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https://www.readbyqxmd.com/read/29786454/serum-cystatin-c-as-an-early-predictor-of-acute-kidney-injury-in-preterm-neonates-with-respiratory-distress-syndrome
#1
Tarek Mohey El-Gammacy, Dina Mohamed Shinkar, Noha Refaat Mohamed, Amany Rasmy Al-Halag
Preterm neonates with respiratory distress syndrome (RDS) are at increased risk of acute kidney injury (AKI). Our study aimed at determining whether serum cystatin C (sCysC) on day 3 of life (D3) can early predict AKI in preterm neonates with RDS. This prospective study was conducted on 75 preterm neonates; 50 with RDS and 25 without RDS. On D3, sCysC, serum creatinine (sCr) and blood urea nitrogen (BUN) were measured and estimated glomerular filtration rate (eGFR) was calculated. sCr and BUN levels were measured again on days 5 and 7...
May 22, 2018: Scandinavian Journal of Clinical and Laboratory Investigation
https://www.readbyqxmd.com/read/29781454/nurse-navigator-core-competencies-an-update-to-reflect-the-evolution-of-the-role
#2
Kristen Baileys, Lori McMullen, Barbara Lubejko, Deborah Christensen, Pamela J Haylock, Traudi Rose, Jean Sellers, Dominique Srdanovic
BACKGROUND: The Oncology Nursing Society published Oncology Nurse Navigator (ONN) Core Competencies in 2013. However, a 2016 role delineation study (RDS) indicated that the role had evolved since their release. The RDS also indicated that a growing number of nurse navigators have extensive oncology and navigation experience. OBJECTIVES: The update to the competencies was undertaken to identify current responsibilities of ONNs and differentiate novice from expert practice...
June 1, 2018: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/29780772/the-trends-and-risk-factors-to-predict-adverse-outcomes-in-gestational-diabetes-mellitus-a-10-year-experience-from-2006-to-2015-in-a-single-tertiary-center
#3
Minji Kim, Juyoung Park, Soo Hyun Kim, Yoo Min Kim, Cheonga Yee, Suk-Joo Choi, Soo-Young Oh, Cheong-Rae Roh
Objective: To investigate the change of maternal characteristics, delivery and neonatal outcomes in gestational diabetes mellitus (GDM) over recent 10 years and to identify the risk factors associated with adverse outcome. Methods: Consecutive GDM patients (n=947) delivered in our institution were included. Research period was arbitrarily divided into 2 periods (period 1: from 2006 to 2010, period 2: from 2011 to 2015). Multiple pregnancies or preexisting diabetes were excluded...
May 2018: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/29775707/in-vitro-digestibility-of-normal-and-waxy-corn-starch-is-modified-by-the-addition-of-tween-80
#4
E J Vernon-Carter, J Alvarez-Ramirez, L A Bello-Perez, A Garcia-Hernandez, C Roldan-Cruz, S Garcia-Diaz
Aqueous dispersions of normal and waxy corn starch (3% w/w) were mixed with Tween 80 (0, 7.5, 15, 22.5 and 30 g/100 g of starch), and gelatinized (90 °C, 20 min). Optical microscopy of the gelatinized starch dispersions (GSDx ; x = Tween 80 concentration) revealed that the microstructure was characterized by a continuous phase of leached amylose and amylopectin entangled chains, and a dispersed phase of insoluble remnants, called ghosts, on whose surface small granules were observed, imputed to Tween 80...
May 15, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29771368/restless-sleep-disorder-in-children-a-pilot-study-on-a-tentative-new-diagnostic-category
#5
Lourdes M DelRosso, Oliviero Bruni, Raffaele Ferri
Study Objectives: A group of children with "restless sleep" who do not fit the criteria for any other sleep disorder but with daytime impairment are studied to identify restless sleep disorder (RSD) clinically and polysomnographically and to differentiate it from other sleep disorders of childhood. Methods: A pilot study of 15 school aged children with restless sleep and 15 sex and age matched children with restless leg syndrome (RLS) and 37 normal controls were included...
May 16, 2018: Sleep
https://www.readbyqxmd.com/read/29762272/differences-in-experiences-with-care-between-homeless-and-nonhomeless-patients-in-veterans-affairs-facilities-with-tailored-and-nontailored-primary-care-teams
#6
Audrey L Jones, Leslie R M Hausmann, Stefan Kertesz, Ying Suo, John P Cashy, Maria K Mor, James H Schaefer, Adi V Gundlapalli, Adam J Gordon
BACKGROUND: Homeless patients describe poor experiences with primary care. In 2012, the Veterans Health Administration (VHA) implemented homeless-tailored primary care teams (Homeless Patient Aligned Care Team, HPACTs) that could improve the primary care experience for homeless patients. OBJECTIVE: To assess differences in primary care experiences between homeless and nonhomeless Veterans receiving care in VHA facilities that had HPACTs available (HPACT facilities) and in VHA facilities lacking HPACTs (non-HPACT facilities)...
May 12, 2018: Medical Care
https://www.readbyqxmd.com/read/29762231/surfactant-administration-during-pediatric-cardiac-extracorporeal-membrane-oxygenation
#7
Constantinos Chrysostomou, Timothy Maul, Filip Istvanic, Peter Wearden
We investigated the safety and efficacy of surfactant during extracorporeal membrane oxygenation (ECMO) in children with cardiac disease. ECMO patients administered surfactant (surfactant group) were compared with patients who did not receive (control). Criteria to administer surfactant were based on a decreased lung compliance of <0.5 ml/kg/cm H2O. Efficacy was determined on pulmonary compliance change and the radiography-based respiratory distress severity (RDS) score. For the surfactant group, lung compliance measurements and RDS scores were obtained just before the first surfactant administration (T0), 24 hours after the last dose of surfactant (T1), and 24 hours after ECMO decannulation (T2)...
May 11, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/29754028/frequency-and-factors-associated-with-providing-injection-initiation-assistance-in-tallinn-estonia
#8
Anneli Uusküla, David M Barnes, Mait Raag, Ave Talu, Susan Tross, Don C Des Jarlais
Injection drug use is expanding in numerous regions in the world. Persons who inject drugs (PWID) play an important role encouraging new persons into injecting, by providing injection initiation assistance ("assisting" behaviors) and stimulating interest in injection ("promoting" behaviors). OBJECTIVES: To describe the prevalence of assisting and promoting behaviors, and to identify factors associated with assisting, among PWID in Tallinn, Estonia. METHODS: In 2016, PWID were recruited through respondent-driven sampling (RDS), interviewed, and HIV tested...
May 8, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29753344/challenges-in-research-and-health-technology-assessment-of-rare-disease-technologies-report-of-the-ispor-rare-disease-special-interest-group
#9
Sandra Nestler-Parr, Daria Korchagina, Mondher Toumi, Chris L Pashos, Christopher Blanchette, Elizabeth Molsen, Thomas Morel, Steven Simoens, Zoltán Kaló, Ruediger Gatermann, William Redekop
BACKGROUND: Successful development of new treatments for rare diseases (RDs) and their sustainable patient access require overcoming a series of challenges related to research and health technology assessment (HTA). These impediments, which may be unique to RDs or also apply to common diseases but are particularly pertinent in RDs, are diverse and interrelated. OBJECTIVE: To develop for the first time a catalog of primary impediments to RD research and HTA, and to describe the cause and effect of individual challenges...
May 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/29739452/-elective-caesarean-section-at-38-39-weeks-gestation-compared-to-39-weeks-on-neonatal-outcomes-a-prospective-cohort-study
#10
Reihaneh Pirjani, Motahareh Afrakhteh, Mahdi Sepidarkish, Shahin Nariman, Mahboobeh Shirazi, Ashraf Moini, Ladan Hosseini
BACKGROUND: This study was conducted to compare neonatal complications in scheduled cesarean sections (CS) between 38 and 39 gestational weeks with CS performed after 39 gestational weeks in Iranian low -risk pregnant women. METHODS: In this cohort study, 2086 patients were enrolled based on the inclusion and exclusion criteria. The neonates were evaluated in terms of the following items: transient tachypnea of the newborn (TTN), respiratory distress syndrome (RDS), sepsis, need for NICU hospitalization, birth weight, birth height, head circumference, and the first minute and fifth minute Apgar score...
May 8, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29732488/coronary-flow-reserve-in-systemic-rheumatic-diseases-a-systematic-review-and-meta-analysis
#11
REVIEW
Gian Luca Erre, Giorgio Buscetta, Panagiotis Paliogiannis, Arduino Aleksander Mangoni, Ciriaco Carru, Giuseppe Passiu, Angelo Zinellu
Coronary flow reserve (CFR), a measure of both obstructive coronary artery disease and microvascular dysfunction, has been evaluated in systemic rheumatic diseases (RDs), but a comprehensive critical appraisal of the available evidence is lacking. The objective of this study is to conduct a systematic review and meta-analysis of studies with small sample size investigating the associations between the presence of RDs and CFR to increase statistical power and accuracy. PubMed, Web of Science, Scopus, and Google Scholar, from inception to March 2018, were searched for studies reporting on CFR in RDs in comparison to healthy subjects...
May 7, 2018: Rheumatology International
https://www.readbyqxmd.com/read/29727629/losartan-prevents-the-imbalance-between-renal-dopaminergic-and-renin-angiotensin-systems-induced-by-fructose-overload-l-dopa-dopamine-index-as-new-potential-biomarker-of-renal-dysfunction
#12
Natalia Lucía Rukavina Mikusic, Nicolás Martín Kouyoumdzian, Ana Uceda, Julieta Sofía Del Mauro, Marcela Pandolfo, Mariela Mercedes Gironacci, Ana María Puyó, Jorge Eduardo Toblli, Belisario Enrique Fernández, Marcelo Roberto Choi
BACKGROUND: The renin angiotensin system (RAS) and the renal dopaminergic system (RDS) act as autocrine and paracrine systems to regulate renal sodium management and inflammation and their alterations have been associated to hypertension and renal damage. Nearly 30-50% of hypertensive patients have insulin resistance (IR), with a strong correlation between hyperinsulinemia and microalbuminuria. OBJECTIVE: The aim of this study was to demonstrate the existence of an imbalance between RAS and RDS associated to IR, hypertension and kidney damage induced by fructose overload (FO), as well as to establish their prevention, by pharmacological inhibition of RAS with losartan...
May 1, 2018: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/29725307/comparing-reentrant-drivers-predicted-by-image-based-computational-modeling-and-mapped-by-electrocardiographic-imaging-in-persistent-atrial-fibrillation
#13
Patrick M Boyle, Joe B Hakim, Sohail Zahid, William H Franceschi, Michael J Murphy, Edward J Vigmond, Rémi Dubois, Michel Haïssaguerre, Mélèze Hocini, Pierre Jaïs, Natalia A Trayanova, Hubert Cochet
Electrocardiographic mapping (ECGI) detects reentrant drivers (RDs) that perpetuate arrhythmia in persistent AF (PsAF). Patient-specific computational models derived from late gadolinium-enhanced magnetic resonance imaging (LGE-MRI) identify all latent sites in the fibrotic substrate that could potentially sustain RDs, not just those manifested during mapped AF. The objective of this study was to compare RDs from simulations and ECGI (RDsim /RDECGI ) and analyze implications for ablation. We considered 12 PsAF patients who underwent RDECGI ablation...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29721951/mapping-of-canine-models-of-inherited-retinal-diseases
#14
Keiko Miyadera
The gene/mutation discovery approaches for inherited retinal diseases (RDs) in the dog model have seen considerable development over the past 25 years. Initial attempts were focused on candidate genes, followed by genome-wide approaches including linkage analysis and DNA-chip-based genome-wide association study. Combined, there are as many as 32 mutations in 27 genes that have been associated with canine retinal diseases to date. More recently, next-generation sequencing has become one of the key methods of choice...
2018: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29719289/the-effect-of-minimally-invasive-surfactant-therapy-on-diaphragmatic-activity
#15
Cornelia G de Waal, Gerard J Hutten, Frans H de Jongh, Anton H van Kaam
BACKGROUND: Minimally invasive surfactant therapy (MIST) is increasingly used to treat preterm infants with respiratory distress syndrome (RDS). However, the effect of MIST on breathing effort is poorly studied. OBJECTIVES: To describe the effect of MIST on neural breathing effort assessed with transcutaneous electromyography of the diaphragm (dEMG) in preterm infants with RDS. METHODS: Preterm infants with a gestational age < 37 weeks treated with MIST for RDS were included...
May 2, 2018: Neonatology
https://www.readbyqxmd.com/read/29708084/age-bias-in-survey-sampling-and-implications-for-estimating-hiv-prevalence-in-men-who-have-sex-with-men-insights-from-mathematical-modelling
#16
L F Johnson, P Mulongeni, A Marr, T Lane
Respondent-driven sampling (RDS) is widely used to estimate HIV prevalence in men who have sex with men (MSM). Mathematical models that are calibrated to these data may be compromised if they fail to account for selection biases in RDS surveys. To quantify the potential extent of this bias, an agent-based model of HIV in South Africa was calibrated to HIV prevalence and sexual behaviour data from South African studies of MSM, first reweighting the modelled MSM population to match the younger age profile of the RDS surveys (age-adjusted analysis) and then without reweighting (unadjusted analysis)...
April 30, 2018: Epidemiology and Infection
https://www.readbyqxmd.com/read/29705827/religious-discrimination-scale-development-and-initial-psychometric-evaluation
#17
G E Kawika Allen, Kenneth T Wang, P Scott Richards, Mason Ming, Han Na Suh
This study presents the development and initial psychometric evaluation of the Religious Discrimination Scale (RDS). This 11-item instrument identified three dimensions based on perceived discrimination experiences of members of The Church of Jesus Christ of Latter-day Saints (LDS): Perceived Prejudice, Closet Symptoms, and Negative Labels. The psychometric evaluations of the RDS indicated a strong and clear factor structure as well as good internal consistency reliability. The test of measurement and structural invariance across gender also suggested that the RDS scale is equally appropriate to be used with both men and women...
April 28, 2018: Journal of Religion and Health
https://www.readbyqxmd.com/read/29703180/dental-age-estimation-in-southern-chinese-population-using-panoramic-radiographs-validation-of-three-population-specific-reference-datasets
#18
Jayakumar Jayaraman, Graham J Roberts, Hai Ming Wong, Nigel M King
BACKGROUND: The accuracy of estimated age should depend on the reference data sets (RDS) from which the maturity scores or Ages of Attainment (AoA) were obtained. This study aimed to test the accuracy of age estimation from three different population specific dental reference datasets (RDS). METHODS: Two hundred and sixty six dental panoramic radiographs of subjects belonging to southern Chinese ethnicity were scored and dental age (DA) was estimated from three reference datasets: French-Canadian, United Kingdom (UK) Caucasian and southern Chinese...
April 27, 2018: BMC Medical Imaging
https://www.readbyqxmd.com/read/29702992/gender-related-efficacy-of-pulmonary-surfactant-in-infants-with-respiratory-distress-syndrome-a-strobe-compliant-study
#19
Chen Chen, Tian Tian, Li Liu, Juan Zhang, Huiling Fu
Whether gender influences the efficacy of exogenous pulmonary surfactant (PS) for replacement therapy in newborns with respiratory distress syndrome (RDS) has not been well studied yet.Retrospective cohort study design. Data on PS therapy including blood gas, oxygenation function parameters, and therapy results were collected and analyzed from 370 infants diagnosed with RDS in 20 hospitals of the Northwest China Neonatal Collaboration from January 2011 to December 2011.Female infants were more sensitive to PS treatment than males...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29694989/is-less-invasive-surfactant-administration-necessary-or-only-helpful-or-just-a-fashion
#20
Gianluca Lista, Ilia Bresesti, Laura Fabbri
In the 1990s, the most relevant pillars in the treatment of neonatal respiratory distress syndrome (RDS) have been improvements in ventilation strategies, the introduction of exogenous surfactant replacement therapy, and the use of antenatal steroids. Lately, in addition to the standard INSURE (INtubation-SURfactant administration-Extubation) method to administer surfactant, a new technique has been gaining increasing popularity. It is the so-called less invasive surfactant administration (LISA) method, which has shown promising results in preventing bronchopulmonary dysplasia development and in reducing mortality in preterm neonates...
May 2018: American Journal of Perinatology
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