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IOTA ultrasound

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https://www.readbyqxmd.com/read/29236181/ultrasound-based-logistic-regression-model-lr2-versus-magnetic-resonance-imaging-for-discriminating-between-benign-and-malignant-adnexal-masses-a-prospective-study
#1
Kanane Shimada, Koji Matsumoto, Takashi Mimura, Tetsuya Ishikawa, Jiro Munechika, Yoshimitsu Ohgiya, Miki Kushima, Yusuke Hirose, Yuka Asami, Chiaki Iitsuka, Shingo Miyamoto, Mamiko Onuki, Hajime Tsunoda, Ryu Matsuoka, Kiyotake Ichizuka, Akihiko Sekizawa
BACKGROUND: The diagnostic performances of the International Ovarian Tumor Analysis (IOTA) ultrasound-based logistic regression model (LR2) and magnetic resonance imaging (MRI) in discriminating between benign and malignant adnexal masses have not been directly compared in a single study. METHODS: Using the IOTA LR2 model and subjective interpretation of MRI findings by experienced radiologists, 265 consecutive patients with adnexal masses were preoperatively evaluated in two hospitals between February 2014 and December 2015...
December 13, 2017: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29172273/sonographic-diagnosis-of-tubal-cancer-with-iota-simple-rules-plus-pattern-recognition
#2
Theera Tongsong, Chanane Wanapirak, Charuwan Tantipalakorn, Dangcheewan Tinnangwattana
Objective: To evaluate diagnostic performance of IOTA simple rules plus pattern recognition in predicting tubal cancer. Methods: Secondary analysis was performed on prospective database of our IOTA project. The patients recruited in the project were those who were scheduled for pelvic surgery due to adnexal masses. The patients underwent ultrasound examinations within 24 hours before surgery. On ultrasound examination, the masses were evaluated using the well-established IOTA simple rules plus pattern recognition (sausage-shaped appearance, incomplete septum, visible ipsilateral ovaries) to predict tubal cancer...
November 26, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/29119698/differences-in-the-ultrasound-features-of-papillations-in-unilocular-solid-adnexal-cysts-a-retrospective-international-multicenter-study
#3
Chiara Landolfo, Lil Valentin, Dorella Franchi, Caroline Van Holsbeke, Robert Fruscio, Wouter Froyman, Povilas Sladkevicius, Jeroen Kaijser, Lieveke Ameye, Tom Bourne, Luca Savelli, An Coosemans, Antonia Testa, Dirk Timmerman
OBJECTIVES: The aim is to determine if there are any ultrasound features of papillations or of the cyst wall that can discriminate between benign and malignant unilocular-solid cysts with papillations but no other solid components. METHODS: Patients with an adnexal lesion described at ultrasonography as unilocular-solid with papillations but no other solid components were identified from the International Ovarian Tumor Analysis (IOTA) database derived from seven ultrasound centers...
November 8, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28976616/a-prospective-evaluation-of-the-iota-logistic-regression-models-lr1-and-lr2-in-comparison-to-subjective-pattern-recognition-for-the-diagnosis-of-ovarian-cancer-in-the-outpatient-setting
#4
Natalie Nunes, Gareth Ambler, Xulin Foo, Martin Widschwendter, Davor Jurkovic
OBJECTIVES: To determine whether IOTA diagnostic models developed for pre-operative diagnosis of ovarian cancer could also be used to differentiate between benign and malignant adnexal tumours in the population of women attending gynaecology outpatient clinics. METHODS: All women referred to our outpatient clinic were first examined by a Level II ultrasound operator. In those diagnosed with adnexal tumours the IOTA LR1/2 protocol was used to evaluate the masses...
October 4, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28969237/evaluation-of-iota-simple-ultrasound-rules-to-distinguish-benign-and-malignant-ovarian-tumours
#5
Sugandha Garg, Amarjit Kaur, Jaswinder Kaur Mohi, Preet Kanwal Sibia, Navkiran Kaur
INTRODUCTION: IOTA stands for International Ovarian Tumour Analysis group. Ovarian cancer is one of the common cancers in women and is diagnosed at later stage in majority. The limiting factor for early diagnosis is lack of standardized terms and procedures in gynaecological sonography. Introduction of IOTA rules has provided some consistency in defining morphological features of ovarian masses through a standardized examination technique. AIM: To evaluate the efficacy of IOTA simple ultrasound rules in distinguishing benign and malignant ovarian tumours and establishing their use as a tool in early diagnosis of ovarian malignancy...
August 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28834973/simple-rules-not-so-simple-the-use-of-international-ovarian-tumor-analysis-iota-terminology-and-simple-rules-in-inexperienced-hands-in-a-prospective-multicenter-cohort-study
#6
Evelyne Meys, Iris Rutten, Roy Kruitwagen, Brigitte Slangen, Sandrina Lambrechts, Helen Mertens, Ernst Nolting, Dieuwke Boskamp, Toon Van Gorp
Objectives To analyze how well untrained examiners - without experience in the use of International Ovarian Tumor Analysis (IOTA) terminology or simple ultrasound-based rules (simple rules) - are able to apply IOTA terminology and simple rules and to assess the level of agreement between non-experts and an expert. Methods This prospective multicenter cohort study enrolled women with ovarian masses. Ultrasound was performed by non-expert examiners and an expert. Ultrasound features were recorded using IOTA nomenclature, and used for classifying the mass by simple rules...
August 23, 2017: Ultraschall in der Medizin
https://www.readbyqxmd.com/read/28735703/ovarian-mass-differentiating-benign-from-malignant-the-value-of-the-international-ovarian-tumor-analysis-ultrasound-rules
#7
Jacques S Abramowicz, Dirk Timmerman
Ovarian cancer, the fifth most common cause of cancer death among women, has the highest mortality rate of all gynecologic cancers. General survival rate is <50% but can reach 90% if disease is detected early. Ultrasound is presently the best modality to differentiate between benign and malignant status. The patient with a malignant mass should be referred to an oncology surgeon since results have been shown to be superior to treatment by a specialist. Several ultrasound-based scoring systems exist for assessing the risk of an ovarian tumor to be malignant...
December 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28574444/validation-of-the-performance-of-international-ovarian-tumor-analysis-iota-methods-in-the-diagnosis-of-early-stage-ovarian-cancer-in-a-non-screening-population
#8
Wouter Froyman, Laure Wynants, Chiara Landolfo, Tom Bourne, Lil Valentin, Antonia Testa, Povilas Sladkevicius, Dorella Franchi, Daniela Fischerova, Luca Savelli, Ben Van Calster, Dirk Timmerman
BACKGROUND: The aim of this study was to assess and compare the performance of different ultrasound-based International Ovarian Tumor Analysis (IOTA) strategies and subjective assessment for the diagnosis of early stage ovarian malignancy. METHODS: This is a secondary analysis of a prospective multicenter cross-sectional diagnostic accuracy study that included 1653 patients recruited at 18 centers from 2009 to 2012. All patients underwent standardized transvaginal ultrasonography by experienced ultrasound investigators...
June 2, 2017: Diagnostics
https://www.readbyqxmd.com/read/28512173/clinical-utility-of-risk-models-to-refer-patients-with-adnexal-masses-to-specialized-oncology-care-multicenter-external-validation-using-decision-curve-analysis
#9
Laure Wynants, Dirk Timmerman, Jan Y Verbakel, Antonia Testa, Luca Savelli, Daniela Fischerova, Dorella Franchi, Caroline Van Holsbeke, Elisabeth Epstein, Wouter Froyman, Stefano Guerriero, Alberto Rossi, Robert Fruscio, Francesco Pg Leone, Tom Bourne, Lil Valentin, Ben Van Calster
Purpose: To evaluate the utility of preoperative diagnostic models for ovarian cancer based on ultrasound and/or biomarkers for referring patients to specialized oncology care. The investigated models were RMI, ROMA, and 3 models from the International Ovarian Tumor Analysis (IOTA) group [LR2, ADNEX, and the Simple Rules risk score (SRRisk)].Experimental Design: A secondary analysis of prospectively collected data from 2 cross-sectional cohort studies was performed to externally validate diagnostic models. A total of 2,763 patients (2,403 in dataset 1 and 360 in dataset 2) from 18 centers (11 oncology centers and 7 nononcology hospitals) in 6 countries participated...
May 16, 2017: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/28288666/reliability-of-preoperative-evaluation-of-postmenopausal-ovarian-tumors
#10
Riikka Johanna Niemi, Sami Kristian Saarelainen, Tiina Hannele Luukkaala, Johanna Unelma Mäenpää
BACKGROUND: Preoperative evaluation of ovarian tumors is challenging. This study was undertaken to evaluate the performance of conventional two-dimensional (2D) ultrasound and CA125 in predicting malignant or benign nature of pelvic masses, and to investigate if three-dimensional power Doppler (3DPD) ultrasound provides any added value. Ninety-six postmenopausal and four perimenopausal women with supposed ovarian tumors were examined by standardized 2D and 3DPD ultrasounds preoperatively...
March 14, 2017: Journal of Ovarian Research
https://www.readbyqxmd.com/read/28004457/clinical-and-ultrasound-characteristics-of-surgically-removed-adnexal-lesions-with-largest-diameter-%C3%A2-%C3%A2-2-5%C3%A2-cm-a-pictorial-essay
#11
A Di Legge, P Pollastri, R Mancari, M Ludovisi, F Mascilini, D Franchi, D Jurkovic, M E Coccia, D Timmerman, G Scambia, A Testa, L Valentin
OBJECTIVES: To describe the ultrasound characteristics, indications for surgery and histological diagnoses of surgically removed adnexal masses with a largest diameter of ≤ 2.5 cm (very small tumors), to estimate the sensitivity and specificity of diagnosis of malignancy by subjective assessment of ultrasound images of very small tumors and to present a collection of ultrasound images of surgically removed very small tumors, with emphasis on those causing diagnostic difficulty. METHODS: Information on surgically removed adnexal tumors with a largest diameter of ≤ 2...
November 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27797247/comparison-of-effectiveness-in-differentiating-benign-from-malignant-ovarian-masses-between-iota-simple-rules-and-subjective-sonographic-assessment
#12
Theera Tongsong, Dangcheewan Tinnangwattana, Linlada Vichak-Ururote, Paponrad Tontivuthikul, Cholaros Charoenratana, Thitikarn Lerthiranwong
BACKGROUND: To compare diagnostic performance in differentiating benign from malignant ovarian masses between IOTA (the International Ovarian Tumor Analysis) simple rules and subjective sonographic assessment. MATERIALS AND METHODS: Women scheduled for elective surgery because of ovarian masses were recruited into the study and underwent ultrasound examination within 24 hours of surgery to apply the IOTA simple rules by general gynecologists and to record video clips for subjective assessment by an experienced sonographer...
2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27507231/refining-ovarian-cancer-test-accuracy-scores-rockets-protocol-for-a-prospective-longitudinal-test-accuracy-study-to-validate-new-risk-scores-in-women-with-symptoms-of-suspected-ovarian-cancer
#13
Sudha Sundar, Caroline Rick, Francis Dowling, Pui Au, Kym Snell, Nirmala Rai, Rita Champaneria, Hilary Stobart, Richard Neal, Clare Davenport, Susan Mallett, Andrew Sutton, Sean Kehoe, Dirk Timmerman, Tom Bourne, Ben Van Calster, Aleksandra Gentry-Maharaj, Usha Menon, Jon Deeks
INTRODUCTION: Ovarian cancer (OC) is associated with non-specific symptoms such as bloating, making accurate diagnosis challenging: only 1 in 3 women with OC presents through primary care referral. National Institute for Health and Care Excellence guidelines recommends sequential testing with CA125 and routine ultrasound in primary care. However, these diagnostic tests have limited sensitivity or specificity. Improving accurate triage in women with vague symptoms is likely to improve mortality by streamlining referral and care pathways...
2016: BMJ Open
https://www.readbyqxmd.com/read/27506445/ultrasound-based-iota-simple-rules-allow-accurate-malignancy-risk-estimation-for-adnexal-masses
#14
COMMENT
Juan Luis Alcázar
No abstract text is available yet for this article.
October 2016: Evidence-based Medicine
https://www.readbyqxmd.com/read/27484484/ovarian-masses-with-papillary-projections-diagnosed-and-removed-during-pregnancy-ultrasound-features-and-histological-diagnoses
#15
F Mascilini, L Savelli, M C Scifo, C Exacoustos, I Timor-Tritsch, I De Blasis, M C Moruzzi, T Pasciuto, G Scambia, L Valentin, A C Testa
OBJECTIVES: To elucidate if there are any ultrasound features that can be used to discriminate between benign and malignant cysts with papillary projections but no other solid components in pregnant women. METHODS: Thirty-four women with an ultrasound diagnosis of an ovarian cyst with papillary projections but no other solid components that had been surgically removed during pregnancy were identified from the databases of four ultrasound units. Some clinical and ultrasound information had been collected prospectively...
August 3, 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27282774/age-related-differences-in-the-sonographic-characteristics-of-endometriomas
#16
Stefano Guerriero, Ben Van Calster, Edgardo Somigliana, Silvia Ajossa, Wouter Froyman, Bavo De Cock, An Coosemans, Daniela Fischerová, Caroline Van Holsbeke, Juan Luis Alcazar, Antonia C Testa, Lil Valentin, Tom Bourne, Dirk Timmerman
STUDY QUESTION: Do sonographic characteristics of ovarian endometriomas vary with age in premenopausal women? SUMMARY ANSWER: With increasing age, multilocular cysts and cysts with papillations and other solid components become more common whereas ground glass echogenicity of cyst fluid becomes less common. WHAT IS KNOWN ALREADY: Expectant or medical management of women with endometriomas is now accepted. Therefore, the accuracy of non-invasive diagnosis of these cysts is pivotal...
August 2016: Human Reproduction
https://www.readbyqxmd.com/read/26922169/subjective-assessment-versus-ultrasound-models-to-diagnose-ovarian-cancer-a-systematic-review-and-meta-analysis
#17
REVIEW
E M J Meys, J Kaijser, R F P M Kruitwagen, B F M Slangen, B Van Calster, B Aertgeerts, J Y Verbakel, D Timmerman, T Van Gorp
INTRODUCTION: Many national guidelines concerning the management of ovarian cancer currently advocate the risk of malignancy index (RMI) to characterise ovarian pathology. However, other methods, such as subjective assessment, International Ovarian Tumour Analysis (IOTA) simple ultrasound-based rules (simple rules) and IOTA logistic regression model 2 (LR2) seem to be superior to the RMI. Our objective was to compare the diagnostic accuracy of subjective assessment, simple rules, LR2 and RMI for differentiating benign from malignant adnexal masses prior to surgery...
May 2016: European Journal of Cancer
https://www.readbyqxmd.com/read/26800772/predicting-the-risk-of-malignancy-in-adnexal-masses-based-on-the-simple-rules-from-the-international-ovarian-tumor-analysis-group
#18
MULTICENTER STUDY
Dirk Timmerman, Ben Van Calster, Antonia Testa, Luca Savelli, Daniela Fischerova, Wouter Froyman, Laure Wynants, Caroline Van Holsbeke, Elisabeth Epstein, Dorella Franchi, Jeroen Kaijser, Artur Czekierdowski, Stefano Guerriero, Robert Fruscio, Francesco P G Leone, Alberto Rossi, Chiara Landolfo, Ignace Vergote, Tom Bourne, Lil Valentin
BACKGROUND: Accurate methods to preoperatively characterize adnexal tumors are pivotal for optimal patient management. A recent metaanalysis concluded that the International Ovarian Tumor Analysis algorithms such as the Simple Rules are the best approaches to preoperatively classify adnexal masses as benign or malignant. OBJECTIVE: We sought to develop and validate a model to predict the risk of malignancy in adnexal masses using the ultrasound features in the Simple Rules...
April 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/26461961/simple-descriptors-and-simple-rules-of-the-international-ovarian-tumor-analysis-iota-group-a-prospective-study-of-combined-use-for-the-description-of-adnexal-masses
#19
Almudena Peces Rama, María Carmen Llanos Llanos, María Luisa Sánchez Ferrer, Juan Luis Alcázar Zambrano, Antonio Martínez Mendoza, Aníbal Nieto Díaz
OBJECTIVE: External validation of the IOTA group's three-step diagnostic model (Strategy 1) and comparison with assessment by an expert sonographer (Strategy 2). STUDY DESIGN: Prospective study in patients with persistent adnexal masses, in which an inexperienced sonographer performed transvaginal ultrasound applying simple descriptors (SD) and rules (SR) for classifying as benign or malignant. Any non-classifiable mass was then submitted to an expert examiner for subjective assessment (SA)...
December 2015: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/26219956/limitations-of-three-dimensional-power-doppler-angiography-in-preoperative-evaluation-of-ovarian-tumors
#20
Liliane Silvestre, Wellington P Martins, Francisco J Candido-Dos-Reis
BACKGROUND: This study describes the accuracy of three-dimensional power Doppler (3D-PD) angiography as secondary method for differential diagnosis of ovarian tumors. METHOD: Seventy-five women scheduled for surgical removal of adnexal masses were assessed by transvaginal ultrasound. Ovarian tumors were classified by IOTA simple rules and two three-dimensional blocks were recorded. In a second step analyses, a 4 cm(3) spherical sample was obtained from the highest vascularized solid area of each stored block...
July 29, 2015: Journal of Ovarian Research
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