, 2017: International Journal of Pharmaceutics
Meirav Meiri, Philipp W Stockhammer, Nimrod Marom, Guy Bar-Oz, Lidar Sapir-Hen, Peggy Morgenstern, Stella Macheridis, Baruch Rosen, Dorothée Huchon, Joseph Maran, Israel Finkelstein
The Late Bronze of the Eastern Mediterranean (1550-1150 BCE) was a period of strong commercial relations and great prosperity, which ended in collapse and migration of groups to the Levant. Here we aim at studying the translocation of cattle and pigs during this period. We sequenced the first ancient mitochondrial and Y chromosome DNA of cattle from Greece and Israel and compared the results with morphometric analysis of the metacarpal in cattle. We also increased previous ancient pig DNA datasets from Israel and extracted the first mitochondrial DNA for samples from Greece...
April 6, 2017: Scientific Reports
Hai-Han Lu, Chung-Yi Li, Chun-Ming Ho, Ming-Te Cheng, Xin-Yao Lin, Zih-Yi Yang, Hwan-Wei Chen
A 64 Gb/s four-level pulse amplitude modulation (PAM4) vertical-cavity surface-emitting laser (VCSEL)-based free-space optical (FSO) link with an external light injection scheme is proposed and successfully demonstrated. Experimental results show that the 11.2 GHz VCSEL with an external light injection scheme is sufficiently powerful for 64 Gb/s PAM4 FSO links. This study is the first one that adopts a 1550-nm VCSEL transmitter with an external light injection scheme in a 64 Gb/s PAM4 FSO link. The link performances of the proposed PAM4 VCSEL-based FSO links have been analyzed in real-time in terms of eye diagrams and offline processed by Matlab in terms of bit error rate (BER) performances...
March 6, 2017: Optics Express
Dongquan Li, Zhe Chen, Guanglei Chen, Si Hu, Yiting Wang, Wentao Qiu, Jiangli Dong, Jianhui Yu, Jun Zhang, Jieyuan Tang, Yunhan Luo, Heyuan Guan, Huihui Lu
Reduced graphene oxide (rGO) sheet wrapped on the tapered region of microfiber is demonstrated to enhance the interaction between rGO and strong evanescent field of optical fiber. The 405 nm and 980 nm lasers are employed to illuminate the rGO to investigate the response characteristics of the optical transmitted power (λ = 1550 nm) in the MF. The transmitted optical power of the MF with rGO changes with ~1.7 dB relative variation when the violet light is ranging from 0 mW to 12 mW (~0.21dB/mW) in the outside-pumped experiment...
March 6, 2017: Optics Express
T Martan, T Nemecek, M Komanec, R Ahmad, S Zvanovec
Detecting explosive, flammable, or toxic industrial liquids reliably and accurately is a matter of civic responsibility that cannot be treated lightly. Tapered optical fibers (TOFs) and suspended core microstructured optical fibers (SC MOFs) were separately used as sensors of liquids without being compared to each other. We present a highly sensitive time-stable TOF sensor incorporated in the pipeline system for the in-line regime of measurement. This paper is furthermore focused on the comparison of this TOF and SC MOF of similar parameters for the detection of selected liquids...
March 20, 2017: Applied Optics
Qiang Hao, Guoshen Zhu, Song Yang, Kangwen Yang, Tao Duan, Xiaoping Xie, Kun Huang, Heping Zeng
We report on the experimental implementation of single-frequency fiber-laser pumped mid-infrared (mid-IR) transmitter and receiver modules for free-space communications. These modules enable frequency upconversion and downconversion between the 1550-nm telecom wavelength and the mid-IR, thus providing essential free-space transmission links with mid-IR single-frequency lasers in the 3.6 μm region. Specifically, based on difference frequency generation (DFG) in MgO-doped periodically poled LiNbO<sub>3</sub> (MgO:PPLN), the mid-IR transmitter produces 9...
March 10, 2017: Applied Optics
Jian Gao, Jianfeng Sun, Mingyu Cong
Frequency-modulated/continuous-wave imaging systems are a focal plane array (FPA) ladar architecture that is applicable to smart munitions, reconnaissance, face recognition, robotic navigation, etc. In this paper, we report a 64×64 pixel FPA ladar system we built using a 1550 nm amplified laser diode transmitter and an InAlAs/InGaAs metal-semiconductor-metal self-mixing detector array and the test results attained over the years it was constructed. Finally, we gained 4D imaging (3D range + 1D intensity) of the target with the range of 220 m...
April 1, 2017: Applied Optics
Bryan Zuanetti, Tianxue Wang, Vikas Prakash
While Photonic Doppler Velocimetry (PDV) has become a common diagnostic tool for the measurement of normal component of particle motion in shock wave experiments, this technique has not yet been modified for the measurement of combined normal and transverse motion, as needed in oblique plate impact experiments. In this paper, we discuss the design and implementation of a compact fiber-optics-based heterodyne combined normal and transverse displacement interferometer. Like the standard PDV, this diagnostic tool is assembled using commercially available telecommunications hardware and uses a 1550 nm wavelength 2 W fiber-coupled laser, an optical focuser, and single mode fibers to transport light to and from the target...
March 2017: Review of Scientific Instruments
Petra M Pöllänen, Johanna Lempainen, Antti-Pekka Laine, Jorma Toppari, Riitta Veijola, Paula Vähäsalo, Jorma Ilonen, Heli Siljander, Mikael Knip
AIMS/HYPOTHESIS: In this study, we aimed to characterise rapid progressors to type 1 diabetes among children recruited from the general population, on the basis of HLA-conferred disease susceptibility. METHODS: We monitored 7410 HLA-predisposed children participating in the Finnish Type 1 Diabetes Prediction and Prevention (DIPP) study for the development of beta cell autoimmunity and type 1 diabetes from birth over a median follow-up time of 16.2 years (range 0...
March 31, 2017: Diabetologia
Guigen Liu, Qiwen Sheng, Dustin Dam, Jiong Hua, Weilin Hou, Ming Han
We report a fiber-optic micro-heater based on a miniature crystalline silicon Fabry-Perot interferometer (FPI) fusion spliced to the endface of a single-mode fiber. The silicon FPI, having a diameter of 100 μm and a length of 10 or 200 μm, is heated by a 980 nm laser diode guided through the lead-in fiber, leading to a localized hot spot with a temperature that can be conveniently tuned from the ambient temperature to >1000°C in air. In the meantime, using a white light system operating in the 1550 nm wavelength window where the silicon is transparent, the silicon FPI itself also serves as a thermometer with high resolution and high speed for convenient monitoring and precise control of the heater temperature...
April 1, 2017: Optics Letters
David Garcia-Rodriguez, Juan L Corral, Amadeu Griol, Roberto Llorente
The use of an integrated asymmetrical directional coupler for two-mode transmission at 1550 nm is analyzed. The design is based on silicon-on-insulator (SOI) technology and permits mode conversion and mode multiplexing/demultiplexing. In the nominal design, mode conversion and mode (de)multiplexing are achieved with 97% efficiency and a 23.4 dB crosstalk level in the 1540-1560 nm band using a 0.1 μm gap. The dimension tolerance of the SOI process has been taken into account in the selection of the optimum design, and the coupling efficiency would remain above 82...
April 1, 2017: Optics Letters
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