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https://www.readbyqxmd.com/read/28730086/peptidome-profiling-of-human-serum-of-uveal-melanoma-patients-based-on-magnetic-bead-fractionation-and-mass-spectrometry
#1
Xiang-Yu Shi, Qing Li, Wen-Bin Wei, Li-Ming Tao
AIM: To find new biomarkers for uveal melanoma (UM) by analyzing the serum peptidome profile. METHODS: Proteomic spectra in patients with UM before and after operation were analyzed and compared with those of healthy controls. Magnetic affinity beads were used to capture serum peptides and matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometer were used to compile serum peptide profiles. RESULTS: A panel of 49 peptides were differentially expressed between UM patients and controls, of which 33 peptides were of higher intensities in patient group and 16 peptides were of higher intensities in control group...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28710660/fractional-er-yag-laser-assisting-topical-betamethasone-solution-in-combination-with-nb-uvb-for-resistant-non-segmental-vitiligo
#2
Ru Yan, Jinping Yuan, Hongqiang Chen, Yuan-Hong Li, Yan Wu, Xing-Hua Gao, Hong-Duo Chen
Resistant non-segmental vitiligo is difficult to be treated. Ablative erbium-YAG (Er:YAG) laser has been used in the treatment of vitiligo, but the ablation of entire epidermis frustrated the compliance of patients. The purpose of this study is to investigate the effects of fractional Er:YAG laser followed by topical betamethasone and narrow band ultraviolet B (NB-UVB) therapy in the treatment of resistant non-segmental vitiligo. The vitiligo lesions of each enrolled patient were divided into four treatment parts, which were all irradiated with NB-UVB...
July 14, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28709940/investigation-of-l-leucine-in-reducing-the-moisture-induced-deterioration-of-spray-dried-salbutamol-sulfate-power-for-inhalation
#3
Liang Li, Sharon Shui Yee Leung, Thomas Gengenbach, Jiaqi Yu, Ge Fiona Gao, Patricia Tang, Qi Tony Zhou, Hak-Kim Chan
The aim of this study was to investigate the ability of L-leucine (LL) in preventing moisture-induced deterioration in the in vitro aerosolization performance of spray-dried (SD) salbutamol sulfate (SS). Increasing mass fraction of LL (5-80%) were co-spray dried with SS, and the physicochemical properties of the powders were characterized by laser diffraction, X-ray powder diffraction (XRD) and dynamic vapour sorption (DVS). Furthermore, the surface morphology and chemistry of fine particles was analyzed by scanning electron microscopy (SEM) and X-ray photoelectron spectroscopy (XPS)...
July 11, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28707932/1-5%C3%A2-%C3%A2-%C3%AE-m-lasers-with-sub-10%C3%A2-mhz-linewidth
#4
D G Matei, T Legero, S Häfner, C Grebing, R Weyrich, W Zhang, L Sonderhouse, J M Robinson, J Ye, F Riehle, U Sterr
We report on two ultrastable lasers each stabilized to independent silicon Fabry-Pérot cavities operated at 124 K. The fractional frequency instability of each laser is completely determined by the fundamental thermal Brownian noise of the mirror coatings with a flicker noise floor of 4×10^{-17} for integration times between 0.8 s and a few tens of seconds. We rigorously treat the notorious divergences encountered with the associated flicker frequency noise and derive methods to relate this noise to observable and practically relevant linewidths and coherence times...
June 30, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28702061/the-effect-of-surface-treatment-with-a-fractional-carbon-dioxide-laser-on-shear-bond-strength-of-resin-cement-to-a-lithium-disilicate-based-ceramic
#5
Farzaneh Ahrari, Alireza Boruziniat, Hamideh Sadat Mohammadipour, Mehrnoosh Alirezaei
BACKGROUND: This study investigated the impact of different surface treatments, including fractional carbon dioxide (CO2) laser on shear bond strength (SBS) of resin cement to lithium disilicate ceramic. MATERIALS AND METHODS: In this in vitro study, 72 blocks of IPS e.max CAD ceramic were randomly divided into six groups in terms of treatment (n = 12). Group 1 underwent etching with 9.6% hydrofluoric (HF) acid, whereas group 2 was subjected to air abrasion with aluminum oxide particles...
May 2017: Dental Research Journal
https://www.readbyqxmd.com/read/28697226/randomized-split-face-d%C3%A3-collet%C3%A3-comparative-trial-of-procedure-enhancement-system-for-fractional-non-ablative-laser-resurfacing-treatment
#6
Deanne Mraz Robinson, Ashton P Frulla
<p>INTRODUCTION: A topical proprietary procedural enhancement system (PES) containing a combination of active ingredients including a tripeptide and hexapeptide (TriHex Technology™, Alastin Procedure Enhancement Invasive System, ALASTIN Skincare™, Inc., Carlsbad, CA) has been used successfully to aid in healing and improve symptomatology following resurfacing procedures.</p> <p>METHODS: PES (Gentle Cleanser, Regenerating Skin Nectar with TriHex Technology™, Ultra Nourishing Moisturizer with TriHex Technology™, Soothe + Protect Recovery Balm, Broad Spectrum 30+ Sunscreen) was compared to a basic regimen (Aquaphor™, Cerave™ cleanser, Vanicream™, Alastin Broad Spectrum 30+ Sunscreen) in a split face/ décolleté trial following fractional non-ablative thulium-doped resurfacing treatment to the face or décolleté...
July 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28693425/cyclic-pao2-oscillations-assessed-in-the-renal-microcirculation-correlation-with-tidal-volume-in-a-porcine-model-of-lung-lavage
#7
Rainer Thomas, Christian Möllmann, Alexander Ziebart, Tanghua Liu, Matthias David, Erik K Hartmann
BACKGROUND: Oscillations of the arterial partial pressure of oxygen induced by varying shunt fractions occur during cyclic alveolar recruitment within the injured lung. Recently, these were proposed as a pathomechanism that may be relevant for remote organ injury following acute respiratory distress syndrome. This study examines the transmission of oxygen oscillations to the renal tissue and their tidal volume dependency. METHODS: Lung injury was induced by repetitive bronchoalveolar lavage in eight anaesthetized pigs...
July 11, 2017: BMC Anesthesiology
https://www.readbyqxmd.com/read/28692353/fractional-carbon-dioxide-co2-laser-combined-with-topical-tretinoin-for-the-treatment-of-different-forms-of-cystic-acne
#8
Carmela Pestoni Porvén, Vanessa Vieira Dos Santos, Jesus Del Pozo Losada
Nodulocystic acne is prone to scarring and difficult to treat with treatments other than oral isotretinoin. The aim of this article is to discuss the role of a single session of a fractional CO2 laser combined with a topical treatment with a tretinoin and antibiotic gel for a month as a successful treatment to improve nodulocystic acne and chronic microcystic acne. Two cases were involved: the first with nodulocystic acne lesions that persisted after oral retinoids and the second with chronic microcystic acne resistant to topical treatments...
July 10, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/28688260/soil-aggregate-stability-and-size-selective-sediment-transport-with-surface-runoff-as-affected-by-organic-residue-amendment
#9
Pu Shi, Christian Arter, Xingyu Liu, Martin Keller, Rainer Schulin
Aggregate breakdown influences the availability of soil particles for size-selective sediment transport with surface runoff during erosive rainfall events. Organic matter management is known to affect aggregate stability against breakdown, but little is known about how this translates into rainfall-induced aggregate fragmentation and sediment transport under field conditions. In this study, we performed field experiments in which artificial rainfall was applied after pre-wetting on three pairs of arable soil plots (1...
July 5, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28687935/update-of-ablative-fractionated-lasers-to-enhance-cutaneous-topical-drug-delivery
#10
REVIEW
Jill S Waibel, Ashley Rudnick, Deborah R Shagalov, Danielle M Nicolazzo
Ablative fractional lasers (AFXL) enhance uptake of therapeutics and this newly emerging field is called laser-assisted drug delivery (LAD). This new science has emerged over the past decade and is finding its way into clinical practice. LAD is poised to change how medicine delivers drugs. Topical and systemic application of pharmaceutical agents for therapeutic effect is an integral part of medicine. With topical therapy, the stratum corneum barrier of the skin impairs the ability of drugs to enter the body...
July 7, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/28684844/distributed-quasi-bragg-beam-splitter-in-crossed-atomic-waveguides
#11
V Guarrera, R Moore, A Bunting, T Vanderbruggen, Y B Ovchinnikov
We perform an experimental and theoretical study of a novel distributed quasi-Bragg splitter for cold atoms propagating in crossed optical waveguides. The atoms are guided by horizontal red-detuned laser beams which cross with an angle of roughly 90°. The lattice formed by the interference between the two waveguides is used as a quasi-Bragg splitter to continuously deflect the atomic flux from one waveguide into the other. In the limit of strong waveguide confinement and depending on the velocity of the cloud, three main regimes are observed corresponding (1) to the absence of reflection, (2) to partial reflection and (3) to full reflection into the second waveguide...
July 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28681639/development-of-a-field-deployable-method-for-simultaneous-real-time-measurements-of-the-four-most-abundant-n2o-isotopocules
#12
Erkan Ibraim, Eliza Harris, Simon Eyer, Béla Tuzson, Lukas Emmenegger, Johan Six, Joachim Mohn
Understanding and quantifying the biogeochemical cycle of N2O is essential to develop effective N2O emission mitigation strategies. This study presents a novel, fully automated measurement technique that allows simultaneous, high-precision quantification of the four main N2O isotopocules ((14)N(14)N(16)O, (14)N(15)N(16)O, (15)N(14)N(16)O and (14)N(14)N(18)O) in ambient air. The instrumentation consists of a trace gas extractor (TREX) coupled to a quantum cascade laser absorption spectrometer, designed for autonomous operation at remote measurement sites...
July 6, 2017: Isotopes in Environmental and Health Studies
https://www.readbyqxmd.com/read/28669773/development-of-a-methodological-approach-for-the-characterization-of-bioaerosols-in-exhaust-air-from-pig-fattening-farms-with-maldi-tof-mass-spectrometry
#13
Katharina Druckenmüller, Andrea Gärtner, Udo Jäckel, Kerstin Klug, Johannes Schiffels, Klaus Günther, Gereon Elbers
In this paper, we evaluated matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) as a cultivation-independent, routinely applicable approach to identify microbial fractions in bioaerosol emission samples. We developed a streamlined protocol in line with the German state-of-the-art impingement sampling guideline. Following isokinetic sampling, a fast and reliable pre-treatment methodology involving a series of cascade filtration steps was implemented, which produced fractions for spectrometric measurement devoid of interfering substances...
May 11, 2017: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/28665161/long-term-results-of-the-treatment-of-pregnancy-induced-striae-distensae-using-a-1550-nm-non-ablative-fractional-laser
#14
Hilal Gokalp
BACKGROUND: Striae distensae (SD) are a type of dermal scarring that is quite common and difficult to treat. Two forms are known: striae rubrae (SR) and striae albae (SA). OBJECTIVE: We evaluated and compared the long-term clinical effectiveness of SR and SA treatment using a 1550-nm non-ablative fractional laser (NAFL). MATERIALS AND METHODS: We included 16 female patients (8 with SR and 8 with SA) who had developed abdominal SD during pregnancy...
June 30, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/28662298/advanced-film-forming-gel-formula-vs-spring-thermal-water-and-white-petrolatum-as-primary-dressings-after-full-face-ablative-fractional-co2-laser-resurfacing-a-comparative-split-face-pilot-study
#15
Leonardo Marini
BACKGROUND: Aesthetically pleasing results and fast, uneventful recovery are highly desirable after rejuvenating ablative laser procedures. Wound dressings following ablative laser procedures should ideally improve and optimize the wound healing environment. OBJECTIVE: The purpose of this comparative split face, single blinded, prospective observational study was to assess the efficacy and acceptability of two primary wound dressings immediately after a full face fractional CO2 laser resurfacing procedure...
June 29, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28658462/isotretinoin-and-timing-of-procedural-interventions-a-systematic-review-with-consensus-recommendations
#16
Leah K Spring, Andrew C Krakowski, Murad Alam, Ashish Bhatia, Jeremy Brauer, Joel Cohen, James Q Del Rosso, Lucia Diaz, Jeffrey Dover, Lawrence F Eichenfield, Geoffrey C Gurtner, C William Hanke, Marla N Jahnke, Kristen M Kelly, Shilpi Khetarpal, Megan A Kinney, Moise L Levy, James Leyden, Michael T Longaker, Girish S Munavalli, David M Ozog, Heidi Prather, Peter R Shumaker, Elizabeth Tanzi, Abel Torres, Mara Weinstein Velez, Abigail B Waldman, Albert C Yan, Andrea L Zaenglein
Importance: The notion that systemic isotretinoin taken within 6 to 12 months of cutaneous surgery contributes to abnormal scarring or delayed wound healing is widely taught and practiced; however, it is based on 3 small case series from the mid-1980s. Objective: To evaluate the body of literature to provide evidence-based recommendations regarding the safety of procedural interventions performed either concurrently with, or immediately following the cessation of systemic isotretinoin therapy...
June 28, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28658179/ablative-fractional-laser-resurfacing-with-laser-assisted-delivery-of-5-fluorouracil-for-the-treatment-of-cicatricial-ectropion-and-periocular-scarring
#17
Bradford W Lee, Alexandra E Levitt, Benjamin P Erickson, Audrey C Ko, Neda Nikpoor, Nisreen Ezuddin, Wendy W Lee
PURPOSE: Cicatricial ectropion and periocular scarring can cause significant functional and cosmetic deficits. Surgical treatments can be associated with recicatrization, donor site morbidity, and textural and pigmentary abnormalities. This case series reports on efficacy and safety of a novel nonsurgical approach to treating cicatricial ectropion using ablative fractional laser resurfacing and laser-assisted delivery of 5-fluorouracil. METHODS: A retrospective review was conducted of all patients at a single institution who received ≥3 rounds of ablative fractional laser resurfacing with laser-assisted delivery of 5-fluorouracil...
June 27, 2017: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28655664/protection-of-hydrophobic-amino-acids-against-moisture-induced-deterioration-in-the-aerosolization-performance-of-highly-hygroscopic-spray-dried-powders
#18
Jiaqi Yu, Hak-Kim Chan, Thomas Gengenbach, John A Denman
BACKGROUND: Inhalable particles containing amorphous form of drugs or excipients may absorb atmospheric moisture, causing powder aggregation and recrystallization, adversely affecting powder dispersion and lung deposition. The present study aims to explore hydrophobic amino acids for protection against moisture in spray-dried amorphous powders, using disodium cromoglycate (DSCG) as a model drug. MATERIALS AND METHODS: DSCG powders were produced by co-spray drying with isoleucine (Ile), valine (Val) and methionine (Met) in various concentrations (10, 20 and 40% w/w)...
June 24, 2017: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/28648437/utility-of-adjunctive-modalities-in-coronary-chronic-total-occlusion-intervention
#19
REVIEW
Hemal Bhatt, Sean Janzer, Jon C George
Coronary chronic total occlusion (CTO) intervention remains one of the most challenging domains in interventional cardiology. Due to the technical challenges involved and potential procedural complications, CTO percutaneous coronary intervention (PCI) attempt and success rates remain less than standard PCI. However, the use of several adjunctive tools such as intravascular ultrasound, optical coherence tomography, rotational atherectomy, orbital atherectomy, excimer laser coronary atherectomy and percutaneous left ventricular assist device may contribute to improved CTO PCI success rates or provide better hemodynamic assessment of CTO lesion (i...
May 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/28647617/photodynamic-therapy-with-epidermal-ablation-using-fractional-co2-laser-for-treating-superficial-basal-cell-carcinoma-a-case-series
#20
Jae Min Sung, You Chan Kim
No abstract text is available yet for this article.
June 21, 2017: Photodiagnosis and Photodynamic Therapy
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