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https://www.readbyqxmd.com/read/29666657/the-effects-of-aloe-vera-cream-on-the-expression-of-cd4-and-cd8-lymphocytes-in-skin-wound-healing
#1
Yos Adi Prakoso, Kurniasih
The aim of this study is to explore the effect of topical application of Aloe vera on skin wound healing. Thirty-six male Sprague-Dawley rats weighing 150-200 grams were divided into four groups. All groups were anesthetized, shaved, and exposed to round full-thickness punch biopsy on the back: group I (control); group II (treated with 1% Aloe vera cream); group III (treated with 2% Aloe vera cream); and group IV (treated with madecassol®). The treatments were given once a day. Macroscopic and microscopic examination were observed at 5, 10, and 15 days after skin biopsy...
2018: Journal of Tropical Medicine
https://www.readbyqxmd.com/read/29656090/naturally-occurring-compounds-in-differentiation-based-therapy-of-cancer
#2
REVIEW
Sanja Mijatović, Alessia Bramanti, Ferdinando Nicoletti, Paolo Fagone, Goran Kaluđerović, Danijela Maksimović-Ivanić
Differentiation of cancer cells entails the reversion of phenotype from malignant to the original. The conversion to cell type characteristic for another tissue is named transdifferentiation. Differentiation/transdifferentiation of malignant cells in high grade tumor mass could serve as a nonaggressive approach that potentially limits tumor progression and augments chemosensitivity. While this therapeutic strategy is already being used for treatment of hematological cancers, its feasibility for solid malignancies is still debated...
April 12, 2018: Biotechnology Advances
https://www.readbyqxmd.com/read/29649056/topical-aloe-vera-gel-for-accelerated-wound-healing-of-split-thickness-skin-graft-donor-sites-a-double-blind-randomized-controlled-trial-and-systematic-review
#3
Chairat Burusapat, Monlada Supawan, Chatchai Pruksapong, Anont Pitiseree, Chaichoompol Suwantemee
BACKGROUND: Aloe vera has been used to treat wounds since ancient times. However, the efficacy of Aloe vera for burns and split-thickness skin graft (STSG) donor sites are inconclusive. METHODS: A double-blind, randomized, controlled trial was conducted. Patients who underwent STSG harvesting from the thigh were included. STSG donor sites were divided into two groups: Aloe vera group and placebo group. The visual analogue scale (VAS) score evaluated pain and complete epithelialization was assessed...
March 30, 2018: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29621403/amelioration-of-diabetes-induced-diabetic-nephropathy-by-aloe-vera-implication-of-oxidative-stress-and-hyperlipidemia
#4
Mandeep Kumar Arora, Yogesh Sarup, Ritu Tomar, Mary Singh, Puspendra Kumar
This study investigated the effect of Aloe vera in diabetes-induced nephropathy in rats. As diabetes-associated hyperlipidemia and oxidative stress have been implicated in the pathogenesis of diabetic nephropathy, we evaluated the protective effect of whole leaf extract of Aloe vera on the basis of its hypolipidemic and antioxidative property. Aloe vera (300 mg/kg orally) has been noted to possess renoprotective effect in experimental diabetic nephropathy. However, its mechanism is not fully understood. Rats were administered streptozotocin (STZ) (55 mg/kg intraperitoneally once) to induce experimental diabetes mellitus...
April 5, 2018: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/29609456/retraction-of-excavating-the-role-of-aloe-vera-wrapped-mesoporous-hydroxyapatite-frame-ornamentation-in-newly-architectured-polyurethane-scaffolds-for-osteogenesis-and-guided-bone-regeneration-with-microbial-protection
#5
M Selvakumar, Harpreet Singh Pawar, Nimmy K Francis, Bodhisatwa Das, Santanu Dhara, Santanu Chattopadhyay
No abstract text is available yet for this article.
April 3, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29579070/encountering-epidemic-effects-of-leaf-spot-disease-alternaria-brassicae-on-aloe-vera-by-fungal-biocontrol-agents-in-agrifields-an-ecofriendly-approach
#6
Swapan Kumar Ghosh, Subhankar Banerjee, Sujoy Pal, Niloy Chakraborty
Aloe vera (L.) Burm.f. is a highly important and extensively cultivated medicinal plant and that is also extensively used in the cosmetic industry. It has been frequently reported to suffer from Alternaria leaf spot disease in various parts of the world. Various fungicides used to combat this disease, have deleterious effects on the environment and on pharmacologically important constituents of Aloe vera. To avoid the harmful effects of fungicides an ecofriendly approach has been adopted here. A weekly survey was conducted during 2013-2015 in and around North 24 Parganas (West Bengal) to obtain the percentage of disease index (PDI)...
2018: PloS One
https://www.readbyqxmd.com/read/29549275/schizophyllum-commune-induced-genotoxic-and-cytotoxic-effects-in-spodoptera-litura
#7
Mandeep Kaur, Pooja Chadha, Sanehdeep Kaur, Amarjeet Kaur, Rajvir Kaur, Arun Kumar Yadav, Ramandeep Kaur
In search for ecofriendly alternatives to chemical insecticides the present study was conducted to assess the insecticidal potential of an endophytic fungus Schizophyllum commune and its mechanism of toxicity by studying genotoxic and cytotoxic effects as well as repair potential using Spodoptera litura (Fabricius) as a model. Different endophytic fungi were isolated and tested for their insecticidal potential against S. litura. Among the tested endophytic fungi maximum mortality against S. litura was exhibited by S...
March 16, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29534962/barbaloin-loaded-polydopamine-polylactide-tpgs-pla-tpgs-nanoparticles-against-gastric-cancer-as-a-targeted-drug-delivery-system-studies-in-vitro-and-in-vivo
#8
Yi-Ran Wang, Shi-Yan Yang, Guang-Xia Chen, Ping Wei
Gastric cancer is the third leading cause of cancer-associated death worldwide. Although a decrease in its incidence is observed, gastric cancer still poses a major clinical challenge due to poor prognosis and limited treatments. Barbaloin (BBL) is a main medicinal composition of the Chinese traditional medicine aloe vera. BBL has various bioactivities, including anti-oxidant, anti-inflammatory and anti-tumor properties. Polydopamine (pD)-based surface modification is easy to functionalize polymeric nanoparticles (NPs) surfaces with ligands and/or additional polymeric layers...
March 20, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29526242/traditional-and-modern-aspects-of-hemorrhoid-treatment-in-iran-a-review
#9
REVIEW
Sahar Dehdari, Homa Hajimehdipoor, Somayeh Esmaeili, Rasool Choopani, Seyed Alireza Mortazavi
Hemorrhoidal disease is a prevalent anorectal condition which is generally not managed well with current pharmacologic interventions. However, in Iranian traditional medicine (ITM) there are numerous plants with hemorrhoid-healing properties. The present research assembled plants with hemorrhoid-healing properties in ITM; their related pharmacological effects, phytochemical constituents and mechanisms of action in the modern medicine were also gathered. For this purpose, leading ITM textbooks were searched for plants with hemorrhoid-healing effects...
March 2018: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29525623/starch-nanoparticle-as-a-vitamin-e-tpgs-carrier-loaded-in-silk-fibroin-poly-vinyl-alcohol-aloe-vera-nanofibrous-dressing
#10
Shadi Alsadat Kheradvar, Jhamak Nourmohammadi, Hadi Tabesh, Behnam Bagheri
Core-sheath nanofibrous mat as a new vitamin E (VE) delivery system based on silk fibroin (SF)/poly(vinyl alcohol) (PVA)/aloe vera (AV) was successfully prepared by the electrospinning method. Initially, VE-loaded starch nanoparticles were produced and then incorporated into the best beadless SF-PVA-AV nanofibers. The successful loading of VE in starch nanoparticles was proved by Fourier-transform infrared spectroscopy. The scanning electron microscopy and transmission electron microscopy indicated that spherical nanoparticles were successfully embedded within the nanofibers...
March 2, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29494957/polysaccharide-isolated-from-aloe-vera-gel-suppresses-ovalbumin-induced-food-allergy-through-inhibition-of-th2-immunity-in-mice
#11
Dajeong Lee, Hyuk Soon Kim, Eunju Shin, Seon-Gil Do, Chong-Kil Lee, Young Mi Kim, Min Bum Lee, Keun Young Min, Jimo Koo, Su Jeong Kim, Seung Taek Nam, Hyun Woo Kim, Young Hwan Park, Wahn Soo Choi
An allergic reaction occurs when the immune system overreacts to harmless substance called allergen that gains access to the body. Food allergy is a hypersensitive immune reaction to food proteins and the number of patients with food allergy has recently increased. Aloe Vera is used for wellness and medicinal purposes. In particular, Aloe vera has been reported to enhance immunity. However, the effect of Aloe vera on food allergy is not yet known. In this study, we investigated the effects of processed Aloe vera gel (PAG) containing low molecular weight Aloe polysaccharide (AP) on ovalbumin (OVA)-induced food allergy in mice...
May 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29453524/a-nonsteroidal-novel-formulation-targeting-inflammatory-and-pruritus-related-mediators-modulates-experimental-allergic-contact-dermatitis
#12
William C Gordon, Virginia García López, Surjyadipta Bhattacharjee, David Rodríguez Gil, Javier Alcover Díaz, Fernando Pineda de la Losa, Ricardo Palacios Peláez, Concha Tiana Ferrer, Gabriela Silvina Bacchini, Bokkyoo Jun, Hélène Varoqui, Nicolas G Bazan
INTRODUCTION: A major clinical challenge in treating allergic contact dermatitis (ACD) is that the first line of treatment is based on the use of corticosteroids. In this study, we aimed to develop a formulation that is devoid of steroids. METHODS: We used mouse ears treated with dinitrofluorobenzene (DNFB) to induce ACD. The efficacy of the test formulation to ameliorate and to prevent induced ACD was determined. RESULTS: To treat this experimentally induced ACD, we developed a formulation containing BIPxine (a mixture of Rosa moschata and Croton lechleri (antioxidants) and Aloe vera and D-panthenol (moisturizers), and hydroglycolic solutions of disodium cromoglycate...
February 16, 2018: Dermatology and Therapy
https://www.readbyqxmd.com/read/29450779/effects-of-growth-agents-and-mercury-on-several-herbs
#13
Zhongchuang Liu, Li-Ao Wang, Shimin Ding, Yuehan Li
The paper discussed the effects of growth agents and mercury on the growth of four herb species subjected to a pot experiment: Aloe vera, Setcreasea purpurea, Chlorophytum comosum, and Oxalis corniculata. We determined the height and biomass production of selected plants treated with different growth agents and different concentrations of mercury solutions. We evaluated the relative growth rate (RGR) of the experimental plants. The aim of the study was to explore potential novel solutions to the shortcoming of the low speed of phytoremediation...
February 15, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29412224/therapeutic-effect-of-aloe-vera-and-silver-nanoparticles-on-acid-induced-oral-ulcer-in-gamma-irradiated-mice
#14
Ahmed Ibrahim El-Batal, Salwa Farid Ahmed
Radiation combined injury, a life-threatening condition, has higher mortality than simple radiation injury. The aim of the present study was to analyze the efficiency of Aloe vera and silver nanoparticles in improving the healing of ulcerated oral mucosa after irradiation. Thirty male Albino mice were divided into five groups: control, radiation, Aloe vera (AV), silver nanoparticles (NS), and AV+NS. The mice were exposed to whole body 6Gy gamma-radiation. After one hour, 20% acetic acid was injected into the submucosal layer of the lower lip for ulcer induction...
February 5, 2018: Brazilian Oral Research
https://www.readbyqxmd.com/read/29380661/evaluation-of-wound-healing-effect-of-alginate-films-containin-g-aloe-vera-aloe-barbadensis-miller-gel
#15
Adriana Y Koga, Airton V Pereira, Leandro C Lipinski, Marcia Rp Oliveira
A new alginate dressing with Aloe vera gel was developed and used to study its cutaneous healing effect in vivo by surgical wounds in Wistar rats. The aloe-alginate film was characterized by Fourier-transform infrared spectroscopy, mechanical properties, scanning electron microscopy, hydration rate, and calcium release. The aloe-alginate film demonstrated desirable physical and mechanical characteristics for wound dressing application. The animals were divided in three groups (n = 20): gauze bandage, alginate film, and aloe-alginate film...
January 1, 2018: Journal of Biomaterials Applications
https://www.readbyqxmd.com/read/29379804/effects-of-aloe-vera-and-chitosan-nanoparticle-thin-film-membranes-on-wound-healing-in-full-thickness-infected-wounds-with-methicillin-resistant-staphylococcus-aureus
#16
Reza Ranjbar, Alireza Yousefi
Objective: To assess effect of Aleo vera with chitosan nanoparticle biofilm on wound healing in full thickness infected wounds with antibiotic resistant gram positive bacteria. Method: Thirty rats were randomized into five groups of six rats each. Group I: Animals with uninfected wounds treated with 0.9% saline solution. Group II: Animals with infected wounds treated with saline. Group III: Animals with infected wounds were dressed with chitosan nanoparticle thin-film membranes...
January 2018: Bulletin of Emergency and Trauma
https://www.readbyqxmd.com/read/29377147/the-influence-of-aloe-vera-gel-incorporation-on-the-physicochemical-and-mechanical-properties-of-banana-starch-chitosan-edible-films
#17
Magda I Pinzon, Omar R Garcia, Cristian C Villa
BACKGROUND: Aloe vera (AV) gel is a promising material in food conservation, given its widely reported antimicrobial and antioxidant activity; however, its application in the formation of edible films and coatings has been small due its low film forming capability. The aim of this study was to investigate the physicochemical properties of film forming solutions and films prepared using unriped banana starch-chitosan and AV Gel at different AV Gel concentration. RESULTS: Our results showed that AV gel considerably affects the rheological and optical properties of the edible coatings, mainly due to increased amounts of solids brought by the AV gel...
January 27, 2018: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29369521/brief-challenges-on-medicinal-plants-an-eye-opening-look-at-ageing-related-disorders
#18
Geir Bjørklund, Maryam Dadar, Natália Martins, Salvatore Chirumbolo, Bey Hing Goh, Kateryna Smetanina, Roman Lysiuk
Several studies have reported that nature-derived antioxidants may prevent free radicals over-production and therefore control the onset and prevent the exacerbation of different kinds of diseases caused by oxidative stress and redox-derived stressors, including ageing, fundamentally by suppressing the oxidative byproducts-mediated degradation. Naturally derived antioxidants exert their anti-ageing action via a panoply of signalling systems, many of which engaging reactive oxygen (ROS) and nitrogen (RNS) species scavenging, with the Nrf2/Keap1-ARE system and improving the many survival genes and functions (such as the pathway mTOR/Foxo/SIRT1) able to slow cellular senescence...
January 25, 2018: Basic & Clinical Pharmacology & Toxicology
https://www.readbyqxmd.com/read/29337103/green-options-for-imparting-antibacterial-functionality-to-cotton-fabrics
#19
Nabil A Ibrahim, Nahed A Abd El-Ghany, Basma M Eid, Eman M Mabrouk
This study demonstrated that antibacterial cellulosic textiles can be fabricated in eco-friendly manner by grafting of monochlorotriazinyl β-cyclodextin (MCT-βCD) onto knitted and woven cotton fabrics followed by post-loading of any of the green active ingredients namely Rosemary oil, Lavender oil, Clove oil, Cinnamon oil, Aloe vera gel, Vanillin, Ag-ions, Natural Yellow 7 and Natural Red 25 dyes into the hydrophobic cavities of grafted β-CD moieties. Some of the grafted, post-loaded fabric samples were characterized by FTIR, SEM, and EDS analysis...
May 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29336265/efficacy-of-aloe-vera-plantago-major-gel-in-diabetic-foot-ulcer-a-randomized-double-blind-clinical-trial
#20
Younes Najafian, Zahra Mazloum, Mona Najaf Najafi, Shokouhsadat Hamedi, Marjan Mahjour, Zohre Feyzabadi
BACKGROUND: Diabetic foot ulcer (DFU) is one of the most common complications of diabetic patients. Mostly, non-healing DFU leads to infection, gangrene, amputation and even death. High costs and poor healing of the wounds need a new treatment such as alternative medicine. So, the aim of this study was to evaluate the efficacy of Aloe vera/ Plantago major gel (Plantavera gel) in healing of DFU. METHODS: Forty patients with DFU enrolled in a double-blind randomized clinical trial...
January 14, 2018: Current Drug Discovery Technologies
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