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functional constipation

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https://www.readbyqxmd.com/read/29773453/a-structured-bowel-management-program-for-patients-with-severe-functional-constipation-can-help-decrease-emergency-department-visits-hospital-admissions-and-healthcare-costs
#1
Carlos A Reck-Burneo, Alejandra Vilanova-Sanchez, Alessandra C Gasior, Alexander J M Dingemans, Victoria A Lane, Robert Dyckes, Onnalisa Nash, Laura Weaver, Tassiana Maloof, Richard J Wood, Sarah Zobell, Michael D Rollins, Marc A Levitt
BACKGROUND: Published health-care costs related to constipation in children in the USA are estimated at $3.9 billion/year. We sought to assess the effect of a bowel management program (BMP) on health-care utilization and costs. METHODS: At two collaborating centers, BMP involves an outpatient week during which a treatment plan is implemented and objective assessment of stool burden is performed with daily radiography. We reviewed all patients with severe functional constipation who participated in the program from March 2011 to June 2015 in center 1 and from April 2014 to April 2016 in center 2...
March 24, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29768343/potential-common-factors-associated-with-predisposition-to-common-cold-in-middle-aged-and-elderly-japanese-a-community-based-cross-sectional-study
#2
Michi Shibata, Taizo Iwane, Ryoko Higuchi, Kaname Suwa, Kei Nakajima
People worldwide frequently catch a common cold, which occasionally develops into secondary severe conditions such as pneumonia. However, it is unclear whether predisposition to the common cold is associated with the individual's characteristics including age, body weight, lifestyles, diets, and intestinal functions, besides exposure to a responsible pathogen. We addressed this issue epidemiologically considering many relevant clinical factors.We reviewed data from a cross-sectional study consisting of 39,524 apparently healthy Japanese aged 40 to 79 years (26,975 men and 12,549 women) who underwent a checkup in 2007...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29760783/minor-digestive-symptoms-and-their-impact-in-the-general-population-a-cluster-analysis-approach
#3
Diane L'Heureux-Bouron, Sophie Legrain-Raspaud, Helen R Carruthers, P J Whorwell
Background: The classification and treatment of patients who do not meet the criteria for a functional gastrointestinal (GI) disorder has not been well established. This study aimed to record the prevalence of minor digestive symptoms (MDSs) in the general population attempting to divide them into symptom clusters as well as trying to assess their impact and the way sufferers cope with them. Methods: Following face-to-face interviews, a web-based, self-administered questionnaire was designed to capture a range of GI sensations using 34 questions and 12 images depicting abdominal symptoms...
2018: Therapeutic Advances in Gastroenterology
https://www.readbyqxmd.com/read/29759035/a-novel-missense-mutation-in-slc5a5-gene-in-a-sudanese-family-with-congenital-hypothyroidism
#4
Yui Watanabe, Reham Shareef Ebrhim, Mohamed A Abdullah, Roy E Weiss
Thyroid hormone synthesis requires the presence of iodide. The sodium iodide symporter (NIS) is a glycoprotein which mediates the active uptake of iodide from the blood stream into the thyroid grand. NIS defects due to SLC5A5 gene mutations are known to cause congenital hypothyroidism (CH). The proposita is a 28-year-old female whose origin is the North Sudan where neonatal screening for CH is not available. She presented with severe constipation and a goiter at the age of 40 days. Laboratory testing confirmed CH and she was started on levothyroxine (L-T4)...
May 15, 2018: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/29755994/therapeutic-effects-of-low-dose-bismuth-subcitrate-on-symptoms-and-health-related-quality-of-life-in-adult-patients-with-irritable-bowel-syndrome-a-clinical-trial
#5
Hamed Daghaghzadeh, Ardalan Memar, Yasaman Mohamadi, Nooshin Rezakhani, Parastoo Safazadeh, Sarina Aghaha, Payman Adibi
Objective: Irritable bowel syndrome (IBS) is a chronic functional disorder of the gastrointestinal tract that causes abdominal pain or discomfort and alters bowel with no organic abnormalities. Treatment options for IBS have increased in number in the past decade, and clinicians should not be limited to use only conventional treatments to cure it. This article is a placebo-controlled clinical trial to assess the therapeutic effects of low-dose bismuth subcitrate on symptoms and the health-related quality of life in adult patients with IBS...
January 2018: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/29754864/adherence-to-polyethylene-glycol-treatment-in-children-with-functional-constipation-is-associated-with-parental-illness-perceptions-satisfaction-with-treatment-and-perceived-treatment-convenience
#6
Ilan Jasper Nader Koppen, Elsa A van Wassenaer, Rinse W Barendsen, Paul L Brand, Marc A Benninga
OBJECTIVES: To assess treatment adherence in children with functional constipation and to evaluate the association with parental beliefs about medication, illness perceptions, treatment satisfaction, and satisfaction with information about medication. STUDY DESIGN: A cross-sectional survey was administered among parents of children with functional constipation treated with polyethylene glycol. Adherence was measured via the Medication Adherence Report Scale (MARS-5, score 5-25), with greater scores indicating better adherence (scores ≥23 were defined as adherent)...
May 10, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29752611/comparison-of-electroacupuncture-and-mild-warm-moxibustion-on-brain-gut-function-in-patients-with-constipation-predominant-irritable-bowel-syndrome-a-randomized-controlled-trial
#7
Ji-Meng Zhao, Jin-Hua Lu, Xiao-Jun Yin, Lu-Yi Wu, Chun-Hui Bao, Xing-Kui Chen, Yue-Hua Chen, Wei-Jun Tang, Xiao-Ming Jin, Huan-Gan Wu, Yin Shi
OBJECTIVE: To compare the effects of electroacupuncture (EA) and mild-warm moxibustion (Mox) therapies for constipation-predominant irritable bowel syndrome (C-IBS) patients. METHODS: Sixty C-IBS patients were assigned to 2 groups by simple randomized method, i.e. EA group (30 cases) and Mox group (30 cases). Both EA and Mox treatments were performed on bilateral Tianshu (ST 25) and Shangjuxu (ST 37) for 30 min each time, 6 times per week, for 4 consecutive weeks...
May 2018: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29750283/constipation-management-in-pediatric-primary-care
#8
Leah Khan
Constipation is a common and often difficult to manage problem encountered in outpatient primary care. Although we give our patients many different modalities to treat constipation (eg, diet changes, behavior modification, probiotics, medication), there is little evidence to support any of these modalities. We also tend to order unnecessary tests during the diagnostic process. This article tries to clarify the diagnostic process and provide a clear treatment path to be used for functional constipation. [Pediatr Ann...
May 1, 2018: Pediatric Annals
https://www.readbyqxmd.com/read/29749705/fecal-clostridiales-distribution-and-short-chain-fatty-acids-reflect-bowel-habits-in-irritable-bowel-syndrome
#9
Giorgio Gargari, Valentina Taverniti, Claudio Gardana, Cesare Cremon, Filippo Canducci, Isabella Pagano, Maria Raffaella Barbaro, Lara Bellacosa, Anna Maria Castellazzi, Chiara Valsecchi, Sara Carlotta Tagliacarne, Massimo Bellini, Lorenzo Bertani, Dario Gambaccini, Santino Marchi, Michele Cicala, Bastianello Germanà, Elisabetta Dal Pont, Maurizio Vecchi, Cristina Ogliari, Walter Fiore, Vincenzo Stanghellini, Giovanni Barbara, Simone Guglielmetti
Irritable bowel syndrome (IBS), a common functional gastrointestinal disorder, is classified according to bowel habits as IBS with constipation (IBS-C), with diarrhea (IBS-D), with alternating constipation and diarrhea (IBS-M), and unsubtyped (IBS-U). The mechanisms leading to the different IBS forms are mostly unknown. This study aims to evaluate whether specific fecal bacterial taxa and/or short-chain fatty acids (SCFAs) can be used to distinguish IBS subtypes and are relevant for explaining the clinical differences between IBS sub-categories...
May 11, 2018: Environmental Microbiology
https://www.readbyqxmd.com/read/29749329/is-celiac-disease-misdiagnosed-in-children-with-functional-constipation
#10
Sezin Akman, Özlem Şahaloğlu, Ceyhun Dalkan, Nerin Nadir Bahçeciler, Çiğdem Arıkan
BACKGROUND/AIMS: Functional constipation is one of the common problems in childhood, and it comprises approximately 5% of the pediatric outpatient clinical applications. On the other hand, celiac disease (CD) is an immune enteropathy with the prevalence between 1/150 and 1/200. In addition to the classical symptoms of the disease such as diarrhea and weight loss, the incidence of atypical symptoms is increasing. This study aims to determine the prevalence of CD in patients with chronic constipation...
March 2018: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
https://www.readbyqxmd.com/read/29746169/preventive-effects-of-transcutaneous-electrical-acustimulation-on-ischemic-stroke-induced-constipation-mediated-via-the-autonomic-pathway
#11
Zhaoxiu Liu, Yebo Ge, Feng Xu, Yuemei Xu, Yanmei Liu, Feizhen Xia, Lin Lin, Jiande Dz Chen
AIM: To explore the preventive effect and possible mechanisms of transcutaneous electrical acustimulation (TEA) on stroke-induced constipation. METHODS: A total of 86 ischemic stroke patients were randomly allocated to 2-week TEA or sham-TEA group. Bowel dairy and Bristol Stool Form Scale were recorded daily. Constipation and dyspeptic symptom assessment was performed at the end of the 14-day treatment. Electrocardiogram was recorded for the assessment of autonomic function...
May 10, 2018: American Journal of Physiology. Gastrointestinal and Liver Physiology
https://www.readbyqxmd.com/read/29745439/cannabinoids-and-gastrointestinal-motility-pharmacology-clinical-effects-and-potential-therapeutics-in-humans
#12
REVIEW
M Camilleri
BACKGROUND: Cannabinoid agents and cannabis are frequently used for relief of diverse gastrointestinal symptoms. PURPOSE: The objective of this article is to increase the awareness of gastroenterologists to the effects of cannabinoids on gastrointestinal motility, as gastroenterologists are likely to encounter patients who are taking cannabinoids, or those with dysmotility that may be associated with cannabinoid mechanisms. The non-selective cannabinoid agonist, dronabinol, retards gastric emptying and inhibits colonic tone and phasic pressure activity...
May 10, 2018: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/29745332/interactions-of-dietary-fiber-with-nutritional-components-on-gut-microbial-composition-function-and-health-in-monogastrics
#13
A Seidu, Che Dongsheng, Qin Guixin, Jiang Hailong, Rui Han, Cornelius Tlotliso Sello
The relation between dietary fiber and wellbeing of human and other monogastrics has recently became a hot topic as showed in an increasing number of publication of the related research. The aim of this review is to describe through a logical approach the scientific suggestion linking possible benefits of dietary fiber on nutritional components and their effect on the gastrointestinal composition in relation to disease conditions in humans or animals. Dietary fiber plays a key role in influencing blood glucose or insulin concentrations, stool bulkiness, reduce the pH within the digestive tract, synthesize volatile fatty acids (VFA), reduce intestinal transit time, stimulate growth of intestinal microbes, and constructively enhance various blood parameters...
May 7, 2018: Current Protein & Peptide Science
https://www.readbyqxmd.com/read/29742911/unmet-needs-in-pediatric-functional-constipation
#14
Manu Sood, Peter Lichtlen, Maria Claudia Perez
No abstract text is available yet for this article.
May 1, 2018: Clinical Pediatrics
https://www.readbyqxmd.com/read/29742718/efficacy-of-electroacupuncture-compared-with-transcutaneous-electric-nerve-stimulation-for-functional-constipation-study-protocol-for-a-randomized-controlled-trial
#15
Yuxiao Zeng, Xuecheng Zhang, Jing Zhou, Xinwei Wang, Ruimin Jiao, Zhishun Liu
BACKGROUND: To treat functional constipation, both electroacupuncture (EA) therapy and transcutaneous electric nerve stimulation (TENS) are safe and effective. However, no head-to-head comparison trial has been conducted. This trial compares the efficacy of electroacupuncture relative to transcutaneous electric nerve stimulation for functional constipation. METHODS: Individuals with functional constipation will be randomly allocated to receive either EA or TENS (n = 51, each), 3 times per week for 8 weeks...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29740204/oral-treatment-with-plecanatide-or-dolcanatide-attenuates-visceral-hypersensitivity-via-activation-of-guanylate-cyclase-c-in-rat-models
#16
Illona-Marie Boulete, Anusha Thadi, Catherine Beaufrand, Viren Patwa, Apoorva Joshi, John A Foss, E Priya Eddy, Helene Eutamene, Vaseem A Palejwala, Vassilia Theodorou, Kunwar Shailubhai
AIM: To investigate the effects of plecanatide and dolcanatide on maintenance of paracellular permeability, integrity of tight junctions and on suppression of visceral hypersensitivity. METHODS: Transport of fluorescein isothiocyanate (FITC)-dextran was measured to assess permeability across cell monolayers and rat colon tissues. Effects of plecanatide and dolcanatide on the integrity of tight junctions in Caco-2 and T84 monolayers and on the expression and localization of occludin and zonula occludens-1 (ZO-1) were examined by immunofluorescence microscopy...
May 7, 2018: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29736120/symptoms-in-bangladeshi-patients-with-incurable-cancers-implications-for-interventions
#17
Richard R Love, G M Tanimul Ahsan, Tahmina Ferdousy, Shamsun Nahar, Sheikh Iqbal Ahamed
Aims: The poor state of palliative care in low- and middle-income countries has been termed a global crisis by the Lancet Commission on Palliative Care. The investigators previously reported on a cross-sectional study of symptoms in 640 Bangladeshi adults with incurable cancers. Usual levels of pain were high. The not-reported details of pain and other symptoms offered an opportunity to consider explanations and implications for interventions to lessen these symptoms. Methods: At one visit, 640 Bangladeshi patients completed a symptom questionnaire...
April 2018: Indian Journal of Palliative Care
https://www.readbyqxmd.com/read/29733520/mango-mangifera-indica-l-polyphenols-ameliorate-functional-constipation-symptoms-in-humans-beyond-equivalent-amount-of-fiber
#18
Vinicius P Venancio, Hyemee Kim, Maritza A Sirven, Carmen D Tekwe, Gilson Honvoh, Stephen T Talcott, Susanne U Mertens-Talcott
SCOPE: Chronic constipation is a common gastrointestinal condition associated with intestinal inflammation and considerably impaired quality of life, affecting about 20% of Americans. Dietary fiber and laxatives aid in its treatment but do not fully address all symptoms, such as intestinal inflammation. Mango (Mangifera indica L.), a fiber- and polyphenol-rich fruit may provide anti-inflammatory effects in constipation. METHODS AND RESULTS: The 4-week consumption of mango fruit (300 g) or the equivalent amount of fiber was investigated in otherwise healthy human volunteers with chronic constipation that were randomly assigned to either group...
May 7, 2018: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/29729176/-comparative-characteristic-of-functional-gastrocerebral-disorders-in-donors-and-premature-infants
#19
Luydmila V Ignatko, Andriiana O Yankovska, Gabriela G Kavulya, Olena V Debretseni, Kristian O Debretseni, Nataliia M Hema-Bahyna, Agneta V Lenchenko
OBJECTIVE: Introduction: Functional gastrocerebral disorders (FGCD) occupy one of the leading places in the structure of diseases of digestive organs in young children. Functional gastrointestinal disorders are accompanied by various combinations of persistent or recurrent gastrointestinal symptoms without structural or biochemical disorders. They can accompany the normal development of the child and depend on organ's disorders on the background of autonomic dysfunction, psycho-emotional and humoral factors...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29719399/effectiveness-and-safety-of-oral-olanzapine-treatment-transitioned-from-rapid-acting-intramuscular-olanzapine-for-agitation-associated-with-schizophrenia
#20
Hideaki Katagiri, Masanori Taketsuna, Shinpei Kondo, Kenta Kajimoto, Etsuko Aoi, Yuka Tanji
Objective: To assess the effectiveness and safety of oral olanzapine treatment transitioned from rapid-acting intramuscular olanzapine (RAIM) in patients with acute agitation associated with schizophrenia in a real-world clinical setting. Methods: The postmarketing surveillance study with a 3-day observational period after the last RAIM administration was conducted (original study). Following this, an extended study was added for patients who received oral olanzapine after RAIM administration during the original study period, in order to additionally observe them for 7 days after initial RAIM administration...
2018: Neuropsychiatric Disease and Treatment
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