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https://www.readbyqxmd.com/read/28738601/biosensor-assisted-selection-of-optimal-parameters-for-designing-molecularly-imprinted-polymers-selective-to-phosmet-insecticide
#1
Nadin Aftim, Georges Istamboulié, Elena Piletska, Sergey Piletsky, Carole Calas-Blanchard, Thierry Noguer
Molecularly imprinted polymers (MIPs) for phosmet insecticide were synthesized by batch polymerization. The affinity of functional monomers to phosmet was tested using an original method involving an electrochemical biosensor based on acetylcholinesterase inhibition. It was demonstrated that association of phosmet with appropriate functional monomers resulted in a decrease of enzyme inhibition. Using this method, it was shown that N,N-methylenebis(acrylamide) displayed the highest interactions with phosmet using DMSO as solvent...
November 1, 2017: Talanta
https://www.readbyqxmd.com/read/28738408/cgas-surveillance-of-micronuclei-links-genome-instability-to-innate-immunity
#2
Karen J Mackenzie, Paula Carroll, Carol-Anne Martin, Olga Murina, Adeline Fluteau, Daniel J Simpson, Nelly Olova, Hannah Sutcliffe, Jacqueline K Rainger, Andrea Leitch, Ruby T Osborn, Ann P Wheeler, Marcin Nowotny, Nick Gilbert, Tamir Chandra, Martin A M Reijns, Andrew P Jackson
DNA is strictly compartmentalized within the nucleus to prevent autoimmunity; despite this, cyclic GMP-AMP synthase (cGAS), a cytosolic sensor of double-stranded DNA, is activated in autoinflammatory disorders and by DNA damage. Precisely how cellular DNA gains access to the cytoplasm remains to be determined. Here, we report that cGAS localizes to micronuclei arising from genome instability in a mouse model of monogenic autoinflammation, after exogenous DNA damage and spontaneously in human cancer cells. Such micronuclei occur after mis-segregation of DNA during cell division and consist of chromatin surrounded by its own nuclear membrane...
July 24, 2017: Nature
https://www.readbyqxmd.com/read/28738203/early-detection-monitoring-for-aquatic-non-indigenous-species-optimizing-surveillance-incorporating-advanced-technologies-and%C3%A2-identifying-research-needs
#3
REVIEW
Anett S Trebitz, Joel C Hoffman, John A Darling, Erik M Pilgrim, John R Kelly, Emily A Brown, W Lindsay Chadderton, Scott P Egan, Erin K Grey, Syed A Hashsham, Katy E Klymus, Andrew R Mahon, Jeffrey L Ram, Martin T Schultz, Carol A Stepien, James C Schardt
Following decades of ecologic and economic impacts from a growing list of nonindigenous and invasive species, government and management entities are committing to systematic early- detection monitoring (EDM). This has reinvigorated investment in the science underpinning such monitoring, as well as the need to convey that science in practical terms to those tasked with EDM implementation. Using the context of nonindigenous species in the North American Great Lakes, this article summarizes the current scientific tools and knowledge - including limitations, research needs, and likely future developments - relevant to various aspects of planning and conducting comprehensive EDM...
July 21, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28738098/somatization-disorder-and-somatoform-symptoms-in-systematically-studied-survivors-of-10-disasters
#4
Gus Zhang, Carol S North
BACKGROUND: There is little agreement about the association of somatization with exposure to disaster trauma in the existing literature. METHODS: Pre-disaster and post-disaster psychiatric disorders, somatization disorder, and individual somatoform (medically unexplained) symptoms were assessed with structured diagnostic interviews in 811 directly exposed survivors of 10 disasters. RESULTS: Only 1 individual met criteria for post-disaster somatization disorder; there were no incident cases...
August 1, 2017: Annals of Clinical Psychiatry: Official Journal of the American Academy of Clinical Psychiatrists
https://www.readbyqxmd.com/read/28738090/maternal-25-oh-d-concentrations-%C3%A2-40-ng-ml-associated-with-60-lower-preterm-birth-risk-among-general-obstetrical-patients-at-an-urban-medical-center
#5
Sharon L McDonnell, Keith A Baggerly, Carole A Baggerly, Jennifer L Aliano, Christine B French, Leo L Baggerly, Myla D Ebeling, Charles S Rittenberg, Christopher G Goodier, Julio F Mateus Niño, Rebecca J Wineland, Roger B Newman, Bruce W Hollis, Carol L Wagner
BACKGROUND: Given the high rate of preterm birth (PTB) nationwide and data from RCTs demonstrating risk reduction with vitamin D supplementation, the Medical University of South Carolina (MUSC) implemented a new standard of care for pregnant women to receive vitamin D testing and supplementation. OBJECTIVES: To determine if the reported inverse relationship between maternal 25(OH)D and PTB risk could be replicated at MUSC, an urban medical center treating a large, diverse population...
2017: PloS One
https://www.readbyqxmd.com/read/28738041/catheter-associated-urinary-tract-infections-implementing-a-protocol-to-decrease-incidence-in-oncology-populations%C3%A2
#6
Charis McCoy, Monica Paredes, Sara Allen, Jennifer Blackey, Carol Nielsen, Amy Paluzzi, Brittney Jonas, Patti Radovich
BACKGROUND: The impact of catheter-associated urinary tract infections (CAUTIs) on immunocompromised patients with cancer requires preventive intervention from bedside nurses.
. OBJECTIVES: This protocol aims to prevent CAUTIs in the inpatient oncology population by implementing an evidence-based, nurse-driven protocol for discontinuing indwelling urinary catheters (IUCs).
. METHODS: Following a literature review of 34 articles, a nurse-driven CAUTI prevention protocol was developed and implemented on two 26-bed oncology units...
August 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28738039/chemotherapy-extravasation-establishing-a-national-benchmark-for-incidence-among-cancer-centers
#7
Jeannette Jackson-Rose, Judith Del Monte, Adrienne Groman, Linda S Dial, Leah Atwell, Judy Graham, Rosemary O'Neil Semler, Maryellen O'Sullivan, Lisa Truini-Pittman, Terri A Cunningham, Lisa Roman-Fischetti, Eileen Costantinou, Chris Rimkus, Adrienne J Banavage, Barbara Dietz, Carol J Colussi, Kimberly Catania, Michelle Wasko, Kevin A Schreffler, Colleen West, Mary Lou Siefert, Robert David Rice
BACKGROUND: Given the high-risk nature and nurse sensitivity of chemotherapy infusion and extravasation prevention, as well as the absence of an industry benchmark, a group of nurses studied oncology-specific nursing-sensitive indicators. 
. OBJECTIVES: The purpose was to establish a benchmark for the incidence of chemotherapy extravasation with vesicants, irritants, and irritants with vesicant potential.
. METHODS: Infusions with actual or suspected extravasations of vesicant and irritant chemotherapies were evaluated...
August 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28737632/transgender-individuals-and-osteoporosis-prevention
#8
Carol A Sedlak, Cyndi Gale Roller, Manfred van Dulmen, Homood A Alharbi, Jessica D Sanata, Marci A Leifson, Amy J Veney, Hossam Alhawatmeh, Margaret OʼBryan Doheny
BACKGROUND: Risk behaviors and hormone use place transgender individuals (TIs) in jeopardy for osteoporosis. PURPOSE: The purpose of this study was to expand the science about the knowledge, health beliefs, and osteoporosis (OP) preventing behaviors of TIs. METHODS: This was a mixed-methods pilot study of a convenience sample of 31 TIs 30 years and older. Participants completed an online Osteoporosis Bone Health Survey. Fifteen participants were randomly selected for an interview to describe their perceptions of bone health...
July 2017: Orthopaedic Nursing
https://www.readbyqxmd.com/read/28736942/glycaemic-control-and-hypoglycaemia-in-people-with-type-2-diabetes-switching-from-twice-daily-basal-insulin-to-once-daily-insulin-glargine-300-u-ml-or-insulin-glargine-100-u-ml-edition-1-and-edition-2-subgroup-analysis
#9
Ronan Roussel, Michael C d'Emden, Miles Fisher, Francisco Javier Ampudia-Blasco, Peter Stella, Florence Bizet, Anna M G Cali, Carol H Wysham
This post hoc analysis compared glycaemic control and hypoglycaemia between insulin glargine 300 U/mL (Gla-300) and glargine 100 U/mL (Gla-100) administered once daily (QD) in people with T2DM from the EDITION 1 (basal plus mealtime insulin) and EDITION 2 (basal insulin plus oral antihyperglycaemic drugs) trials previously receiving twice-daily (BID) insulin. At randomisation, 16.9% and 20.0% of people in EDITION 1 and 2, respectively, were receiving BID basal insulin. HbA1c change from baseline to month 6 was comparable over 6 months with Gla-300 or Gla-100 (LS mean difference -0...
July 24, 2017: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/28736828/genomic-and-metabolic-characterization-of-a-chromophobe-renal-cell-carcinoma-cell-line-model-uok276
#10
Youfeng Yang, Cathy D Vocke, Christopher J Ricketts, Darmood Wei, Hesed M Padilla-Nash, Martin Lang, Carole Sourbier, J Keith Killian, Shawna L Boyle, Robert Worrell, Paul S Meltzer, Thomas Ried, Maria J Merino, Adam R Metwalli, W Marston Linehan
Chromophobe renal cell carcinoma (ChRCC) represents 5% of all RCC cases and frequently demonstrates multiple chromosomal losses and an indolent pattern of local growth, but can demonstrate aggressive features and resistance to treatment in a metastatic setting. Cell line models are an important tool for the investigation of tumor biology and therapeutic drug efficacy. Currently, there are few ChRCC-derived cell lines and none is well characterized. This study characterizes a novel ChRCC-derived cell line model, UOK276...
June 9, 2017: Genes, Chromosomes & Cancer
https://www.readbyqxmd.com/read/28736408/a-culture-of-understanding-reflections-and-suggestions-from-a-genomics-research-community-board
#11
Benjamin Kaplan, Carolyn Caddle-Steele, Gregory Chisholm, Warria A Esmond, Kadija Ferryman, Melvin Gertner, Crispin Goytia, Diane Hauser, Lynne D Richardson, Mimsie Robinson, Carol R Horowitz
There has been limited community engagement in the burgeoning field of genomics research. In the wake of a new discovery of genetic variants that increase the risk of kidney failure and are almost unique to people of African ancestry, community and clinical leaders in Harlem, New York, formed a community board to inform the direction of related research. The board advised all aspects of a study to assess the impact of testing for these genetic variants at primary care sites that serve diverse populations, including explaining genetic risk to participants...
2017: Progress in Community Health Partnerships: Research, Education, and Action
https://www.readbyqxmd.com/read/28736406/using-policy-briefs-to-present-scientific-results-of-cbpr-farmworkers-in-north-carolina
#12
Thomas A Arcury, Melinda F Wiggins, Carol Brooke, Anna Jensen, Phillip Summers, Dana C Mora, Sara A Quandt
BACKGROUND: Using scientific results to inform policy that improves health and well-being of vulnerable community members is essential to community-based participatory research (CBPR). OBJECTIVES: We describe "policy briefs," a mechanism developed to apply the results of CBPR projects with migrant and seasonal farmworkers to policy changes. LESSONS LEARNED: Policy briefs are two-page summaries of published research that address a single policy issue using language and graphics to make the science accessible to diverse audiences...
2017: Progress in Community Health Partnerships: Research, Education, and Action
https://www.readbyqxmd.com/read/28735919/sleep-disturbances-at-the-time-of-a-new-diagnosis-a-comparative-study-of-human-immunodeficiency-virus-patients-cancer-patients-and-general-population-controls
#13
Yen-Chin Chen, Cheng-Yu Lin, Carol Strong, Chung-Yi Li, Jeen-Shing Wang, Wen-Chien Ko, Nai-Ying Ko
OBJECTIVES: Sleep disturbances are a prevalent and troubling symptom of patients with highly stressful illnesses, such as human immunodeficiency virus (HIV) and cancer. The aim of this study was to compare the prevalence and incidence of sleep disturbances among persons with HIV, those with cancer, and the general population of Taiwan. METHODS: A matched cohort study design was used to compare the risk of sleep disturbances among three groups using reimbursement claims recorded in Taiwan's National Health Insurance Research Database (NHIRD)...
August 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28735582/health-literacy-and-fruit-and-vegetable-intake-in-rural-australia
#14
Siew Lim, Alison Beauchamp, Sarity Dodson, Jonathan O'Hara, Crystal McPhee, Alexandra Fulton, Carol Wildey, Richard H Osborne
OBJECTIVE: Adequate fruit and vegetable intake is important in the prevention of chronic disease. Health literacy is associated with health outcomes but its role in dietary behaviour has received little attention. The present study investigated the association between a multidimensional measure of health literacy, sociodemographic characteristics, and fruit and vegetable intake in rural Australia. DESIGN: A cross-sectional survey on intake of fruits and vegetables (servings/d), demographic characteristics and health literacy profile using a nine-scale Health Literacy Questionnaire (HLQ)...
July 24, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28735496/low-level-prenatal-toxin-exposures-and-breastfeeding-duration-a-prospective-cohort-study
#15
Casey B Rosen-Carole, Peggy Auinger, Cynthia R Howard, Elizabeth A Brownell, Bruce P Lanphear
Introduction Maternal exposure to tobacco smoke is associated with shortened breastfeeding duration, but few studies have examined the effects on breastfeeding outcomes of low level exposures to other toxic chemicals. Moreover, it is unclear if passive smoking is associated with duration of breastfeeding. Our objective was therefore to examine the effect of low-level prenatal exposures to common environmental toxins (tobacco smoke, lead, and phthalates) on breastfeeding exclusivity and duration. Methods We conducted an analysis of data from the Health Outcomes and Measures of the Environment (HOME) Study...
July 22, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/28735178/development-of-a-real-time-prediction-model-of-driver-behavior-at-intersections-using-kinematic-time-series-data
#16
Yaoyuan V Tan, Michael R Elliott, Carol A C Flannagan
As connected autonomous vehicles (CAVs) enter the fleet, there will be a long period when these vehicles will have to interact with human drivers. One of the challenges for CAVs is that human drivers do not communicate their decisions well. Fortunately, the kinematic behavior of a human-driven vehicle may be a good predictor of driver intent within a short time frame. We analyzed the kinematic time series data (e.g., speed) for a set of drivers making left turns at intersections to predict whether the driver would stop before executing the turn...
July 20, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28734485/the-power-of-nursing-an-innovative-course-in-values-clarification-and-self-discovery
#17
Lisa Day, Scott R Ziehm, Martha A Jessup, Pattie Amedro, Carol Dawson-Rose, Anne Derouin, Betsy Babb Kennedy, Sally Manahan, Abby Luck Parish, Rachel Naomi Remen
Teaching for a practice is more than the dissemination of knowledge and information to the learner. Professional nursing education requires teachers to facilitate students' self-reflection and awareness and assimilation of core professional and personal values in order for the new nurse to anchor and internalize these values as part of a professional identity. To achieve this, nursing educators recognize the importance of learning opportunities centered in the affective domain and the importance of teaching for professional formation that supports nursing students' commitment to the values of their chosen community of practice...
July 2017: Journal of Professional Nursing: Official Journal of the American Association of Colleges of Nursing
https://www.readbyqxmd.com/read/28734399/role-of-fluorodeoxyglucose-positron-emission-tomography-computed-tomography-in-the-evaluation-of-suspicious-pulmonary-nodules
#18
Brett W Carter, John P Lichtenberger, Girish S Shroff, Mylene T Truong, Carol C Wu
No abstract text is available yet for this article.
July 2017: Seminars in Roentgenology
https://www.readbyqxmd.com/read/28734397/incidental-findings-in-lung-cancer-screening-which-ones-are-relevant
#19
Myrna C B Godoy, Helena A C Pereira, Brett W Carter, Carol C Wu, Jeremy J Erasmus
No abstract text is available yet for this article.
July 2017: Seminars in Roentgenology
https://www.readbyqxmd.com/read/28734395/lung-computed-tomography-screening-reporting-and-data-system-version-1-0
#20
Brett W Carter, John P Lichtenberger, Girish S Shroff, Carol C Wu
No abstract text is available yet for this article.
July 2017: Seminars in Roentgenology
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