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https://www.readbyqxmd.com/read/28734149/discharge-management-strategies-and-post-discharge-care-interventions-for-depression-systematic%C3%A2-review-and-meta-analysis
#1
REVIEW
F Holzinger, S Fahrenkrog, S Roll, F Kleefeld, M Adli, C Heintze
BACKGROUND: Patients with depression require treatment continuity when discharged from inpatient care. Interventions aimed at optimizing transition into outpatient care may be effective in preventing symptom deterioration and readmission. We aimed to evaluate the effectiveness of care transition interventions for patients with depression after psychiatric hospitalization. METHODS: Systematic review and random-effects meta-analysis of controlled trials. Primary outcomes were readmissions and symptoms of depression...
July 11, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28732241/generation-of-skeletal-myogenic-progenitors-from-human-pluripotent-stem-cells-using-non-viral-delivery-of-minicircle-dna
#2
Jaemin Kim, Vanessa K P Oliveira, Ami Yamamoto, Rita C R Perlingeiro
Currently, the most efficient and promising approach for generating large numbers of engraftable human skeletal myogenic progenitors from pluripotent stem cells requires the conditional in vitro overexpression of PAX7 using lentiviral vectors. Because a non-integrating approach would be preferable to eliminate or minimize the risk associated with random genomic integration, here we investigate whether transient expression of PAX7 using minicircle DNA would enable the generation of functional pluripotent stem cell-derived myogenic progenitors, equivalent to those generated by lentivirus...
July 12, 2017: Stem Cell Research
https://www.readbyqxmd.com/read/28732018/carboplatin-with-intravenous-and-subsequent-oral-administration-of-vinorelbine-in-resected-non-small-cell-lung-cancer-in-real-world-set-up
#3
Vítězslav Kolek, Ivona Grygárková, Leona Koubková, Jana Skřičková, Jiřina Švecová, Dimka Sixtová, Jiří Bartoš, Aleš Tichopád
OBJECTIVES: Adjuvant cisplatin-based chemotherapy is recommended for routine use in patients with Stage IIA, IIB or IIIA non-small cell lung cancer (NSCLC) after complete resection. Results obtained for Stage IB were not conclusive. While vinorelbine plus cisplatin is the preferred choice after resection, combining vinorelbine with carboplatin promises improved compliance and delivery of drugs due to lower toxicity. We evaluated the impact of this option on treatment compliance and survival under real-world conditions...
2017: PloS One
https://www.readbyqxmd.com/read/28731569/diversity-in-thermal-affinity-among-key-piscivores-buffers-impacts-of-ocean-warming-on-predator-prey-interactions
#4
Rebecca L Selden, Ryan D Batt, Vincent S Saba, Malin L Pinsky
Asymmetries in responses to climate change have the potential to alter important predator-prey interactions, in part by altering the location and size of spatial refugia for prey. We evaluated the effect of ocean warming on interactions between four important piscivores and four of their prey in the U.S. Northeast Shelf by examining species overlap under historical conditions (1968-2014) and with a doubling in CO2 . Because both predator and prey shift their distributions in response to changing ocean conditions, the net impact of warming or cooling on predator-prey interactions was not determined a priori from the range extent of either predator or prey alone...
July 21, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28731532/formate-and-nitrate-utilization-in-enterobacter-aerogenes-for-semi-anaerobic-production-of-isobutanol
#5
Hwi-Min Jung, Yong Hwan Kim, Min-Kyu Oh
Anaerobic bioprocessing is preferred because of its economic advantages. However, low productivity and decreased growth of the host strain have limited the use of the anaerobic process. Anaerobic respiration can be applied to anoxic processing using formate and nitrate metabolism to improve the productivity of value-added metabolites. We constructed isobutanol-producing strains using Enterobacter aerogenes as a host strain by metabolic engineering approaches. The byproduct pathway (ldhA, budA, and pflB) was knocked out, and heterologous keto-acid decarboxylase (kivD) and alcohol dehydrogenase (adhA) were expressed along with the L-valine synthesis pathway (ilvCD and budB)...
July 21, 2017: Biotechnology Journal
https://www.readbyqxmd.com/read/28730748/extracellular-signal-regulated-kinase-activation-in-the-spinal-cord-contributes-to-visceral-hypersensitivity-induced-by-craniofacial-injury-followed-by-stress
#6
Y-J Zhao, J-H Li, B Hu, Y Wang, X-F Chang, R J Traub, D-Y Cao
BACKGROUND: We previously developed an animal model to examine mechanisms that underlie the emergence of visceral hypersensitivity modeling pain characteristics of temporomandibular disorder (TMD) patients with comorbid irritable bowel syndrome (IBS). In ovariectomized (OVx) rats with estradiol (E2) replacement, visceral hypersensitivity developed subsequent to masseter muscle inflammation followed by repeated forced swim (FS) stress. The purpose of this study was to investigate whether activation of extracellular signal-regulated kinase (ERK) in the spinal cord contributes to visceral hypersensitivity in this overlapping pain model...
July 21, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/28729902/high-tolerance-to-high-light-conditions-for-the-protected-species-ariocarpus-kotschoubeyanus-cactaceae
#7
Erika Arroyo-Pérez, Joel Flores, Claudia González-Salvatierra, María L Matías-Palafox, Cecilia Jiménez-Sierra
We determined the seasonal ecophysiological performance under perennial plants and under high solar radiation for adult individuals from the 'living rock' cactus Ariocarpus kotschoubeyanus, which occurs equally under nurse plants and in open spaces. We evaluated the effective quantum yield of photosystem II (ΦPSII) and the dissipation of thermal energy [non-photochemical quenching (NPQ)] thorough the year. The maximum apparent electron transport rate (ETRmax) and the saturating photosynthetically active photon flux density for PSII (PFDsat) were also determined from rapid light curves...
2017: Conservation Physiology
https://www.readbyqxmd.com/read/28729304/effectiveness-of-the-management-of-major-depressive-episodes-disorder-in-adults-with-comorbid-chronic-physical-diseases-a-protocol-for-a-systematic-review-and-meta-analysis
#8
Pablo Martínez, Ariel Castro, Diego Alonso, Paul A Vöhringer, Graciela Rojas
INTRODUCTION: Depression is a global-scale public health problem, and a significant association has been established between depression and chronic physical diseases. This growing comorbidity poses a challenge to healthcare systems. We aim to assess the effectiveness of the management of major depressive episodes/disorder in adults with comorbid chronic physical diseases. METHODS AND ANALYSIS: We will conduct a systematic review and meta-analysis of randomised clinical trials...
July 20, 2017: BMJ Open
https://www.readbyqxmd.com/read/28729221/sensitivity-to-cocaine-in-adult-mice-is-due-to-interplay-between-genetic-makeup-early-environment-and-later-experience
#9
Matteo Di Segni, Diego Andolina, Alessandra Coassin, Alessandra Accoto, Alessandra Luchetti, Tiziana Pascucci, Carla Luzi, Anna Rita Lizzi, Francesca R D'Amato, Rossella Ventura
Although early aversive postnatal events are known to increase the risk to develop psychiatric disorders later in life, rarely they determine alone the nature and outcome of the psychopathology, indicating that interaction with genetic factors is crucial for expression of psychopathologies in adulthood. Moreover, it has been suggested that early life experiences could have negative consequences or confer adaptive value in different individuals. Here we suggest that resilience or vulnerability to adult cocaine sensitivity depends on a "triple interaction" between genetic makeup x early environment x later experience...
July 17, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/28728776/collaborating-with-parents-of-children-with-chronic-conditions-and-professionals-to-design-develop-and-pre-pilot-plant-the-parent-learning-needs-and-preferences-assessment-tool
#10
Ruth Nightingale, Lucy Wirz, Wendy Cook, Veronica Swallow
PURPOSE: This study aimed to design, develop and pre-pilot an assessment tool (PLAnT) to identify parents' learning needs and preferences when carrying out home-based clinical care for their child with a chronic condition. DESIGN AND METHODS: A mixed methods, two-phased design was used. Phase 1: a total of 10 parents/carers and 13 professionals from six UK's children's kidney units participated in qualitative interviews. Interview data were used to develop the PLAnT...
July 2017: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/28727930/visual-perception-of-british-women-s-skin-color-distribution-in-two-nonindustrialized-societies-the-maasai-and-the-tsimane
#11
Bernhard Fink, Marina Butovskaya, Piotr Sorokowski, Agnieszka Sorokowska, Paul J Matts
In women with lightly pigmented skin in particular, facial skin color homogeneity decreases with age, primarily due to chronic exposure to solar ultraviolet radiation (UVR), leading to a decrease in perceived health and attractiveness. Perception of female skin may be influenced by continuous exposure to, and thus familiarity with, age-related changes in visible skin condition in a given society. Men and women of two traditional societies, the Maasai (Tanzania) and the Tsimane' (Bolivia), unfamiliar with lighter colored skin, judged images of British women's facial skin for age, health, and attractiveness...
July 2017: Evolutionary Psychology: An International Journal of Evolutionary Approaches to Psychology and Behavior
https://www.readbyqxmd.com/read/28727475/guidance-for-supplemental-enteral-nutrition-across-patient-populations
#12
Douglas L Nguyen
Enteral nutrition is preferred over parenteral nutrition as a result of the greater safety of enteral nutrition therapy and comparative convenience. A wide variety of enteral nutrition products have been developed, including disease-specific products to help manage the nutritional needs of patients with kidney failure, liver failure, lung disease, diabetes, and other conditions. An assessment of each patient's nutritional needs and digestive function should be conducted prior to initiation of enteral nutrition therapy...
July 2017: American Journal of Managed Care
https://www.readbyqxmd.com/read/28727386/retroperitoneal-access-for-robotic-renal-surgery
#13
Barrett G Anderson, Alec J Wright, Aaron M Potretzke, R Sherburne Figenshau
INTRODUCTION AND OBJECTIVE: Retroperitoneal access for robotic renal surgery is an effective alternative to the commonly used transperitoneal approach. We describe our contemporary experience and technique for attaining retroperitoneal access. MATERIALS AND METHODS: We outline our institutional approach to retroperitoneal access for the instruction of urologists at the beginning of the learning curve. The patient is placed in the lateral decubitus position. The first incision is made just inferior to the tip of the twelfth rib as described by Hsu, et al...
July 20, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28727263/hearing-outcomes-of-incus-interposition-versus-titanium-partial-ossicular-replacement-prostheses-our-experience-in-115-patients
#14
Elisabeth Sterrer, Benjamin Loader
Both, PORP and incus interpositions, are valuable techniques for the reconstruction of the conductive mechanism. In our study we were able to show that, in certain aspects, the audiological outcome was better in incus remodelling reconstruction than in PORP placement. A detailed analysis of all frequencies showed significantly better results in the incus group especially for the frequencies 250Hz, 1000Hz, 2000Hz and 3000Hz. If clinical conditions warrant it, a reconstruction of the ossicular chain with incus interposition may be preferred to PORP...
July 20, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28726953/4-4-di-tert-butyl-6-1h-tetrazol-5-yl-2-2-bipyridine-modification-of-a-highly-selective-n-donor-ligand-for-the-separation-of-trivalent-actinides-from-lanthanides
#15
Martin M Maiwald, Anna T Wagner, Jochen Kratsch, Andrej Skerencak-Frech, Michael Trumm, Andreas Geist, Peter W Roesky, Petra J Panak
In the present work, the complexation and extraction behaviour of 4,4'di-tert-butyl-6-(1H-tetrazol-5-yl)-2,2'-bipyridine (HN4(t)bubipy) towards trivalent actinides (An(iii)) and lanthanides (Ln(iii)) is studied by spectroscopic methods, liquid-liquid extraction, and quantum chemical calculations. The ligand synthesis of HN4(t)bubipy as well as its application in coordination chemistry of the 4f elements is described. Reaction of HN4(t)bubipy with [Ln(NO3)3·6H2O] (Ln = Sm, Eu) results in [H2N4(t)bubipy](+)[Ln(N4(t)bubipy)(NO3)3(H2O)](-)...
July 20, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28726800/role-of-nicotinamide-n-methyltransferase-in-dorsal-striatum-in-cocaine-place-preference
#16
Li Luo, Fei-Fei Shang, Hailei Long, Linhong Jiang, Ruiming Zhu, Qian Zhao, Hui Gu, Jueying Kong, Wei Xu, Yinglan Zhao, Xiaobo Cen
Nicotinamide N-methyltransferase (NNMT) transfers the methyl from S-adenosyl-L-methionine (SAM) to nicotinamide (NA) to produce S-adenosyl-L-homocysteine (SAH) and 1-methylnicotinamide (MeN). NNMT has been implicated in a variety of diseases; however, the role of NNMT in drug addiction is largely unknown. Here, we found that the expression of Nnmt was significantly upregulated in the dorsal striatum (DS) of cocaine-conditioned mice. Cocaine significantly decreased SAM/SAH ratio levels in the DS, which was accompanied with the decreased activities of Rac1 and RhoA...
July 20, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28726734/ranging-behaviour-of-commercial-free-range-broiler-chickens-1-factors-related-to-flock-variability
#17
Peta S Taylor, Paul H Hemsworth, Peter J Groves, Sabine G Gebhardt-Henrich, Jean-Loup Rault
Little is known about the ranging behaviour of chickens. Understanding ranging behaviour is required to improve management and shed and range design to ensure optimal ranging opportunities. Using Radio Frequency Identification technology, we tracked 300 individual broiler chickens in each of four mixed sex ROSS 308 flocks on one commercial farm across two seasons. Ranging behaviour was tracked from the first day of range access (21 days of age) until 35 days of age in winter and 44 days of age in summer. Range use was higher than previously reported from scan sampling studies...
July 20, 2017: Animals: An Open Access Journal From MDPI
https://www.readbyqxmd.com/read/28725941/endoscopic-stents-for-the-biliary-tree-and-pancreas
#18
REVIEW
Rajesh Krishnamoorthi, Mahendran Jayaraj, Richard Kozarek
OPINION STATEMENT: PURPOSE OF REVIEW: To review the recently published literature on biliary and pancreatic stents. RECENT FINDINGS: Covered self-expanding metal stents (SEMS) are increasingly being used in the endoscopic management of benign biliary strictures. Given the costs associated with SEMS, plastic stents are still the most commonly used stents. In this setting, SEMS are preferred over plastic stents for palliation of malignant biliary strictures due to superior patency and have a role in preoperative management of malignant biliary strictures...
July 20, 2017: Current Treatment Options in Gastroenterology
https://www.readbyqxmd.com/read/28725484/logarithmic-sensing-in-bacillus-subtilis-aerotaxis
#19
Filippo Menolascina, Roberto Rusconi, Vicente I Fernandez, Steven Smriga, Zahra Aminzare, Eduardo D Sontag, Roman Stocker
Aerotaxis, the directed migration along oxygen gradients, allows many microorganisms to locate favorable oxygen concentrations. Despite oxygen's fundamental role for life, even key aspects of aerotaxis remain poorly understood. In Bacillus subtilis, for example, there is conflicting evidence of whether migration occurs to the maximal oxygen concentration available or to an optimal intermediate one, and how aerotaxis can be maintained over a broad range of conditions. Using precisely controlled oxygen gradients in a microfluidic device, spanning the full spectrum of conditions from quasi-anoxic to oxic (60 n mol/l-1 m mol/l), we resolved B...
2017: NPJ Systems Biology and Applications
https://www.readbyqxmd.com/read/28725411/choosing-a-mate-in-a-high-predation-environment-female-preference-in-the-fiddler-crab-uca-terpsichores
#20
Daniela M Perez, John H Christy, Patricia R Y Backwell
The interplay between a receiver's sensory system and a sender's courtship signals is fundamental to the operation of sexual selection. Male courtship signals that match a female receiver's preexisting perceptual biases can be favored yet the message they communicate is not always clear. Do they simply beacon the male's location or also indicate his quality? We explored this question in a species of fiddler crab Uca terpsichores that courts under elevated predation risk and that mates and breeds underground in the safety of males' burrows...
October 2016: Ecology and Evolution
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