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The beijing eye study

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https://www.readbyqxmd.com/read/28494563/-the-clinical-manifestations-and-imaging-characteristics-of-acute-syphilitic-posterior-placoid-chorioretinitis
#1
F Hu, X N Wang, X S Cao, X Y Peng
Objective: To investigate the clinical manifestations and imaging characteristics of acute syphilitic posterior placoid chorioretinitis (ASPPC). Methods: Retrospective study of 10 patients diagnosed ASPPC in the Department of Ophthalmology, Beijing Tongren Hospital from 2011 to 2016, including 6 males (10 eyes involved) and 4 females (8 eyes involved) with an age of (43.4±11.6) years (range, 26-60 years). Their clinical manifestations and imaging characteristics were summarized. Results: All 10 ASPPC patients complained about the reduction of visual acuity, and the majority of them had both eyes involved...
May 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28481929/horizontal-and-vertical-optic-disc-rotation-the-beijing-eye-study
#2
Yuan Yuan Fan, Jost B Jonas, Ya Xing Wang, Chang Xi Chen, Wen Bin Wei
PURPOSE: To measure the optic disc rotation around the vertical and horizontal disc axis and to evaluate associations with general and ocular parameters. DESIGN: Population-based study. METHODS: In the Beijing Eye Study, 3468 participants (mean age:64.6±9.8 years; range:50-93 years) underwent an ophthalmological examination which included spectral-domain optical coherence tomography (OCT) with enhanced depth imaging. Using the OCT images, we determined the amount of the rotation of the optic disc (defined as Bruch´s membrane opening (BMO)) around the vertical axis and horizontal axis...
2017: PloS One
https://www.readbyqxmd.com/read/28469101/retrospective-analysis-of-stevens-johnson-syndrome-and-toxic-epidermal-necrolysis-in-88-chinese-patients
#3
Li Wang, Xue-Ling Mei
BACKGROUND: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening diseases with high mortality rates. This study was designed to analyze the pathogenic factors, clinical manifestations, complications, treatment, and prognosis of SJS/TEN and to explore the differences between surviving and deceased patients. METHODS: SJS/TEN patients admitted to Beijing Friendship Hospital from January 2006 to December 2015 were included in the study...
May 5, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28448513/outdoor-activity-and-myopia-progression-in-4-year-follow-up-of-chinese-primary-school-children-the-beijing-children-eye-study
#4
Yin Guo, Li Juan Liu, Ping Tang, Yan Yun Lv, Yi Feng, Liang Xu, Jost B Jonas
PURPOSE: To investigate factors associated with ocular axial elongation and myopia progression during a 4-year follow-up in primary school children in Beijing. METHODS: This school-based study included 382 grade-1 children at baseline in 2011 (age:6.3±0.4 years) with 305 (79.8%) returning for the follow-up examination in 2015. At baseline and in yearly follow-up examinations, the children underwent a comprehensive eye examination including auto-refractometry, ocular biometry with measurement of axial length, and fundus photography...
2017: PloS One
https://www.readbyqxmd.com/read/28412803/-association-analysis-between-loxl1-gene-and-exfoliation-syndrome
#5
L Chen, N L Wang, S S Rong, L N Huang, H B Cheng
Objective: To evaluate the association of LOXL gene and XFS/XFG in Chinese population. Methods: Experimental research. Fifty unrelated patients from shenzhen Eye Hospital and Beijing Tongren Hospital with exfoliation syndrome or exfoliation glaucoma and 100 control subjects were included. All the seven exons and the splicing region were amplified by polymerase chain reaction (PCR) and were directly sequenced. The comparison of allelic frequencies and genotype frequencies between case and control groups was performed using standard χ(2) test...
April 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28355737/-clinical-features-and-prognostic-analysis-of-neuromyelitisoptica-spectrum-disease-with-sjogrensyndrome
#6
N Jia, Y Jing, Q C Li, L Liu, J W Wang, X M Hu
Objective: To explore the clinical features and conduct prognostic analysis about visual recovery and relapse of neuromyelitisoptica (NMO) spectrum disease (NMOSD) with sjogren syndrome (SS). Methods: A retrospective and prospective observational study was conducted.Between July 2013 and June 2016, 172 patients with NMOSD (NMOSD-non SS: 116/172, 67.4%; NMOSD-SS: 56/172, 32.6%) were assessed at Beijing Tongren Hospital, Capital Medical University, Beijing, China.The prognostic factors of NMOSD-SS patients were also analyzed...
March 21, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28260363/-clinical-features-treatment-and-prognosis-of-retinoblastoma-in-distant-metastasis-stage
#7
H M Hu, W L Zhang, Y Z Wang, J T Shi, B Li, Y Zhang, J Li, Y Wen, D S Huang
Objective: To summarize the clinical features, treatment and prognosis of retinoblastoma (RB) patients in distant metastasis stage. Methods: Retrospective case series study. Clinical data of 24 cases (30 eyes) with diagnosis of distant metastasis stage RB were collected in pediatrics department of Beijing Tongren Hospital affiliated with Capital Medical University, from September 2005 to December 2013. In these cases, including 11 male cases and 13 female cases, the treatment age ranged from 7 months to 9 years with the median of 26 months...
February 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28251820/peripapillary-choroidal-vascular-layers-the-beijing-eye-study
#8
Jie Xu, Ya Xing Wang, Ran Jiang, Wen Bin Wei, Liang Xu, Jost B Jonas
PURPOSE: To assess thickness and associations of the peripapillary choroidal layers. METHODS: The population-based Beijing Eye Study included 3468 participants with an age of 50+ years. Using spectral-domain optical coherence tomography, we measured the large vessel layer (LVL) and small-to-medium vessel layer (SMVL) of the peripapillary choroid in a circular scan with a diameter of 3.4 mm around the optic nerve head centre at eight locations equidistant (45°) to each other...
March 2, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28196733/the-proportion-of-individuals-likely-to-benefit-from-customized-optic-nerve-head-structure-function-mapping
#9
Allison M McKendrick, Jonathan Denniss, Ya Xing Wang, Jost B Jonas, Andrew Turpin
PURPOSE: Interindividual variance in optic nerve head (ONH) position, axial length, and location of the temporal raphe suggest that customizing mapping between visual field locations and ONH sectors for individuals may be clinically useful. Herein we quantify the proportion of the population predicted to have structure-function mappings that markedly deviate from "average," and thus would benefit from customized mapping. DESIGN: Database study and case report. PARTICIPANTS: Population database of 2836 eyes from the Beijing Eye Study and a single case report of an individual with primary open-angle glaucoma...
February 10, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28159853/vascular-flow-density-in-pathological-myopia-an-optical-coherence-tomography-angiography-study
#10
Jing Mo, Anli Duan, Szyyann Chan, Xuefei Wang, Wenbin Wei
OBJECTIVES: To investigate vascular flow density in pathological myopia with optical coherence tomography (OCT) angiography. DESIGN: A prospective comparative study was conducted from December 2015 to March 2016. SETTING: Participants were recruited in Beijing Tongren Hospital. PARTICIPANTS: A total of 131 eyes were enrolled, which were divided into three groups: 45 eyes with emmetropia (EM; mean spherical equivalent (MSE) 0...
February 3, 2017: BMJ Open
https://www.readbyqxmd.com/read/27852400/-diagnostic-performance-of-laser-retinal-imaging-in-the-epiretinal-membrane
#11
Y J Huo, L L Yang, W B Wei
Objective: To determine the diagnostic performance of confocal scanning laser ophthalmoscope (cSLO)-based retinal imaging in the epiretinal membrane (ERM) patients. Methods: Prospective case series study. Twenty-six patients (32 eyes) with ERM determined by spectral domain optical coherence tomography (SD-OCT) were recruited from June 2015 to October 2015 in the Beijing Tongren Eye Center. All subjects underwent retinal imaging using the cSLO-based Heidelberg MultiColor (Spectralis HRA-2; Heidelberg Engineering) technology and the traditional color fundus camera...
November 11, 2016: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/27806788/-treatment-and-prognostic-analysis-of-retinoblastoma-patients-with-choroid-invasion
#12
Y Z Wang, D S Huang, J T Shi, J M Ma, B Li, X L Xu, H M Hu, Y Zhou, H L Gu
Objective: To observe the treatment and prognosis of choroid invasion of retinoblastoma (RB) in children. Method: A total of 149 children who had been diagnosed with unilateral RB and received enucleation disclosing tumor invasion to choroid from January 2006 to December 2013 in Beijing Tongren Hospital were recruited in this study. Choroid involvement was classified as massive choroid invasion and focal choroid invasion. Massive choroid invasion was defined as a maximum diameter of invasive tumor focus of 3 mm or more in diameter that might reach the scleral tissue...
November 2, 2016: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/27760645/-the-clinical-and-histopathological-analysis-of-2-053-cases-of-conjunctival-neoplasms
#13
J J Huang, B Li, Q F Liang, X L Xu, F Gao, Z B Zhang
Objective: We aimed to identify and describe the clinical and histopathologic characteristics of conjunctival neoplasms. Methods: Retrospective case series study. We collected and analyzed the clinical and histopathologic data of the conjunctival neoplastic specimens including the age, gender, and histopathologic diagnosis of all patients obtained from Beijing Tongren Eye Center between October 2003 and October 2015. All the pathology diagnosis results were divided into two categories which were benign and malignant tumors, according to Shields histopathological classification methods and the pathology diagnosis results in our department...
October 11, 2016: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/27760263/analysis-of-cerebrospinal-fluid-pressure-estimation-using-formulae-derived-from-clinical-data
#14
RANDOMIZED CONTROLLED TRIAL
David Fleischman, Amanda K Bicket, Sandra S Stinnett, John P Berdahl, Jost B Jonas, Ning Li Wang, Michael P Fautsch, R Rand Allingham
Purpose: To evaluate a frequently used regression model and a new, modified regression model to estimate cerebrospinal fluid pressure (CSFP). Methods: Datasets from the Beijing iCOP study from Tongren Hospital, Beijing, China, and the Mayo Clinic, Rochester, Minnesota, were tested in this retrospective, case-control study. An often-used regression model derived from the Beijing iCOP dataset, but without radiographic data, was used to predict CSFP by using demographic and physiologic data...
October 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27412741/-clinical-and-electroencephalographic-analysis-of-anti-n-methyl-d-aspartate-receptor-encephalitis-in-children
#15
H Li, X H Wang, F Fang, C H Ding, J L Lyu, C H Chen, T L Han, Y Wu, W H Zhang, J W Li, H M Wang, X Y Yang, S Zhang, J Deng, S Gong, X Sun, L F Dai
OBJECTIVE: To study the clinical and electroencephalographic (EEG) characteristics of anti-N-methyl-D-aspartate receptor encephalitis (anti-NMDAR encephalitis) in children. METHOD: Retrospective analysis was performed on the clinical and EEG data of 105 patients with anti-NMDAR encephalitis treated in Beijing Children's Hospital (August 2011-March 2015). Of the 105 patients, 38 were male and 67 were female.The age of onset was from 6 months and 26 days to 15 years and 8 months (average (8±4)years)...
July 2016: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/27372909/evaluation-of-macular-ganglion-cell-complex-and-peripapillary-retinal-nerve-fiber-layer-in-primary-craniopharyngioma-by-fourier-domain-optical-coherence-tomography
#16
Liu Yang, Yuanzhen Qu, Wen Lu, Fengjun Liu
BACKGROUND The aim of this study was to compare the differences in macular ganglion cell complex (GCC) and peripapillary retinal nerve fiber layer (pRNFL) in child and adult patients with primary craniopharyngioma by Fourier-domain optical coherence tomography (FD-OCT) and to evaluate their significance in the diagnosis of primary craniopharyngioma. MATERIAL AND METHODS Ninety-six participants were divided into 3 groups: 32 in the child craniopharyngioma group (CCG) and 32 in the adult craniopharyngioma group (ACG) who were treated in Beijing Tiantan Hospital between November 2013 and October 2014, and 32 in the normal group (NG)...
July 3, 2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/27225260/molecular-characteristics-of-the-ompa-gene-of-serotype-b-chlamydia-trachomatis-in-qinghai-tibetan-primary-school-students
#17
Xue Li, Shaoya Zhang, Qingfeng Liang, Mei Wang, Ailian Hu, Xiuyuan Li, Benshan Yang, Mingxin Zhang, Ningli Wang, Xinxin Lu
To study the molecular characteristics of Chlamydia trachomatis, the major outer membrane protein gene (ompA) of C. trachomatis from primary school students with trachoma residing in the Qinghai Tibetan area was sequenced and compared with the same serotype in GenBank. In Jianshetang Primary School and Galeng Central Primary School in the Galeng Tibetan Township of Qinghai Haidong Sala Autonomous County, scraped samples were collected from the upper tarsal conjunctiva and lower conjunctival sac of both eyes of 45 students with trachoma, stored at 4°C, and transported to Beijing Tongren Hospital by air within 24 h...
June 2016: Science China. Life Sciences
https://www.readbyqxmd.com/read/27220707/-comparative-analysis-of-the-characteristics-of-bilateral-rhegmatogenous-retinal-detachment
#18
Jinqiong Zhou, Wenbin Wei, Qisheng You, Ying Tu
OBJECTIVE: To investigate the characteristics of bilateral rhegmatogenous retinal detachment (RRD) in a hospital-based population. METHODS: Six hundred and three patients diagnosed with bilateral RRD in the Beijing Tongren Hospital between January 2000 and January 2014 were identified and included into the study. The clinical features including the age when retinal detachment occurrence, time interval between the occurrence of the bilateral RRDs, predisposing characteristics such as myopia, trauma, et al...
May 2016: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/27152764/education-related-parameters-in-high-myopia-adults-versus-school-children
#19
Jost B Jonas, Liang Xu, Ya Xing Wang, Hong Sheng Bi, Jian Feng Wu, Wen Jun Jiang, Vinay Nangia, Ajit Sinha, Dan Zhu, Yong Tao, Yin Guo, Qi Sheng You, Li Juan Wu, Li Xin Tao, Xiu Hua Guo, Kyoko Ohno-Matsui, Songhomitra Panda-Jonas
PURPOSE: Since high myopia in the younger generation may differ etiologically from high myopia in older generations, we examined whether education-related parameters differ between high myopia in today´s school children and high pathological myopia in today´s elderly generation. METHODS: The investigation included the adult populations of the population-based Beijing Eye Study (BES) (3468 adults;mean age:64.6±9.8years;range:50-93years) and Central India Eye and Medical Study (CIEMS) (4711 adults;age:49...
2016: PloS One
https://www.readbyqxmd.com/read/27100659/corneal-curvature-radius-in-myopia-of-schoolchildren-versus-adult-myopia
#20
COMPARATIVE STUDY
Jost B Jonas, Hong Sheng Bi, Jian Feng Wu, Liang Xu, Ya Xing Wang, Wen Bin Wei, Vinay Nangia, Ajit Sinha, Yin Guo, Qi Sheng You, Kyoko Ohno-Matsui, Songhomitra Panda-Jonas
PURPOSE: To assess whether anterior corneal curvature radius (CCR) is associated with the increased prevalence of myopia in Asia. METHODS: The investigation included the adult populations of the Central India Eye and Medical Study (CIEMS; 4711 adults) and Beijing Eye Study (BES; 3468 adults) and the children and teenager populations of the Shandong Children Eye Study (6026 children; age: 9.7 ± 3.3 years; range: 4-18 years) and Beijing Pediatric Eye Study (681 children; age: 7...
October 2016: Cornea
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