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anti-Mullerian hormone

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https://www.readbyqxmd.com/read/28327456/relationship-between-plasma-anti-m%C3%A3-llerian-hormone-concentrations-during-the-rearing-period-and-subsequent-embryo-productivity-in-japanese-black-cattle
#1
H Nabenishi, G Kitahara, S Takagi, A Yamazaki, T Osawa
To use plasma anti-Müllerian hormone (AMH) concentrations as early-stage markers for donor cow selection, we investigated the relationship between plasma AMH concentrations in Japanese black heifers and subsequent embryo productivity following superovulation treatment. Plasma AMH and nonesterified fatty acid (NEFA) concentrations in 6 heifers were evaluated once per month from 3 mo before successful AI for primiparity to 3 mo postpartum. Following calving, embryo collection by superovulation treatment was performed at 3- to 4-mo intervals...
February 4, 2017: Domestic Animal Endocrinology
https://www.readbyqxmd.com/read/28324271/anti-mullerian-hormone-concentrations-in-individual-follicular-fluids-within-one-stimulated-ivf-cycle-resemble-blood-serum-values
#2
Michael Schenk, Julia Maria Kröpfl, Barbara Obermayer-Pietsch, Elisabeth Feldmeier, Gregor Weiss
PURPOSE: Anti-Mullerian hormone (AMH) is commonly known as the most potent marker for ovarian reserve due to its decline as female age increases. While serum AMH (sAMH) levels have been intensively investigated, there is less data regarding AMH concentrations in follicular fluid (FF), since FF has usually been designated as waste product during oocyte collection in assisted reproductive technologies. This pilot study investigated follicle AMH concentrations (fAMH) of several follicles per ovary, individually collected with the Steiner-Tan needle, and compared them to sAMH concentrations in women undergoing IVF treatment...
March 21, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28324034/anti-mullerian-hormone-and-ovarian-morphology-in-women-with-isolated-hypogonadotropic-hypogonadism-kallmann-syndrome-effects-of-recombinant-human-fsh
#3
Hélène Bry-Gauillard, Florence Larrat-Ledoux, Jean-Marc Levaillant, Nathalie Massin, Luigi Maione, Isabelle Beau, Nadine Binart, Philippe Chanson, Sylvie Brailly-Tabard, Janet E Hall, Jacques Young
Context: Isolated hypogonadotropic hypogonadism (IHH), characterized by gonadotropin deficiency and absent puberty, is very rare in women. IHH prevents pubertal ovarian stimulation, but anti-Mullerian hormone (AMH) and antral follicle count (AFC), have not been studied. Objectives: 1) Compare, in IHH versus controls, AMH, ovarian volume (OV) and AFC. 2) Compare in IHH, ovarian responses to recombinant human FSH (rhFSH) and rhFSH plus rhLH. Subjects: 68 IHH women, 51 matched healthy women...
January 27, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28319016/anti-m%C3%A3-llerian-hormone-kinetics-in-pregnancy-and-post-partum-a-systematic-review
#4
REVIEW
Sarah McCredie, William Ledger, Christos A Venetis
The aim of this systematic review is to critically appraise the available evidence regarding the kinetics of anti-Müllerian hormone (AMH) during pregnancy and post-partum. A systematic literature search was conducted in MEDLINE, Embase, CENTRAL, Scopus and Web of Science on 14 December 2015, aiming to identify studies providing data on the serum concentration of AMH in women at various stages of gestation and post-partum. There was a total of 1719 participants across eight studies. Seven out of the eight studies reported a decline in serum AMH concentration with advancing gestational age...
February 24, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28316072/the-effects-of-dash-diet-on-weight-loss-anti-m%C3%A3-llerian-hormone-and-metabolic-profiles-in-women-with-polycystic-ovary-syndrome-a-randomized-clinical-trial
#5
Fatemeh Foroozanfard, Hamideh Rafiei, Mansooreh Samimi, Hamid Reza Gilasi, Roohangiz Gorjizadeh, Zahra Heidar, Zatollah Asemi
OBJECTIVE: This study was designed to evaluate the effects of the Dietary Approaches to Stop Hypertension (DASH diet) on weight loss, anti-Müllerian hormone (AMH) and metabolic profiles in women with polycystic ovary syndrome (PCOS). DESIGN, PATIENTS AND MEASUREMENTS: A randomized controlled clinical trial was conducted among 60 overweight or obese patients with PCOS. Patients were randomly assigned to receive either low-calorie DASH (N=30) or control diet (N=30) for 12 weeks...
March 18, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/28302175/prolonged-hypothyroidism-severely-reduces-ovarian-follicular-reserve-in-adult-rats
#6
Li Meng, Eddy Rijntjes, Hans J M Swarts, Jaap Keijer, Katja J Teerds
BACKGROUND: There is substantial evidence both in humans and in animals that a prolonged reduction in plasma thyroid hormone concentration leads to reproductive problems, including disturbed folliculogenesis, impaired ovulation and fertilization rates, miscarriage and pregnancy complications. The objective of the present study is to examine the consequences of chronic hypothyroidism, induced in adulthood, for the size of the ovarian follicle pool. In order to investigate this, adult female rats were provided either a control or an iodide deficient diet in combination with perchlorate supplementation to inhibit iodide uptake by the thyroid...
March 16, 2017: Journal of Ovarian Research
https://www.readbyqxmd.com/read/28299573/mkrn3-levels-in-girls-with-central-precocious-puberty-and-correlation-with-sexual-hormone-levels-a-pilot-study
#7
Anna Grandone, Grazia Cirillo, Marcella Sasso, Carlo Capristo, Gianluca Tornese, Pierluigi Marzuillo, Caterina Luongo, Giuseppina Rosaria Umano, Adalgisa Festa, Ruggero Coppola, Emanuele Miraglia Del Giudice, Laura Perrone
PURPOSE: Recently, mutations of makorin RING-finger protein 3 (MKRN3) have been described in familial central precocious puberty. Serum levels of this protein decline before the pubertal onset in healthy girls and boys. The aim of the study is to investigate MKRN3 circulating levels in patients with central precocious puberty. METHODS: We performed an observational cross-sectional study. We enrolled 17 patients with central precocious puberty aged 7 years (range: 2-8 years) and breast development onset <8 years; 17 prepubertal control age-matched patients aged 6...
March 15, 2017: Endocrine
https://www.readbyqxmd.com/read/28293053/effect-of-melatonin-on-the-outcome-of-assisted-reproductive-technique-cycles-in-women-with-diminished-ovarian-reserve-a-double-blinded-randomized-clinical-trial
#8
Bahia Namavar Jahromi, Sara Sadeghi, Shohreh Alipour, Mohammad Ebrahim Parsanezhad, Shaghayegh Moradi Alamdarloo
Diminished ovarian reserve (DOR) significantly decreases the success rate of the assisted reproductive technique (ART). In this study, we assessed the effect of melatonin on the ART outcomes in women with DOR. A double-blinded, randomized, clinical trial was performed on 80 women with DOR as a pilot study in Shiraz, between 2014 and 2015. DOR was defined as the presence of 2 of the following 3 criteria: 1) anti-Müllerian hormone ≤1, 2) follicle-stimulating hormone ≥10, and 3) bilateral antral follicle count ≤6...
January 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28285954/anti-m%C3%A3-llerian-hormone-concentrations-and-parity-in-fertile-women-the-model-of-oocyte-donors
#9
Sophie Catteau-Jonard, Marie Roux, Agathe Dumont, Anne-Sophie Delesalle, Geoffroy Robin, Didier Dewailly
In France until the end of 2015, oocyte donors must have had at least one child and be aged 18-37 years. This population of fertile women was selected to examine whether serum anti-Müllerian hormone (AMH) concentration could be a reliable correlate of spontaneous pregnancy in women who had proven their fertility before. A cohort of 217 women followed between 2009 and 2015 for oocyte donation at the University Hospital of Lille comprised this retrospective study. In these egg donors, aged 20-37 (median: 32 years), the median serum AMH level was 22 pmol/l (5-95th percentiles: 4...
March 1, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28285952/ovarian-response-to-150%C3%A2-%C3%A2%C2%B5g-corifollitropin-alfa-in-a-gnrh-antagonist-multiple-dose-protocol-a-prospective-cohort-study
#10
Tamara Lerman, Marion Depenbusch, Askan Schultze-Mosgau, Soeren von Otte, Markus Scheinhardt, Inke Koenig, Axel Kamischke, Milan Macek, Arne Schwennicke, Sabine Segerer, Georg Griesinger
The incidence of low (<6 oocytes) and high (>18 oocytes) ovarian response to 150 µg corifollitropin alfa in relation to anti-Müllerian hormone (AMH) and other biomarkers was studied in a multi-centre (n = 5), multi-national, prospective, investigator-initiated, observational cohort study. Infertile women (n = 212), body weight >60 kg, underwent controlled ovarian stimulation in a gonadotrophin-releasing hormone-antagonist multiple-dose protocol. Demographic, sonographic and endocrine parameters were prospectively assessed on cycle day 2 or 3 of a spontaneous menstruation before the administration of 150 µg corifollitropin alfa...
March 2, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28279229/human-umbilical-cord-mesenchymal-stem-cells-improve-the-reserve-function-of-perimenopausal-ovary-via-a-paracrine-mechanism
#11
Jia Li, QiuXian Mao, JingJun He, HaoQing She, Zhi Zhang, ChunYan Yin
BACKGROUND: Human umbilical cord mesenchymal stem cells (hUCMSCs) are a type of pluripotent stem cell which are isolated from the umbilical cord of newborns. hUCMSCs have great therapeutic potential. We designed this experimental study in order to investigate whether the transplantation of hUCMSCs can improve the ovarian reserve function of perimenopausal rats and delay ovarian senescence. METHOD: We selected naturally aging rats confirmed by vaginal smears as models of perimenopausal rats, divided into the control group and the treatment group, and selected young fertile female rats as normal controls...
March 9, 2017: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/28277814/the-cutoff-values-of-serum-amh-levels-and-starting-recfsh-doses-for-the-individualization-of-ivf-treatment-strategies
#12
Pinar Özcan, Cem Fiçicioğlu, Seda Ateş, Meltem Güner Can, Çiğdem Kaspar, Oya Akçin, Mert Yesiladali
OBJECTIVE: The main purpose of our study is to categorize starting doses of recombinant follicle-stimulating hormone (recFSH) based on various cutoff values of anti-Mullerian hormone (AMH) and to determine the effectiveness of serum AMH levels in the prediction of poor ovarian response. MATERIAL AND METHODS: Prospective data analysis was conducted at IVF center. A total of 323 patients were included. All patients were divided into four groups according to the patients' serum AMH concentrations: Group 1 (AMH < 1 ng/ml; 450 IU/day n = 157); Group 2 (AMH 1-2 ng/ml; 375 IU/day, n = 55); Group 3 (AMH 2-3 ng/ml; 225 IU/day, n = 48); and Group 4 (AMH > 3 ng/ml; 150 IU/day, n = 63)...
March 9, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28276867/pathogenesis-and-treatment-of-adult-type-granulosa-cell-tumor-of-the-ovary
#13
Anniina Färkkilä, Ulla-Maija Haltia, Johanna Tapper, Melissa K McConechy, David G Huntsman, Markku Heikinheimo
Adult-type granulosa cell tumor is a clinically and molecularly unique subtype of ovarian cancer. These tumors originate from the sex cord stromal cells of the ovary and represent 3-5% of all ovarian cancers. The majority of adult-type granulosa cell tumors are diagnosed at an early stage with an indolent prognosis. Surgery is the cornerstone for the treatment of both primary and relapsed tumor, while chemotherapy is applied only for advanced or non-resectable cases. Tumor stage is the only factor consistently associated with prognosis...
March 6, 2017: Annals of Medicine
https://www.readbyqxmd.com/read/28270607/mtorc1-2-inhibition-preserves-ovarian-function-and-fertility-during-genotoxic-chemotherapy
#14
Kara N Goldman, Devon Chenette, Rezina Arju, Francesca E Duncan, David L Keefe, Jamie A Grifo, Robert J Schneider
The ovary contains oocytes within immature (primordial) follicles that are fixed in number at birth. Activation of follicles within this fixed pool causes an irreversible decline in reproductive capacity, known as the ovarian reserve, until menopause. Premenopausal women undergoing commonly used genotoxic (DNA-damaging) chemotherapy experience an accelerated loss of the ovarian reserve, leading to subfertility and infertility. Therefore, there is considerable interest but little effective progress in preserving ovarian function during chemotherapy...
March 7, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28253506/the-effect-of-the-testis-on-the-ovary-structure-function-relationships-in-a-neonate-with-a-unilateral-ovotestis-ovotesticular-disorder-of-sex-development-%C3%A2
#15
Siri Atma W Greeley, Elizabeth Littlejohn, Aliya N Husain, Darrel Waggoner, Mohan Gundeti, Robert L Rosenfield
AIMS: To evaluate gonadal function in a newborn with suspected ovotesticular disorder of sex development (DSD). METHODS: Gonadal function was evaluated at baseline and after gonadotropin-releasing hormone agonist (GnRHag) stimulation testing. RESULTS: A full-term 46,XX neonate with genital ambiguity produced serum testosterone and anti-Müllerian hormone (AMH) levels appropriate for males within days, while serum estradiol remained prepubertal, both spontaneously and in response to GnRHag stimulation testing...
March 2, 2017: Hormone Research in Pædiatrics
https://www.readbyqxmd.com/read/28245188/amh-levels-in-girls-with-various-pubertal-problems
#16
Senay Savas-Erdeve, Elif Sagsak, Meliksah Keskin, Semra Cetinkaya, Zehra Aycan
BACKGROUND: Anti-Müllerian hormone (AMH) is produced by granulosa cells surrounding follicles that have undergone recruitment from the primordial follicle pool but have not been selected for dominance (preantral and early antral follicles). In healthy girls, serum levels of AMH vary considerably between individuals. We aimed to evaluate the AMH level in girls with premature thelarche (PT) and central precocious puberty (CPP). METHODS: Girls with CPP (n=21), PT (n=24) and a control prepubertal group (n=22) were included in the study...
March 1, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/28240757/-anti-m%C3%A3-llerian-hormone-a-brief-review-of-the-literature
#17
G Ozzola
BACKGROUND: Anti-Müllerian hormone (AMH) is a dimeric glycoprotein, which was originally identified because of its role in male sexual differentiation. In fact, AMH is expressed by the Sertoli cellsof the foetal testes and induces the regression of the Müllerian ducts. In the absence of AMH, the Müllerian ducts evolve in the uterus, fallopian tubes and in the upper part of the vagina. In women AMH is produced by granulose cells, pre-antral and antral follicles and its major physiological role in the ovaries seems to be limited to inhibiting the development of the earliest stages of follicular development...
January 2017: La Clinica Terapeutica
https://www.readbyqxmd.com/read/28238309/-deep-infiltrative-endometriosis-without-digestive-involvement-what-is-the-impact-of-surgery-on-in-vitro-fertilization-outcomes-a-retrospective-study
#18
L Mounsambote, J Cohen, S Bendifallah, E Mathieu d'Argent, L Selleret, N Chabbert-Buffet, M Ballester, J M Antoine, E Daraï
OBJECTIVES: To evaluate the impact of complete removal of endometriosis in case of deep infiltrative endometriosis without digestive involvement, on in vitro fertilization outcomes. METHODS: Retrospective monocentric study. We included infertile women with deep infiltrative endometriosis without colorectal involvement that underwent IVF. Women were divided in two groups, following their history: "surgery" when they underwent complete endometriosis resection before IVF and "without surgery" when they underwent IVF without endometriosis removal...
January 2017: Gynecol Obstet Fertil Senol
https://www.readbyqxmd.com/read/28237349/repeatability-of-antral-follicle-counts-and-anti-m%C3%A3-llerian-hormone-and-their-associations-determined-at-an-unknown-stage-of-follicular-growth-and-an-expected-day-of-follicular-wave-emergence-in-dairy-cows
#19
M Gobikrushanth, P A Dutra, T C Bruinjé, M G Colazo, S T Butler, D J Ambrose
The objectives were to determine (1) the repeatability of antral follicle counts (AFC) and anti-Müllerian hormone (AMH) concentrations at an unknown stage of follicular growth (FG) and at an expected day of follicular wave emergence (FWE) in dairy cows, and (2) the association between AFC and AMH at the above two stages. Transrectal ultrasound imaging of the ovaries and blood sample collection were performed on 91 lactating Holstein cows (33 primiparous, 58 multiparous) to determine AFC and serum concentrations of AMH at an unknown stage of FG (mean ± SEM; 14 ± 0...
April 1, 2017: Theriogenology
https://www.readbyqxmd.com/read/28224431/clinical-value-of-serum-anti-mullerian-hormone-and-inhibin-b-in-prediction-of-ovarian-response-in-patients-with-polycystic-ovary-syndrome
#20
Fan Zhang, Xiao-Ling Liu, Nan Rong, Xiao-Wen Huang
The present study aimed to investigate the clinical value of serum anti-mullerian hormone (AMH) and inhibin B (INHB) in predicting the ovarian response of patients with polycystic ovary syndrome (PCOS). A total of 120 PCOS patients were enrolled and divided into three groups in terms of the ovarian response: a low-response group (n=36), a normal-response group (n=44), and a high-response group (n=40). The serum AMH and INHB levels were measured by enzyme-linked immunosorbent assay (ELISA). The follicle stimulating hormone (FSH), luteinizing hormone (LH), and estradiol (E2) levels were determined by chemiluminescence microparticle immunoassay...
February 2017: Journal of Huazhong University of Science and Technology. Medical Sciences
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