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https://www.readbyqxmd.com/read/27914355/characterisation-of-fine-grained-tailings-from-a-marble-processing-plant-and-their-acute-effects-on-the-copepod-calanus-finmarchicus
#1
Julia Farkas, Dag Altin, Karen M Hammer, Kaja C Hellstrøm, Andy M Booth, Bjørn Henrik Hansen
Submarine tailing disposal (STD) of mining waste is practiced as an alternative to land fill disposal in several countries. Knowledge regarding the environmental implications of STD on fjord and other marine ecosystems, including the pelagic environment, is scarce. In this study, we characterised the particle shape, size and metal content of the fine-grained fraction of tailings (FGT) from a Norwegian marble processing plant and investigated their acute toxicity and impact on feeding rate in adult Calanus finmarchicus...
November 30, 2016: Chemosphere
https://www.readbyqxmd.com/read/27913941/the-enigma-of-value-in-search-of-affordable-and-accessible-health-care
#2
EDITORIAL
Thomas D Szucs, Martina Weiss, Guido Klaus
In times of shrinking resources and pharmaceutical breakthrough situations, our value-assessing systems are stretched to their very limits. Assessing value is highly complex. Current value-assessment systems risk neglecting important factors, such as therapy duration, budget impact, or the importance of combination therapies. Especially when dealing with breakthrough therapies within high-prevalence indications, these factors play an important role in health care spending. When it comes to assessing value in Switzerland, the system is innovation and access-friendly; the price level of pharmaceutical products, however, is relatively high in comparison to neighboring countries...
December 2, 2016: European Journal of Health Economics: HEPAC: Health Economics in Prevention and Care
https://www.readbyqxmd.com/read/27909261/measuring-nutrition-governance-an-analysis-of-commitment-capability-and-collaboration-in-nepal
#3
Patrick Webb, Shibani Ghosh, Robin Shrestha, Grace Namirembe, Sabi Gurung, Diplav Sapkota, Winnie Fay Bell, Dale Davis, Eileen Kennedy, Shailes Neupane, Swetha Manohar, Kedar Baral
BACKGROUND: Global commitments to nutrition have supported calls for better evidence to support effective investments at national level. However, too little attention has so far been paid to the role of governance in achieving impacts. OBJECTIVE: This article explores the ways by which the commitment and capabilities of policy implementers affect collaborative efforts for achieving nutrition goals. METHODS: Over 1370 structured interviews were held with government and nongovernment officials over 3 years in 21 districts...
December 2016: Food and Nutrition Bulletin
https://www.readbyqxmd.com/read/27908286/cost-analysis-of-large-scale-implementation-of-the-helping-babies-breathe-newborn-resuscitation-training-program-in-tanzania
#4
Sumona Chaudhury, Lauren Arlington, Shelby Brenan, Allan Kaijunga Kairuki, Amunga Robson Meda, Kahabi G Isangula, Victor Mponzi, Dunstan Bishanga, Erica Thomas, Georgina Msemo, Mary Azayo, Alice Molinier, Brett D Nelson
BACKGROUND: Helping Babies Breathe (HBB) has become the gold standard globally for training birth-attendants in neonatal resuscitation in low-resource settings in efforts to reduce early newborn asphyxia and mortality. The purpose of this study was to do a first-ever activity-based cost-analysis of at-scale HBB program implementation and initial follow-up in a large region of Tanzania and evaluate costs of national scale-up as one component of a multi-method external evaluation of the implementation of HBB at scale in Tanzania...
December 1, 2016: BMC Health Services Research
https://www.readbyqxmd.com/read/27907130/environmental-nitrogen-losses-from-commercial-crop-production-systems-in-the-suwannee-river-basin-of-florida
#5
Rishi Prasad, George J Hochmuth
The springs and the Suwannee river of northern Florida in Middle Suwanee River Basin (MSRB) are among several examples in this planet that have shown a temporal trend of increasing nitrate concentration primarily due to the impacts of non-point sources such as agriculture. The rate of nitrate increase in the river as documented by Ham and Hatzell (1996) was 0.02 mg N L-1 y-1. Best management practices (BMPs) for nutrients were adopted by the commercial farms in the MSRB region to reduce the amounts of pollutants entering the water bodies, however the effectiveness of BMPs remains a topic of interest and discussion among the researchers, environmental administrators and policy makers about the loads of nitrogen entering into groundwater and river systems...
2016: PloS One
https://www.readbyqxmd.com/read/27907034/budget-impact-of-long-acting-insulin-analogues-the-case-in-brazil
#6
Fernanda O Laranjeira, Everton Nunes da Silva, Maurício G Pereira
BACKGROUND: Long-acting insulin analogues for type 1 diabetes (T1D) treatment have been available on the Brazilian market since 2002. However, the population cannot access the analogues through the public health system. OBJECTIVE: To estimate the incremental budget impact of long-acting insulin analogues coverage for T1D patients in the Brazilian public health system compared to NPH insulin. METHODS: We performed a budget impact analysis of a five-year period...
2016: PloS One
https://www.readbyqxmd.com/read/27905247/consultation-on-changes-to-technology-appraisals
#7
(no author information available yet)
A joint consultation by the National Institute for Health and Care Excellence (NICE) and NHS England sets out changes to the arrangements for evaluating and funding drugs, and for other health technologies appraised through NICE's relevant programmes. The aims of the consultation are to: » Give patients quicker access to the most cost-effective new treatments. » Offer more flexibility in the adoption of cost-effective, high-budget impact technologies in the NHS. » Provide greater clarity for patients and companies about when NICE-appraised treatments for rare conditions will automatically qualify for funding from routine commissioning budgets...
December 1, 2016: Nursing Management (Harrow)
https://www.readbyqxmd.com/read/27903558/cost-effectiveness-analysis-of-routine-pneumococcal-vaccination-in-the-uk-a-comparison-of-the-phid-cv-vaccine-and-the-pcv-13-vaccine-using-a-markov-model
#8
Emmanuelle Delgleize, Oscar Leeuwenkamp, Eleni Theodorou, Nicolas Van de Velde
OBJECTIVES: In 2010, the 13-valent pneumococcal conjugate vaccine (PCV-13) replaced the 7-valent vaccine (introduced in 2006) for vaccination against invasive pneumococcal diseases (IPDs), pneumonia and acute otitis media (AOM) in the UK. Using recent evidence on the impact of PCVs and epidemiological changes in the UK, we performed a cost-effectiveness analysis (CEA) to compare the pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) with PCV-13 in the ongoing national vaccination programme...
November 30, 2016: BMJ Open
https://www.readbyqxmd.com/read/27899957/next-generation-sequencing-in-nsclc-and-melanoma-patients-a-cost-and-budget-impact-analysis
#9
Rosa A van Amerongen, Valesca P Retèl, Veerle Mh Coupé, Petra M Nederlof, Maartje J Vogel, Wim H van Harten
Next-generation sequencing (NGS) has reached the molecular diagnostic laboratories. Although the NGS technology aims to improve the effectiveness of therapies by selecting the most promising therapy, concerns are that NGS testing is expensive and that the 'benefits' are not yet in relation to these costs. In this study, we give an estimation of the costs and an institutional and national budget impact of various types of NGS tests in non-small-cell lung cancer (NSCLC) and melanoma patients within The Netherlands...
2016: Ecancermedicalscience
https://www.readbyqxmd.com/read/27893594/sexually-transmitted-disease-program-evolution-in-response-to-changes-in-the-public-health-environment-a-massachusetts-example
#10
Marion W Carter, Katherine K Hsu, Penny S Loosier, Brandy L Peterson Maddox, Sonal R Doshi, Karen Kroeger, Kevin Cranston
BACKGROUND: In 2008, the line item supporting sexually transmitted disease (STD) services in the Massachusetts state budget was cut as a result of budget shortfalls. Shortly thereafter, direct provision of STD clinical services supported by the Massachusetts Department of Public Health (MDPH) was suspended. Massachusetts Department of Public Health requested an initial assessment of its internal response and impact in 2010. A follow-up assessment occurred in September 2013. METHODS: In 2010 and 2013, 39 and 46 staff, respectively, from MDPH and from clinical partner agencies, were interviewed about changes in the role of the MDPH, partnerships, STD services, challenges, and recommendations...
November 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27893348/cost-utility-and-budget-impact-of-methylene-blue-treated-plasma-compared-to-quarantine-plasma
#11
Joseph B Babigumira, Solomon J Lubinga, Emma Castro, Brian Custer
BACKGROUND: Methylene blue and visible light treatment and quarantine are two methods used to reduce adverse events, mostly infections, associated with the transfusion of fresh-frozen plasma. The objective of this study was to estimate and compare the budget impact and cost-utility of these two methods from a payer's perspective. MATERIALS AND METHODS: A budget impact and cost-utility model simulating the risks of hepatitis B virus, hepatitis C virus, cytomegalovirus, a West Nile virus-like infection, allergic reactions and febrile non-haemolytic transfusion reactions achieved using plasma treated with methylene blue and visible light (MBP) and quarantine plasma (QP) was constructed for Spain...
November 16, 2016: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/27892535/climate-driven-increase-of-natural-wetland-methane-emissions-offset-by-human-induced-wetland-reduction-in-china-over-the-past-three-decades
#12
Qiuan Zhu, Changhui Peng, Jinxun Liu, Hong Jiang, Xiuqin Fang, Huai Chen, Zhenguo Niu, Peng Gong, Guanghui Lin, Meng Wang, Han Wang, Yanzheng Yang, Jie Chang, Ying Ge, Wenhua Xiang, Xiangwen Deng, Jin-Sheng He
Both anthropogenic activities and climate change can affect the biogeochemical processes of natural wetland methanogenesis. Quantifying possible impacts of changing climate and wetland area on wetland methane (CH4) emissions in China is important for improving our knowledge on CH4 budgets locally and globally. However, their respective and combined effects are uncertain. We incorporated changes in wetland area derived from remote sensing into a dynamic CH4 model to quantify the human and climate change induced contributions to natural wetland CH4 emissions in China over the past three decades...
November 28, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27888437/estimated-budget-impact-of-adopting-the-affordable-care-act-s-required-smoking-cessation-coverage-on-united-states-healthcare-payers
#13
Christine L Baker, Cheryl P Ferrufino, Marianna Bruno, Stacey Kowal
INTRODUCTION: Despite abundant information on the negative impacts of smoking, more than 40 million adult Americans continue to smoke. The Affordable Care Act (ACA) requires tobacco cessation as a preventive service with no patient cost share for all FDA-approved cessation medications. Health plans have a vital role in supporting smoking cessation by managing medication access, but uncertainty remains on the gaps between smoking cessation requirements and what is actually occurring in practice...
November 25, 2016: Advances in Therapy
https://www.readbyqxmd.com/read/27886527/universal-health-coverage-at-the-macro-level-synthetic-control-evidence-from-thailand
#14
Matthias Rieger, Natascha Wagner, Arjun S Bedi
As more and more countries are moving towards Universal Health Coverage (UHC), it is important to understand the macro level or aggregate impacts of such a policy. We use synthetic control methods to study the impact of UHC, introduced in Thailand in 2001, on various macroeconomic and health outcomes. Thailand is compared to a weighted average of control countries in terms of aggregate health financing indicators, aggregate health outcomes and economic performance, over the period 1995 to 2012. Our results suggest that UHC helps alleviate the financial consequences of illnesses...
November 17, 2016: Social Science & Medicine
https://www.readbyqxmd.com/read/27885337/the-nonmydriatic-fundus-camera-in-diabetic-retinopathy-screening-a-cost-effective-study-with-evaluation-for-future-large-scale-application
#15
Giuseppe Scarpa, Francesca Urban, Stela Vujosevic, Michele Tessarin, Giovanni Gallo, Annalisa Visentin, Emanuela Foglia, Lucrezia Ferrario, Edoardo Midena
Aims. The study aimed to present the experience of a screening programme for early detection of diabetic retinopathy (DR) using a nonmydriatic fundus camera, evaluating the feasibility in terms of validity, resources absorption, and future advantages of a potential application, in an Italian local health authority. Methods. Diabetic patients living in the town of Ponzano, Veneto Region (Northern Italy), were invited to be enrolled in the screening programme. The "no prevention strategy" with the inclusion of the estimation of blindness related costs was compared with screening costs in order to evaluate a future extensive and feasible implementation of the procedure, through a budget impact approach...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27881276/the-development-of-the-romanian-scorecard-hta-system
#16
Ciprian-Paul Radu, Nona Delia Chiriac, Alexandra Mihaela Pravat
OBJECTIVES: To present the characteristics of the scorecard health technology assessment (HTA) implemented since 2014 and to show the results of this HTA process by the end of 2015. METHODS: The health care context and the Romanian HTA legislation were studied while considering the reasons behind HTA introduction, the key stakeholders, and the HTA process as a whole. A critical appraisal was done covering public HTA reports and the decisions made by the Ministry of Health...
September 2016: Value in Health Regional Issues
https://www.readbyqxmd.com/read/27881266/budget-impact-analysis-of-peritoneal-dialysis-versus-conventional-in-center-hemodialysis-in-malaysia
#17
Sunita Bavanandan, Ghazali Ahmad, Ai-Hong Teo, Lilian Chen, Frank Xiaoqing Liu
OBJECTIVES: To investigate the 5-year health care budget impact of variable distribution of adult patients treated with peritoneal dialysis (PD) and in-center hemodialysis (ICHD) on government funding in Malaysia. METHODS: An Excel-based budget impact model was constructed to assess dialysis-associated costs when changing dialysis modalities between PD and ICHD. The model incorporates the current modality distribution and accounts for Malaysian government dialysis payments and erythropoiesis-stimulating agent costs...
May 2016: Value in Health Regional Issues
https://www.readbyqxmd.com/read/27876115/the-first-digit-law-a-hypothesis-on-its-possible-impact-on-medicine-and-development-aid
#18
Gregor Pollach, Frank Brunkhorst, Mwapatsa Mipando, Felix Namboya, Samson Mndolo, Thomas Luiz
The "first digit law" or "Benford's law" is a mathematical distribution discovered by Simon Newcomb and Frank Benford. It states, that the probability of the leading number d (d∈{1,…,9}) in many natural datasets follows: P (d)=log10 (d+1)-log10 (d)=log10 (1+1/d). It was successfully used through tax authorities and "forensic accounting" in order to detect fraud and other irregularities. Benfords law was almost neglected for its use outside financial accounting. The planning for health care systems in developing countries is extremely dependant on good, valid data...
December 2016: Medical Hypotheses
https://www.readbyqxmd.com/read/27875228/performance-evaluation-and-optimal-detection-of-relay-assisted-diffusion-based-molecular-communication-with-drift
#19
Nooshin Tavakkoli, Paeiz Azmi, Nader Mokari
In this paper, we consider a decode-and-forward (DF) relay-assisted diffusion-based molecular communication system inside one of the blood vessels of a human body with positive drift from transmitter to receiver. We use the normal approximation to the distribution of the number of received molecules and derive a closed-form expression for the end-toend bit error probability of the system. We then propose an optimization problem that aims at minimizing the bit error probability of the system and solve it at the receiver nanomachine by an algorithm based on the bisection method to determine the optimal detection threshold...
November 16, 2016: IEEE Transactions on Nanobioscience
https://www.readbyqxmd.com/read/27871537/-1-8-million-and-counting-how-volatile-agent-education-has-decreased-our-spending-1000-per-day
#20
Scott A Miller, Carol A Aschenbrenner, Justin R Traunero, Loren A Bauman, Samuel S Lobell, Jeffrey S Kelly, John E Reynolds
STUDY OBJECTIVE: Volatile anesthetic agents comprise a substantial portion of every hospital's pharmacy budget. Challenged with an initiative to lower anesthetic drug expenditures, we developed an education-based intervention focused on reducing volatile anesthetic costs while preserving access to all available volatile anesthetics. When postintervention evaluation demonstrated a dramatic year-over-year reduction in volatile agent acquisition costs, we undertook a retrospective analysis of volatile anesthetic purchasing data using time series analysis to determine the impact of our educational initiative...
December 2016: Journal of Clinical Anesthesia
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