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https://www.readbyqxmd.com/read/29679839/xenon-detection-in-human-blood-analytical-validation-by-accuracy-profile-and-identification-of-critical-storage-parameters
#1
Cécile Frampas, Julia Ney, Mark Coburn, Marc Augsburger, Vincent Varlet
Xenon is a rare, mostly inert, noble gas that has applications in a wide range of fields, including medicine. Xenon acts on the human body as a useful organ-protective and anesthetic agent and has also been previously studied for potential applications in fields such as optics, aerospace and medical imaging. Recently, it was discovered that xenon can boost erythropoietin production, and it has been used as a performance-enhancing agent in international sports competitions such as the Sochi Olympic Games. Therefore, screening methods to detect the misuse of xenon by analysis of biological samples and to monitor anesthesia kinetics and efficiency are being investigated...
April 13, 2018: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/29679411/the-use-of-a-logistic-regression-model-to-develop-a-risk-assessment-of-intraoperatively-acquired-pressure-ulcer
#2
Ling Gao, Lina Yang, Xiaoqin Li, Jin Chen, Juan Du, Xiaoxia Bai, Xianjun Yang
AIMS AND OBJECTIVES: To screen the factors of intraoperatively acquired pressure ulcer (IAPU) and establish a new risk assessment model of IAPU. DESIGN: This is a prospective study. METHODS: A total of 1963 patients who received neurosurgery, orthopaedics, pediatric surgery and cardiac surgery therapy in Sichuan Academy of Medical Science and Provincial People's Hospital in China from October 2015 to October 2016 were enrolled in the study and their clinical parameters were collected...
April 20, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29678977/minimizing-icu-neurological-dysfunction-with-dexmedetomidine-induced-sleep-mindds-protocol-for-a-randomised-double-blind-parallel-arm-placebo-controlled-trial
#3
Kenneth T Shelton, Jason Qu, Federico Bilotta, Emery N Brown, Gaston Cudemus, David A D'Alessandro, Hao Deng, Alan DiBiasio, Jacob A Gitlin, Eunice Y Hahm, Lauren E Hobbs, Timothy T Houle, Reine Ibala, Marco Loggia, Kara J Pavone, Shahzad Shaefi, George Tolis, M Brandon Westover, Oluwaseun Akeju
INTRODUCTION: Delirium, which is prevalent in postcardiac surgical patients, is an acute brain dysfunction characterised by disturbances in attention, awareness and cognition not explained by a pre-existing neurocognitive disorder. The pathophysiology of delirium remains poorly understood. However, basic science and clinical studies suggest that sleep disturbance may be a modifiable risk factor for the development of delirium. Dexmedetomidine is a α-2A adrenergic receptor agonist medication that patterns the activity of various arousal nuclei similar to sleep...
April 20, 2018: BMJ Open
https://www.readbyqxmd.com/read/29678137/supporting-teams-to-optimize-function-and-independence-in-veterans-a-multi-study-program-and-mixed-methods-protocol
#4
Virginia Wang, Kelli Allen, Courtney H Van Houtven, Cynthia Coffman, Nina Sperber, Elizabeth P Mahanna, Cathleen Colón-Emeric, Helen Hoenig, George L Jackson, Teresa M Damush, Erika Price, Susan N Hastings
BACKGROUND: Successful implementation of new clinical programs depends on effectively establishing, reorganizing, or enhancing team structures and processes to coordinate the work of individuals who are interdependent in their tasks, manage relationships, and share responsibility for outcomes. However, a one-size-fits-all approach is rarely effective. In partnership with VA national clinical leaders and local clinical champions, the Optimizing Function and Independence VA Quality Enhancement Research Initiative program (Function QUERI) will evaluate efforts to implement team-based clinical programs for Veterans at risk for functional decline and disability...
April 20, 2018: Implementation Science: IS
https://www.readbyqxmd.com/read/29677997/the-perspective-of-nurses-on-nursing-information-system-a-case-study-in-a-developing-country
#5
Masoumeh Sarbaz, Khalil Kimiafar, Elham Nazari
The purpose of this study was to investigate the effect of nursing information system (NIS) on clinical performance from the perspective of nurses in an academic hospital affiliated to Mashhad University of Medical Sciences in Iran. This descriptive cross-sectional study was conducted in 2016. We collected data targeting nurses with over three years' experience in using the NIS (120 nurses). NIS had caused improvement in "accuracy the consistency of drug, lab tests and radiology requests", "increasing the speed of the automated extracting of minimum data set for decision making and care trends" with the means of 4...
2018: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/29677972/reflection-on-mobile-applications-for-blood-pressure-management-a-systematic-review-on-potential-effects-and-initiatives
#6
Reyhaneh Mohammadi, Movahhedeh Ayatolahi Tafti, Soodabeh Hoveidamanesh, Reza Ghanavati, Omid Pournik
INTRODUCTION: Ischemic heart disease and stroke have been considered as the first global leading cause of death in last decades [1]. Blood pressure (BP) management is one of the easiest ways suggested for preventing and controlling cardiovascular diseases before the patient develops complications and death-following outcomes. Appearance of technology advancements in the health system has motivated researchers and health providers to study its different aspects and applications in order to improve disease prevention and management...
2018: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/29677137/phages-make-for-jolly-good-stories
#7
Thomas Häusler
Phage therapy has an intriguing history. It was widely used from the 1920s until the 1940s. After this period, it was nearly completely forgotten in the Western world, while it continued to be used in the Soviet part of the globe. The study of the history of phage therapy provides valuable input into the present development of the field. Science journalists uncovered much of this history and played an important role in the communication of phage therapy after the fall of the Soviet Union, when it came to the attention of Western researchers and doctors...
April 20, 2018: Viruses
https://www.readbyqxmd.com/read/29676113/-research-on-pharmacometabolomics
#8
REVIEW
Zhi-Xin Zhang, Xiao-Yan Gao
Pharmacometabolomics is a new and rapidly growing field in life science, which use metabolomics for studying drug effects and variation in drug response. Recently, it has been widely used in individualized medicine research. The research process of pharmacometabolomic can be divided into three parts: metabolomic study of baseline samples, drug response analysis after drug administration and statistical analysis. By combining the baseline information on metabotype of an individual with the drug response phenotype after drug exposure, pharmacometabolomic method can be used to predict the efficacy and toxicity of drugs, which providing the theoretical basis for individualized medical treatment...
March 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29673360/identifying-barriers-for-out-of-hospital-emergency-care-in-low-and-low-middle-income-countries-a-systematic-review
#9
Antony Gatebe Kironji, Peter Hodkinson, Sarah Stewart de Ramirez, Trisha Anest, Lee Wallis, Junaid Razzak, Alexander Jenson, Bhakti Hansoti
BACKGROUND: Out-of-hospital emergency care (OHEC), also known as prehospital care, has been shown to reduce morbidity and mortality from serious illness. We sought to summarize literature for low and low-middle income countries to identify barriers to and key interventions for OHEC delivery. METHODS: We performed a systematic review of the peer reviewed literature from January 2005 to March 2015 in PubMed, Embase, Cochrane, and Web of Science. All articles referencing research from low and low-middle income countries addressing OHEC, emergency medical services, or transport/transfer of patients were included...
April 19, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29673261/medical-surgical-and-wound-care-management-of-ulcerated-infantile-hemangiomas-a-systematic-review
#10
Jane Y Wang, Arvin Ighani, Ana P Ayala, Sadanori Akita, Irene Lara-Corrales, Afsaneh Alavi
Ulcerated infantile hemangiomas may present a therapeutic challenge, especially if there is concurrent hemorrhage or infection. The aim of this study was to systematically review the published evidence on the treatment of ulcerated hemangiomas, focusing on wound healing as the outcome of interest. We searched MEDLINE, Embase, SCOPUS, Cumulative Index to Nursing and Allied Health Literature (CINAHL), and Web of Science from inception to July 2016. Seventy-seven studies met our inclusion criteria. One study was a randomized controlled trial, 30 were observational studies, and 46 were case reports or case series...
April 1, 2018: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29672772/key-barriers-to-gout-care-a-systematic-review-and-thematic-synthesis-of-qualitative-studies
#11
Sharan K Rai, Hyon K Choi, Sally H J Choi, Anne F Townsend, Kam Shojania, Mary A De Vera
Objectives: Gout care remains highly suboptimal, contributing to an increased global disease burden. To understand barriers to gout care, our aim was to provide a systematic review and thematic synthesis of qualitative studies worldwide reporting provider and patient perspectives and experiences with management. Methods: We conducted a mapped search of MEDLINE, EMBASE, Cumulative Index to Nursing and Allied Health Literature, and Social Sciences Citation Index databases and selected qualitative studies of provider and patient perspectives on gout management...
April 17, 2018: Rheumatology
https://www.readbyqxmd.com/read/29672470/developments-in-the-transition-from-animal-use-to-simulation-based-biomedical-education
#12
John B Pawlowski, David M Feinstein, Shalin G Gala
There has been a significant shift from the use of animals in biomedical training exercises toward simulation-based education methods. The transition has been driven by technological advances, empirical evidence of improved student outcomes, cost-effectiveness, and a growing concern for the welfare of animals. These factors have spurred policy changes worldwide in how medical and science curricula are delivered. We detail how some of these policy changes evolved and comment on the future direction of simulation-based education and its implications for healthcare providers, instructors, and the general public...
April 18, 2018: Simulation in Healthcare: Journal of the Society for Simulation in Healthcare
https://www.readbyqxmd.com/read/29671445/demonstration-of-cellular-imaging-by-using-luminescent-and-anti-cytotoxic-europium-doped-hafnia-nanocrystals
#13
Irene Villa, Chiara Villa, Angelo Monguzzi, Vladimir Babin, Elena Tervoort, Martin Nikl, Markus Niederberger, Yvan Torrente, Anna Vedda, Alessandro Lauria
Luminescent nanoparticles are researched for their potential impact in medical science, but no materials approved for parenteral use have been available so far. To overcome this issue, we demonstrate that Eu3+-doped hafnium dioxide nanocrystals can be used as non-toxic, highly stable probes for cellular optical imaging and as radiosensitive materials for clinical treatment. Furthermore, viability and biocompatibility tests on artificially stressed cell cultures reveal their ability to buffer reactive oxygen species, proposing an anti-cytotoxic feature interesting for biomedical applications...
April 19, 2018: Nanoscale
https://www.readbyqxmd.com/read/29670027/a-review-of-evidence-for-a-therapeutic-application-of-traditional-japanese-kampo-medicine-for-oral-diseases-disorders
#14
REVIEW
Marie-Pier Veilleux, Satomi Moriyama, Masami Yoshioka, Daisuke Hinode, Daniel Grenier
Kampo medicines prescribed by specialized medical practitioners and Japanese physicians have gradually reemerged in Japan as alternatives to Western medications. Kampo formulations are composed of several plant extracts and, as such, the broad variety of phytochemicals they contain likely act synergistically to provide their beneficial effects. Kampo medicines have traditionally been prescribed for a number of health conditions, including chronic hepatitis, bronchial asthma, anemia, etc. The aim of this article is to review the beneficial effects of Kampos with respect to oral health...
April 18, 2018: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/29669703/physical-activity-sedentary-behavior-and-diet-related-ehealth-and-mhealth-research-bibliometric-analysis
#15
REVIEW
Andre Matthias Müller, Carol A Maher, Corneel Vandelanotte, Melanie Hingle, Anouk Middelweerd, Michael L Lopez, Ann DeSmet, Camille E Short, Nicole Nathan, Melinda J Hutchesson, Louise Poppe, Catherine B Woods, Susan L Williams, Petra A Wark
BACKGROUND: Electronic health (eHealth) and mobile health (mHealth) approaches to address low physical activity levels, sedentary behavior, and unhealthy diets have received significant research attention. However, attempts to systematically map the entirety of the research field are lacking. This gap can be filled with a bibliometric study, where publication-specific data such as citations, journals, authors, and keywords are used to provide a systematic overview of a specific field...
April 18, 2018: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29669066/does-health-informatics-have-a-replication-crisis
#16
Enrico Coiera, Elske Ammenwerth, Andrew Georgiou, Farah Magrabi
Objective: Many research fields, including psychology and basic medical sciences, struggle with poor reproducibility of reported studies. Biomedical and health informatics is unlikely to be immune to these challenges. This paper explores replication in informatics and the unique challenges the discipline faces. Methods: Narrative review of recent literature on research replication challenges. Results: While there is growing interest in re-analysis of existing data, experimental replication studies appear uncommon in informatics...
April 13, 2018: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/29669005/fertility-and-neonatal-outcomes-of-embryos-achieving-blastulation-on-day-7-are-they-of-clinical-value
#17
Tong Du, Yun Wang, Yong Fan, Shiyi Zhang, Zhiguang Yan, Weina Yu, Qianwen Xi, Qiuju Chen, Ben W Mol, Qifeng Lyu, Yanping Kuang
STUDY QUESTION: Is transferring embryos that achieve blastulation on Day 7 effective and safe? SUMMARY ANSWER: Embryos that achieve blastulation on Day 7 resulted in clinically relevant rates of clinical pregnancy (32.5%) and live birth (25.2%), and newborns have a similar risk of low birth weight, congenital malformations or early neonatal death compared with those derived from Days 5 and 6 blastocysts. WHAT IS KNOWN ALREADY: Potential advantages of blastocyst transfer over cleavage embryo transfer have led to a shift toward the former in IVF practice...
April 13, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29668523/academic-medical-centers-as-innovation-ecosystems-evolution-of-industry-partnership-models-beyond-the-bayh-dole-act
#18
Patrick J Silva, Kenneth S Ramos
Innovation ecosystems tied to academic medical centers (AMCs) are inextricably linked to policy, practices, and infrastructure resulting from the passage of the Bayh-Dole Act in 1980. Bayh-Dole smoothed the way to patenting and licensing new drugs, and to some degree, medical devices and diagnostic reagents. Property rights under Bayh-Dole provided a significant incentive for industry investments in clinical trials, clinical validation, and industrial scale-up of products that advanced health care. Bayh-Dole amplified private investment in biotechnology drug development, and from the authors' perspective did not significantly interfere with the ability of AMCs to produce excellent peer-reviewed science...
April 17, 2018: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/29668483/the-use-of-smartphone-in-medical-practice
#19
REVIEW
Nada Pop-Jordanova, Mario Loleski, Sofija Loleska
In this review we present some data about the use of mobile phones in medical practice. The results of over hundred studies cited in PubMed during the last few years have been discussed. The article gives background connected with a project in the Macedonian Academy of Sciences and Arts referring to a personal mobile phone application named "Neurogame" which is currently constructed to evaluate motor skills related to attention and concentration in different samples of people.
December 1, 2017: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://www.readbyqxmd.com/read/29668466/50-years-of-the-macedonian-academy-of-sciences-and-arts-1967-2017-and-48-years-of-publishing-the-journal-prilozi-contributions-of-masa
#20
Momir Polenakovic, Nada Pop-Jordanova, Zoran Gucev
Papers on medical subjects have been published since the first issue of the journal Prilozi in 1969, totalling a number of of 957 (nine hundred and fifty seven) papers have been published in Prilozi. Two hundred and twenty nine cover subjects on natural sciences and mathematics, and 728 (seven hundred and twenty eight) subjects on medical sciences. So far, 2017 No. XXXVIII-2, 622 (six hundred and twenty two) papers published in Prilozi are in Pubmed. Prilozi is published three times a year and it is covered by the following services: Baidu Scholar, Case, Celdes, CNKI Scholar (China National Knowledge Infrastructure), CNPIEC, DOAJ (Directory of Open Access Journals), EBSCO (relevant databases), EBSCO Discovery Service, Elsevier - SCOPUS, Google Scholar, J-Gate, JournalTOCs, KESLI-NDSL (Korean National Discovery for Science Leaders), Naviga (Softweco), Primo Central (ExLibris), Publons, PubMed, ReadCube, ResearchGate, SCImago (SJR), Summon (Serials Solutions/ProQuest), TDNet, Ulrich's Periodicals Directory/ulrichsweb WanFang Data, WorldCat (OCLC)...
December 1, 2017: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
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