Hazel B Nichols, Mariaelisa Graff, Jeannette T Bensen, Kathryn L Lunetta, Katie M O'Brien, Melissa A Troester, Lindsay A Williams, Kristin Young, Chi-Chen Hong, Song Yao, Christopher A Haiman, Edward A Ruiz-Narváez, Christine B Ambrosone, Julie R Palmer, Andrew F Olshan
PURPOSE: Circulating anti-Müllerian hormone (AMH) levels are positively associated with time to menopause and breast cancer risk. We examined breast cancer associations with single nucleotide polymorphisms (SNPs) in the AMH gene or its receptor genes, ACVR1 and AMHR2, among African American women. METHODS: In the AMBER consortium, we tested 65 candidate SNPs, and 1130 total variants, in or near AMH, ACVR1, and AMHR2 and breast cancer risk. Overall, 3649 cases and 4230 controls contributed to analyses...
September 22, 2020: Breast Cancer Research and Treatment