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https://www.readbyqxmd.com/read/28545094/economic-evaluation-of-policy-options-for-dialysis-in-end-stage-renal-disease-patients-under-the-universal-health-coverage-in-indonesia
#1
Afiatin, Levina Chandra Khoe, Erna Kristin, Lusiana Siti Masytoh, Eva Herlinawaty, Pitsaphun Werayingyong, Mardiati Nadjib, Sudigdo Sastroasmoro, Yot Teerawattananon
OBJECTIVES: This study aims to assess the value for money and budget impact of offering hemodialysis (HD) as a first-line treatment, or the HD-first policy, and the peritoneal dialysis (PD) first policy compared to a supportive care option in patients with end-stage renal disease (ESRD) in Indonesia. METHODS: A Markov model-based economic evaluation was performed using local and international data to quantify the potential costs and health-related outcomes in terms of life years (LYs) and quality-adjusted life years (QALYs)...
2017: PloS One
https://www.readbyqxmd.com/read/28539212/improved-adherence-to-a-stepped-care-model-reduces-costs-of-intermittent-claudication-treatment-in-the-netherlands
#2
D Hageman, H J P Fokkenrood, P P M Essers, M J W Koelemay, J C Breek, A C Vahl, M R M Scheltinga, J A W Teijink
OBJECTIVE/BACKGROUND: A previous budget impact analysis regarding a supervised exercise therapy (SET) first treatment strategy (stepped care model [SCM]) for Dutch patients with intermittent claudication (IC) showed a low referral rate in 2009, despite solid evidence of the effectiveness of SET programs. Recently, several campaigns have stimulated stakeholders in the field to adopt a SET first strategy in patients with IC. The aim of the present study was to reassess SCM adherence after a 2 year period...
May 20, 2017: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28522924/use-of-the-4kscore-test-to-predict-the-risk-of-aggressive-prostate-cancer-prior-to-prostate-biopsy-overall-cost-savings-and-improved-quality-of-care-to-the-us-healthcare-system
#3
Jeffrey D Voigt, Yan Dong, Vincent Linder, Stephen Zappala
The 4Kscore® Test (BioReference Laboratories, Elmwood Park, NJ) is a blood test that accurately determines the risk of aggressive prostate cancer and significantly reduces prostate biopsies and associated overdiagnosis and overtreatment of indolent cancer. A budget impact model was developed to test the hypothesis that the 4Kscore Test can improve quality of care and deliver cost savings for patients who are suspected of having prostate cancer and would otherwise undergo prostate biopsy under the current standard of care (SOC) in the United States...
2017: Reviews in Urology
https://www.readbyqxmd.com/read/28516201/budget-impact-and-cost-effectiveness-analyses-of-direct-acting-antivirals-for-chronic-hepatitis-c-virus-infection-in-hong-kong
#4
X Li, N S Chan, A W Tam, I F N Hung, E W Chan
The purpose of this investigation was to evaluate the budget impact and cost-effectiveness of direct-acting antivirals (DAAs) for the treatment of hepatitis C virus (HCV) infection in Hong Kong. A decision analytic model was developed to compare short-term costs and health outcomes of patients with chronic HCV genotype 1 infection in Hong Kong who were treated with an interferon (INF)-based treatment (dual therapy of pegylated interferon and ribavirin) or DAA-based treatments (sofosbuvir or ledipasvir/sofosbuvir or ombitasvir/paritaprevir/ritonavir plus dasabuvir)...
May 17, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28515870/behavioral-responses-to-encounter-of-fishing-boats-in-wandering-albatrosses
#5
Julien Collet, Samantha C Patrick, Henri Weimerskirch
Animals are attracted to human food subsidies worldwide. The behavioral response of individuals to these resources is rarely described in detail, beyond chances of encounters. Seabirds for instance scavenge in large numbers at fishing boats, triggering crucial conservation issues, but how the response to boats varies across encounters is poorly known. Here we examine the behavioral response of wandering albatrosses (Diomedea exulans), equipped with GPS tags, to longline fishing boats operating near their colony for which we had access to vessel monitoring system data...
May 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28511791/-usefulness-of-the-budget-and-the-balanced-scorecard-in-managing-primary-care-centres-impact-on-staff-motivation
#6
Juan Manuel Ramón-Jerónimo, Raquel Flórez-López, Natalia Domínguez-Lario
OBJECTIVE: To analyse the utility perceived by managers of centers of primary care about management tools (budget and balanced scorecard), together their impact on human resources motivation. DESIGN: Qualitative study (case study) based on grounded theory performed between January and June 2014. LOCATION: Units of Clinical Management of Primary Health (UGCAP) in Metropolitan Health Area of Seville, Spain. PARTICIPANTS: UGCAP managers and Health Area (CEO) managers...
May 13, 2017: Atencion Primaria
https://www.readbyqxmd.com/read/28510591/the-case-for-investing-in-the-male-condom
#7
John Stover, James E Rosen, Maria Nadia Carvalho, Eline L Korenromp, Howard S Friedman, Matthew Cogan, Bidia Deperthes
When used correctly and consistently, the male condom offers triple protection from unintended pregnancy and the transmission of sexually transmitted infections (STIs) and human immunodeficiency virus (HIV). However, with health funding levels stagnant or falling, it is important to understand the cost and health impact associated with prevention technologies. This study is one of the first to attempt to quantify the cost and combined health impact of condom use, as a means to prevent unwanted pregnancy and to prevent transmission of STIs including HIV...
2017: PloS One
https://www.readbyqxmd.com/read/28499861/the-cost-effectiveness-of-high-risk-lung-cancer-screening-and-drivers-of-program-efficiency
#8
Sonya Cressman, Stuart J Peacock, Martin C Tammemagi, William K Evans, Natasha B Leighl, John R Goffin, Alain Tremblay, Geoffrey Liu, Daria Manos, Paul MacEachern, Rick Bhatia, Serge Puksa, Garth Nicholas, Annette McWilliams, John R Mayo, John Yee, John C English, Reka Pataky, Emily McPherson, Sukhinder Atkar-Khattra, Michael R Johnston, Heidi Schmidt, Frances A Shepherd, Kam Soghrati, Kayvan Amjadi, Paul Burrowes, Christian Couture, Harmanjatinder S Sekhon, Kazuhiro Yasufuku, Glenwood Goss, Diana N Ionescu, David M Hwang, Simon Martel, Don D Sin, Wan C Tan, Stefan Urbanski, Zhaolin Xu, Ming-Sound Tsao, Stephen Lam
BACKGROUND: Lung cancer risk prediction models have the potential to make programs more affordable; however, the economic evidence is limited. METHODS: Participants in the National Lung Cancer Screening Trial (NLST) were retrospectively identified with the PLCOm2009 risk-prediction tool. The high-risk subgroup was assessed for lung cancer incidences and demographic character compared with the low-risk subgroup and the Pan-Canadian Early Detection of Lung Cancer Study (PanCan)-an observational study, that was high-risk selected in Canada...
May 9, 2017: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/28493177/what-is-single-payer-health-care-a-review-of-definitions-and-proposals-in-the-u-s
#9
Jodi L Liu, Robert H Brook
BACKGROUND: Single-payer systems have been proposed as a health care reform alternative in the United States. However, there is no consensus on the definition of single-payer. Most definitions characterize single-payer as one entity that collects funds and pays for health care on behalf on an entire population. Increased flexibility for state health care reform may provide opportunities for state-based single-payer systems to be considered. OBJECTIVE: To explore the concept of single-payer and to describe the contents of single-payer health care proposals...
May 10, 2017: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/28492784/budget-impact-analysis
#10
Marcus Tolentino Silva, Everton Nunes da Silva, Maurício Gomes Pereira
No abstract text is available yet for this article.
April 2017: Epidemiologia e Servicos de Saude: Revista do Sistema Unico de Saude do Brasil
https://www.readbyqxmd.com/read/28492533/gene-patents-still-alive-and-kicking-their-impact-on-provision-of-genetic-testing-for-long-qt-syndrome-in-the-canadian-public-health-care-system
#11
Sarah E Ali-Khan, E Richard Gold
PurposeAlthough the Supreme Court of the United States limited their availability in Association for Molecular Pathology v. Myriad Genetics, gene patents remain important around the world. We examine the situation in Canada, where gene patents continue to exist, in light of recent litigation relating to familial long QT syndrome (LQTS).MethodsWe conducted in-depth semistructured interviews with 25 stakeholders across five Canadian provinces and supplemented this with a case analysis of the litigation.ResultsThe majority of LQTS testing was carried out outside Canada...
May 11, 2017: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/28488061/the-effects-of-environmental-factors-on-the-efficiency-of-clinical-commissioning-groups-in-england-a-data-envelopment-analysis
#12
Rumbidzai Takundwa, Sue Jowett, Hugh McLeod, Maria Cristina Peñaloza-Ramos
Clinical Commissioning Groups (CCGs) were created in 2013 to make the NHS more responsive, efficient and accountable. A large number of different indicators can be used to measure the quality and outcomes of services provided by CCGs, however there is currently no single measure of overall efficiency available. The performance of CCGs may also be confounded by environmental factors such as deprivation, population size and burden of disease. Data Envelopment Analysis (DEA) is a linear programming technique that can be used to measure the relative efficiency of a given set of organisations...
June 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/28487098/describing-wait-time-bottlenecks-for-ed-patients-undergoing-head-ct
#13
Jonathan G Rogg, Robert Huckman, Michael Lev, Ali Raja, Yuchiao Chang, Benjamin A White
STUDY OBJECTIVES: Facing increased utilization and subsequent capacity and budget constraints, ED's must better understand bottlenecks and their effect on process flow to improve process efficiency. The primary objective of this study was to identify bottlenecks in obtaining a head CT and investigate patient waiting time based on those bottlenecks. METHODS: This observational study included all patients undergoing a head CT between July 1, 2013 and June 30, 2014 at a large, urban academic ED with over 100,000 visits per year...
May 1, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28484809/novel-fast-analytical-method-for-indirect-determination-of-mcpd-fatty-acid-esters-in-edible-oils-and-fats-based-on-simultaneous-extraction-and-derivatization
#14
Renata Jędrkiewicz, Agnieszka Głowacz-Różyńska, Justyna Gromadzka, Piotr Konieczka, Jacek Namieśnik
A novel method for indirect determination of MCPD esters levels in lipid samples has been developed. The method is based on combination of extraction and derivatization in the same sample preparation step. It is achieved by the application of diethyl ether as extraction solvent for isolation of analytes released from esterified forms from the water phase and as dilution solvent for solid PBA - the derivatization agent. It is a noteworthy improvement of recommended indirect approaches available in the literature because such steps as sample clean-up, multiple liquid-liquid extractions, and preconcentration are excluded in the proposed solution...
May 8, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28482116/pollution-tolerant-invertebrates-enhance-greenhouse-gas-flux-in-urban-wetlands
#15
Andrew S Mehring, Perran L M Cook, Victor Evrard, Stanley B Grant, Lisa A Levin
One of the goals of urban ecology is to link community structure to ecosystem function in urban habitats. Pollution-tolerant wetland invertebrates have been shown to enhance greenhouse gas (GHG) flux in controlled laboratory experiments, suggesting that they may influence urban wetland roles as sources or sinks of GHG. However, it is unclear if their effects can be detected in highly variable conditions in a field setting. Here we use an extensive dataset on carbon dioxide (CO2 ), methane (CH4 ), and nitrous oxide (N2 O) flux in sediment cores (n = 103) collected from ten urban wetlands in Melbourne, Australia during summer and winter in order to test for invertebrate enhancement of GHG flux...
May 8, 2017: Ecological Applications: a Publication of the Ecological Society of America
https://www.readbyqxmd.com/read/28477220/defining-and-measuring-the-affordability-of-new-medicines-a-systematic-review
#16
REVIEW
Fernando Antoñanzas, Robert Terkola, Paul M Overton, Natalie Shalet, Maarten Postma
BACKGROUND: In many healthcare systems, affordability concerns can lead to restrictions on the use of expensive efficacious therapies. However, there does not appear to be any consensus as to the terminology used to describe affordability, or the thresholds used to determine whether new drugs are affordable. OBJECTIVES: The aim of this systematic review was to investigate how affordability is defined and measured in healthcare. METHODS: MEDLINE, EMBASE and EconLit databases (2005-July 2016) were searched using terms covering affordability and budget impact, combined with definitions, thresholds and restrictions, to identify articles describing a definition of affordability with respect to new medicines...
May 5, 2017: PharmacoEconomics
https://www.readbyqxmd.com/read/28472460/did-contracting-effect-the-use-of-primary-health-care-units-in-pakistan
#17
Muhammad Ashar Malik, Ellen Van de Poel, Eddy Van Doorslaer
For many years, Pakistan has had a wide network of Basic Health Units spread across the country, but their utilization by the population in rural and peri-urban areas has remained low. As of 2004, in an attempt to improve the utilization and performance of these public primary healthcare facilities, the government has gradually started contracting-in intergovernmental organizations to manage these BHUs. Using five nationally representative household surveys conducted between 2001 and 2012, and exploiting the gradual roll-out of this reform to apply a difference-in-difference approach, we evaluate its impact on BHU utilization...
May 3, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/28470542/a-comparative-analysis-of-a-disposable-and-a-reusable-pedicle-screw-instrument-kit-for-lumbar-arthrodesis-integrating-hta-and-mcda
#18
Claudia Ottardi, Alessio Damonti, Emanuele Porazzi, Emanuela Foglia, Lucrezia Ferrario, Tomaso Villa, Enrico Aimar, Marco Brayda-Bruno, Fabio Galbusera
OBJECTIVE: Lumbar arthrodesis is a common surgical technique that consists of the fixation of one or more motion segments with pedicle screws and rods. However, spinal surgery using these techniques is expensive and has a significant impact on the budgets of hospitals and Healthcare Systems. While reusable and disposable instruments for laparoscopic interventions have been studied in literature, no specific information exists regarding instrument kits for lumbar arthrodesis. The aim of the present study was to perform a complete health technology assessment comparing a disposable instrument kit for lumbar arthrodesis (innovative device) with the standard reusable instrument...
December 2017: Health Economics Review
https://www.readbyqxmd.com/read/28464797/modeling-the-patient-and-health-system-impacts-of-alternative-xpert%C3%A2-mtb-rif-algorithms-for-the-diagnosis-of-pulmonary-tuberculosis-in-addis-ababa-ethiopia
#19
Abraham Tesfaye, Daniel Fiseha, Dawit Assefa, Eveline Klinkenberg, Silvia Balanco, Ivor Langley
BACKGROUND: To reduce global tuberculosis (TB) burden, the active disease must be diagnosed quickly and accurately and patients should be treated and cured. In Ethiopia, TB diagnosis mainly relies on spot-morning-spot (SMS) sputum sample smear analysis using Ziehl-Neelsen staining techniques (ZN). Since 2014 targeted use of xpert has been implemented. New diagnostic techniques have higher sensitivity and are likely to detect more cases if routinely implemented. The objective of our study was to project the effects of alternative diagnostic algorithms on the patient, health system, and costs, and identify cost-effective algorithms that increase TB case detection in Addis Ababa, Ethiopia...
May 2, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28464584/-the-impact-of-broadened-diagnostic-criteria-on-the-prevalence-of-hypertension-hyperlipidemia-and-diabetes-mellitus-in-china
#20
X F Hu, X R Han, Z Y Yang, Y H Hu, J L Tang
Objective: The burden of chronic disease has been continuously increasing in China since the early 1980s. Besides the worsening of risk factors, the change in diagnostic criteria is very likely an important explanation for the increase in the prevalence of hypertension, hyperlipidemia and diabetes mellitus, three commonest, major chronic conditions that can lead to major vascular events and deaths. This study aims to estimate the contribution of changes in diagnostic criteria to the increase in the prevalence of the three conditions in China...
May 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
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