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Norachart Sirisreetreerux, Babar Shafiq, Greg M Osgood, Erik A Hasenboehler
OBJECTIVES: To determine the location of distal medial neurovascular structures, identifying a medial "safe zone" for minimally invasive plate osteosynthesis to treat displaced femoral condylar fractures. METHODS: Eleven uninjured lower-half torsos were dissected on the bilateral medial lower thigh. A longitudinal incision was made at the midsagittal plane of the medial thigh starting 1 cm proximal to the knee joint and extending to the proximal one-third of the femur...
November 2016: Journal of Orthopaedic Trauma
Jean-Rene Arseneau, Royce Steeves, Mark Laflamme
The increasing use of high-throughput sequencing platforms has made the isolation of pure, high molecular weight DNA a primary concern for studies of a diverse range of organisms. Purification of DNA remains a significant challenge in many tissue and sample types due to various organic and inorganic molecules that co-precipitate with nucleic acids. Molluscs, for example, contain high concentrations of polysaccharides which often co-precipitate with DNA and can inhibit downstream enzymatic reactions. We modified a low-salt CTAB (MoLSC) extraction protocol to accommodate contaminant rich animal tissues and compared this method to a standard CTAB extraction protocol and two commercially available animal tissue DNA extraction kits using oyster adductor muscle...
October 21, 2016: Molecular Ecology Resources
Luca La Colla, Jacques E Chelly
No abstract text is available yet for this article.
November 2016: Anesthesiology
Bhupinder Singh, Huy Vo, Shelby L Francis, Kathleen F Janz, John H Yack
PURPOSE: This study assessed the biomechanical gait changes in obese and normal weight female adult subjects following a commonly recommended 30-minute walking session. Hip and knee adduction and extensor moments, which are the primary modulators of frontal and sagittal plane load distribution were hypothesized to increase in obese females following a 30-minute walking period, resulting in more stress across the hip and knee joint. METHODS: Ten obese (37.7 ± 4...
October 6, 2016: Medicine and Science in Sports and Exercise
Y M Zheng, W Z Li, Z X Wang, W Zhang, H Lv, J X Xiao, Y Yuan
OBJECTIVE: To report thigh muscle magnetic resonance imaging (MRI) tests of four Chinese patients with dystrophinopathy with edema changes in adductor longus muscles that mimics adductor enthesopathy. METHODS: Four boys, who were from four unrelated families and aged from 5 to 11 years, were investigated because of the clinical manifestations including myalgia or muscle weakness or the incidental findings of elevated serum creatine kinase levels, and were diagnosed with dystrophinopathy by gene test of Duchenne muscular dystrophy (DMD)...
October 18, 2016: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
Brian M Ilfeld
A continuous peripheral nerve block (CPNB) consists of a percutaneously inserted catheter with its tip adjacent to a target nerve/plexus through which local anesthetic may be administered, providing a prolonged block that may be titrated to the desired effect. In the decades after its first report in 1946, a plethora of data relating to CPNB was published, much of which was examined in a 2011 Anesthesia & Analgesia article. The current update is an evidence-based review of the CPNB literature published in the interim...
October 3, 2016: Anesthesia and Analgesia
Paul M Heerdt, Hiroshi Sunaga, Joel S Owen, Matthew T Murrell, Jaideep K Malhotra, Deena Godfrey, Michelle Steinkamp, Peter Savard, John J Savarese, Cynthia A Lien
BACKGROUND: CW002 is a benzylisoquinolinium nondepolarizing neuromuscular-blocking drug found to be inactivated by cysteine in preclinical studies. The current study represents a dose escalation clinical trial designed to describe CW002 potency, duration, cardiopulmonary side effects, and histamine release. METHODS: Healthy subjects anesthetized with sevoflurane/nitrous oxide were divided into five groups (n = 6), each receiving a fixed CW002 dose (0.02, 0.04, 0...
October 6, 2016: Anesthesiology
Aparna Shukla, Shilpi Misra
CONTEXT: Clinical need for a nondepolarizing agent with a rapid onset time and a brief duration of action has led to the development of rocuronium bromide. AIMS: The aim of this study was to evaluate optimal dose of rocuronium bromide for intubation and to compare the onset time, duration of action, intubating conditions, and hemodynamic effects of two doses of rocuronium bromide. SETTINGS AND DESIGN: A prospective, randomized, double-blind study...
September 2016: Anesthesia, Essays and Researches
Asanori Kiyuna, Norimoto Kise, Munehisa Hiratsuka, Shunsuke Kondo, Takayuki Uehara, Hiroyuki Maeda, Akira Ganaha, Mikio Suzuki
OBJECTIVES: Spasmodic dysphonia (SD) is considered a focal dystonia. However, the detailed pathophysiology of SD remains unclear, despite the detection of abnormal activity in several brain regions. The aim of this study was to clarify the pathophysiological background of SD. STUDY DESIGN: This is a case-control study. METHODS: Both task-related brain activity measured by functional magnetic resonance imaging by reading the five-digit numbers and resting-state functional connectivity (FC) measured by 150 T2-weighted echo planar images acquired without any task were investigated in 12 patients with adductor SD and in 16 healthy controls...
October 13, 2016: Journal of Voice: Official Journal of the Voice Foundation
Ross A Bogey, Lee A Barnes
The force of a single muscle is not directly measurable without invasive methods. Yet invasive techniques are not appropriate for clinical use, thus a non-invasive technique that combined the electromyographic (EMG) signal and a neuromuscular model was developed to determine in vivo active muscle forces at the hip. The EMG-to-force processing (EFP) model included active and passive moment components, and the net EFP moment was compared with the hip moment obtained with standard inverse dynamics techniques ("gold standard")...
October 12, 2016: IEEE Transactions on Neural Systems and Rehabilitation Engineering
H K Patterson, R H Carmichael
RATIONALE: Extraction of lipids from tissues prior to carbon stable isotope analysis (SIA) has become a common practice, despite a lack of species-specific data to indicate when lipid extraction is needed. Marine invertebrates, including bivalves, are known to store carbon as glycogen and less in the form of lipids than other species, potentially reducing the need for lipid extraction even when C:N values are above 3.5, a value that previous studies suggest indicates a need for lipid extraction of animal tissues...
October 5, 2016: Rapid Communications in Mass Spectrometry: RCM
Yasuhiro Morimoto, Tatsunori Haruoka
No abstract text is available yet for this article.
October 1, 2016: Acta Anaesthesiologica Taiwanica: Official Journal of the Taiwan Society of Anesthesiologists
Flavia Feijó Nunes, Lílian Bassani, Sabrina Alves Fernandes, Maria Eugênia Deutrich, Bianca Coccaro Pivatto, Cláudio Augusto Marroni
Background: Patients with liver disease often present protein-energy malnutrition. The assessment of food intake is very important in the investigation regarding the "health-disease" process. Objective: To assess dietary intake of cirrhotic patients through food record during 3 days, correlating it with the nutritional status of the patient and the stage of the disease. Methods: Cirrhotic outpatients from the Santa Casa de Misericórdia Hospital, RS, Brazil, were assessed...
October 2016: Arquivos de Gastroenterologia
Jeong Ho Kim, Yoon Chan Lee, Soo Il Lee, Sang Yoong Park, So Ron Choi, Jong Hwan Lee, Chan Jong Chung, Seung Cheol Lee
BACKGROUND: There are few information about the differences of the effective dose (ED) of cisatracurium between the adult and the elderly. We investigated the ED and the onset time of cisatracurium in the adults and the elderly. METHODS: We studied two hundred patients of the adults aged 20 through 64 years and the elderly aged ≥ 65 years, with American Society of Anesthesiologists physical status I or II. Each 100 patients with 20 patients of each dose group, randomly selected from 30, 40, 50, 60 or 70 µg/kg of cisatracurium, were randomly allocated to the adults and the elderly groups...
October 2016: Korean Journal of Anesthesiology
Suzi Edwards, Hiram C Brooke, Jill L Cook
OBJECTIVES: This study aimed to explore the differences in the magnitude of movement variability and strategies utilized during an unanticipated cut task between players with and without a history of groin pain. DESIGN: Cross-sectional design. SETTING: Biomechanics laboratory. PARTICIANTS: Male Australian football players with (HISTORY; n = 7) or without (CONTROL; n = 10) a history of groin pain. OUTCOME MEASURES: Three-dimensional ground reaction forces (GRF) and kinematics were recorded during 10 successful trials of an unanticipated cut task, and isokinetic hip adduction and abduction strength...
July 22, 2016: Physical Therapy in Sport
Thomas M Gooding, Mark A Feger, Joseph M Hart, Jay Hertel
CONTEXT:  The intrinsic foot muscles maintain the medial longitudinal arch and aid in force distribution and postural control during gait. Impaired intrinsic foot-muscle function has been linked to various foot conditions. Several rehabilitative exercises have been proposed to improve it; however, literature that identifies which individual muscles are activated during specific intrinsic foot-muscle exercises is lacking. OBJECTIVE:  To describe changes in activation of the intrinsic plantar foot muscles after 4 exercises as measured with T2 time magnetic resonance imaging (MRI)...
October 3, 2016: Journal of Athletic Training
M W Zhao, H Tian, N Wang, M Li, X Geng, Q Y Zhou
Objective: To assess the pain control efficiency of continuous adductor canal block in total knee arthroplasty. Methods: From October to December 2015, patients with severe knee osteoarthritis undergoing primary unilateral TKA were observed clinically.All of the patients received ultrasound-guided continuous adductor canal block after surgery.NPRS Pain score in rest and activity at 2, 6, 12, 24, 48 h after surgery were collected, preoperative and postoperative quadriceps strength at 24, 48 h were analyzed. Opioids consumption and anesthesia related adverse effects were also recorded...
September 20, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Karima Belhaj, Soumia Meftah, Siham Zahi, Fatima Lmidmani, Abdellatif Elfatimi
OBJECTIVE: Isokinetic evaluation allows accurate and reproducible measurement of dynamic muscle strength. It has several application areas, especially in sports, it allows the evaluation, rehabilitation and re-entrainment. It is rarely used for the hip joint. The objective of this study was to report the isokinetic profile of the abductor and adductor muscles of the hip in Moroccan professional players, while comparing players with a history of groin for those without medical history at the hip...
September 2016: Annals of Physical and Rehabilitation Medicine
George Macrinici, Michelle Drescher, James Ascan, Krzysztof Babicz, Janet Clark, Paul Lagomarcino
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
Anna Pichiecchio, Marta Rossi, Claudia Cinnante, Stefania Giovanna Colafati, Roberto De Icco, Rossella Parini, Francesca Menni, Francesca Furlan, Alberto Burlina, Michele Sacchini, Maria Alice Donati, Simona Fecarotta, Roberto Della Casa, Federica Deodato, Roberta Taurisano, Maja Di Rocco
INTRODUCTION: The aim of this study was to evaluate the muscle MRI pattern of 9 patients (median age: 6.5±2.74 years) affected by classic infantile-onset Pompe disease (IOPD) who were treated with enzyme replacement therapy (ERT). METHODS: We performed and qualitatively scored T1-weighted (T1-w) sequences of the facial, shoulder girdle, paravertebral, and lower limb muscles and short-tau inversion recovery (STIR) sequences of the lower limbs using the Mercuri and Morrow scales, respectively...
September 26, 2016: Muscle & Nerve
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