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https://www.readbyqxmd.com/read/29028148/follow-up-of-1887-patients-receiving-tumor-necrosis-alpha-antagonists-tuberculin-skin-test-conversion-and-tuberculosis-risk
#1
Tulin Cagatay, Zuleyha Bingol, Esen Kıyan, Zeynep Yegin, Gulfer Okumus, Orhan Arseven, Feyza Erkan, Ziya Gulbaran, Mustafa Erelel, Turhan Ece, Penbe Cagatay', Zeki Kılıçaslan
OBJECTIVES: To evaluate the characteristics of patients who developed tuberculosis while receiving tumor necrosis factor-alpha (TNF-α) antagonists and the related factors with tuberculosis. METHODS: Patient's demographics, tuberculin skin test (TST), isoniazid prophylaxis, type of TNF-α antagonist were recorded. TST conversion (>5mm increase) was evaluated for patients who had baseline and 1-year TST. RESULTS: Files of 1887 patients who were receiving TNF-α antagonists between August2005 and June 2015 were evaluated...
October 13, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29027192/hip-resurfacing-arthroplasty-for-patients-with-inflammatory-arthritis-a-systematic-review
#2
Kyle W Morse, Edwin P Su
INTRODUCTION: Modern metal-on-metal hip resurfacing arthroplasty has led to decreased revision rates and high implant survival rates as compared to prior generations of resurfacing. Many of the series that report on resurfacing outcomes focus upon patients treated with a diagnosis of osteoarthritis. Patients with inflammatory arthritis such as rheumatoid arthritis (RA) and ankylosing spondylitis (AS) are also treated in these series, however, their outcomes following resurfacing are underreported...
October 12, 2017: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/29026327/characterization-and-prevalence-of-spondyloarthritis-and-peripheral-arthritis-among-patients-with-inflammatory-bowel-disease
#3
Hoda M Malaty, Grace Hsiao-Wei Lo, Jason K Hou
BACKGROUND: Joint complaints such as spondyloarthritis and peripheral arthritis are the most common extraintestinal manifestations in patients with inflammatory bowel disease (IBD); however, the evaluation of these symptoms are poorly described. OBJECTIVES: To examine the clinical characteristics and prevalence of ankylosing spondylitis (AS) and other joint complaints among patients with IBD. METHODS: In a local cohort of patients diagnosed with IBD between 1996 and 2009, we performed a retrospective study at the Veterans Affairs Hospital...
2017: Clinical and Experimental Gastroenterology
https://www.readbyqxmd.com/read/29021885/fracture-dislocation-at-c6-c7-level-with-quadriplegia-after-traditional-massage-in-a-patient-with-ankylosing-spondylitis-a-case-report
#4
Kak Abilash, Qmq Mohd, Zah Ahmad, Basir Towil
Ankylosing spinal disorders (ASD) tend to result in fractures and/or dislocations after minor trauma because of the altered biomechanical properties. The relative risk of traumatic vertebral fractures in patients with ankylosing spondylitis has been estimated as three times higher than in the general population. These spine traumas, which are located at cervical level in 81% of patients with ankylosing spondylitis, are complicated by neurological lesions in 65% of patients, due to the high inherent instability of these fractures...
July 2017: Malaysian Orthopaedic Journal
https://www.readbyqxmd.com/read/29020487/clinical-characteristics-and-prognostic-factors-in-ankylosing-spondylitis-associated-uveitis
#5
Ji Hwan Lee, Moonjung Choi, Tyler Hyung Taek Rim, Sung Chul Lee, Christopher Seungkyu Lee
PURPOSE: To identify the clinical features and prognostic factors of uveitis associated with ankylosing spondylitis (AS). METHODS: This retrospective, interventional case series study reviewed the medical records of 91 AS patients with uveitis. RESULTS: The characteristics of AS-associated uveitis included male preponderance (70%), average onset in the fourth decade, unilateral manifestation (87.9%), and vitreous involvement or retinal vascular leakage (36...
October 11, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/29019640/spine-conditions-mechanical-and-inflammatory-low-back-pain
#6
Christopher Ledford
Mechanical low back pain (LBP) is an injury or derangement of an anatomic structure in the low back. When evaluating patients with LBP, clinicians should maintain clinical suspicion for vertebral fracture, cancer, and cauda equina syndrome. Management includes patient education focused on exercise, massage, and behavioral approaches such as cognitive behavioral therapy. Acupuncture can be an effective alternative and specific herbal supplements may provide short-term pain relief. The prognosis for patients with mechanical LBP is good...
October 2017: FP Essentials
https://www.readbyqxmd.com/read/29016762/diagnosis-of-tooth-ankylosis-using-panoramic-views-cone-beam-computed-tomography-and-histological-data-a-retrospective-observational-case-series-study
#7
Franziska Ducommun, Michael M Bornstein, Dieter Bosshardt, Christos Katsaros, Karl Dula
Objectives: The aim of this study was to determine whether cone beam computed tomography is a reliable radiological method to diagnose tooth ankylosis. Materials and methods: A series of teeth clinically diagnosed as ankylosed were collected after extraction in a private practice from 2009 to 2015 and analyzed retrospectively. Inclusion criteria comprised permanent molars extracted due to failed tooth eruption in the absence of any visible mechanical obstruction, existing panoramic view (PV), and cone beam computed tomography (CBCT) and histological sections of sufficient quality...
August 22, 2017: European Journal of Orthodontics
https://www.readbyqxmd.com/read/28990333/a-truly-complementary-approach-a-qualitative-exploration-of-complementary-and-alternative-medicine-practitioners-views-of-treating-ankylosing-spondylitis
#8
Hannah Family, Abbie Jordan, Kelly Blaxall, Raj Sengupta
OBJECTIVE: Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease in which individuals experience a long delay to diagnosis. Prior to diagnosis, individuals report frequent use of complementary and alternative medicine (CAM) therapies. While popularly used, there is a dearth of knowledge concerning the experiences of CAM practitioners in terms of treating individuals with AS. Addressing this knowledge gap, the present study provides a detailed exploration of how UK-based CAM practitioners treat individuals with AS...
October 9, 2017: Musculoskeletal Care
https://www.readbyqxmd.com/read/28985620/serum-levels-of-leptin-adiponectin-and-resistin-in-patients-with-ankylosing-spondylitis-a-systematic-review-and-meta-analysis
#9
REVIEW
Jiajia Yang, Xu Zhang, Yubo Ma, Meng Wu, Xingxing Hu, Renfang Han, Yaping Yuan, Mengmeng Wang, Mengya Chen, Shanqun Jiang, Jingjing Tong, Shengqian Xu, Jianhua Xu, Zongwen Shuai, Yanfeng Zou, Faming Pan
OBJECTIVES: Various studies have researched the serum levels of leptin, adiponectin and resistin in patients with ankylosing spondylitis (AS), but the results were inconclusive. The purpose of this study was to systematically evaluate the correlations between serum levels of these adipokines and AS. METHODS: Electronic databases were retrieved to search relevant publications. Pooled standard mean difference (SMD) with 95% confidence interval (CI) was calculated by the random-effect model...
October 3, 2017: International Immunopharmacology
https://www.readbyqxmd.com/read/28984512/spinal-cord-injury-after-traumatic-spine-fracture-in-patients-with-ankylosing-spinal-disorders
#10
Frederik R Teunissen, Bianca M Verbeek, Thomas D Cha, Joseph H Schwab
OBJECTIVE Spinal cord injury (SCI) is a major complication of spinal fractures in patients with ankylosing spondylitis (AS) and diffuse idiopathic skeletal hyperostosis (DISH). Due to the uncommon nature of these conditions, existing literature consists of relatively small case series without detailed neurological data. This study aims to investigate the incidence, predictors, and sequelae of SCI in patients with a traumatic fracture of the ankylosed spine. METHODS The study included all patients older than 18 years of age with AS or DISH who presented to two affiliated tertiary care centers between January 1, 1990, and January 1, 2016, and had a traumatic fracture of the spine...
October 6, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28983663/the-role-of-land-and-aquatic-exercise-in-ankylosing-spondylitis-a-systematic-review
#11
REVIEW
Ana Zão, Pedro Cantista
Ankylosing spondylitis (AS) is a chronic and inflammatory rheumatic disease, characterized by pain and structural and functional impairments, such as reduced mobility and axial deformity, which lead to diminished quality of life. Its treatment includes not only drugs, but also nonpharmacological therapy. Exercise appears to be a promising modality. The aim of this study is to review the current evidence and evaluate the role of exercise either on land or in water for the management of patients with AS in the biological era...
October 5, 2017: Rheumatology International
https://www.readbyqxmd.com/read/28982344/retraction-ankylosing-spondylitis-among-familial-mediterranean-fever-patients
#12
(no author information available yet)
This paper is under revision and has not been accepted yet.
October 3, 2017: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/28980904/optimal-concentration-range-of-golimumab-in-patients-with-axial-spondyloarthritis
#13
Ana Martínez-Feito, Chamaida Plasencia-Rodriguez, Victoria Navarro-Compán, Teresa Jurado, Eva Linda Kneepkens, Gertjan J Wolbink, Sergio Martín, Ainhoa Ruiz Del Agua, Rosaura Navarro, Araceli Mezcua, Andrea Jochems, Diana Peiteado, Maria Gema Bonilla, Alejandro Balsa, Dora Pascual-Salcedo
OBJECTIVES: To investigate the association between serum golimumab (GLM) trough levels, clinical disease activity and treatment response during the first year of therapy in patients with axial spondyloarthritis (axSpA), as well as determining an optimal concentration range of GLM in axSpA. METHODS: This was an observational prospective study including 49 patients with axSpA monitored during 52 weeks (W52). Serum GLM trough levels were measured by capture ELISA and antidrug antibodies by bridging ELISA at baseline, W24 and W52...
September 15, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28977661/managing-morbidity-and-treatment-related-toxicity-in-patients-with-ankylosing-spondylitis
#14
Martin Bergman, Amy Lundholm
AS is the prototypical member of the family of spondyloarthropathies, and is characterized by seronegativity, axial predominance and new bone formation, which underlie symptoms of inflammatory back pain, enthesopathy and extra-articular manifestations, including anterior uveitis, psoriasis and colitis. Patients with AS typically experience a wide variety of morbidities. These include both morbidities related to the disease itself-most prominently progressive, irreversible, structural damage to the axial or peripheral skeleton-and morbidities stemming from treatments for the disease, including toxicities from NSAID use, and increased risk of infections and immunogenicity concerns with biologics...
August 4, 2017: Rheumatology
https://www.readbyqxmd.com/read/28971528/m2-polarization-of-monocytes-in-ankylosing-spondylitis-and-relationship-with-inflammation-and-structural-damage
#15
Jinzhu Zhao, Wei Yuan, Chunsheng Tao, Peifeng Sun, Zaixing Yang, Weidong Xu
The aim of this study was to evaluate the polarization of peripheral blood monocytes in the patients with ankylosing spondylitis (AS) and to determine the correlations between monocyte polarization and inflammation and structural damage. A total of 120 AS patients, 50 rheumatoid arthritis (RA) patients and 100 healthy controls were enrolled in the study. M1 (CD68+CD192+) and M2 (CX3CR1+CD163+) monocytes were characterized by flow cytometry. Demographic, clinical, radiographic and laboratory data were collected and analyzed...
October 3, 2017: APMIS: Acta Pathologica, Microbiologica, et Immunologica Scandinavica
https://www.readbyqxmd.com/read/28970729/patients-with-inflammatory-bowel-disease-have-increased-risk-of-autoimmune-and-inflammatory-diseases
#16
Morten L Halling, Jens Kjeldsen, Torben Knudsen, Jan Nielsen, Lars Koch Hansen
AIM: To investigate whether immune mediated diseases (IMD) are more frequent in patients with inflammatory bowel disease (IBD). METHODS: In this population based registry study, a total of 47325 patients with IBD were alive and registered in the Danish National Patient Registry on December 16, 2013. Controls were randomly selected from the Danish Civil Registration System (CRS) and matched for sex, age, and municipality. We used ICD 10 codes to identify the diagnoses of the included patients...
September 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28970076/temporomandibular-joint%C3%A2-involvement-in-ankylosing-spondylitis
#17
Faten Frikha, Mouna Snoussi, Sondes Briki, Fathi Karray, Zouhir Bahloul
No abstract text is available yet for this article.
September 29, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28969061/rs2841277-pld4-is-associated-with-susceptibility-and-rs4672495-is-associated-with-disease-activity-in-rheumatoid-arthritis
#18
Wei-Chiao Chen, Wen-Chang Wang, Yukinori Okada, Wei-Pin Chang, Yii-Her Chou, Hui-Hua Chang, Jin-Ding Huang, Der-Yuan Chen, Wei-Chiao Chang
Rheumatoid arthritis (RA) is one of the most common autoimmune diseases, can lead to long-term joint damage, chronic pain, and loss of motor function in the hands, and may share some common genetic factors with other autoimmune disorders, such as ankylosing spondylitis (AS). Many single-nucleotide polymorphisms (SNPs) were reported by genome-wide association studies (GWASs) of RA, but some of them have not been examined in the Taiwanese population. In this study, for 15 SNPs reported in previous RA and AS GWASs, we investigated their association with RA in a Taiwanese population...
September 8, 2017: Oncotarget
https://www.readbyqxmd.com/read/28968836/limited-reliability-of-radiographic-assessment-of-spinal-progression-in-ankylosing-spondylitis
#19
Sibel Zehra Aydin, Esen Kasapoglu Gunal, Esra Kurum, Servet Akar, Halit Eyyup Mungan, Fatma Alibaz-Oner, Robert G Lambert, Pamir Atagunduz, Helena Marzo Ortega, Dennis McGonagle, Walter P Maksymowych
Objectives: Conventional radiography is key to assessing AS-related spinal involvement and has become increasingly important given that spinal fusion may continue under biologic therapy. We aimed to compare the reliability of radiographic scoring of the spine by using different approaches to understand how different readers agree on overall scores and on individual findings. Method: Six investigators scored 68 plain radiographs of the cervical and lumbar spine of 34 patients with a 2-year interval, for erosions, sclerosis, squaring, syndesmophytes and ankyloses using the Spondyloarthritis Radiography (SPAR) module...
September 15, 2017: Rheumatology
https://www.readbyqxmd.com/read/28967358/causes-of-pain-in-patients-with-axial-spondyloarthritis
#20
REVIEW
Uta Kiltz, Xenofon Baraliakos, Andrea Regel, Bjoern Bühring, Juergen Braun
Back pain, most frequently of the inflammatory type, is the leading symptom in patients with axial spondyloarthritis (axSpA). Back pain in these patients is usually either due to axial inflammation or structural changes based on new bone formation. However, there are other possible causes of pain in these patients. There is, for example, a strongly increased risk of vertebral fractures, and, especially in patients with longstanding disease, degenerative spinal changes may play an additional role as a cause of pain...
September 2017: Clinical and Experimental Rheumatology
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