keyword
MENU ▼
Read by QxMD icon Read
search

pilots

keyword
https://www.readbyqxmd.com/read/28931194/intracapsular-tonsillectomy-for-keratosis-pharyngeous-a-pilot-study-of-postoperative-recovery-and-surgical-efficacy
#1
Philip A Gaudreau, Eric M Gessler
Our objective was to perform a pilot study comparing intracapsular radiofrequency ablation tonsillectomy with subcapsular tonsillectomy in adult patients with keratosis pharyngeous. Patients diagnosed with keratosis pharyngeous between December 2010 and February 2013 were randomized to undergo either intracapsular or subcapsular tonsillectomy using radiofrequency ablation. Postoperative pain scores and amount of pain medication taken were recorded for 2 weeks. A 6-month follow-up questionnaire was used to assess efficacy of the procedure...
September 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/28931089/advanced-glycation-end-products-dietary-restriction-effects-on-bacterial-gut-microbiota-in-peritoneal-dialysis-patients-a-randomized-open-label-controlled-trial
#2
Rabi Yacoub, Melinda Nugent, Weijin Cai, Girish N Nadkarni, Lee D Chaves, Sham Abyad, Amanda M Honan, Shruthi A Thomas, Wei Zheng, Sujith A Valiyaparambil, Mark A Bryniarski, Yijun Sun, Michael Buck, Robert J Genco, Richard J Quigg, John C He, Jaime Uribarri
The modern Western diet is rich in advanced glycation end products (AGEs). We have previously shown an association between dietary AGEs and markers of inflammation and oxidative stress in a population of end stage renal disease (ESRD) patients undergoing peritoneal dialysis (PD). In the current pilot study we explored the effects of dietary AGEs on the gut bacterial microbiota composition in similar patients. AGEs play an important role in the development and progression of cardiovascular (CVD) disease. Plasma concentrations of different bacterial products have been shown to predict the risk of incident major adverse CVD events independently of traditional CVD risk factors, and experimental animal models indicates a possible role AGEs might have on the gut microbiota population...
2017: PloS One
https://www.readbyqxmd.com/read/28930983/personalized-peptide-arrays-for-detection-of-hla-alloantibodies-in-organ-transplantation
#3
Pan Liu, Tomokazu Souma, Andrew Zu-Sern Wei, Xueying Xie, Xunrong Luo, Jing Jin
In organ transplantation, the function and longevity of the graft critically rely on the success of controlling immunological rejection reactivity against human leukocyte antigens (HLA). Histocompatibility guidelines are based on laboratory tests of anti-HLA immunity, which presents either as pre-existing or de novo generated HLA antibodies that constitute a major transplantation barrier. Current tests are built on a single-antigen beads (SAB) platform using a fixed set of ~100 preselected recombinant HLA antigens to probe transplant sera...
September 6, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28930852/does-body-shadow-improve-the-efficacy-of-virtual-reality-based-training-with-bts-nirvana-a-pilot-study
#4
Margherita Russo, Rosaria De Luca, Antonino Naro, Francesca Sciarrone, Bianca Aragona, Giuseppe Silvestri, Alfredo Manuli, Alessia Bramanti, Carmela Casella, Placido Bramanti, Rocco Salvatore Calabrò
BACKGROUND: Aim of the present study was to evaluate whether the presence of body shadows during virtual reality (VR) training with BTS NIRVANA (BTs-N) may lead to a better functional recovery. METHODS: We enrolled 20 poststroke rehabilitation inpatients, who underwent a neurocognitive-rehabilitative training consisting of 24 sessions (3 times a week for 8 weeks) of BTs-N. All the patients were randomized into 2 groups: semi-immersive virtual training with (S-IVTS group) or without (S-IVT group) body shadows...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28930794/clinical-and-confocal-microscopy-study-of-plasma-exeresis-for-nonsurgical-blepharoplasty-of-the-upper-eyelid-a-pilot-study
#5
Elena Rossi, Francesca Farnetani, Myrto Trakatelli, Silvana Ciardo, Giovanni Pellacani
BACKGROUND: Plasma exeresis is an evolving technique for nonsurgical treatment of several skin conditions. Reflectance confocal microscopy (RCM) is a noninvasive tool that allows the "in vivo" imaging of the skin. OBJECTIVE: To evaluate the clinical improvement and collagen remodeling of the upper eyelid dermatochalasis after plasma exeresis. METHODS: Ten patients were subjected to 3 interventions of plasma exeresis. Photographic and RCM images were acquired at T0 (baseline) and T1 (4-6 weeks after final plasma exeresis)...
September 19, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28930626/pilot-study-whole-body-manual-subcutaneous-adipose-tissue-sat-therapy-improved-pain-and-sat-structure-in-women-with-lipedema
#6
Karen L Herbst, Christopher Ussery, Alyna Eekema
Background Lipedema is a common painful subcutaneous adipose tissue (SAT) disorder in women affecting the limbs. SAT therapy is a manual therapy to improve soft tissue quality. Objective Determine if SAT therapy improves pain and structure of lipedema SAT. Design Single arm prospective pilot study. Setting Academic medical center. Patients Seven women, 46 ± 5 years, weight 90 ± 19 kg, with lipedema. Intervention Twelve 90-min SAT therapy sessions over 4 weeks. Outcomes Dual X-ray absorptiometry (DXA) scans, SAT ultrasound (Vevo 2100), leg volumetrics, skin caliper assessment, tissue exam, weight, resting metabolic rate, pain assessment, lower extremity functional scale (LEFS) and body shape questionnaire (BSQ) at baseline and end of study...
September 20, 2017: Hormone Molecular Biology and Clinical Investigation
https://www.readbyqxmd.com/read/28930297/estimated-radiation-exposure-of-german-commercial-airline-cabin-crew-in-the-years-1960-2003-modeled-using-dose-registry-data-for-2004-2015
#7
Daniel Wollschläger, Gaël Paul Hammer, Thomas Schafft, Steffen Dreger, Maria Blettner, Hajo Zeeb
Exposure to ionizing radiation of cosmic origin is an occupational risk factor in commercial aircrew. In a historic cohort of 26,774 German aircrew, radiation exposure was previously estimated only for cockpit crew using a job-exposure matrix (JEM). Here, a new method for retrospectively estimating cabin crew dose is developed. The German Federal Radiation Registry (SSR) documents individual monthly effective doses for all aircrew. SSR-provided doses on 12,941 aircrew from 2004 to 2015 were used to model cabin crew dose as a function of age, sex, job category, solar activity, and male pilots' dose; the mean annual effective dose was 2...
September 20, 2017: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/28930273/qigong-exercises-for-the-management-of-type-2-diabetes-mellitus
#8
REVIEW
Amy L Putiri, Jacqueline R Close, Harold Ryan Lilly, Nathalie Guillaume, Guan-Cheng Sun
Background: The purpose of this article is to clarify and define medical qigong and to identify an appropriate study design and methodology for a large-scale study looking at the effects of qigong in patients with type 2 diabetes mellitus (T2DM), specifically subject enrollment criteria, selection of the control group and study duration. Methods: A comprehensive literature review of English databases was used to locate articles from 1980-May 2017 involving qigong and T2DM. Control groups, subject criteria and the results of major diabetic markers were reviewed and compared within each study...
August 9, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28930248/the-effect-of-acupuncture-on-visual-function-in-patients-with-congenital-and-acquired-nystagmus
#9
Tilo Blechschmidt, Maike Krumsiek, Margarita G Todorova
Background: The aim of this study is to examine the short-term effect of visual function following acupuncture treatment in patients with congenital idiopathic nystagmus and acquired nystagmus (CIN and AN). Methods: An observational pilot study on six patients with confirmed diagnosis of nystagmus (three CIN and three AN patients (2♀, 4♂; mean age 42.67; SD ± 20.57 y)), was performed. Acupuncture treatment was done following a standardized protocol applying needle-acupuncture on the body and the ears. The treatment was scheduled with 10 sessions of 30 min duration over five weeks...
May 23, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28930237/qigong-exercise-may-reduce-serum-tnf-%C3%AE-levels-and-improve-sleep-in-people-with-parkinson-s-disease-a-pilot-study
#10
Sanghee Moon, Marshall Schmidt, Irina V Smirnova, Yvonne Colgrove, Wen Liu
Background: Inflammatory cytokine levels are often elevated in people with Parkinson's disease (PD). People with PD often experience sleep disturbances that significantly impact quality of life. Past studies suggest inflammatory cytokines may be associated with various symptoms of PD. Benefits of Qigong, a mind-body exercise, have been shown in different neurological conditions, but there is still a lack of clinical evidence in the PD population. Methods: Ten people with PD were recruited and randomly assigned into two groups receiving six weeks of Qigong (experimental group) or sham Qigong (control group) intervention...
April 23, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28930235/current-usage-of-traditional-chinese-medicine-for-breast-cancer-a-narrative-approach-to-the-experiences-of-women-with-breast-cancer-in-australia-a-pilot-study
#11
Dianna Porter, Suzanne Cochrane, Xiaoshu Zhu
Background: The use of Traditional Chinese Medicine (TCM) by breast cancer patients is growing. Few studies have examined the complexity of breast cancer survivors' attitudes, lived experiences, barriers, and perceptions in using TCM as part of their treatment journey. This article examines breast cancer survivors' experiences, perceptions of, and benefits (or not) in using TCM. Methods: Qualitative research, using semi-structured interviews, was the chosen methodology. Results: Participants used TCM as a form of self-help and as a complement, not an alternative, to standard care...
April 21, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28930234/nonspecific-feelings-expected-and-experienced-during-or-immediately-after-electroacupuncture-a-pilot-study-in-a-teaching-situation
#12
David F Mayor, Lara S McClure, J Helgi Clayton McClure
BACKGROUND: Some feelings elicited by acupuncture-type interventions are "nonspecific", interpretable as resulting from the placebo effect, our own self-healing capacities-or, indeed, the flow of qi. Expectation is thought to contribute to these nonspecific effects. Here we describe the use of two innovative 20-item questionnaires (EXPre20 and EXPost20) in a teaching situation. METHODS: Respondents were acupuncture students or practitioners on electroacupuncture (EA) training courses (N = 68)...
April 8, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28929925/content-analysis-of-a-participant-directed-intervention-to-optimize-activity-engagement-of-older-adult-cancer-survivors
#13
Kathleen Doyle Lyons, Robin Newman, Anna M Adachi-Mejia, Jessica Whipple, Mark T Hegel
Many older adult cancer survivors reduce their activity level during and after cancer treatment. Occupational therapy interventions need to flexibly address various obstacles to occupational engagement that survivors may face. The aim of this analysis was to describe the content of a participant-directed occupational therapy intervention for older adults with cancer. Content analysis was used to describe the treatment session data from the experimental arm of a pilot randomized controlled trial in terms of activities addressed, obstacles reported, and treatment strategies utilized...
September 1, 2017: OTJR: Occupation, Participation and Health
https://www.readbyqxmd.com/read/28929821/effects-of-a-translational-community-based-multimodal-exercise-program-on-quality-of-life-and-the-influence-of-start-delay-on-physical-function-and-quality-of-life-in-breast-cancer-survivors-a-pilot-study
#14
Michael Paul Foley, Scott Michael Hasson, Eydie Kendall
The purpose of this investigation was 2-fold: (1) to investigate the effects of a translational 12-week community-based multimodal exercise program on quality of life (QoL) in breast cancer survivors (BCS) and (2) to examine the influence of a start delay on physical function and QoL in BCS. Fifty-two female BCS completed a 12-week program consisting of 90-minute supervised exercise sessions at a frequency of 2 supervised sessions per week. Exercise sessions consisted of three 30-minute components: (1) aerobic conditioning, (2) resistance exercise training, and (3) balance and flexibility training...
September 1, 2017: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/28929560/minocycline-and-matrix-metalloproteinase-inhibition-in-acute-intracerebral-hemorrhage-a-pilot-study
#15
J J Chang, M Kim-Tenser, B A Emanuel, G M Jones, K Chapple, A Alikhani, N Sanossian, W J Mack, G Tsivgoulis, A V Alexandrov, T Pourmotabbed
BACKGROUND AND PURPOSE: Intracerebral hemorrhage (ICH) is a devastating cerebrovascular disorder with high morbidity and mortality. Minocycline is a matrix metalloproteinase-9 (MMP-9) inhibitor that may attenuate secondary mechanisms of injury in ICH. The feasibility and safety of minocycline in ICH patients were evaluated in a pilot, double-blinded, placebo-controlled randomized clinical trial. METHODS: Patients with acute onset (<12 h from symptom onset) ICH and small initial hematoma volume (<30 ml) were randomized to high-dose (10 mg/kg) intravenous minocycline or placebo...
September 20, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28929392/preventing-early-bouncebacks-to-the-neurointensive-care-unit-a-retrospective-analysis-and-quality-improvement-pilot
#16
David G Coughlin, Monisha A Kumar, Neha N Patel, Rebecca L Hoffman, Scott E Kasner
BACKGROUND: Early unplanned readmissions of "bouncebacks" to intensive care units are a healthcare quality metric and result in higher mortality and greater cost. Few studies have examined bouncebacks to the neurointensive care unit (neuro-ICU), and we sought to design and implement a quality improvement pilot to reduce that rate. METHODS: First, we performed a retrospective chart review of 504 transfers to identify potential bounceback risk factors. Risk factors were assessed on the day of transfer by the transferring physician identifying patients as "high risk" or "low risk" for bounceback...
September 19, 2017: Neurocritical Care
https://www.readbyqxmd.com/read/28929327/possible-long-term-efficacy-of-sitagliptin-a-dipeptidyl-peptidase-4-inhibitor-for-slowly-progressive-type-1-diabetes-spiddm-in-the-stage-of-non-insulin-dependency-an-open-label-randomized-controlled-pilot-trial-span-s
#17
Takuya Awata, Akira Shimada, Taro Maruyama, Yoichi Oikawa, Nobuyuki Yasukawa, Susumu Kurihara, Yumi Miyashita, Masako Hatano, Yuichi Ikegami, Masafumi Matsuda, Masataka Niwa, Youichiro Kazama, Shoichiro Tanaka, Tetsuro Kobayashi
INTRODUCTION: We tested the hypothesis that dipeptidyl peptidase-4 (DPP-4) inhibitors are effective in preserving the β-cell function for long-term periods in patients with slowly progressive type 1 diabetes (SPIDDM) or latent autoimmune diabetes in adults (LADA). METHODS: In the present open-label, randomized, controlled trial, 14 non-insulin-requiring diabetic patients with glutamic acid decarboxylase autoantibodies (GADAb) were randomly assigned to receive either sitagliptin (S group) or pioglitazone (P group)...
September 19, 2017: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/28929253/positive-rheotaxis-extended-drop-a-one-step-procedure-to-select-and-recover-sperm-with-mature-chromatin-for-intracytoplasmic-sperm-injection
#18
Hamilton De Martin, Marcello S Cocuzza, Bruno C Tiseo, Guilherme J A Wood, Eduardo P Miranda, Pedro A A Monteleone, José Maria Soares, Paulo C Serafini, Miguel Srougi, Edmund C Baracat
PURPOSE: The purpose of this study was to develop a novel one-step ICSI approach to select sperm with better chromatin maturity than the conventional method. METHODS: This was a pilot diagnostic study, which prospectively recruited men during a 6-month period in a University-affiliated infertility centre. Forty consecutive semen samples were provided for analysis. The positive rheotaxis extended drop (PRED) was set up creating a pressure and viscosity gradient. Each semen sample was divided into four aliquots: one aliquot for density gradient centrifugation (DGC), two aliquots for PRED (fresh semen (PRED-FS) and processed semen (PRED-DGC)), and one aliquot as the control (FS)...
September 19, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28929209/upper-urinary-tract-effects-after-irreversible-electroporation-ire-of-human-localised-renal-cell-carcinoma-rcc-in-the-irene-pilot-phase-2a-ablate-and-resect-study
#19
J J Wendler, M Pech, J Köllermann, B Friebe, S Siedentopf, S Blaschke, D Schindele, M Porsch, D Baumunk, J Jürgens, F Fischbach, J Ricke, M Schostak, M Böhm, U B Liehr
PURPOSE: Irreversible electroporation (IRE) is a new potential ablation modality for small renal masses. Animal experiments have shown preservation of the urine-collecting system (UCS). The purpose of this clinical study was to perform the first evaluation and comparison of IRE's effects on the renal UCS by using urinary cytology, magnetic-resonance imaging, and resection histology in men after IRE of pT1a renal-cell carcinoma (RCC). METHODS: Seven patients with biopsy-proven RCC pT1a cN0cM0 underwent IRE in a phase 2a pilot ablate-and-resect study (IRENE trial)...
September 19, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28928973/prospective-replication-study-implicates-the-catechol-o-methyltransferase-val-158-met-polymorphism-as-a-biomarker-for-the-response-to-morphine-in-patients-with-cancer
#20
Hiromichi Matsuoka, Chihiro Makimura, Atsuko Koyama, Yoshihiko Fujita, Junji Tsurutani, Kiyohiro Sakai, Ryo Sakamoto, Kazuto Nishio, Kazuhiko Nakagawa
Genetic differences in humans cause clinical difficulties in opioid treatment. Previous studies indicate that a single nucleotide polymorphism in the catechol-O-methyltransferase (COMT) gene (rs4680; p.Val(158)Met) may present as a predictive biomarker for the response to morphine treatment. In our previous pilot exploratory study, patients with a G/G genotype were demonstrated to require a higher dose of morphine, compared with patients with A/A and A/G genotypes. In the present study, the aim was to replicate the findings in an independent cohort of opioid-treatment-naïve patients exhibiting various types of cancer...
October 2017: Biomedical Reports
keyword
keyword
37172
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"