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https://www.readbyqxmd.com/read/26564456/-roles-of-tumor-infiltrating-lymphocytes-in-non-small-cell-lung-cancer-recurrence-and-metastasis-a-meta-analysis
#1
Xiang Yan, Shun-chang Jiao
OBJECTIVE: To determine the prognostic value of tumor-infiltrating lymphocytes in the recurrence and metastasis of non-small cell lung cancer (NSCLC). METHODS: A PubMed, EMBASE, Cochrane Library databases, NIH databases, and China Biology Medicine disc, China National Knowledge Infrastructure, Chinese Science and Technology Periodical literature search strategy was designed. Studies on the prognostic values of intratumoural CD3⁺,CD4⁺,CD8⁺, and FoxP3+lymphocytes for NSLCL were retrieved...
August 2015: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/26379973/cytotoxic-t-lymphocyte-associated-antigen-4-49a-g-polymorphism-and-the-risk-of-non-small-cell-lung-cancer-in-a-chinese-population
#2
Hui-Ning Liu, Jian-Ling Su, Shao-Hui Zhou, Li-Jun Liu, Peng Qie
BACKGROUND: CTLA-4 is a potent immunoregulatory molecule and plays a pivotal role in the negative regulation of T-cell proliferation and activation. Previously, the association between CTLA-4 +49A>G polymorphism and the risk of NSCLC has been investigated in several studies, however, their results were inconsistent. Therefore, we aimed to investigated the association between CTLA-4 +49A>G polymorphism and the risk of NSCLC in a Chinese population. METHODS: We recruited 231 NSCLC patients and 250 healthy controls in the present case-control study...
2015: International Journal of Clinical and Experimental Medicine
https://www.readbyqxmd.com/read/25481662/how-do-elderly-poor-prognosis-patients-tolerate-palliative-concurrent-chemoradiotherapy-for-locally-advanced-non-small-cell-lung-cancer-stage-iii-a-subset-analysis-from-a-clinical-phase-iii-trial
#3
MULTICENTER STUDY
Hans H Strøm, Roy M Bremnes, Stein H Sundstrøm, Nina Helbekkmo, Ulf Aasebø
BACKGROUND: In a phase III trial of patients with unresectable, locally advanced, stage III non-small-cell lung cancer (NSCLC) with a poor prognosis, palliative concurrent chemoradiotherapy (CRT) provided a significantly better outcome than chemotherapy alone, except among performance status (PS) 2 patients. In the present subgroup analysis, we evaluated the effect on patients aged ≥ 70 years (42% of all included) compared with patients aged < 70 years enrolled in the trial. PATIENTS AND METHODS: All patients received 4 courses of intravenous carboplatin and oral vinorelbine...
May 2015: Clinical Lung Cancer
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