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https://www.readbyqxmd.com/read/29142474/clinical-features-of-alcoholic-hepatitis-in-latinos-and-caucasians-a-single-center-experience
#1
Rogelio Pinon-Gutierrez, Blythe Durbin-Johnson, Charles H Halsted, Valentina Medici
AIM: To study differences of presentation, management, and prognosis of alcoholic hepatitis in Latinos compared to Caucasians. METHODS: We retrospectively screened 876 charts of Caucasian and Latino patients who were evaluated at University of California Davis Medical Center between 1/1/2002-12/31/2014 with the diagnosis of alcoholic liver disease. We identified and collected data on 137 Caucasians and 64 Latinos who met criteria for alcoholic hepatitis, including chronic history of heavy alcohol use, at least one episode of jaundice with bilirubin ≥ 3...
October 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29142192/successful-post-transplant-psychiatric-interventions-during-long-term-follow-up-of-patients-receiving-liver-transplants-for-alcoholic-liver-disease
#2
Hiroyuki Kimura, Yasuharu Onishi, Shinichi Kishi, Nobuhiko Kurata, Satoshi Ogiso, Hideya Kamei, Chisato Tsuboi, Naoko Yamaguchi, Azusa Shiga, Mai Kondo, Yushun Yokoyama, Fumika Takasato, Hiroshige Fujishiro, Kanako Ishizuka, Takashi Okada, Yasuhiro Ogura, Norio Ozaki
BACKGROUND Around 20-30% of patients who undergo liver transplantation (LT) for alcoholic liver disease (ALD) will resume heavy drinking after LT. It is crucial to control post-transplant relapse of alcohol use, because alcoholic recidivism has been shown to have a negative impact on post-transplant compliance and long-term outcomes of LT recipients. However, there is currently no specific, effective psychiatric intervention for preventing additional alcohol consumption in clinical practice. CASE REPORT We present 3 patients who underwent LT for ALD at Nagoya University Hospital who were followed up for prolonged periods (7...
November 16, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/29141613/determinants-of-patient-satisfaction-following-reconstructive-shoulder-surgery
#3
Sascha J Baettig, Karl Wieser, Christian Gerber
BACKGROUND: Obtaining patient satisfaction is a key goal of surgical treatment. It was the purpose of this study to identify pre-, peri- and postoperative factors determining patient satisfaction after shoulder surgery, quantify their relative importance and thereby allow the surgeon to focus on parameters, which will influence patient satisfaction. METHODS: We retrospectively reviewed 505 patients, who underwent either rotator cuff repair (n = 216) or total shoulder arthroplasty (n = 289)...
November 15, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29140988/sex-difference-in-the-interaction-of-alcohol-intake-hepatitis-b-virus-and-hepatitis-c-virus-on-the-risk-of-cirrhosis
#4
Tommaso Stroffolini, Evangelista Sagnelli, Angelo Andriulli, Guido Colloredo, Caterina Furlan, Giovanni Battista Gaeta, Filomena Morisco, Mario Pirisi, Floriano Rosina, Caterina Sagnelli, Antonina Smedile, Piero Luigi Almasio
BACKGROUND: The joint effect of the interaction of alcohol intake, hepatitis B virus (HBV) and hepatitis C virus (HCV) on the risk of cirrhosis is still unexplored because a large sample size is required for this investigation. OBJECTIVE: Evaluation of interaction of HBV, HCV and alcohol abuse on the risk of cirrhosis. DESIGN: We analysed 12,262 consecutive patients with chronic liver disease of various aetiologies referring to 95 Italian liver units in 2001 or 2014...
2017: PloS One
https://www.readbyqxmd.com/read/29137173/psychiatric-disorders-differently-correlate-with-physical-self-rated-health-across-ethnic-groups
#5
Shervin Assari
In this study, we compared 10 ethnic groups for associations between psychiatric disorders and physical self-rated health (SRH) in the United States. Data came from the Collaborative Psychiatric Epidemiology Surveys (CPES), 2001-2003. The study included 7587 non-Latino White, 4746 African American, 1442 Mexican, 1106 other Hispanic, 656 other Asian, 600 Chinese, 577 Cuban, 520 Vietnamese, 508 Filipino, and 495 Puerto Rican individuals. The Composite International Diagnostic Interview (CIDI) was used to measure psychiatric disorders, including major depressive disorder (MDD), general anxiety disorder (GAD), social phobia, panic disorder, post-traumatic stress disorder (PTSD), alcohol abuse, and binge eating disorders...
November 13, 2017: Journal of Personalized Medicine
https://www.readbyqxmd.com/read/29136757/muscone-exerts-protective-roles-on-alcohol-induced-osteonecrosis-of-the-femoral-head
#6
Yan-Jie Guo, Shi-Hua Luo, Ming-Jie Tang, Zu-Bin Zhou, Jun-Hui Yin, You-Shui Gao, Xiao-Qian Dang
Long-term alcohol abuse causes musculoskeletal disorders, among of which, alcohol-induced osteonecrosis of the femoral head (ONFH) is of concern due to its significant and severe complications. A variety of methods have been attempted to prevent alcohol-induced ONFH, and monomers extracted from Chinese herbs might benefit the disease profoundly. In the current study, muscone, the main ingredient of musk, was used to prevent alcohol-induced ONFH. In vitro, ethanol was used to affect the potential of osteogenesis and proliferation of human bone mesenchymal stem cells (hBMSCs), and beneficial role of muscone was investigated on hBMSCs...
November 6, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29136100/ghrelin-is-related-to-personality-differences-in-reward-sensitivity-and-impulsivity
#7
Elizabeth Ralevski, Marya Shanabrough, Jenelle Newcomb, Erin Gandelman, Ryan Hayden, Tamas L Horvath, Ismene Petrakis
Aims: Ghrelin, a feeding-related peptide mainly produced in the stomach, has been linked to reward mechanisms for food and drugs of abuse in addition to traits of impulsivity. This study is a secondary analysis of an existing data set designed to examine the direct relationships between fasting ghrelin levels and reward sensitivity/impulsivity in healthy social drinkers. Methods: Participants (n = 20) were recruited from an original study examining the subjective effects of alcohol among social drinkers...
November 9, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/29135074/effects-of-alcohol-on-plasma-glucose-and-prevention-of-alcohol-induced-hypoglycemia-in-type-1-diabetes-a-systematic-review-with-grade
#8
REVIEW
R Tetzschner, K Nørgaard, A Ranjan
BACKGROUND: Since ethanol is thought to be a risk factor for severe hypoglycemia, patients with type 1 diabetes (T1D) are recommended to limit ethanol intake. However, little is known on how ethanol affects plasma glucose and how ethanol-induced hypoglycemia can be prevented. In this study, we systematically reviewed the literature for ethanol effects on plasma glucose and for prevention strategies on ethanol-induced hypoglycemia. METHODS: Electronic searches on PubMed and Google were conducted in February 2017...
November 14, 2017: Diabetes/metabolism Research and Reviews
https://www.readbyqxmd.com/read/29133319/identification-of-factors-associated-with-resilience-in-medical-students-through-a-cross-sectional-census
#9
Anna Christina Pinho de Oliveira, André Paes Goulart Machado, Renata Nunes Aranha
OBJECTIVES: Research on resilience has been gaining momentum, and it has already been shown that increased resilience creates positive changes at the individual and collective levels. Understanding of the factors associated with resilience may guide specific actions directed towards different populations. The objective of this study was to investigate these associated factors within a population of medical students. DESIGN: Cross-sectional census. SETTING: A public medical school in the state of Rio de Janeiro, Brazil...
November 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/29132291/hiv-prevention-needs-for-men-who-have-sex-with-men-in-swaziland
#10
Bhekie Sithole
Men who have sex with men (MSM) have a high HIV burden and also often face multiple other challenges accessing HIV services, including legal and social issues. Although Swaziland recently started responding with interventions for MSM, significant gaps still exist both in information and programming. This study aimed to explore the HIV prevention needs of MSM in Swaziland, including factors elevating their risks and vulnerabilities to HIV infection; to find out what HIV prevention strategies exist; and to determine how best to meet the prevention needs of MSM...
December 2017: African Journal of AIDS Research: AJAR
https://www.readbyqxmd.com/read/29130694/initial-validation-of-brief-measures-of-suicide-risk-factors-common-data-elements-used-by-the-military-suicide-research-consortium
#11
Fallon B Ringer, Kelly A Soberay, Megan L Rogers, Christopher R Hagan, Carol Chu, Matt Schneider, Matthew C Podlogar, Tracy Witte, Jill Holm-Denoma, E Ashby Plant, Peter M Gutierrez, Thomas E Joiner
The Military Suicide Research Consortium (MSRC) developed a 57-item questionnaire assessing suicide risk factors, referred to as the Common Data Elements (CDEs), in order to facilitate data sharing and improve collaboration across independent studies. All studies funded by MSRC are required to include the CDEs in their assessment protocol. The CDEs include shortened measures of the following: current and past suicide risk, lethality and intent of past suicide attempts, hopelessness, thwarted belongingness, anxiety sensitivity, posttraumatic stress disorder symptoms, traumatic brain injury, insomnia, and alcohol abuse...
November 13, 2017: Psychological Assessment
https://www.readbyqxmd.com/read/29129682/spatial-and-sex-dependent-responses-of-adult-endogenous-neural-stem-cells-to-alcohol-consumption
#12
Erica L McGrath, Junling Gao, Yong-Fang Kuo, Tiffany J Dunn, Moniqua J Ray, Kelly T Dineley, Kathryn A Cunningham, Bhupendra S Kaphalia, Ping Wu
Chronic alcohol abuse results in alcohol-related neurodegeneration, and critical gaps in our knowledge hinder therapeutic development. Neural stem cells (NSCs) are a subpopulation of cells within the adult brain that contribute to brain maintenance and recovery. While it is known that alcohol alters NSCs, little is known about how NSC response to alcohol is related to sex, brain region, and stage of differentiation. Understanding these relationships will aid in therapeutic development. Here, we used an inducible transgenic mouse model to track the stages of differentiation of adult endogenous NSCs and observed distinct NSC behaviors in three brain regions (subventricular zone, subgranular zone, and tanycyte layer) after long-term alcohol consumption...
November 3, 2017: Stem Cell Reports
https://www.readbyqxmd.com/read/29129191/alcohol-use-disorders-are-associated-with-increased-hiv-risk-behaviors-in-cocaine-dependent-methadone-patients
#13
Steven E Meredith, Carla J Rash, Nancy M Petry
People who inject drugs (PWID) are at increased risk of HIV infection. Although methadone maintenance therapy can help lower this risk, many methadone patients continue to engage in HIV risk behaviors, especially patients who use cocaine and alcohol. The purpose of the current study was to investigate relations between alcohol use disorders and HIV risk behavior in 239 cocaine-dependent methadone patients participating in a randomized controlled trial of a behavioral intervention to promote cocaine abstinence...
December 2017: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/29128903/impairment-of-thiamine-transport-at-the-gut-bbb-axis-contributes-to-wernicke-s-encephalopathy
#14
P M Abdul-Muneer, Saleena Alikunju, Heather Schuetz, Adam M Szlachetka, Xiaotang Ma, James Haorah
Wernicke's encephalopathy, a common neurological disease, is caused by thiamine (vitamin B1) deficiency. Neuropathy resulting from thiamine deficiency is a hallmark of Wernicke-Korsakoff syndrome in chronic alcohol users. The underlying mechanisms of this deficiency and progression of neuropathy remain to be understood. To uncover the unknown mechanisms of thiamine deficiency in alcohol abuse, we used chronic alcohol consumption or thiamine deficiency diet ingestion in animal models. Observations from animal models were validated in primary human neuronal culture for neurodegenerative process...
November 11, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/29128624/wernicke-korsakoff-syndrome-complicated-by-subacute-beriberi-neuropathy-in-an-alcoholic-patient
#15
Salvatore Di Marco, Laura Pilati, Filippo Brighina, Brigida Fierro, Giuseppe Cosentino
Thiamine (vitamin B1) deficiency is a common condition in alcohol abusers, which can lead to damage of both the peripheral and the central nervous systems. Here we describe the case of an alcoholic patient who presented with acute onset of ataxia, severe weakness of the four limbs, and hypoesthesia and dysesthesia of the distal portion of the upper and lower extremities. The clinical picture also included mental confusion and amnesia. A diagnosis of Wernicke-Korsakoff syndrome was made based on clinical symptoms and brain RMI findings...
November 8, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29128307/rescue-of-glutamate-transport-in-the-lateral-habenula-alleviates-depression-and-anxiety-like-behaviors-in-ethanol-withdrawn-rats
#16
Seungwoo Kang, Jing Li, Alex Bekker, Jiang-Hong Ye
Alcoholism and psychiatric disorders like depression and anxiety are often comorbid. Although the mechanisms underlying this comorbidity are unclear, emerging evidence suggests that maladaptation of the glial glutamate transporter GLT-1 may play a role. Findings from animal and human studies have linked aversive states, including those related to drugs of abuse and depression, to aberrant activity in the lateral habenula (LHb). The relationship between GLT-1 maladaptation, LHb activity, and abnormal behaviors related to alcohol withdrawal, however, remains unknown...
November 8, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/29127890/the-role-of-ethyl-glucuronide-in-supporting-medico-legal-investigations-analysis-of-this-biomarker-in-different-postmortem-specimens-from-21-selected-autopsy-cases
#17
Anna Laura Santunione, Patrizia Verri, Filippo Marchesi, Cecilia Rustichelli, Federica Palazzoli, Daniele Vandelli, Manuela Licata, Enrico Silingardi
Ethanol determination in postmortem blood is one of the most frequently requested analyses in legal medicine and forensic toxicology. Ethyl glucuronide is a non-oxidative ethanol metabolite. It is also a useful marker of ante-mortem alcohol ingestion when ethanol itself has been completely eliminated from the body and could be considered in autopsy cases to obtain more reliable indications. The aim of the present study was to investigate the ethyl glucuronide distribution in postmortem specimens from autopsy cases found to be positive for ethanol...
November 1, 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/29125942/conditions-for-addressing-environmental-determinants-of-health-behavior-in-intersectoral-policy-networks-a-fuzzy-set-qualitative-comparative-analysis
#18
D T J M Peters, S Verweij, K Grêaux, K Stronks, J Harting
Improving health requires changes in the social, physical, economic and political determinants of health behavior. For the realization of policies that address these environmental determinants, intersectoral policy networks are considered necessary for the pooling of resources to implement different policy instruments. However, such network diversity may increase network complexity and therefore hamper network performance. Network complexity may be reduced by network management and the provision of financial resources...
September 1, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/29125383/depression-and-substance-use-towards-the-development-of-an-emotion-regulation-model-of-stigma-coping
#19
Katie Wang, Charles L Burton, John E Pachankis
The comorbidity between depression and substance use problems is well-documented, yet little research has investigated how stigma associated with one's depression might relate to alcohol and drug use. The current study examined the association between depression-related stigma and substance use coping and considered the role of emotion dysregulation (i.e., difficulty in monitoring, evaluating, and modulating one's emotional reactions) as a mechanism underlying this association. A sample of individuals who self-identified as having current or remitted depression (N = 218) completed self-report measures of depression-related stigma, emotion dysregulation, and tendency to rely on alcohol or drugs to cope with psychological distress...
November 10, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/29122225/-web-visit-patterns-for-the-clinical-practice-guidelines-for-management-of-depressive-disorder-and-alcohol-abuse-dependence
#20
Fernando Suárez-Obando, Carlos Gómez Restrepo
INTRODUCTION: Clinical practice guidelines (CPG) are a set of recommendations for professionals, patients, and families, in order to make decisions about health care. The CPG respond to the need for concise, accurate, practical, and up to date information. In the field of mental health, Colombia has developed three GPC; alcohol (GPC-OH), depression (GPC-TDA), and schizophrenia. OBJECTIVES: To describe the Web Portal traffic related to psychiatry guidelines, with emphasis on the number of visits, distribution throughout Colombian cities, and estimating user behaviour patterns...
October 2017: Revista Colombiana de Psiquiatría
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