keyword
https://read.qxmd.com/read/38531885/construction-of-active-inert-core-shell-structured-nanocrystals-for-broad-range-multicolor-upconversion-luminescence
#1
JOURNAL ARTICLE
Mengyao Zhu, Zhenhua Li, Xuecheng Li, Xueru Zhang, Yuxiao Wang, Haoyue Hao, Liang Li
Rare earth doped up-conversion luminescent nano-materials exhibit abundant emission colors under suitable excitation condition. In this work, NaYF4 :Er/Ho@NaYF4 and NaYbF4 :Tm@NaYF4 nanoparticles were synthesized by co-precipitation method. The pure red emission can be realized by the designed NaYF4 :Er/Ho@NaYF4 nanocrystals and the R/Gs reach 23.3 and 25 under excitations of 980 and 1550 nm lasers, respectively. The R/G declines as the power increasing with the emission color changing from red to yellow, which is due to the quick saturation of the energy levels, radiating red emissions...
March 26, 2024: Scientific Reports
https://read.qxmd.com/read/38518919/glycated-albumin-and-adverse-clinical-outcomes-in-patients-with-ckd-a-prospective-cohort-study
#2
JOURNAL ARTICLE
Mengyao Tang, Anders H Berg, Hui Zheng, Eugene P Rhee, Andrew S Allegretti, Sagar U Nigwekar, S Ananth Karumanchi, James P Lash, Sahir Kalim
RATIONALE & OBJECTIVE: HbA1c is widely used to estimate glycemia, yet it is less reliable in patients with chronic kidney disease (CKD). There is growing interest in the complementary use of glycated albumin (GA) to improve glycemic monitoring and risk stratification. However, whether GA associates with clinical outcomes in a non-dialysis dependent CKD population remains unknown. STUDY DESIGN: Prospective cohort study. SETTING: & Participants: 3110 participants with CKD from the Chronic Renal Insufficiency Cohort study...
March 20, 2024: American Journal of Kidney Diseases
https://read.qxmd.com/read/38512334/two-dimensional-molybdenum-boride-mbene-mo-4-3-b-2-t-x-with-broadband-and-termination-dependent-ultrafast-nonlinear-optical-response
#3
JOURNAL ARTICLE
Yiduo Wang, Gang Wang, Yingwei Wang, Li Zhou, Jianlong Kang, Wanxin Zheng, Si Xiao, Guichuan Xing, Jun He
Two-dimensional molybdenum borides (MBenes) comprise a new class of 2D transition metal borides that exhibit potential photonics applications. Recently, the synthesis of individual single-layer Mo4/3 B2 T x (T = O, F, OH) MBene sheets has been realized, which attracted considerable attention in optoelectronics. However, there is still a lack of understanding and regulation of the photophysical processes of Mo4/3 B2 T x MBene. Here, we demonstrate that Mo4/3 B2 T x MBene exhibits a surface termination-dependent electronic structure, carrier dynamics, and nonlinear optical response over a wide wavelength range (500-1550 nm)...
March 21, 2024: Journal of Physical Chemistry Letters
https://read.qxmd.com/read/38507509/overview-of-the-evolution-of-hypertension-from-ancient-chinese-emperors-to-today
#4
REVIEW
George L Bakris, Michael A Weber
Hypertension is one of the most commonly treated conditions in modern medical practice, but despite its long history, it was largely ignored until the midpoint of the 20th century. This article will review the origins of elevated blood pressure from when it was first appreciated in 2600 BC to its most recent emerging treatments. Awareness of sustained elevations in blood pressure goes back to the Chinese Yellow Emperor's Classic of Internal Medicine (2600 BC); even then, salt was appreciated as a contributor to elevated pressure...
April 2024: Hypertension
https://read.qxmd.com/read/38507487/ultralow-loss-optical-interconnect-enabled-by-topological-unidirectional-guided-resonance
#5
JOURNAL ARTICLE
Haoran Wang, Yi Zuo, Xuefan Yin, Zihao Chen, Zixuan Zhang, Feifan Wang, Yuefeng Hu, Xiaoyu Zhang, Chao Peng
Grating couplers that interconnect photonic chips to off-chip components are crucial for various optoelectronics applications. Despite numerous efforts in past decades, the existing grating couplers are still far from optimal in energy efficiency and thus hinder photonic integration toward a larger scale. Here, we propose a strategy to achieve ultralow-loss grating couplers by using unidirectional guided resonances (UGRs), suppressing the useless downward radiation with no mirror on the bottom. By engineering the dispersion and apodizing the geometry of grating, we experimentally realize a grating coupler with a record-low loss of -0...
March 22, 2024: Science Advances
https://read.qxmd.com/read/38504512/wide-spectrum-of-novel-and-rare-hemoglobin-variants-in-the-multi-ethnic-indian-population-a-review
#6
REVIEW
Pallavi Thaker, Namrata Mahajan, Malay B Mukherjee, Roshan B Colah
The hemoglobin (Hb) variants are qualitative abnormalities due to production of structurally abnormal globin proteins. They are categorized based on the type of mutation present in the α1, α2, β, Gγ, Aγ and δ globin genes. So far, more than 1550 Hb variants are reported in the database. They could lead to Hb polymerization, Hb instability, altered oxygen affinity and decreased oxygen-carrying capacity of Hb or have no clinical manifestations. In India, ethnic diversity, consanguinity, regional variations and migration result in the presence of different Hb variants...
March 19, 2024: International Journal of Laboratory Hematology
https://read.qxmd.com/read/38502198/cardiovascular-events-reported-in-patients-with-b-cell-malignancies-treated-with-zanubrutinib
#7
JOURNAL ARTICLE
Javid J Moslehi, Richard R Furman, Constantine S Tam, Joe-Elie Salem, Christopher R Flowers, Aileen Cohen, Meng Zhang, Jun Zhang, Lipeng Chen, Han Ma, Jennifer R Brown
First-generation Bruton tyrosine kinase (BTK) inhibitor ibrutinib has been associated with an increased risk for cardiovascular toxicities. Zanubrutinib is a more selective, next-generation BTK inhibitor. In this manuscript, incidence rates of atrial fibrillation, symptomatic (grade ≥2) ventricular arrhythmia, and hypertension were evaluated in a pooled analysis of 10 clinical studies with zanubrutinib monotherapy in patients (N=1550) with B-cell malignancies and a pooled analysis of head-to-head studies comparing zanubrutinib with ibrutinib (ASPEN cohort 1; ALPINE)...
March 19, 2024: Blood Advances
https://read.qxmd.com/read/38494882/the-novel-hla-dpb1-1550-01-allele-identified-by-sanger-dideoxy-nucleotide-sequencing-in-a-chinese-individual
#8
JOURNAL ARTICLE
Zheng-Fa Li, Zhi-Cong Xie, Li Ma, Ye-Mo Li, Ting Dong
HLA-DPB1*1550:01 differs from HLA-DPB1*02:02:01:01 by one nucleotide in exon 2.
March 2024: HLA
https://read.qxmd.com/read/38491065/lanthanide-luminescence-nanothermometer-with-working-wavelength-beyond-1500%C3%A2-nm-for-cerebrovascular-temperature-imaging-in-vivo
#9
JOURNAL ARTICLE
Yukai Wu, Fang Li, Yanan Wu, Hao Wang, Liangtao Gu, Jieying Zhang, Yukun Qi, Lingkai Meng, Na Kong, Yingjie Chai, Qian Hu, Zhenyu Xing, Wuwei Ren, Fuyou Li, Xingjun Zhu
Nanothermometers enable the detection of temperature changes at the microscopic scale, which is crucial for elucidating biological mechanisms and guiding treatment strategies. However, temperature monitoring of micron-scale structures in vivo using luminescent nanothermometers remains challenging, primarily due to the severe scattering effect of biological tissue that compromises the imaging resolution. Herein, a lanthanide luminescence nanothermometer with a working wavelength beyond 1500 nm is developed to achieve high-resolution temperature imaging in vivo...
March 15, 2024: Nature Communications
https://read.qxmd.com/read/38489875/effects-of-synergistic-modification-using-alkalis-and-guar-gum-on-the-pasting-rheological-and-microstructural-properties-of-germinated-highland-barley-starch-gels
#10
JOURNAL ARTICLE
Wentao Pan, Xin Qi, Mingyue Shen, Yi Chen, Qiang Yu, Zhibing Huang, Jianhua Xie
Germination treatment of highland barley enhances its nutritional value while weakening the starch gel properties. This study aims to enhance the characteristics of germinated highland barley starch (GBS) by exploring the synergistic effects of two alkalis (Na2 CO3 and NaHCO3 ) and guar gum (GG) on GBS gel properties. The combined action of alkalis and GG significantly improved the peak viscosity, setback viscosity, and hardness compared with GG alone. The highest G' and G" reached 998 and 204 Pa at 0...
March 11, 2024: Food Chemistry
https://read.qxmd.com/read/38489807/influence-of-socioeconomic-status-on-clinical-outcomes-of-diffuse-midline-glioma-and-diffuse-intrinsic-pontine-glioma
#11
JOURNAL ARTICLE
John H Lee, Katherine G Holste, Momodou G Bah, Andrea T Franson, Hugh J L Garton, Cormac O Maher, Karin M Muraszko
OBJECTIVE: Given the lack of a definitive treatment and the poor prognosis of patients with diffuse midline glioma (DMG) and diffuse intrinsic pontine glioma (DIPG), socioeconomic status (SES) may affect treatment access and therefore survival. Therefore, this study aimed to examine the relationship between SES and treatment modalities, progression-free survival (PFS), and overall survival (OS) in children with DMG/DIPG. METHODS: A retrospective, single-institution review was conducted of medical records of patients ≤ 18 years of age who had DMG or DIPG that was diagnosed between 2000 and 2022...
March 15, 2024: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/38489452/coverage-extended-mmf-based-indoor-owc-using-overfilled-launch-and-diversity-reception
#12
JOURNAL ARTICLE
Jin Shi, Yuzhe Wang, Xinda Yan, Zhengying Li, Eduward Tangdiongga
Speckle patterns generated as coherent optical beams are reflected by scattering elements. Multimode fibers (MMFs) can modify the transverse intensity distribution of speckle patterns with macro perturbations, i.e., pressures, providing a simple and low-cost way to achieve equivalent beam-steering for indoor optical wireless communications (OWCs) with divergent optical beams. However, the received optical power (ROP) variance severely limits the mobility of user terminals. In this paper, the issue is alleviated by using the overfilled launch of MMFs and the diversity gain of multi-receivers...
March 15, 2024: Optics Letters
https://read.qxmd.com/read/38489434/wavelength-conversion-through-stimulated-raman-scattering-in-an-oxygen-filled-fiber-for-multi-band-lidar
#13
JOURNAL ARTICLE
Micah Raab, Daniel Leaird, Trevor L Courtney, Christian Keyser, Rodrigo Amezcua Correa
Wavelength conversion afforded by stimulated Raman scattering within a hollow core fiber is potentially useful for multispectral light detection and ranging (LiDAR). Herein, we make use of the ideal 1550 cm-1 vibrational Raman shift of an antiresonant fiber filled with gaseous oxygen so that the first and second Raman orders as well as the transmitted pump are all located in separate atmospheric transmission windows. To the best of our knowledge, this is the first report of stimulated Raman scattering in an oxygen-filled fiber...
March 15, 2024: Optics Letters
https://read.qxmd.com/read/38489428/high-efficiency-narrow-bandwidth-ktp-optical-parametric-oscillator-for-khz-mhz-planar-laser-induced-fluorescence
#14
JOURNAL ARTICLE
Austin M Webb, Christopher Q Crabtree, Venkat Athmanathan, Terrence R Meyer, Sean P Kearney, Mikhail N Slipchenko
The electronic excitation of key combustion species or flow tagging of chemical species requires a narrowband tunable UV source. In this work, a potassium titanyl phosphate (KTP) burst-mode optical parametric oscillator (OPO) pumped by a 532 nm laser is developed to generate a spectrally narrow signal and an idler output with 1.48 ± 0.19 cm-1 bandwidth without the need for injection seeding. The idler (1410-1550 nm range) is further mixed with 355 or 266 nm to generate 284 or 226 nm for OH or NO planar laser-induced fluorescence (PLIF), respectively, with up to 1...
March 15, 2024: Optics Letters
https://read.qxmd.com/read/38482833/vibrational-anisotropy-decay-resolves-rare-earth-binding-induced-conformational-change-in-dtpa
#15
JOURNAL ARTICLE
Ranadeb Ball, Jessica A Jackson, Tomekia Simeon, George C Schatz, Jenifer C Shafer, Jessica M Anna
Elucidating the relationship between metal-ligand interactions and the associated conformational change of the ligand is critical for understanding the separation of lanthanides via ion binding. Here we examine DTPA, a multidentate ligand that binds lanthanides, in its free and metal bound conformations using ultrafast polarization dependent vibrational spectroscopy. The polarization dependent pump-probe spectra were analyzed to extract the isotropic and anisotropic response of DTPA's carbonyl groups in the 1550-1650 cm-1 spectral region...
March 14, 2024: Physical Chemistry Chemical Physics: PCCP
https://read.qxmd.com/read/38480029/maternal-mortality-in-the-united-states-are-the-high-and-rising-rates-due-to-changes-in-obstetrical-factors-maternal-medical-conditions-or-maternal-mortality-surveillance
#16
JOURNAL ARTICLE
K S Joseph, Sarka Lisonkova, Amélie Boutin, Giulia M Muraca, Neda Razaz, Sid John, Yasser Sabr, Wee-Shian Chan, Azar Mehrabadi, Justin S Brandt, Enrique F Schisterman, Cande V Ananth
BACKGROUND: National Vital Statistics System reports show that maternal mortality rates in the United States have nearly doubled, from 17.4 in 2018 to 32.9 per 100,000 live births in 2021. However, these high and rising rates could reflect issues unrelated to obstetrical factors, such as changes in maternal medical conditions or maternal mortality surveillance (eg, due to introduction of the pregnancy checkbox). OBJECTIVE: This study aimed to assess if the high and rising rates of maternal mortality in the United States reflect changes in obstetrical factors, maternal medical conditions, or maternal mortality surveillance...
February 29, 2024: American Journal of Obstetrics and Gynecology
https://read.qxmd.com/read/38477492/clinical-value-of-endoscopic-ultrasound-sound-speed-in-differential-diagnosis-of-pancreatic-solid-lesion-and-prognosis-of-pancreatic-cancer
#17
JOURNAL ARTICLE
Jianing Qiu, Kangrong Li, Xiuyan Long, Xiaoyu Yu, Pan Gong, Yu Long, Xiaoyan Wang, Li Tian
BACKGROUND: Differential diagnosis of pancreatic solid lesion (PSL) and prognosis of pancreatic cancer (PC) is a clinical challenge. We aimed to explore the differential diagnostic value of sound speed (SS) obtained from endoscopic ultrasonography (EUS) in PSL and the prognostic value of SS in PC. METHODS: Patients with PSL in The Third Xiangya Hospital of Central South University from March 2019 to October 2019 were prospectively enrolled, who obtained SS from PSL...
March 2024: Cancer Medicine
https://read.qxmd.com/read/38470731/two-structural-designs-of-broadband-low-loss-and-compact-tm-magneto-optical-isolator-based-on-gaas-on-insulator
#18
JOURNAL ARTICLE
Li Liu, Wan-Ting Chen, Jia Zhao, Chen Zhang
Integrated optical isolators are important building blocks for photonic integrated chips. Despite significant advances in isolators integrated on silicon-on-insulator (SOI) platforms, integrated isolators on GaAs-on-insulator platforms are rarely reported. In this paper, two structural designs of optical isolators based on the TM basic mode of GaAs-on-insulator are proposed. The non-reciprocal phase shift (NRPS) of GaAs/Ce:YIG waveguides with different geometric structures are calculated using numerical simulation...
February 21, 2024: Nanomaterials
https://read.qxmd.com/read/38468008/green-synthesis-of-carbon-quantum-dots-from-teak-leaves-biomass-for-in-situ-precipitation-and-regenerative-removal-of-methylene-blue-dye
#19
JOURNAL ARTICLE
Zakriya Waseem Basha, Annamalai Senthil Kumar, Sarangapani Muniraj
The objective of this study was to completely eliminate environmentally harmful cationic organic dye from aqueous solutions using the one-step ultrasonication method, renowned for its energy efficiency, user-friendliness, and minimal requirement for chemical resources, making it particularly suitable for large-scale applications. To achieve effective environmental remediation, we employed carbon dots derived from teak leaf biomass (TBCDs) layered with graphene oxide. We conducted a thorough characterization of the TBCDs using UV-vis spectroscopy (with absorption peaks at λmax  = 208 and 276 nm), FTIR spectroscopy (confirming the presence of various functional groups including -OH, -CH, C = O, COO- , C-O-C, and = C-H), Raman spectroscopy (with bands at 1369 cm-1 (D-Band) and 1550 cm-1 (G-Band), and an intensity ratio (ID /IG ) = 0...
March 11, 2024: Environmental Science and Pollution Research International
https://read.qxmd.com/read/38462625/safety-and-tolerability-of-atogepant-for-the-preventive-treatment-of-migraine-a-post-hoc-analysis-of-pooled-data-from-four-clinical-trials
#20
RANDOMIZED CONTROLLED TRIAL
Paul Rizzoli, Michael J Marmura, Jennifer Robblee, Jennifer McVige, Sara Sacco, Stephanie J Nahas, Jessica Ailani, Rosa De Abreu Ferreira, Julia Ma, Jonathan H Smith, Brett Dabruzzo, Messoud Ashina
BACKGROUND: Conventional, non-specific preventive migraine treatments often demonstrate low rates of treatment persistence due to poor efficacy or tolerability. Effective, well-tolerated preventive treatments are needed to reduce migraine symptoms, improve function, and enhance quality of life. Atogepant is a migraine-specific oral calcitonin gene-related peptide receptor antagonist that is indicated for the preventive treatment of migraine in adults. This analysis evaluated the safety and tolerability profile of atogepant for the preventive treatment of migraine, including adverse events (AEs) of interest, such as constipation, nausea, hepatic safety, weight changes, and cardiac disorders...
March 11, 2024: Journal of Headache and Pain
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