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cod liver oil

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https://www.readbyqxmd.com/read/29755576/cold-pressed-minke-whale-oil-reduces-circulating-ldl-vldl-cholesterol-lipid-oxidation-and-atherogenesis-in-apolipoprotein-e-deficient-mice-fed-a-western-type-diet-for-13-weeks
#1
Mari Johannessen Walquist, Svein Kristian Stormo, Bjarne Østerud, Edel O Elvevoll, Karl-Erik Eilertsen
Background: Long-chain n3-polyunsaturated fatty acids (LC n3-PUFA) are well known for their anti-inflammatory activity and their impact on cardiovascular disease. Cold-pressed whale oil (CWO) has half the amount of LC n3-PUFA compared to cod liver oil (CLO). Still, there has been observed more pronounced beneficial effects on cardiovascular disease markers from intake of CWO compared to intake of CLO in human intervention studies. Extracts from CWO deprived of fatty acids have also been shown to display antioxidative and anti-inflammatory effects in vitro...
2018: Nutrition & Metabolism
https://www.readbyqxmd.com/read/29722838/vitamin-a-and-d-intake-in-pregnancy-infant-supplementation-and-asthma-development-the-norwegian-mother-and-child-cohort
#2
Christine L Parr, Maria C Magnus, Øystein Karlstad, Kristin Holvik, Nicolai A Lund-Blix, Margareta Haugen, Christian M Page, Per Nafstad, Per M Ueland, Stephanie J London, Siri E Håberg, Wenche Nystad
Background: Western diets may provide excess vitamin A, which is potentially toxic and could adversely affect respiratory health and counteract benefits from vitamin D. Objective: The aim of this study was to examine child asthma at age 7 y in relation to maternal intake of vitamins A and D during pregnancy, infant supplementation with these vitamins, and their potential interaction. Design: We studied 61,676 school-age children (born during 2002-2007) from the Norwegian Mother and Child Cohort with data on maternal total (food and supplement) nutrient intake in pregnancy (food-frequency questionnaire validated against biomarkers) and infant supplement use at age 6 mo (n = 54,142 children)...
May 1, 2018: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29501159/a-novel-strategy-for-discriminating-marine-oils-by-using-the-positional-distribution-sn-1-sn-2-sn-3-of-omega-3-polyunsaturated-fatty-acids-in-triacylglycerols
#3
Pedro Araujo, Ephrem Tilahun, Yingxu Zeng
A novel strategy for discriminating genuine and adulterated marine oils is proposed. The strategy consists of i) determining the stereospecific distribution (sn-1, sn-2 and sn-3) of omega 3 polyunsaturated fatty acids (ω-3 PUFA) on the backbone of triacylglycerols by using liquid chromatography tandem mass spectrometry; ii) transforming the qualitative stereospecific information into quantitative data by means of a novel strategy; iii) analyzing the transformed data by principal component analysis. The proposed strategy was tested on pure oils (seal, salmon, cod liver, sandeel, blue whiting, herring), a mixture of blue whiting, herring, sandeel and Norway pout and some intentionally adulterated oils...
May 15, 2018: Talanta
https://www.readbyqxmd.com/read/29484348/associations-between-proportion-of-plasma-phospholipid-fatty-acids-depressive-symptoms-and-major-depressive-disorder-cross-sectional-analyses-from-the-ages-reykjavik-study
#4
C M Imai, T I Halldorsson, T Aspelund, G Eiriksdottir, L J Launer, I Thorsdottir, T B Harris, V Gudnason, I A Brouwer, I Gunnarsdottir
BACKGROUND: Deficits in n-3 fatty acids may be associated with depression. However, data are scarce from older adults who are at greater risk of poor dietary intake and of developing depression. OBJECTIVE: To investigate proportion of plasma phospholipid fatty acids with respect to depressive symptoms and major depressive disorder in community dwelling older adults. METHODS: Cross-sectional analyses of 1571 participants in the Age, Gene/Environment Susceptibility (AGES)-Reykjavik Study aged 67-93 years...
2018: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/29211087/correction-formation-of-reactive-aldehydes-mda-hhe-hne-during-the-digestion-of-cod-liver-oil-comparison-of-human-and-porcine-in-vitro-digestion-models
#5
Cecilia Tullberg, Karin Larsson, Nils-Gunnar Carlsson, Irene Comi, Nathalie Scheers, Gerd Vegarud, Ingrid Undeland
Correction for 'Formation of reactive aldehydes (MDA, HHE, HNE) during the digestion of cod liver oil: comparison of human and porcine in vitro digestion models' by Cecilia Tullberg et al., Food Funct., 2016, 7, 1401-1412.
December 13, 2017: Food & Function
https://www.readbyqxmd.com/read/29166929/prevalence-of-dietary-supplement-use-and-associated-factors-among-female-college-students-in-saudi-arabia
#6
Hanan Alfawaz, Nasiruddin Khan, Aziza Alfaifi, Fatima M Shahrani, Huda M Al Tameem, Seetah F Al Otaibi, Weaam I Abudigin, Mohammad S Al-Shayaa, Saad A Al-Ghanim, Nasser M Al-Daghri
BACKGROUND: The economic boom in Saudi Arabia indirectly prompted the use of dietary supplements in the last two decades. Our aim is to investigate the prevalence of dietary supplement use and its association with sociodemographic/lifestyle characteristics among Saudi female students. METHODS: In this cross-sectional study, 534 female participants (≥19 years of age) completed a self-administered questionnaire that include sociodemographic and lifestyle characteristics, perceived health status, dietary supplement use, general awareness, attitudes and behavior...
November 22, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/29153102/stability-of-compounded-trilostane-suspension-in-cod-liver-oil
#7
Jesse Crosby, Stacy Brown
Trilostane is a synthetic steroid analog used to treat canine hyperadrenocorticism. For small dogs, the dose found in commercially available dosage forms of trilostane is sometimes too high. Compounding trilostane in a liquid diluent provides an option for more precise dosing and adjustments, and can be easier to administer, versus a tablet or capsule. Trilostane suspends well in cod liver oil, which is generally palatable to dogs. The stability of a compounded trilostane suspension in cod liver oil stored at room temperature was investigated for 90 days...
October 2017: Veterinary Journal
https://www.readbyqxmd.com/read/29118465/antioxidant-and-anti-inflammatory-activities-in-extracts-from-minke-whale-balaenoptera-acutorostrata-blubber
#8
Mari Johannessen Walquist, Svein Kristian Stormo, Ida-Johanne Jensen, Bjarne Østerud, Karl-Erik Eilertsen
Intake of long-chain omega-3 polyunsaturated fatty acids (LC-n3-PUFA) is commonly recognized to reduce cardiovascular disease (CVD). In previous studies, cold-pressed whale oil (CWO) and cod liver oil (CLO) were given as a dietary supplement to healthy volunteers. Even though CWO contains less than half the amount of LC-n3-PUFA of CLO, CWO supplement resulted in beneficial effects on anti-inflammatory and CVD risk markers compared to CLO. In the present study, we prepared virtually lipid-free extracts from CWO and CLO and evaluated the antioxidative capacity (AOC) and anti-inflammatory effects...
2017: Mediators of Inflammation
https://www.readbyqxmd.com/read/29113061/effects-of-marine-oils-digested-with-human-fluids-on-cellular-viability-and-stress-protein-expression-in-human-intestinal-caco-2-cells
#9
Cecilia Tullberg, Gerd Vegarud, Ingrid Undeland, Nathalie Scheers
In vitro digestion of marine oils has been reported to promote lipid oxidation, including the formation of reactive aldehydes (e.g., malondialdehyde (MDA) and 4-hydroxy-2-hexenal (HHE)). We aimed to investigate if human in vitro digestion of supplemental levels of oils from algae, cod liver, and krill, in addition to pure MDA and HHE, affect intestinal Caco-2 cell survival and oxidative stress. Cell viability was not significantly affected by the digests of marine oils or by pure MDA and HHE (0-90 μM). Cellular levels of HSP-70, a chaperone involved in the prevention of stress-induced protein unfolding was significantly decreased (14%, 28%, and 14% of control for algae, cod and krill oil, respectively; p ≤ 0...
November 4, 2017: Nutrients
https://www.readbyqxmd.com/read/29048366/lipase-catalyzed-transesterification-of-egg-yolk-phophatidylcholine-with-concentrate-of-n-3-polyunsaturated-fatty-acids-from-cod-liver-oil
#10
Anna Chojnacka, Witold Gładkowski, Aleksandra Grudniewska
Phospholipids containing PUFAs are important vehicles for their delivering to the targeted tissues. In our research project we established enzymatic methods for the enrichment of natural egg-yolk PC with n-3 PUFAs. Instead of synthetic PUFA ethyl esters, the new strategy was developed using polyunsaturated fatty acids enriched fraction (PUFA-EF) from cod liver oil as the natural acyl donors. PUFA-EF was produced by urea-complexation and contained 86.9% PUFA including 8.5% stearidonic acid (SDA; 18:4(n-3)), 26...
October 19, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29030414/longitudinal-associations-between-marine-omega-3-supplement-users-and-coronary-heart-disease-in-a-uk-population-based-cohort
#11
Marleen A H Lentjes, Ruth H Keogh, Ailsa A Welch, Angela A Mulligan, Robert N Luben, Nicholas J Wareham, Kay-Tee Khaw
OBJECTIVES: Assess the association between marine omega-3 polyunsaturated fatty acid (n-3 PUFA) intake from supplements, mainly cod liver oil, and coronary heart disease (CHD) mortality. DESIGN: Prospective cohort study, with three exposure measurements over 22 years. SETTING: Norfolk-based European Prospective Investigation into Cancer (EPIC-Norfolk, UK). PARTICIPANTS: 22 035 men and women from the general population, 39-79 years at recruitment...
October 13, 2017: BMJ Open
https://www.readbyqxmd.com/read/28763949/physical-and-oxidative-stability-of-fish-oil-in-water-emulsions-fortified-with-enzymatic-hydrolysates-from-common-carp-cyprinus-carpio-roe
#12
Sakhi Ghelichi, Ann-Dorit Moltke Sørensen, Pedro J García-Moreno, Mona Hajfathalian, Charlotte Jacobsen
Physical and oxidative stability of 5% (by weight) cod liver oil-in-water emulsions fortified with common carp (C. carpio) roe protein hydrolysate (CRPH) were examined. CRPH was obtained by enzymatic hydrolysis of discarded roe by using Alcalase 2.4L for 30, 60, 90, and 120min to yield different degrees of hydrolysis (DH). All the hydrolysates showed in vitro antioxidant activity in terms of radical scavenging and chelating properties. CRPH-containing emulsions had significantly smaller droplets than control (p<0...
December 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28756294/vitamin-d-cod-liver-oil-sunshine-and-phototherapy-safe-effective-and-forgotten-tools-for-treating-and-curing-tuberculosis-infections-a-comprehensive-review
#13
REVIEW
Patrick J McCullough, Douglas S Lehrer
Tuberculosis remains an epidemic throughout the world, with over 2 billion people, or more than one third of the world's population, infected with TB. In 2015, there were an estimated 10.4 million new cases of tuberculosis, and 1.8 million deaths, making TB one of the top ten causes of death worldwide. Approximately 95% of new TB cases occur in developing countries, where the costs of treatment force many patients and their families into poverty. The United Nations and the World Health Organization are working to end this global epidemic...
March 2018: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/28571624/reprint-of-cyp1a-protein-expression-and-catalytic-activity-in-double-crested-cormorants-experimentally-exposed-to-deepwater-horizon-mississippi-canyon-252-oil
#14
Courtney R Alexander, Michael J Hooper, Dave Cacela, Kim D Smelker, Caleshia S Calvin, Karen M Dean, Steve J Bursian, Fred L Cunningham, Katie C Hanson-Dorr, Katherine E Horak, John P Isanhart, Jane Link, Susan A Shriner, Céline A J Godard-Codding
Double-crested cormorants (Phalacrocorax auritus, DCCO) were orally exposed to Deepwater Horizon Mississippi Canyon 252 (DWH) oil to investigate oil-induced toxicological impacts. Livers were collected for multiple analyses including cytochrome P4501A (CYP1A) enzymatic activity and protein expression. CYP1A enzymatic activity was measured by alkoxyresorufin O-dealkylase (AROD) assays. Activities specific to the O-dealkylation of four resorufin ethers are reported: benzyloxyresorufin O-debenzylase (BROD), ethoxyresorufin O-deethylase (EROD), methoxyresorufin O-demethylase (MROD), and pentoxyresorufin O-depentylase (PROD)...
December 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28492305/monitoring-interfacial-lipid-oxidation-in-oil-in-water-emulsions-using-spatially-resolved-optical-techniques
#15
Chiranjib Banerjee, Michael Westberg, Thomas Breitenbach, Mikkel Bregnhøj, Peter R Ogilby
The oxidation of lipids is an important phenomenon with ramifications for disciplines that range from food science to cell biology. The development and characterization of tools and techniques to monitor lipid oxidation are thus relevant. Of particular significance in this regard are tools that facilitate the study of oxidations at interfaces in heterogeneous samples (e.g., oil-in-water emulsions, cell membranes). In this article, we establish a proof-of-principle for methods to initiate and then monitor such oxidations with high spatial resolution...
June 6, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28490135/polyunsaturated-lipids-and-vitamin-a-oxidation-during-cod-liver-oil-in-vitro-gastrointestinal-digestion-antioxidant-effect-of-added-bht
#16
Bárbara Nieva-Echevarría, Encarnación Goicoechea, María D Guillén
The extent of cod liver oil hydrolysis and oxidation during in vitro gastrointestinal digestion was investigated by Proton Nuclear Magnetic Resonance ((1)H NMR) and Solid Phase Microextraction-Gas Chromatography/Mass Spectrometry (SPME-GC/MS). These techniques evidenced the degradation of polyunsaturated ω-3 and ω-6 lipids and, for the first time, that of vitamin A, naturally present in cod liver oil. Cis,trans-conjugated dienes associated with hydroperoxides, as well as monoepoxides, cis,trans-2,4-alkadienals, 4-hydroperoxy- and 4-hydroxy-2-alkenals, and several vitamin A derived metabolites were generated...
October 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28390242/cyp1a-protein-expression-and-catalytic-activity-in-double-crested-cormorants-experimentally-exposed-to-deepwater-horizon-mississippi-canyon-252-oil
#17
Courtney R Alexander, Michael J Hooper, Dave Cacela, Kim D Smelker, Caleshia S Calvin, Karen M Dean, Steve J Bursian, Fred L Cunningham, Katie C Hanson-Dorr, Katherine E Horak, John P Isanhart, Jane Link, Susan A Shriner, Céline A J Godard-Codding
Double-crested cormorants (Phalacrocorax auritus, DCCO) were orally exposed to Deepwater Horizon Mississippi Canyon 252 (DWH) oil to investigate oil-induced toxicological impacts. Livers were collected for multiple analyses including cytochrome P4501A (CYP1A) enzymatic activity and protein expression. CYP1A enzymatic activity was measured by alkoxyresorufin O-dealkylase (AROD) assays. Activities specific to the O-dealkylation of four resorufin ethers are reported: benzyloxyresorufin O-debenzylase (BROD), ethoxyresorufin O-deethylase (EROD), methoxyresorufin O-demethylase (MROD), and pentoxyresorufin O-depentylase (PROD)...
April 5, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/27892584/a-short-history-of-phototherapy-vitamin-d-and-skin-disease
#18
Paul Jarrett, Robert Scragg
The earliest record between sun exposure and skin disease goes back five millennia to the ancient Egyptians. The modern scientific era of medical light therapy and skin diseases started in 1877 when Downs and Blunt reported that exposure to light inhibited fungal growth in test tubes. Continuing research generated a growing medical interest in the potential the effects of light to treat and cure skin diseases considered as parasitic. This culminated in the awarding of the 1903 Nobel Prize in Medicine to Niels Finsen for his pioneering work showing that light could successfully treat cutaneous mycobacterium tuberculosis (lupus vulgaris), a disfiguring disorder common at the time...
March 16, 2017: Photochemical & Photobiological Sciences
https://www.readbyqxmd.com/read/27630989/lack-of-effects-of-a-single-high-fat-meal-enriched-with-vegetable-n-3-or-a-combination-of-vegetable-and-marine-n-3-fatty-acids-on-intestinal-peptide-release-and-adipokines-in-healthy-female-subjects
#19
Ingunn Narverud, Mari C W Myhrstad, Karl-Heinz Herzig, Toni Karhu, Tuva B Dahl, Bente Halvorsen, Stine M Ulven, Kirsten B Holven
Peptides released from the small intestine and colon regulate short-term food intake by suppressing appetite and inducing satiety. Intake of marine omega-3 (n-3) fatty acids (FAs) from fish and fish oils is associated with beneficial health effects, whereas the relation between intake of the vegetable n-3 fatty acid α-linolenic acid and diseases is less clear. The aim of the present study was to investigate the postprandial effects of a single high-fat meal enriched with vegetable n-3 or a combination of vegetable and marine n-3 FAs with their different unsaturated fatty acid composition on intestinal peptide release and the adipose tissue...
2016: Frontiers in Nutrition
https://www.readbyqxmd.com/read/27534845/plasma-phospholipid-pentadecanoic-acid-epa-and-dha-and-the-frequency-of-dairy-and-fish-product-intake-in-young-children
#20
Nicolai A Lund-Blix, Kjersti S Rønningen, Håkon Bøås, German Tapia, Lene F Andersen
BACKGROUND: There is a lack of studies comparing dietary assessment methods with the biomarkers of fatty acids in children. OBJECTIVE: The objective was to evaluate the suitability of a food frequency questionnaire (FFQ) to rank young children according to their intake of dairy and fish products by comparing food frequency estimates to the plasma phospholipid fatty acids pentadecanoic acid, eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA). DESIGN: Cross-sectional data for the present study were derived from the prospective cohort 'Environmental Triggers of Type 1 Diabetes Study'...
2016: Food & Nutrition Research
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