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https://www.readbyqxmd.com/read/28922903/banking-on-living-kidney-donors-a-new-way-to-facilitate-donation-without-compromising-on-ethical-values
#1
Dominique E Martin, Gabriel M Danovitch
Public surveys conducted in many countries report widespread willingness of individuals to donate a kidney while alive to a family member or close friend, yet thousands suffer and many die each year while waiting for a kidney transplant. Advocates of financial incentive programs or "regulated markets" in kidneys present the problem of the kidney shortage as one of insufficient public motivation to donate, arguing that incentives will increase the number of donors. Others believe the solutions lie-at least in part-in facilitating so-called "altruistic donation;" harnessing the willingness of relatives and friends to donate by addressing the many barriers which serve as disincentives to living donation...
October 1, 2017: Journal of Medicine and Philosophy
https://www.readbyqxmd.com/read/28922654/student-s-perception-about-innovative-teaching-learning-practices-in-forensic-medicine
#2
Sanjay Gupta, Utsav N Parekh, Jaishree D Ganjiwale
BACKGROUND: Since decades, Forensic Medicine is mainly taught by didactic methods but in last couple of years some other teachinglearning and assessment methods are also introduced at some places which also lacks uniformity. Feedback from learners is most fundamental aspect to assess effectiveness of applied methods, but is not implemented in practice at most medical schools in India. Unfortunately, medical students are deprived of this practical empowerment and thus may not be efficient enough to contribute potentially to the justice system during their professional life...
September 11, 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/28922652/a-pilot-study-of-loss-aversion-for-drug-and-non-drug-commodities-in-cocaine-users
#3
Justin C Strickland, Joshua S Beckmann, Craig R Rush, William W Stoops
BACKGROUND: Numerous studies in behavioral economics have demonstrated that individuals are more sensitive to the prospect of a loss than a gain (i.e., loss aversion). Although loss aversion has been well described in "healthy" populations, little research exists in individuals with substance use disorders. This gap is notable considering the prominent role that choice and decision-making play in drug use. The purpose of this pilot study was to evaluate loss aversion in active cocaine users...
September 12, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28922438/endocan-serum-levels-in-patients-with-non-alcoholic-fatty-liver-disease-with-or-without-type-2-diabetes-mellitus-a-pilot-study
#4
Marcello Dallio, Mario Masarone, Giuseppe Gerardo Caprio, Rosa Di Sarno, Concetta Tuccillo, Ferdinando Carlo Sasso, Marcello Persico, Carmela Loguercio, Alessandro Federico
BACKGROUND AND AIMS: Non-alcoholic fatty liver disease (NAFLD) is emerging as an independent cardiovascular risk factor. Recently, Endocan has been studied as an early marker of endothelial dysfunction. Our aim was to evaluate Endocan serum levels in patients with NAFLD with or without type 2 diabetes mellitus. METHOD: We enrolled 56 patients: 19 with NAFLD and 37 with type 2 diabetes mellitus with or without NAFLD, and compared them to 25 healthy controls. Endocan serum level was measured by using the ELISA EndoMark assay...
September 2017: Journal of Gastrointestinal and Liver Diseases: JGLD
https://www.readbyqxmd.com/read/28922309/quantifying-the-physiological-stress-response-to-simulated-maritime-pilotage-tasks-the-influence-of-task-complexity-and-pilot-experience
#5
Luana C Main, Alexander Wolkow, Timothy P Chambers
OBJECTIVE: The aim of this study was to quantify the stress associated with performing maritime pilotage tasks in a high-fidelity simulator. METHODS: Eight trainee and 13 maritime pilots completed two simulated pilotage tasks of varying complexity. Salivary cortisol samples were collected pre- and post-simulation for both trials. Heart rate was measured continuously throughout the study. RESULTS: Significant changes in salivary cortisol (P = 0...
September 15, 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28922279/translation-cross-cultural-adaptation-and-validation-of-the-farsi-version-of-nih-task-force-s-recommended-multidimensional-minimal-dataset-for-research-on-chronic-low-back-pain
#6
Pardis Noormohammadpour, Bahareh Tavana, Mohammad Ali Mansournia, Mehdi Zeinalizadeh, Babak Mirzashahi, Mohsen Rostami, Ramin Kordi
STUDY DESIGN: Translation and cultural adaptation of the National Institutes of Health (NIH) Task Force's minimal dataset. OBJECTIVE: The purpose of this study was to evaluate validity and reliability of the Farsi version of NIH Task Force's recommended multidimensional minimal dataset for research on chronic low back pain (CLBP). SUMMARY OF BACKGROUND DATA: Considering the high cost of CLBP and its increasing prevalence, NIH Pain Consortium developed research standards (including recommendations for definitions, a minimum dataset, and outcomes' report) for studies regarding CLBP...
September 15, 2017: Spine
https://www.readbyqxmd.com/read/28922268/early-exercise-in-critically-ill-youth-and-children-a-preliminary-evaluation-the-weecycle-pilot-trial
#7
Karen Choong, Saif Awladthani, Adeeb Khawaji, Heather Clark, Asm Borhan, Ji Cheng, Sam Laskey, Charmaine Neu, Aimee Sarti, Lehana Thabane, Brian W Timmons, Katina Zheng, Samah Al-Harbi
OBJECTIVES: To determine the feasibility of conducting a full trial evaluating the efficacy of early mobilization using in-bed cycling as an adjunct to physiotherapy, on functional outcomes in critically ill children. DESIGN: Single center, pilot, randomized controlled trial. SETTING: Twelve-bed tertiary care, medical-surgical PICU at McMaster Children's Hospital, Hamilton, ON, Canada. PATIENTS: Children 3-17 years old who were limited to bed-rest with an expected PICU stay of at least 48 hours...
September 15, 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28922238/primary-central-nervous-system-lymphoma-time-for-diagnostic-biomarkers-and-biotherapies
#8
Louis Royer-Perron, Khê Hoang-Xuan, Agusti Alentorn
PURPOSE OF REVIEW: Primary central nervous system lymphoma (PCNSL) is a rare cancer with a somber prognosis in older patients, which it affects predominantly. Only in recent years have molecular alterations characterizing PCNSL been thoroughly described. This opens possibilities for the use of targeted therapies. Developments in imaging and biomarkers have also great potential to help clinicians faced with diagnostic and prognostic uncertainties. RECENT FINDINGS: Several biomarkers for PCNSL, such as different microRNAs, which could be tested in cerebrospinal fluid and vitreous fluid, and IL-10, which has been shown to have excellent sensitivity and specificity in the cerebrospinal fluid, have emerged in the last years...
September 15, 2017: Current Opinion in Neurology
https://www.readbyqxmd.com/read/28922226/effect-of-high-inspiratory-oxygen-fraction-on-endothelial-function-in-healthy-volunteers-a-randomized-controlled-crossover-pilot-study
#9
Mikkel Hjordt Holm Larsen, Sarah Ekeloef, Dunja Kokotovic, Anne-Marie Schou-Pedersen, Jens Lykkesfeldt, Ismail Gögenür
It has been suggested that high inspiratory oxygen concentrations during anesthesia may be associated with higher postoperative mortality due to endothelial dysfunction. A randomized controlled crossover study was conducted with 25 healthy male volunteers. They inhaled an oxygen concentration of 30% and 80%. The endothelial function was assessed using noninvasive digital pulse amplitude tonometry (EndoPAT) supported by endothelial biomarkers. The difference in endothelial function between the 2 treatments was 0...
September 14, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28922185/a-pilot-study-to-precisely-quantify-forces-applied-by-sonographers-while-scanning-a-step-toward-reducing-ergonomic-injury
#10
Manish Dhyani, Shawn C Roll, Matthew W Gilbertson, Melanie Orlowski, Arash Anvari, Qian Li, Brian Anthony, Anthony E Samir
BACKGROUND: There is a significantly high rate of work-related musculsokeletal injuries in sonography professionals. To date, assessment of risk factors for work- related injuries in sonographers has been based primarily on surveys, subjective reports, and observational methods. There is a need to develop quantitative techniques to better understand risk factors and develop preventive interventions. OBJECTIVE: We pilot tested a high-resolution force-measuring probe capable of precisely measuring forces applied through the transducer by sonographers and used this novel direct measurement technique to evaluate forces during abdominal imaging...
September 14, 2017: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://www.readbyqxmd.com/read/28922065/a-study-examining-the-effect-of-a-short-bout-of-postprandial-walking-on-the-glycemic-effect-of-a-meal-type-1-diabetes
#11
Samantha L Hinojosa, Cynthia J Heiss
OBJECTIVE: The purpose of this pilot study was to determine whether 15 minutes of postprandial walking has an effect on the glycemic response to a breakfast beverage in individuals with type 1 diabetes (T1DM). METHODS: Seven participants, aged 22.3 ± 4.3 years, with T1DM using intensive insulin therapy completed 2 days of data collection. On day 1, participants measured baseline fasting blood glucose (BG) with a glucometer, consumed an 8-ounce Boost® beverage (41 grams carbohydrate), administered a bolus of insulin according to the carbohydrate load and fasting BG, and sat quietly, repeating BG measurements 15, 30, 60, 90, and 120 minutes after consumption...
September 18, 2017: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/28922051/effect-of-hospital-simulation-tutorials-on-nursing-and-pharmacy-student-perception-of-interprofessional-collaboration-findings-from-a-pilot-study
#12
Paulina Stehlik, Astrid Frotjold, Carl R Schneider
Interprofessional learning (IPL) during formal training enables interprofessional collaboration (IPC) in the workforce; however, on-campus IPL opportunities are seldom incorporated into curricula. We describe the development and implementation of two hospital simulation tutorials between nursing and pharmacy students. Students were required to provide "usual care" to a simulated patient at admission and discharge. A pre-post survey design was used to evaluate changes in Interdisciplinary Education Perception Scale (IEPS) score and student perceived educational value of the tutorials...
September 18, 2017: Journal of Interprofessional Care
https://www.readbyqxmd.com/read/28921826/growing-evidence-of-the-beneficial-effects-of-a-marine-protein-based-dietary-supplement-for-treating-hair-loss
#13
REVIEW
Carl S Hornfeldt
BACKGROUND: Hair loss is a common condition among women with a range of causes including nutritional deficiencies. AIMS: To review the clinical data supporting the use of an oral marine supplement designed to promote hair growth. PATIENTS/METHODS: Adult women with temporary thinning hair. Following an initial pilot study, five randomized, double-blind studies assessed the effectiveness of the oral marine supplement for promoting hair growth...
September 16, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28921814/nabilone-pharmacotherapy-for-cannabis-dependence-a-randomized-controlled-pilot-study
#14
Kevin P Hill, Matthew D Palastro, Staci A Gruber, Garrett M Fitzmaurice, Shelly F Greenfield, Scott E Lukas, Roger D Weiss
BACKGROUND AND OBJECTIVES: We assessed the safety, tolerability, and preliminary efficacy of nabilone, a cannabinoid agonist, to treat cannabis dependence. METHODS: Eighteen adults with DSM-IV cannabis dependence were randomized to receive either 2 mg/day of nabilone (n = 10) or placebo (n = 8) for 10 weeks in addition to medication management. Twelve participants, six in each group, completed treatment. The safety and tolerability of nabilone was assessed at each visit...
September 18, 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28921781/valganciclovir-vgcv-followed-by-cytomegalovirus-cmv-hyperimmune-globulin-compared-to-vgcv-for-200-days-in-abdominal-organ-transplant-recipients-at-high-risk-for-cmv-infection-a-prospective-randomized-pilot-study
#15
James N Fleming, David J Taber, Nicole A Weimert, Satish Nadig, John W McGillicuddy, Charles F Bratton, Prabhakar K Baliga, Kenneth D Chavin
BACKGROUND: With the advent of effective antivirals against cytomegalovirus (CMV), use of CMV hyperimmune globulin has decreased. Although antiviral prophylaxis in patients at high risk for CMV is effective, many patients still have late infection, never developing antibodies sufficient to achieve immunity. Utilizing a combination of antiviral and CMV immunoglobulin G may allow patients to achieve immunity and decrease late CMV infections. METHODS: This was a prospective randomized, open-label, pilot study comparing valganciclovir (VGCV) prophylaxis for 200 days vs VGCV for 100 days followed by CMV HIG in abdominal transplant recipients at high risk for CMV...
September 16, 2017: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://www.readbyqxmd.com/read/28921780/factors-associated-with-attrition-in-substance-using-patients-enrolled-in-an-intensive-outpatient-program
#16
James Mckowen, Nicholas Carrellas, Courtney Zulauf, Emin Nalan Ward, Ronna Fried, Timothy Wilens
BACKGROUND AND OBJECTIVES: Data suggest individuals with substance use disorders (SUD) have high rates of attrition from treatment and exhibit impairments on measures of executive functioning (EF). The primary aim of this pilot study was to investigate if EF is associated with attrition from a 1 month intensive outpatient program (IOP) for SUD, and examine the feasibility of implementing the project. METHODS: Baseline neurocognitive functioning was assessed by the Cambridge Neuropsychological Test Automated Battery (CANTAB) and the self-reported Behavior Rating Inventory of Executive Functioning (BRIEF-A) questionnaire...
September 18, 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28921556/dating-and-sexual-violence-research-in-the-schools-balancing-protection-of-confidentiality-with-supporting-the-welfare-of-survivors
#17
Jill D Sharkey, Lauren A Reed, Erika D Felix
Rigorous research and program evaluation are needed to understand the experience of dating and sexual violence among youth and the impact of prevention and intervention efforts. Our dilemma in doing this work occurred when youth disclosed dating and sexual violence on a research survey. What responsibility do researchers have to protect survivors' confidentiality as a research participant versus taking steps to ensure the student has the opportunity to access help? In our evaluation of a pilot dating violence prevention program, our protocols employed widely used procedures for providing resources to participants upon their completion of the survey and de-identifying survey data...
September 18, 2017: American Journal of Community Psychology
https://www.readbyqxmd.com/read/28921391/effects-of-web-based-interventions-on-cancer-patients-symptoms-review-of-randomized-trials
#18
REVIEW
N Fridriksdottir, S Gunnarsdottir, S Zoëga, B Ingadottir, E J G Hafsteinsdottir
PURPOSE: Symptom management is of high priority in cancer care. Information and communication technology allows interventions to be provided through the internet to enhance the delivery of care. This study aimed to review the effects of web-based interventions on cancer patients' symptoms. METHODS: MEDLINE, PSychINFO, PubMed, CINAHL, and Cochrane databases were systematically searched. Included were randomized controlled trials (RCTs), pilot RCTs, or quasi-experimental (QE) studies focusing on web-based interventions in adult cancer patients with at least one outcome primary or secondary, in terms of symptoms, treatment side effects, or distress...
September 18, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28921175/routine-gastric-residual-volume-measurement-and-energy-target-achievement-in-the-picu-a-comparison-study
#19
Lyvonne N Tume, Anna Bickerdike, Lynne Latten, Simon Davies, Madeleine H Lefèvre, Gaëlle W Nicolas, Frédéric V Valla
Critically ill children frequently fail to achieve adequate energy intake, and some care practices, such as the measurement of gastric residual volume (GRV), may contribute to this problem. We compared outcomes in two similar European Paediatric Intensive Care Units (PICUs): one which routinely measures GRV (PICU-GRV) to one unit that does not (PICU-noGRV). An observational pilot comparison study was undertaken. Eighty-seven children were included in the study, 42 (PICU-GRV) and 45 (PICU-noGRV). There were no significant differences in the percentage of energy targets achieved in the first 4 days of PICU admission although PICU-noGRV showed more consistent delivery of median (and IQR) energy targets and less under and over feeding for PICU-GRV and PICU-noGRV: day 1 37 (14-72) vs 44 (0-100), day 2 97 (53-126) vs 100 (100-100), day 3 84 (45-112) vs 100 (100-100) and day 4 101 (63-124) vs 100 (100-100)...
September 18, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28921165/erratum-to-prediction-of-vulnerability-to-bipolar-disorder-using-multivariate-neurocognitive-patterns-a-pilot-study
#20
Mon-Ju Wu, Benson Mwangi, Ives Cavalcante Passos, Isabelle E Bauer, Bo Cao, Thomas W Frazier, Giovana B Zunta-Soares, Jair C Soares
In the original version of this article (Wu et al. 2017), published on 1 September 2017, the name of author 'Bo Cao' was wrongly displayed. In this Erratum the incorrect name and correct name are shown. The original publication of this article has been corrected.
September 18, 2017: International Journal of Bipolar Disorders
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