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https://www.readbyqxmd.com/read/28806842/clowns-in-paediatric-surgery-less-anxiety-and-more-oxytocin-a-pilot-study
#1
Tabea Scheel, Dorothea Hoeppner, Anne Grotevendt, Winfried Barthlen
Background Hospital stays and medical interventions are accompanied by worries and anxiety in children and parents. Recent studies show that hospital clowns may reduce anxiety and enhance well-being. However, so far studies are based solely on subjective measures and clowns are usually not integrated in medical routine. With this pilot study, we aim to provide both psychological and physiological evidence of positive effects of clowns' interventions in hospitalized children. Patients/Method In a consecutive randomized intervention-control group design with 31 children aged 4 to 13 years, 17 patients were accompanied by a clown prior to surgery or during ward round (intervention group) and 14 were not (control group)...
August 14, 2017: Klinische Pädiatrie
https://www.readbyqxmd.com/read/28806612/pilots-using-selective-serotonin-reuptake-inhibitors-compared-to-other-fatally-injured-pilots
#2
Paul Rogers, Christy Hileman, Guillermo Salazar, Kacey Cliburn, Lawrence Paskoff, William Hathaway, Kevin Gildea, Victor Hugo Tejera Villalaz
Selective Serotonin Reuptake Inhibitors (SSRI) were a disqualifying medication for U.S. civil pilots before April 5, 2010. After this date, a Federal Aviation Administration policy was created that allowed airmen, on select SSRIs, a pathway to hold a valid medical certificate. The purpose of this study was to provide a detailed look at SSRIs in the U.S. pilot population since the inception of this new policy. We examined the toxicology results from fatally injured airmen in addition to outcomes concerning pilots who are participating in the program...
August 11, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28806554/metal-bioaccumulation-and-biomarkers-of-effects-in-caged-mussels-exposed-in-the-athabasca-oil-sands-area
#3
M Pilote, C André, P Turcotte, F Gagné, C Gagnon
The Athabasca oil sands deposit is the world's largest known reservoir of crude bitumen and the third-largest proven crude oil reserve. Mining activity is known to release contaminants, including metals, and to potentially impact the aquatic environment. The purpose of this study was to determine the impacts of oil sands mining on water quality and metal bioaccumulation in mussels from the Fort McMurray area in northern Alberta, Canada. The study presents two consecutive years of contrasting mussel exposure conditions (low and high flows)...
August 11, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28806341/impact-of-cochlear-implantation-on-cognitive-functions-of-older-adults-pilot-test-results
#4
Dona M P Jayakody, Peter L Friedland, Esmeralda Nel, Ralph N Martins, Marcus D Atlas, Hamid R Sohrabi
BACKGROUND: A significant relationship between hearing loss and cognitive impairment has been previously reported. Overall, improvement in speech perception in quiet and quality of life has been observed after cochlear implantation. However, the impact of hearing loss treatment using cochlear implantation on cognitive functions is yet to be fully elucidated. OBJECTIVE: To investigate the impact of cochlear implantation on cognitive and psychological functions of older adults...
September 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28806335/a-smartphone-application-for-customized-frequency-table-selection-in-cochlear-implants
#5
Daniel Jethanamest, Mahan Azadpour, Annette M Zeman, Elad Sagi, Mario A Svirsky
HYPOTHESIS: A novel smartphone-based software application can facilitate self-selection of frequency allocation tables (FAT) in postlingually deaf cochlear implant (CI) users. BACKGROUND: CIs use FATs to represent the tonotopic organization of a normal cochlea. Current CI fitting methods typically use a standard FAT for all patients regardless of individual differences in cochlear size and electrode location. In postlingually deaf patients, different amounts of mismatch can result between the frequency-place function they experienced when they had normal hearing and the frequency-place function that results from the standard FAT...
September 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28806285/peritoneal-cavity-lavage-reduces-the-presence-of-mitochondrial-damage-associated-molecular-patterns-in-open-abdomen-patients
#6
Patricia Angellice Martinez-Quinones, Cameron Grant McCarthy, Caleb J Mentzer, Camilla Ferreira Wenceslau, Steven Barry Holsten, R Clinton Webb, Keith O'Malley
BACKGROUND: Mitochondrial damage-associated molecular patterns (mtDAMPs), such as mitochondrial DNA and N-formylated peptides, are endogenous molecules released from tissue after traumatic injury. mtDAMPs are potent activators of the innate immune system. They have similarities with bacteria, which allow mtDAMPs to interact with the same pattern recognition receptors and mediate the development of Systemic Inflammatory Response Syndrome (SIRS). Current recommendations for management of an open abdomen include returning to the operating room every 48 hours for peritoneal cavity lavage until definitive procedure...
August 12, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28806283/expanding-the-scope-of-quality-measurement-in-surgery-to-include-non-operative-care-results-from-the-acs-nsqip-emergency-general-surgery-pilot
#7
Michael W Wandling, Clifford Y Ko, Paul E Bankey, Chris Cribari, H Gill Cryer, Jose J Diaz, Therese M Duane, S Morad Hameed, Matthew M Hutter, Michael H Metzler, Justin L Regner, Patrick M Reilly, H David Reines, Jason L Sperry, Kristan L Staudenmayer, Garth H Utter, Marie L Crandall, Karl Y Bilimoria, Avery B Nathens
BACKGROUND: Patients managed non-operatively have been excluded from risk-adjusted benchmarking programs, including the American College of Surgeons (ACS) National Surgical Quality Improvement Program (NSQIP). Consequently, optimal performance evaluation is not possible for specialties like emergency general surgery (EGS) where non-operative management is common. We developed a multi-institutional EGS clinical data registry within ACS NSQIP that includes patients managed non-operatively to evaluate variability in non-operative care across hospitals and identify gaps in performance assessment that occur when only operative cases are considered...
August 12, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28806277/nursing-faculty-attitudes-and-practices-related-to-online-teaching
#8
Lisa Broussard, Kathleen Wilson
Online education as a teaching methodology is relatively new in higher education in comparison to traditional face-to-face instruction. There is often concern that the quality of online classes is inferior and that academic rigor is compromised when faculty are not engaged with students in a classroom. The purpose of this pilot study was to assess nursing faculty attitudes and practices regarding online teaching. Findings indicated that overall, faculty feel that achievement of student learning outcomes in online and hybrid settings is comparable to face-to-face and report excitement with most aspects of teaching online...
August 10, 2017: Nursing Education Perspectives
https://www.readbyqxmd.com/read/28806206/chronic-pain-and-associated-factors-in-india-and-nepal-a-pilot-study-of-the-vanderbilt-global-pain-survey
#9
Jenna L Walters, Kelly Baxter, Hannah Chapman, Tracy Jackson, Adinarayanan Sethuramachandran, Marcus Couldridge, Hem Raj Joshi, Pankaj Kundra, Xulei Liu, Divya Nair, Bonnie Sullivan, Matthew S Shotwell, Ryan J Jense, Nicholas J Kassebaum, K A Kelly McQueen
BACKGROUND: Evaluation and treatment of chronic pain worldwide are limited by the lack of standardized assessment tools incorporating consistent definitions of pain chronicity and specific queries of known social and psychological risk factors for chronic pain. The Vanderbilt Global Pain Survey (VGPS) was developed as a tool to address these concerns, specifically in the low- and middle-income countries where global burden is highest. METHODS: The VGPS was developed using standardized and cross-culturally validated metrics, including the Brief Pain Inventory and World Health Organization Disability Assessment Scale, as well as the Pain Catastrophizing Scale, the Fibromyalgia Survey Questionnaire along with queries about pain attitudes to assess the prevalence of chronic pain and disability along with its psychosocial and emotional associations...
August 10, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28806128/exploring-the-motivations-for-body-piercing-a-pilot-study
#10
Andrew Crowther, Rachel Kornhaber, Fredrik Velander, Sally Drummond, Michelle Cleary
No abstract text is available yet for this article.
August 2017: Issues in Mental Health Nursing
https://www.readbyqxmd.com/read/28806079/pilot-in-vivo-structure-activity-relationship-of-dihydromethys-ticin-in-blocking-4-methylnitrosamino-1-3-pyridyl-1-butanone-induced-o6-methylguanine-and-lung-tumor-in-a-j-mice
#11
Manohar Puppala, Sreekanth C Narayanapillai, Pablo Leitzman, Haifeng Sun, Pramod Upadhyaya, M Gerard O'Sullivan, Stephen S Hecht, Chengguo Xing
(+)-Dihydromethysticin was recently identified as a promising lung cancer chemopreventive agent while (+)-dihydrokavain was completely ineffective. A pilot in vivo structure-activity relationship (SAR) was explored, evaluating the efficacy of its analogs in blocking 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced short-term O6-methylguanine and long-term adenoma formation in the lung tissues in A/J mice. Both results revealed cohesive SARs, demonstrating that the methylenedioxy functional group in DHM is essential while the lactone functional group tolerates modifications...
August 14, 2017: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28805606/detection-of-sea-type-%C3%AE-thalassemia-in-embryo-biopsies-by-digital-pcr
#12
Ta-Hsien Lee, Ya-Chiung Hsu, Chia Lin Chang
OBJECTIVE: Accurate and efficient pre-implantation genetic diagnosis (PGD) based on the analysis of single or oligo-cells is needed for timely identification of embryos that are affected by deleterious genetic traits in in vitro fertilization (IVF) clinics. Polymerase chain reaction (PCR) is the backbone of modern genetic diagnoses, and a spectrum of PCR-based techniques have been used to detect various thalassemia mutations in prenatal diagnosis (PND) and PGD. Among thalassemias, SEA-type α-thalassemia is the most common variety found in Asia, and can lead to Bart's hydrops fetalis and serious maternal complications...
August 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28805422/stakeholder-perspectives-on-a-toolkit-to-enhance-caregiver-participation-in-community-based-child-mental-health-services
#13
Rachel Haine-Schlagel, Molly Mechammil, Lauren Brookman-Frazee
Client engagement in services is a critical element of effective community-based child and family mental health service delivery. Caregiver engagement is particularly important, as caregivers often serve as gatekeepers to child mental health care and typically must consent for services, facilitate service attendance, and are often the target of intervention themselves. Unfortunately, caregiver engagement has been identified as a significant challenge in community-based child mental health services. To address this gap, the Parent And Caregiver Active Participation Toolkit (PACT), which includes therapist training and participation tools for caregivers and therapists, was developed...
August 2017: Psychological Services
https://www.readbyqxmd.com/read/28805414/a-culturally-adapted-family-intervention-for-rural-pacific-island-veterans-with-ptsd
#14
Julia M Whealin, Athena C Yoneda, Dawna Nelson, Todd S Hilmes, Michelle M Kawasaki, Oscar H Yan
The Veterans Affairs mission to provide equitable, accessible, and patient-centered care necessitates that culturally appropriate interventions are available when cultural differences may jeopardize engagement in care. However, within the VA, wounded warriors residing in rural areas in the Pacific Islands have been offered interventions that were developed and tested using largely urban mainland populations. The objectives of this article were to (a) document the cultural adaptation of a cognitive-behavioral clinical intervention for use by rural Pacific Island veterans, and (b) report feasibility data for the intervention...
August 2017: Psychological Services
https://www.readbyqxmd.com/read/28805239/a-comparison-of-gastric-emptying-of-soluble-solid-meals-and-clear-fluids-matched-for-volume-and-energy-content-a-pilot-crossover-study
#15
T Okabe, H Terashima, A Sakamoto
We previously demonstrated that the gastric emptying time of different liquids with the same volume mainly depended on their energy content, regardless of differences in composition. In this crossover study, we investigated whether the same applies when soluble solid foods are ingested with water. Ten healthy volunteers ingested one of five test diets consisting of two test meals (Calorie Mate(®) 100 and 200 kcal) and three test solutions (water and glucose solutions of 100 and 200 kcal), each given in a volume of 400 ml, and then underwent ultrasonography to measure the gastric antral cross-sectional area every 10 min for 120 min...
August 14, 2017: Anaesthesia
https://www.readbyqxmd.com/read/28804505/an-etiologic-prediction-model-incorporating-biomarkers-to-predict-the-bladder-cancer-risk-associated-with-occupational-exposure-to-aromatic-amines-a-pilot-study
#16
Giuseppe Mastrangelo, Angela Carta, Cecilia Arici, Sofia Pavanello, Stefano Porru
BACKGROUND: No etiological prediction model incorporating biomarkers is available to predict bladder cancer risk associated with occupational exposure to aromatic amines. METHODS: Cases were 199 bladder cancer patients. Clinical, laboratory and genetic data were predictors in logistic regression models (full and short) in which the dependent variable was 1 for 15 patients with aromatic amines related bladder cancer and 0 otherwise. The receiver operating characteristics approach was adopted; the area under the curve was used to evaluate discriminatory ability of models...
2017: Journal of Occupational Medicine and Toxicology
https://www.readbyqxmd.com/read/28803820/titration-a-randomized-study-to-assess-2-treatment-algorithms-with-new-insulin-glargine-300-units-ml
#17
Jean-François Yale, Lori Berard, Mélanie Groleau, Pasha Javadi, John Stewart, Stewart B Harris
OBJECTIVE: It was uncertain whether an algorithm that involves increasing insulin dosages by 1 unit/day may cause more hypoglycemia with the longer-acting insulin glargine 300 units/mL (GLA-300). The objective of this study was to compare safety and efficacy of 2 titration algorithms, INSIGHT and EDITION, for GLA-300 in people with uncontrolled type 2 diabetes mellitus, mainly in a primary care setting. METHODS: This was a 12-week, open-label, randomized, multicentre pilot study...
August 10, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28803769/urine-biomarkers-of-tubular-renal-cell-damage-for-the-prediction-of-acute-kidney-injury-after-cardiac-surgery-a-pilot-study
#18
Tanja Mayer, Daniel Bolliger, Markus Scholz, Oliver Reuthebuch, Michael Gregor, Patrick Meier, Martin Grapow, Manfred D Seeberger, Jens Fassl
OBJECTIVE: To evaluate the perioperative course of urine levels of the renal damage biomarkers tissue inhibitor of metalloproteinase 2 (TIMP-2) and insulin-like growth factor-binding protein 7 (IGFBP7) and to evaluate the predictive value of elevated TIMP-2 × IGFBP7 concentrations to predict acute kidney injury (AKI) early after cardiac on-pump surgery. DESIGN: Prospective, observational cohort study. SETTING: University hospital. PARTICIPANTS: The study comprised 110 consecutive patients undergoing elective cardiac surgery with cardiopulmonary bypass (CPB) between January and March 2014...
April 16, 2017: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/28803744/novel-1l-polyethylene-glycol-based-bowel-preparation-ner1006-for-overall-and-right-sided-colon-cleansing-a-randomized-controlled-phase-3-trial-versus-trisulfate
#19
Michael P DeMicco, Lucy B Clayton, Jeff Pilot, Michael S Epstein
BACKGROUND AND AIMS: NER1006 is the first 32 fluid ounce (1L) polyethylene glycol-based bowel preparation. This randomized, multicenter, colonoscopist/central reader-blinded Phase 3 non-inferiority trial assessed the efficacy, safety, and tolerability of NER1006 versus trisulfate for bowel cleansing. METHODS: Patients undergoing colonoscopy were randomized (1:1) to receive NER1006 or trisulfate, using evening/morning split-dosing administration. Blinded central readers used the validated Harefield Cleansing Scale (HCS) to evaluate 2 alternative primary endpoints: overall bowel cleansing success and high-quality cleansing of the ascending colon/cecum...
August 10, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28803598/adapting-the-standardised-computer-and-interview-based-24-h-dietary-recall-method-globodiet-for-dietary-monitoring-in-latin-america
#20
Silvia Bel-Serrat, Viktoria Knaze, Genevieve Nicolas, Dirce M Marchioni, Josiane Steluti, Aline Mendes, Sandra P Crispim, Regina M Fisberg, Rosangela A Pereira, Marina C Araujo, Rosely Sichieri, Edna M Yokoo, Tania Sánchez-Pimienta, Tania C Aburto, Lilia S Pedraza, Nadia Slimani
OBJECTIVE: The present study describes the procedure and approaches needed to adapt and harmonise the GloboDiet methodology, a computer- and interview-based 24 h dietary recall, for use in two Latin American pilot countries, Brazil and Mexico. DESIGN: About seventy common and country-specific databases on foods, recipes, dietary supplements, quantification methods and coefficients were customised and translated following standardised guidelines, starting from existing Spanish and Portuguese versions...
August 14, 2017: Public Health Nutrition
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