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Haemorrhage

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https://www.readbyqxmd.com/read/29029180/cerebral-strokes-in-children-on-intracorporeal-ventricular-assist-devices-analysis-of-the-euromacs-registry
#1
Martin Schweiger, Oliver Miera, Theo M M H de By, Michael Hübler, Felix Berger, Mustafa Özbaran, Antonio Loforte, Burkhardt Seifert, Gaetano Gargiulo, Jan Gummert, Paul Mohacsi
OBJECTIVES: Little is known about cerebral strokes in paediatric patients supported by intracorporeal continuous-flow ventricular assist devices. METHODS: We retrospectively investigated patients younger than 19 years of age who were treated with an intracorporeal continuous-flow ventricular assist device in the European Registry for Patients with Mechanical Circulatory Support (EUROMACS) database. The patients were stratified by body surface area in Group 1 [<1...
September 25, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29028804/a-recombinase-polymerase-amplification-assay-for-rapid-detection-of-crimean-congo-haemorrhagic-fever-virus-infection
#2
Laura C Bonney, Robert J Watson, Babak Afrough, Manija Mullojonova, Viktoriya Dzhuraeva, Farida Tishkova, Roger Hewson
BACKGROUND: Crimean-Congo Haemorrhagic fever Virus (CCHFV) is a rapidly emerging vector-borne pathogen and the cause of a virulent haemorrhagic fever affecting large parts of Europe, Africa, the Middle East and Asia. METHODOLOGY/PRINCIPLE FINDINGS: An isothermal recombinase polymerase amplification (RPA) assay was successfully developed for molecular detection of CCHFV. The assay showed rapid (under 10 minutes) detection of viral extracts/synthetic virus RNA of all 7 S-segment clades of CCHFV, with high target specificity...
October 13, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29026632/salmonella-oranienburg-haemorrhagic-cystitis-in-an-immunocompetent-young-male
#3
Jiasian Teh, Mark Quinlan, Damien Bolton
Introduction. Non-typhoidal salmonella (NTS) bacteriuria is extremely rare. Haemorrhagic cystitis is defined by urinary symptoms including haematuria, frequency, urgency and dysuria. Reports of haemorrhagic cystitis caused by NTS are exceptionally uncommon, especially in immunocompetent, young, male patients. Case presentation. A 27-year-old male with no past medical history presented to the Emergency Department with a 24 h history of visible haematuria having returned five days earlier from a five month trip across South America...
August 2017: JMM Case Reports
https://www.readbyqxmd.com/read/29026384/clinical-and-cranial-computed-tomography-scan-findings-in-adults-following-road-traffic-accidents-in-kampala-uganda
#4
Geoffrey Erem, Samuel Bugeza, Elsie Kiguli Malwadde
BACKGROUND: Globally, road traffic accidents are a major cause of death and disability. The developing countries bear a disproportionately large share of the RTAs which account for about 85% of the deaths. Most of these RTAs result in head injury, which globally, most scholars and medical practitioners consider a significant economic, social and medical problem. In Mulago National referral hospital, RTA is the leading cause of surgical admission. OBJECTIVE: To describe the cranial computed tomography (CT) scan findings in adults following RTA in Mulago hospital...
March 2017: African Health Sciences
https://www.readbyqxmd.com/read/29025918/contemporary-endovascular-and-open-aneurysm-treatment-in-the-era-of-flow-diversion
#5
REVIEW
Marcus D Mazur, Philipp Taussky, Min S Park, William T Couldwell
Clinical outcomes have improved considerably over the last decade for patients with ruptured and unruptured aneurysms. Modern endovascular techniques, such as flow diversion, are associated with high aneurysm occlusion rates and have become a popular treatment modality for many types of aneurysms. However, the safety and effectiveness of flow diversion has not yet been established in trials comparing it with traditional aneurysm treatments. Moreover, there are some types of aneurysms that may not be appropriate for endovascular coiling, such as wide-necked aneurysms located at branch points of major vessels, large saccular aneurysms with multiple efferent arteries, dolichoectatic aneurysms, large aneurysms with mass effect, when there are technical complications with endovascular treatment, when patients cannot tolerate or have contraindications to antiplatelet therapy or in the setting of a subarachnoid haemorrhage...
October 12, 2017: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29025850/protocol-for-a-pilot-randomised-double-blinded-placebo-controlled-trial-of-prophylactic-use-of-tranexamic-acid-for-preventing-postpartum-haemorrhage-tapph-1
#6
Asim Alam, Ameya Bopardikar, Shelly Au, Jon Barrett, Jeannie Callum, Alex Kiss, Stephen Choi
INTRODUCTION: Postpartum haemorrhage (PPH) is the leading cause of maternal morbidity and mortality worldwide. Despite the availability of multiple uterotonic agents, the incidence of PPH continues to rise. Tranexamic acid (TXA) has been shown to be a safe, effective and inexpensive therapeutic option for the treatment of PPH, however, its use prophylactically in mitigating the risk of PPH is unknown. This pragmatic randomised prospective trial assesses the feasibility and safety of administering TXA at the time of delivery for the prevention of PPH...
October 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/29025450/an-increase-in-rates-of-obstetric-haemorrhage-in-a-setting-of-high-hiv-seroprevalence
#7
E Shabalala, Hannah M Sebitloane
BACKGROUND: Obstetric haemorrhage (OH) is the leading cause of maternal mortality worldwide, although, indirectly, HIV is also a leading cause of maternal mortality in some settings with a high HIV seroprevalence. OBJECTIVE: To determine the possible association between increasing rates of OH and HIV or its treatment. METHODS: We conducted a retrospective chart review of women with OH at King Edward VIII Hospital, Durban, South Africa, over a 3-year period (2009 - 2011), during which the drug regimen for the prevention of mother-to-child transmission was evolving from single-dose nevirapine to antenatal zidovudine combined with intrapartum nevirapine (also referred to as dual therapy), and finally to a combination or highly active antiretroviral therapy (cART or HAART)...
June 30, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/29025396/a-description-of-the-gross-pathology-of-drowning-and-other-causes-of-mortality-in-seabirds
#8
Victor R Simpson, David N Fisher
BACKGROUND: Mortality of seabirds due to anthropogenic causes, especially entrapment in fishing gear, is a matter of increasing international concern. This study aimed at characterising the gross pathology of seabirds that drowned in fishing nets and comparing it with that in other common causes of mortality. RESULTS: Post-mortem examinations were performed on 103 common guillemots, 32 razorbills, 37 shags and 5 great northern divers found stranded in Cornwall during 1981-2016...
October 12, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29024839/hepatic-artery-aneurysm-causing-gastrointestinal-haemorrhage-case-report-and-literature-review
#9
Saulius Palubinskas, Simon Ladefoged Rasmussen
INTRODUCTION: True hepatic artery aneurysms (HAAs) are rare, and when complicated by gastrointestinal haemorrhage, it becomes an even rarer disease entity. The mortality is high and imaging may fail to provide the diagnosis. We present a case of a true hepatic artery aneurysm complicated by a fistula to the duodenum which was first recognised during surgery. PRESENTATION OF CASE: A 77-year-old man presented with upper gastrointestinal haemorrhage. Upper endoscopy revealed an ulceration in the duodenal bulb, which was refractory to endoscopic treatment...
October 4, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29024773/an-improved-technique-for-the-assessment-of-venom-induced-haemorrhage-in-a-murine-model
#10
Timothy P Jenkins, Andrés Sánchez, Álvaro Segura, Mariángela Vargas, María Herrera, Trenton K Stewart, Guillermo León, José María Gutiérrez
Haemorrhage is a common clinical manifestation in envenomings caused by bites from snakes of the family Viperidae. Therefore, knowing the haemorrhagic potential of venoms and the capacity of antivenoms to neutralise this effect are of paramount relevance in toxinology. The most widely used method for quantifying haemorrhage involves the intradermal injection of venom (or a mixture of venom/antivenom) in mice, and the assessment of the resulting haemorrhagic area in the inner side of the skin. Although this method allows a straightforward assessment of the haemorrhagic activity of a venom, it does not account for haemorrhagic lesions having a similar area but differing in the depth and intensity of haemorrhage...
October 9, 2017: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/29024280/laparoscopic-pancreaticoduodenectomy-in-brisbane-australia-an-initial-experience
#11
Bhavik Patel, Universe Leung, Jerry Lee, Richard Bryant, Nicholas O'Rourke, David Cavallucci
BACKGROUND: The role of minimally invasive approach for pancreaticoduodenectomy has not yet been well defined in Australia. We present our early experience with laparoscopic pancreaticoduodenectomy (LPD) from Brisbane, Australia. METHODS: Retrospective review in a prospectively collected database of patients undergoing LPD between 2006 and 2016 was performed. Patients who underwent a hybrid LPD (HLPD) mobilization approach and resection followed by open reconstruction and totally LPD (TLPD) approach were included in this study...
October 11, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/29023857/preceding-haemorrhagic-shock-as-a-detrimental-risk-factor-for-respiratory-distress-after-excessive-allogeneic-blood-transfusion
#12
R Masuda, T Iijima, R Kondo, Y Itoda, M Matsuhashi, S Hashimoto, T Kohira, N Kobayashi, H Okazaki
BACKGROUND AND OBJECTIVES: Whether transfusion-associated circulatory overload arises as a simple result of over-transfusion or requires another trigger remains unclear. Here, we examined whether respiratory distress could be reproduced by massive transfusion alone in an animal model. MATERIALS AND METHODS: A total of 20 anaesthetized swine were equipped with monitors. Allogeneic blood was obtained from 10 donor swine. A 4-stage loading protocol with each stage equivalent to 25% of the blood volume (BV) in the recipient swine was then used to infuse crystalloid (CR), hydroxyethyl starch (HES) or allogeneic blood (TR) (n = 5 each)...
October 11, 2017: Vox Sanguinis
https://www.readbyqxmd.com/read/29023812/polycystic-liver-disease-hepatic-venous-outflow-obstruction-lesions-of-the-non-cystic-parenchyma-have-major-consequences
#13
Louise Barbier, Maxime Ronot, Béatrice Aussilhou, François Cauchy, Claire Francoz, Prof Valérie Vilgrain, Olivier Soubrane, Valérie Paradis, Jacques Belghiti
BACKGROUND: In patients with polycystic liver disease, development of cysts induces hepatic venous outflow obstruction (HVOO) and parenchymal modifications, challenging the paradigm of a normal non-cystic liver parenchyma. The aims were to reappraise the pathology of the non-cystic parenchyma, by focusing on HVOO lesions; and to investigate the association with outflow obstruction at imaging and perioperative course after liver resection. METHODS: This is a retrospective study conducted in one tertiary center between 1993 and 2014...
October 10, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/29022962/retinal-necrosis-as-the-initial-presentation-of-primary-intraocular-lymphoma
#14
Parthopratim Dutta Majumder, Nirupama Raghothaman, Ranju Kharel, Nitin Kumar, Vikas Khetan
A 72 years old female presented with bilateral painless progressive loss of vision over one year. She was diagnosed as non-resolving bilateral panuveitis. Her visual acuity in right eye was hand movement close to face and left eye was perception of light with inaccurate projection of rays. Bilateral anterior chamber had 1+ cells and flares. Vitreous cells had 1+ cells and haze in right eye but the left eye had 3+ vitreous cells and haze. Right eye fundus had multiple, discrete sub retinal yellowish deposits with subretinal haemorrhage and macular edema with perivascular infiltrates...
January 2017: Nepalese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29022794/an-assessment-of-pelvic-binder-placement-at-a-uk-major-trauma-centre
#15
H Naseem, P D Nesbitt, D C Sprott, A Clayson
Introduction Pelvic binders are used to reduce the haemorrhage associated with pelvic ring injuries. Application at the level of the greater trochanters is required. We assessed the frequency of their use in patients with pelvic ring injuries and their positioning in patients presenting to a single major trauma centre. Methods A retrospective review of our trauma database was performed to randomly select 1000 patients for study from April 2012 to December 2016. Patients with a pelvic binder or a pelvic ring injury defined by the Young and Burgess classification were included...
September 15, 2017: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/29022536/short-term-outcomes-of-inborn-v-outborn-very-low-birth-weight-neonates-1-500-g-in-the-neonatal-nursery-at-groote-schuur-hospital-cape-town-south-africa
#16
L Gibbs, L Tooke, M C Harrison
BACKGROUND: The Groote Schuur Hospital (GSH) neonatal nursery provides level 3 care for the Metro West Health District in the Western Cape Province of South Africa. Worldwide, very-low-birth-weight (VLBW) neonates delivered in level 3 neonatal units have better outcomes than those transported from other facilities. OBJECTIVES: To identify the characteristics and outcomes of VLBW neonates at GSH, with emphasis on differences between inborns and outborns. METHODS: This was a retrospective cohort study...
September 22, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/29021873/comparative-study-of-proximal-tibia-and-iliac-crest-bone-graft-donor-sites-in-treatment-of-orthopaedic-pathologies
#17
O N Salawu, O M Babalola, B A Ahmed, G H Ibraheem, D M Kadir
Introduction: Bone graft is harvested from bone and used to stimulate bone healing due to its properties. The aims of the study were to compare the quantity of graft harvested from proximal tibia and iliac crest, and the complications at these donor sites. Materials and Methods: This was a prospective study carried out on all consecutive patients who had orthopaedic procedures that required bone grafting at the study centre, from April, 2015 to March, 2016. Results: During the study period, 86 patients were recruited; 43 of these patients had bone graft harvested from the proximal tibia, while the other 43 patients had graft harvested from the iliac crest...
July 2017: Malaysian Orthopaedic Journal
https://www.readbyqxmd.com/read/29021140/fulminant-bacillus-cereus-septicaemia-with-multiple-organ-ischaemic-haemorrhagic-complications-in-a-patient-undergoing-chemotherapy-for-acute-myelogenous-leukaemia
#18
Yusuke S Hori, Satoshi Kodera, Yurie Nagai, Yoshio Suzuki
Bacillus cereus is a Gram-positive spore-forming rod widely found in the environment and is thought to be a frequent source of contamination. This micro-organism is reportedly a significant pathogenic agent among immunocompromised individuals. Furthermore, multiple cases of fulminant septicaemia have been reported among individuals receiving chemotherapy for acute myelogenous leukaemia. In some cases, B. cereus septicaemia was associated with multiple haemorrhages. We, herein, describe a patient with an extremely acute course of B...
October 10, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29020935/a-retrospective-cohort-study-to-predict-severe-dengue-in-honduran-patients
#19
Eduardo Fernández, Marek Smieja, Stephen D Walter, Mark Loeb
BACKGROUND: An important challenge in the identification of dengue is how to predict which patients will go on to experience severe illness, which is typically characterized by fever, thrombocytopenia, haemorrhagic manifestations, and plasma leakage. Accurate prediction could result in the appropriate hospital triage of high risk patients. The objective of this study was to identify clinical factors observed within the first 24 h of hospital admission that could predict subsequent severe dengue...
October 11, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29020700/a-case-report-of-delayed-intra-abdominal-and-intra-luminal-haemorrhage-after-polypectomy
#20
Albrecht Neesse, Marian Grade, Sebastian Dango, Michael Ghadimi, Volker Ellenrieder, Steffen Kunsch, Ahmad Amanzada
We report the case of a 70-year-old man who presented with hematochezia, anaemia, and severe abdominal pain 6 days after polypectomy. Contrast-enhanced ultrasound and computed tomography revealed no signs of free intra-abdominal air but showed intra-abdominal and intra-luminal bleeding. The patient was referred to colonoscopy in the operation room, which showed a coagula and venous bleeding at the polypectomy site. Emergency laparotomy was performed and revealed a large intra-abdominal mesocolic hematoma, which was surgically removed...
October 2017: Zeitschrift Für Gastroenterologie
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